<Journal class="Journal" value="Curr Opin Biotechnol" /> <Page class="#txt" value="390"> <Page-2 class="#txt" value="7" /> </Page> <Volume class="#txt" value="13" /> <Year class="Year" value="2002" /> </Reference> <Comment class="#Text" value="This classification was updated by <A href=http://bioweb.supagro.inra.fr/ESTHER/paper?name=Jaeger_2002_Curr.Opin.Biotechnol_13_390&class=Paper>Jaeger and Eggert</A> in 2002, Hausmann and Jaeger (2010), Kovacic, Krauss and Jaeger (2019). See the correspondance with ESTHER (<A href=http://bioweb.supagro.inra.fr/ESTHER/Arpigny_Jaeger.table>Table</A>). 6 out of the 8 families described in the orginal paper belong to alpha beta hydrolases. (I III <A href=http://bioweb.supagro.inra.fr/ESTHER/family?name=Bacterial_lipase&class=Family>Bacterial_lipase</A>, IV HSL <A href=http://bioweb.supagro.inra.fr/ESTHER/family?name=Hormone-sensitive_lipase_like&class=Family>Hormone-sensitive_lipase_like</A>, V <A href=http://bioweb.supagro.inra.fr/ESTHER/family?name=Pha_depolymerase&class=Family>Pha_depolymerase</A>, VI <A href=http://bioweb.supagro.inra.fr/ESTHER/family?name=LYsophospholipase_carboxylesterase&class=Family>LYsophospholipase_carboxylesterase</A>, VII <A href=http://bioweb.supagro.inra.fr/ESTHER/family?name=Carboxylesterase&class=Family>Carboxylesterase</A>). Family II is the closely related GDSL family (GNSH hydrolases not alpha/beta hydrolases) and family VIII is beta lactamase with sequences which contain a GXSXG motif in the c-terminal part of the protein but are not alpha-beta hydrolases. The original classification in 8 families was further extended. Family I was subdivided in 7 subfamilies by <A href=http://bioweb.supagro.inra.fr/ESTHER/paper?name=Jaeger_2002_Curr.Opin.Biotechnol_13_390&class=Paper>Jaeger and Eggert (2002)</A>. Family IX was introduced by <A href=http://bioweb.supagro.inra.fr/ESTHER/paper?name=Handrick_2001_J.Biol.Chem_276_36215&class=Paper> Handrick et al.(2001)</A>. Family X was introduced by <A href=http://bioweb.supagro.inra.fr/ESTHER/paper?name=Levisson_2007_FEBS.J_274_2832&class=Paper>Levisson et al. 2007</A>, <A href=http://bioweb.supagro.inra.fr/ESTHER/paper?name=Bassegoda_2012_Appl.Environ.Microbiol_78_1724&class=Paper>Bassegoda et al. 2012</A>). Family XI was introduced by <A href=http://bioweb.supagro.inra.fr/ESTHER/paper?name=Lee_2006_Appl.Environ.Microbiol_72_7406&class=Paper>Lee et al.(2006)</A>. Family XII was introduced by <A href=http://bioweb.supagro.inra.fr/ESTHER/paper?name=Kim_2009_Appl.Environ.Microbiol_75_257&class=Paper>Kim et al. (2009)</A> Family XIII was introduced by <A href=http://bioweb.supagro.inra.fr/ESTHER/paper?name=Ewis_2004_Gene_329_187&class=Paper>Ewis et al.(2004)</A> and <A href=http://bioweb.supagro.inra.fr/ESTHER/paper?name=Liu_2004_J.Mol.Biol_342_551&class=Paper>Liu et al.(2004)</A> and was divided in two by <A href=http://bioweb.supagro.inra.fr/ESTHER/paper?name=Charbonneau_2013_PLoS.One_8_e76675&class=Paper>Charbonneau et al.(2013)</A> Family XIV was introduced by <A href=http://bioweb.supagro.inra.fr/ESTHER/paper?name=Rao_2011_Biochim.Biophys.Acta_1814_1695&class=Paper>Rao et al.(2011)</A>. Family XV was introduced by <A href=http://bioweb.supagro.inra.fr/ESTHER/paper?name=Bayer_2010_J.Mol.Microbiol.Biotechnol_18_181&class=Paper>Bayer et al.(2010)</A> and <A href=http://bioweb.supagro.inra.fr/ESTHER/paper?name=Lee_2010_Appl.Microbiol.Biotechnol_88_1125&class=Paper>Lee et al. (2010)</A>. Family XVI was introduced by <A href=http://bioweb.supagro.inra.fr/ESTHER/paper?name=Fu_2013_Appl.Microbiol.Biotechnol_97_3965&class=Paper>Fu et al.(2013)</A>" /> <Author class="Author" value="Jaeger KE" /> <Author class="Author" value="Eggert T" /> <Medline class="Medline" value="12323363" /> <Abstract class="LongText" value="Jaeger_2002_Curr.Opin.Biotechnol_13_390" /> <Arpigny_Jaeger class="Arpigny_Jaeger" value="Family_V.3" /> <Arpigny_Jaeger class="Arpigny_Jaeger" value="Family_X.1" /> <Arpigny_Jaeger class="Arpigny_Jaeger" value="Family_X.2" /> <Arpigny_Jaeger class="Arpigny_Jaeger" value="Family_V.1" /> <Arpigny_Jaeger class="Arpigny_Jaeger" value="Family_I" /> <Arpigny_Jaeger class="Arpigny_Jaeger" value="Family I.1" /> <Arpigny_Jaeger class="Arpigny_Jaeger" value="Family_I.2" /> <Arpigny_Jaeger class="Arpigny_Jaeger" value="Family_I.3" /> <Arpigny_Jaeger class="Arpigny_Jaeger" value="Family_I.5" /> <Arpigny_Jaeger class="Arpigny_Jaeger" value="Family_I.6" /> <Arpigny_Jaeger class="Arpigny_Jaeger" value="Family_V.2" /> <Arpigny_Jaeger class="Arpigny_Jaeger" value="Family_VI" /> <Arpigny_Jaeger class="Arpigny_Jaeger" value="Family_II" /> <Arpigny_Jaeger class="Arpigny_Jaeger" value="Family_VIII" /> </Paper>