2004

Handrick_2004_J.Bacteriol_186_7243 The intracellular poly(3-hydroxybutyrate) (PHB) depolymerase of Rhodospirillum rubrum is a periplasm-located protein with specificity for native PHB and with structural similarity to extracellular PHB depolymerases
Hillier_2004_Nature_432_695 Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution
Topakas_2004_Appl.Microbiol.Biotechnol_63_686 Purification and characterization of a type B feruloyl esterase (StFAE-A) from the thermophilic fungus Sporotrichum thermophile
Chien_2004_Science_305_1966 The genomic sequence of the accidental pathogen Legionella pneumophila
Cazalet_2004_Nat.Genet_36_1165 Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity
Carmody_2004_Gene_343_107 Analysis and manipulation of amphotericin biosynthetic genes by means of modified phage KC515 transduction techniques
Brikun_2004_J.Ind.Microbiol.Biotechnol_31_335 The erythromycin biosynthetic gene cluster of Aeromicrobium erythreum
Brede_2004_Appl.Environ.Microbiol_70_7303 Molecular and genetic characterization of propionicin F, a bacteriocin from Propionibacterium freudenreichii
Bililign_2004_Chem.Biol_11_959 The hedamycin locus implicates a novel aromatic PKS priming mechanism
Olano_2004_Chem.Biol_11_87 Biosynthesis of the angiogenesis inhibitor borrelidin by Streptomyces parvulus Tu4055: cluster analysis and assignment of functions
Broker_2004_J.Bacteriol_186_212 Characterization of the 101-kilobase-pair megaplasmid pKB1, isolated from the rubber-degrading bacterium Gordonia westfalica Kb1
Ishikawa_2004_Proc.Natl.Acad.Sci.U.S.A_101_14925 The complete genomic sequence of Nocardia farcinica IFM 10152
Hallam_2004_Science_305_1457 Reverse methanogenesis: testing the hypothesis with environmental genomics
Piel_2004_Proc.Natl.Acad.Sci.U.S.A_101_16222 Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei
Lee_2004_Appl.Microbiol.Biotechnol_65_720 Screening for novel lipolytic enzymes from uncultured soil microorganisms
Muller_2004_Appl.Environ.Microbiol_70_2332 Oxygen-controlled bacterial growth in the sponge Suberites domuncula: toward a molecular understanding of the symbiotic relationships between sponge and bacteria
Giraud_2004_J.Biol.Chem_279_15076 Two distinct crt gene clusters for two different functional classes of carotenoid in Bradyrhizobium
Romen_2004_Arch.Microbiol_182_157 Thermotolerant poly(3-hydroxybutyrate)-degrading bacteria from hot compost and characterization of the PHB depolymerase of Schlegelella sp. KB1a
Leveau_2004_Environ.Microbiol_6_990 Phylogeny-function analysis of (meta)genomic libraries: screening for expression of ribosomal RNA genes by large-insert library fluorescent in situ hybridization (LIL-FISH)
de Koning_2004_Eukaryot.Cell_3_1198 Nucleus-encoded genes for plastid-targeted proteins in Helicosporidium: functional diversity of a cryptic plastid in a parasitic alga
Chang_2004_J.Nat.Prod_67_1356 Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula
Edwards_2004_Chem.Biol_11_817 Structure and biosynthesis of the jamaicamides, new mixed polyketide-peptide neurotoxins from the marine cyanobacterium Lyngbya majuscula
Sandmann_2004_Chem.Biol_11_1071 Identification and analysis of the core biosynthetic machinery of tubulysin, a potent cytotoxin with potential anticancer activity
Xie_2004_J.Fish.Dis_27_719 Characterization of two membrane-associated protease genes obtained from screening out-membrane protein genes of Flavobacterium columnare G4
Sabehi_2004_Environ.Microbiol_6_903 Different SAR86 subgroups harbour divergent proteorhodopsins
Noumura_2004_FEMS.Microbiol.Lett_239_147 Genetic characterization of the dibenzofuran-degrading Actinobacteria carrying the dbfA1A2 gene homologues isolated from activated sludge
Habe_2004_J.Bacteriol_186_5938 Characterization of the upper pathway genes for fluorene metabolism in Terrabacter sp. strain DBF63
Gunsior_2004_Chem.Biol_11_927 The biosynthetic gene cluster for a monocyclic beta-lactam antibiotic, nocardicin A
Rouhiainen_2004_Appl.Environ.Microbiol_70_686 Genes coding for hepatotoxic heptapeptides (microcystins) in the cyanobacterium Anabaena strain 90
Cheng_2004_Bioorg.Chem_32_92 Characterization of two polyketide synthase genes in Exophiala lecanii-corni, a melanized fungus with bioremediation potential
Moriwaki_2004_FEMS.Microbiol.Lett_238_1 Insertional mutagenesis and characterization of a polyketide synthase gene (PKS1) required for melanin biosynthesis in Bipolaris oryzae
Huang_2004_FEMS.Microbiol.Lett_232_197 Identification and characterization of pltZ, a gene involved in the repression of pyoluteorin biosynthesis in Pseudomonas sp. M18
Zirkle_2004_DNA.Seq_15_123 Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus
Quyen_2004_Mol.Genet.Genomics_272_538 A novel lipase\/chaperone pair from Ralstonia sp. M1: analysis of the folding interaction and evidence for gene loss in R. solanacearum
Buchan_2004_Appl.Environ.Microbiol_70_1658 Diverse organization of genes of the beta-ketoadipate pathway in members of the marine Roseobacter lineage
Inoue_2004_Biosci.Biotechnol.Biochem_68_1467 Divergent structures of carbazole degradative car operons isolated from gram-negative bacteria
Muller_2004_Appl.Environ.Microbiol_70_6066 Genetic analysis of phenoxyalkanoic acid degradation in Sphingomonas herbicidovorans MH
Seo_2004_Nature_431_67 Hox cluster disintegration with persistent anteroposterior order of expression in Oikopleura dioica
Barbe_2004_Nucleic.Acids.Res_32_5766 Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium
Girlich_2004_Antimicrob.Agents.Chemother_48_4217 OXA-60, a chromosomal, inducible, and imipenem-hydrolyzing class D beta-lactamase from Ralstonia pickettii
Mihara_2004_Microbiology_150_2587 Identification and transcriptional organization of a gene cluster involved in biosynthesis and transport of acinetobactin, a siderophore produced by Acinetobacter baumannii ATCC 19606T
Li_2004_Chem.Biol_11_107 Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase
Sosio_2004_Microbiology_150_95 Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus
Tsuge_2004_Macromol.Biosci_4_238 Biosynthesis and compositional regulation of poly[(3-hydroxybutyrate)-co-(3-hydroxyhexanoate)] in recombinant ralstonia eutropha expressing mutated polyhydroxyalkanoate synthase genes
Bartlam_2004_Structure.(Camb)_12_1481 Crystal Structure of an Acylpeptide Hydrolase\/Esterase from Aeropyrum pernix K1.
Rui_2004_J.Biol.Chem_279_46810 Active site engineering of the epoxide hydrolase from Agrobacterium radiobacter AD1 to enhance aerobic mineralization of cis-1,2-dichloroethylene in cells expressing an evolved toluene ortho-monooxygenase
van Loo_2004_Chem.Biol_11_981 Directed evolution of epoxide hydrolase from A. radiobacter toward higher enantioselectivity by error-prone PCR and DNA shuffling
Ro_2004_FEMS.Microbiol.Lett_233_97 Genome-wide cloning and characterization of microbial esterases
Jencova_2004_Int.Biodeterior.Biodegradation_54_175 Chlorocatechol catabolic enzymes from Achromobacter xylosoxidans A8
Potter_2004_Microbiology_150_2301 The complex structure of polyhydroxybutyrate (PHB) granules: four orthologous and paralogous phasins occur in Ralstonia eutropha
Trefault_2004_Environ.Microbiol_6_655 Genetic organization of the catabolic plasmid pJP4 from Ralstonia eutropha JMP134 (pJP4) reveals mechanisms of adaptation to chloroaromatic pollutants and evolution of specialized chloroaromatic degradation pathways
De Simone_2004_J.Biol.Chem_279_6815 A substrate-induced switch in the reaction mechanism of a thermophilic esterase: kinetic evidences and structural basis
De Simone_2004_J.Mol.Biol_343_137 The crystal structure of an EST2 mutant unveils structural insights on the H group of the carboxylesterase\/lipase family
Weill_2004_Insect.Mol.Biol_13_1 The unique mutation in ace-1 giving high insecticide resistance is easily detectable in mosquito vectors
Li_2004_Insect.Biochem.Mol.Biol_34_397 Mutations in acetylcholinesterase associated with insecticide resistance in the cotton aphid, Aphis gossypii Glover
Toda_2004_Insect.Mol.Biol_13_549 Two amino acid substitutions in acetylcholinesterase associated with pirimicarb and organophosphorous insecticide resistance in the cotton aphid, Aphis gossypii Glover (Homoptera: Aphididae)
Andrews_2004_Insect.Mol.Biol_13_555 Identification of mutations conferring insecticide-insensitive AChE in the cotton-melon aphid, Aphis gossypii Glover
Wright_2004_Mol.Biol.Evol_21_1719 Effects of gene expression on molecular evolution in Arabidopsis thaliana and Arabidopsis lyrata
Ryu_2004_Trends.Plant.Sci_9_229 Phospholipid-derived signaling mediated by phospholipase A in plants
Lo_2004_Plant.Physiol_135_947 Characterization of an ultraviolet B-induced lipase in Arabidopsis
Noiriel_2004_Eur.J.Biochem_271_3752 Expression in yeast of a novel phospholipase A1 cDNA from Arabidopsis thaliana
Stahl_2004_Plant.Physiol_135_1324 Cloning and functional characterization of a phospholipid:diacylglycerol acyltransferase from Arabidopsis
Gong_2004_Plant.Physiol_135_773 Genome-wide ORFeome cloning and analysis of Arabidopsis transcription factor genes
Milkowski_2004_Phytochemistry_65_517 Serine carboxypeptidase-like acyltransferases
Castelli_2004_Genome.Res_14_406 Whole genome sequence comparisons and full-length cDNA sequences: a combined approach to evaluate and improve Arabidopsis genome annotation
Nuhse_2004_Plant.Cell_16_2394 Phosphoproteomics of the Arabidopsis plasma membrane and a new phosphorylation site database
Frerichs-Deeken_2004_Biochemistry_43_14485 Dioxygenases without requirement for cofactors and their chemical model reaction: compulsory order ternary complex mechanism of 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase involving general base catalysis by histidine 251 and single-electron oxidation of the substrate dianion
Dietrich_2004_Science_304_304 The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome
Ehrlich_2004_Appl.Environ.Microbiol_70_6518 Aflatoxin biosynthesis cluster gene cypA is required for G aflatoxin formation
Fujii_2004_J.Biol.Chem_279_44613 Hydrolytic polyketide shortening by ayg1p, a novel enzyme involved in fungal melanin biosynthesis
Pain_2004_Fungal.Genet.Biol_41_443 Insight into the genome of Aspergillus fumigatus: analysis of a 922 kb region encompassing the nitrate assimilation gene cluster
Levasseur_2004_Protein.Expr.Purif_37_126 Homologous expression of the feruloyl esterase B gene from Aspergillus niger and characterization of the recombinant enzyme
Bourne_2004_Structure_12_677 Aspergillus niger protein EstA defines a new class of fungal esterases within the alpha\/beta hydrolase fold superfamily of proteins
Schrag_2004_Structure.(Camb)_12_521 Defining substrate characteristics from 3D structure\; perspective on EstA structure
Hermoso_2004_J.Mol.Biol_338_495 The crystal structure of feruloyl esterase A from Aspergillus niger suggests evolutive functional convergence in feruloyl esterase family
McAuley_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_878 Structure of a feruloyl esterase from Aspergillus niger
Reetz_2004_Org.Lett_6_177 Enhancing the enantioselectivity of an epoxide hydrolase by directed evolution
Yu_2004_Appl.Environ.Microbiol_70_1253 Clustered pathway genes in aflatoxin biosynthesis
Yu_2004_FEBS.Lett_564_126 Completed sequence of aflatoxin pathway gene cluster in Aspergillus parasiticus
Zhang_2004_Appl.Environ.Microbiol_70_6875 Indole-diterpene gene cluster from Aspergillus flavus
Zhong_2004_Protein.Expr.Purif_36_165 Secretion, purification, and characterization of a recombinant Aspergillus oryzae tannase in Pichia pastoris
Chang_2004_Appl.Environ.Microbiol_70_3593 The Aspergillus parasiticus estA-encoded esterase converts versiconal hemiacetal acetate to versiconal and versiconol acetate to versiconol in aflatoxin biosynthesis
Park_2004_Cell.Mol.Life.Sci_61_2878 Terrein: a new melanogenesis inhibitor and its mechanism
Takami_2004_Extremophiles_8_351 Genomic characterization of thermophilic Geobacillus species isolated from the deepest sea mud of the Mariana Trench
Takami_2004_Nucleic.Acids.Res_32_6292 Thermoadaptation trait revealed by the genome sequence of thermophilic Geobacillus kaustophilus
Koumoutsi_2004_J.Bacteriol_186_1084 Structural and functional characterization of gene clusters directing nonribosomal synthesis of bioactive cyclic lipopeptides in Bacillus amyloliquefaciens strain FZB42
Hoffmaster_2004_Proc.Natl.Acad.Sci.U.S.A_101_8449 Identification of anthrax toxin genes in a Bacillus cereus associated with an illness resembling inhalation anthrax
Rasko_2004_Nucleic.Acids.Res_32_977 The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1
Kessler_2004_J.Biol.Chem_279_7413 The linear pentadecapeptide gramicidin is assembled by four multimodular nonribosomal peptide synthetases that comprise 16 modules with 56 catalytic domains
Kuwahara_2004_Proc.Natl.Acad.Sci.U.S.A_101_14919 Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation
Rey_2004_Genome.Biol_5_R77 Complete genome sequence of the industrial bacterium Bacillus licheniformis and comparisons with closely related Bacillus species
Veith_2004_J.Mol.Microbiol.Biotechnol_7_204 The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential
Kim_2004_J.Mol.Catal.B.Enzym_27_237 Occurrence of ofloxacin ester-hydrolyzing esterase from Bacillus niacini EM001.
Takimoto_2004_Appl.Microbiol.Biotechnol_65_263 Batch production of deacetyl 7-aminocephalosporanic acid by immobilized cephalosporin-C deacetylase
Rajakumara_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_160 Crystallization and preliminary X-ray crystallographic investigations on several thermostable forms of a Bacillus subtilis lipase
Acharya_2004_J.Mol.Biol_341_1271 Structural basis of selection and thermostability of laboratory evolved Bacillus subtilis lipase
Moyne_2004_FEMS.Microbiol.Lett_234_43 Molecular characterization and analysis of the operon encoding the antifungal lipopeptide bacillomycin D
Janda_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_1101 Harvesting the high-hanging fruit: the structure of the YdeN gene product from Bacillus subtilis at 1.8 angstroms resolution
Schlieben_2004_Protein.Expr.Purif_34_103 Expression, purification, and aggregation studies of His-tagged thermoalkalophilic lipase from Bacillus thermocatenulatus
Alsmark_2004_Proc.Natl.Acad.Sci.U.S.A_101_9716 The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae
Rendulic_2004_Science_303_689 A predator unmasked: life cycle of Bdellovibrio bacteriovorus from a genomic perspective
Tartar_2004_Mycopathologia_158_201 A pilot-scale expressed sequence tag analysis of Beauveria bassiana gene expression reveals a tripeptidyl peptidase that is differentially expressed in vivo
Takahashi-Ando_2004_Appl.Environ.Microbiol_70_3239 Metabolism of zearalenone by genetically modified organisms expressing the detoxification gene from Clonostachys rosea
Temeyer_2004_J.Med.Entomol_41_259 Identification of a third Boophilus microplus (Acari: Ixodidae) cDNA presumptively encoding an acetylcholinesterase
Katona_2004_J.Bacteriol_186_6443 The fur homologue in Borrelia burgdorferi
Ruddock_2004_Biol.Reprod_70_1131 Analysis of imprinted messenger RNA expression during bovine preimplantation development
Milkowski_2004_Plant.J_38_80 Molecular regulation of sinapate ester metabolism in Brassica napus: expression of genes, properties of the encoded proteins and correlation of enzyme activities with metabolite accumulation
Nair_2004_J.Clin.Invest_113_464 Salicylate induces an antibiotic efflux pump in Burkholderia cepacia complex genomovar III (B. cenocepacia)
Nierman_2004_Proc.Natl.Acad.Sci.U.S.A_101_14246 Structural flexibility in the Burkholderia mallei genome
Holden_2004_Proc.Natl.Acad.Sci.U.S.A_101_14240 Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei
Di Gregorio_2004_Biodegradation_15_111 Identification of two new sets of genes for dibenzothiophene transformation in Burkholderia sp. DBT1
Bimonte_2004_Eur.J.Neurosci_20_1483 Mutation of the feh-1 gene, the Caenorhabditis elegans orthologue of mammalian Fe65, decreases the expression of two acetylcholinesterase genes
Inoue_2004_Proc.Natl.Acad.Sci.U.S.A_101_13233 Type II platelet-activating factor-acetylhydrolase is essential for epithelial morphogenesis in Caenorhabditis elegans
Kwon_2004_Genomics_83_600 Ethanol-response genes and their regulation analyzed by a microarray and comparative genomic approach in the nematode Caenorhabditis elegans
Jones_2004_Proc.Natl.Acad.Sci.U.S.A_101_7329 The diploid genome sequence of Candida albicans
Larios_2004_Appl.Microbiol.Biotechnol_65_373 Synthesis of flavor and fragrance esters using Candida antarctica lipase
Moreau_2004_Biotechnol.Lett_26_419 Synthesis of novel D-glucuronic acid fatty esters using Candida antarctica lipase in tert-butanol
Noel_2004_Biotechnol.Lett_26_301 Kinetic resolution of rac-2-pentanol catalyzed by Candida antarctica lipase B in the ionic liquid, 1-butyl-3-methylimidazolium bis[(trifluoromethyl)sulfonyl]amide
Passicos_2004_Biotechnol.Lett_26_1073 Regioselective acylation of flavonoids catalyzed by immobilized Candida antarctica lipase under reduced pressure
Rejasse_2004_Org.Biomol.Chem_2_1086 Stability improvement of immobilized Candida antarctica lipase B in an organic medium under microwave radiation
Roberts_2004_Green.Chem_6_475 Lipase catalysed resolution of the Lotrafiban intermediate 2,3,4,5-tetrahydro-4-methyl-3-oxo-1 H-1,4-benzodiazepine-2-acetic acid methyl ester in ionic liquids: comparison to the industrial t-butanol process
Dujon_2004_Nature_430_35 Genome evolution in yeasts
Brunel_2004_J.Biotechnol_111_41 High-level expression of Candida parapsilosis lipase\/acyltransferase in Pichia pastoris
Rogers_2004_J.Eukaryot.Microbiol_51_529 Plastid-targeting peptides from the chlorarachniophyte Bigelowiella natans
Schleheck_2004_Appl.Environ.Microbiol_70_4053 Mineralization of individual congeners of linear alkylbenzenesulfonate by defined pairs of heterotrophic bacteria
Mampel_2004_Biochem.J_383_91 A novel outer-membrane anion channel (porin) as part of a putatively two-component transport system for 4-toluenesulphonate in Comamonas testosteroni T-2
Abrahamsen_2004_Science_304_441 Complete genome sequence of the apicomplexan, Cryptosporidium parvum
Xu_2004_Nature_431_1107 The genome of Cryptosporidium hominis
Buss_2004_Insect.Biochem.Mol.Biol_34_433 Molecular comparisons of the Culex pipiens (L.) complex esterase gene amplicons
Li_2004_Ji.Sheng.Chong.Yu.Yi.Xue.Kun.Chong.Xue.Bao_11_161 Cloning of culex pipiens pallens cDNA encoding acetylcholinesterase and homology modeling of ache.
Smith_2004_Am.J.Trop.Med.Hyg_70_339 Rapid assays for identification of members of the Culex (Culex) pipiens complex, their hybrids, and other sibling species (Diptera: culicidae)
Nabeshima_2004_Biochem.Biophys.Res.Commun_313_794 An amino acid substitution attributable to insecticide-insensitivity of acetylcholinesterase in a Japanese encephalitis vector mosquito, Culex tritaeniorhynchus
Reuveny_2004_Arch.Insect.Biochem.Physiol_57_92 Evaluation of mechanisms of azinphos-methyl resistance in the codling moth Cydia pomonella (L.)
Behra_2004_Toxicol.Sci_77_325 The use of zebrafish mutants to identify secondary target effects of acetylcholine esterase inhibitors
Behra_2004_7th.ChE.Meeting.Pucon__327 Poster (12) Acetylcholinesterase is required for neuronal and muscular development in the zebra fish embryo
Behra_2004_7th.ChE.Meeting.Pucon__368 Poster (91) The zebrafish as a model to study off target effects of AChE inhibitors.
Behra_2004_Cholinergic.Mechanisms.CRC.Press__467 A zebrafish mutant as a model for an acetylcholinesterase-deficient vertebrate.
Downes_2004_Dev.Biol_270_232 Acetylcholinesterase function is dispensable for sensory neurite growth but is critical for neuromuscular synapse stability
Amsterdam_2004_Proc.Natl.Acad.Sci.U.S.A_101_12792 Identification of 315 genes essential for early zebrafish development
Song_2004_Proc.Natl.Acad.Sci.U.S.A_101_16240 Hematopoietic gene expression profile in zebrafish kidney marrow
Printes_2004_Environ.Toxicol.Chem_23_1241 A comparative study on the relationship between acetylcholinesterase activity and acute toxicity in Daphnia magna exposed to anticholinesterase insecticides
Rabus_2004_Environ.Microbiol_6_887 The genome of Desulfotalea psychrophila, a sulfate-reducing bacterium from permanently cold Arctic sediments
Heidelberg_2004_Nat.Biotechnol_22_554 The genome sequence of the anaerobic, sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough
Lazari_2004_Mol.Biochem.Parasitol_136_313 A putative neuromuscular acetylcholinesterase gene from Dictyocaulus viviparus
Maside_2004_Curr.Biol_14_150 Selection on codon usage in Drosophila americana
Kawahara_2004_Genes.Genet.Syst_79_351 Comparative sequence analysis of a gene-dense region among closely related species of Drosophila melanogaster
Gerber_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_531 Crystallization and preliminary X-ray analysis of Aes, an acetyl-esterase from Escherichia coli
Grozdanov_2004_J.Bacteriol_186_5432 Analysis of the genome structure of the nonpathogenic probiotic Escherichia coli strain Nissle 1917
Azpiroz_2004_Antimicrob.Agents.Chemother_48_1235 Involvement of enterobactin synthesis pathway in production of microcin H47
Boyd_2004_Antimicrob.Agents.Chemother_48_3758 Complete nucleotide sequence of a 92-kilobase plasmid harboring the CTX-M-15 extended-spectrum beta-lactamase involved in an outbreak in long-term-care facilities in Toronto, Canada
Schneider_2004_Infect.Immun_72_5993 The pathogenicity island-associated K15 capsule determinant exhibits a novel genetic structure and correlates with virulence in uropathogenic Escherichia coli strain 536
Smit_2004_Trends.Biotechnol_22_123 Fungal epoxide hydrolases: new landmarks in sequence-activity space
Bell_2004_Proc.Natl.Acad.Sci.U.S.A_101_11105 Genome sequence of the enterobacterial phytopathogen Erwinia carotovora subsp. atroseptica and characterization of virulence factors
Gilmore_2004_Microb.Pathog_37_205 Identification of Francisella tularensis genes encoding exported membrane-associated proteins using TnphoA mutagenesis of a genomic library
Ewis_2004_Gene_329_187 Molecular cloning and characterization of two thermostable carboxyl esterases from Geobacillus stearothermophilus
Liu_2004_J.Mol.Biol_342_551 Covalent reaction intermediate revealed in crystal structure of the Geobacillus stearothermophilus carboxylesterase Est30
Leow_2004_Biosci.Biotechnol.Biochem_68_96 High level expression of thermostable lipase from Geobacillus sp. strain T1
Hens_2004_Insect.Biochem.Mol.Biol_34_1281 Cloning and expression of the yolk protein of the tsetse fly Glossina morsitans morsitans
Baliga_2004_Genome.Res_14_2221 Genome sequence of Haloarcula marismortui: a halophilic archaeon from the Dead Sea
Gruber_2004_J.Biol.Chem_279_20501 Reaction mechanism of hydroxynitrile lyases of the alpha\/beta-hydrolase superfamily: the three-dimensional structure of the transient enzyme-substrate complex certifies the crucial role of LYS236
Mancheno_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_2107 Crystallization of a proteolyzed form of the horse pancreatic lipase-related protein 2: structural basis for the specific detergent requirement
Ota_2004_Nat.Genet_36_40 Complete sequencing and characterization of 21,243 full-length human cDNAs
Gerhard_2004_Genome.Res_14_2121 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)
Kim_2004_Mol.Pharm_1_117 A novel nucleoside prodrug-activating enzyme: substrate specificity of biphenyl hydrolase-like protein
Humphray_2004_Nature_429_369 DNA sequence and analysis of human chromosome 9
Dolinsky_2004_Cell.Mol.Life.Sci_61_1633 Triacylglycerol hydrolase: role in intracellular lipid metabolism
Martin_2004_Nature_432_988 The sequence and analysis of duplication-rich human chromosome 16
Marsh_2004_Genomics_84_661 Pharmacogenomic assessment of carboxylesterases 1 and 2
Sanghani_2004_Drug.Metab.Dispos_32_505 Hydrolysis of irinotecan and its oxidative metabolites, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino] carbonyloxycamptothecin and 7-ethyl-10-[4-(1-piperidino)-1-amino]-carbonyloxycamptothecin, by human carboxylesterases CES1A1, CES2, and a newly expressed carboxylesterase isoenzyme, CES3
Wu_2004_Pharmacogenet_14_595 Determination and analysis of single nucleotide polymorphisms and haplotype structure of the human carboxylesterase 2 gene
Charasson_2004_Clin.Pharmacol.Ther_76_528 Pharmacogenetics of human carboxylesterase 2, an enzyme involved in the activation of irinotecan into SN-38
Padmanabhan_2004_J.Biol.Chem_279_9615 The crystal structure of CCG1\/TAF(II)250-interacting factor B (CIB)
Knight_2004_Brain_127_1172 Dominantly inherited ataxia and dysphonia with dentate calcification: spinocerebellar ataxia type 20
Aertgeerts_2004_Protein.Sci_13_412 Crystal structure of human dipeptidyl peptidase IV in complex with a decapeptide reveals details on substrate specificity and tetrahedral intermediate formation
Bjelke_2004_J.Biol.Chem_279_34691 Tyrosine 547 constitutes an essential part of the catalytic mechanism of dipeptidyl peptidase IV
Hiramatsu_2004_Biol.Chem_385_561 The crystal structure of human dipeptidyl peptidase IV (DPPIV) complex with diprotin A
Peters_2004_Bioorg.Med.Chem.Lett_14_1491 Aminomethylpyrimidines as novel DPP-IV inhibitors: a 10(5)-fold activity increase by optimization of aromatic substituents
Weihofen_2004_J.Biol.Chem_279_43330 Crystal structure of CD26\/dipeptidyl-peptidase IV in complex with adenosine deaminase reveals a highly amphiphilic interface
Strop_2004_J.Mol.Biol_343_1055 Structure of a human A-type potassium channel interacting protein DPPX, a member of the dipeptidyl aminopeptidase family
Jerng_2004_Biophys.J_87_2380 Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)
Chen_2004_Protein.Expr.Purif_35_142 Purification and characterization of human prolyl dipeptidase DPP8 in Sf9 insect cells
Hosagrahara_2004_Chem.Biol.Interact_150_149 Functional analysis of human microsomal epoxide hydrolase genetic variants
Fornage_2004_Circulation_109_335 Polymorphism of the soluble epoxide hydrolase is associated with coronary artery calcification in African-American subjects: The Coronary Artery Risk Development in Young Adults (CARDIA) study
Gomez_2004_Biochemistry_43_4716 Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis
Dunham_2004_Nature_428_522 The DNA sequence and analysis of human chromosome 13
Chakravarty_2004_Proc.Natl.Acad.Sci.U.S.A_101_15567 Human fatty acid synthase: structure and substrate selectivity of the thioesterase domain
Kridel_2004_Cancer.Res_64_2070 Orlistat is a novel inhibitor of fatty acid synthase with antitumor activity
Beausoleil_2004_Proc.Natl.Acad.Sci.U.S.A_101_12130 Large-scale characterization of HeLa cell nuclear phosphoproteins
Deloukas_2004_Nature_429_375 The DNA sequence and comparative analysis of human chromosome 10
Kraemer_2004_Mol.Endocrinol_18_549 Hormone-sensitive lipase is required for high-density lipoprotein cholesteryl ester-supported adrenal steroidogenesis
Yeaman_2004_Biochem.J_379_11 Hormone-sensitive lipase--new roles for an old enzyme
Ben Ali_2004_Biochemistry_43_9298 Might the kinetic behavior of hormone-sensitive lipase reflect the absence of the lid domain?
Staege_2004_Cancer.Res_64_8213 DNA microarrays reveal relationship of Ewing family tumors to both endothelial and fetal neural crest-derived cells and define novel targets
Stein_2004_J.Biol.Chem_279_48930 NDRG1 is necessary for p53-dependent apoptosis
Cangul_2004_BMC.Genet_5_27 Hypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancers
Hirata_2004_Glia_47_325 N-myc downstream-regulated gene 1 expression in injured sciatic nerves
Sugiki_2004_Biol.Pharm.Bull_27_628 Association of N-myc downregulated gene 1 with heat-shock cognate protein 70 in mast cells
Sugiki_2004_Biol.Pharm.Bull_27_624 N-myc downregulated gene 1 is a phosphorylated protein in mast cells
Wang_2004_World.J.Gastroenterol_10_550 Correlation of N-myc downstream-regulated gene 1 overexpression with progressive growth of colorectal neoplasm
Mitchelmore_2004_Neurobiol.Dis_16_48 NDRG2: a novel Alzheimer's disease associated protein
Tanaka_2004_J.Biol.Chem_279_14256 Inositol deacylation of glycosylphosphatidylinositol-anchored proteins is mediated by mammalian PGAP1 and yeast Bst1p
Zhang_2004_Protein.Sci_13_2819 Signal peptide prediction based on analysis of experimentally verified cleavage sites
Sias_2004_Biochemistry_43_10138 Human pancreatic lipase-related protein 2 is a galactolipase
De Caro_2004_Biochim.Biophys.Acta_1701_89 Characterization of pancreatic lipase-related protein 2 isolated from human pancreatic juice
Shariat-Madar_2004_Blood_103_4554 Recombinant prolylcarboxypeptidase activates plasma prekallikrein
Collins_2004_Genome.Biol_5_R84 A genome annotation-driven approach to cloning the human ORFeome
Hou_2004_Proc.Natl.Acad.Sci.U.S.A_101_18036 Genome sequence of the deep-sea gamma-proteobacterium Idiomarina loihiensis reveals amino acid fermentation as a source of carbon and energy
Tomita_2004_Breed.Sci_54_0 Molecular characterization of a 313-kb genomic region containing the self-incompatibility locus of Ipomoea trifida, a diploid relative of sweet potato.
Chen_2004_Gene_337_189 Sequencing and analysis of the large virulence plasmid pLVPK of Klebsiella pneumoniae CG43
Choi_2004_Appl.Environ.Microbiol_70_3213 Characterization and heterologous gene expression of a novel esterase from Lactobacillus casei CL96
Pridmore_2004_Proc.Natl.Acad.Sci.U.S.A_101_2512 The genome sequence of the probiotic intestinal bacterium Lactobacillus johnsonii NCC 533
van der Kaaij_2004_Appl.Environ.Microbiol_70_1869 L-alanine auxotrophy of Lactobacillus johnsonii as demonstrated by physiological, genomic, and gene complementation approaches
Gatti_2004_J.Appl.Microbiol_96_223 Peptidase activity in various species of dairy thermophilic lactobacilli
Luo_2004_Proc.Natl.Acad.Sci.U.S.A_101_841 Multiple substrates of the Legionella pneumophila Dot\/Icm system identified by interbacterial protein transfer
Monteiro-Vitorello_2004_Mol.Plant.Microbe.Interact_17_827 The genome sequence of the gram-positive sugarcane pathogen Leifsonia xyli subsp. xyli
Nascimento_2004_J.Bacteriol_186_2164 Comparative genomics of two Leptospira interrogans serovars reveals novel insights into physiology and pathogenesis
Gardiner_2004_Mol.Microbiol_53_1307 The sirodesmin biosynthetic gene cluster of the plant pathogenic fungus Leptosphaeria maculans
Nelson_2004_Nucleic.Acids.Res_32_2386 Whole genome comparisons of serotype 4b and 1\/2a strains of the food-borne pathogen Listeria monocytogenes reveal new insights into the core genome components of this species
Borucki_2004_J.Clin.Microbiol_42_5270 Selective Discrimination of Listeria monocytogenes Epidemic Strains by a Mixed-Genome DNA Microarray Compared to Discrimination by Pulsed-Field Gel Electrophoresis, Ribotyping, and Multilocus Sequence Typing.
Heidari_2004_Insect.Biochem.Mol.Biol_34_353 Hydrolysis of organophosphorus insecticides by in vitro modified carboxylesterase E3 from Lucilia cuprina
Valenzuela_2004_J.Exp.Biol_207_3717 Identification of the most abundant secreted proteins from the salivary glands of the sand fly Lutzomyia longipalpis, vector of Leishmania chagasi
Stuhlfelder_2004_Eur.J.Biochem_271_2976 Cloning and expression of a tomato cDNA encoding a methyl jasmonate cleaving esterase
Zhu_2004_Insect.Biochem.Mol.Biol_34_1175 Enhanced esterase gene expression and activity in a malathion-resistant strain of the tarnished plant bug, Lygus lineolaris
Dorus_2004_Cell_119_1027 Accelerated evolution of nervous system genes in the origin of Homo sapiens
Cohen_2004_Biochem.J_378_117 Amino acid domains control the circulatory residence time of primate acetylcholinesterases in rhesus macaques (Macaca mulatta)
Maibeche-Coisne_2004_Chem.Senses_29_381 Putative odorant-degrading esterase cDNA from the moth Mamestra brassicae: cloning and expression patterns in male and female antennae
Stranzl_2004_J.Biol.Chem_279_3699 Observation of a short, strong hydrogen bond in the active site of hydroxynitrile lyase from Hevea brasiliensis explains a large pKa shift of the catalytic base induced by the reaction intermediate
Hong_2004_Nat.Biotechnol_22_1275 The genome sequence of the capnophilic rumen bacterium Mannheimia succiniciproducens
Ward_2004_PLoS.Biol_2_e303 Genomic insights into methanotrophy: the complete genome sequence of Methylococcus capsulatus (Bath)
Pearson_2004_Appl.Environ.Microbiol_70_6370 Inactivation of an ABC transporter gene, mcyH, results in loss of microcystin production in the cyanobacterium Microcystis aeruginosa PCC 7806
Raoult_2004_Science_306_1344 The 1.2-megabase genome sequence of Mimivirus
Ichiyama_2004_Biochim.Biophys.Acta_1698_27 Reactivity of asparagine residue at the active site of the D105N mutant of fluoroacetate dehalogenase from Moraxella sp. B
Farahani_2004_Obes.Res_12_292 Reciprocal hemizygosity analysis of mouse hepatic lipase reveals influence on obesity
Lian_2004_Am.J.Physiol.Lung.Cell.Mol.Physiol_286_L801 Lysosomal acid lipase deficiency causes respiratory inflammation and destruction in the lung
Okazaki_2004_DNA.Res_11_205 Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries
Subramanian_2004_J.Biol.Chem_279_42062 Perilipin A mediates the reversible binding of CGI-58 to lipid droplets in 3T3-L1 adipocytes
Bourne_2004_Proc.Natl.Acad.Sci.U.S.A_101_1449 Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation
Westin_2004_J.Biol.Chem_279_21841 Molecular cloning and characterization of two mouse peroxisome proliferator-activated receptor alpha (PPARalpha)-regulated peroxisomal acyl-CoA thioesterases
Furihata_2004_Drug.Metab.Dispos_32_1170 Identification of di-(2-ethylhexyl) phthalate-induced carboxylesterase 1 in C57BL\/6 mouse liver microsomes: purification, cDNA cloning, and baculovirus-mediated expression
Soni_2004_J.Biol.Chem_279_40683 Carboxylesterase 3 (EC 3.1.1.1) is a major adipocyte lipase
Stok_2004_J.Biol.Chem_279_29863 Identification, expression, and purification of a pyrethroid-hydrolyzing carboxylesterase from mouse liver microsomes
D'Agostino_2004_J.Nutr_134_132 Pancreatic lipase-related protein 2 is the major colipase-dependent pancreatic lipase in suckling mice
Shu_2004_Mol.Cell.Proteomics_3_279 Identification of phosphoproteins and their phosphorylation sites in the WEHI-231 B lymphoma cell line
Puente_2004_Genome.Res_14_609 A genomic analysis of rat proteases and protease inhibitors
Wang_2004_Endocrinology_145_5688 Expression of human hormone-sensitive lipase (HSL) in postmeiotic germ cells confers normal fertility to HSL-deficient mice
Fortier_2004_Am.J.Physiol.Endocrinol.Metab_287_E282 Hormone-sensitive lipase-independent adipocyte lipolysis during beta-adrenergic stimulation, fasting, and dietary fat loading
Peyot_2004_Diabetes_53_1733 Hormone-sensitive lipase has a role in lipid signaling for insulin secretion but is nonessential for the incretin action of glucagon-like peptide 1
Okuda_2004_Mol.Cell.Biol_24_3949 Ndrg1-deficient mice exhibit a progressive demyelinating disorder of peripheral nerves
Boyer_2004_Biol.Reprod_71_820 Pre-sertoli specific gene expression profiling reveals differential expression of Ppt1 and Brd3 genes within the mouse genital ridge at the time of sex determination
Taskin_2004_Genetika_40_1475 The genetic basis of malathion resistance in housefly (Musca domestica L.) strains from Turkey
Minion_2004_J.Bacteriol_186_7123 The genome sequence of Mycoplasma hyopneumoniae strain 232, the agent of swine mycoplasmosis
Jaffe_2004_Genome.Res_14_1447 The complete genome and proteome of Mycoplasma mobile
El-Etr_2004_Infect.Immun_72_6902 Identification of two Mycobacterium marinum loci that affect interactions with macrophages
Westberg_2004_Genome.Res_14_221 The genome sequence of Mycoplasma mycoides subsp. mycoides SC type strain PG1T, the causative agent of contagious bovine pleuropneumonia (CBPP)
Ronning_2004_J.Biol.Chem_279_36771 Mycobacterium tuberculosis antigen 85A and 85C structures confirm binding orientation and conserved substrate specificity
Wilson_2004_J.Mol.Biol_335_519 The structure of Mycobacterium tuberculosis MPT51 (FbpC1) defines a new family of non-catalytic alpha\/beta hydrolases
Chakhaiyar_2004_J.Infect.Dis_190_1237 Regions of high antigenicity within the hypothetical PPE major polymorphic tandem repeat open-reading frame, Rv2608, show a differential humoral response and a low T cell response in various categories of patients with tuberculosis
Canaan_2004_Eur.J.Biochem_271_3953 Expression and characterization of the protein Rv1399c from Mycobacterium tuberculosis. A novel carboxyl esterase structurally related to the HSL family
Rao_2004_Mol.Genet.Genomics_272_571 Interaction studies on proteins encoded by the phthiocerol dimycocerosate locus of Mycobacterium tuberculosis
Graziani_2004_Appl.Environ.Microbiol_70_2984 Novel polyketide synthase from Nectria haematococca
Kato_2004_Pestic.Biochem.Physiol_79_64 Comparison of kinetic properties of a hydrophilic form of acetylcholinesterase purified from strains susceptible and resistant to carbamate and organophosphorus insecticides of green rice leafhopper (Nephotettix cincticeps Uhler)
Schulze_2004_Anal.Chem_76_1720 Activation of phosphorothionate pesticides based on a cytochrome P450 BM-3 (CYP102 A1) mutant for expanded neurotoxin detection in food using acetylcholinesterase biosensors
Ferrer_2004_Appl.Environ.Microbiol_70_4499 Expression of a temperature-sensitive esterase in a novel chaperone-based Escherichia coli strain
Zagulski_2004_Curr.Biol_14_1397 High coding density on the largest Paramecium tetraurelia somatic chromosome
Horn_2004_Science_304_728 Illuminating the evolutionary history of chlamydiae
Osorio_2004_Biometals_17_725 Identification of Fur regulated genes in the bacterial fish pathogen Photobacterium damselae ssp. piscicida using the Fur titration assay
Chavez_2004_Biol.Res_37_107 The acetyl xylan esterase II gene from Penicillium purpurogenum is differentially expressed in several carbon sources, and tightly regulated by pH
Ast_2004_Arch.Microbiol_181_352 Phylogenetic analysis of the lux operon distinguishes two evolutionarily distinct clades of Photobacterium leiognathi
Futterer_2004_Proc.Natl.Acad.Sci.U.S.A_101_9091 Genome sequence of Picrophilus torridus and its implications for life around pH 0
Rea_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_1871 Expression, purification and preliminary crystallographic analysis of dipeptidyl peptidase IV from Porphyromonas gingivalis
Bruggemann_2004_Science_305_671 The complete genome sequence of Propionibacterium acnes, a commensal of human skin
Bocola_2004_Chembiochem_5_214 Learning from directed evolution: theoretical investigations into cooperative mutations in lipase enantioselectivity
Reetz_2004_Proc.Natl.Acad.Sci.U.S.A_101_5716 Controlling the enantioselectivity of enzymes by directed evolution: practical and theoretical ramifications
Ogino_2004_Mol.Genet.Genomics_271_189 Cloning, expression and characterization of a lipase gene (lip3) from Pseudomonas aeruginosa LST-03
Cheeseman_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_1237 Structure of an aryl esterase from Pseudomonas fluorescens
Komeda_2004_Eur.J.Biochem_271_1465 S-stereoselective piperazine-2-tert-butylcarboxamide hydrolase from Pseudomonas azotoformans IAM 1603 is a novel L-amino acid amidase
Chen_2004_FEMS.Microbiol.Lett_234_231 Polyhydroxyalkanoate synthases PhaC1 and PhaC2 from Pseudomonas stutzeri 1317 had different substrate specificities
Dogra_2004_J.Bacteriol_186_2225 Organization of lin genes and IS6100 among different strains of hexachlorocyclohexane-degrading Sphingomonas paucimobilis: evidence for horizontal gene transfer
Masai_2004_J.Bacteriol_186_2757 A novel tetrahydrofolate-dependent O-demethylase gene is essential for growth of Sphingomonas paucimobilis SYK-6 with syringate
Carl_2004_Gene_331_177 Sequence and transcriptional analysis of a gene cluster of Pseudomonas putida 86 involved in quinoline degradation
Couch_2004_J.Bacteriol_186_35 Characterization of CmaA, an adenylation-thiolation didomain enzyme involved in the biosynthesis of coronatine
Amrein_2004_Mol.Plant.Microbe.Interact_17_90 Functional analysis of genes involved in the synthesis of syringolin A by Pseudomonas syringae pv. syringae B301 D-R
Kulakova_2004_Biochim.Biophys.Acta_1696_59 Cold-active esterase from Psychrobacter sp. Ant300: gene cloning, characterization, and the effects of Gly-->Pro substitution near the active site on its catalytic activity and stability
Frick_2004_J.Biol.Chem_279_31131 Appropriate function of 11beta-hydroxysteroid dehydrogenase type 1 in the endoplasmic reticulum lumen is dependent on its N-terminal region sharing similar topological determinants with 50-kDa esterase
Gibbs_2004_Nature_428_493 Genome sequence of the Brown Norway rat yields insights into mammalian evolution
Hoffman_2004_Biochemistry_43_1496 Structural characterization of recombinant soluble rat neuroligin 1: mapping of secondary structure and glycosylation by mass spectrometry
Meyer_2004_Neuropharmacol_47_724 The complexity of PDZ domain-mediated interactions at glutamatergic synapses: a case study on neuroligin
Yamaguchi_2004_J.Biol.Chem_279_30490 CGI-58 interacts with perilipin and is localized to lipid droplets. Possible involvement of CGI-58 mislocalization in Chanarin-Dorfman syndrome
Stok_2004_Arch.Biochem.Biophys_430_247 Investigation of the role of a second conserved serine in carboxylesterases via site-directed mutagenesis
Wu_2004_Mol.Biol.Cell_15_2907 Organellar proteomics reveals Golgi arginine dimethylation
Maeda_2004_Gene_324_149 Genomic organization, expression, and comparative analysis of noncoding region of the rat Ndrg4 gene
Burchfield_2004_J.Biol.Chem_279_18623 Akt mediates insulin-stimulated phosphorylation of Ndrg2: evidence for cross-talk with protein kinase C theta
Hurt_2004_Genome.Res_14_631 The genomic sequence and comparative analysis of the rat major histocompatibility complex
Abe_2004_J.Biol.Chem_279_42605 Lysosomal phospholipase A2 is selectively expressed in alveolar macrophages
Streit_2004_J.Bacteriol_186_535 An evolutionary hot spot: the pNGR234b replicon of Rhizobium sp. strain NGR234
Taguchi_2004_Biosci.Biotechnol.Biochem_68_787 Multiplicity of 2,3-dihydroxybiphenyl dioxygenase genes in the Gram-positive polychlorinated biphenyl degrading bacterium Rhodococcus rhodochrous K37
Lee_2004_Enzyme.Microb.Technol_35_624 Production of (S)-styrene oxide by recombinant Pichia pastoris containing epoxide hydrolase from Rhodotorula glutinis
Larimer_2004_Nat.Biotechnol_22_55 Complete genome sequence of the metabolically versatile photosynthetic bacterium Rhodopseudomonas palustris
Portevin_2004_Proc.Natl.Acad.Sci.U.S.A_101_314 A polyketide synthase catalyzes the last condensation step of mycolic acid biosynthesis in mycobacteria and related organisms
Kim_2004_Appl.Environ.Microbiol_70_7086 Identification of a novel dioxygenase involved in metabolism of o-xylene, toluene, and ethylbenzene by Rhodococcus sp. strain DK17
Fournier_2004_J.Clin.Microbiol_42_5757 Use of highly variable intergenic spacer sequences for multispacer typing of Rickettsia conorii strains
McLeod_2004_J.Bacteriol_186_5842 Complete genome sequence of Rickettsia typhi and comparison with sequences of other rickettsiae
Eastmond_2004_J.Biol.Chem_279_45540 Cloning and characterization of the acid lipase from castor beans
Kodumal_2004_Proc.Natl.Acad.Sci.U.S.A_101_15573 Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster
McClelland_2004_Nat.Genet_36_1268 Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid
Hens_2004_Insect.Mol.Biol_13_615 Cyclorraphan yolk proteins and lepidopteran minor yolk proteins originate from two unrelated lipase families
Moran_2004_Nature_432_910 Genome sequence of Silicibacter pomeroyi reveals adaptations to the marine environment
Oakley_2004_Biochemistry_43_870 Crystal structure of haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26 at 0.95 A resolution: dynamics of catalytic residues
Holden_2004_Proc.Natl.Acad.Sci.U.S.A_101_9786 Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance
Li_2004_Curr.Microbiol_49_128 Cloning, function, and expression of sanS: a gene essential for nikkomycin biosynthesis of Streptomyces ansochromogenes
Ward_2004_Antimicrob.Agents.Chemother_48_4703 Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae
Otsuka_2004_Antimicrob.Agents.Chemother_48_3468 Cloning, sequencing, and functional analysis of an iterative type I polyketide synthase gene cluster for biosynthesis of the antitumor chlorinated polyenone neocarzilin in Streptomyces carzinostaticus
Ogasawara_2004_Chem.Biol_11_79 Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii
Noda_2004_J.Biol.Chem_279_46143 Self-protection mechanism in D-cycloserine-producing Streptomyces lavendulae. Gene cloning, characterization, and kinetics of its alanine racemase and D-alanyl-D-alanine ligase, which are target enzymes of D-cycloserine
Umezawa_2004_J.Biochem_136_293 Novel prolyl tri\/tetra-peptidyl aminopeptidase from Streptomyces mobaraensis: substrate specificity and enzyme gene cloning
Shah_2004_Microbiology_150_1947 A novel glucan-binding protein with lipase activity from the oral pathogen Streptococcus mutans
Banks_2004_J.Infect.Dis_190_727 Progress toward characterization of the group A Streptococcus metagenome: complete genome sequence of a macrolide-resistant serotype M6 strain
Tripathi_2004_Enzyme.Microb.Technol_34_437 Cloning, sequencing and structural features of a novel Streptococcus lipase
Ishiyama_2004_Appl.Environ.Microbiol_70_1297 Novel pathway of salicylate degradation by Streptomyces sp. strain WA46
Bolotin_2004_Nat.Biotechnol_22_1554 Complete sequence and comparative genome analysis of the dairy bacterium Streptococcus thermophilus
Schwartz_2004_Appl.Environ.Microbiol_70_7093 Biosynthetic gene cluster of the herbicide phosphinothricin tripeptide from Streptomyces viridochromogenes Tu494
Ejima_2004_J.Biosci.Bioeng_98_445 Molecular cloning and characterization of a thermostable carboxylesterase from an archaeon, Sulfolobus shibatae DSM5389: non-linear kinetic behavior of a hormone-sensitive lipase family enzyme
Suzuki_2004_FEMS.Microbiol.Lett_236_97 A novel thermostable esterase from the thermoacidophilic archaeon Sulfolobus tokodaii strain 7
Lei_2004_Anim.Genet_35_422 Sequence variation in the porcine lipoprotein lipase gene
Newman_2004_Endocrinology_145_5097 Cytochrome p450-dependent lipid metabolism in preovulatory follicles
Szeltner_2004_J.Mol.Biol_340_627 Concerted structural changes in the peptidase and the propeller domains of prolyl oligopeptidase are required for substrate binding
Piel_2004_J.Bacteriol_186_1280 Evidence for a symbiosis island involved in horizontal acquisition of pederin biosynthetic capabilities by the bacterial symbiont of Paederus fuscipes beetles
Ueda_2004_Nucleic.Acids.Res_32_4937 Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalism
Jaillon_2004_Nature_431_946 Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype
Armbrust_2004_Science_306_79 The genome of the diatom Thalassiosira pseudonana: ecology, evolution, and metabolism
Henne_2004_Nat.Biotechnol_22_547 The genome sequence of the extreme thermophile Thermus thermophilus
Dvir_2004_Embo.J_23_4394 The synaptic acetylcholinesterase tetramer assembles around a polyproline II helix
Greenblatt_2004_J.Am.Chem.Soc_126_15405 The complex of a bivalent derivative of galanthamine with torpedo acetylcholinesterase displays drastic deformation of the active-site gorge: implications for structure-based drug design
Seshadri_2004_Proc.Natl.Acad.Sci.U.S.A_101_5646 Comparison of the genome of the oral pathogen Treponema denticola with other spirochete genomes
Gao_2004_J.Clin.Microbiol_42_3298 Cloning and characterization of Trichophyton rubrum genes encoding actin, Tri r2, and Tri r4
Line_2004_J.Mol.Biol_338_519 The crystal structure of a (-) gamma-lactamase from an Aureobacterium species reveals a tetrahedral intermediate in the active site
Vedler_2004_J.Bacteriol_186_7161 The completely sequenced plasmid pEST4011 contains a novel IncP1 backbone and a catabolic transposon harboring tfd genes for 2,4-dichlorophenoxyacetic acid degradation
Liu_2004_Arch.Microbiol_181_287 Cloning, identification and expression of an entE homologue angE from Vibrio anguillarum serotype O1
Su_2004_Biochim.Biophys.Acta_1678_7 Cloning and characterization of the lipase and lipase activator protein from Vibrio vulnificus CKM-1
Koo_2004_J.Biol.Chem_279_31613 A novel fermentation\/respiration switch protein regulated by enzyme IIAGlc in Escherichia coli
Wu_2004_PLoS.Biol_2_E69 Phylogenomics of the reproductive parasite Wolbachia pipientis wMel: a streamlined genome overrun by mobile genetic elements
Royer_2004_Mol.Plant.Microbe.Interact_17_414 Albicidin pathotoxin produced by Xanthomonas albilineans is encoded by three large PKS and NRPS genes present in a gene cluster also containing several putative modifying, regulatory, and resistance genes
Mima_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_1622 Crystallization and preliminary X-ray analysis of carboxypeptidase Y inhibitor IC complexed with the cognate proteinase
Baxter_2004_Mol.Cell.Proteomics_3_209 Synergistic computational and experimental proteomics approaches for more accurate detection of active serine hydrolases in yeast
Bogomolnaya_2004_Curr.Genet_45_350 A new enrichment approach identifies genes that alter cell cycle progression in Saccharomyces cerevisiae
Aruna_2004_J.Biosci_29_33 Identification of a hypothetical membrane protein interactor of ribosomal phosphoprotein P0
Chain_2004_Proc.Natl.Acad.Sci.U.S.A_101_13826 Insights into the evolution of Yersinia pestis through whole-genome comparison with Yersinia pseudotuberculosis
Song_2004_DNA.Res_11_179 Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans
Collyn_2004_Infect.Immun_72_4784 YAPI, a new Yersinia pseudotuberculosis pathogenicity island
Zhou_2004_J.Bacteriol_186_5147 Genetics of metabolic variations between Yersinia pestis biovars and the proposal of a new biovar, microtus
Flieger_2004_Infect.Immun_72_2648 Cloning and characterization of the gene encoding the major cell-associated phospholipase A of Legionella pneumophila, plaB, exhibiting hemolytic activity
Suresh_2004_Int.J.Syst.Evol.Microbiol_54_1369 Bacillus indicus sp. nov., an arsenic-resistant bacterium isolated from an aquifer in West Bengal, India
Kim_2004_Int.J.Syst.Evol.Microbiol_54_2319 Kaistella koreensis gen. nov., sp. nov., a novel member of the Chryseobacterium-Bergeyella-Riemerella branch
Heidrich_2004_BMC.Pharmacol_4_5 Inhibition of pancreatic cholesterol esterase reduces cholesterol absorption in the hamster
Sugiyama_2004_Curr.Microbiol_48_424 Roles of poly(3-hydroxybutyrate) depolymerase and 3HB-oligomer hydrolase in bacterial PHB metabolism
DeJong_2004_J.Parasitol_90_991 The mitochondrial genome of Biomphalaria glabrata (Gastropoda: Basommatophora), intermediate host of Schistosoma mansoni
Gissi_2004_J.Mol.Evol_58_376 Complete mtDNA of Ciona intestinalis reveals extensive gene rearrangement and the presence of an atp8 and an extra trnM gene in ascidians
Watanabe_2004_Nature_429_382 DNA sequence and comparative analysis of chimpanzee chromosome 22
Mongin_2004_Trends.Parasitol_20_49 The Anopheles gambiae genome: an update
Matsuzaki_2004_Nature_428_653 Genome sequence of the ultrasmall unicellular red alga Cyanidioschyzon merolae 10D
Crepin_2004_Appl.Microbiol.Biotechnol_63_567 Identification of a type-D feruloyl esterase from Neurospora crassa
Hirsch_2004_Syst.Appl.Microbiol_27_166 Cryptoendolithic actinomycetes from antarctic sandstone rock samples: Micromonospora endolithica sp. nov. and two isolates related to Micromonospora coerulea Jensen 1932
Garcia-Conesa_2004_J.Biotechnol_108_227 The feruloyl esterase system of Talaromyces stipitatus: production of three discrete feruloyl esterases, including a novel enzyme, TsFaeC, with a broad substrate specificity
Cox_2004_Chem.Commun.(Camb)_2004_2260 Rapid cloning and expression of a fungal polyketide synthase gene involved in squalestatin biosynthesis
Ito_2004_Mol.Microbiol_52_399 Dissection of the host range of the fungal plant pathogen Alternaria alternata by modification of secondary metabolism
Takamatsu_2004_Mol.Microbiol_52_189 Genes in the accessory sec locus of Streptococcus gordonii have three functionally distinct effects on the expression of the platelet-binding protein GspB
Adler_2004_Muscle.Nerve_30_317 Reduced acetylcholine receptor density, morphological remodeling, and butyrylcholinesterase activity can sustain muscle function in acetylcholinesterase knockout mice
Boudinot_2004_Respir.Physiol.Neurobiol_140_231 Increased ventilation and CO2 chemosensitivity in acetylcholinesterase knockout mice
Chatonnet_2004_Adv.Exp.Med.Biol_551_165 Breathing without acetylcholinesterase
Bytyqi_2004_Eur.J.Neurosci_20_2953 Impaired formation of the inner retina in an AChE knockout mouse results in degeneration of all photoreceptors
Maekawa_2004_Clin.Chem_50_2410 Problem with detection of an insertion-type mutation in the BCHE gene in a patient with butyrylcholinesterase deficiency
Ordentlich_2004_Biochemistry_43_11255 Stereoselectivity toward VX is determined by interactions with residues of the acyl pocket as well as of the peripheral anionic site of AChE
Benting_2004_Pest.Manag.Sci_60_1051 Biochemical evidence that an S431F mutation in acetylcholinesterase-1 of Aphis gossypii mediates resistance to pirimicarb and omethoate
Andrews_2004_7th.ChE.Meeting.Pucon__229 A single amino acid substitution found in pirimicarb-insensitive acetylcholinesterase (AChE) of the peach-potato Aphid Myzus persicae (Sulz.)
Menozzi_2004_BMC.Evol.Biol_4_4 Mutations of acetylcholinesterase which confer insecticide resistance in Drosophila melanogaster populations
Shi_2004_BMC.Evol.Biol_4_5 Acetylcholinesterase alterations reveal the fitness cost of mutations conferring insecticide resistance
Kovarik_2004_Biochemistry_43_3222 Mutant cholinesterases possessing enhanced capacity for reactivation of their phosphonylated conjugates
Taskin_2004_Genetika_40_478 Determination of malathion and diazinon resistance by sequencing the Md alpha E7 gene from Guatemala, Colombia, Manhattan, and Thailand housefly (Musca domestica L.) strains
Park_2004_J.Biol.Chem_279_17085 The acetylcholinesterase homology region is essential for normal conformational maturation and secretion of thyroglobulin
Baryshev_2004_J.Mol.Endocrinol_32_903 Unfolded protein response is involved in the pathology of human congenital hypothyroid goiter and rat non-goitrous congenital hypothyroidism
Schopfer_2004_J.Med.Chem.Biol.Radiol.Def_2_1 Mutants of human butyrylcholinesterase with organophosphate hydrolase activity\; evidence that His117 is a general base catalyst for hydrolysis of echothiophate
Cusack_2004_7th.ChE.Meeting.Pucon__259 Tethering of ligands near the active site of acetylcholinesterase mutant H287C: Progress on a new strategy for protection against organophosphate inactivation
Hasin_2004_Hum.Mutat_24_408 A paradigm for single nucleotide polymorphism analysis: the case of the acetylcholinesterase gene
Muller_2004_Neuropediatrics_35_183 Synaptic congenital myasthenic syndrome in three patients due to a novel missense mutation (T441A) of the COLQ gene
Van Diepeningen_2004_Mycol.Res_108_919 Efficient degradation of tannic acid by black Aspergillus species
Robert_2004_J.Agric.Food.Chem_52_5102 Model studies on the formation of monochloropropanediols in the presence of lipase
Wang_2004_Appl.Environ.Microbiol_70_2367 Purification and characterization of a feruloyl esterase from the intestinal bacterium Lactobacillus acidophilus
Bostanian_2004_Pest.Manag.Sci_60_1231 The contact toxicity of indoxacarb and five other insecticides to Orius insidiosus (Hemiptera: Anthocoridae) and Aphidius colemani (Hymenoptera: Braconidae), beneficials used in the greenhouse industry
Eder_2004_Mar.Environ.Res_58_809 Molecular and cellular biomarker responses to pesticide exposure in juvenile chinook salmon (Oncorhynchus tshawytscha)
Horinouchi_2004_Biochem.Biophys.Res.Commun_324_597 Steroid degradation gene cluster of Comamonas testosteroni consisting of 18 putative genes from meta-cleavage enzyme gene tesB to regulator gene tesR
Coleman_2004_Neurosci_126_821 M2 muscarinic receptors in pontine reticular formation of C57BL\/6J mouse contribute to rapid eye movement sleep generation
Bernhard_2004_Naunyn.Schmiedebergs.Arch.Pharmacol_370_305 3H-Noradrenaline release from mouse iris-ciliary body: role of presynaptic muscarinic heteroreceptors
Banwell_2004_Neuromuscul.Disord_14_202 Novel truncating RAPSN mutations causing congenital myasthenic syndrome responsive to 3,4-diaminopyridine
Soukharev_2004_Anal.Biochem_327_140 A fluorogenic substrate for detection of organophosphatase activity
Walter_2004_Neurobiol.Aging_25_1299 Glycerophosphocholine is elevated in cerebrospinal fluid of Alzheimer patients
Zaccheo_2004_J.Biol.Chem_279_24024 Neuropathy target esterase and its yeast homologue degrade phosphatidylcholine to glycerophosphocholine in living cells
Cummins_2004_Plant.J_39_894 Purification and cloning of an esterase from the weed black-grass (Alopecurus myosuroides), which bioactivates aryloxyphenoxypropionate herbicides
Worek_2004_Arch.Toxicol_78_212 Reactivation and aging kinetics of human acetylcholinesterase inhibited by organophosphonylcholines
Komeda_2004_Eur.J.Biochem_271_1580 A novel R-stereoselective amidase from Pseudomonas sp. MCI3434 acting on piperazine-2-tert-butylcarboxamide
Jacobsen_2004_Food.Chem.Toxicol_42_1269 Repeated dose 28-day oral toxicity study in Wistar rats with a mixture of five pesticides often found as residues in food: alphacypermethrin, bromopropylate, carbendazim, chlorpyrifos and mancozeb
Nunes_2004_Chemosphere_57_1581 Acute and chronic effects of clofibrate and clofibric acid on the enzymes acetylcholinesterase, lactate dehydrogenase and catalase of the mosquitofish, Gambusia holbrooki
Kim_2004_Arch.Pharm.Res_27_1127 Acetylcholinesterase inhibitors from the aerial parts of Corydalis speciosa
Roivainen_2004_J.Nucl.Med_45_2032 Biodistribution and blood metabolism of 1-11C-methyl-4-piperidinyl n-butyrate in humans: an imaging agent for in vivo assessment of butyrylcholinesterase activity with PET
Kikuchi_2004_Bioorg.Med.Chem.Lett_14_1927 N-[18F]fluoroethylpiperidin-4-ylmethyl butyrate: a novel radiotracer for quantifying brain butyrylcholinesterase activity by positron emission tomography
Cokugras_2004_Protein.J_23_495 Do alkylating agents modify the histidine residue of the desensitized butyrylcholinesterase?
Sogorb_2004_Arch.Toxicol_78_629 Hydrolysis of carbaryl by human serum albumin
Matsuo_2004_Science_303_531 Role of LBPA and Alix in multivesicular liposome formation and endosome organization
Sohaskey_2004_FEMS.Microbiol.Lett_240_187 Enzymatic inactivation and reactivation of chloramphenicol by Mycobacterium tuberculosis and Mycobacterium bovis
Okamoto_2004_J.Agric.Food.Chem_52_5919 Degradation of malathion, in aqueous extracts of asparagus (Asparagus officinalis)
Fang_2004_Am.J.Physiol.Heart.Circ.Physiol_287_H2412 Effect of soluble epoxide hydrolase inhibition on epoxyeicosatrienoic acid metabolism in human blood vessels
Nagabukuro_2004_Eur.J.Pharmacol_485_299 Effects of TAK-802, a novel acetylcholinesterase inhibitor, on distension-induced rhythmic bladder contractions in rats and guinea pigs
Nagabukuro_2004_Eur.J.Pharmacol_494_225 Effects of TAK-802, a novel acetylcholinesterase inhibitor, and various cholinomimetics on the urodynamic characteristics in anesthetized guinea pigs
Sagiroglu_2004_Prep.Biochem.Biotechnol_34_169 Immobilization of lipases on different carriers and their use in synthesis of pentyl isovalerates
Viegas_2004_J.Nat.Prod_67_908 Further bioactive piperidine alkaloids from the flowers and green fruits of Cassia spectabilis
Molinar_2004_Tetrahedron.Asymmetry_15_1945 Enantioselective hydrolysis of (RS)-isopropylideneglycerol acetate with Kluyveromyces marxianus
Shao_2004_Bioorg.Med.Chem.Lett_14_4639 Synthesis and evaluation of tacrine-E2020 hybrids as acetylcholinesterase inhibitors for the treatment of Alzheimer's disease
Phyu_2004_Arch.Environ.Contam.Toxicol_46_308 Toxicity of atrazine and molinate to the cladoceran Daphnia carinata and the effect of river water and bottom sediment on their bioavailability
Qin_2004_J.Agric.Food.Chem_52_6239 Degradation and adsorption of fosthiazate in soil
Flematti_2004_Science_305_977 A compound from smoke that promotes seed germination
Aertgeerts_2004_Protein.Sci_13_145 N-linked glycosylation of dipeptidyl peptidase IV (CD26): effects on enzyme activity, homodimer formation, and adenosine deaminase binding
Pulinilkunnil_2004_J.Mol.Cell.Cardiol_37_931 Palmitoyl lysophosphatidylcholine mediated mobilization of LPL to the coronary luminal surface requires PKC activation
Sun_2004_J.Pharmacol.Exp.Ther_310_469 Methylphenidate is stereoselectively hydrolyzed by human carboxylesterase CES1A1
Morono_2004_Biotechnol.Lett_26_379 Application of glutaraldehyde for the staining of esterase-active cells with carboxyfluorescein diacetate
Peng_2004_Anal.Chem_76_5282 A three-dimensional flow control concept for single-cell experiments on a microchip. 2. Fluorescein diacetate metabolism and calcium mobilization in a single yeast cell as stimulated by glucose and pH changes
de Jong_2004_Bioorg.Med.Chem.Lett_14_1741 Carbazates as potent inhibitors of hormone-sensitive lipase
Lowe_2004_Bioorg.Med.Chem.Lett_14_3155 In vitro SAR of (5-(2H)-isoxazolonyl) ureas, potent inhibitors of hormone-sensitive lipase
Andoh_2004_Brain.Res_1013_125 PKC-independent inhibition of neuronal nicotinic acetylcholine receptors by diacylglycerol
Ghafouri_2004_Br.J.Pharmacol_143_774 Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2-arachidonoylglycerol
Hasler_2004_Psychopharmacology.(Berl)_172_145 Acute psychological and physiological effects of psilocybin in healthy humans: a double-blind, placebo-controlled dose-effect study
Nichols_2004_Pharmacol.Ther_101_131 Hallucinogens
Quistad_2004_Toxicol.Appl.Pharmacol_196_319 Lysophospholipase inhibition by organophosphorus toxicants
Casida_2004_Chem.Res.Toxicol_17_983 Organophosphate toxicology: safety aspects of nonacetylcholinesterase secondary targets
Kaphalia_2004_Toxicol.Appl.Pharmacol_200_7 Mechanism of differential inhibition of hepatic and pancreatic fatty acid ethyl ester synthase by inhibitors of serine-esterases: in vitro and cell culture studies
Carreiras_2004_Curr.Pharm.Des_10_3167 Recent approaches to novel anti-Alzheimer therapy
Youdim_2004_Neurotoxicol_25_243 Therapeutic applications of selective and non-selective inhibitors of monoamine oxidase A and B that do not cause significant tyramine potentiation
Li_2004_Rapid.Commun.Mass.Spectrom_18_651 A sensitive method for the determination of the novel cholinesterase inhibitor ZT-1 and its active metabolite huperzine A in rat blood using liquid chromatography\/tandem mass spectrometry
Manetsch_2004_J.Am.Chem.Soc_126_12809 In situ click chemistry: enzyme inhibitors made to their own specifications
Capsoni_2004_Am.J.Alzheimers.Dis.Other.Demen_19_153 Ganstigmine and donepezil improve neurodegeneration in AD11 antinerve growth factor transgenic mice
Mancini_2004_Org.Biomol.Chem_2_1368 Synthesis and bioactivity of linear oligomers related to polymeric alkylpyridinium metabolites from the Mediterranean sponge Reniera sarai
Suzuki_2004_J.Pestic.Sci_29_33 Effect of Long-Term Successive Applications of Organic Fertilizers on Dissipation of Several Pesticides in Two Soils
Maiza_2004_Commun.Agric.Appl.Biol.Sci_69_257 Reproductive effects in German cockroaches by ecdysteroid agonist RH-0345, juvenile hormone analogue methoprene and carbamate benfuracarb
Bogialli_2004_J.Chromatogr.A_1054_351 Simple and rapid assay for analyzing residues of carbamate insecticides in bovine milk: hot water extraction followed by liquid chromatography-mass spectrometry
Intorre_2004_Pharmacol.Res_49_171 Safety of azamethiphos in eel, seabass and trout
Fallang_2004_Pest.Manag.Sci_60_1163 Evidence for occurrence of an organophosphate-resistant type of acetylcholinesterase in strains of sea lice (Lepeophtheirus salmonis Kroyer)
Kristensen_2004_J.Econ.Entomol_97_1042 Susceptibility of spinosad in Musca domestica (Diptera: Muscidae) field populations
Rollinger_2004_J.Med.Chem_47_6248 Acetylcholinesterase inhibitory activity of scopolin and scopoletin discovered by virtual screening of natural products
Henderson_2004_Biochem.Pharmacol_68_959 S-oxygenation of the thioether organophosphate insecticides phorate and disulfoton by human lung flavin-containing monooxygenase 2
Muir_2004_Environ.Toxicol.Chem_23_2421 Empirical and modeling evidence of regional atmospheric transport of current-use pesticides
Buntin_2004_J.Econ.Entomol_97_374 Damage loss assessment and control of the cereal leaf beetle (Coleoptera: Chrysomelidae) in winter wheat
Smulders_2004_Toxicol.Sci_82_545 Block of neuronal nicotinic acetylcholine receptors by organophosphate insecticides
Fujino_2004_Chudoku.Kenkyu_17_273 [Three cases of organophosphate poisoning treated with pralidoxime iodide and whole-bowel irrigation]
Bolognesi_2004_J.Med.Chem_47_5945 Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues
McDaniel_2004_Neurotoxicol.Teratol_26_407 Differential profiles of cholinesterase inhibition and neurobehavioral effects in rats exposed to fenamiphos or profenofos
Wang_2004_Ecotoxicol.Environ.Saf_57_346 Separation, bioactivity, and dissipation of enantiomers of the organophosphorus insecticide fenamiphos
McKenney_2004_Arch.Environ.Contam.Toxicol_47_463 Comparative embryonic and larval developmental responses of estuarine shrimp (Palaemonetes pugio) to the juvenile hormone agonist fenoxycarb
Smulders_2004_Toxicol.Sci_82_219 A noncompetitive, sequential mechanism for inhibition of rat alpha4beta2 neuronal nicotinic acetylcholine receptors by carbamate pesticides
Heinrich_2004_J.Ethnopharmacol_92_147 Galanthamine from snowdrop--the development of a modern drug against Alzheimer's disease from local Caucasian knowledge
Roman_2004_Neuropharmacol_46_95 Potentiation effects of (+\/-)huprine X, a new acetylcholinesterase inhibitor, on nicotinic receptors in rat cortical synaptosomes
Shingyoji_2004_Cancer.Sci_95_537 In vitro conversion of irinotecan to SN-38 in human plasma
Jyothi_2004_J.Environ.Sci.Eng_46_274 Study of Serum Cholinesterase levels in fish Clarias batrachus (Linn.) exposed to pesticides carbaryl and phorate
Tada_2004_No.To.Shinkei_56_415 [A case of acute distigmine bromide intoxication in the therapeutic dosage for treatment of underactive neurogenic bladder]
Abdel-Rahman_2004_J.Toxicol.Environ.Health.A_67_163 Stress and combined exposure to low doses of pyridostigmine bromide, DEET, and permethrin produce neurochemical and neuropathological alterations in cerebral cortex, hippocampus, and cerebellum
Castro_2004_Heart_90_1119 Cholinergic stimulation with pyridostigmine protects against exercise induced myocardial ischaemia
Abou-Donia_2004_Pharmacol.Biochem.Behav_77_253 Co-exposure to pyridostigmine bromide, DEET, and\/or permethrin causes sensorimotor deficit and alterations in brain acetylcholinesterase activity
Husain_2004_Indian.J.Physiol.Pharmacol_48_150 Persistent\/delayed toxic effects of low-dose sarin and pyridostigmine under physical stress (exercise) in mice
Peden-Adams_2004_Immunopharmacol.Immunotoxicol_26_1 Pyridostigmine bromide (PYR) alters immune function in B6C3F1 mice
Soares_2004_Auton.Neurosci_113_24 Cholinergic stimulation with pyridostigmine increases heart rate variability and baroreflex sensitivity in rats
Taysse_2004_Cholinergic.Mechanisms.CRC.Press__729 Interaction between stress and pyridostigmine pretreatment in the mouse.
Telford_2004_Int.Immunopharmacol_4_1455 An in vitro investigation of the effects of the nerve agent pretreatment pyridostigmine bromide on human peripheral blood T-cell function
Song_2004_Toxicol.Sci_78_241 Interactive effects of paraoxon and pyridostigmine on blood-brain barrier integrity and cholinergic toxicity
Smith_2004_Cholinergic.Mechanisms.CRC.Press__711 Effect of pyridostigmine administration on acetylcholinesterase and choline acetyltransferase activity in guinea pig striatum and cerebellum.
Wang_2004_Nucl.Med.Biol_31_957 Facile synthesis and initial PET imaging of novel potential heart acetylcholinesterase imaging agents [11C]pyridostigmine and its analogs
Worek_2004_Biochem.Pharmacol_68_2237 Kinetic analysis of interactions between human acetylcholinesterase, structurally different organophosphorus compounds and oximes
Martin-Santamaria_2004_J.Med.Chem_47_4471 Modulation of binding strength in several classes of active site inhibitors of acetylcholinesterase studied by comparative binding energy analysis
Kassa_2004_Mil.Med.Sci.Lett_73_107 Pharmacological Prophylaxis and Antidotal Treatment of Acute Tabun Poisoning
Kassa_2004_Mil.Med.Sci.Lett_73_142 The Effect of Repeated Antidotal Treatment on Tabun-Induced Toxicity in Mice
Wobeser_2004_J.Wildl.Dis_40_163 Secondary poisoning of eagles following intentional poisoning of coyotes with anticholinesterase pesticides in western Canada
Liston_2004_Eur.J.Pharmacol_486_9 Pharmacology of selective acetylcholinesterase inhibitors: implications for use in Alzheimer's disease
Lee_2004_Nucl.Med.Commun_25_591 Synthesis and evaluation of 5,7-dihydro-3-[2-[1-(4-[18F]-fluorobenzyl)-4-piperidinyl]ethyl]-6H-pyrrolo[3,2-f] -1,2-benzisoxazol-6-one for in vivo mapping of acetylcholinesterase
Goldring_2004_Hepatology_39_1267 Activation of hepatic Nrf2 in vivo by acetaminophen in CD-1 mice
El-Merhibi_2004_Ecotoxicol.Environ.Saf_57_202 Role of piperonyl butoxide in the toxicity of chlorpyrifos to Ceriodaphnia dubia and Xenopus laevis
Gunning_2004_Cholinergic.Mechanisms.CRC.Press__581 Piperonyl butoxide.
McAbee_2004_Pest.Manag.Sci_60_359 Pyrethroid tolerance in Culex pipiens pipiens var molestus from Marin County, California
Natsuhara_2004_Pestic.Biochem.Physiol_79_33 Phenobarbital induction of permethrin detoxification and phenobarbital metabolism in susceptible and resistant strains of the beet armyworm Spodoptera exigua (Hubner)
Wadkins_2004_Mol.Pharmacol_65_1336 Discovery of novel selective inhibitors of human intestinal carboxylesterase for the amelioration of irinotecan-induced diarrhea: synthesis, quantitative structure-activity relationship analysis, and biological activity
Shinotoh_2004_Curr.Pharm.Des_10_1505 Acetylcholinesterase imaging: its use in therapy evaluation and drug design
Masson_2004_Eur.J.Biochem_271_1980 Rate-determining step of butyrylcholinesterase-catalyzed hydrolysis of benzoylcholine and benzoylthiocholine. Volumetric study of wild-type and D70G mutant behavior
Masson_2004_Eur.J.Biochem_271_220 Damped oscillatory hysteretic behaviour of butyrylcholinesterase with benzoylcholine as substrate
Estevez_2004_Toxicol.Lett_151_171 The inhibition of the high sensitive peripheral nerve soluble esterases by mipafox. A new mathematical processing for the kinetics of inhibition of esterases by organophosphorus compounds
Lozano_2004_Biotechnol.Prog_20_661 Criteria to design green enzymatic processes in ionic liquid\/supercritical carbon dioxide systems
Lichtman_2004_J.Pharmacol.Exp.Ther_311_441 Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: evidence for an unprecedented combination of potency and selectivity
Lee_2004_Biotechnol.Lett_26_1639 Isolation and characterization of Acinetobacter sp. ES-1 excreting a lipase with high enantioselectivity for (S)-ketoprofen ethyl ester
Liu_2004_J.Biotechnol_110_209 Integration of purification with immobilization of Candida rugosa lipase for kinetic resolution of racemic ketoprofen
Liu_2004_J.Ind.Microbiol.Biotechnol_31_495 Kinetic resolution of ketoprofen ester catalyzed by lipase from a mutant of CBS 5791
Kuca_2004_Acta.Medica.(Hradec.Kralove)_47_107 In vitro reactivation of acetylcholinesterase inhibited by cyclosarin using bisquaternary pyridinium aldoximes K005, K033, K027 AND K048
Kuca_2004_Acta.Medica.(Hradec.Kralove)_47_167 1,3-Bis(2-hydroxyiminomethylpyridinium) propane as the potential reactivator of the acetylcholinesterase inhibited by nerve agents
Kuca_2004_Cent.Eur.J.Public.Health_12 Suppl_S59 In vitro reactivation of tabun-inhibited acetylcholinesterase using new oximes--K027, K005, K033 and K048
Kuca_2004_Vet.Hum.Toxicol_46_15 In vitro reactivation of acetylcholinesterase using the oxime K027
Kuca_2004_Hum.Exp.Toxicol_23_167 Oximes-induced reactivation of rat brain acetylcholinesterase inhibited by VX agent
Kuca_2004_Pharmazie_59_795 A comparison of the efficacy of a bispyridinium oxime--1,4-bis-(2-hydroxyiminomethylpyridinium) butane dibromide and currently used oximes to reactivate sarin, tabun or cyclosarin-inhibited acetylcholinesterase by in vitro methods
Herkenhoff_2004_Arch.Toxicol_78_338 Effect of organophosphorus hydrolysing enzymes on obidoxime-induced reactivation of organophosphate-inhibited human acetylcholinesterase
Kovarik_2004_J.Enzyme.Inhib.Med.Chem_19_113 Interaction of human butyrylcholinesterase variants with bambuterol and terbutaline
Rhodes_2004_Toxicol.Appl.Pharmacol_195_203 Does pharmacotherapy for preterm labor sensitize the developing brain to environmental neurotoxicants? Cellular and synaptic effects of sequential exposure to terbutaline and chlorpyrifos in neonatal rats
Kim_2004_Anesth.Analg_99_1080 Tactile assessment for the reversibility of rocuronium-induced neuromuscular blockade during propofol or sevoflurane anesthesia
Kopman_2004_Anesth.Analg_98_102 Antagonism of cisatracurium and rocuronium block at a tactile train-of-four count of 2: should quantitative assessment of neuromuscular function be mandatory?
De Vriese_2004_Endocrinology_145_4997 Ghrelin degradation by serum and tissue homogenates: identification of the cleavage sites
Lopienska-Biernat_2004_Wiad.Parazytol_50_503 The activity of hydrolases of larval stages of Anisakis simplex (Nematoda)
Okuma_2004_J.Pestic.Sci_29_304 Plant Ion Channels as Potential Targets of Agro-Chemicals
Matsumura_2004_J.Pestic.Sci_29_299 Contemporary Issues on Pesticide Safety
Casida_2004_J.Pestic.Sci_29_81 Why Insecticides Are More Toxic to Insects than People: The Unique Toxicology of Insects
Kodaka_2004_J.Pestic.Sci_29_332 Aerobic Aquatic Soil Metabolism of Pesticides in Water- and Sediment-Spiked Systems
Ohno_2004_J.Pestic.Sci_29_96 Synthesis and Herbicidal Activity of New 1-Alkyl-3-aryloxypyrazole-4-carboxamide Derivatives
Ohno_2004_J.Pestic.Sci_29_15 Synthesis and Herbicidal Activity of New Pyrazole-4-carboxamide Derivatives
Mizutani_2004_J.Pestic.Sci_29_177 Residue Analysis of the Fungicide Benthiavalicarb-isopropyl and Its Degradation Products in Upland Field Soil
Tomizawa_2004_J.Pestic.Sci_29_177 Neonicotinoids and Derivatives: Effects in Mammalian Cells and Mice
Wakita_2004_J.Pestic.Sci_29_348 Synthesis and Structure-Activity Relationships of Dinotefuran Derivatives: Modification in the Nitroguanidine Part
Rossom_2004_Am.J.Geriatr.Pharmacother_2_303 Efficacy and tolerability of memantine in the treatment of dementia
Boyle_2004_Dement.Geriatr.Cogn.Disord_17_91 Treating apathy in Alzheimer's disease
Fagnani_2004_Dement.Geriatr.Cogn.Disord_17_5 Donepezil for the treatment of mild to moderate Alzheimer's disease in France: the economic implications
Heudorf_2004_Int.Arch.Occup.Environ.Health_77_67 Current internal exposure to pesticides in children and adolescents in Germany: urinary levels of metabolites of pyrethroid and organophosphorus insecticides
Khan_2004_Clin.Sci.(Lond)_106_183 Peripheral cholinergic function in humans with chronic fatigue syndrome, Gulf War syndrome and with illness following organophosphate exposure
Kim_2004_J.Appl.Physiol.(1985)_96_376 Acetylcholine release from the carotid body by hypoxia: evidence for the involvement of autoinhibitory receptors
Lutz_2004_J.Biol.Chem_279_238 Mice expressing only covalent dimeric heparin binding-deficient lipoprotein lipase: muscles inefficiently secrete dimeric enzyme
Pimlott_2004_Neuropsychopharmacology_29_108 Nicotinic acetylcholine receptor distribution in Alzheimer's disease, dementia with Lewy bodies, Parkinson's disease, and vascular dementia: in vitro binding study using 5-[(125)i]-a-85380
Sillanpaa_2004_Microbiology_150_2069 A family of putative MSCRAMMs from Enterococcus faecalis
Tse_2004_Chemosphere_54_41 Method for the determination of organophosphate insecticides in water, sediment and biota
Watt_2004_Am.J.Physiol.Endocrinol.Metab_286_E144 Glucose ingestion blunts hormone-sensitive lipase activity in contracting human skeletal muscle
Wynn_2004_Dement.Geriatr.Cogn.Disord_17_100 Cholinesterase inhibitor therapies and neuropsychiatric manifestations of Alzheimer's disease
Cheng_2004_Acta.Biochim.Biophys.Sin.(Shanghai)_36_211 Effects of Huangqi (Hex) on Inducing Cell Differentiation and Cell Death in K562 and HEL Cells
Abdel-Rahman_2004_J.Toxicol.Environ.Health.A_67_331 Neurological deficits induced by malathion, DEET, and permethrin, alone or in combination in adult rats
Abdel-Rahman_2004_Arch.Toxicol_78_467 Maternal exposure to nicotine and chlorpyrifos, alone and in combination, leads to persistently elevated expression of glial fibrillary acidic protein in the cerebellum of the offspring in late puberty
Abdollahi_2004_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_137_29 Oxidative stress and cholinesterase inhibition in saliva and plasma of rats following subchronic exposure to malathion
Abe_2004_J.Lipid.Res_45_667 Induction of lysosomal phospholipase A2 through the retinoid X receptor in THP-1 cells
Abel_2004_Toxicol.Sci_79_224 Biotransformation of methyl parathion by glutathione S-transferases
Abo-Elghar_2004_Pest.Manag.Sci_60_95 Persistence and residual activity of an organophosphate, pirimiphos-methyl, and three IGRs, hexaflumuron, teflubenzuron and pyriproxyfen, against the cowpea weevil, Callosobruchus maculatus (Coleoptera: Bruchidae)
Adams_2004_Drug.Chem.Toxicol_27_77 The application of the fluoride reactivation process to the detection of sarin and soman nerve agent exposures in biological samples
Agnew_2004_Evolution_58_579 Parasitism increases and decreases the costs of insecticide resistance in mosquitoes
Aharoni_2004_Proc.Natl.Acad.Sci.U.S.A_101_482 Directed evolution of mammalian paraoxonases PON1 and PON3 for bacterial expression and catalytic specialization
Ahn_2004_Chem.Commun.(Camb)__364 Probing lipase\/esterase libraries for lipid A hydrolases--discovery of biocatalysts for the detoxification of bacterially-expressed recombinant protein
Akaishi_2004_Arch.Environ.Contam.Toxicol_46_244 Morphological and neurotoxicological findings in tropical freshwater fish (Astyanax sp.) after waterborne and acute exposure to water soluble fraction (WSF) of crude oil
Akassoglou_2004_Proc.Natl.Acad.Sci.U.S.A_101_5075 Brain-specific deletion of neuropathy target esterase\/swisscheese results in neurodegeneration
Akiyama_2004_Am.J.Physiol.Regul.Integr.Comp.Physiol_287_R161 Effects of Ca2+ channel antagonists on acetylcholine and catecholamine releases in the in vivo rat adrenal medulla
Albers_2004_J.Occup.Environ.Med_46_367 The effects of occupational exposure to chlorpyrifos on the neurologic examination of central nervous system function: a prospective cohort study
Albers_2004_Muscle.Nerve_29_677 Absence of sensory neuropathy among workers with occupational exposure to chlorpyrifos
Albers_2004_Occup.Environ.Med_61_201 The effects of occupational exposure to chlorpyrifos on the peripheral nervous system: a prospective cohort study
Allert_2004_Proc.Natl.Acad.Sci.U.S.A_101_7907 Computational design of receptors for an organophosphate surrogate of the nerve agent soman
Almkvist_2004_Eur.J.Neurol_11_253 Preserved cognitive function after 12 months of treatment with rivastigmine in mild Alzheimer's disease in comparison with untreated AD and MCI patients
Altuntas_2004_Hum.Exp.Toxicol_23_9 The effects of diazinon on lipid peroxidation and antioxidant enzymes in erythrocytes in vitro
Amtage_2004_Brain.Res.Bull_62_413 Characterization of nicotinic receptors inducing noradrenaline release and absence of nicotinic autoreceptors in human neocortex
Anderson_2004_Curr.Treat.Options.Neurol_6_201 Dementia in Parkinson's Disease
Andreux_2004_Rev.Neurol.(Paris)_160_163 [Congenital myasthenic syndromes: phenotypic expression and pathophysiological characterisation]
Arias_2004_Neuropharmacol_46_103 Galantamine prevents apoptosis induced by beta-amyloid and thapsigargin: involvement of nicotinic acetylcholine receptors
Asari_2004_Vet.Hum.Toxicol_46_5 Changes in the hemodynamic state of patients with acute lethal organophosphate poisoning
Asha_2004_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_137_109 Combined effect of selenium and ascorbic acid on alcohol induced hyperlipidemia in male guinea pigs
Ashani_2004_Toxicol.Sci_77_358 Estimation of the upper limit of human butyrylcholinesterase dose required for protection against organophosphates toxicity: a mathematically based toxicokinetic model
Ashani_2004_Toxicol.Appl.Pharmacol_194_90 The effect of fluoride on the scavenging of organophosphates by human butyrylcholinesterase in buffer solutions and human plasma
Aucoin_2004_Biotechnol.Bioeng_85_647 Hyperactivation of Rhizomucor miehei lipase by hydrophobic xerogels
Augustus_2004_J.Biol.Chem_279_25050 Cardiac-specific knock-out of lipoprotein lipase alters plasma lipoprotein triglyceride metabolism and cardiac gene expression
Auta_2004_Neuropharmacol_46_397 Imidazenil: a potent and safe protective agent against diisopropyl fluorophosphate toxicity
Aygun_2004_Eur.J.Emerg.Med_11_55 Diagnosis in an acute organophosphate poisoning: report of three interesting cases and review of the literature
Aytac_2004_Curr.Drug.Targets.Immune.Endocr.Metabol.Disord_4_11 CD26\/dipeptidyl peptidase IV: a regulator of immune function and a potential molecular target for therapy
Azenabor_2004_Biol.Chem_385_67 Induction of lipoprotein lipase gene expression in Chlamydia pneumoniae-infected macrophages is dependent on Ca2+ signaling events
Azoulay_2004_Antimicrob.Agents.Chemother_48_104 Sensitive enzyme immunoassay for measuring plasma and intracellular nevirapine levels in human immunodeficiency virus-infected patients
Babaoglu_2004_Eur.J.Clin.Pharmacol_59_875 Frequency and enzyme activity of the butyrylcholinesterase K-variant in a Turkish population
Bain_2004_Environ.Toxicol.Chem_23_109 Effects of sublethal fenitrothion ingestion on cholinesterase inhibition, standard metabolism, thermal preference, and prey-capture ability in the Australian central bearded dragon (Pogona vitticeps, Agamidae)
Bania_2004_Acad.Emerg.Med_11_335 Jimson weed extract as a protective agent in severe organophosphate toxicity
Barata_2004_Aquat.Toxicol_66_125 Role of B-esterases in assessing toxicity of organophosphorus (chlorpyrifos, malathion) and carbamate (carbofuran) pesticides to Daphnia magna
Barros_2004_Environ.Toxicol.Chem_23_883 Determination of optimized protocols for the extraction of anticholinesterasic compounds in environmental samples containing cyanobacteria species
Bartolini_2004_J.Chromatogr.A_1031_27 Monolithic micro-immobilized-enzyme reactor with human recombinant acetylcholinesterase for on-line inhibition studies
Batulevicius_2004_Medicina.(Kaunas)_40_253 Key anatomic data for the use of rat heart in electrophysiological studies of the intracardiac nervous system
Beebe_2004_Bioorg.Med.Chem.Lett_14_2417 Synthesis and antibacterial activity of 6-O-arylpropargyl-9-oxime-11,12-carbamate ketolides
Belbeoc'h_2004_Eur.J.Biochem_271_1476 Elements of the C-terminal t peptide of acetylcholinesterase that determine amphiphilicity, homomeric and heteromeric associations, secretion and degradation
Bengtsson-Ellmark_2004_Eur.J.Hum.Genet_12_627 Association between a polymorphism in the carboxyl ester lipase gene and serum cholesterol profile
Benslama_2004_Ann.Fr.Anesth.Reanim_23_353 [The intermediate syndrome during organophosphorus pesticide poisoning]
Beracochea_2004_Psychopharmacology.(Berl)_176_66 BetaCCM but not physostigmine enhancement of memory retrieval depends on emotional processes in mice
Betancourt_2004_Toxicol.Sci_77_63 The effect of chlorpyrifos and chlorpyrifos-oxon on brain cholinesterase, muscarinic receptor binding, and neurotrophin levels in rats following early postnatal exposure
Bhakdi_2004_Circulation_109_1870 Possible protective role for C-reactive protein in atherogenesis: complement activation by modified lipoproteins halts before detrimental terminal sequence
Bhattacharya_2004_J.Org.Chem_69_559 Evidence of enhanced reactivity of DAAP nucleophiles toward dephosphorylation and deacylation reactions in cationic gemini micellar media
Bicker_2004_J.Chromatogr.A_1035_37 Direct high-performance liquid chromatographic method for enantioselective and diastereoselective determination of selected pyrethroic acids
Birk_2004_Pediatr.Res_55_921 Regulation of pancreatic lipase by dietary medium chain triglycerides in the weanling rat
Birk_2004_Pediatr.Res_56_256 Pancreatic lipase and its related protein 2 are regulated by dietary polyunsaturated fat during the postnatal development of rats
Birks_2004_Cochrane.Database.Syst.Rev__CD004748 Velnacrine for Alzheimer's disease
Blain_2004_Neurobiol.Dis_15_510 A role for lipoprotein lipase during synaptic remodeling in the adult mouse brain
Blaizot_2004_Cereb.Cortex_14_231 The parahippocampal gyrus in the baboon: anatomical, cytoarchitectonic and magnetic resonance imaging (MRI) studies
Bogialli_2004_J.Agric.Food.Chem_52_665 A simple and rapid assay for analyzing residues of carbamate insecticides in vegetables and fruits: hot water extraction followed by liquid chromatography-mass spectrometry
Bon_2004_Eur.J.Biochem_271_33 The C-terminal t peptide of acetylcholinesterase forms an alpha helix that supports homomeric and heteromeric interactions
Bond_2004_Med.Vet.Entomol_18_50 The naturally derived insecticide spinosad is highly toxic to Aedes and Anopheles mosquito larvae
Bos_2004_Diabetes.Care_27_796 The relationship of lipoprotein lipase activity and LDL size is dependent on glucose metabolism in an elderly population: the Hoorn Study
Boucher_2004_J.Lipid.Res_45_849 Apolipoprotein A-II regulates HDL stability and affects hepatic lipase association and activity
Boyd_2004_J.Biol.Chem_279_26612 Nanosecond dynamics of acetylcholinesterase near the active center gorge
Breuer_2004_J.Comp.Neurol_475_47 Development of neuromuscular junctions in the mouse esophagus: morphology suggests a role for enteric coinnervation during maturation of vagal myoneural contacts
Broedl_2004_Circ.Res_94_1554 Endothelial lipase promotes the catabolism of ApoB-containing lipoproteins
Brown_2004_Mar.Environ.Res_57_155 Characterisation of choline esterases and their tissue and subcellular distribution in mussel (Mytilus edulis)
Brun_2004_Environ.Sci.Technol_38_1115 Assessment of novel diazinon immunoassays for water analysis
Bruno_2004_Appl.Biochem.Biotechnol_113-116_189 Ester synthesis catalyzed by Mucor miehei lipase immobilized on magnetic polysiloxane-polyvinyl alcohol particles
Buchwalter_2004_Aquat.Toxicol_66_149 Roles of uptake, biotransformation, and target site sensitivity in determining the differential toxicity of chlorpyrifos to second to fourth instar Chironomous riparius (Meigen)
Buckley_2004_Int.J.Biochem.Cell.Biol_36_1281 The purification and characterisation of novel dipeptidyl peptidase IV-like activity from bovine serum
Bullock_2004_CNS.Drugs_18_79 Cholinesterase inhibitors and vascular dementia: another string to their bow?
Bullock_2004_Expert.Opin.Investig.Drugs_13_303 Future directions in the treatment of Alzheimer's disease
Burns_2004_Int.J.Geriatr.Psychiatry_19_243 Efficacy of rivastigmine in subjects with moderately severe Alzheimer's disease
Burton_2004_Drugs.Aging_21_229 Anaesthesia in elderly patients with neurodegenerative disorders: special considerations
Busek_2004_Int.J.Biochem.Cell.Biol_36_408 Dipeptidyl peptidase IV activity and\/or structure homologues (DASH) and their substrates in cancer
Butler_2004_Nat.Prod.Rep_21_180 The role of vanadium bromoperoxidase in the biosynthesis of halogenated marine natural products
Cai_2004_Diabetes_53_1369 Genome-wide scans reveal quantitative trait Loci on 8p and 13q related to insulin action and glucose metabolism: the San Antonio Family Heart Study
Calado_2004_J.Biotechnol_109_147 Integration of the production and the purification processes of cutinase secreted by a recombinant Saccharomyces cerevisiae SU50 strain
Calvert_2004_Am.Fam.Physician_69_1613 Health effects from pesticide exposure
Camarota_2004_J.Biol.Chem_279_27599 Carboxyl ester lipase cofractionates with scavenger receptor BI in hepatocyte lipid rafts and enhances selective uptake and hydrolysis of cholesteryl esters from HDL3
Campbell_2004_Chemosphere_54_1155 Persistence of carbofuran in marine sand and water
Carageorgiou_2004_Basic.Clin.Pharmacol.Toxicol_94_112 In vivo and in vitro effects of cadmium on adult rat brain total antioxidant status, acetylcholinesterase, (Na+, K+)-ATPase and Mg2+-ATPase activities: protection by L-cysteine
Carlton_2004_J.Community.Health_29_231 Pesticide sales in low-income, minority neighborhoods
Caughlan_2004_Toxicol.Sci_78_125 Chlorpyrifos induces apoptosis in rat cortical neurons that is regulated by a balance between p38 and ERK\/JNK MAP kinases
Cavallotti_2004_Lung_182_27 Cholinergic innervation of BALT (bronchus associated lymphoid tissue) in rat
Ceron_2004_Vet.J_167_294 The effects of different anticoagulants on routine canine plasma biochemistry
Chaize_2004_Artif.Cells.Blood.Substit.Immobil.Biotechnol_32_67 Encapsulation of enzymes in liposomes: high encapsulation efficiency and control of substrate permeability
Chambers_2004_Toxicol.Sci_77_185 Organophosphates, serine esterase inhibition, and modeling of organophosphate toxicity
Chan_2004_Neuropharmacol_46_1184 Differential contributions of NOS isoforms in the rostral ventrolateral medulla to cardiovascular responses associated with mevinphos intoxication in the rat
Chen_2004_Neurosci_125_141 Activation of muscarinic receptors inhibits spinal dorsal horn projection neurons: role of GABAB receptors
Cheon_2004_Bioorg.Med.Chem.Lett_14_2661 Lead discovery of quinoxalinediones as an inhibitor of dipeptidyl peptidase-IV (DPP-IV) by high-throughput screening
Chernock_2004_Hear.Res_188_12 A periodic network of neurochemical modules in the inferior colliculus
Chez_2004_J.Child.Neurol_19_165 Treating autistic spectrum disorders in children: utility of the cholinesterase inhibitor rivastigmine tartrate
Chou_2004_Biochem.Biophys.Res.Commun_319_433 Insights from modelling the 3D structure of the extracellular domain of alpha7 nicotinic acetylcholine receptor
Chowdhary_2004_Hypertension_43_1023 Nitric oxide and cardiac muscarinic control in humans
Cilingiroglu_2004_Curr.Atheroscler.Rep_6_126 Endothelial lipase and cholesterol metabolism
Cole_2004_Toxicol.Appl.Pharmacol_194_248 The nematode Caenorhabditis elegans as a model of organophosphate-induced mammalian neurotoxicity
Corbel_2004_Pest.Manag.Sci_60_375 Efficacy of insecticide mixtures against larvae of Culex quinquefasciatus (Say) (Diptera: Culicidae) resistant to pyrethroids and carbamates
Cormack_2004_Int.J.Geriatr.Psychiatry_19_371 Pentagon drawing and neuropsychological performance in Dementia with Lewy Bodies, Alzheimer's disease, Parkinson's disease and Parkinson's disease with dementia
Coronado_2004_Environ.Health.Perspect_112_142 Agricultural task and exposure to organophosphate pesticides among farmworkers
Cummings_2004_Am.J.Psychiatry_161_532 Reduction of behavioral disturbances and caregiver distress by galantamine in patients with Alzheimer's disease
Dai_2004_Zhonghua.Lao.Dong.Wei.Sheng.Zhi.Ye.Bing.Za.Zhi_22_11 [Protective effect of memantine on N-methyl-D-aspartate receptor in dichlorvos-poisoned rat brain]
Dajas-Bailador_2004_Trends.Pharmacol.Sci_25_317 Nicotinic acetylcholine receptors and the regulation of neuronal signalling
Daniel-Mwambete_2004_Int.J.Pharm_272_29 The effect of solubilization on the oral bioavailability of three benzimidazole carbamate drugs
Darreh-Shori_2004_J.Neurochem_88_1102 Long-lasting acetylcholinesterase splice variations in anticholinesterase-treated Alzheimer's disease patients
Darvesh_2004_Clin.Biochem_37_42 Differential effects of lipid-lowering agents on human cholinesterases
Day_2004_Exp.Brain.Res_155_500 Bioactivity of a peptide derived from acetylcholinesterase in hippocampal organotypic cultures
de Andrade_2004_Clin.Genet_65_390 Association between -250G\/A polymorphism of the hepatic lipase gene promoter and coronary artery disease and HDL-C levels in a Southern Brazilian population
De Giorgio_2004_IDrugs_7_160 Prokinetics in the treatment of acute intestinal pseudo-obstruction
De Sanctis_2004_Cell.Immunol_227_59 Lipoprotein lipase protects bovine endothelial cells from human NK cytotoxic activity
DeBalli_2004_JAMA_291_181 Treatment of sarin exposure
Degrace_2004_Mol.Cell.Biochem_258_171 Fatty acid oxidation and related gene expression in heart depleted of carnitine by mildronate treatment in the rat
Delgado_2004_Cad.Saude.Publica_20_180 [Pesticide use and poisoning among farmers from the county of Paty do Alferes, Rio de Janeiro, Brazil]
Demayo_2004_Pediatrics_113_e499 Grand mal seizure in a child 30 minutes after Cyclogyl (cyclopentolate hydrochloride) and 10\% Neo-Synephrine (phenylephrine hydrochloride) eye drops were instilled
Dengiz_2004_CNS.Spectr_9_377 The clinical efficacy and safety of galantamine in the treatment of Alzheimer's disease
Devi_2004_Pest.Manag.Sci_60_408 Esterase-mediated tolerance to a formulation of the organophosphate insecticide monocrotophos in the entomopathogenic fungus, Beauveria bassiana (Balsamo) Vuill: a promising biopesticide
Di Angelantonio_2004_Br.J.Pharmacol_141_644 Donepezil modulates nicotinic receptors of substantia nigra dopaminergic neurones
Di Lazzaro_2004_J.Neurol.Neurosurg.Psychiatry_75_555 Motor cortex hyperexcitability to transcranial magnetic stimulation in Alzheimer's disease
Di Luccio_2004_Appl.Biochem.Biotechnol_113-116_173 Effect of temperature, moisture, and carbon supplementation on lipase production by solid-state fermentation of soy cake by Penicillium simplicissimum
Domeneghini_2004_Histol.Histopathol_19_357 Cholinergic, nitrergic and peptidergic (Substance P- and CGRP-utilizing) innervation of the horse intestine. A histochemical and immunohistochemical study
Donsmark_2004_Biochem.Biophys.Res.Commun_316_867 Contractions induce phosphorylation of the AMPK site Ser565 in hormone-sensitive lipase in muscle
Drenhaus_2004_J.Comp.Neurol_468_496 Expression of axonin-1 in developing amacrine cells in the chick retina
Dutertre_2004_Eur.J.Biochem_271_2327 Computational approaches to understand alpha-conotoxin interactions at neuronal nicotinic receptors
Edwards_2004_Dement.Geriatr.Cogn.Disord_17 Suppl 1_40 Efficacy and safety of galantamine in patients with dementia with Lewy bodies: a 12-week interim analysis
Ehrich_2004_J.Toxicol.Environ.Health.A_67_431 Neurologic and immunologic effects of exposure to corticosterone, chlorpyrifos, and multiple doses of tri-ortho-tolyl phosphate over a 28-day period in rats
Eklund_2004_J.Biotechnol_109_277 Site-specific and reversible anchoring of active proteins onto cellulose using a cellulosome-like complex
Elgorashi_2004_Planta.Med_70_260 Acetylcholinesterase enzyme inhibitory effects of amaryllidaceae alkaloids
Emmett_2004_Neurosci.Lett_358_210 A peptide derived from the C-terminal region of acetylcholinesterase modulates extracellular concentrations of acetylcholinesterase in the rat substantia nigra
Enayetallah_2004_J.Histochem.Cytochem_52_447 Distribution of soluble epoxide hydrolase and of cytochrome P450 2C8, 2C9, and 2J2 in human tissues
Enz_2004_Biomed.Chromatogr_18_160 A simple, rapid and sensitive method for simultaneous determination of rivastigmine and its major metabolite NAP 226-90 in rat brain and plasma by reversed-phase liquid chromatography coupled to electrospray ionization mass spectrometry
Erhardt_2004_Eur.J.Neurosci_19_1773 Modulation of photic resetting in rats by lesions of projections to the suprachiasmatic nuclei expressing p75 neurotrophin receptor
Erkinjuntti_2004_Stroke_35_1010 Emerging therapies for vascular dementia and vascular cognitive impairment
Everett_2004_Exp.Neurol_185_290 Increased quantal size in transmission at slow but not fast neuromuscular synapses of apolipoprotein E deficient mice
Fahmy_2004_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_137_159 Esterase and lipase in camel tick Hyalomma dromedarii (Acari: Ixodidae) during embryogenesis
Fan_2004_J.Med.Genet_41_e28 Hepatic lipase C-480T polymorphism modifies the effect of HDL cholesterol on the risk of acute myocardial infarction in men: a prospective population based study
Faraj_2004_J.Lipid.Res_45_657 ASP enhances in situ lipoprotein lipase activity by increasing fatty acid trapping in adipocytes
Faraut_2004_Eur.J.Neurosci_19_2099 Thrombin reduces MuSK and acetylcholine receptor expression along with neuromuscular contact size in vitro
Feng_2004_Am.J.Hum.Genet_75_112 A common haplotype of the nicotine acetylcholine receptor alpha 4 subunit gene is associated with vulnerability to nicotine addiction in men
Ferguson_2004_Proc.Natl.Acad.Sci.U.S.A_101_8762 Lethal impairment of cholinergic neurotransmission in hemicholinium-3-sensitive choline transporter knockout mice
Ferrari_2004_Ecotoxicol.Environ.Saf_57_420 Time course of brain cholinesterase inhibition and recovery following acute and subacute azinphosmethyl, parathion and carbaryl exposure in the goldfish (Carassius auratus)
Ferreira_2004_J.Biotechnol_109_159 Recombinant Saccharomyces cerevisiae strain triggers acetate production to fuel biosynthetic pathways
Fickers_2004_J.Appl.Microbiol_96_742 Carbon and nitrogen sources modulate lipase production in the yeast Yarrowia lipolytica
Finucane_2004_Ann.Intern.Med_140_71 Alzheimer disease: current concepts and emerging diagnostic and therapeutic strategies
Fluckiger-Isler_2004_Mutat.Res_558_181 Assessment of the performance of the Ames II assay: a collaborative study with 19 coded compounds
Fodale_2004_Br.J.Anaesth_92_773 Different actions of sevoflurane and propofol on central nicotinic receptors may explain differences in hypnotic antagonism by cholinesterase inhibitors
Fodero_2004_J.Neurochem_88_1186 Alpha7-nicotinic acetylcholine receptors mediate an Abeta(1-42)-induced increase in the level of acetylcholinesterase in primary cortical neurones
Freeman_2004_J.Expo.Anal.Environ.Epidemiol_14_473 Seasonal pesticide use in a rural community on the US\/Mexico border
Freulet-Marriere_2004_Biochem.Biophys.Res.Commun_314_950 Rapid method for mean telomere length measurement directly from cell lysates
Friedman_2004_Psychopharmacology.(Berl)_174_45 Cholinergic targets for cognitive enhancement in schizophrenia: focus on cholinesterase inhibitors and muscarinic agonists
Fritz_2004_J.Colloid.Interface.Sci_275_642 Dependence of lipoprotein-lipase-catalyzed triacylglycerol hydrolysis on droplet size of synthetic monodisperse emulsions measured with static light scattering
Froelich_2004_Dement.Geriatr.Cogn.Disord_18_37 Donepezil for Alzheimer's disease in clinical practice--The DONALD Study. A multicenter 24-week clinical trial in Germany
Fruchart-Najib_2004_Biochem.Biophys.Res.Commun_319_397 Mechanism of triglyceride lowering in mice expressing human apolipoprotein A5
Fryer_2004_Am.J.Physiol.Lung.Cell.Mol.Physiol_286_L963 Mechanisms of organophosphate insecticide-induced airway hyperreactivity
Fuentes-Contreras_2004_Bull.Entomol.Res_94_11 Genetic diversity and insecticide resistance of Myzus persicae (Hemiptera: Aphididae) populations from tobacco in Chile: evidence for the existence of a single predominant clone
Fuh_2004_Int.J.Geriatr.Psychiatry_19_266 Measuring Alzheimer's disease progression with transition probabilities in the Taiwanese population
Fujii_2004_Nihon.Yakurigaku.Zasshi_123_179 [An independent, non-neuronal cholinergic system in lymphocytes and its roles in regulation of immune function]
Furnes_2004_Toxicol.Sci_78_196 Evaluation of xenobiotic N- and S-oxidation by variant flavin-containing monooxygenase 1 (FMO1) enzymes
Gabel_2004_Biophys.J_86_3152 The influence of solvent composition on global dynamics of human butyrylcholinesterase powders: a neutron-scattering study
Gais_2004_Proc.Natl.Acad.Sci.U.S.A_101_2140 Low acetylcholine during slow-wave sleep is critical for declarative memory consolidation
Gallarda_2004_Encephale_30_69 [Memantine (Ebixa): a new therapeutic strategy for the treatment of moderate to severe forms of Alzheimer's disease]
Galloway_2004_Environ.Sci.Technol_38_1723 A multibiomarker approach to environmental assessment
Galvez_2004_J.Invest.Surg_17_31 Evidence of secondary neuronal intestinal dysplasia in a rat model of chronic intestinal obstruction
Gambi_2004_J.Clin.Psychopharmacol_24_314 Alzheimer patients treated with an AchE inhibitor show higher IL-4 and lower IL-1 beta levels and expression in peripheral blood mononuclear cells
Gao_2004_J.Pharmacol.Exp.Ther_310_1046 An engineered cocaine hydrolase blunts and reverses cardiovascular responses to cocaine in rats
Gardner_2004_J.Am.Med.Dir.Assoc_5_101 Mirtazapine is associated with less anxiolytic use among elderly depressed patients in long-term care facilities
Gauster_2004_Biochem.J_382_75 Endothelial lipase-modified high-density lipoprotein exhibits diminished ability to mediate SR-BI (scavenger receptor B type I)-dependent free-cholesterol efflux
Gavala_2004_Biotechnol.Bioeng_85_561 Thermal and enzymatic pretreatment of sludge containing phthalate esters prior to mesophilic anaerobic digestion
Gentile_2004_Immunology_112_13 Thyroglobulin as an autoantigen: what can we learn about immunopathogenicity from the correlation of antigenic properties with protein structure?
Goodall_2004_Ann.Clin.Biochem_41_98 Cholinesterase: phenotyping and genotyping
Goodarzi_2004_Diabetes_53_214 Lipoprotein lipase is a gene for insulin resistance in Mexican Americans
Grafton-Cardwell_2004_J.Econ.Entomol_97_606 Role of esterase enzymes in monitoring for resistance of California red scale, Aonidiella aurantii (Homoptera: Diaspididae), to organophosphate and carbamate insecticides
Gsell_2004_Curr.Pharm.Des_10_265 Functional neurochemistry of Alzheimer's disease
Gu_2004_Eur.J.Neurosci_19_2123 Survival, regeneration and functional recovery of motoneurons in adult rats by reimplantation of ventral root following spinal root avulsion
Guan_2004_J.Cell.Biochem_92_53 Amino-terminal processing of MIP-1beta\/CCL4 by CD26\/dipeptidyl-peptidase IV
Guglielmone_2004_Med.Vet.Entomol_18_10 Abundance of stable flies on heifers treated for control of horn flies with organophosphate impregnated ear tags
Gunasekaran_2004_Chembiochem_5_224 Modulating functional loop movements: the role of highly conserved residues in the correlated loop motions
Guo_2004_Biotechnol.Prog_20_500 Characteristics of immobilized lipase on hydrophobic superparamagnetic microspheres to catalyze esterification
Gupta_2004_Appl.Microbiol.Biotechnol_64_763 Bacterial lipases: an overview of production, purification and biochemical properties
Gurnett_2004_J.Child.Neurol_19_175 Congenital myasthenic syndrome: presentation, electrodiagnosis, and muscle biopsy
Haiker_2004_Biochim.Biophys.Acta_1682_72 Rapid exchange of pancreatic lipase between triacylglycerol droplets
Han_2004_Zhonghua.Lao.Dong.Wei.Sheng.Zhi.Ye.Bing.Za.Zhi_22_69 [The clinical study of atropine application to the patients with organophosphate poisoning after treatment with plasma replacement]
Hansotia_2004_Diabetes_53_1326 Double incretin receptor knockout (DIRKO) mice reveal an essential role for the enteroinsular axis in transducing the glucoregulatory actions of DPP-IV inhibitors
Harrison_2004_J.Pharmacol.Exp.Ther_310_678 A guinea pig hippocampal slice model of organophosphate-induced seizure activity
Harrison_2004_Neurosci.Lett_357_183 Periodic orbit analysis reveals subtle effects of atropine on epileptiform activity in the guinea-pig hippocampal slice
Hatip-Al-Khatib_2004_Brain.Res_1012_169 Comparison of the effect of TAK-147 (zanapezil) and E-2020 (donepezil) on extracellular acetylcholine level and blood flow in the ventral hippocampus of freely moving rats
Haugen_2004_Endocrinology_145_3679 Retinoid X receptor gamma-deficient mice have increased skeletal muscle lipoprotein lipase activity and less weight gain when fed a high-fat diet
Hazel_2004_J.Exp.Biol_207_897 The substrate specificity of hormone-sensitive lipase from adipose tissue of the Antarctic fish Trematomus newnesi
Hedemann_2004_Arch.Anim.Nutr_58_47 Variations in enzyme activity in stomach and pancreatic tissue and digesta in piglets around weaning
Heo_2004_Dement.Geriatr.Cogn.Disord_17_151 Naringenin from Citrus junos has an inhibitory effect on acetylcholinesterase and a mitigating effect on amnesia
Herzog_2004_Oncogene_23_3033 Carcinogen-specific targeting of chromosome 12 for loss of heterozygosity in mouse lung adenocarcinomas: implications for chromosome instability and tumor progression
Hirano_2004_Metabolism_53_526 Measurement of the serum lipoprotein lipase concentration is useful for studying triglyceride metabolism: Comparison with postheparin plasma
Holstege_2004_Curr.Treat.Options.Neurol_6_17 Insecticides
Hoover_2004_Cardiovasc.Res_62_112 Localization of cholinergic innervation in guinea pig heart by immunohistochemistry for high-affinity choline transporters
Hotelier_2004_Nucleic.Acids.Res_32_D145 ESTHER, the database of the alpha\/beta-hydrolase fold superfamily of proteins
Hu_2004_Electrophoresis_25_512 Two-dimensional protein database of human pancreas
Hwang_2004_Biotechnol.Lett_26_603 Evaluation of cellulose-binding domain fused to a lipase for the lipase immobilization
Ibach_2004_Curr.Pharm.Des_10_231 Acetylcholinesterase inhibition in Alzheimer's Disease
Icenogle_2004_Neurotoxicol.Teratol_26_95 Behavioral alterations in adolescent and adult rats caused by a brief subtoxic exposure to chlorpyrifos during neurulation
Ichikawa_2004_Lab.Invest_84_715 Overexpression of lipoprotein lipase in transgenic rabbits leads to increased small dense LDL in plasma and promotes atherosclerosis
Isetun_2004_Anal.Bioanal.Chem_378_1847 Air sampling of organophosphate triesters using SPME under non-equilibrium conditions
Iwasa_2004_Nutrition_20_368 Efficacy of long-term dietary restriction of total calories, fat, iron, and protein in patients with chronic hepatitis C virus
Janowsky_2004_Pharmacol.Biochem.Behav_77_337 Antagonism of anticholinesterase (DFP) toxicity by donepezil plus scopolamine: a preliminary study
Janssen_2004_Curr.Opin.Chem.Biol_8_150 Evolving haloalkane dehalogenases
Jaye_2004_Curr.Opin.Lipidol_15_183 Endothelial lipase and HDL metabolism
Joaquim_2004_Am.J.Physiol.Heart.Circ.Physiol_287_H251 Enhanced heart rate variability and baroreflex index after stress and cholinesterase inhibition in mice
Johnson_2004_J.Cell.Biochem_91_999 Functional idiotypic mimicry of an adhesion- and differentiation-promoting site on acetylcholinesterase
Johnson_2004_J.Fam.Pract_53_181 Donepezil minimally effective for patients with vascular dementia
Justesen_2004_Tissue.Eng_10_381 Subcutaneous adipocytes can differentiate into bone-forming cells in vitro and in vivo
Kaieda_2004_Appl.Microbiol.Biotechnol_65_301 Enantioselective transesterification using immobilized Aspergillus oryzae overexpressing lipase
Kales_2004_N.Engl.J.Med_350_800 Acute chemical emergencies
Kalow_2004_Can.J.Anaesth_51_206 Atypical plasma cholinesterase. A personal discovery story: a tale of three cities
Kamanyire_2004_Occup.Med.(Lond)_54_69 Organophosphate toxicity and occupational exposure
Kamijima_2004_J.Occup.Health_46_109 A survey of semen indices in insecticide sprayers
Kang_2004_J.Am.Med.Dir.Assoc_5_167 Psychosis in nursing home patients with Parkinson's disease
Kang_2004_Toxicology_199_219 Chlropyrifos-methyl shows anti-androgenic activity without estrogenic activity in rats
Kaplan_2004_Biochemistry_43_3129 Is aromaticity essential for trapping the catalytic histidine 447 in human acetylcholinesterase?
Karanth_2004_Toxicol.Appl.Pharmacol_196_183 Interactive toxicity of the organophosphorus insecticides chlorpyrifos and methyl parathion in adult rats
Kasa_2004_Brain.Res_998_73 Effects of amyloid-beta on cholinergic and acetylcholinesterase-positive cells in cultured basal forebrain neurons of embryonic rat brain
Kassa_2004_Ceska.Slov.Farm_53_31 [Effect of acetylcholinesterase reactivator dosage on its effectiveness in the treatment of tabun poisoning in mice]
Kastrinsky_2004_J.Org.Chem_69_2284 Effective asymmetric synthesis of 1,2,9,9a-tetrahydrocyclopropa[c]benzo[e]indol-4-one (CBI)
Kaufer_2004_Dement.Geriatr.Cogn.Disord_17 Suppl 1_32 Pharmacologic treatment expectations in the management of dementia with Lewy bodies
Kaysen_2004_J.Am.Soc.Nephrol_15_538 The role of oxidative stress-altered lipoprotein structure and function and microinflammation on cardiovascular risk in patients with minor renal dysfunction
Kennedy_2004_Ann.Epidemiol_14_95 The specificity of the CDC-1994 criteria for chronic fatigue syndrome: comparison of health status in three groups of patients who fulfill the criteria
Kern_2004_J.Clin.Endocrinol.Metab_89_1352 Perilipin expression in human adipose tissue is elevated with obesity
Khalid_2004_Bioorg.Med.Chem_12_1995 Kinetics and structure-activity relationship studies on pregnane-type steroidal alkaloids that inhibit cholinesterases
Khovidhunkit_2004_J.Lipid.Res_45_1169 Effects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host
Kiens_2004_J.Appl.Physiol.(1985)_97_1209 Lipid-binding proteins and lipoprotein lipase activity in human skeletal muscle: influence of physical activity and gender
Kim_2004_J.Med.Chem_47_2110 Design, synthesis, and biological activity of 1,3-disubstituted ureas as potent inhibitors of the soluble epoxide hydrolase of increased water solubility
Kim_2004_Arch.Biochem.Biophys_425_33 Access to the carbamate tunnel of carbamoyl phosphate synthetase
Kim_2004_Mol.Cells_17_242 Carbofuran induces apoptosis of rat cortical neurons and down-regulates surface alpha7 subunit of acetylcholine receptors
Kimbell_2004_J.Biol.Chem_279_10997 C-terminal and heparin-binding domains of collagenic tail subunit are both essential for anchoring acetylcholinesterase at the synapse
Kishnani_2004_Arch.Neurol_61_605 Donepezil use in Down syndrome
Knaak_2004_Crit.Rev.Toxicol_34_143 Physicochemical and biological data for the development of predictive organophosphorus pesticide QSARs and PBPK\/PD models for human risk assessment
Kobayashi_2004_J.Pediatr.Surg_39_152 Inflammatory changes secondary to postoperative complications of Hirschsprung's disease as a cause of histopathologic changes typical of intestinal neuronal dysplasia
Kobayashi_2004_J.Atheroscler.Thromb_11_1 Pre-heparin lipoprotein lipase mass
Koch_2004_Curr.Pharm.Des_10_253 NMDA-antagonism (memantine): an alternative pharmacological therapeutic principle in Alzheimer's and vascular dementia
Kohila_2004_Arch.Toxicol_78_276 Evaluation of the effects of aluminium, ethanol and their combination on rat brain synaptosomal integral proteins in vitro and after 90-day oral exposure
Kojima_2004_Environ.Health.Perspect_112_524 Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells
Kok_2004_Biosens.Bioelectron_19_661 Determination of binary pesticide mixtures by an acetylcholinesterase-choline oxidase biosensor
Kompoliti_2004_J.Comp.Neurol_472_193 Effects of estrogen replacement therapy on cholinergic basal forebrain neurons and cortical cholinergic innervation in young and aged ovariectomized rhesus monkeys
Koutcherov_2004_Neuroreport_15_107 Organisation of the human dorsomedial hypothalamic nucleus
Kovar_2004_Physiol.Res_53_61 Hyperglycemia downregulates total lipoprotein lipase activity in humans
Krejcova_2004_Acta.Medica.(Hradec.Kralove)_47_13 Anticholinergic drugs--functional antidotes for the treatment of tabun intoxication
Krivoy_2004_JAMA_291_181\; author reply 182 Treatment of sarin exposure
Kropp_2004_Biochemistry_43_3716 The mipafox-inhibited catalytic domain of human neuropathy target esterase ages by reversible proton loss
Kumar_2004_Neurol.India_52_128 Clinical characteristics of organophosphate-induced delayed polyneuropathy
Kusunoki_2004_Metabolism_53_260 Lipoprotein lipase activator NO-1886 improves fatty liver caused by high-fat feeding in streptozotocin-induced diabetic rats
Kwoun_2004_FEMS.Microbiol.Lett_235_349 Sequence-based approach to finding functional lipases from microbial genome databases
Laakso_2004_Curr.Opin.Lipidol_15_115 Gene variants, insulin resistance, and dyslipidaemia
Lai_2004_J.Biol.Chem_279_13383 Identification of the Jak\/Stat proteins as novel downstream targets of EphA4 signaling in muscle: implications in the regulation of acetylcholinesterase expression
Lajmanovich_2004_Bull.Environ.Contam.Toxicol_72_586 Levels of serum cholinesterase activity in the rococo toad (Bufo paracnemis) in agrosystems of Argentina
Lanza_2004_Appl.Biochem.Biotechnol_113-116_181 The effect of temperature, pressure, exposure time, and depressurization rate on lipase activity in SCCO2
Lathem_2004_J.Exp.Med_199_1077 Potentiation of C1 esterase inhibitor by StcE, a metalloprotease secreted by Escherichia coli O157:H7
Lee_2004_J.Biol.Chem_279_27098 Transcriptional regulation of acetylcholinesterase-associated collagen ColQ: differential expression in fast and slow twitch muscle fibers is driven by distinct promoters
Lee_2004_J.Lipid.Res_45_1132 The lipoprotein lipase S447X polymorphism and plasma lipids: interactions with APOE polymorphisms, smoking, and alcohol consumption
Lee_2004_Arch.Pharm.Res_27_53 Acetylcholinesterase inhibitors from the twigs of Vaccinium oldhami Miquel
Lee_2004_J.Lipid.Res_45_1266 Association of hepatic lipase with proteoglycans stimulates the production of proteoglycans in vivo and in vitro
Lei_2004_Biotechnol.Bioeng_85_706 Whole cell-enzyme hybrid amperometric biosensor for direct determination of organophosphorous nerve agents with p-nitrophenyl substituent
Leroi_2004_Int.J.Geriatr.Psychiatry_19_1 Randomized placebo-controlled trial of donepezil in cognitive impairment in Parkinson's disease
Lessinger_2004_Clin.Chem.Lab.Med_42_62 Determination of lipase catalytic activity in two reference materials: BCR 693 and BCR 694 by titrimetry at constant pH
Levario-Carrillo_2004_Chemosphere_55_1421 Relation between pesticide exposure and intrauterine growth retardation
Li_2004_Bioorg.Med.Chem.Lett_14_1585 1H NMR relaxation investigation of acetylcholinesterase inhibitors from huperzine A and derivative
Liao_2004_J.Cell.Sci_117_2917 Non-genomic regulation of transmitter release by retinoic acid at developing motoneurons in Xenopus cell culture
Linne_2004_Eur.J.Biochem_271_1536 Mutational analysis of a type II thioesterase associated with nonribosomal peptide synthesis
Liu_2004_World.J.Gastroenterol_10_1379 Evaluation of effect of hybrid bioartificial liver using end-stage liver disease model
Llinas-Brunet_2004_J.Med.Chem_47_1605 Structure-activity study on a novel series of macrocyclic inhibitors of the hepatitis C virus NS3 protease leading to the discovery of BILN 2061
Lo_2004_Chirality_16_267 Utilizing hydrolases of opposite enantiopreference for the preparation of both enantiomers of (1R,7aR)-(-)- and (1S,7aS)-(+)-3,6,7,7a-tetrahydro-1-hydroxy-7a-methyl-1H-inden-5(2H)-one
Lopez_2004_Biotechnol.Prog_20_65 Reactivity of pure Candida rugosa lipase isoenzymes (Lip1, Lip2, and Lip3) in aqueous and organic media. influence of the isoenzymatic profile on the lipase performance in organic media
Loughnan_2004_Eur.J.Biochem_271_2294 Physico-chemical characterization and synthesis of neuronally active alpha-conotoxins
Luckarift_2004_Nat.Biotechnol_22_211 Enzyme immobilization in a biomimetic silica support
Ludwig_2004_Biochem.Biophys.Res.Commun_313_223 3D structure of the CD26-ADA complex obtained by cryo-EM and single particle analysis
Lugaresi_2004_Exp.Gerontol_39_653 IL-4 in vitro production is upregulated in Alzheimer's disease patients treated with acetylcholinesterase inhibitors
Lundstedt_2004_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_137_331 Digestive enzymes and metabolic profile of Pseudoplatystoma corruscans (Teleostei: Siluriformes) in response to diet composition
Ma_2004_Nucl.Med.Biol_31_393 Sensitivity of [11C]N-methylpyrrolidinyl benzilate ([11C]NMPYB) to endogenous acetylcholine: PET imaging vs tissue sampling methods
Maccarrone_2004_Mol.Hum.Reprod_10_215 Mouse blastocysts release a lipid which activates anandamide hydrolase in intact uterus
Machicao_2004_Horm.Metab.Res_36_303 Association of the -514C-->T polymorphism in the hepatic lipase gene (LIPC) promoter with elevated fasting insulin concentrations, but not insulin resistance, in non-diabetic Germans
Maeda_2004_Neurosci.Res_48_305 Vesicular acetylcholine transporter can be a morphological marker for the reinnervation to muscle of regenerating motor axons
Magnin_2004_J.Med.Chem_47_2587 Synthesis of novel potent dipeptidyl peptidase IV inhibitors with enhanced chemical stability: interplay between the N-terminal amino acid alkyl side chain and the cyclopropyl group of alpha-aminoacyl-l-cis-4,5-methanoprolinenitrile-based inhibitors
Malouf_2004_Cochrane.Database.Syst.Rev__CD004395 Donepezil for vascular cognitive impairment
Maltz_2004_Neurobiol.Aging_25_475 Enhanced cutaneous vascular response in AD subjects under donepezil therapy
Mank-Seymour_2004_Biochim.Biophys.Acta_1636_40 Association between single-nucleotide polymorphisms in the endothelial lipase (LIPG) gene and high-density lipoprotein cholesterol levels
Marco_2004_Bioorg.Med.Chem_12_2199 Synthesis, biological evaluation and molecular modelling of diversely functionalized heterocyclic derivatives as inhibitors of acetylcholinesterase\/butyrylcholinesterase and modulators of Ca2+ channels and nicotinic receptors
Marsh_2004_Curr.Treat.Options.Neurol_6_181 Psychosis in Parkinson's Disease
Maruyama_2004_Org.Biomol.Chem_2_1239 Poly(ethylene glycol)-lipase complexes that are highly active and enantioselective in ionic liquids
Massant_2004_Biochem.Soc.Trans_32_306 Metabolic channelling of carbamoyl phosphate in the hyperthermophilic archaeon Pyrococcus furiosus: dynamic enzyme-enzyme interactions involved in the formation of the channelling complex
Masterman_2004_Clin.Geriatr.Med_20_59 Cholinesterase inhibitors in the treatment of Alzheimer's disease and related dementias
Mastihubova_2004_Carbohydr.Res_339_1353 Lipase-catalysed preparation of acetates of 4-nitrophenyl beta-D-xylopyranoside and their use in kinetic studies of acetyl migration
Mathus-Vliegen_2004_Aliment.Pharmacol.Ther_19_601 Lipase inhibition by orlistat: effects on gall-bladder kinetics and cholecystokinin release in obesity
McKeith_2004_Lancet.Neurol_3_19 Dementia with Lewy bodies
McKeith_2004_Parkinsonism.Relat.Disord_10 Suppl 1_S15 Dementia with Lewy bodies and Parkinson's disease
McKillop_2004_Acta.Paediatr_93_10 Characterization of the C-terminal region of molecular forms of human milk bile salt-stimulated lipase
McPartland_2004_Brain.Res.Brain.Res.Rev_45_18 Phylogenomic and chemotaxonomic analysis of the endocannabinoid system
Medina_2004_Methods.Mol.Biol_268_459 Differentiation of lactic acid bacteria strains by postelectrophoretic detection of esterases
Medina_2004_Methods.Mol.Biol_268_465 Determination of esterolytic and lipolytic activities of lactic acid bacteria
Meshorer_2004_J.Biol.Chem_279_29740 Combinatorial complexity of 5' alternative acetylcholinesterase transcripts and protein products
Meyer_2004_Environ.Health.Perspect_112_295 Critical periods for chlorpyrifos-induced developmental neurotoxicity: alterations in adenylyl cyclase signaling in adult rat brain regions after gestational or neonatal exposure
Meyer_2004_Environ.Health.Perspect_112_170 Developmental effects of chlorpyrifos extend beyond neurotoxicity: critical periods for immediate and delayed-onset effects on cardiac and hepatic cell signaling
Miles_2004_Diabetes_53_521 Systemic and forearm triglyceride metabolism: fate of lipoprotein lipase-generated glycerol and free fatty acids
Millard_2004_Eur.J.Biochem_271_2320 Structure-activity relationships of alpha-conotoxins targeting neuronal nicotinic acetylcholine receptors
Mills_2004_J.Pharm.Pharmacol_56_375 Inhibition of acetylcholinesterase by Tea Tree oil
Miranda_2004_Occup.Environ.Med_61_e4 Muscular strength and vibration thresholds during two years after acute poisoning with organophosphate insecticides
Mitchell_2004_Anal.Chem_76_1098 Acetylcholine and choline amperometric enzyme sensors characterized in vitro and in vivo
Mongkolthanaruk_2004_J.Gen.Appl.Microbiol_50_29 Growth and lipase production of a psychrotrophic Acinetobacter calcoaceticus in an MSG-containing medium
Moriguchi_2004_J.Pharmacol.Exp.Ther_310_933 Mechanism of action of galantamine on N-methyl-D-aspartate receptors in rat cortical neurons
Mueller_2004_Brain.Res_1011_156 The adult central nervous cholinergic system of a neurogenetic model animal, the zebrafish Danio rerio
Mukherjee_2004_Environ.Int_30_811 Heavy metal levels and esterase variations between metal-exposed and unexposed duckweed Lemna minor: field and laboratory studies
Mulder_2004_Diabetes_53_122 Inhibition of lipase activity and lipolysis in rat islets reduces insulin secretion
Murty_2004_Biotechnol.Lett_26_563 Hydrolysis of rice bran oil using an immobilized lipase from Candida rugosa in isooctane
Nahar_2004_J.Invertebr.Pathol_85_80 The extracellular constitutive production of chitin deacetylase in Metarhizium anisopliae: possible edge to entomopathogenic fungi in the biological control of insect pests
Nakamura_2004_Intern.Med_43_18 A guideline for the treatment of dementia in Japan
Neishabouri_2004_Toxicology_196_173 Evaluation of immunotoxicity induced by diazinon in C57bl\/6 mice
Nguyen_2004_Toxicol.Lett_147_201 Copper ions and hypochlorite are mainly responsible for oxidative inactivation of paraoxon-hydrolyzing activity in human high density lipoprotein
Nguyen_2004_Arch.Dermatol_140_327 Pemphigus vulgaris acantholysis ameliorated by cholinergic agonists
Niazi_2004_J.Clin.Anesth_16_40 Prolonged neuromuscular blockade as a result of malnutrition-induced pseudocholinesterase deficiency
Nicke_2004_Eur.J.Biochem_271_2293 Learning about structure and function of neuronal nicotinic acetylcholine receptors. Lessons from snails
Nicke_2004_Eur.J.Biochem_271_2305 Alpha-conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes
Nieto-Ceron_2004_Neurochem.Int_45_129 Molecular properties of acetylcholinesterase in mouse spleen
Nijholt_2004_Mol.Psychiatry_9_174 Stress-induced alternative splicing of acetylcholinesterase results in enhanced fear memory and long-term potentiation
Niu_2004_J.Physiol_558_225 Utilization of triacylglycerol-rich lipoproteins by the working rat heart: routes of uptake and metabolic fates
Notingher_2004_Skin.Res.Technol_10_113 Mid-infrared in vivo depth-profiling of topical chemicals on skin
Okada_2004_Atherosclerosis_172_195 Relationship of post-heparin hepatic and lipoprotein lipases to high density lipoprotein modulation in obese children
Olichney_2004_Phys.Med.Rehabil.Clin.N.Am_15_205 Clinical applications of cognitive event-related potentials in Alzheimer's disease
Orhan_2004_J.Ethnopharmacol_91_57 Acetylcholinesterase and butyrylcholinesterase inhibitory activity of some Turkish medicinal plants
Orozco_2004_J.Pharmacol.Exp.Ther_310_987 ITH4012 (ethyl 5-amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylat e), a novel acetylcholinesterase inhibitor with calcium promotor and neuroprotective properties
Pain_2004_Sci.Total.Environ_326_55 Mortality of globally threatened Sarus cranes Grus antigon from monocrotophos poisoning in India
Palomo_2004_Biotechnol.Prog_20_630 Purification, immobilization, and stabilization of a lipase from Bacillus thermocatenulatus by interfacial adsorption on hydrophobic supports
Paradis_2004_Neurobiol.Dis_15_312 Lipoprotein lipase and endothelial lipase expression in mouse brain: regional distribution and selective induction following kainic acid-induced lesion and focal cerebral ischemia
Paradis_2004_Brain.Res.Dev.Brain.Res_149_29 Requirement for enzymatically active lipoprotein lipase in neuronal differentiation: a site-directed mutagenesis study
Park_2004_Neuroreport_15_1339 Carbachol induces a form of long-term potentiation in lateral amygdala
Park_2004_Cancer.Res_64_2652 Acetylcholinesterase plays a pivotal role in apoptosome formation
Parmee_2004_Bioorg.Med.Chem.Lett_14_43 4-Amino cyclohexylglycine analogues as potent dipeptidyl peptidase IV inhibitors
Pasalic_2004_Clin.Chim.Acta_343_179 Missense mutation W86R in exon 3 of the lipoprotein lipase gene in a boy with chylomicronemia
Pelak_2004_Curr.Treat.Options.Neurol_6_75 Visual Hallucinations
Peng_2004_Acta.Pharmacol.Sin_25_15 Therapeutic efficacy of charcoal hemoperfusion in patients with acute severe dichlorvos poisoning
Pereira_2004_Appl.Biochem.Biotechnol_113-116_433 Enzymatic synthesis of monolaurin
Pereira_2004_Toxicol.Lett_146_269 2,5-Hexanedione inhibits rat brain acetylcholinesterase activity in vitro
Perreault_2004_Obes.Res_12_241 Gender differences in lipoprotein lipase activity after acute exercise
Pessah_2004_Bioorg.Med.Chem_12_1859 Bioactivation of carbamate-based 20(S)-camptothecin prodrugs
Petrikis_2004_Int.Clin.Psychopharmacol_19_49 Treatment of Huntington's disease with galantamine
Petroianu_2004_J.Appl.Toxicol_24_143 In vitro protection of plasma cholinesterases by metoclopramide from inhibition by mipafox
Phillips_2004_Environ.Toxicol.Chem_23_435 In situ water and sediment toxicity in an agricultural watershed
Phinney_2004_Eur.J.Neurosci_19_1731 Stereological analysis of the reorganization of the dentate gyrus following entorhinal cortex lesion in mice
Pisciotta_2004_Atherosclerosis_172_309 Familial HDL deficiency due to ABCA1 gene mutations with or without other genetic lipoprotein disorders
Pringle_2004_Plant.Physiol.Biochem_42_73 Purification of ENOD8 proteins from Medicago sativa root nodules and their characterization as esterases
Pruneta-Deloche_2004_J.Lipid.Res_45_859 Alteration in lipoprotein lipase activity bound to triglyceride-rich lipoproteins in the postprandial state in type 2 diabetes
Qi_2004_Clin.Genet_65_93 Genetic variation at the hormone sensitive lipase: gender-specific association with plasma lipid and glucose concentrations
Rahman_2004_Bull.Environ.Contam.Toxicol_72_38 In vitro acetylcholinesterase inhibition by novel OP compounds in various tissues of the fish Channa punctatus
Raskind_2004_Arch.Neurol_61_252 The cognitive benefits of galantamine are sustained for at least 36 months: a long-term extension trial
Rawlings_2004_Nucleic.Acids.Res_32_D160 MEROPS: the peptidase database
Reale_2004_J.Neuroimmunol_148_162 Treatment with an acetylcholinesterase inhibitor in Alzheimer patients modulates the expression and production of the pro-inflammatory and anti-inflammatory cytokines
Relyea_2004_Environ.Toxicol.Chem_23_1080 Synergistic impacts of malathion and predatory stress on six species of North American tadpoles
Ren_2004_Planta.Med_70_201 Novel diterpenoid acetylcholinesterase inhibitors from Salvia miltiorhiza
Resina_2004_J.Biotechnol_109_103 Expression of a Rhizopus oryzae lipase in Pichia pastoris under control of the nitrogen source-regulated formaldehyde dehydrogenase promoter
Richardson_2004_Toxicol.Sci_77_83 Neurochemical effects of repeated gestational exposure to chlorpyrifos in developing rats
Rickwood_2004_Aquat.Toxicol_67_45 Acetylcholinesterase inhibition as a biomarker of adverse effect. A study of Mytilus edulis exposed to the priority pollutant chlorfenvinphos
Rizos_2004_JOP_5_44 Carbofuran-induced acute pancreatitis
Rochu_2004_Biochem.J_380_627 Contribution of the active-site metal cation to the catalytic activity and to the conformational stability of phosphotriesterase: temperature- and pH-dependence
Rockwood_2004_Lancet.Neurol_3_119 Lending a helping eye: artists in residence at a memory clinic
Rockwood_2004_J.Neurol.Neurosurg.Psychiatry_75_677 Size of the treatment effect on cognition of cholinesterase inhibition in Alzheimer's disease
Rodriguez_2004_Clin.Neurophysiol_115_39 Quantitative EEG and perfusional single photon emission computed tomography correlation during long-term donepezil therapy in Alzheimer's disease
Rohrer_2004_Curr.Opin.Lipidol_15_269 High density lipoproteins in the intersection of diabetes mellitus, inflammation and cardiovascular disease
Roldan_2004_Rev.Neurol_38_591 [Neuropsychological sequelae of acute poisoning by pesticides containing cholinesterase inhibitors]
Roman_2004_Expert.Opin.Pharmacother_5_161 Donepezil: a clinical review of current and emerging indications
Rosenau_2004_Chembiochem_5_152 Lipase-specific foldases
Roy_2004_Brain.Res.Dev.Brain.Res_148_197 Morphologic effects of subtoxic neonatal chlorpyrifos exposure in developing rat brain: regionally selective alterations in neurons and glia
Rudberg_2004_J.Biol.Chem_279_27376 Leukotriene A4 hydrolase: identification of a common carboxylate recognition site for the epoxide hydrolase and aminopeptidase substrates
Ruel_2004_J.Lipid.Res_45_1528 Evidence that hepatic lipase deficiency in humans is not associated with proatherogenic changes in HDL composition and metabolism
Ruiz_2004_Biochim.Biophys.Acta_1672_184 Activation and inhibition of Candida rugosa and Bacillus-related lipases by saturated fatty acids, evaluated by a new colorimetric microassay
Saario_2004_Biochem.Pharmacol_67_1381 Monoglyceride lipase-like enzymatic activity is responsible for hydrolysis of 2-arachidonoylglycerol in rat cerebellar membranes
Sadik_2004_J.Chem.Inf.Comput.Sci_44_499 Detection and classification of organophosphate nerve agent simulants using support vector machines with multiarray sensors
Saisuburamaniyan_2004_Anal.Biochem_330_70 Lipase assay in soils by copper soap colorimetry
Sakurai_2004_Pharm.Res_21_285 Esterase-like activity of serum albumin: characterization of its structural chemistry using p-nitrophenyl esters as substrates
Sales_2004_Toxicology_195_187 Preliminary characterisation of an in vitro paradigm for the study of the delayed effects of organophosphorus compounds: hen embryo brain spheroids
Salminen_2004_Mol.Pharmacol_65_1526 Subunit composition and pharmacology of two classes of striatal presynaptic nicotinic acetylcholine receptors mediating dopamine release in mice
Sanchez-Santed_2004_Neurotoxicol.Teratol_26_305 Long-term functional neurotoxicity of paraoxon and chlorpyrifos: behavioural and pharmacological evidence
Santos_2004_Neurotoxicol_25_481 Spine density and dendritic branching pattern of hippocampal CA1 pyramidal neurons in neonatal rats chronically exposed to the organophosphate paraoxon
Sass_2004_Environ.Health.Perspect_112_A340 Human testing: Sass and Needleman respond to industry
Sawicka-Zukowska_2004_J.Appl.Genet_45_37 Intensification of lipase biosynthesis as a result of electrofusion of Rhizopus cohnii protoplasts
Sayer_2004_Clin.Biochem_37_98 Association of a salivary acetylcholinesterase with Alzheimer's disease and response to cholinesterase inhibitors
Schaap_2004_J.Biol.Chem_279_27941 ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis
Schallreuter_2004_Biochem.Biophys.Res.Commun_315_502 Activation\/deactivation of acetylcholinesterase by H2O2: more evidence for oxidative stress in vitiligo
Schier_2004_JAMA_291_182\; author reply 182 Treatment of sarin exposure
Schlade-Bartusiak_2004_Mutat.Res_558_121 Influence of GSTT1, mEH, CYP2E1 and RAD51 polymorphisms on diepoxybutane-induced SCE frequency in cultured human lymphocytes
Schmidt_2004_J.Neurobiol_59_114 Activity-driven sharpening of the retinotectal projection: the search for retrograde synaptic signaling pathways
Secundo_2004_Biotechnol.Bioeng_86_236 Activity and enantioselectivity of wildtype and lid mutated Candida rugosa lipase isoform 1 in organic solvents
Segura_2004_Biotechnol.Prog_20_825 Different properties of the lipases contained in porcine pancreatic lipase extracts as enantioselective biocatalysts
Selcen_2004_Neurology_62_1945 Are MuSK antibodies the primary cause of myasthenic symptoms?
Semenkovich_2004_Trends.Cardiovasc.Med_14_72 Fatty acid metabolism and vascular disease
Sen_2004_Biosens.Bioelectron_19_1261 Polyvinylferrocenium modified Pt electrode for the design of amperometric choline and acetylcholine enzyme electrodes
Serri_2004_J.Clin.Endocrinol.Metab_89_979 Enhanced lipoprotein lipase secretion and foam cell formation by macrophages of patients with growth hormone deficiency: possible contribution to increased risk of atherogenesis?
Shahdat_2004_Life.Sci_74_3009 Synaptic plasma membrane-bound acetylcholinesterase activity is not affected by docosahexaenoic acid-induced decrease in membrane order
Sharma_2004_Insect.Biochem.Mol.Biol_34_425 Proteomic analysis of brown planthopper: application to the study of carbamate toxicity
Sharp_2004_J.Pharmacol.Exp.Ther_309_1116 Effects of galantamine, a nicotinic allosteric potentiating ligand, on nicotine-induced catecholamine release in hippocampus and nucleus accumbens of rats
Siegler_2004_Clin.Pharmacol.Ther_75_484 Treatment of urinary incontinence with anticholinergics in patients taking cholinesterase inhibitors for dementia
Silva_2004_Toxicol.Lett_147_53 Methyl parathion interaction with human and bovine serum albumin
Simon_2004_Learn.Mem_11_116 Galantamine facilitates acquisition of a trace-conditioned eyeblink response in healthy, young rabbits
Sklan_2004_Proc.Natl.Acad.Sci.U.S.A_101_5512 Acetylcholinesterase\/paraoxonase genotype and expression predict anxiety scores in Health, Risk Factors, Exercise Training, and Genetics study
Slatkin_2004_J.Pain.Symptom.Manage_27_268 Treatment of opioid-induced delirium with acetylcholinesterase inhibitors: a case report
Slotkin_2004_Neurotoxicol_25_631 Guidelines for developmental neurotoxicity and their impact on organophosphate pesticides: a personal view from an academic perspective
Small_2004_Trends.Neurosci_27_245 Do acetylcholinesterase inhibitors boost synaptic scaling in Alzheimer's disease?
Soares_2004_Appl.Biochem.Biotechnol_113-116_307 Studies on immobilized lipase in hydrophobic sol-gel
Song_2004_Biophys.J_86_2017 Finite element solution of the steady-state Smoluchowski equation for rate constant calculations
Stacey_2004_QJM_97_75 Secondary contamination in organophosphate poisoning: analysis of an incident
Stahl_2004_Curr.Med.Res.Opin_20_517 Examination of nighttime sleep-related problems during double-blind, placebo-controlled trials of galantamine in patients with Alzheimer's disease
Stepanyan_2004_Chem.Senses_29_179 Primary culture of lobster (Homarus americanus) olfactory sensory neurons
Stojan_2004_Eur.J.Biochem_271_1364 Inhibition of Drosophila melanogaster acetylcholinesterase by high concentrations of substrate
Suh_2004_Drugs.Aging_21_395 Risk of antipsychotic drug use in patients with Alzheimer's disease treated with rivastigmine
Sultzer_2004_Dement.Geriatr.Cogn.Disord_17_78 Psychosis and antipsychotic medications in Alzheimer's disease: clinical management and research perspectives
Sun_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_954 Crystallization and preliminary X-ray studies of methyl parathion hydrolase from Pseudomonas sp. WBC-3
Sun_2004_Zhonghua.Lao.Dong.Wei.Sheng.Zhi.Ye.Bing.Za.Zhi_22_7 [Muscarine receptor gene expression in brain and peripheral blood lymphocytes of rats pretreated with dimethoate for 28 days]
Suprun_2004_Bioelectrochemistry_63_281 Bi-enzyme sensor based on thick-film carbon electrode modified with electropolymerized tyramine
Szabo_2004_J.Nutr.Biochem_15_206 Large doses of zinc oxide increases the activity of hydrolases in rats
Tacke_2004_Scand.J.Gastroenterol_39_259 Analysis of factors contributing to higher erythropoietin levels in patients with chronic liver disease
Tai_2004_Curr.Opin.Lipidol_15_5 Genes, diet and serum lipid concentrations: lessons from ethnically diverse populations and their relevance to coronary heart disease in Asia
Takacs_2004_J.Mol.Evol_58_516 Cobra ( Naja spp. ) nicotinic acetylcholine receptor exhibits resistance to Erabu sea snake ( Laticauda semifasciata) short-chain alpha-neurotoxin
Takasaki_2004_Eur.J.Pharmacol_486_335 K579, a slow-binding inhibitor of dipeptidyl peptidase IV, is a long-acting hypoglycemic agent
Takino_2004_J.Agric.Food.Chem_52_727 Determination of carbamate pesticide residues in vegetables and fruits by liquid chromatography-atmospheric pressure photoionization-mass spectrometry and atmospheric pressure chemical ionization-mass spectrometry
Talmud_2004_Diabetes.Obes.Metab_6_1 Lipoprotein lipase gene variants and the effect of environmental factors on cardiovascular disease risk
Tan_2004_Am.J.Clin.Dermatol_5_79 Topical antibacterial treatments for acne vulgaris : comparative review and guide to selection
Tannock_2004_Front.Biosci_9_1728 Lipoprotein-matrix interactions in macrovascular disease in diabetes
Tarbah_2004_J.Anal.Toxicol_28_198 Acute poisoning with phosphamidon: determination of dimethyl phosphate (DMP) as a stable metabolite in a case of organophosphate insecticide intoxication
Tariot_2004_JAMA_291_317 Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: a randomized controlled trial
Tarui_2004_J.Agric.Food.Chem_52_538 Metabolism of diethofencarb (isopropyl 3,4-diethoxyphenylcarbamate) in rats: identification of metabolites in urine
Teaktong_2004_Neuropathol.Appl.Neurobiol_30_243 Selective changes in nicotinic acetylcholine receptor subtypes related to tobacco smoking: an immunohistochemical study
Teke_2004_J.Neurol.Neurosurg.Psychiatry_75_936 Organophosphate poisoning case with atypical clinical survey and magnetic resonance imaging findings
Tezuka_2004_Exp.Gerontol_39_91 Aging-related alterations in the contractile responses to acetylcholine, muscarinic cholinoceptors and cholinesterase activities in jejunum and colon of the male Fischer 344 rats
Tilly-Kiesi_2004_Metabolism_53_520 Lipoprotein metabolism in subjects with hepatic lipase deficiency
Tiwari_2004_Indian.J.Exp.Biol_42_413 Toxic and sub-lethal effects of oleandrin on biochemical parameters of fresh water air breathing murrel, Channa punctatus (Bloch.)
Tremolada_2004_Aquat.Toxicol_67_87 Quantitative inter-specific chemical activity relationships of pesticides in the aquatic environment
Trinidad_2004_J.Biol.Chem_279_31622 Neuregulin inhibits acetylcholine receptor aggregation in myotubes
Tsuge_2004_FEMS.Microbiol.Lett_231_77 An extra large insertion in the polyhydroxyalkanoate synthase from Delftia acidovorans DS-17: its deletion effects and relation to cellular proteolysis
Tsukada_2004_Synapse_52_1 Effects of acute acetylcholinesterase inhibition on the cerebral cholinergic neuronal system and cognitive function: Functional imaging of the conscious monkey brain using animal PET in combination with microdialysis
Tugal_2004_Int.J.Neuropsychopharmacol_7_117 A double-blind, placebo controlled, cross-over trial of adjunctive donepezil for cognitive impairment in schizophrenia
Tuovinen_2004_Toxicology_196_31 Organophosphate-induced convulsions and prevention of neuropathological damages
Turijski_2004_Methods.Find.Exp.Clin.Pharmacol_26_103 Influence of tacrine on dopamine-induced reactions of the gastric smooth muscle of rats
Tykva_2004_J.Chromatogr.A_1032_59 Radio-high-performance liquid chromatography for ecotoxicity assessment of insect growth regulators
Udaka_2004_Nihon.Ronen.Igakkai.Zasshi_41_1 [Pathophysiology and treatment of vascular dementia]
Uroz_2004_Synapse_51_173 Chemical anatomy of the human paraventricular thalamic nucleus
Valenti_2004_Cell.Mol.Life.Sci_61_945 Differential diurnal variations of anandamide and 2-arachidonoyl-glycerol levels in rat brain
van Beijsterveldt_2004_Arzneimittelforschung_54_85 Pharmacokinetics and tissue distribution of galantamine and galantamine-related radioactivity after single intravenous and oral administration in the rat
van der Schans_2004_Arch.Toxicol_78_508 Retrospective detection of exposure to nerve agents: analysis of phosphofluoridates originating from fluoride-induced reactivation of phosphylated BuChE
van Helden_2004_J.Appl.Toxicol_24_59 Low-level exposure of guinea pigs and marmosets to sarin vapour in air: lowest-observable-adverse-effect level (LOAEL) for miosis
Van Kampen_2004_Psychopharmacology.(Berl)_172_375 AR-R 17779 improves social recognition in rats by activation of nicotinic alpha7 receptors
Vargas_2004_Biotechnol.Lett_26_81 Lipase-producing microorganisms from a Kenyan alkaline soda lake
Venkatachalam_2004_Bioorg.Med.Chem_12_3371 Lipase-mediated stereoselective hydrolysis of stampidine and other phosphoramidate derivatives of stavudine
Verdier_2004_J.Pept.Sci_10_229 Amyloid beta-peptide interactions with neuronal and glial cell plasma membrane: binding sites and implications for Alzheimer's disease
Verges_2004_J.Biol.Chem_279_9030 Endocytosis of hepatic lipase and lipoprotein lipase into rat liver hepatocytes in vivo is mediated by the low density lipoprotein receptor-related protein
Vidair_2004_Toxicol.Appl.Pharmacol_196_287 Age dependence of organophosphate and carbamate neurotoxicity in the postnatal rat: extrapolation to the human
Vidinha_2004_Biotechnol.Bioeng_85_442 Effect of immobilization support, water activity, and enzyme ionization state on cutinase activity and enantioselectivity in organic media
Villeneuve_2004_Biotechnol.Lett_26_193 Toward the synthesis of pyroglutamate lauroyl ester: biocatalysis versus chemical catalysis
Voetsch_2004_Arch.Neurol_61_351 The combined effect of paraoxonase promoter and coding region polymorphisms on the risk of arterial ischemic stroke among young adults
Walkowiak_2004_J.Pediatr.Gastroenterol.Nutr_38_430 Serum lipase after secretin stimulation detects mild pancreatic involvement in cystic fibrosis
Walley_2004_CNS.Drugs_18_1 Neuropsychotherapeutics in the UK: what has been the impact of NICE on prescribing?
Wang_2004_Toxicol.Appl.Pharmacol_196_356 Resistance to organophosphorus agent toxicity in transgenic mice expressing the G117H mutant of human butyrylcholinesterase
Weber_2004_Chemosphere_55_157 Calculating pesticide sorption coefficients (Kd) using selected soil properties
Wei_2004_J.Ind.Microbiol.Biotechnol_31_133 Studies on a novel carbon source and cosolvent for lipase production by Candida rugosa
Weible_2004_Learn.Mem_11_108 Galantamine facilitates acquisition of hippocampus-dependent trace eyeblink conditioning in aged rabbits
Weik_2004_Biophys.J_86_3176 Temperature derivative fluorescence spectroscopy as a tool to study dynamical changes in protein crystals
Weiner_2004_Am.J.Pharmacogenomics_4_119 Functional screening of drug target genes: m1 muscarinic acetylcholine receptor phenotypes in degenerative dementias
Weinstock_2004_J.Neural.Transm.(Vienna)_111_347 Rat models of dementia based on reductions in regional glucose metabolism, cerebral blood flow and cytochrome oxidase activity
Wesley_2004_Int.J.Cancer_109_855 Role for dipeptidyl peptidase IV in tumor suppression of human non small cell lung carcinoma cells
Wignot_2004_Pharm.Res_21_420 In vitro studies of the effects of HAART drugs and excipients on activity of digestive enzymes
Wilson_2004_J.Comp.Neurol_474_13 Postnatal development of cholinergic synapses on mouse spinal motoneurons
Wimo_2004_Drugs.Aging_21_279 Cost effectiveness of cholinesterase inhibitors in the treatment of Alzheimer's disease: a review with methodological considerations
Wu_2004_Am.J.Physiol.Endocrinol.Metab_286_E711 Rapid downregulation of adipose tissue lipoprotein lipase activity on food deprivation: evidence that TNF-alpha is involved
Wyse_2004_Neurochem.Res_29_385 Arginine administration decreases cerebral cortex acetylcholinesterase and serum butyrylcholinesterase probably by oxidative stress induction
Xiong_2004_Zhongguo.Xiu.Fu.Chong.Jian.Wai.Ke.Za.Zhi_18_4 [Immunohistochemistry study of calcitonin gene-related peptide and substance P levels between end-to-end and end-to-side neurorrhaphy]
Yanai_2004_J.Pediatr.Surg_39_927 Acetylcholine-related bowel dysmotility in homozygous mutant NCX\/HOX11L.1-deficient (NCX-\/-) mice-evidence that acetylcholine is implicated in causing intestinal neuronal dysplasia
Yang_2004_Phytother.Res_18_160 Effect of Acanthopanax senticosus on lipoprotein lipase in 3T3-L1 adipocytes
Yasui-Furukori_2004_J.Clin.Pharmacol_44_538 The effects of Ginkgo biloba extracts on the pharmacokinetics and pharmacodynamics of donepezil
Ye_2004_J.Pharmacol.Exp.Ther_311_123 The modulating role of nuclear factor-kappaB in the action of alpha7-nicotinic acetylcholine receptor and cross-talk between 5-lipoxygenase and cyclooxygenase-2 in colon cancer growth induced by 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
Yen_2004_Shock_21_358 Depression of mitochondrial respiratory enzyme activity in rostral ventrolateral medulla during acute mevinphos intoxication in the rat
Yi_2004_Toxicol.Lett_147_109 Inhibitory effect of tellimagrandin I on chemically induced differentiation of human leukemia K562 cells
Yi_2004_Acta.Pharmacol.Sin_25_231 Effects of chebulinic acid on differentiation of human leukemia K562 cells
Yildiz_2004_Protein.J_23_143 Partial purification and characterization of soluble isoform of butyrylcholinesterase from rat intestine
Yu_2004_J.Lipid.Res_45_1614 Endothelial lipase is synthesized by hepatic and aorta endothelial cells and its expression is altered in apoE-deficient mice
Yu_2004_Am.J.Physiol.Renal.Physiol_286_F720 Vascular localization of soluble epoxide hydrolase in the human kidney
Zhang_2004_Environ.Toxicol_19_154 Detoxification of organophosphorus compounds by recombinant carboxylesterase from an insecticide-resistant mosquito and oxime-induced amplification of enzyme activity
Zhang_2004_Mutat.Res_558_63 Lack of increased genetic damage in 1,3-butadiene-exposed Chinese workers studied in relation to EPHX1 and GST genotypes
Zhang_2004_Mol.Pharmacol_66_538 Cholinergic drugs for Alzheimer's disease enhance in vitro dopamine release
Zhang_2004_Curr.Drug.Targets.CNS.Neurol.Disord_3_137 Cholinergic activity and amyloid precursor protein processing in aging and Alzheimer's disease
Zhang_2004_Acta.Pharmacol.Sin_25_431 Anti-epitope antibody, a novel site-directed antibody against human acetylcholinesterase
Zhao_2004_J.Am.Soc.Nephrol_15_1244 Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage
Zheng_2004_J.Nat.Prod_67_604 New biologically active triterpenoid saponins from Scabiosa tschiliensis
Zhu_2004_Biochim.Biophys.Acta_1676_251 Regulation of human microsomal epoxide hydrolase gene (EPHX1) expression by the transcription factor GATA-4
Zuo_2004_Alcohol.Clin.Exp.Res_28_688 Single-channel analyses of ethanol modulation of neuronal nicotinic acetylcholine receptors
He_2004_Pestic.Biochem.Physiol_78_103 Characterizations of general esterases in relation to malathion susceptibility in two field populations of the oriental migratory locust, Locusta migratoria manilensis (Meyen)
Zhou_2004_Pestic.Biochem.Physiol_78_114 Partial purification and characterization of a methyl-parathion resistance-associated general esterase in Diabrotica virgifera virgifera (Coleoptera: Chrysomelidae)
Sevgiler_2004_Pestic.Biochem.Physiol_78_1 Evaluation of etoxazole toxicity in the liver of Oreochromis niloticus
Russell_2004_Pestic.Biochem.Physiol_79_84 Two major classes of target site insensitivity mutations confer resistance to organophosphate and carbamate insecticides
Benini_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_1346 Purification, crystallization and preliminary X-ray analysis of an acetylxylan esterase from Bacillus pumilus. Erratum
Toivonen_2004_J.Soc.Gynecol.Investig_11_540 Low-activity haplotype of the microsomal epoxide hydrolase gene is protective against placental abruption
Tranah_2004_Carcinogenesis_25_1211 Epoxide hydrolase polymorphisms, cigarette smoking and risk of colorectal adenoma in the Nurses' Health Study and the Health Professionals Follow-up Study
Wilkening_2004_J.Biomol.Tech_15_107 Quantitative real-time polymerase chain reaction: methodical analysis and mathematical model
Xiao_2004_Chin.Med.J.(Engl)_117_661 Relationship between polymorphisms of genes encoding microsomal epoxide hydrolase and glutathione S-transferase P1 and chronic obstructive pulmonary disease
Xu_2004_Biotechnol.Lett_26_1217 Biocatalytic resolution of glycidyl aryl ethers by Trichosporon loubierii : cell\/substrate ratio influences the optical purity of (R) - epoxides
Yuasa_2004_Hum.Biol_76_479 Molecular basis of ESD*5 and ESD*7 and haplotype analysis with new polymorphisms in introns
Zaitsu_2004_Respir.Med_98_235 Disodium cromoglycate suppresses the induction of cysteinyl leukotriene synthesis during granulocytic differentiation in HL-60 cells
Zhang_2004_Zhonghua.Lao.Dong.Wei.Sheng.Zhi.Ye.Bing.Za.Zhi_22_176 [Relationship of genetic polymorphism of microsomal epoxide hydrolase with susceptibility of chronic benzene poisoning]
Zhang_2004_Biotechnol.Prog_20_1567 Bioremediation of organophosphorus pesticides by surface-expressed carboxylesterase from mosquito on Escherichia coli
Zhao_2004_J.Am.Chem.Soc_126_11156 Epoxide hydrolase-catalyzed enantioselective synthesis of chiral 1,2-diols via desymmetrization of meso-epoxides. lzhao@diversa.com
Zhou_2004_Life.Sci_74_935 Herbal bioactivation: the good, the bad and the ugly
Zhu_2004_J.Biol.Chem_279_29902 CCAAT\/enhancer-binding protein alpha (C\/EBPalpha) activates transcription of the human microsomal epoxide hydrolase gene (EPHX1) through the interaction with DNA-bound NF-Y
Zou_2004_Planta.Med_70_289 Kava does not display metabolic toxicity in a homogeneous cellular assay
Berthier_2004_Neurologia_19 Suppl 2_64 [Advances in the therapy of dementia.]
Warner_2004_Clin.Evid__1361 Dementia
Wan_2004_Proc.Natl.Acad.Sci.U.S.A_101_15724 Large-scale cDNA transfection screening for genes related to cancer development and progression
Levavi-Sivan_2004_Aquaculture_229_419 Spawning induction and hormonal levels during final oocyte maturation in the silver perch (Bidyanus bidyanus)
Peres_2004_Aquaculture_235_423 Growth, chemical composition and resistance to Streptococcus iniae challenge of juvenile Nile tilapia (Oreochromis niloticus) fed graded levels of dietary inositol
Minh_2004_Aquaculture_234_601 Growth, survival, haemolymph osmolality and organosomatic indices of the western king prawn (Penaeus latisulcatus Kishinouye, 1896) reared at different salinities
Darbro_2004_Pest.Manag.Sci_60_901 Assessing insecticide resistance and aversion to methomyl-treated toxic baits in Musca domestica L (Diptera: Muscidae) populations in southern California
Hamilton_2004_Pest.Manag.Sci_60_311 Pesticide residues in food acute dietary exposure
Kristensen_2004_Pest.Manag.Sci_60_894 Cross-resistance potential of fipronil in Musca domestica
Quero_2004_Pest.Manag.Sci_60_719 Responses of the olfactory receptor neurons of the corn stalk borer Sesamia nonagrioides to components of the pheromone blend and their inhibition by a trifluoromethyl ketone analogue of the main component
Kim_2004_J.Asia.Pac.Entomol_7_187 Insecticide Sensitivity of Acetylcholinesterase from a Korean Housefly (Musca domestica) Strain to Organophosphates
Im_2004_J.Asia.Pac.Entomol_7_81 Purification and Partial cDNA Sequence of Acetylcholinesterase from a Korean Strain of the Housefly, Musca domestica
Frasca_2004_Nephrol.Dial.Transplant_19_1622 A 33-year-old man with nephrotic syndrome and lecithin-cholesterol acyltransferase (LCAT) deficiency. Description of two new mutations in the LCAT gene
Cohen_2004_Science_305_869 Multiple rare alleles contribute to low plasma levels of HDL cholesterol
Maruyama_2004_J.Atheroscler.Thromb_11_131 Mutations in Japanese subjects with primary hyperlipidemia--results from the Research Committee of the Ministry of Health and Welfare of Japan since 1996
Parman_2004_Brain_127_2540 Clinicopathological and genetic study of early-onset demyelinating neuropathy
Canaan_2004_J.Biol.Chem_279_14502 Interfacial enzymology of parvovirus phospholipases A2
Nielsen_2004_J.Magn.Reson_169_129 Comparing continuous wave progressive saturation EPR and time domain saturation recovery EPR over the entire motional range of nitroxide spin labels
Vincentelli_2004_Protein.Sci_13_2782 High-throughput automated refolding screening of inclusion bodies
Adams_2004_J.Neurosci_24_10302 Structural abnormalities at neuromuscular synapses lacking multiple syntrophin isoforms
Angelini_2004_Eur.J.Histochem_48_235 Acetylcholine synthesis and possible functions during sea urchin development
Baker_2004_Mol.Pharmacol_65_453 Pharmacological properties of alpha 9 alpha 10 nicotinic acetylcholine receptors revealed by heterologous expression of subunit chimeras
Bouzat_2004_Nature_430_896 Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel
Craig_2004_Eur.J.Pharmacol_502_31 Stable expression and characterisation of a human alpha 7 nicotinic subunit chimera: a tool for functional high-throughput screening
Ellison_2004_Biochemistry_43_16019 Alpha-conotoxins ImI and ImII target distinct regions of the human alpha7 nicotinic acetylcholine receptor and distinguish human nicotinic receptor subtypes
Lansdell_2004_J.Neurochem_90_479 Molecular characterization of Dalpha6 and Dalpha7 nicotinic acetylcholine receptor subunits from Drosophila: formation of a high-affinity alpha-bungarotoxin binding site revealed by expression of subunit chimeras
Lee_2004_J.Gen.Physiol_124_555 Invariant aspartic Acid in muscle nicotinic receptor contributes selectively to the kinetics of agonist binding
Luvisetto_2004_Behav.Pharmacol_15_233 Central injection of botulinum neurotoxins: behavioural effects in mice
Pons_2004_Eur.J.Neurosci_20_2022 Critical role of the C-terminal segment in the maturation and export to the cell surface of the homopentameric alpha 7-5HT3A receptor
Rigoni_2004_J.Cell.Sci_117_3561 Snake presynaptic neurotoxins with phospholipase A2 activity induce punctate swellings of neurites and exocytosis of synaptic vesicles
Rossetto_2004_Toxicol.Lett_149_91 Different mechanism of blockade of neuroexocytosis by presynaptic neurotoxins
Shiao_2004_Hum.Mol.Genet_13_1873 Defects in neuromuscular junction structure in dystrophic muscle are corrected by expression of a NOS transgene in dystrophin-deficient muscles, but not in muscles lacking alpha- and beta1-syntrophins
Sine_2004_Curr.Med.Chem_11_559 Toward atomic-scale understanding of ligand recognition in the muscle nicotinic receptor
Trombino_2004_Curr.Med.Chem.Anticancer.Agents_4_535 Role of the non-neuronal human cholinergic system in lung cancer and mesothelioma: possibility of new therapeutic strategies
Trombino_2004_Cancer.Res_64_135 Alpha7-nicotinic acetylcholine receptors affect growth regulation of human mesothelioma cells: role of mitogen-activated protein kinase pathway
Domino_2004_Prog.Neuropsychopharmacol.Biol.Psychiatry_28_801 N-methyl-D-aspartate antagonists as drug models of schizophrenia: a surprising link to tobacco smoking
Flora_2004_Toxicology_195_127 Therapeutic potential of monoisoamyl and monomethyl esters of meso 2,3-dimercaptosuccinic acid in gallium arsenide intoxicated rats
Gemignani_2004_Arch.Ital.Biol_142_1 Influence of mental motor imagery on the execution of a finger-to-thumb opposition task
Jiang_2004_J.Neurophysiol_91_248 Taurine activates strychnine-sensitive glycine receptors in neurons freshly isolated from nucleus accumbens of young rats
Krnjevic_2004_Biochem.Pharmacol_68_1549 How does a little acronym become a big transmitter?
Krnjevic_2004_Prog.Brain.Res_145_81 Synaptic mechanisms modulated by acetylcholine in cerebral cortex
Minniti_2004_J.Cell.Sci_117_5179 Caenorhabditis elegans syndecan (SDN-1) is required for normal egg laying and associates with the nervous system and the vulva
Morgan_2004_Prog.Neurobiol_74_323 Structure and function of amyloid in Alzheimer's disease
Petrikovics_2004_Toxicol.Sci_77_258 Comparing therapeutic and prophylactic protection against the lethal effect of paraoxon
Rose_2004_Brain.Res_1015_96 Glycosaminoglycan C3 protects against AF64A-induced cholinotoxicity in a dose-dependent and time-dependent manner
Ye_2004_J.Neurosci_24_8961 Presynaptic glycine receptors on GABAergic terminals facilitate discharge of dopaminergic neurons in ventral tegmental area
Bhattacharya_2004_J.Neurosci_24_5537 Uropathic observations in mice expressing a constitutively active point mutation in the 5-HT3A receptor subunit
Dahan_2004_Proc.Natl.Acad.Sci.U.S.A_101_10195 A fluorophore attached to nicotinic acetylcholine receptor beta M2 detects productive binding of agonist to the alpha delta site
Orb_2004_Physiol.Genomics_18_299 Knockin mice with Leu9'Ser alpha4-nicotinic receptors: substantia nigra dopaminergic neurons are hypersensitive to agonist and lost postnatally
Pittock_2004_Ann.Neurol_56_715 Paraneoplastic antibodies coexist and predict cancer, not neurological syndrome
Sandroni_2004_Arch.Neurol_61_44 Idiopathic autonomic neuropathy: comparison of cases seropositive and seronegative for ganglionic acetylcholine receptor antibody
Tapper_2004_Science_306_1029 Nicotine activation of alpha4* receptors: sufficient for reward, tolerance, and sensitization
Thieben_2004_Neurology_62_1177 Potentially reversible autoimmune limbic encephalitis with neuronal potassium channel antibody
Vernino_2004_J.Neurosci_24_7037 Passive transfer of autoimmune autonomic neuropathy to mice
Vernino_2004_Clin.Cancer.Res_10_7270 Autoantibody profiles and neurological correlations of thymoma
Pepeu_2004_Learn.Mem_11_21 Changes in acetylcholine extracellular levels during cognitive processes
Rosi_2004_Neurosci.Lett_361_120 S 18986, a positive modulator of AMPA receptors with cognition-enhancing properties, increases ACh release in the hippocampus of young and aged rat
Greenfield_2004_J.Neurochem_90_325 A novel peptide modulates alpha7 nicotinic receptor responses: implications for a possible trophic-toxic mechanism within the brain
Hogg_2004_Science_306_983 Neuroscience. What genes tell us about nicotine addiction
Hogg_2004_Curr.Drug.Targets.CNS.Neurol.Disord_3_123 Nicotinic acetylcholine receptors as drug targets
Hogg_2004_Eur.J.Neurosci_19_2410 Functional maturation of isolated neural progenitor cells from the adult rat hippocampus
Mogg_2004_Neuropharmacol_47_848 Functional responses and subunit composition of presynaptic nicotinic receptor subtypes explored using the novel agonist 5-iodo-A-85380
Oliveira_2004_J.Physiol_560_157 Tetanic depression is overcome by tonic adenosine A(2A) receptor facilitation of L-type Ca(2+) influx into rat motor nerve terminals
Watson_2004_Neurology_63_43 Absence of antibodies to glutamate receptor type 3 (GluR3) in Rasmussen encephalitis
Young_2004_Neuropsychopharmacology_29_891 Nicotine improves sustained attention in mice: evidence for involvement of the alpha7 nicotinic acetylcholine receptor
Avraham_2004_Pharmacol.Biochem.Behav_77_675 Very low doses of delta 8-THC increase food consumption and alter neurotransmitter levels following weight loss
Ogier_2004_Eur.J.Neurosci_20_2591 Identified spinal motoneurons of young rats possess nicotinic acetylcholine receptors of the heteromeric family
Tribollet_2004_Neurosci_124_405 Comparative distribution of nicotinic receptor subtypes during development, adulthood and aging: an autoradiographic study in the rat brain
Wang_2004_J.Neurol.Sci_222_87 Nicotinic acetylcholine receptor alpha5 subunits modulate oxotremorine-induced salivation and tremor
Celie_2004_Neuron_41_907 Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures
Eiden_2004_Pflugers.Arch_447_636 The vesicular amine transporter family (SLC18): amine\/proton antiporters required for vesicular accumulation and regulated exocytotic secretion of monoamines and acetylcholine
Karlin_2004_Neuron_41_841 A touching picture of nicotinic binding
Karlin_2004_Biotechniques_36_1010 Transfer in SDS of biotinylated proteins from acrylamide gels to an avidin-coated membrane filter
Kedmi_2004_Physiol.Genomics_17_221 Mice lacking neuronal nicotinic acetylcholine receptor beta4-subunit and mice lacking both alpha5- and beta4-subunits are highly resistant to nicotine-induced seizures
Maiti_2004_J.Neuroimmunol_152_112 Immunosuppression of rat myasthenia gravis by oral administration of a syngeneic acetylcholine receptor fragment
Caner_2004_Drug.Discov.Today_9_105 Trends in the development of chiral drugs
Lowe_2004_Biochim.Biophys.Acta_1661_40 Polarized distribution of Na+, K(+)-ATPase alpha-subunit isoforms in electrocyte membranes
Bidoia_2004_Science_303_1977\; author reply 1977 Comment on Reelin promotes peripheral synapse elimination and maturation
Buffelli_2004_News.Physiol.Sci_19_85 Activity-dependent synaptic competition at mammalian neuromuscular junctions
Zuo_2004_J.Neurosci_24_10999 Fluorescent proteins expressed in mouse transgenic lines mark subsets of glia, neurons, macrophages, and dendritic cells for vital examination
Diaz-Hernandez_2004_J.Pharmacol.Exp.Ther_311_954 Interaction between dinucleotide and nicotinic receptors in individual cholinergic terminals
Gahring_2004_J.Comp.Neurol_468_334 Mouse strain-specific nicotinic acetylcholine receptor expression by inhibitory interneurons and astrocytes in the dorsal hippocampus
Gahring_2004_J.Comp.Neurol_468_322 Neuronal and astrocyte expression of nicotinic receptor subunit beta4 in the adult mouse brain
Gotti_2004_Prog.Neurobiol_74_363 Neuronal nicotinic receptors: from structure to pathology
Hibbs_2004_J.Biol.Chem_279_28483 Acrylodan-conjugated cysteine side chains reveal conformational state and ligand site locations of the acetylcholine-binding protein
Ibanez_2004_FEBS.Lett_578_121 Modulation of botulinum neurotoxin A catalytic domain stability by tyrosine phosphorylation
Krejci_2004_Physiol.Res_53 Suppl 1_S131 Regulation of signal transduction at M2 muscarinic receptor
Taylor_2004_Bioorg.Med.Chem.Lett_14_1875 Contemporary paradigms for cholinergic ligand design guided by biological structure
Severance_2004_Mol.Pharmacol_66_420 The alpha7 nicotinic acetylcholine receptor subunit exists in two isoforms that contribute to functional ligand-gated ion channels
Suszkiw_2004_Neurotoxicol_25_599 Presynaptic disruption of transmitter release by lead
Torrella_2004_Ann.N.Y.Acad.Sci_1021_399 Developmental differences in nicotine place conditioning
Zhou_2004_Brain.Res_999_142 Nicotine attenuates spatial learning deficits induced in the rat by perinatal lead exposure
Del Signore_2004_J.Neuropathol.Exp.Neurol_63_138 Nicotinic acetylcholine receptor subtypes in the rat sympathetic ganglion: pharmacological characterization, subcellular distribution and effect of pre- and postganglionic nerve crush
Abdalla_2004_Mol.Cell.Endocrinol_213_139 Effect of estrogen on muscarinic acetylcholine receptor expression in rat myometrium
Alkondon_2004_J.Neurosci_24_4635 Targeted deletion of the kynurenine aminotransferase ii gene reveals a critical role of endogenous kynurenic acid in the regulation of synaptic transmission via alpha7 nicotinic receptors in the hippocampus
Bruno_2004_J.Neurosci_24_8009 Long-lasting rescue of age-associated deficits in cognition and the CNS cholinergic phenotype by a partial agonist peptidomimetic ligand of TrkA
Cardoso_2004_Neuroendocrinology_80_379 Effects of estrogen on muscarinic acetylcholine receptors in the rat hippocampus
Hernandez_2004_Mol.Pharmacol_66_978 The nicotinic receptor in the rat pineal gland is an alpha3beta4 subtype
Khiroug_2004_Neurosci_124_817 Rat nicotinic acetylcholine receptor alpha2beta2 channels: comparison of functional properties with alpha4beta2 channels in Xenopus oocytes
Klein_2004_Neurosci_127_563 Inhibition of nicotinic acetylcholine receptors by apolipoprotein E-derived peptides in rat hippocampal slices
Lai_2004_Neurosci_127_399 Selective recovery of striatal 125I-alpha-conotoxinmii nicotinic receptors after nigrostriatal damage in monkeys
Lucas_2004_Life.Sci_75_1761 Effects of carbachol on rat Sertoli cell proliferation and muscarinic acetylcholine receptors regulation: an in vitro study
Michailov_2004_Science_304_700 Axonal neuregulin-1 regulates myelin sheath thickness
Placzek_2004_Mol.Pharmacol_66_169 A single point mutation confers properties of the muscle-type nicotinic acetylcholine receptor to homomeric alpha7 receptors
Ramien_2004_J.Comp.Neurol_469_83 Parasympathetic nerve fibers invade the upper dermis following sensory denervation of the rat lower lip skin
Stokes_2004_Mol.Pharmacol_66_14 The structural basis for GTS-21 selectivity between human and rat nicotinic alpha7 receptors
Wei_2004_Bioorg.Med.Chem.Lett_14_1855 Synthesis and pharmacological characterization of bivalent ligands of epibatidine at neuronal nicotinic acetylcholine receptors
Xiao_2004_Bioorg.Med.Chem.Lett_14_1845 Pharmacology of the agonist binding sites of rat neuronal nicotinic receptor subtypes expressed in HEK 293 cells
Xiao_2004_J.Pharmacol.Exp.Ther_310_98 The comparative pharmacology and up-regulation of rat neuronal nicotinic receptor subtype binding sites stably expressed in transfected mammalian cells
Yakel_2004_Prog.Brain.Res_145_95 Functional and molecular characterization of neuronal nicotinic ACh receptors in rat hippocampal interneurons
Sankaranarayanan_2004_J.Biol.Chem_279_50810 Nrf3 negatively regulates antioxidant-response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene
Herzog_2004_Eur.J.Neurosci_20_1752 Expression of vesicular glutamate transporters, VGLUT1 and VGLUT2, in cholinergic spinal motoneurons
Kim_2004_J.Biol.Chem_279_12580 The vesicular acetylcholine transporter interacts with clathrin-associated adaptor complexes AP-1 and AP-2
Vougier_2004_J.Biol.Chem_279_30210 Essential role of methionine residues in calmodulin binding to Bordetella pertussis adenylate cyclase, as probed by selective oxidation and repair by the peptide methionine sulfoxide reductases
Becher_2004_Biochem.Biophys.Res.Commun_321_981 Ectopically expressed gamma-aminobutyric acid receptor B is functionally down-regulated in isolated lipid raft-enriched membranes
Blein_2004_J.Biol.Chem_279_48292 Structural analysis of the complement control protein (CCP) modules of GABA(B) receptor 1a: only one of the two CCP modules is compactly folded
McIlhinney_2004_Methods.Mol.Biol_259_81 Generation and use of epitope-tagged receptors
Mundell_2004_Biochemistry_43_7541 Desensitization and internalization of metabotropic glutamate receptor 1a following activation of heterologous Gq\/11-coupled receptors
Aharoni_2004_Discov.Med_4_120 Directed evolution of recombinant serum paraoxonase (PON) variants
Aviram_2004_Free.Radic.Biol.Med_37_1301 Introduction to the serial review on paraoxonases, oxidative stress, and cardiovascular diseases
Aviram_2004_Free.Radic.Biol.Med_37_1304 Paraoxonases 1, 2, and 3, oxidative stress, and macrophage foam cell formation during atherosclerosis development
Aviram_2004_Clin.Nutr_23_423 Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation
Berkowitz_2004_Environ.Health.Perspect_112_388 In utero pesticide exposure, maternal paraoxonase activity, and head circumference
Boemi_2004_Diabet.Med_21_423 Smoking is associated with reduced serum levels of the antioxidant enzyme, paraoxonase, in Type 2 diabetic patients
Bruhl_2004_Life.Sci_75_1609 Release of choline in the isolated heart, an indicator of ischemic phospholipid degradation and its protection by ischemic preconditioning: no evidence for a role of phospholipase D
Calabresi_2004_Metabolism_53_153 An omega-3 polyunsaturated fatty acid concentrate increases plasma high-density lipoprotein 2 cholesterol and paraoxonase levels in patients with familial combined hyperlipidemia
Deakin_2004_Clin.Sci.(Lond)_107_435 Genetic and environmental factors modulating serum concentrations and activities of the antioxidant enzyme paraoxonase-1
Fortunato_2004_Clin.Chem_50_2012 Paraoxonase and superoxide dismutase gene polymorphisms and noise-induced hearing loss
Fuhrman_2004_Biochem.Biophys.Res.Commun_322_974 Acetylcholine esterase protects LDL against oxidation
Gosens_2004_Eur.J.Pharmacol_500_193 Acetylcholine: a novel regulator of airway smooth muscle remodelling?
Harangi_2004_Eur.J.Clin.Pharmacol_60_685 Atorvastatin effect on high-density lipoprotein-associated paraoxonase activity and oxidative DNA damage
Harel_2004_Nat.Struct.Mol.Biol_11_412 Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes
Hayek_2004_J.Cardiovasc.Pharmacol_43_140 Omapatrilat decreased macrophage oxidative status and atherosclerosis progression in atherosclerotic apolipoprotein E-deficient mice
James_2004_Free.Radic.Biol.Med_37_1986 The importance of high-density lipoproteins for paraoxonase-1 secretion, stability, and activity
Liu_2004_Nutr.Metab.Cardiovasc.Dis_14_81 Associations between HDL oxidation and paraoxonase-1 and paraoxonase-1 gene polymorphisms in families affected by familial combined hyperlipidemia
Mackness_2004_Curr.Opin.Lipidol_15_399 Paraoxonase 1 activity, concentration and genotype in cardiovascular disease
Mackness_2004_Free.Radic.Biol.Med_37_1317 Paraoxonase 1 and atherosclerosis: is the gene or the protein more important?
Navab_2004_Circulation_109_3215 Oral D-4F causes formation of pre-beta high-density lipoprotein and improves high-density lipoprotein-mediated cholesterol efflux and reverse cholesterol transport from macrophages in apolipoprotein E-null mice
Navab_2004_Curr.Opin.Lipidol_15_645 Human apolipoprotein A-I and A-I mimetic peptides: potential for atherosclerosis reversal
Navab_2004_Arterioscler.Thromb.Vasc.Biol_24_392 Apparent paradox of low-fat healthy diets increasing plasma levels of oxidized low-density lipoprotein and lipoprotein(a)
Paragh_2004_Curr.Med.Res.Opin_20_1321 Effect of short term treatment with simvastatin and atorvastatin on lipids and paraoxonase activity in patients with hyperlipoproteinaemia
Rosenblat_2004_Arterioscler.Thromb.Vasc.Biol_24_175 Decreased macrophage paraoxonase 2 expression in patients with hypercholesterolemia is the result of their increased cellular cholesterol content: effect of atorvastatin therapy
Seres_2004_Exp.Gerontol_39_59 Study of factors influencing the decreased HDL associated PON1 activity with aging
Shiner_2004_Free.Radic.Biol.Med_37_2052 Paraoxonase 2 (PON2) expression is upregulated via a reduced-nicotinamide-adenine-dinucleotide-phosphate (NADPH)-oxidase-dependent mechanism during monocytes differentiation into macrophages
Teiber_2004_J.Lipid.Res_45_2260 Purified human serum PON1 does not protect LDL against oxidation in the in vitro assays initiated with copper or AAPH
Beltowski_2004_J.Cardiovasc.Pharmacol_43_121 Effect of 3-hydroxy-3-methylglutarylcoenzyme A reductase inhibitors (statins) on tissue paraoxonase 1 and plasma platelet activating factor acetylhydrolase activities
Ferretti_2004_J.Clin.Endocrinol.Metab_89_2957 Protective effect of paraoxonase activity in high-density lipoproteins against erythrocyte membranes peroxidation: a comparison between healthy subjects and type 1 diabetic patients
Martinelli_2004_Eur.J.Clin.Invest_34_14 Interaction between smoking and PON2 Ser311Cys polymorphism as a determinant of the risk of myocardial infarction
Szymczyk_2004_Ginekol.Pol_75_528 [Decrease of paraoxonase activity in the first day after abdominal operations in women]
Barbieri_2004_Exp.Gerontol_39_1095 Gender specific association of genetic variation in peroxisome proliferator-activated receptor (PPAR)gamma-2 with longevity
Rea_2004_Exp.Gerontol_39_629 Paraoxonase polymorphisms PON1 192 and 55 and longevity in Italian centenarians and Irish nonagenarians. A pooled analysis
Liberopoulos_2004_Perit.Dial.Int_24_580 Alterations of paraoxonase and platelet-activating factor acetylhydrolase activities in patients on peritoneal dialysis
Bravo_2004_J.Forensic.Sci_49_379 Reliable, sensitive, rapid and quantitative enzyme-based assay for gamma-hydroxybutyric acid (GHB)
Bravo_2004_J.Neurochem_91_766 Choline is transported by vesicular acetylcholine transporter
Bravo_2004_Biochemistry_43_8787 Transmembrane reorientation of the substrate-binding site in vesicular acetylcholine transporter
Nash_2004_J.Biol.Chem_279_49036 Synaptic activity augments muscarinic acetylcholine receptor-stimulated inositol 1,4,5-trisphosphate production to facilitate Ca2+ release in hippocampal neurons
Nelson_2004_J.Pharmacol.Exp.Ther_310_1255 Functional selectivity of muscarinic receptor antagonists for inhibition of M3-mediated phosphoinositide responses in guinea pig urinary bladder and submandibular salivary gland
Ojeda_2004_Biochemistry_43_11163 Acetylcholine binding site in the vesicular acetylcholine transporter
Willets_2004_J.Neurosci_24_4157 Imaging of muscarinic acetylcholine receptor signaling in hippocampal neurons: evidence for phosphorylation-dependent and -independent regulation by G-protein-coupled receptor kinases
Young_2004_J.Neurochem_89_1537 NMDA-receptor regulation of muscarinic-receptor stimulated inositol 1,4,5-trisphosphate production and protein kinase C activation in single cerebellar granule neurons
Esteban_2004_Toxicol.Lett_151_243 Detection of clinical interactions between methadone and anti-retroviral compounds using an enantioselective capillary electrophoresis for methadone analysis
Quesada_2004_Toxicol.Lett_151_163 Bovine chromaffin cell cultures as model to study organophosporus neurotoxicity
Sogorb_2004_Toxicol.Lett_151_219 Future applications of phosphotriesterases in the prophylaxis and treatment of organophosporus insecticide and nerve agent poisonings
Dubois-Dauphin_2004_J.Comp.Neurol_474_108 Induction of enhanced green fluorescent protein expression in response to lesions in the nervous system
Hoyte_2004_Am.J.Pathol_164_711 Transgenic overexpression of dystroglycan does not inhibit muscular dystrophy in mdx mice
Hribar_2004_Eur.J.Neurosci_20_635 Voltage-gated K+ current: a marker for apoptosis in differentiating neuronal progenitor cells?
Jones_2004_J.Neurol.Sci_217_143 Muscular dystrophy with truncated dystrophin in a family of Japanese Spitz dogs
Nathan_2004_Endocrinology_145_3065 Estrogen facilitates neurite extension via apolipoprotein E in cultured adult mouse cortical neurons
Nathan_2004_Behav.Brain.Res_150_1 Olfactory function in apoE knockout mice
Roe_2004_Brain.Res.Mol.Brain.Res_120_91 Nicotinic stimulation modulates tyrosine hydroxylase mRNA half-life and protein binding to the 3'UTR in a manner that requires transcription
Anglister_2004_Cholinergic.Mechanisms.CRC.Press__145 Miriam M Salpeter (Mika) - bibliographical notes
Whittaker_2004_Cholinergic.Mechanisms.CRC.Press__1 In memoriam Edith Heilbronn
Samson_2004_Cholinergic.Mechanisms.CRC.Press__45 The mechanism for acetylcholine receptor inhibition by alpha-neurotoxins and species-specific resistance to alpha-bungarotoxin revea.
Albuquerque_2004_Cholinergic.Mechanisms.CRC.Press__297 Nicotinic receptor modulation.
Duttaroy_2004_Cholinergic.Mechanisms.CRC.Press__63 Generation and analysis of muscarinic acetylcholine receptor knockout mice.
Amitai_2004_Cholinergic.Mechanisms.CRC.Press__277 Bifunctional compounds eliciting both anti-inflammatory and cholinergic activity as potential drugs for CNS disorders.
Engel_2004_Cholinergic.Mechanisms.CRC.Press__213 Congenital myasthenic syndromes.
Andrews_2004_Cholinergic.Mechanisms.CRC.Press__453 A single amino acid substitution found in pirimicarb-insensitive acetylcholinesterase of the peach-potato aphid, Myzus persicae (Sulz.
Vincent_2004_Cholinergic.Mechanisms.CRC.Press__227 Antibodies to acetylcholine receptors and MuSK in myasthenia gravis and related disorders.
Fendyur_2004_Cholinergic.Mechanisms.CRC.Press__87 Neuronal calcium dynamics.
Antollini_2004_Cholinergic.Mechanisms.CRC.Press__33 Structure and dynamics of acetylcholine receptor and its lipid microenvironment.
Ordentlich_2004_Cholinergic.Mechanisms.CRC.Press__177 Surprising findings from the functional analysis of human acetylcholinesterase adducts of Alzheimer?s disease drugs.
Karlin_2004_Cholinergic.Mechanisms.CRC.Press__7 Nicotinic acetylcholine receptors.
Avraham_2004_Cholinergic.Mechanisms.CRC.Press__455 The effect of diet restriction, separation stress, activity wheel and tyrosine administration on cognitive function and the cholinergic system in mice.
Bancila_2004_Cholinergic.Mechanisms.CRC.Press__459 Nicotine induces glutamate release from hippocampal mossy fiber synaptosomes.
Blum_2004_Cholinergic.Mechanisms.CRC.Press__489 Superior cervical ganglia of the cat.
Bertrand_2004_Cholinergic.Mechanisms.CRC.Press__481 Role of spontaneous mutations of neuronal nicotinic acetylcholine receptors in ADNFLE.
Bloc_2004_Cholinergic.Mechanisms.CRC.Press__485 Quantal acetylcholine release through mediatophore proteolipid.
Boss_2004_Cholinergic.Mechanisms.CRC.Press__493 Cholinergic modulation of chemotaxis in human melanoma cells.
Brovtsyna_2004_Cholinergic.Mechanisms.CRC.Press__497 Some considerations concerning the molecular mechanism of cholinesterase catalysis.
Browne_2004_Cholinergic.Mechanisms.CRC.Press__499 Muscarinic neuromodulation in the hippocampus and parahippocampal region.
Bueters_2004_Cholinergic.Mechanisms.CRC.Press__255 Therapeutic efficacy in organophosphate poisoning by inhibiting central release of acetylcholine.
Shutz_2004_Cholinergic.Mechanisms.CRC.Press__691 Targeting of the vesicular acetylcholine transporter to cholinergic subdivisions in transgenic mice.
Shutz_2004_Cholinergic.Mechanisms.CRC.Press__125 Transcriptional control of the cholinergic gene locus.
Kronman_2004_Cholinergic.Mechanisms.CRC.Press__613 Some basic rules governing oligosaccharide-dependent circulatory residence of glycoproteins are revealed by MALDI-TOF mapping of the multiple N-glycans associated with recombinant bovine acetylcholinesterase.
Charpantier_2004_Cholinergic.Mechanisms.CRC.Press__509 Candoxin.
Chitlaru_2004_Cholinergic.Mechanisms.CRC.Press__511 Effect of post-translation modifications of human acetylcholinesterase on its circulatory residence.
Che_2004_Cholinergic.Mechanisms.CRC.Press__39 Site-directed reactive probes for structural and functional investigation of cholinergic proteins.
Luo_2004_Cholinergic.Mechanisms.CRC.Press__627 Two possible orientations of the HI-6 molecule in the reactivation of organophosphate-inhibited acetylcholinesterase.
Cohen_2004_Cholinergic.Mechanisms.CRC.Press__519 Generation of pharmacokinetically improved recombinant human acetylcholinesterase by polyethylene glycol modification.
Cordeiro_2004_Cholinergic.Mechanisms.CRC.Press__527 A calcium-proton antiport in presynaptic nerve terminals.
Cottage_2004_Cholinergic.Mechanisms.CRC.Press__531 Buprofezin and novaluron inhibit acetylcholinesterase activity in B-biotype Bemisia tabaci.
Cuello_2004_Cholinergic.Mechanisms.CRC.Press__375 Cholinergic cortical terminations establish classical synapses and undergo age-related atrophy.
Kaplan_2004_Cholinergic.Mechanisms.CRC.Press__601 Attempts to engineer an enzyme mimic of butyrylcholinesterase by substitution of the six divergent aromatic amino acids in the active center of acetylcholinesterase.
Rochu_2004_Cholinergic.Mechanisms.CRC.Press__675 Capillary zone electrophoresis detects unwanted cholinesterase-bound hidden ligands that alter enzyme conformational stability.
Sattelle_2004_Cholinergic.Mechanisms.CRC.Press__199 Molecular and functional diversity in the nicotinic acetylcholine receptor gene families of Caenorhabditis elegans and Drosophila melanogaster.
Comoletti_2004_Cholinergic.Mechanisms.CRC.Press__523 Interaction of recombinant soluble neuroligin-1 with neurexin-1-_.
Dergousova_2004_Cholinergic.Mechanisms.CRC.Press__547 E. coli-expressed extracellular domain of rat 7 nicotinic acetylcholine receptor.
Woodruff-Pak_2004_Cholinergic.Mechanisms.CRC.Press__323 Preclinical studies of galantamine using a form of associative learning severely impaired Alzheimer?s disease.
Combes_2004_Cholinergic.Mechanisms.CRC.Press__187 Structure and expression of the four acetylcholinesterase genes in the nematode Caenorhabditis elegans.
Gur_2004_Cholinergic.Mechanisms.CRC.Press__585 The interaction of 2-aminoperimidine with cholinesterases.
Drews_2004_Cholinergic.Mechanisms.CRC.Press__555 Calcium mobilization and cellular contraction of embryonic lens vesicle and neural tube on muscarinic cholinergic stimulation.
Salpeter_2004_Cholinergic.Mechanisms.CRC.Press__147 Chemical kinetics parameters and receptor degradation rates at the neuromuscular junction.
Sklan_2004_Cholinergic.Mechanisms.CRC.Press__707 Two-hybrid approach to the intracellular function(s) of readthrough acetylcholinesterase.
Duysen_2004_Cholinergic.Mechanisms.CRC.Press__559 Phenotype of the adult acetylcholinesterase-deficient mouse.
Reiner_2004_Cholinergic.Mechanisms.CRC.Press__289 In memoriam: Miroslav Brzin (13 April 1923- 8 August 1999)
Reiner_2004_Cholinergic.Mechanisms.CRC.Press__673 Peripheral binding of ethopropazine to horse serum butyrylcholinesterase.
Reiner_2004_Cholinergic.Mechanisms.CRC.Press__705 Kinetics of interaction of ethopropazine enantiomers with butyrylcholinesterase and acetylcholinesterase.
Avivi_2004_Cholinergic.Mechanisms.CRC.Press__423 Persistent blood-brain barrier disruption in humans.
Meshorer_2004_Cholinergic.Mechanisms.CRC.Press__119 The molecular neurobiology of acetylcholinesterase variants.
Elhanany_2004_Cholinergic.Mechanisms.CRC.Press__563 MALDI-TOF\/MS analysis of tabun-acetylcholinesterase conjugate.
Giacobini_2004_Cholinergic.Mechanisms.CRC.Press__411 Cholinesterase inhibitors stabilize cognitive decline in Alzheimer patients through beta-amyloid metabolism interaction.
Faria_2004_Cholinergic.Mechanisms.CRC.Press__571 Tetanic fade is revealed by blocking presynaptic nicotinic receptors containing alpha3beta2 subunits after reducing the safety fac.
Nachon_2004_Cholinergic.Mechanisms.CRC.Press__165 X-Ray structures of native and soman-aged human butyrylcholinesterase.
Bymaster_2004_Cholinergic.Mechanisms.CRC.Press__331 New evidence for the involvement of muscarinic cholinergic receptors in psychoses.
Giovannini_2004_Cholinergic.Mechanisms.CRC.Press__387 Activation of the cholinergic system during cognitive processes.
Grantham_2004_Cholinergic.Mechanisms.CRC.Press__575 Functional expression and stoichiometry of the novel human alpha9beta10 heteromeric nicotinic acetylcholine receptor.
Zhang_2004_Cholinergic.Mechanisms.CRC.Press__751 Neuroprotective effects of huperzine A and donepezil on staurosporine-induced injury in primary cortical neurons.
Parnas_2004_Cholinergic.Mechanisms.CRC.Press__99 The Ca-voltage hypothesis for neurotransmitter release ? current status.
Harel_2004_Cholinergic.Mechanisms.CRC.Press__183 Crystal structure of the tetramerization domain of acetylcholinesterase at 2.
Herholz_2004_Cholinergic.Mechanisms.CRC.Press__419 Measuring cerebral acetylcholine esterase activity in Alzheimer dementia by PET functional parametric imaging.
Hogg_2004_Cholinergic.Mechanisms.CRC.Press__591 alpha-Conotoxins PnIA and [A10L]PnIA stabilize different states of the chick neuronal alpha7 acetylcholine receptor.
Hrabovska_2004_Cholinergic.Mechanisms.CRC.Press__593 Acetylcholinesterase knockout mice have increased sensitivity to scopolamine and atropine.
Hulme_2004_Cholinergic.Mechanisms.CRC.Press__55 Structure and activation of muscarinic acetylcholine receptors.
Spreadbury_2004_Cholinergic.Mechanisms.CRC.Press__717 Calcium conductance and choline sensitivity of slow channel syndrome acetylcholine receptor mutants.
Bermudez_2004_Cholinergic.Mechanisms.CRC.Press__471 The agonist biphasic dose-response curve of human alpha4beta2 nicotinic acetylcholine receptors is influenced by Ca2+ ions and pho.
Israel_2004_Cholinergic.Mechanisms.CRC.Press__91 Acetylcholine- and glutamate-mediated transmission.
Myslivecek_2004_Cholinergic.Mechanisms.CRC.Press__653 Hydrocortisone affects the densities of cardiac muscarinic and adrenergic receptors.
Massoulie_2004_Cholinergic.Mechanisms.CRC.Press__155 Processing and anchoring of cholinesterases in muscle and brain.
Shi_2004_Cholinergic.Mechanisms.CRC.Press__695 Ligand-induced conformational changes in the omega loop of acetylcholinesterase revealed by fluorescence spectroscopy.
Klein_2004_Cholinergic.Mechanisms.CRC.Press__399 Conditions for a precursor control of acetylcholine release in mouse hippocampus.
Crayton_2004_Cholinergic.Mechanisms.CRC.Press__543 Combination donepezil and dihydroepiandrosterone therapy for post-stroke rehabilitation.
Jones_2004_Cholinergic.Mechanisms.CRC.Press__599 Nicotinic alpha4 receptor-mediated acetylcholine release from rat interpenduncular nucleus.
Stojan_2004_Cholinergic.Mechanisms.CRC.Press__721 Significance of parameters in various kinetic schemes for cholinesterases.
Tai_2004_Cholinergic.Mechanisms.CRC.Press__727 Mechanism of acetylcholinesterase inhibition by fasciculin.
Tsim_2004_Cholinergic.Mechanisms.CRC.Press__105 The role of P2Y1 nucleotide receptors in the formation and maintenance of the skeletal neuromuscular junctions.
Mis_2004_Cholinergic.Mechanisms.CRC.Press__641 mRNAs encoding acetylcholinesterase, butyrylcholinesterase and agrin 19 share the same temporal pattern of expression during development of rat spinal cord.
Loffelholz_2004_Cholinergic.Mechanisms.CRC.Press__395 How is the brain protected against excess choline concentrations?
Kotzyba-Hibert_2004_Cholinergic.Mechanisms.CRC.Press__607 Mapping the acetylcholine-binding sites of Torpedo nicotinic receptor using photoaffinity labeling.
Kubo_2004_Cholinergic.Mechanisms.CRC.Press__617 Identification and characterization of a diverse family of neurotoxin-like peptides from the South American coral snake.
Oliviera_2004_Cholinergic.Mechanisms.CRC.Press__655 Fine-tuning modulation of neuronal muscarinic M1 (facilitatory) and M2 (inhibitory) receptor activation by adenosine at the rat neuromuscular junction.
Li_2004_Cholinergic.Mechanisms.CRC.Press__619 Muscarinic acetylcholine receptors are down-regulated in acetylcholinesterase knockout mice.
Lintern_2004_Cholinergic.Mechanisms.CRC.Press__623 Altered activity of cholinergic enzymes in muscles and brain of the obese-diabetic (ob\/ob) mouse.
Berger_2004_Cholinergic.Mechanisms.CRC.Press__369 The effects of apoE3 and apoE4 on lipid synthesis and uptake.
Hersh_2004_Cholinergic.Mechanisms.CRC.Press__133 Regulation of cholinergic gene expression by NRSF\/REST.
Luttmann_2004_Cholinergic.Mechanisms.CRC.Press__631 Buprofezin and novaluron inhibit acetylcholinesterase activity in B-biotype Bemisia tabaci.
Battaglia_2004_Cholinergic.Mechanisms.CRC.Press__463 Human panic disorder and the cholinergic system.
Jevsek_2004_Cholinergic.Mechanisms.CRC.Press__597 Origin of acetylcholinesterase in the in vitro formed neuromuscular junction.
Weinstock_2004_Cholinergic.Mechanisms.CRC.Press__271 Sex differences in the actions of cholinesterase inhibitors.
Bunc_2004_Cholinergic.Mechanisms.CRC.Press__507 In vivo cholinergic effects in the rat of head-to-tail 3-alkylpiridinium polymers isolated from the marine sponge Reniera sarai.
Cottingham_2004_Cholinergic.Mechanisms.CRC.Press__535 A peptide from the C-terminal oligomerization domain of human synaptic (T-form) acetylcholinesterase forms classical amyloid fibrils.
Rischmueller_2004_Cholinergic.Mechanisms.CRC.Press__233 Muscarinic receptor autoantibodies in Sjogren?s syndrome.
Segal_2004_Cholinergic.Mechanisms.CRC.Press__405 Cholinergic neurons in culture.
Treinin_2004_Cholinergic.Mechanisms.CRC.Press__207 Genetic dissection of an acetylcholine receptor involved in neuronal degeneration.
Souroujon_2004_Cholinergic.Mechanisms.CRC.Press__241 Immunotherapy of myasthenia gravis.
Moore_2004_Cholinergic.Mechanisms.CRC.Press__649 Brain penetration and behavioral properties of a potent alpha7 nicotinic acetylcholine receptor agonist in the rat.
Moralev_2004_Cholinergic.Mechanisms.CRC.Press__645 New essential residues in the cholinesterase acyl pocket.
Youdim_2004_Cholinergic.Mechanisms.CRC.Press__353 PKC and MAP kinase-dependent processing of amyloid precursor protein (APP) by neuroprotective propargylamine cholinesterase inhibitors derived from rasagiline and nonsteroidal anti-inflammatory drugs.
Murray_2004_Cholinergic.Mechanisms.CRC.Press__651 Dopamine release from rat striatal slices in vitro and functional effects in 6-OHDA-treated rats in vivo are mediated by beta2 nicotinic acetylcholine receptors.
Javed_2004_Cholinergic.Mechanisms.CRC.Press__595 Investigating the diversity of acetylcholinesterase in insect species.
Neva_2004_Cholinergic.Mechanisms.CRC.Press__291 Acetylcholinesterase regulation in skeletal muscles.
Inestrosa_2004_Cholinergic.Mechanisms.CRC.Press__363 Neurodegenerative processes in Alzheimer?s disease.
Crawford_2004_Cholinergic.Mechanisms.CRC.Press__539 Identification of species differences in the pharmacology of the alpha-7 nicotinic receptor using the antagonist radioligand [3H]-methyllycaconitine.
Wang_2004_Cholinergic.Mechanisms.CRC.Press__317 Autonomic function of neuronal nicotinic acetylcholine receptor subunits alpha5, beta2 and beta4.
Perl_2004_Cholinergic.Mechanisms.CRC.Press__659 alpha7 Acetylcholine receptor mRNA in blood lymphocytes.
Taylor_2004_Cholinergic.Mechanisms.CRC.Press__81 Rene Couteaux Lecture.
Masson_2004_Cholinergic.Mechanisms.CRC.Press__637 Hysteresis in butyrylcholinesterase catalysis.
Salvaterra_2004_Cholinergic.Mechanisms.CRC.Press__193 Regulation of cholinergic neurotransmitter phenotypes.
Francis_2004_Cholinergic.Mechanisms.CRC.Press__431 The cholinergic system and cognitive and noncognitive behavioral dysfunction in Alzheimer?s disease.
Poveda_2004_Cholinergic.Mechanisms.CRC.Press__665 Segregation of phosphatidic acid-rich domains in reconstituted acetylcholine receptor membranes.
Pregelj_2004_Cholinergic.Mechanisms.CRC.Press__669 Muscle acetylcholinesterase expression in hyperthyreotic and hypothyreotic rats.
Henchman_2004_Cholinergic.Mechanisms.CRC.Press__589 Influence of water on the function of acetylcholinesterase.
Gordon_2004_Cholinergic.Mechanisms.CRC.Press__265 Polyurethane immobilized enzymes.
Robertson_2004_Cholinergic.Mechanisms.CRC.Press__381 Development of cholinergic projections to cortex.
Rossetto_2004_Cholinergic.Mechanisms.CRC.Press__681 Studies on the mechanism of blockade of acetylcholine release by snake presynaptic PLA2 neurotoxins.
Choi_2004_Cholinergic.Mechanisms.CRC.Press__515 NFKB regulates the promoter activity of human acetylcholinesterase in muscle.
Rozengart_2004_Cholinergic.Mechanisms.CRC.Press__685 Variability of substrate specificity in cholinesterases of vertebrates and invertebrates.
Zwart_2004_Cholinergic.Mechanisms.CRC.Press__309 Common structural and pharmacological properties of serotonin 5-HT3 receptors and alpha7 nicotinic acetylcholine receptors.
Rydberg_2004_Cholinergic.Mechanisms.CRC.Press__687 Overexpression of the extracellular and cytoplasmic domains of the Drosophila adhesion protein, gliotactin.
Fuchs_2004_Cholinergic.Mechanisms.CRC.Press__19 The binding site for alpha-bungarotoxin in the acetylcholine receptor.
Servent_2004_Cholinergic.Mechanisms.CRC.Press__27 Pharmacological and structural characterization of the interaction of snake toxins with nicotinic acetylcholine receptors.
Shafferman_2004_Cholinergic.Mechanisms.CRC.Press__245 A complex array of post-translation modifications determines the circulatory longevity of acetylcholinesterase in a hierarchical manner.
Tsuji_2004_Cholinergic.Mechanisms.CRC.Press__77 Rene Couteaux (1909-1999) and his presynaptic active zone.
Shoham_2004_Cholinergic.Mechanisms.CRC.Press__697 ?Readthrough? acetylcholinesterase and cholinergic neurotransmission.
Smulders_2004_Cholinergic.Mechanisms.CRC.Press__715 Effects of carbamate insecticides on rat neuronal alpha4beta4 nicotinic receptors and rat brain acetylcholinesterase.
Tucek_2004_Cholinergic.Mechanisms.CRC.Press__71 Roles of external loops of muscarinic receptors in interactions between N-methylscopolamine and allosteric modulators.
Evron_2004_Cholinergic.Mechanisms.CRC.Press__567 Transgenic manipulations of neuromuscular junction maintenance.
Teixeira_2004_Cholinergic.Mechanisms.CRC.Press__731 Probing the binding interface between the nicotinic acetylcholine receptor and a short alpha-neurotoxin through receptor-biotinyltoxin-streptavidin terary complex
Posayanonda_2004_Cholinergic.Mechanisms.CRC.Press__663 Effects of methomyl on cell cycle and apoptosis in leukocytic cells.
Mars_2004_Cholinergic.Mechanisms.CRC.Press__635 Formation of neuromuscular junctions in co-cultures of human muscle and rat embryonic spinal cord is accompanied by differentiation of neuronal and glial cells.
De Vente_2004_Cholinergic.Mechanisms.CRC.Press__551 NO-dependent and NO-independent cGMP synthesis in cortical cholinergic neurons of the rat brain.
Simeon-Rudolf_2004_Cholinergic.Mechanisms.CRC.Press__701 Comparison of two reaction schemes for the hydrolysis of acetylthiocholine by butyrylcholinesterase.
Bernard_2004_Cholinergic.Mechanisms.CRC.Press__477 Dramatic depletion of cell surface muscarinic receptor due to limited delivery from intracytoplasmic stores in neurons of acetylcholinesterase-deficient mice.
Roschchina_2004_Cholinergic.Mechanisms.CRC.Press__679 Plant cholinesterase activity as a biosensor.
Zhang_2004_Cholinergic.Mechanisms.CRC.Press__757 Cloning and characterization of the acetylcholinesterase gene in the chicken.
Xiao_2004_Cholinergic.Mechanisms.CRC.Press__733 Huperzine A, a promising anti-Alzheimer?s agent, reduces staurosporine-induced apoptosis in NG108-15 cells.
Yamanturk_2004_Cholinergic.Mechanisms.CRC.Press__739 Effects of lithium chloride on memory performances of mice in an elevated plus-maze test.
Yamanturk_2004_Cholinergic.Mechanisms.CRC.Press__741 Effects of 7-nitroindazole on memory performances of rats trained for a three-panel runway task.
Bogoch_2004_Cholinergic.Mechanisms.CRC.Press__137 Unveiling the molecular events leading to a neurotransmitter phenotype switch in developing neurons.
Zaninetti_2004_Cholinergic.Mechanisms.CRC.Press__745 Nicotinic cholinergic activation of magnocellular endocrine neurons of the hypothalamus.
Zeev-Ben-Mordehai_2004_Cholinergic.Mechanisms.CRC.Press__747 Use of the morphing graphics technique to visualize conformational differences between acetylcholinesterases from different species and inhibitor-induced conformational changes.
Pittel_2004_Cholinergic.Mechanisms.CRC.Press__345 Beta-amyloids, tau hyperphosphorylation and cognition are beneficially affected by M1 muscarinic agonists.
Grubic_2004_Cholinergic.Mechanisms.CRC.Press__113 Control of expression of nicotinic receptor and acetylcholinesterase in the developing neuromuscular junction in the human muscle.
Radic_2004_Cholinergic.Mechanisms.CRC.Press__171 Intrinsic tryptophan fluorescence of cholinesterases.
Zrinka_2004_Cholinergic.Mechanisms.CRC.Press__611 Phosphonylation of acetylcholinesterase and the propensity for reactivation analysed by chirality and mutagenesis.
Krejci_2004_J.Neurochem_91_88 Multiple promoters drive tissue-specific expression of the human M muscarinic acetylcholine receptor gene
Chernyavsky_2004_J.Cell.Sci_117_5665 Differential regulation of keratinocyte chemokinesis and chemotaxis through distinct nicotinic receptor subtypes
Chernyavsky_2004_J.Cell.Biol_166_261 Novel signaling pathways mediating reciprocal control of keratinocyte migration and wound epithelialization through M3 and M4 muscarinic receptors
Grando_2004_J.Investig.Dermatol.Symp.Proc_9_84 New approaches to the treatment of pemphigus
Kawashima_2004_Front.Biosci_9_2063 Expression of non-neuronal acetylcholine in lymphocytes and its contribution to the regulation of immune function
Nguyen_2004_J.Biol.Chem_279_2135 Pemphigus vulgaris IgG and methylprednisolone exhibit reciprocal effects on keratinocytes
Nguyen_2004_Exp.Cell.Res_294_534 Synergistic control of keratinocyte adhesion through muscarinic and nicotinic acetylcholine receptor subtypes
Suenaga_2004_Vascul.Pharmacol_41_51 Up-regulation of lymphocytic cholinergic activity by ONO-4819, a selective prostaglandin EP4 receptor agonist, in MOLT-3 human leukemic T cells
Suzuki_2004_Neurosci.Lett_356_57 Picrotoxin increased acetylcholine release from rat cultured embryonic septal neurons
Hilborn_2004_Arch.Environ.Health_59_467 A dried blood spot method to evaluate cholinesterase activity in young children
Padilla_2004_J.Toxicol.Environ.Health.A_67_1477 Further assessment of an in vitro screen that may help identify organophosphorus pesticides that are more acutely toxic to the young
Dubovy_2004_Anat.Sci.Int_79_198 Schwann cells and endoneurial extracellular matrix molecules as potential cues for sorting of regenerated axons: a review
Haninec_2004_Exp.Brain.Res_159_425 Reinnervation of the rat musculocutaneous nerve stump after its direct reconnection with the C5 spinal cord segment by the nerve graft following avulsion of the ventral spinal roots: a comparison of intrathecal administration of brain-derived neurotrophic factor and Cerebrolysin
Kubek_2004_Ann.Anat_186_231 Morphological evidence of collateral sprouting of intact afferent and motor axons of the rat ulnar nerve demonstrated by one type of tracer molecule
Bai_2004_Neuron_41_929 Fusion pore dynamics are regulated by synaptotagmin=t-SNARE interactions
Chen_2004_Biochemistry_43_10149 Mechanism-based discovery of small molecules that prevent noncompetitive inhibition by cocaine and MK-801 mediated by two different sites on the nicotinic acetylcholine receptor
Chevessier_2004_Neuromuscul.Disord_14_208 Tubular aggregates are from whole sarcoplasmic reticulum origin: alterations in calcium binding protein expression in mouse skeletal muscle during aging
Cui_2004_J.Membr.Biol_202_137 Selection of 2'-fluoro-modified RNA aptamers for alleviation of cocaine and MK-801 inhibition of the nicotinic acetylcholine receptor
Donald_2004_Comp.Biochem.Physiol.A.Mol.Integr.Physiol_137_21 Vasodilator mechanisms in the dorsal aorta of the giant shovelnose ray, Rhinobatus typus (Rajiformes\; Rhinobatidae)
Dresbach_2004_Mol.Cell.Neurosci_27_227 Synaptic targeting of neuroligin is independent of neurexin and SAP90\/PSD95 binding
Govindasamy_2004_J.Struct.Biol_148_226 Structural insights and functional implications of choline acetyltransferase
Krivoshein_2004_Biochemistry_43_481 Mechanism-based approach to the successful prevention of cocaine inhibition of the neuronal (alpha 3 beta 4) nicotinic acetylcholine receptor
Lecchi_2004_Neuroreport_15_307 Ganglion cells from chick retina display multiple functional nAChR subtypes
Lian_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_374 Crystallization and preliminary X-ray crystallographic studies on recombinant rat choline acetyltransferase
Lindell_2004_Bioorg.Med.Chem.Lett_14_511 The design and synthesis of novel inhibitors of NADH:ubiquinone oxidoreductase
Llinas_2004_Proc.Natl.Acad.Sci.U.S.A_101_17855 Vesicular reuptake inhibition by a synaptotagmin I C2B domain antibody at the squid giant synapse
Marie_2004_Neuron_43_207 Dap160\/intersectin scaffolds the periactive zone to achieve high-fidelity endocytosis and normal synaptic growth
Marrs_2004_Toxicol.Rev_23_145 The role of diazepam in the treatment of nerve agent poisoning in a civilian population
Matveev_2004_Biophys.J_86_2691 Facilitation through buffer saturation: constraints on endogenous buffering properties
Sekine-Aizawa_2004_Proc.Natl.Acad.Sci.U.S.A_101_17114 Imaging of receptor trafficking by using alpha-bungarotoxin-binding-site-tagged receptors
Wang_2004_J.Neurophysiol_91_1596 Photolysis of postsynaptic caged Ca2+ can potentiate and depress mossy fiber synaptic responses in rat hippocampal CA3 pyramidal neurons
Wehner_2004_Neurosci_129_11 Role of neuronal nicotinic receptors in the effects of nicotine and ethanol on contextual fear conditioning
Zhong_2004_J.Neurosci_24_4205 Roles of Ca2+, hyperpolarization and cyclic nucleotide-activated channel activation, and actin in temporal synaptic tagging
Massoulie_2004_7th.ChE.Meeting.Pucon__1 Molecular organization and functional localization of acetylcholinesterase
Jevsek_2004_7th.ChE.Meeting.Pucon__7 Expression of acetylcholinesterase in the developing neuromuscular junction in the in vitro innervated human muscle
Pregelj_2004_7th.ChE.Meeting.Pucon__15 Factors determining acetylcholinesterase expression in skeletal muscles
Minic_2004_7th.ChE.Meeting.Pucon__19 Synaptic transmission at AChE\/- and CoIQ-I-knockout mouse neuromuscular junctions
Deschenes-Furry_2004_7th.ChE.Meeting.Pucon__25 Neurotrophins regulate acetylcholinesterase expression in neurons via post-transcriptional mechanisms
Aldunate_2004_7th.ChE.Meeting.Pucon__31 Nerve-induced muscle activity modulates CGRP effect on AChE expression in rat myotubes
Camp_2004_7th.ChE.Meeting.Pucon__43 Knockout mice with deletions of alternatively spliced exons of acetylcholinesterase
Krejci_2004_7th.ChE.Meeting.Pucon__49 PRiMA: The anchor domain of brain AChE
Augusti-Tocco_2004_7th.ChE.Meeting.Pucon__55 Alternative AChE molecular forms exhibit similar ability to induce neurite outgrowth in transfectcd neuroblastoma clones
Arpagaus_2004_7th.ChE.Meeting.Pucon__61 Four acetylcholinesterase genes in the nematode Caenorhabditis elegans: Gene structure and molecular forms
Sklan_2004_7th.ChE.Meeting.Pucon__65 Interaction of readthrough acetylcholinesterase with the PKC scaffold protein Rackl facilitates antisense-suppressible contextual fear responses
Chatonnet_2004_7th.ChE.Meeting.Pucon__75 Evolution of the Carboxylcsterase_b (CO esterase) family: The closest relatives of choIinesterases among alpha\/beta hydrolase fold family. hypothesis of horizontal transfer from eucaryotes to bacteria
Giacobini_2004_7th.ChE.Meeting.Pucon__81 New indications for cholinesterase inhibitor therapy
Rakonczay_2004_7th.ChE.Meeting.Pucon__89 Cholinesterase inhibitors are not all alike
Inestrosa_2004_7th.ChE.Meeting.Pucon__95 Neurodegenerative processes in Alzheimer's disease: Role of A-beta-AChE complexes and Wnt signaling
Small_2004_7th.ChE.Meeting.Pucon__103 A-beta induces specific glycoforms of acetylcholinesterase and butyrylcholinesterase in Alzheimer's disease brain
Cottingham_2004_7th.ChE.Meeting.Pucon__109 A fragment of the AChE T-peptide forms amyloid fibrils: Antibodies raised against the fibrillogenic fragment and the full-length T -peptide
Brimijoin_2004_7th.ChE.Meeting.Pucon__115 Acetylcholinesterase expression and the formation of amyloid plaques in a transgenic mouse model of Alzheimer's disease
Chacon_2004_7th.ChE.Meeting.Pucon__119 Effects of intrahippocampal injection of acetylcholinesterase-A-beta complexes and AChE alone: Analysis of neuropathological changes and spatial learning acquisition
Greenfield_2004_7th.ChE.Meeting.Pucon__127 The role in neurodegeneration of a peptide derived from AChE
Godoy_2004_7th.ChE.Meeting.Pucon__135 The anti-inflammatory bifunctional compound IBU-PO protects rat hippocampal neurons from A-beta-induced cytotoxicity and beta-catenin depletion
Morgan_2004_7th.ChE.Meeting.Pucon__141 Acetylcholinesterase stabilizes beta-amyloid fibrils against disassembly induced by laminin
Alvarez_2004_7th.ChE.Meeting.Pucon__147 The association of AChE to A-beta peptide aggregates increases its neurotoxicity
Von Bernhardi_2004_7th.ChE.Meeting.Pucon__153 Increased detection of amyloid precursor protein in astrocytes exposed to acetylcholinesterase in culture
Von Bernhardi_2004_7th.ChE.Meeting.Pucon__159 Decreased cholinesterase activity in blood cells of Alzheimer's disease patients
Villalon_2004_7th.ChE.Meeting.Pucon__165 Acetylcholinesterase-rich neurons in the cerebral cortex of the rodent Octodon degus
Nigam_2004_7th.ChE.Meeting.Pucon__171 Interaction of beta-amyloid and cholinesterases by fluorescent polarization
Taylor_2004_7th.ChE.Meeting.Pucon__177 Spectroscopic approaches to the study of acetylcholinesterase structure and function
Shafferman_2004_7th.ChE.Meeting.Pucon__181 The aromatic trapping of histidine 447 in catalysis of acetylcholinesterases
Reiner_2004_7th.ChE.Meeting.Pucon__187 Kinetics of ethopropazine binding to butyrylcholinesterase in the absence and presence of acetylthiocholine
Masson_2004_7th.ChE.Meeting.Pucon__191 Hysteretic behavior of butyrylcholinesterase: Kinetic curiosity or catalytically and physiologicaly significant?
Radic_2004_7th.ChE.Meeting.Pucon__201 Monitoring cholinesterase - ligand interactions
Bui_2004_7th.ChE.Meeting.Pucon__207 The displacement of ligand through the bottleneck region of the acetylcholinesterase gorge
Johnson_2004_7th.ChE.Meeting.Pucon__213 Substrate activation with a cationic acetanilide substrate in human acetylcholinesterase
Kovarik_2004_7th.ChE.Meeting.Pucon__219 Phosphorylation of mouse cholinesterases and mutants by DDVP and reactivation of conjugates by HI-6 and 2-PAM
Pezzementi_2004_7th.ChE.Meeting.Pucon__223 Amino acids involved in substrate and inhibitor specificity of cholinesterase 2 from Amphioxus
Shi_2004_7th.ChE.Meeting.Pucon__225 Analysis of acetylcholinesterase structure and dynamics by steady state and time-resolved fluorescence
Toutant_2004_7th.ChE.Meeting.Pucon__233 New biosensors for improved detection of environmental and food contamination by anticholinesterase pesticides
Shi_2004_7th.ChE.Meeting.Pucon__237 Engineering of acetylcholinesterase for insecticide detection: example of Aldicarbe
Gordon_2004_7th.ChE.Meeting.Pucon__243 Detection and identification of chemical warfare Agents polyurethane immobilized enzymes
Luo_2004_7th.ChE.Meeting.Pucon__251 Strategy for reactivation of organophosphate-inhibited human butyrylcholinesterase
Jennings_2004_7th.ChE.Meeting.Pucon__265 Organophosphate modifications of mouse acetylcholinesterase: Detection of exposure by Maldi-Tof mass spectrometry
Saxena_2004_7th.ChE.Meeting.Pucon__269 Human serum butyrylcholinesterase: A future generation antidote for organophosphate chemical warfare agent toxicity .
Loudwig_2004_7th.ChE.Meeting.Pucon__277 Photoreversible inhibitions of cholinesterases
Samson_2004_7th.ChE.Meeting.Pucon__285 Interactions of toxins with cholinergic proteins
Bigbee_2004_7th.ChE.Meeting.Pucon__295 Mechanisms underlying the axonal growth promoting property of acetylcholinesterase
Duysen_2004_7th.ChE.Meeting.Pucon__301 Helicobacter hepaticus infection in acetylcholinesterase knockout mice results in severe intestinal distension
Pregelj_2004_7th.ChE.Meeting.Pucon__309 Phasic muscle activation pattern and calcineurin inhibition increase acetylcholinesterase expression in the slow soleus muscle of the Rat
Hrabovska_2004_7th.ChE.Meeting.Pucon__315 Acetylcholinesterase wild-type and knockout mice show different locomotor activity after scopolamine injection
Alonso_2004_Chem.Commun.(Camb)__412 Generation of strong, homochiral bases by electrochemical reduction of phenazine derivatives
Lukomskaya_2004_Neurosci.Behav.Physiol_34_181 Comparison of the anticonvulsive activities of organic mono- and dications with their abilities to inhibit NMDA and AMPA glutamate receptors
Lukomskaya_2004_Neurosci.Behav.Physiol_34_783 Studies of the roles of NMDA and AMPA glutamate receptors in the mechanism of corasole convulsions in mice
Mesulam_2004_7th.ChE.Meeting.Pucon__321 Poster (1) Cholinesterases in health and disease
Massoulie_2004_7th.ChE.Meeting.Pucon__321 Poster (2) Molecular organization and functional localization of acetylcholinesterase
Anglister_2004_7th.ChE.Meeting.Pucon__322 Poster (3) Fine localization of acetylcholinesterase at the neuromuscular junctions
Mis_2004_7th.ChE.Meeting.Pucon__323 Poster (4) Expression of AChE at the developing neuromuscular junction in human skeletal muscle in vitro.
Rotundo_2004_7th.ChE.Meeting.Pucon__323 Poster (5) Organizing acetylcholinesterase molecules at the neuromuscular junction.
Sketelj_2004_7th.ChE.Meeting.Pucon__324 Poster (6) Factors determining acetylcholinesterase expression in skeletal muscles.
Minic_2004_7th.ChE.Meeting.Pucon__324 Poster (7) Synaptic transmission at AChE-\/- and ColQ knockout mouse neuromuscular junctions
Rossi_2004_7th.ChE.Meeting.Pucon__325 Poster (8) AChE mRNA transcription during avian muscle development and its regulation by membrane depolarization.
Jasmin_2004_7th.ChE.Meeting.Pucon__325 Poster (9) Transcriptional and post-transcriptional mechanisms regulate AChE mRNA expression in skeletal muscle and neurons
Camp_2004_7th.ChE.Meeting.Pucon__326 Poster (10) Knockout mice with deletions of alternatively spliced exons of acetylcholinesterase.
Krejci_2004_7th.ChE.Meeting.Pucon__326 Poster (11) PRiMA, the anchor domain of brain AChE
Taylor_2004_7th.ChE.Meeting.Pucon__327 Poster (13) Conformational dynamics accompanying substrate and inhibitor binding to acetylcholinesterase.
Shafferman_2004_7th.ChE.Meeting.Pucon__327 Poster (14) The aromatic trapping of histidine 447 in catalysis of acetylcholinesterases
Moussavi-Harami_2004_7th.ChE.Meeting.Pucon__328 Poster (15) Molecular recognition in AChE catalysis - the view from near and far.
Johnson_2004_7th.ChE.Meeting.Pucon__328 Poster (16) Ligand interactions within the active site of acetylcholinesterase
Kovach_2004_7th.ChE.Meeting.Pucon__329 Poster (17) Short, strong hydrogen bonds at the active site of cholinesterases: H-NMR studies.
Weiner_2004_7th.ChE.Meeting.Pucon__330 Poster (18) Partially unfolded states of acetylcholinesterase: rule or exception?
Reiner_2004_7th.ChE.Meeting.Pucon__330 Poster (19) Kinetics of ethopropazine binding to butyrylcholinesterase in the absence and presence of acetylthiocholine.
Masson_2004_7th.ChE.Meeting.Pucon__331 Poster (20) Hysteretic behavior of butyrylcholinesterase : kinetic curiosity or catalytically and physiologically significant?
Ordentlich_2004_7th.ChE.Meeting.Pucon__332 Poster (21) Analysis of acetylcholinesterase adducts of alzheimer's drugs
Radic_2004_7th.ChE.Meeting.Pucon__332 Poster (22) Monitoring cholinesterase-ligand interactions
Barak_2004_7th.ChE.Meeting.Pucon__332 Poster (23) Phosphorylation and aging of AChE - insights from mutagenesis, mass spectrometry and structural studies
Toutant_2004_7th.ChE.Meeting.Pucon__333 Poster (24) New biosensors for improved detection of environmental contamination by anticholinesterase pesticides
Fournier_2004_7th.ChE.Meeting.Pucon__334 Poster (25) Acetylcholinesterase engineering for detection of insecticide residues.
Marty_2004_7th.ChE.Meeting.Pucon__334 Poster (26) Strategy for the development of biosensors based on bio-engineered acetylcholinesterases.
Combes_2004_7th.ChE.Meeting.Pucon__334 Poster (27) Structure of the four acetylcholinesterase genes in the nematode caenorhabditis elegans.
Raymond_2004_7th.ChE.Meeting.Pucon__335 Poster (28) Two genes code for acetylcholinesterase in insects.
Moores_2004_7th.ChE.Meeting.Pucon__335 Poster (29) Insecticide-insensitive AChE in myzus persicae - a tale of two genes.
Gordon_2004_7th.ChE.Meeting.Pucon__336 Poster (30) Detection and identification of chemical warfare agents polyurethane immobilized enzymes
Sussman_2004_7th.ChE.Meeting.Pucon__337 Poster (31) Natively unstructured proteins: a case study of cholinesterase-like adhesion molecules (clams)
Doctor_2004_7th.ChE.Meeting.Pucon__337 Poster (32) Bioscavengers: antidotes for organophosphate chemical warfare agent toxicity.
Luo_2004_7th.ChE.Meeting.Pucon__338 Poster (33) Strategy for the reactivation of organophosphate-inhibited human butyrylcholinesterase
Ashani_2004_7th.ChE.Meeting.Pucon__338 Poster (34) Interaction of drugs and environmental factors with bioscavengers: does fluoride in human plasma affect the antidotal properties of human butyrylcholinesterase?
Velan_2004_7th.ChE.Meeting.Pucon__339 Poster (35) The hierarchy of post-translation modifications determining circulatory longevity of acetylcholinesterase.
Saxena_2004_7th.ChE.Meeting.Pucon__339 Poster (36) Human serum butyrylcholinesterase: a future generation antidote for organophosphate chemical warfare agent toxicity
Soreq_2004_7th.ChE.Meeting.Pucon__340 Poster (37) Multileveled regulation of acetylcholinesterase gene expression under impaired cholinergic homeostasis.
Giacobini_2004_7th.ChE.Meeting.Pucon__340 Poster (38) Do cholinesterase inhibitors affect beta-amyloid metabolism in alzheimer patients?
Lahiri_2004_7th.ChE.Meeting.Pucon__341 Poster (39) A new generation of cholinesterase inhibitors with amyloid-modifying properties.
De Ferrari_2004_7th.ChE.Meeting.Pucon__342 Poster (40) Acetylcholinesterase - amyloid beta-peptide interaction.
Rakonczay_2004_7th.ChE.Meeting.Pucon__342 Poster (41) Cholinesterase inhibitors are not all alike.
Fodero_2004_7th.ChE.Meeting.Pucon__342 Poster (42) The beta-amyloid protein induces unusual glycoforms of acetylcholinesterase and butyrylcholinesterase in the alzheimer's disease brain
Greig_2004_7th.ChE.Meeting.Pucon__343 Poster (43) BChE inhibition as a treatment strategy for alzheimer's disease.
Greenfield_2004_7th.ChE.Meeting.Pucon__344 Poster (44) The role in neurodegeneration of a peptide derived from acetylcholinesterase.
Bigbee_2004_7th.ChE.Meeting.Pucon__344 Poster (45) Mechanisms underlying the morphogenic properties of acetylcholinesterase
Fisher_2004_7th.ChE.Meeting.Pucon__345 Poster (46) Major hallmarks in alzheimer's disease (ad) can beneficially be modulated by M1 muscarinic agonists - an added value vs. cholinesterase inhibitors
Silman_2004_7th.ChE.Meeting.Pucon__346 Poster (47) Conformational plasticity of acetylcholinesterase
Harel_2004_7th.ChE.Meeting.Pucon__347 Poster (48) Crystal structure of the tetramerization domain of acetylcholinesterase reveals a model of the AChE tetramer
Nicolet_2004_7th.ChE.Meeting.Pucon__347 Poster (49) Crystallographic basis for substrate\/product exchange in cholinesterases.
Bourne_2004_7th.ChE.Meeting.Pucon__347 Poster (50) Insights into the interactions at the acetylcholinesterase peripheral anionic site.
Bourne_2004_7th.ChE.Meeting.Pucon__348 Poster (51) Novel compounds with distinctive interactions at the acetylcholinesterase peripheral anionic site
Loudwig_2004_7th.ChE.Meeting.Pucon__348 Poster (52) Photo-reversible inhibitions of cholinesterases
Samson_2004_7th.ChE.Meeting.Pucon__349 Poster (53) Interaction of toxins with cholinergic proteins.
Weik_2004_7th.ChE.Meeting.Pucon__349 Poster (54) Experimental approaches to study the dynamics of cholinesterases.
Lockridge_2004_7th.ChE.Meeting.Pucon__350 Poster (55) Life without acetylcholinesterase
Amitai_2004_7th.ChE.Meeting.Pucon__350 Poster (56) The bifunctional compound IBU-PO elicits prolonged anti-inflammatory and cholinesterase inhibition in vivo
Youdim_2004_7th.ChE.Meeting.Pucon__351 Poster (57) A novel neuroprotective trifunctional cholinesterase inhibitor derivative of the antiparkinson drug, rasagiline, for treatment of dementia and lewy body disease co-morbid with depression
Brimijoin_2004_7th.ChE.Meeting.Pucon__352 Poster (58) Acetylcholinesterase promotes amyloid plaques in transgenic mouse brain.
Bytyqi_2004_7th.ChE.Meeting.Pucon__352 Poster (59) Complete postnatal degeneration of the photoreceptor layer in an AChE knockout mouse
Bytyqi_2004_7th.ChE.Meeting.Pucon__353 Poster (60) Early distortion of network formation in the inner retina of an AChE knockout mouse
Aldunate_2004_7th.ChE.Meeting.Pucon__ Poster (61) Nerve-induced muscle activity modulates cgrp effect on AChE expression in rat myotubes
Allebrandt_2004_7th.ChE.Meeting.Pucon__354 Poster (62) Aryl acylamidase activity of in vitro expressed human butyrylcholinesterase
Alvarez_2004_7th.ChE.Meeting.Pucon__354 Poster (63) The association of acetylcholinesterase to amyloid-beta-peptide aggregates increases jt~ neurotoxicity
Amitai_2004_7th.ChE.Meeting.Pucon__354 Poster (64) Chloroperoxidases catalyzes the degradation of VX and sulfur mustard.
Andrews_2004_7th.ChE.Meeting.Pucon__355 Poster (65) A single amino acid substitution found in pirimicarb-insensitive acetylcholinesterase (AChE) of the peach-potato aphid, Myzus persicae (sulz.)
Augusti-Tocco_2004_7th.ChE.Meeting.Pucon__356 Poster (67) Cell surface expression of a GPi-anchored isoform of mouse acetylcholinesterase in klpmri!)' cells of kluyveromyces lactis.
Belbeoc'h_2004_7th.ChE.Meeting.Pucon__356 Poster (68) Oligomerization of acetylcholinesterase T blocks its degradation via the ubiquitin-proteasome pathway, by masking the c-terminal hydrophobic peptide.
Bui_2004_7th.ChE.Meeting.Pucon__357 Poster (69) The dynamics of ligand barrier-crossing transitions inside. the acetylcholinesterase gorge
Cabello_2004_7th.ChE.Meeting.Pucon__357 Poster (70) Malathion and parathion action site in the mammary gland cells
Chacon_2004_7th.ChE.Meeting.Pucon__357 Poster (71) Acetylcholinesterase induces neuronal loss and spatial memory deficits in mammalian hippocampus
Chatonnet_2004_7th.ChE.Meeting.Pucon__358 Poster (72) Evolution of the Carboxylesterase_B family
Chatonnet_2004_7th.ChE.Meeting.Pucon__359 Poster (73) Respiratory survival mechanisms in acetylcholinesterase knockout mice.
Colletier_2004_7th.ChE.Meeting.Pucon__359 Poster (74) Structural studies on torpedo californica acetylcholinesterase in complex with a substrate analogue
Cottingham_2004_7th.ChE.Meeting.Pucon__360 Poster (75) A fragment of the AChE t-peptide forms amyloid fibrils: antibodies raised against the fibrillogenic fragment and the full-length t-peptide
Cusack_2004_7th.ChE.Meeting.Pucon__360 Poster (76) Modulation of acetylcholinesterase kinetics employing ligands tethered to the mutant H287C: a model for organophosphate inhibitor desin
Dinamarca_2004_7th.ChE.Meeting.Pucon__361 Poster (77) Galanthamine inhibits the aggregation of the amyloid-beta-peptide stimulated by acetylcholinesterase in vitro.
Duysen_2004_7th.ChE.Meeting.Pucon__362 Poster (78) H. hepaticus infection in acetylcholinesterase knockout mice results in severe intestinal distension.
Dvir_2004_7th.ChE.Meeting.Pucon__362 Poster (79) X-ray structures of TcAChE complexed with (+)-huperzine a and (-)-huperzine b: structural evidence for an active-site rearrangement
Godoy_2004_7th.ChE.Meeting.Pucon__363 Poster (80) The anti-inflammatory-cholinergic bifunctional compound ibu-po protects at sub-micromolar levels rat hippocampal cells from a beta-induced apoptosis and beta-catenin depletion
Nigam_2004_7th.ChE.Meeting.Pucon__363 Poster (81) Interaction of beta-amyloid and cholinesterases by fluorescent polarization
Hrabovska_2004_7th.ChE.Meeting.Pucon__364 Poster (82) Acetylcholinesterase wild-type and knock-out mice show different locomotor activity after scopolamine injection
Hussein_2004_7th.ChE.Meeting.Pucon__364 Poster (83) Suppression of nematode acetylcholinesterase synthesis by RNA interference
Javed_2004_7th.ChE.Meeting.Pucon__365 Poster (84) Investigating the diversity of AChE in insect species
Jennings_2004_7th.ChE.Meeting.Pucon__365 Poster (85) Organophosphate modifications of mouse acetylcholinesterase: detection of exposure by maldi-tof mass spectrometry
Jevsek_2004_7th.ChE.Meeting.Pucon__366 Poster (86) Human muscle forms functional neuromuscular junctions in cocultures with the embryonic spinal cord explants of rat, mouse and human
Johnson_2004_7th.ChE.Meeting.Pucon__366 Poster (87) Ligand interactions within the active site of acetylcholinesterase
Kimbell_2004_7th.ChE.Meeting.Pucon__367 Poster (88) Analysis of human collagenic tailed acetylcholinesterase binding to the frog neuromuscular junction and to perlecan
Kovarik_2004_7th.ChE.Meeting.Pucon__367 Poster (89) Phosphorylation of mouse cholinesterases and mutants by ddvp and reactivation of conjugates by Hi-6 and 2-PAM
Li_2004_7th.ChE.Meeting.Pucon__368 Poster (90) Acetylcholinesterase knockout mice are resistant oxotremorine-induced hypothermia and pilocarpine-induced seizures
Morgan_2004_7th.ChE.Meeting.Pucon__369 Poster (92) Acetylcholinesterase stabilizes amyloid fibrils against disassembly induced by laminin
Nachon_2004_7th.ChE.Meeting.Pucon__369 Poster (93) How do the crystal structures of human butyrylcholinesterase compare to torpedo californica acetylcholinesterases structures?
Perrier_2004_7th.ChE.Meeting.Pucon__370 Poster (94) AChE and PRiMA mRNA expression in the mouse brain
Pezzementi_2004_7th.ChE.Meeting.Pucon__370 Poster (95) Amino acids involved in substrate and inhibitor specificity of cholinesterase 2 from Amphioxus
Pregelj_2004_7th.ChE.Meeting.Pucon_371_ Poster (96) The role of muscle activation pattern and calcineurin in acetylcholinesterase regulation in rat skeletal muscles
Rakonczay_2004_7th.ChE.Meeting.Pucon__371 Poster (97) Increased serum butyrylcholinesterase activity in type iib hyperlipidaemic patients
Robertson_2004_7th.ChE.Meeting.Pucon__372 Poster (98) Development of acetylcholinesterase-positive cholinergic projections to hippocampus and cingulate cortex: role of neurotrophins
Gaeta_2004_7th.ChE.Meeting.Pucon__372 Poster (99) Rational design, synthesis and pharmacological evaluation of novel, selective and highly potent cholinesterase inhibitors
Kichenin_2004_7th.ChE.Meeting.Pucon__373 Poster (100) Modification of muscarinic acetylcholine receptor expression in mucosal lymphoid tissues of rodents infected with Nippostrongylus brasiliensis
Villalon_2004_7th.ChE.Meeting.Pucon__373 Poster (101) Acetylcholinesterase-rich neurons in the cerebral cortex of Octodon degus.
von Bernhardi_2004_7th.ChE.Meeting.Pucon__373 Poster (102) Blood cells cholinesterase activity and dementia: decreased activity is established from early stages in alzheimer's disease and is common to various organic dementias
von Bernhardi_2004_7th.ChE.Meeting.Pucon__374 Poster (103) Acetylcholinesterase induces the expression of the beta-amyloid precursor protein in astrocytes and activates glial cells in culture
Zeev-Ben-Mordehai_2004_7th.ChE.Meeting.Pucon__375 Poster (104) Biophysical and bioinformatic analysis of the cytoplasmic portion of gliotactin
Shi_2004_7th.ChE.Meeting.Pucon__375 Poster (105) Analysis of acetylcholinesterase structure and dynamics by steady state and time-resolved fluorescence
Bon_2004_7th.ChE.Meeting.Pucon__376 Poster (106) Organization and properties of the C-terminal T (WAT) peptide of acetylcholinesterase C-terminal trimerisation domain (CDT) of collagen ColQ
Jimenez-Diaz_2004_J.Neurosci_24_9138 Role of cerebellar interpositus nucleus in the genesis and control of reflex and conditioned eyelid responses
Navarro-Lopez_2004_J.Neurosci_24_5109 A cholinergic synaptically triggered event participates in the generation of persistent activity necessary for eye fixation
Fournier_2004_Neurosci_123_785 Cortical acetylcholine release and electroencephalogram activation evoked by ionotropic glutamate receptor agonists in the rat basal forebrain
Fournier_2004_Neurosci_126_257 Modality- and region-specific acetylcholine release in the rat neocortex
Jones_2004_Prog.Brain.Res_145_157 Activity, modulation and role of basal forebrain cholinergic neurons innervating the cerebral cortex
Jones_2004_Arch.Ital.Biol_142_379 Paradoxical REM sleep promoting and permitting neuronal networks
Lee_2004_J.Neurophysiol_92_1182 Sleep-wake related discharge properties of basal forebrain neurons recorded with micropipettes in head-fixed rats
Modirrousta_2004_Neurosci_129_803 Gabaergic neurons with alpha2-adrenergic receptors in basal forebrain and preoptic area express c-Fos during sleep
Saint-Mleux_2004_J.Neurosci_24_63 Nicotinic enhancement of the noradrenergic inhibition of sleep-promoting neurons in the ventrolateral preoptic area
Steriade_2004_Prog.Brain.Res_145_179 Acetylcholine systems and rhythmic activities during the waking--sleep cycle
Aztiria_2004_J.Comp.Neurol_480_378 Alpha7 but not alpha4 AChR subunit expression is regulated by light in developing primary visual cortex
Brogdon_2004_J.Agromedicine_9_329 Insecticide resistance and vector control
Caldarone_2004_Biol.Psychiatry_56_657 High-affinity nicotinic acetylcholine receptors are required for antidepressant effects of amitriptyline on behavior and hippocampal cell proliferation
Dani_2004_Bioorg.Med.Chem.Lett_14_1837 Potential applications of nicotinic ligands in the laboratory and clinic
Gomez-Casati_2004_J.Assoc.Res.Otolaryngol_5_261 Linopirdine blocks alpha9alpha10-containing nicotinic cholinergic receptors of cochlear hair cells
Jones_2004_J.Neurosci.Methods_134_65 Alpha bungarotoxin-1.4 nm gold: a novel conjugate for visualising the precise subcellular distribution of alpha 7* nicotinic acetylcholine receptors
Jones_2004_J.Neurosci_24_11244 Precise localization of alpha7 nicotinic acetylcholine receptors on glutamatergic axon terminals in the rat ventral tegmental area
Katz_2004_J.Neurosci_24_7814 Developmental regulation of nicotinic synapses on cochlear inner hair cells
King_2004_Neuropharmacol_47 Suppl 1_132 Beta2-subunit-containing nicotinic acetylcholine receptors are critical for dopamine-dependent locomotor activation following repeated nicotine administration
Moretti_2004_Mol.Pharmacol_66_85 Nicotinic acetylcholine receptor subtypes expression during rat retina development and their regulation by visual experience
Pallavicini_2004_Bioorg.Med.Chem.Lett_14_5827 Synthesis and alpha4beta2 nicotinic affinity of 2-pyrrolidinylmethoxyimines and prolinal oxime ethers
Pidoplichko_2004_Learn.Mem_11_60 Nicotinic cholinergic synaptic mechanisms in the ventral tegmental area contribute to nicotine addiction
Talmage_2004_J.Comp.Neurol_472_134 Multiple personalities of neuregulin gene family members
Tsuneki_2004_Mol.Pharmacol_66_1061 Alkaloids indolizidine 235B', quinolizidine 1-epi-207I, and the tricyclic 205B are potent and selective noncompetitive inhibitors of nicotinic acetylcholine receptors
Weill_2004_Curr.Biol_14_R552 Insecticide resistance: a silent base prediction
Bell_2004_J.Neurochem_91_349 MAPK recruitment by beta-amyloid in organotypic hippocampal slice cultures depends on physical state and exposure time
Carroll_2004_J.Med.Chem_47_4588 Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues. Novel nicotinic antagonist
Centeno_2004_Brain.Res_1012_1 Expression of alpha 4 and alpha 7 nicotinic receptors in the brainstem of female rabbits after coitus
Christianson_2004_EMBO.J_23_4156 Regulation of nicotinic receptor expression by the ubiquitin-proteasome system
Clarke_2004_Prog.Brain.Res_145_253 Nicotinic modulation of thalamocortical neurotransmission
Culetto_2004_J.Biol.Chem_279_42476 The Caenorhabditis elegans unc-63 gene encodes a levamisole-sensitive nicotinic acetylcholine receptor alpha subunit
daCosta_2004_J.Biol.Chem_279_14967 Phosphatidic acid and phosphatidylserine have distinct structural and functional interactions with the nicotinic acetylcholine receptor
Damaj_2004_Mol.Pharmacol_66_675 Enantioselective effects of hydroxy metabolites of bupropion on behavior and on function of monoamine transporters and nicotinic receptors
Damaj_2004_Brain.Res_1024_146 Intrathecal CART (55-102) enhances the spinal analgesic actions of morphine in mice
Dogruer_2004_Bioorg.Med.Chem.Lett_14_523 3-(4-Aminobutyn-1-yl)pyridines: binding at alpha 4 beta 2 nicotinic cholinergic receptors
Drisdel_2004_Biotechniques_36_276 Labeling and quantifying sites of protein palmitoylation
Drisdel_2004_J.Neurosci_24_10502 The role of palmitoylation in functional expression of nicotinic alpha7 receptors
Dukat_2004_Bioorg.Med.Chem.Lett_14_3651 (+\/-)8-Amino-5,6,7,8-tetrahydroisoquinolines as novel antinociceptive agents
Ihara_2004_Biosci.Biotechnol.Biochem_68_761 Super agonist actions of clothianidin and related compounds on the SAD beta 2 nicotinic acetylcholine receptor expressed in Xenopus laevis oocytes
McIntosh_2004_Mol.Pharmacol_65_944 Analogs of alpha-conotoxin MII are selective for alpha6-containing nicotinic acetylcholine receptors
Parker_2004_Mol.Pharmacol_65_611 Up-regulation of brain nicotinic acetylcholine receptors in the rat during long-term self-administration of nicotine: disproportionate increase of the alpha6 subunit
Proskocil_2004_Endocrinology_145_2498 Acetylcholine is an autocrine or paracrine hormone synthesized and secreted by airway bronchial epithelial cells
Rayes_2004_J.Biol.Chem_279_36372 Molecular basis of the differential sensitivity of nematode and mammalian muscle to the anthelmintic agent levamisole
Rice_2004_Nat.Neurosci_7_583 Nicotine amplifies reward-related dopamine signals in striatum
Salmon_2004_Neurosci.Lett_360_73 Reduction of withdrawal signs after chronic nicotine exposure of alpha-calcitonin gene-related peptide knock-out mice
Sekhon_2004_Eur.Respir.J_23_906 Prenatal nicotine exposure increases connective tissue expression in foetal monkey pulmonary vessels
Shimomura_2004_Neurosci.Lett_363_195 Roles of loop C and the loop B-C interval of the nicotinic receptor alpha subunit in its selective interactions with imidacloprid in insects
Spitzmaul_2004_Mol.Membr.Biol_21_39 Mechanistic contributions of residues in the M1 transmembrane domain of the nicotinic receptor to channel gating
Wang_2004_J.Biol.Chem_279_8779 Regulation of the neuronal nicotinic acetylcholine receptor by SRC family tyrosine kinases
Wang_2004_Neurosci_126_305 Presenilin 1 familial Alzheimer's disease mutation leads to defective associative learning and impaired adult neurogenesis
Wu_2004_J.Pharmacol.Exp.Ther_311_80 Electrophysiological, pharmacological, and molecular evidence for alpha7-nicotinic acetylcholine receptors in rat midbrain dopamine neurons
Wu_2004_J.Biol.Chem_279_37842 beta-Amyloid directly inhibits human alpha4beta2-nicotinic acetylcholine receptors heterologously expressed in human SH-EP1 cells
Di Chiara_2004_Neuropharmacol_47 Suppl 1_227 Dopamine and drug addiction: the nucleus accumbens shell connection
Genn_2004_Psychopharmacology.(Berl)_177_93 Effects of nicotine and a cannabinoid receptor agonist on negative contrast: distinction between anxiety and disappointment?
Miyata_2004_Ann.N.Y.Acad.Sci_1025_481 Clinical features of nicotine dependence compared with those of alcohol, methamphetamine, and inhalant dependence
Miyata_2004_Nihon.Shinkei.Seishin.Yakurigaku.Zasshi_24_61 [Studies on clinical characteristics of nicotine dependence using a two compartment model of drug dependence]
Steinman_2004_Nat.Immunol_5_575 Elaborate interactions between the immune and nervous systems
Hanson_2004_Neuron_43_687 Normal patterns of spontaneous activity are required for correct motor axon guidance and the expression of specific guidance molecules
Knight_2004_Neuropharmacol_46_1049 The effect of pregnancy and the oestrus cycle on purinergic and cholinergic responses of the rat urinary bladder
Polo-Parada_2004_J.Neurosci_24_1852 Distinct roles of different neural cell adhesion molecule (NCAM) isoforms in synaptic maturation revealed by analysis of NCAM 180 kDa isoform-deficient mice
Ryten_2004_FASEB.J_18_1404 Purinoceptor expression in regenerating skeletal muscle in the mdx mouse model of muscular dystrophy and in satellite cell cultures
Brady_2004_Methods.Mol.Biol_259_371 Study of G-protein-coupled receptor-protein interactions using gel overlay assays and glutathione-S-transferase-fusion protein pull-downs
Budd_2004_Biochem.J_381_43 Signalling of the M3-muscarinic receptor to the anti-apoptotic pathway
Maurice_2004_J.Neurosci_24_10289 D2 dopamine receptor-mediated modulation of voltage-dependent Na+ channels reduces autonomous activity in striatal cholinergic interneurons
Messer_2004_Curr.Pharm.Des_10_2015 Bivalent ligands for G protein-coupled receptors
Solyakov_2004_J.Biol.Chem_279_43403 Regulation of casein kinase-2 (CK2) activity by inositol phosphates
Tan_2004_Annu.Rev.Pharmacol.Toxicol_44_559 Membrane trafficking of G protein-coupled receptors
Tobin_2004_Methods.Mol.Biol_259_275 G-protein-coupled receptor phosphorylation and palmitoylation
Vial_2004_Biochem.J_382_101 G-protein-coupled receptor regulation of P2X1 receptors does not involve direct channel phosphorylation
Williams_2004_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_137_349 Muscarinic acetylcholine receptors in the brain of the zebrafish (Danio rerio) measured by radioligand binding techniques
Barnes_2004_Proc.Am.Thorac.Soc_1_345 Distribution of receptor targets in the lung
Barnes_2004_Am.J.Med_117 Suppl 12A_24S The role of anticholinergics in chronic obstructive pulmonary disease
Bucchioni_2004_Respir.Med_98_651 Adenosine 5'-monophosphate increases levels of leukotrienes in breath condensate in asthma
Garnier_2004_Circulation_110_1819 Cardiac specific increase in aldosterone production induces coronary dysfunction in aldosterone synthase-transgenic mice
Olianas_2004_Eur.J.Pharmacol_487_65 Action of the muscarinic toxin MT7 on agonist-bound muscarinic M1 receptors
Parsons_2004_J.Physiol_554_687 Localised calcium release events in cells from the muscle of guinea-pig gastric fundus
Potter_2004_Prog.Brain.Res_145_121 Studies of muscarinic neurotransmission with antimuscarinic toxins
Shannon_2004_Epilepsy.Behav_5_857 Effects of antiepileptic drugs on working memory as assessed by spatial alternation performance in rats
Shannon_2004_Eur.J.Pharmacol_498_125 Within-session repeated acquisition behavior in rats as a potential model of executive function
Shannon_2004_Epilepsy.Res_61_49 Seizure susceptibility of neuropeptide-Y null mutant mice in amygdala kindling and chemical-induced seizure models
Tsvilovskyy_2004_Br.J.Pharmacol_143_968 Effects of polyamines on the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle myocytes
vom_2004_Cell.Signal_16_921 Inhibition of phospholipase C-epsilon by Gi-coupled receptors
Zholos_2004_Br.J.Pharmacol_141_23 Phospholipase C, but not InsP3 or DAG, -dependent activation of the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cells
Zholos_2004_J.Gen.Physiol_123_581 G-protein-gated TRP-like cationic channel activated by muscarinic receptors: effect of potential on single-channel gating
Abelson_2004_Basic.Clin.Pharmacol.Toxicol_94_153 The effects of the alpha2-adrenergic receptor agonists clonidine and rilmenidine, and antagonists yohimbine and efaroxan, on the spinal cholinergic receptor system in the rat
Abelson_2004_Neurosci.Lett_368_116 Spinal cholinergic involvement after treatment with aspirin and paracetamol in rats
Akerman_2004_Cell.Calcium_36_397 Ca2+-dependent potentiation of muscarinic receptor-mediated Ca2+ elevation
Avlani_2004_J.Pharmacol.Exp.Ther_308_1062 Application of a kinetic model to the apparently complex behavior of negative and positive allosteric modulators of muscarinic acetylcholine receptors
Bernardini_2004_J.Neurochem_88_1533 Detection of basal and potassium-evoked acetylcholine release from embryonic DRG explants
Christopoulos_2004_Biochem.Soc.Trans_32_873 G-protein-coupled receptor allosterism: the promise and the problem(s)
Coleman_2004_Neurosci_126_831 Acetylcholine release in the pontine reticular formation of C57BL\/6J mouse is modulated by non-M1 muscarinic receptors
Coulson_2004_J.Pharmacol.Exp.Ther_308_760 Insulin regulates neuronal M2 muscarinic receptor function in the ileum of diabetic rats
Demarco_2004_Neurosci_123_17 Carbachol in the pontine reticular formation of C57BL\/6J mouse decreases acetylcholine release in prefrontal cortex
Douglas_2004_Respir.Physiol.Neurobiol_143_251 Pontine and basal forebrain cholinergic interaction: implications for sleep and breathing
Heacock_2004_J.Pharmacol.Exp.Ther_311_1097 Potentiation of the osmosensitive release of taurine and D-aspartate from SH-SY5Y neuroblastoma cells after activation of M3 muscarinic cholinergic receptors
Honma_2004_Ind.Health_42_336 Brain microdialysis study of the effects of hazardous chemicals on the central nervous system 2. Toluene exposure and cerebral acetylcholine
Jacoby_2004_Pulm.Pharmacol.Ther_17_333 Pathophysiology of airway viral infections
Jacoby_2004_J.Aerosol.Med_17_169 Virus-induced asthma attacks
Kommalage_2004_Basic.Clin.Pharmacol.Toxicol_94_238 (+\/-) Epibatidine increases acetylcholine release partly through an action on muscarinic receptors
Krjukova_2004_Br.J.Pharmacol_143_3 Phospholipase C activator m-3M3FBS affects Ca2+ homeostasis independently of phospholipase C activation
Kukkonen_2004_J.Biol.Chem_279_50923 Muscarinic toxin 7 selectivity is dictated by extracellular receptor loops
Lanzafame_2004_J.Pharmacol.Exp.Ther_308_830 Investigation of the interaction of a putative allosteric modulator, N-(2,3-diphenyl-1,2,4-thiadiazole-5-(2H)-ylidene) methanamine hydrobromide (SCH-202676), with M1 muscarinic acetylcholine receptors
Lanzafame_2004_Biochem.Pharmacol_68_2207 Effects of anandamide on the binding and signaling properties of M1 muscarinic acetylcholine receptors
Laplante_2004_Regul.Pept_122_91 Selective reduction in ventral hippocampal acetylcholine release in awake galanin-treated rats and galanin-overexpressing transgenic mice
Laplante_2004_Neuropsychopharmacology_29_1620 Reduction in acetylcholine release in the hippocampus of dopamine D5 receptor-deficient mice
Laplante_2004_J.Neurochem_89_314 Alterations in dopaminergic modulation of prefrontal cortical acetylcholine release in post-pubertal rats with neonatal ventral hippocampal lesions
Laplante_2004_J.Neurochem_91_1473 Effects of neonatal ventral hippocampal lesion in rats on stress-induced acetylcholine release in the prefrontal cortex
Larsen_2004_Acta.Physiol.Scand_182_63 Functional characterization of muscarinic receptor subtypes in human duodenal secretion
Lee_2004_Am.J.Physiol.Lung.Cell.Mol.Physiol_286_L1255 Role of macrophages in virus-induced airway hyperresponsiveness and neuronal M2 muscarinic receptor dysfunction
Mamoon_2004_J.Biomed.Sci_11_810 Regulation of acetylcholine-induced phosphorylation of PLD1 in porcine tracheal smooth muscle
Myslivecek_2004_Ann.N.Y.Acad.Sci_1018_315 The effects of short-term immobilization stress on muscarinic receptors, beta-adrenoceptors, and adenylyl cyclase in different heart regions
Pontari_2004_Am.J.Physiol.Regul.Integr.Comp.Physiol_286_R874 The M2 muscarinic receptor mediates in vitro bladder contractions from patients with neurogenic bladder dysfunction
Sternini_2004_Neurosci_125_103 Role of galanin receptor 1 in peristaltic activity in the guinea pig ileum
Tayebati_2004_Exp.Gerontol_39_217 Age-related changes of muscarinic cholinergic receptor subtypes in the striatum of Fisher 344 rats
Tayebati_2004_Clin.Exp.Hypertens_26_363 Effect of treatment with the cholinesterase inhibitor rivastigmine on vesicular acetylcholine transporter and choline acetyltransferase in rat brain
Uustare_2004_Neurochem.Int_44_119 Characterization of M2 muscarinic receptor activation of different G protein subtypes
Vazquez_2004_J.Neurophysiol_92_2198 GABAA receptors inhibit acetylcholine release in cat pontine reticular formation: implications for REM sleep regulation
Vishnivetskiy_2004_J.Biol.Chem_279_1262 Mapping the arrestin-receptor interface. Structural elements responsible for receptor specificity of arrestin proteins
Walsh_2004_Am.J.Respir.Cell.Mol.Biol_30_333 Effect of eosinophil adhesion on intracellular signaling in cholinergic nerve cells
Weiner_2004_Psychopharmacology.(Berl)_177_207 The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine
Galligan_2004_Neurogastroenterol.Motil_16 Suppl 1_64 Pharmacology and function of nicotinic acetylcholine and P2X receptors in the enteric nervous system
Kim_2004_Bioorg.Med.Chem_12_2357 C(8)-substituted 1-azabicyclo[3.3.1]non-3-enes: a novel scaffold for muscarinic receptor ligands
Lalo_2004_Br.J.Pharmacol_142_1227 Methyllycaconitine, alpha-bungarotoxin and (+)-tubocurarine block fast ATP-gated currents in rat dorsal root ganglion cells
Belyaev_2004_J.Biol.Chem_279_556 Distinct RE-1 silencing transcription factor-containing complexes interact with different target genes
Cauli_2004_J.Neurosci_24_8940 Cortical GABA interneurons in neurovascular coupling: relays for subcortical vasoactive pathways
Gomez_2004_Am.J.Physiol.Heart.Circ.Physiol_286_H2065 Autonomic regulation of calcium and potassium channels is oppositely modulated by microtubules in cardiac myocytes
Hamel_2004_Prog.Brain.Res_145_171 Cholinergic modulation of the cortical microvascular bed
Itzhaki_2004_FEBS.Lett_564_157 G protein-activated K+ channels: a reporter for rapid activation of G proteins by lysophosphatidic acid in Xenopus oocytes
Jiang_2004_Zhongguo.Ying.Yong.Sheng.Li.Xue.Za.Zhi_20_243 [Preliminary studies of the mechanism of carbachol increase contraction in rat ventricular myocytes]
Knol_2004_Nucl.Med.Biol_31_111 Synthesis and evaluation of iodinated TZTP-derivatives as potential radioligands for imaging of muscarinic M2 receptors with SPET
Ma_2004_Biotechnol.Lett_26_1441 Mathematical basis for the optimization of single cell-line screening on multi-well plates
Nemmani_2004_Pain_109_274 Modulation of morphine analgesia by site-specific N-methyl-D-aspartate receptor antagonists: dependence on sex, site of antagonism, morphine dose, and time
Park_2004_FEBS.Lett_567_344 Characterization of radioligand binding to a transmembrane receptor reconstituted into Lipobeads
Park_2004_J.Neurochem_90_537 Oligomeric potential of the M2 muscarinic cholinergic receptor
Sener_2004_J.Pharm.Pharmacol_56_359 Melatonin reverses urinary system and aorta damage in the rat due to chronic nicotine administration
Hellstrom-Lindahl_2004_Eur.J.Neurosci_19_2703 Nicotine reduces A beta in the brain and cerebral vessels of APPsw mice
Bernstein_2004_J.Biol.Chem_279_21248 RGS2 binds directly and selectively to the M1 muscarinic acetylcholine receptor third intracellular loop to modulate Gq\/11alpha signaling
Jensen_2004_Eur.J.Pharmacol_497_125 Carbamoylcholine homologs: synthesis and pharmacology at nicotinic acetylcholine receptors
Mao_2004_J.Biol.Chem_279_26314 RGS17\/RGSZ2, a novel regulator of Gi\/o, Gz, and Gq signaling
Clader_2004_Bioorg.Med.Chem_12_319 Muscarinic M2 antagonists: anthranilamide derivatives with exceptional selectivity and in vivo activity
Gamper_2004_J.Neurosci_24_10980 Phosphatidylinositol [correction] 4,5-bisphosphate signals underlie receptor-specific Gq\/11-mediated modulation of N-type Ca2+ channels
Ishiwari_2004_J.Neurosci.Methods_140_39 The GABA uptake inhibitor beta-alanine reduces pilocarpine-induced tremor and increases extracellular GABA in substantia nigra pars reticulata as measured by microdialysis
Palani_2004_Bioorg.Med.Chem.Lett_14_1791 Isopropyl amide derivatives of potent and selective muscarinic M2 receptor antagonists
Shapiro_2004_J.Gen.Physiol_123_657 Why biophysicists make models: quantifying modulation of the M current
Griffin_2004_J.Pharmacol.Exp.Ther_308_339 Muscarinic agonist-mediated heterologous desensitization in isolated ileum requires activation of both muscarinic M2 and M3 receptors
Seeger_2004_J.Neurosci_24_10117 M2 muscarinic acetylcholine receptor knock-out mice show deficits in behavioral flexibility, working memory, and hippocampal plasticity
Wang_2004_Neuropsychopharmacology_29_2126 Decreased amphetamine-induced locomotion and improved latent inhibition in mice mutant for the M5 muscarinic receptor gene found in the human 15q schizophrenia region
Adams_2004_Brain.Res.Mol.Brain.Res_129_67 In vitro and in vivo effects of an alpha3 neuronal nicotinic acetylcholine receptor antisense oligonucleotide
Brioni_2004_Proc.Natl.Acad.Sci.U.S.A_101_6758 Activation of dopamine D4 receptors by ABT-724 induces penile erection in rats
Cowart_2004_J.Med.Chem_47_3853 Discovery of 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole (ABT-724), a dopaminergic agent with a novel mode of action for the potential treatment of erectile dysfunction
Donnelly-Roberts_2004_J.Pharmacol.Exp.Ther_308_1053 Mitogen-activated protein kinase and caspase signaling pathways are required for P2X7 receptor (P2X7R)-induced pore formation in human THP-1 cells
Hsieh_2004_J.Pharmacol.Exp.Ther_308_330 Central mechanisms regulating penile erection in conscious rats: the dopaminergic systems related to the proerectile effect of apomorphine
Matulenko_2004_Bioorg.Med.Chem_12_3471 Synthesis and functional activity of (2-aryl-1-piperazinyl)-N-(3-methylphenyl)acetamides: selective dopamine D4 receptor agonists
Matulenko_2004_Bioorg.Med.Chem.Lett_14_5095 Synthesis and activity of 2-[4-(4-[3H]-2-cyanophenyl)piperazinyl]-N-(2,4,6-[3H]3-3-methylphenyl)acetamide: a selective dopamine D4 receptor agonist and radioligand
Moreland_2004_Biochem.Pharmacol_68_761 Comparative pharmacology of human dopamine D(2)-like receptor stable cell lines coupled to calcium flux through Galpha(qo5)
Rueter_2004_CNS.Drug.Rev_10_167 ABT-089: pharmacological properties of a neuronal nicotinic acetylcholine receptor agonist for the potential treatment of cognitive disorders
Stewart_2004_J.Med.Chem_47_2348 Dopamine D4 ligands and models of receptor activation: 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole and related heteroarylmethylarylpiperazines exhibit a substituent effect responsible for additional efficacy tuning
Brody_2004_Am.J.Psychiatry_161_1211 Smoking-induced ventral striatum dopamine release
Bruijnzeel_2004_Neuropharmacol_47_572 Adaptations in cholinergic transmission in the ventral tegmental area associated with the affective signs of nicotine withdrawal in rats
Crooks_2004_Bioorg.Med.Chem.Lett_14_1869 Development of subtype-selective ligands as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release
Dwoskin_2004_Bioorg.Med.Chem.Lett_14_1863 Subtype-selective nicotinic receptor antagonists: potential as tobacco use cessation agents
Gatto_2004_CNS.Drug.Rev_10_147 TC-1734: an orally active neuronal nicotinic acetylcholine receptor modulator with antidepressant, neuroprotective and long-lasting cognitive effects
McKirdy_2004_Br.J.Surg_91_229 Differential effect of nitric oxide synthase inhibition on sigmoid colon longitudinal and circular muscle responses to nicotine and nerve stimulation in vitro
Middleton_2004_J.Pharmacol.Exp.Ther_308_367 Nicotinic receptor modulation of dopamine transporter function in rat striatum and medial prefrontal cortex
Miller_2004_J.Pharmacol.Exp.Ther_310_1035 Lobeline analogs with enhanced affinity and selectivity for plasmalemma and vesicular monoamine transporters
Neugebauer_2004_Brain.Res.Dev.Brain.Res_153_213 Effects of environmental enrichment on behavior and dopamine transporter function in medial prefrontal cortex in adult rats prenatally treated with cocaine
Newhouse_2004_Curr.Opin.Pharmacol_4_36 Effects of nicotinic stimulation on cognitive performance
O'Dell_2004_Ann.N.Y.Acad.Sci_1021_167 Nicotine withdrawal in adolescent and adult rats
O'Neill_2004_J.Appl.Physiol.(1985)_97_1938 Effects of reduced free fatty acid availability on hormone-sensitive lipase activity in human skeletal muscle during aerobic exercise
O'Neill_2004_Expert.Opin.Investig.Drugs_13_1369 SMi 4th Annual Conference on Neurodegenerative Disorders: a focus on Alzheimer's and Parkinson's disease
Paterson_2004_Psychopharmacology.(Berl)_173_64 Prolonged nicotine dependence associated with extended access to nicotine self-administration in rats
Rahman_2004_Neurochem.Res_29_1687 Local perfusion of nicotine differentially modulates somatodendritic dopamine release in the rat ventral tegmental area after nicotine preexposure
Rahman_2004_Neurosci_129_415 Neuroadaptive changes in the mesoaccumbens dopamine system after chronic nicotine self-administration: a microdialysis study
Spielewoy_2004_Behav.Genet_34_343 Strain-specificity in nicotine attenuation of phencyclidine-induced disruption of prepulse inhibition in mice: relevance to smoking in schizophrenia patients
Terry_2004_J.Neurogenet_18_429 VEGF promoter haplotype and amyotrophic lateral sclerosis (ALS)
Peters_2004_Biochem.Soc.Trans_32_547 The 5-hydroxytryptamine type 3 (5-HT3) receptor reveals a novel determinant of single-channel conductance
Wang_2004_Nat.Med_10_1216 Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis
Harris_2004_Neuropsychopharmacology_29_1378 Effects of nicotine on cognitive deficits in schizophrenia
Brown_2004_Eur.J.Neurosci_19_1634 Adulthood nicotine treatment alleviates behavioural impairments in rats neonatally treated with quinpirole: possible roles of acetylcholine function and neurotrophic factor expression
Kong_2004_EMBO.Rep_5_183 Inhibition of synapse assembly in mammalian muscle in vivo by RNA interference
Alarcon_2004_Learn.Mem_11_318 Selective modulation of some forms of schaffer collateral-CA1 synaptic plasticity in mice with a disruption of the CPEB-1 gene
Bailey_2004_Neuron_44_49 The persistence of long-term memory: a molecular approach to self-sustaining changes in learning-induced synaptic growth
Han_2004_Learn.Mem_11_421 Role of Aplysia cell adhesion molecules during 5-HT-induced long-term functional and structural changes
Huang_2004_Proc.Natl.Acad.Sci.U.S.A_101_859 A form of long-lasting, learning-related synaptic plasticity in the hippocampus induced by heterosynaptic low-frequency pairing
Huang_2004_Proc.Natl.Acad.Sci.U.S.A_101_3236 Genetic evidence for the bidirectional modulation of synaptic plasticity in the prefrontal cortex by D1 receptors
Huxley_2004_Eur.J.Biochem_271_1403 Fifty years of muscle and the sliding filament hypothesis
Huxley_2004_J.Muscle.Res.Cell.Motil_25_443 Jean Hanson's legacy
Huxley_2004_Philos.Trans.R.Soc.Lond.B.Biol.Sci_359_1879 Recent X-ray diffraction studies of muscle contraction and their implications
Kandel_2004_Biosci.Rep_24_475 The molecular biology of memory storage: a dialog between genes and synapses
Lang_2004_Proc.Natl.Acad.Sci.U.S.A_101_16665 Transient expansion of synaptically connected dendritic spines upon induction of hippocampal long-term potentiation
Nolan_2004_Cell_119_719 A behavioral role for dendritic integration: HCN1 channels constrain spatial memory and plasticity at inputs to distal dendrites of CA1 pyramidal neurons
Ibanez-Tallon_2004_Hum.Mol.Genet_13_2133 Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation
Ibanez-Tallon_2004_Neuron_43_305 Tethering naturally occurring peptide toxins for cell-autonomous modulation of ion channels and receptors in vivo
Kalodimos_2004_Science_305_386 Structure and flexibility adaptation in nonspecific and specific protein-DNA complexes
Leslie_2004_Ann.N.Y.Acad.Sci_1021_148 Adolescent development of forebrain stimulant responsiveness: insights from animal studies
Liu_2004_Mol.Biochem.Parasitol_134_267 Genomic organization of an avermectin receptor subunit from Haemonchus contortus and expression of its putative promoter region in Caenorhabditis elegans
Gally_2004_Nature_431_578 A transmembrane protein required for acetylcholine receptor clustering in Caenorhabditis elegans
Rostaing_2004_J.Histochem.Cytochem_52_1 Preservation of immunoreactivity and fine structure of adult C. elegans tissues using high-pressure freezing
Bornscheuer_2004_Nat.Biotechnol_22_1098 Finding enzymatic gold on silver surfaces
Schmidt_2004_Methods.Enzymol_388_199 Directed evolution of lipases and esterases
Espanol_2004_Int.J.Mol.Med_13_311 Different muscarinc receptors are involved in the proliferation of murine mammary adenocarcinoma cell lines
Morar_2004_Am.J.Hum.Genet_75_596 Mutation history of the roma\/gypsies
Grimwood_2004_Nature_428_529 The DNA sequence and biology of human chromosome 19
Vastag_2004_Antonie.Van.Leeuwenhoek_86_111 Cloning and sequence analysis of the glyceraldehyde-3-phosphate dehydrogenase gene from the zygomycetes fungus Rhizomucor miehei
Caboni_2004_Chem.Res.Toxicol_17_1540 Rotenone, deguelin, their metabolites, and the rat model of Parkinson's disease
Zhang_2004_J.Org.Chem_69_876 Alpha-nitro ketone as an electrophile and nucleophile: synthesis of 3-substituted 2-nitromethylenetetrahydrothiophene and -tetrahydrofuran as drosophila nicotinic receptor probes
Zhang_2004_Neurosci.Lett_371_56 Drosophila nicotinic receptors: evidence for imidacloprid insecticide and alpha-bungarotoxin binding to distinct sites
Tremolada_2004_Ecotoxicology_13_589 Coumaphos distribution in the hive ecosystem: case study for modeling applications
Bergers_2004_Inhal.Toxicol_16_141 Respiration-based measurement of lung deposition of a fluorescent dextrane aerosol in a marmoset monkey
Joosen_2004_Arch.Toxicol_78_34 Cardiovascular effects of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) decisive for its therapeutic efficacy in sarin poisoning
van Helden_2004_Inhal.Toxicol_16_549 Protection of rats against perfluoroisobutene (PFIB)-induced pulmonary edema by curosurf and N-acetylcysteine
Chudasama_2004_Learn.Mem_11_78 Cholinergic modulation of visual attention and working memory: dissociable effects of basal forebrain 192-IgG-saporin lesions and intraprefrontal infusions of scopolamine
Chudasama_2004_Psychopharmacology.(Berl)_174_86 Psychopharmacological approaches to modulating attention in the five-choice serial reaction time task: implications for schizophrenia
Dalley_2004_Cereb.Cortex_14_922 Cortical cholinergic function and deficits in visual attentional performance in rats following 192 IgG-saporin-induced lesions of the medial prefrontal cortex
Lysek_2004_Biochemistry_43_10393 Prion protein interaction with the C-terminal SH3 domain of Grb2 studied using NMR and optical spectroscopy
Winters_2004_Eur.J.Neurosci_19_490 Selective cholinergic denervation of the cingulate cortex impairs the acquisition and performance of a conditional visual discrimination in rats
Berrettini_2004_Psychiatry.(Edgmont)_1_12 Nicotine dependence
Lerman_2004_Pharmacogenomics.J_4_184 The functional mu opioid receptor (OPRM1) Asn40Asp variant predicts short-term response to nicotine replacement therapy in a clinical trial
Rhodes_2004_J.Neurosci_24_7903 KChIPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brain
Dobransky_2004_J.Biol.Chem_279_52059 Protein kinase C isoforms differentially phosphorylate human choline acetyltransferase regulating its catalytic activity
Torrent_2004_Biochemistry_43_7162 High pressure induces scrapie-like prion protein misfolding and amyloid fibril formation
Metherate_2004_Learn.Mem_11_50 Nicotinic acetylcholine receptors in sensory cortex
Metherate_2004_Prog.Brain.Res_145_143 Synaptic mechanisms and cholinergic regulation in auditory cortex
Gard_2004_Expert.Rev.Neurother_4_87 Angiotensin and Alzheimer's disease: therapeutic prospects
Morley_2004_Brain.Res_1023_41 A phenotype for the alpha 7 nicotinic acetylcholine receptor null mutant
Bahar_2004_Eur.J.Neurosci_19_1115 Amygdalar circuits required for either consolidation or extinction of taste aversion memory are not required for reconsolidation
Bahar_2004_J.Neurophysiol_92_3298 Neural signature of taste familiarity in the gustatory cortex of the freely behaving rat
Berman_2004_Methods.Mol.Biol_250_315 MAPK cascades in the brain: lessons from learning
Dudai_2004_Annu.Rev.Psychol_55_51 The neurobiology of consolidations, or, how stable is the engram?
Dudai_2004_Neuron_44_93 Rites of passage of the engram: reconsolidation and the lingering consolidation hypothesis
Eisenberg_2004_Eur.J.Neurosci_20_3397 Reconsolidation of fresh, remote, and extinguished fear memory in Medaka: old fears don't die
Guitton_2004_Biol.Psychiatry_56_901 Anxiety-like state associates with taste to produce conditioned taste aversion
Aarsland_2004_J.Geriatr.Psychiatry.Neurol_17_164 Role of cholinesterase inhibitors in Parkinson's disease and dementia with Lewy bodies
Akiyama_2004_Neurochem.Int_44_497 Simultaneous monitoring of acetylcholine and catecholamine release in the in vivo rat adrenal medulla
Allgaier_2004_Med.Monatsschr.Pharm_27_223 [Galantamine, an acetylcholinesterase inhibitor with various actions]
Amali_2004_Dev.Dyn_229_847 Up-regulation of muscle-specific transcription factors during embryonic somitogenesis of zebrafish (Danio rerio) by knock-down of myostatin-1
Anstead_2004_Insect.Biochem.Mol.Biol_34_871 High-throughput detection of knockdown resistance in Myzus persicae using allelic discriminating quantitative PCR
Arai_2004_Nihon.Ronen.Igakkai.Zasshi_41_310 [Current therapies in dementia]
Ardhaoui_2004_J.Biotechnol_110_265 Effect of acyl donor chain length and substitutions pattern on the enzymatic acylation of flavonoids
Arreola_2004_Transplantation_78_296 Possible role of substance P in the ischemia-reperfusion injury in the isolated rabbit lung
Arruda_2004_Neurosci.Res_49_289 Ionotropic glutamate receptors regulating labeled acetylcholine release from rat striatal tissue in vitro: possible involvement of receptor modulation in magnesium sensitivity
Arsov_2004_Eur.Biophys.J_33_715 The membrane lateral domain approach in the studies of lipid-protein interaction of GPI-anchored bovine erythrocyte acetylcholinesterase
Ashwell_2004_Brain.Behav.Evol_64_223 The claustrum is not missing from all monotreme brains
Asidi_2004_Med.Vet.Entomol_18_134 Experimental hut comparisons of nets treated with carbamate or pyrethroid insecticides, washed or unwashed, against pyrethroid-resistant mosquitoes
Atta-Ur-Rahman_2004_Chem.Pharm.Bull.(Tokyo)_52_802 New cholinesterase inhibiting bisbenzylisoquinoline alkaloids from Cocculus pendulus
Badellino_2004_Curr.Opin.Cardiol_19_392 The role of endothelial lipase in high-density lipoprotein metabolism
Bajgar_2004_Cent.Eur.J.Public.Health_12 Suppl_S4 Biochemical effects of low level exposure to soman vapour
Bajgar_2004_Inhal.Toxicol_16_497 Biochemical and behavioral effects of soman vapors in low concentrations
Balzarini_2004_Int.J.Biochem.Cell.Biol_36_1848 Obligatory involvement of CD26\/dipeptidyl peptidase IV in the activation of the antiretroviral tripeptide glycylprolylglycinamide (GPG-NH(2))
Banaschewski_2004_Eur.Child.Adolesc.Psychiatry_13 Suppl 1_I102 Non-stimulant medications in the treatment of ADHD
Bar-Am_2004_J.Neurochem_89_1119 Regulation of protein kinase C by the anti-Parkinson drug, MAO-B inhibitor, rasagiline and its derivatives, in vivo
Barth_2004_Bioinformatics_20_2845 The database of epoxide hydrolases and haloalkane dehalogenases: one structure, many functions
Barth_2004_Proteins_55_846 Sequence and structure of epoxide hydrolases: a systematic analysis
Bastos_2004_Bull.Environ.Contam.Toxicol_72_798 Paraoxonase activity in sera of four neotropical fish
Battershill_2004_Food.Chem.Toxicol_42_1279 Toxicological assessment of isomeric pesticides: a strategy for testing of chiral organophosphorus (OP) compounds for delayed polyneuropathy in a regulatory setting
Benhamou_2004_Anesthesiology_101_271 Are local anesthetics needed for local anesthesia?
Bicker_2004_Cell.Tissue.Res_317_207 Cellular expression patterns of acetylcholinesterase activity during grasshopper development
Blanton_2004_J.Biochem.Mol.Toxicol_18_115 Global changes in the expression patterns of RNA isolated from the hippocampus and cortex of VX exposed mice
Blesa_2004_Alzheimer.Dis.Assoc.Disord_18 Suppl 1_S9 Noncognitive symptoms and long-term treatment expectations for Alzheimer disease
Bliwise_2004_Clin.Cornerstone_6 Suppl 1A_S16 Sleep disorders in Alzheimer's disease and other dementias
Boise_2004_J.Gerontol.A.Biol.Sci.Med.Sci_59_M621 Dementia assessment in primary care: results from a study in three managed care systems
Boldrini_2004_Pathol.Res.Pract_200_231 Wolman disease and cholesteryl ester storage disease diagnosed by histological and ultrastructural examination of intestinal and liver biopsy
Bonacci_2004_Mar.Pollut.Bull_49_445 Esterase activities in the bivalve mollusc Adamussium colbecki as a biomarker for pollution monitoring in the Antarctic marine environment
Bondarenko_2004_Environ.Toxicol.Chem_23_1809 Degradation and sorption of selected organophosphate and carbamate insecticides in urban stream sediments
Boopathy_2004_Protein.J_23_325 Aryl acylamidase activity on acetylcholinesterase is high during early chicken brain development
Borroni_2004_Alzheimer.Dis.Assoc.Disord_18_32 Predicting cognitive decline in Alzheimer disease. Role of platelet amyloid precursor protein
Bosboom_2004_Expert.Opin.Drug.Saf_3_209 Psychotic symptoms in Parkinson's disease: pathophysiology and management
Bouger_2004_Eur.Neuropsychopharmacol_14_285 Effects of acute and repeated administration of a cholinesterase inhibitor on timing behaviour
Boutsiouki_2004_J.Appl.Physiol.(1985)_97_1091 Modulation of microvascular function following low-dose exposure to the organophosphorous compound malathion in human skin in vivo
Braga_2004_Mem.Inst.Oswaldo.Cruz_99_199 Aedes aegypti resistance to temephos during 2001 in several municipalities in the states of Rio de Janeiro, Sergipe, and Alagoas, Brazil
Brahmi_2004_Vet.Hum.Toxicol_46_187 Extrapyramidal syndrome as a delayed and reversible complication of acute dichlorvos organophosphate poisoning
Branda_2004_J.Bacteriol_186_3970 Genes involved in formation of structured multicellular communities by Bacillus subtilis
Brimer_2004_Exp.Appl.Acarol_33_81 Rapid quantitative assay for acaricidal effects on Sarcoptes scabiei var. suis and Otodectes cynotis
Brown_2004_Environ.Toxicol.Chem_23_1680 Contaminant effects on the teleost fish thyroid
Buccafusco_2004_J.Mol.Neurosci_24_85 Donepezil-induced improvement in delayed matching accuracy by young and old rhesus monkeys
Bucur_2004_Biosens.Bioelectron_20_217 Versatile method of cholinesterase immobilisation via affinity bonds using Concanavalin A applied to the construction of a screen-printed biosensor
Bui_2004_J.Am.Chem.Soc_126_7198 Acetylcholinesterase: enhanced fluctuations and alternative routes to the active site in the complex with fasciculin-2
Bullock_2004_Alzheimer.Dis.Assoc.Disord_18 Suppl 1_S17 The needs of the caregiver in the long-term treatment of Alzheimer disease
Burillo-Putze_2004_Am.J.Emerg.Med_22_327 Late administration of pralidoxime in organophosphate (fenitrothion) poisoning
Cantegreil-Kallen_2004_Rev.Med.Interne_25_548 [Detection of Alzheimer's disease in general medicine: preliminary results of a Sentinelles general practitioner's network survey]
Capacio_2004_Drug.Chem.Toxicol_27_95 Pharmacokinetic studies of intramuscular midazolam in guinea pigs challenged with soman
Carlson_2004_J.Toxicol.Environ.Health.A_67_905 Influence of selected inhibitors on the metabolism of the styrene metabolite 4-vinylphenol in wild-type and CYP2E1 knockout mice
Caro_2004_Drugs.Aging_21_677 Assessing the health and economic impact of galantamine treatment in patients with Alzheimer's disease in the health care systems of different countries
Cartaud_2004_J.Cell.Biol_165_505 MuSK is required for anchoring acetylcholinesterase at the neuromuscular junction
Cavalli_2004_J.Med.Chem_47_3991 A computational study of the binding of propidium to the peripheral anionic site of human acetylcholinesterase
Cejkova_2004_Histol.Histopathol_19_669 Dipeptidyl peptidase IV (DPPIV) activity in the tear fluid as an indicator of the severity of corneal injury: a histochemical and biochemical study
Ceravolo_2004_Clin.Neuropharmacol_27_166 Cerebral perfusional effects of cholinesterase inhibitors in Alzheimer disease
Champtiaux_2004_Prog.Brain.Res_145_235 Knockout and knockin mice to investigate the role of nicotinic receptors in the central nervous system
Chang_2004_Birth.Defects.Res.A.Clin.Mol.Teratol_70_28 Developmental toxicity of arecoline, the major alkaloid in betel nuts, in zebrafish embryos
Cho_2004_Appl.Environ.Microbiol_70_4681 Altering the substrate specificity of organophosphorus hydrolase for enhanced hydrolysis of chlorpyrifos
Cho_2004_J.Toxicol.Environ.Health.A_67_987 Neurofilament 200 as an indicator of differences between mipafox and paraoxon sensitivity in Sy5Y neuroblastoma cells
Clemente_2004_J.Comp.Neurol_474_75 Cholinergic elements in the zebrafish central nervous system: Histochemical and immunohistochemical analysis
Cohen_2004_J.Neurochem_90_1059 NFATc1 activates the acetylcholinesterase promoter in rat muscle
Colgin_2004_J.Neurophysiol_92_3385 Spontaneous waves in the dentate gyrus of slices from the ventral hippocampus
Collombet_2004_Ann.Pharm.Fr_62_247 [Stem-cell engraftment as delayed therapy to repair organophosphate-induced brain damage]
Combi_2004_Brain.Res.Bull_63_353 Evidence for a fourth locus for autosomal dominant nocturnal frontal lobe epilepsy
Corbel_2004_J.Med.Entomol_41_712 Dinotefuran: a potential neonicotinoid insecticide against resistant mosquitoes
Corsi_2004_Mar.Environ.Res_58_401 Cholinesterase activities in the Antarctic scallop Adamussium colbecki: tissue expression and effect of ZnCl2 exposure
Courtney_2004_Lancet_363_2105 Long-term donepezil treatment in 565 patients with Alzheimer's disease (AD2000): randomised double-blind trial
Cummings_2004_N.Engl.J.Med_351_56 Alzheimer's disease
Darvesh_2004_Exp.Neurol_188_461 Cholinesterase inhibitors modify the activity of intrinsic cardiac neurons
Das_2004_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_138_3 Nitrite toxicity in Indian major carps: sublethal effect on selected enzymes in fingerlings of Catla catla, Labeo rohita and Cirrhinus mrigala
Dautzenberg_2004_Int.J.Geriatr.Psychiatry_19_641 Delirium in elderly hospitalised patients: protective effects of chronic rivastigmine usage
Davey_2004_J.Med.Entomol_41_524 Control of an organophosphate-resistant strain of Boophilus microplus (Acari: Ixodidae) infested on cattle after a series of dips in coumaphos applied at different treatment intervals
de Aguiar_2004_Environ.Res_95_224 Metabolical effects of Folidol 600 on the neotropical freshwater fish matrinxa, Brycon cephalus
De Coninck_2004_J.Ind.Microbiol.Biotechnol_31_204 Factorial designs: an efficient approach to choosing the main factors influencing growth and hydrolase production by Tetrahymena thermophila
Degenhardt_2004_J.Anal.Toxicol_28_364 Improvements of the fluoride reactivation method for the verification of nerve agent exposure
Demarchi_2004_Aliment.Pharmacol.Ther_19_1261 Influence of a lipase inhibitor on gastric sensitivity and accommodation to an orally ingested meal
Dichek_2004_Arterioscler.Thromb.Vasc.Biol_24_1696 Divergent effects of the catalytic and bridging functions of hepatic lipase on atherosclerosis
Dominguez_2004_Biotechnol.Lett_26_705 Quantification of intra- and extra-cellular thermophilic lipase\/esterase production by Thermus sp
Doss-Pepe_2004_Biochim.Biophys.Acta_1698_187 Stepwise construction of triple-helical heparin binding sites using peptide models
Ege_2004_Acta.Radiol_45_111 Spontaneous rupture of mediastinal cystic teratoma with high levels of amylase, lipase, CA 19-9, CA 125 and CEA in cystic fluid: a case report
El-Demerdash_2004_Food.Chem.Toxicol_42_1563 Cadmium-induced changes in lipid peroxidation, blood hematology, biochemical parameters and semen quality of male rats: protective role of vitamin E and beta-carotene
el-Demerdash_2004_J.Environ.Sci.Health.B_39_443 Role of alpha-tocopherol and beta-carotene in ameliorating the fenvalerate-induced changes in oxidative stress, hemato-biochemical parameters, and semen quality of male rats
Emre_2004_Curr.Opin.Neurol_17_399 Dementia in Parkinson's disease: cause and treatment
Engberg_2004_Poult.Sci_83_925 Influence of whole wheat and xylanase on broiler performance and microbial composition and activity in the digestive tract
Engedal_2004_Tidsskr.Nor.Laegeforen_124_1641 [Effect of drugs against dementia]
Enz_2004_Neuropharmacol_47_408 Co-administration of memantine has no effect on the in vitro or ex vivo determined acetylcholinesterase inhibition of rivastigmine in the rat brain
Erkinjuntti_2004_Neurol.Res_26_603 Treatment of vascular dementia-evidence from clinical trials with cholinesterase inhibitors
Eskenazi_2004_Environ.Health.Perspect_112_1116 Association of in utero organophosphate pesticide exposure and fetal growth and length of gestation in an agricultural population
Evans_2004_Int.J.Neuropsychopharmacol_7_351 Evidence-based pharmacotherapy of Alzheimer's disease
Falkenstein_2004_J.Pept.Sci_10_342 Synthesis and characterization of a chimeric peptide derived from fasciculin that inhibits acetylcholinesterase
Farooqui_2004_Brain.Res.Brain.Res.Rev_45_179 Retinoic acid-mediated phospholipase A2 signaling in the nucleus
Fayuk_2004_Mol.Pharmacol_66_658 Regulation of nicotinic acetylcholine receptor channel function by acetylcholinesterase inhibitors in rat hippocampal CA1 interneurons
Fernandez-Castro_2004_Clin.Exp.Rheumatol_22_505 Myasthenia gravis: an unusual cause of diplopia in polymyalgia rheumatica
Feulner_2004_Infect.Immun_72_3171 Identification of acyloxyacyl hydrolase, a lipopolysaccharide-detoxifying enzyme, in the murine urinary tract
Fex_2004_Endocrinology_145_3746 Hormone-sensitive lipase deficiency in mouse islets abolishes neutral cholesterol ester hydrolase activity but leaves lipolysis, acylglycerides, fat oxidation, and insulin secretion intact
Figueroa-Espinoza_2004_J.Agric.Food.Chem_52_4240 Enzymatic solubilization of arabinoxylans from native, extruded, and high-shear-treated rye bran by different endo-xylanases and other hydrolyzing enzymes
Fillit_2004_Alzheimer.Dis.Assoc.Disord_18 Suppl 1_S24 The economic benefits of acetylcholinesterase inhibitors for patients with Alzheimer disease and associated dementias
Fleischli_2004_Arch.Environ.Contam.Toxicol_46_542 Avian mortality events in the United States caused by anticholinesterase pesticides: a retrospective summary of National Wildlife Health Center records from 1980 to 2000
Forestier_2004_Prenat.Diagn_24_478 False-positive amniotic fluid acetylcholinesterase PAGE due to contamination by the AFP diluent of an automated instrument
Francotte_2004_Curr.Med.Chem_11_1757 New trends in the design of drugs against Alzheimer's disease
Fuschillo_2004_Arch.Gerontol.Geriatr.Suppl__187 Alzheimer's disease and acetylcholinesterase inhibitor agents: a two-year longitudinal study
Gabelt_2004_Invest.Ophthalmol.Vis.Sci_45_2732 H-7 effect on outflow facility after trabecular obstruction following long-term echothiophate treatment in monkeys
Gardino_2004_J.Chem.Neuroanat_27_267 Identification of neurons with acetylcholinesterase and NADPH-diaphorase activities in the centrifugal visual system of the chick
Garg_2004_Toxicol.Pathol_32_364 Pathophysiological effects of chronic toxicity with synthetic pyrethroid, organophosphate and chlorinated pesticides on bone health of broiler chicks
Giacobini_2004_Pharmacol.Res_50_433 Cholinesterase inhibitors: new roles and therapeutic alternatives
Gilani_2004_Life.Sci_75_2377 Presence of cholinomimetic and acetylcholinesterase inhibitory constituents in betel nut
Gill_2004_N.Engl.J.Med_350_2213 Management of overactive bladder
Gimenez-Pardo_2004_Mem.Inst.Oswaldo.Cruz_99_223 Ivermectin resistant and susceptible third-stage larvae of Haemonchus contortus: cholinesterase and phosphatase activities
Ginalska_2004_J.Ind.Microbiol.Biotechnol_31_177 A thermostable lipase produced by a newly isolated Geotrichum-like strain, R59
Girardi_2004_Am.J.Physiol.Cell.Physiol_287_C1238 Role of dipeptidyl peptidase IV in regulating activity of Na+\/H+ exchanger isoform NHE3 in proximal tubule cells
Giubilei_2004_Dement.Geriatr.Cogn.Disord_18_338 Increased lymphocyte dopamine beta-hydroxylase immunoreactivity in Alzheimer's disease: compensatory response to cholinergic deficit?
Giunta_2004_Brain.Res.Bull_64_165 Galantamine and nicotine have a synergistic effect on inhibition of microglial activation induced by HIV-1 gp120
Gobec_2004_Bioorg.Med.Chem.Lett_14_3559 Phosphonate inhibitors of antigen 85C, a crucial enzyme involved in the biosynthesis of the Mycobacterium tuberculosis cell wall
Gomez_2004_Atherosclerosis_174_73 Influence of the -514C\/T polymorphism in the promoter of the hepatic lipase gene on postprandial lipoprotein metabolism
Gonzalez_2004_Mem.Inst.Oswaldo.Cruz_99_335 Role of enhanced detoxication in a deltamethrin-resistant population of Triatoma infestans (Hemiptera, Reduviidae) from Argentina
Gorelick_2004_Drugs_64_1547 Agents in development for the management of cocaine abuse
Gouedard_2004_Mol.Cell.Biol_24_5209 Dietary polyphenols increase paraoxonase 1 gene expression by an aryl hydrocarbon receptor-dependent mechanism
Grmec_2004_Acad.Emerg.Med_11_925 Glasgow Coma Scale score and QTc interval in the prognosis of organophosphate poisoning
Grossberg_2004_Am.J.Geriatr.Psychiatry_12_420 Rivastigmine in Alzheimer disease: efficacy over two years
Guloglu_2004_Am.J.Emerg.Med_22_328 Dichlorvos poisoning after intramuscular injection
Gundisch_2004_Bioorg.Med.Chem_12_4953 Synthesis and evaluation of phenylcarbamate derivatives as ligands for nicotinic acetylcholine receptors
Gupta_2004_Can.J.Microbiol_50_361 A glycerol-inducible thermostable lipase from Bacillus sp.: medium optimization by a Plackett-Burman design and by response surface methodology
Guven_2004_Hum.Exp.Toxicol_23_365 The effect of plasmapheresis on plasma cholinesterase levels in a patient with organophosphate poisoning
Hallam_2004_Behav.Brain.Res_153_481 An investigation of the effect of tacrine and physostigmine on spatial working memory deficits in the olfactory bulbectomised rat
Handrick_2004_FEMS.Microbiol.Lett_230_265 The activator of the Rhodospirillum rubrum PHB depolymerase is a polypeptide that is extremely resistant to high temperature (121 degrees C) and other physical or chemical stresses
Harper_2004_Semin.Neurol_24_111 Congenital myasthenic syndromes
Hasan_2004_J.Appl.Toxicol_24_257 In vivo metoclopramide protection of cholinesterase from paraoxon inhibition: direct comparison with pralidoxime in subchronic low-dose exposure
Hassan_2004_Int.Immunopharmacol_4_1223 Evaluation of immunotoxicity induced by propoxure in C57Bl\/6 mice
Hassiotis_2004_J.Comp.Neurol_475_493 Cyto- and chemoarchitecture of the cerebral cortex of the Australian echidna (Tachyglossus aculeatus). I. Areal organization
Hazen_2004_Adv.Exp.Med.Biol_542_309 Evaluation of water washes for the removal of organophosphorus pesticides from Maine wild blueberries
Hediger_2004_Dev.Genes.Evol_214_29 Sex determination in Drosophila melanogaster and Musca domestica converges at the level of the terminal regulator doublesex
Hernandez_2004_J.Toxicol.Environ.Health.A_67_1095 Effect of long-term exposure to pesticides on plasma esterases from plastic greenhouse workers
Hirouchi_2004_Nihon.Yakurigaku.Zasshi_123_421 [Current status and perspectives on the development of therapeutic agents for Alzheimer's disease]
Horvath_2004_J.Neurobiol_60_463 Neonatal handling increases sensitivity to acute neurodegeneration in adult rats
Hsiao_2004_J.Agric.Food.Chem_52_5340 Purification and characterization of acetylcholinesterase from oriental fruit fly [Bactrocera dorsalis (Hendel)] (Diptera: Tephritidae)
Hu_2004_J.AOAC.Int_87_972 Determination of multiclass pesticide residues in apple juice by gas chromatography-mass selective detection after extraction by matrix solid-phase dispersion
Huang_2004_Lipids_39_251 Purification and characterization of an extracellular lipase from Geotrichum marinum
Ikeda_2004_Tohoku.J.Exp.Med_203_353 Supplementation of antioxidants prevents oxidative stress during a deep saturation dive
Ilinskaya_2004_Med.Sci.Monit_10_BR294 Cytotoxic and genotoxic effects of ss-(triphenylpho-s-phonio)ethyl carboxylate and of N,N'-bis(dihexylphos-phinoylmethyl)-1,4-diaminocyclohexane
Ishii_2004_Folia.Histochem.Cytobiol_42_77 Dendritic spinules in rat nigral neurons revealed by acetylcholinesterase immunocytochemistry and serial sections of the dendritic spine heads
Ishikawa_2004_Asian.Cardiovasc.Thorac.Ann_12_250 What influences the results in critical patients after cardiovascular surgery?
Jakubowski_2004_J.Anal.Toxicol_28_357 Quantitation of fluoride ion released sarin in red blood cell samples by gas chromatography-chemical ionization mass spectrometry using isotope dilution and large-volume injection
Janousek_2004_Transplant.Proc_36_1099 Modulating amylase and lipase secretion in the pancreatic graft by somatostatin administration: preliminary results of a prospective, randomized trial
Jarrard_2004_Aquat.Toxicol_69_133 Impacts of carbamate pesticides on olfactory neurophysiology and cholinesterase activity in coho salmon (Oncorhynchus kisutch)
Jayawardena_2004_Anat.Embryol.(Berl)_208_281 Histochemical localization of cholinesterase activity in the dental epithelium of guinea pig teeth
Jin_2004_Acta.Pharmacol.Sin_25_1013 Overexpression of acetylcholinesterase inhibited cell proliferation and promoted apoptosis in NRK cells
Jinghui_2004_Zhong.Yao.Cai_27_261 [Effects of metabolites of mangrove fungus Xylaria sp. from South China Sea Coast on the activity of acetylcholinesterase in vitro]
Johansen_2004_Diabetologia_47_1437 Large-scale studies of the functional K variant of the butyrylcholinesterase gene in relation to Type 2 diabetes and insulin secretion
Johnson_2004_Biochem.Biophys.Res.Commun_319_448 Identification of a structural site on acetylcholinesterase that promotes neurite outgrowth and binds laminin-1 and collagen IV
Jones_2004_Bioessays_26_39 Functional genomics of the nicotinic acetylcholine receptor gene family of the nematode, Caenorhabditis elegans
Kalman_2004_Atherosclerosis_173_145 Serum butyrylcholinesterase activity in hyperlipidaemia
Kalman_2004_Life.Sci_75_1195 Increased serum butyrylcholinesterase activity in type IIb hyperlipidaemic patients
Kamel_2004_Environ.Health.Perspect_112_950 Association of pesticide exposure with neurologic dysfunction and disease
Karki_2004_Singapore.Med.J_45_385 Cardiac and electrocardiographical manifestations of acute organophosphate poisoning
Kaufer_2004_Acta.Psychiatr.Scand_110_73 A case study in the treatment of dementia with Lewy bodies
Khang_2004_J.Am.Med.Dir.Assoc_5_249 The use, benefits, and costs of cholinesterase inhibitors for Alzheimer's dementia in long-term care: are the data relevant and available?
Kihara_2004_Acta.Neurobiol.Exp.(Wars)_64_99 Alzheimer's disease and acetylcholine receptors
Kitajima_2004_Diabetologia_47_1202 Overexpression of lipoprotein lipase improves insulin resistance induced by a high-fat diet in transgenic rabbits
Knosche_2004_Biosens.Bioelectron_20_153 Molecular recognition of cocaine by acetylcholinesterases for affinity purification and bio-sensing
Koo_2004_Life.Sci_75_2363 A water extract of Curcuma longa L. (Zingiberaceae) rescues PC12 cell death caused by pyrogallol or hypoxia\/reoxygenation and attenuates hydrogen peroxide induced injury in PC12 cells
Kousba_2004_Toxicol.Sci_80_239 Comparison of chlorpyrifos-oxon and paraoxon acetylcholinesterase inhibition dynamics: potential role of a peripheral binding site
Krieger_2004_Environ.Health.Perspect_112_A724 Activities and organophosphate exposures: need for the numbers
Kuca_2004_J.Enzyme.Inhib.Med.Chem_19_39 Reactivation of cyclosarin-inhibited rat brain acetylcholinesterase by pyridinium--oximes
Kudo_2004_Seishin.Shinkeigaku.Zasshi_106_62 [Drug therapy for aged patients with Alzheimer disease]
Kupfermann_2004_J.Anal.Toxicol_28_242 Rapid and sensitive quantitative analysis of alkyl phosphates in urine after organophosphate poisoning
Kurz_2004_Dement.Geriatr.Cogn.Disord_18_217 Ginkgo biloba compared with cholinesterase inhibitors in the treatment of dementia: a review based on meta-analyses by the cochrane collaboration
Lal_2004_Mem.Inst.Oswaldo.Cruz_99_219 Evaluation of cholinesterase level in an endemic population exposed to malathion suspension formulation as a vector control measure
Lane_2004_Clin.Neuropharmacol_27_141 Acetylcholinesterase and its inhibition in Alzheimer disease
Larsen_2004_Pediatr.Pulmonol_38_97 Mechanisms determining cholinergic neural responses in airways of young and mature rabbits
Larsen_2004_Anat.Embryol.(Berl)_208_239 The anatomy of the porcine subthalamic nucleus evaluated with immunohistochemistry and design-based stereology
Larsen_2004_Biochemistry_43_8067 Crystallographic and biochemical analysis of cocaine-degrading antibody 15A10
Larsson_2004_Angew.Chem.Int.Ed.Engl_43_3716 Catalytic self-screening of cholinesterase substrates from a dynamic combinatorial thioester library
Lazarini_2004_Neurotoxicol.Teratol_26_607 Prenatal exposure to dichlorvos: physical and behavioral effects on rat offspring
Lee_2004_Toxicology_201_51 N-nitroso metabolite of carbofuran induces apoptosis in CHL cells by cytochrome c-mediated activation of caspases
Lefebvre_2004_Development_131_2605 Increased neuromuscular activity causes axonal defects and muscular degeneration
Li_2004_Acta.Pharmacol.Sin_25_861 Effects of tanshinone on neuropathological changes induced by amyloid beta-peptide(1-40) injection in rat hippocampus
Li_2004_Toxicology_201_209 Elevated frequency of sister chromatid exchanges of lymphocytes in sarin-exposed victims of the Tokyo sarin disaster 3 years after the event
Li_2004_Hepatobiliary.Pancreat.Dis.Int_3_241 Effect of acute alcoholism on hepatic enzymes and oxidation\/antioxidation in rats
Liang_2004_Neurosci.Lett_361_56 Comparative effects of huperzine A, donepezil and rivastigmine on cortical acetylcholine level and acetylcholinesterase activity in rats
Lim_2004_Biotech.Histochem_79_11 A method for acetylcholinesterase staining of brain sections previously processed for receptor autoradiography
Loewenstein_2004_Am.J.Geriatr.Psychiatry_12_395 Cognitive rehabilitation of mildly impaired Alzheimer disease patients on cholinesterase inhibitors
Luo_2004_Zhonghua.Shi.Yan.He.Lin.Chuang.Bing.Du.Xue.Za.Zhi_18_186 [Clinical research on the effect of Oxymatrine on serum cholinesterase]
Malczewska-Malec_2004_Clin.Chem.Lab.Med_42_487 Analysis of candidate genes in Polish families with obesity
Mareska_2004_Semin.Neurol_24_149 Lambert-Eaton myasthenic syndrome
Marksteiner_2004_Drugs.Aging_21_415 Treatment strategies in Alzheimer's disease with a focus on early pharmacological interventions
Masdeu_2004_Rev.Neurol_38_1156 [Neuroimaging in Alzheimer's disease: an overview]
Mateo_2004_Biotechnol.Bioeng_86_273 A new, mild cross-linking methodology to prepare cross-linked enzyme aggregates
Matsui_2004_FEBS.Lett_569_195 A tomato lipase homologous to DAD1 (LeLID1) is induced in post-germinative growing stage and encodes a triacylglycerol lipase
McPartland_2004_J.Am.Osteopath.Assoc_104_244 Travell trigger points--molecular and osteopathic perspectives
Meier_2004_J.Med.Chem_47_2839 Interaction of cycloSal-pronucleotides with cholinesterases from different origins. A structure-activity relationship
Mesulam_2004_Learn.Mem_11_43 The cholinergic lesion of Alzheimer's disease: pivotal factor or side show?
Millan_2004_J.Pharmacol.Exp.Ther_311_190 The serotonin1A receptor partial agonist S15535 [4-(benzodioxan-5-yl)1-(indan-2-yl)piperazine] enhances cholinergic transmission and cognitive function in rodents: a combined neurochemical and behavioral analysis
Miller_2004_Curr.Opin.Cardiol_19_380 Genetic determinants of low high-density lipoprotein cholesterol
Miller_2004_J.Sports.Sci_22_365 The effects of protease supplementation on skeletal muscle function and DOMS following downhill running
Miyazawa_2004_J.Agric.Food.Chem_52_4401 Insecticidal effect of phthalides and furanocoumarins from Angelica acutiloba against Drosophila melanogaster
Moretti_2004_Expert.Opin.Pharmacother_5_1399 Rivastigmine in vascular dementia
Moretti_2004_Int.J.Clin.Pract_58_346 Rivastigmine superior to aspirin plus nimodipine in subcortical vascular dementia: an open, 16-month, comparative study
Moretto_2004_J.Trace.Elem.Med.Biol_17_255 Effect of subchronic treatment with mercury chloride on NTPDase, 5'-nucleotidase and acetylcholinesterase from cerebral cortex of rats
Morgan_2004_Biochem.J_382_441 Identification of phospholipase B from Dictyostelium discoideum reveals a new lipase family present in mammals, flies and nematodes, but not yeast
Mortele_2004_Abdom.Imaging_29_109 Asymptomatic nonspecific serum hyperamylasemia and hyperlipasemia: spectrum of MRCP findings and clinical implications
Mossello_2004_Arch.Gerontol.Geriatr.Suppl__297 Effectiveness and safety of cholinesterase inhibitors in elderly subjects with Alzheimer's disease: a real world study
Mullner_2004_Acta.Biochim.Pol_51_323 Dynamics of neutral lipid storage in yeast
Murakami_2004_World.J.Surg_28_671 Changes in liver enzymes after surgery in anti-hepatitis C virus-positive patients
Nakagawa_2004_Xenobiotica_34_257 Biotransformation of chlorpropham (CIPC) in isolated rat hepatocytes and xenoestrogenic activity of CIPC and its metabolites by in vitro assays
Nakagawa_2004_Toxicology_200_123 Chlorpropham induces mitochondrial dysfunction in rat hepatocytes
Newmark_2004_Arch.Neurol_61_649 Therapy for nerve agent poisoning
Newmark_2004_N.Engl.J.Med_350_2102 Acute chemical emergencies
O'Neill_2004_Mar.Environ.Res_58_327 Evaluation of toxicity in tributaries of the Mersey estuary using the isopod Asellus aquaticus (L.)
Ota_2004_Ann.Nucl.Med_18_187 A simple method for the detection of abnormal brain regions in Alzheimer's disease patients using [11C]MP4A: comparison with [123I]IMP SPECT
Palomo_2004_J.Chromatogr.A_1038_267 Use of immobilized lipases for lipase purification via specific lipase-lipase interactions
Parihar_2004_J.Clin.Neurosci_11_456 Alzheimer's disease pathogenesis and therapeutic interventions
Park_2004_Am.J.Clin.Nutr_80_45 Triacylglycerol-rich lipoprotein margination: a potential surrogate for whole-body lipoprotein lipase activity and effects of eicosapentaenoic and docosahexaenoic acids
Pavillard_2004_Anticancer.Res_24_579 Cellular parameters predictive of the clinical response of colorectal cancers to irinotecan. A preliminary study
Perez_2004_Mar.Environ.Res_58_275 Biomarker responses to pollution in two invertebrate species: Scrobicularia plana and Nereis diversicolor from the Cadiz bay (SW Spain)
Perona_2004_J.Agric.Food.Chem_52_4227 Virgin olive oil normalizes the altered triacylglycerol molecular species composition of adipose tissue in spontaneously hypertensive rats
Perry_2004_Neoplasia_6_279 CREB regulates AChE-R-induced proliferation of human glioblastoma cells
Perry_2004_Leuk.Res_28_905 Organophosphate risk of leukemogenesis
Pick_2004_Ann.N.Y.Acad.Sci_1018_85 From brain to blood: alternative splicing evidence for the cholinergic basis of Mammalian stress responses
Pitkala_2004_Int.Psychogeriatr_16_61 Behavioral symptoms and the administration of psychotropic drugs to aged patients with dementia in nursing homes and in acute geriatric wards
Platel_2004_Indian.J.Med.Res_119_167 Digestive stimulant action of spices: a myth or reality?
Quinlan_2004_J.Neurophysiol_92_1536 Cholinergic modulation of the locomotor network in the lamprey spinal cord
Raina_2004_Acta.Neurobiol.Exp.(Wars)_64_107 Alzheimer's disease and the cell cycle
Raku_2004_Biotechnol.Lett_26_665 Chemoenzymatic synthesis of optically active, biodegradable polymers based on phenyl- and naphthyl-ethanols esterified with divinyladipate
Rampello_2004_Arch.Gerontol.Geriatr_39_1 Dementia with Lewy bodies: a review
Rawn_2004_Food.Addit.Contam_21_555 N-methyl carbamate concentrations and dietary intake estimates for apple and grape juices available on the retail market in Canada
Reiner_2004_Arh.Hig.Rada.Toksikol_55_1 Activity of cholinesterases in human whole blood measured with acetylthiocholine as substrate and ethopropazine as selective inhibitor of plasma butyrylcholinesterase
Renner_2004_Environ.Health.Perspect_112_A345 Contentious worker testing
Reyes_2004_Am.J.Pathol_164_2163 Acetylcholinesterase-Abeta complexes are more toxic than Abeta fibrils in rat hippocampus: effect on rat beta-amyloid aggregation, laminin expression, reactive astrocytosis, and neuronal cell loss
Richartz_2004_Dtsch.Med.Wochenschr_129_1434 [Psychotropic drug treatment in dementia disorders]
Riegert_2004_Behav.Brain.Res_152_23 Electrolytic lesions of the ventral subiculum weakly alter spatial memory but potentiate amphetamine-induced locomotion
Rodriguez-Fuentes_2004_Mar.Environ.Res_58_505 Characterization of cholinesterase activity from different tissues of Nile tilapia (Oreochromis niloticus)
Rogawski_2004_CNS.Spectr_9_6 What is the rationale for new treatment strategies in Alzheimer's disease?
Saperstein_2004_Semin.Neurol_24_41 Management of myasthenia gravis
Sato_2004_J.Cereb.Blood.Flow.Metab_24_600 Evaluation of simplified kinetic analyses for measurement of brain acetylcholinesterase activity using N-[11C]Methylpiperidin-4-yl propionate and positron emission tomography
Savelev_2004_Phytother.Res_18_315 Butyryl- and acetyl-cholinesterase inhibitory activities in essential oils of Salvia species and their constituents
Saykin_2004_Brain_127_1574 Cholinergic enhancement of frontal lobe activity in mild cognitive impairment
Schmidt_2004_Wien.Klin.Wochenschr_116_235 Normal regulation of elevated plasma ghrelin concentrations in dialysis patients
Scott_2004_Aquat.Toxicol_68_369 The effects of environmental pollutants on complex fish behaviour: integrating behavioural and physiological indicators of toxicity
Sekiya_2004_J.Biol.Chem_279_15084 Absence of hormone-sensitive lipase inhibits obesity and adipogenesis in Lep ob\/ob mice
Sevelova_2004_Cent.Eur.J.Public.Health_12 Suppl_S80 Relationship between plasmatic levels of sarin and cholinesterase inhibition in rats exposed to sarin vapors
Sevelova_2004_Inhal.Toxicol_16_531 Protective effect of equine butyrylcholinesterase in inhalation intoxication of rats with sarin: determination of blood and brain cholinesterase activities
Shaonan_2004_Aquat.Toxicol_68_293 Kinetic characters and resistance to inhibition of crude and purified brain acetylcholinesterase of three freshwater fishes by organophosphates
Shen_2004_Chembiochem_5_921 A mass spectrometry plate reader: monitoring enzyme activity and inhibition with a Desorption\/Ionization on Silicon (DIOS) platform
Shen_2004_Med.Hypotheses_63_285 Brain cholinesterases: I. The clinico-histopathological and biochemical basis of Alzheimer's disease
Shen_2004_Med.Hypotheses_63_298 Brain cholinesterases: III. Future perspectives of AD research and clinical practice
Sheu_2004_J.Bacteriol_186_4177 Altering the substrate specificity of polyhydroxyalkanoate synthase 1 derived from Pseudomonas putida GPo1 by localized semirandom mutagenesis
Shimojima_2004_Clin.Rheumatol_23_262 Efficacy of tacrolimus in treatment of polymyositis associated with myasthenia gravis
Singh_2004_Indian.J.Exp.Biol_42_292 In vitro effects of organophosphate pesticides on rat erythrocytes
Slotkin_2004_Toxicol.Appl.Pharmacol_198_132 Cholinergic systems in brain development and disruption by neurotoxicants: nicotine, environmental tobacco smoke, organophosphates
Smith_2004_J.Anal.Toxicol_28_390 Analysis of the enantiomers of VX using normal-phase chiral liquid chromatography with atmospheric pressure chemical ionization-mass spectrometry
Sobrado_2004_Neurosci.Lett_365_132 Galantamine and memantine produce different degrees of neuroprotection in rat hippocampal slices subjected to oxygen-glucose deprivation
Solini_2004_J.Intern.Med_256_30 Lipoprotein lipase gene variants and progression of nephropathy in hypercholesterolaemic patients with type 2 diabetes
Song_2004_Biochem.Biophys.Res.Commun_319_1072 Intramolecular disulfide bonds are required for folding hydrolase B into a catalytically active conformation but not for maintaining it during catalysis
Srinivas_2004_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_137_261 Identification of factors responsible for insecticide resistance in Helicoverpa armigera
Standridge_2004_Clin.Ther_26_615 Pharmacotherapeutic approaches to the treatment of Alzheimer's disease
Stella_2004_Emerg.Med.Australas_16_235 Glyphosate herbicide formulation: a potentially lethal ingestion
Takasaki_2004_J.Pharmacol.Sci_95_291 Effects of combination treatment with dipeptidyl peptidase IV inhibitor and sulfonylurea on glucose levels in rats
Tan_2004_Am.J.Pathol_165_319 Adenosine down-regulates the surface expression of dipeptidyl peptidase IV on HT-29 human colorectal carcinoma cells: implications for cancer cell behavior
Tian_2004_Neurosci_126_277 Injection of okadaic acid into the meynert nucleus basalis of rat brain induces decreased acetylcholine level and spatial memory deficit
Tien_2004_Brain.Res.Mol.Brain.Res_126_38 Changes in acetylcholinesterase activity and muscarinic receptor bindings in mu-opioid receptor knockout mice
Timchalk_2004_J.Toxicol.Environ.Health.A_67_635 Noninvasive biomonitoring approaches to determine dosimetry and risk following acute chemical exposure: analysis of lead or organophosphate insecticide in saliva
Tomita_2004_Hepatogastroenterology_51_1042 Histological studies on Hirschsprung's disease and its allied disorders in childhood
Torres_2004_Biotechnol.Prog_20_756 Lipase-catalyzed ethanolysis of borage oil: a kinetic study
Vahdati-Mashhadian_2004_Can.J.Physiol.Pharmacol_82_326 Ethnic differences in the frequency of distribution of serum cholinesterase activity in the Iranian population
van Dyck_2004_CNS.Spectr_9_24 Understanding the latest advances in pharmacologic interventions for Alzheimer's disease
Venalainen_2004_Eur.J.Biochem_271_2705 Evolutionary relationships of the prolyl oligopeptidase family enzymes
Voisin_2004_CNS.Drugs_18_575 What are the treatment options for patients with severe Alzheimer's disease?
Wallin_2004_Dement.Geriatr.Cogn.Disord_18_197 Five-year outcome of cholinergic treatment of Alzheimer's disease: early response predicts prolonged time until nursing home placement, but does not alter life expectancy
Wang_2004_Zhongguo.Zhong.Xi.Yi.Jie.He.Za.Zhi_24_392 [Clinical study on treatment of mild cognitive impairment by modified wuzi yanzong granule]
Wang_2004_Anal.Biochem_329_131 Screening assays for cholinesterases resistant to inhibition by organophosphorus toxicants
Watt_2004_FASEB.J_18_1445 Beta-adrenergic stimulation of skeletal muscle HSL can be overridden by AMPK signaling
Waylan_2004_J.Anim.Sci_82_1868 Effect of flax supplementation and growth promotants on lipoprotein lipase and glycogenin messenger RNA concentrations in finishing cattle
Weston_2004_Environ.Sci.Technol_38_2752 Distribution and toxicity of sediment-associated pesticides in agriculture-dominated water bodies of California's Central Valley
Whyatt_2004_Environ.Health.Perspect_112_1125 Prenatal insecticide exposures and birth weight and length among an urban minority cohort
Wilkinson_2004_Drugs.Aging_21_453 Cholinesterase inhibitors used in the treatment of Alzheimer's disease: the relationship between pharmacological effects and clinical efficacy
Williams_2004_Leuk.Res_28_947 Chromosomal aberrations in human lymphocytes exposed to the anticholinesterase pesticide isofenphos with mechanisms of leukemogenesis
Wilson_2004_Int.J.Toxicol_23_97 Meeting requirements of the California cholinesterase monitoring program
Yamamuro_2004_Exp.Anim_53_145 Functional development of oligodendrocytes and open-field behavior in developing rats: an approach using monoclonal antibody to immature oligodendrocytes
Yeow_2004_J.Biotechnol_111_31 Cleaving of S-mandelonitrile catalyzed by S-hydroxynitrile lyase from Hevea brasiliensis--a kinetic investigation based on the rate curve method
Yu_2004_Sichuan.Da.Xue.Xue.Bao.Yi.Xue.Ban_35_354 [Pathological changes and apoptosis of brain cells in rat embryo suffering from intrauterine hypoxia-ischemic injury]
Yu_2004_Biotechnol.Lett_26_629 Enhanced activity and enantioselectivity of Candida rugosa lipase immobilized on macroporous adsorptive resins for ibuprofen resolution
Zbarsky_2004_Neurobiol.Dis_16_283 Bioactivity of a peptide derived from acetylcholinesterase: involvement of an ivermectin-sensitive site on the alpha 7 nicotinic receptor
Zdrazilova_2004_Z.Naturforsch.C_59_293 Half-inhibition concentrations of new cholinesterase inhibitors
Zhang_2004_Zhejiang.Da.Xue.Xue.Bao.Yi.Xue.Ban_33_205 [Influence of chronic epilepsy on spatial memory retrieval in rats]
Aarab_2004_Biomarkers_9_258 Scoring approach based on fish biomarkers applied to French river monitoring
Agrawal_2004_Mol.Divers_8_413 QSAR study on phosphoramidothioate (Ace) toxicities in housefly
Aguglia_2004_Curr.Med.Res.Opin_20_1747 An open-label, comparative study of rivastigmine, donepezil and galantamine in a real-world setting
Ahren_2004_Diabetes.Care_27_2874 Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes
Ahren_2004_Horm.Metab.Res_36_867 GLP-1 receptor agonists and DPP-4 inhibitors in the treatment of type 2 diabetes
Ajami_2004_Biochim.Biophys.Acta_1679_18 Dipeptidyl peptidase 9 has two forms, a broad tissue distribution, cytoplasmic localization and DPIV-like peptidase activity
Akintade_2004_Lancet_364_1214\; author reply 1216 AD2000: design and conclusions
Akizuki_2004_Clin.Chem.Lab.Med_42_991 Genetic and immunological analyses of patients with increased serum butyrylcholinesterase activity and its C5 variant form
Akoh_2004_Lipids_39_513 Protein engineering and applications of Candida rugosa lipase isoforms
Aldunate_2004_Brain.Res.Brain.Res.Rev_47_96 Structural and functional organization of synaptic acetylcholinesterase
Allain_2004_Lancet.Neurol_3_643 Mild cognitive impairment: a treatment at last?
Allain_2004_Psychol.Neuropsychiatr.Vieil_2_167 [Biology of motivation]
Anitha_2004_Biosens.Bioelectron_20_848 Development of acetylcholinesterase silica sol-gel immobilized biosensor--an application towards oxydemeton methyl detection
Ankarberg_2004_Toxicol.Sci_82_555 Increased susceptibility to adult paraoxon exposure in mice neonatally exposed to nicotine
Arroyo_2004_J.Agric.Food.Chem_52_8066 Hydrolysis of carbaryl by carbonate impurities in reference clay SWy-2
Atta_2004_Steroids_69_735 New pregnane-type steroidal alkaloids from Sarcocca saligna and their cholinesterase inhibitory activity
Azhar_2004_Chem.Pharm.Bull.(Tokyo)_52_1269 Enzyme inhibiting lignans from Vitex negundo
Azoulay_2004_J.Immunol.Methods_295_37 An enzyme immunoassay for the quantification of plasma and intracellular lopinavir in HIV-infected patients
Babic_2004_Coll.Antropol_28_199 ApoE genotyping and response to galanthamine in Alzheimer's disease--a real life retrospective study
Bajgar_2004_Adv.Clin.Chem_38_151 Organophosphates\/nerve agent poisoning: mechanism of action, diagnosis, prophylaxis, and treatment
Baker_2004_J.Med.Chem_47_4693 A prodrug approach toward the development of water soluble fluoroquinolones and structure--activity relationships of quinoline-3-carboxylic acids
Bakr_2004_Pediatr.Nephrol_19_396 5-Lipoxygenase and leukotriene A4 hydrolase expression in primary nephrotic syndrome
Balkanov_2004_Vojnosanit.Pregl_61_659 [Physiological role and clinical significance of serum cholinesterase]
Bannerman_2004_Behav.Neurosci_118_1033 Medial septal lesions mimic effects of both selective dorsal and ventral hippocampal lesions
Bansal_2004_Pest.Manag.Sci_60_1149 Kinetics of interaction of three carbamate pesticides with Indian soils: Aligarh district
Barcikowska_2004_Folia.Neuropathol_42_251 New therapeutic approaches in Alzheimer's disease
Barends_2004_Curr.Opin.Biotechnol_15_356 Three-dimensional structures of enzymes useful for beta-lactam antibiotic production
Bavdekar_2004_Ann.Pharmacother_38_1648 Anticonvulsant hypersensitivity syndrome: lymphocyte toxicity assay for the confirmation of diagnosis and risk assessment
Bebianno_2004_Biomarkers_9_305 Biomarkers in Ruditapes decussatus: a potential bioindicator species
Belinskaya_2004_Dokl.Biochem.Biophys_396_146 Productive substrate sorption in acetylcholinesterase and butyrylcholinesterase active sites according to theoretical conformational analysis
Bergander_2004_Chem.Biol.Interact_149_151 Metabolic fate of the Ah receptor ligand 6-formylindolo[3,2-b]carbazole
Beschorner_2004_Folia.Neuropathol_42_191 Problems in fast intraoperative diagnosis in Hirschsprung's disease
Beusterien_2004_CNS.Drugs_18_1143 Impact of rivastigmine use on the risk of nursing home placement in a US sample
Bigbee_2004_Neurochem.Res_29_2043 The adhesive role of acetylcholinesterase (AChE): detection of AChE binding proteins in developing rat spinal cord
Bjorklund_2004_Rapid.Commun.Mass.Spectrom_18_3079 Selective determination of organophosphate flame retardants and plasticizers in indoor air by gas chromatography, positive-ion chemical ionization and collision-induced dissociation mass spectrometry
Blacker_2004_JAMA_292_1195 Effect of galantamine hydrobromide in chronic fatigue syndrome: a randomized controlled trial
Bodin_2004_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_138_411 Seasonal variations of a battery of biomarkers and physiological indices for the mussel Mytilus galloprovincialis transplanted into the northwest Mediterranean Sea
Boman_2004_Ann.Pathol_24_486 [Hirschsprung's disease: practical considerations]
Bondarenko_2004_Environ.Toxicol.Chem_23_2649 Persistence of selected organophosphate and carbamate insecticides in waters from a coastal watershed
Bonfanti_2004_Aquat.Toxicol_70_189 Comparative teratogenicity of chlorpyrifos and malathion on Xenopus laevis development
Bonnet_2004_J.Am.Mosq.Control.Assoc_20_438 Topical applications of pyrethroid and organophosphate mixtures revealed positive interactions against pyrethroid-resistant Anopheles gambiae
Booth_2004_Chem.Biol.Interact_147_213 Dose responses for the formation of hemoglobin adducts and urinary metabolites in rats and mice exposed by inhalation to low concentrations of 1,3-[2,3-(14)C]-butadiene
Borkovcova_2004_Cent.Eur.J.Public.Health_12_220 Determination of n-methylcarbamates in foods
Bosboom_2004_J.Neural.Transm.(Vienna)_111_1303 Cognitive dysfunction and dementia in Parkinson's disease
Broedl_2004_FASEB.J_18_1891 Structural basis of endothelial lipase tropism for HDL
Brun_2004_J.Immunol.Methods_295_21 Enzyme-linked immunosorbent assay for the organophosphorus insecticide fenthion. Influence of hapten structure
Buckley_2004_BMJ_329_1231 Overcoming apathy in research on organophosphate poisoning
Cabal_2004_Basic.Clin.Pharmacol.Toxicol_95_81 Specification of the structure of oximes able to reactivate tabun-inhibited acetylcholinesterase
Cabal_2004_Acta.Medica.(Hradec.Kralove)_47_115 Cyclodextrines as functional agents for decontamination of the skin contaminated by nerve agents
Caldas_2004_Food.Addit.Contam_21_1057 Chronic dietary risk for pesticide residues in food in Brazil: an update
Camargo_2004_Biomedica_24_345 A quantitative method for analysing neuron networks marked by acetylcholinesterase histochemistry
Cardoso_2004_J.Nat.Prod_67_1882 Indole glucoalkaloids from Chimarrhis turbinata and their evaluation as antioxidant agents and acetylcholinesterase inhibitors
Caricati-Neto_2004_Eur.J.Pharmacol_503_191 Enhancement of purinergic neurotransmission by galantamine and other acetylcholinesterase inhibitors in the rat vas deferens
Carlacci_2004_Biophys.Chem_111_143 Conformational energy landscape of the acyl pocket loop in acetylcholinesterase: a Monte Carlo-generalized Born model study
Carnahan_2004_J.Am.Geriatr.Soc_52_2082 The concurrent use of anticholinergics and cholinesterase inhibitors: rare event or common practice?
Carpentier_2004_Drug.Chem.Toxicol_27_213 Flunarizine: a possible adjuvant medication against soman poisoning?
Caruso_2004_Clin.Cancer.Res_10_222 Altered N-myc downstream-regulated gene 1 protein expression in African-American compared with caucasian prostate cancer patients
Carvalho_2004_J.Appl.Toxicol_24_419 Acetylcholine and choline effects on erythrocyte nitrite and nitrate levels
Carvalho_2004_Rev.Saude.Publica_38_623 [Susceptibility of Aedes aegypti larvae to the insecticide temephos in the Federal District, Brazil]
Castro_2004_Ecotoxicology_13_667 An in situ bioassay integrating individual and biochemical responses using small fish species
Chaize_2004_Biosens.Bioelectron_20_628 Sorting out molecules reacting with acetylcholinesterase by enzyme encapsulation in liposome
Chang_2004_Shock_22_575 De novo synthesis of ubiquitin carboxyl-terminal hydrolase isozyme l1 in rostral ventrolateral medulla is crucial to survival during mevinphos intoxication
Chapman_2004_J.Speech.Lang.Hear.Res_47_1149 Effects of cognitive-communication stimulation for Alzheimer's disease patients treated with donepezil
Chen_2004_Curr.Cancer.Drug.Targets_4_267 Leukotriene A4 hydrolase as a target for cancer prevention and therapy
Cheng_2004_Eur.Respir.J_23_818 Genetic polymorphism of epoxide hydrolase and glutathione S-transferase in COPD
Cheol_2004_J.Med.Food_7_436 Anti-hepatotoxic effects of Rosa rugosa root and its compound, rosamultin, in rats intoxicated with bromobenzene
Chih_2004_Hum.Mol.Genet_13_1471 Disorder-associated mutations lead to functional inactivation of neuroligins
Choi_2004_Eur.J.Pharmacol_505_83 Protection by sustained release of physostigmine and procyclidine of soman poisoning in rats
Choi_2004_Drug.Metabol.Drug.Interact_20_233 Inhibition of trans-permethrin hydrolysis in human liver fractions by chloropyrifos oxon and carbaryl
Chou_2004_Neurosci.Lett_370_123 Lateral hypothalamic acetylcholinesterase-immunoreactive neurons co-express either orexin or melanin concentrating hormone
Choudhary_2004_Chem.Pharm.Bull.(Tokyo)_52_1358 Cholinesterase inhibiting withanolides from Withania somnifera
Clark_2004_J.Toxicol.Clin.Toxicol_42_991 A reassessment of topical organic phosphorus insecticide exposures and permanent paralysis
Clarke_2004_Lancet_364_1215 AD2000: design and conclusions
Colombres_2004_Curr.Pharm.Des_10_3121 An overview of the current and novel drugs for Alzheimer's disease with particular reference to anti-cholinesterase compounds
Comoletti_2004_J.Neurosci_24_4889 The Arg451Cys-neuroligin-3 mutation associated with autism reveals a defect in protein processing
Corsetti_2004_Gut_53_1787 The role of tension receptors in colonic mechanosensitivity in humans
Corsois_2004_Ann.Pathol_24_407 [Synaptophysin expression abnormalities in Hirschsprung's disease]
Cossu_2004_Mov.Disord_19_1243 Reversible Pisa syndrome (pleurothotonus) due to the cholinesterase inhibitor galantamine: case report
Cuthbert_2004_Gut_53_1386 Genetic association between EPHX1 and Crohn's disease: population stratification, genotyping error, or random chance?
da Silva_2004_J.Ethnopharmacol_95_199 Memory retrieval improvement by Ptychopetalum olacoides in young and aging mice
Dahlgren_2004_J.Toxicol.Clin.Toxicol_42_579 Health effects of diazinon on a family
Dalvi_2004_Vet.Hum.Toxicol_46_297 Cytochrome P450-mediated activation and toxicity of chlorpyrifos in male and female rats
Damiens_2004_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_138_121 Evaluation of biomarkers in oyster larvae in natural and polluted conditions
Davanzo_2004_Epidemiol.Prev_28_330 [Agricultural pesticide-related poisonings in Italy: cases reported to the Poison Control Centre of Milan in 2000-2001]
de Oliveira Marques_2004_Biosens.Bioelectron_20_825 Comparative investigation between acetylcholinesterase obtained from commercial sources and genetically modified Drosophila melanogaster: application in amperometric biosensors for methamidophos pesticide detection
Deacon_2004_Horm.Metab.Res_36_761 Circulation and degradation of GIP and GLP-1
Delgado_2004_Scand.J.Work.Environ.Health_30_362 Central nervous system effects of acute organophosphate poisoning in a two-year follow-up
Desai_2004_CNS.Drugs_18_853 Activities of daily living in patients with dementia: clinical relevance, methods of assessment and effects of treatment
Devillers_2004_SAR.QSAR.Environ.Res_15_501 Prediction of mammalian toxicity of organophosphorus pesticides from QSTR modeling
Di Angelantonio_2004_Neurosci.Lett_369_208 Methamidophos transiently inhibits neuronal nicotinic receptors of rat substantia nigra dopaminergic neurons via open channel block
Dirksen_2004_Pediatr.Res_55_466 Glutathione S transferase theta 1 gene (GSTT1) null genotype is associated with an increased risk for acquired aplastic anemia in children
Doderer_2004_Biotechnol.Lett_26_835 Fluorometric assay for determining epoxide hydrolase activity
Doerr_2004_Pest.Manag.Sci_60_1025 Integrated pest management approach for a new pest, Lacanobia subjuncta (Lepidoptera: Noctuidae), in Washington apple orchards
Dominguez_2004_Biotechnol.Lett_26_1517 Unexpected reaction profile observed in the synthesis of propyl laurate when using Candida rugosa lipases immobilized in microemulsions based organogels
Dong_2004_J.Neurosci_24_8950 Excessive expression of acetylcholinesterase impairs glutamatergic synaptogenesis in hippocampal neurons
Du_2004_Curr.Pharm.Des_10_3141 Development of bivalent acetylcholinesterase inhibitors as potential therapeutic drugs for Alzheimer's disease
DuTeaux_2004_Toxicol.Sci_78_187 Epoxide hydrolases in the rat epididymis: possible roles in xenobiotic and endogenous fatty acid metabolism
Ebell_2004_Am.Fam.Physician_70_1681 Donepezil in the treatment of vascular dementia
Eddleston_2004_Crit.Care_8_R391 Early management after self-poisoning with an organophosphorus or carbamate pesticide - a treatment protocol for junior doctors
Edmondson_2004_Bioorg.Med.Chem.Lett_14_5151 Potent and selective proline derived dipeptidyl peptidase IV inhibitors
El-Demerdash_2004_J.Trace.Elem.Med.Biol_18_113 Antioxidant effect of vitamin E and selenium on lipid peroxidation, enzyme activities and biochemical parameters in rats exposed to aluminium
Elrod_2004_Ophthalmol.Clin.North.Am_17_275 Ocular myasthenia gravis
Emre_2004_N.Engl.J.Med_351_2509 Rivastigmine for dementia associated with Parkinson's disease
Erkinjuntti_2004_J.Neurol.Sci_226_63 Treatment of vascular dementia--evidence from clinical trials with cholinesterase inhibitors
Feliciello_2004_Nutr.Metab.Cardiovasc.Dis_14_205 Pair-wise detection of eight common DNA polymorphisms of the human lipoprotein lipase gene by PCR-RFLP. Findings of the Olivetti Heart Study
Fellers_2004_Environ.Toxicol.Chem_23_2170 Pesticides in mountain yellow-legged frogs (Rana muscosa) from the Sierra Nevada Mountains of California, USA
Feng_2004_J.Pineal.Res_37_198 Long-term effects of melatonin or 17 beta-estradiol on improving spatial memory performance in cognitively impaired, ovariectomized adult rats
Ferrari_2004_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_139_239 Different susceptibility of two aquatic vertebrates (Oncorhynchus mykiss and Bufo arenarum) to azinphos methyl and carbaryl
Finucane_2004_N.Engl.J.Med_351_1911 Drug therapy in Alzheimer's disease
Fletcher_2004_Plant.Mol.Biol_55_33 Tissue distribution of cholinesterases and anticholinesterases in native and transgenic tomato plants
Fodale_2004_Anesthesiology_101_1483 Cholinesterase inhibitors, neuromuscular blocking drugs and perioperative memory enhancement
Foil_2004_Vet.Parasitol_125_163 Factors that influence the prevalence of acaricide resistance and tick-borne diseases
Forman_2004_J.Vet.Intern.Med_18_807 Evaluation of serum feline pancreatic lipase immunoreactivity and helical computed tomography versus conventional testing for the diagnosis of feline pancreatitis
Foster_2004_FEMS.Microbiol.Lett_240_49 Microbial degradation of the organophosphate pesticide, Ethion
Fred_2004_Chem.Res.Toxicol_17_785 Hemoglobin adduct levels in rat and mouse treated with 1,2:3,4-diepoxybutane
Fuchs_2004_J.Neurol_251 Suppl 6_VI\/28 Dementia in idiopathic Parkinson's syndrome
Fuentealba_2004_Brain.Res.Brain.Res.Rev_47_275 Signal transduction during amyloid-beta-peptide neurotoxicity: role in Alzheimer disease
Fuentes_2004_Protein.Sci_13_3092 Specificity in lipases: a computational study of transesterification of sucrose
Gagne_2004_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_138_515 Shell protein characteristics and vitellogenin-like proteins in brine shrimp Artemia franciscana exposed to municipal effluent and 20-hydroxyecdysone
Ganguli_2004_J.Am.Geriatr.Soc_52_1668 Detection and management of cognitive impairment in primary care: The Steel Valley Seniors Survey
Gao_2004_J.Ind.Microbiol.Biotechnol_31_525 Optimization of Serratia marcescens lipase production for enantioselective hydrolysis of 3-phenylglycidic acid ester
Garcia_2004_Brain.Res_1026_313 AChE-rich magnopyramidal neurons have a left-right size asymmetry in Broca's area
Garcon_2004_Toxicol.Lett_150_179 Effect of Fe(2)O(3) on the capacity of benzo(a)pyrene to induce polycyclic aromatic hydrocarbon-metabolizing enzymes in the respiratory tract of Sprague-Dawley rats
Garg_2004_Int.Immunopharmacol_4_1709 Haemato-biochemical and immuno-pathophysiological effects of chronic toxicity with synthetic pyrethroid, organophosphate and chlorinated pesticides in broiler chicks
Geen_2004_Autoimmunity_37_579 The prevalence of anti-acetylcholinesterase antibodies in autoimmune disease
Genter_2004_J.Biochem.Mol.Toxicol_18_239 Update on olfactory mucosal metabolic enzymes: age-related changes and N-acetyltransferase activities
Georgiadis_2004_Toxicol.Lett_149_269 Impact of phase I or phase II enzyme polymorphisms on lymphocyte DNA adducts in subjects exposed to urban air pollution and environmental tobacco smoke
Geula_2004_Drugs.Today.(Barc)_40_711 Butyrylcholinesterase, cholinergic neurotransmission and the pathology of Alzheimer's disease
Gholivand_2004_J.Enzyme.Inhib.Med.Chem_19_403 Acetylcholinesterase inhibition by diaza- and dioxophosphole compounds: synthesis and determination of IC50 values
Glueck_2004_Chemistry_10_3467 Biocatalytic asymmetric rearrangement of a methylene-interrupted bis-epoxide: simultaneous control of four asymmetric centers through a biomimetic reaction cascade
Gold_2004_Praxis.(Bern.1994)_93_1311 [Diagnosis and treatment of vascular dementia]
Gondret_2004_Lipids.Health.Dis_3_27 Unusual metabolic characteristics in skeletal muscles of transgenic rabbits for human lipoprotein lipase
Gouedard_2004_Arterioscler.Thromb.Vasc.Biol_24_2378 Induction of the paraoxonase-1 gene expression by resveratrol
Graf_2004_Cell_119_1013 Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins
Groisman_2004_J.Environ.Qual_33_1930 Sorption and detoxification of toxic compounds by a bifunctional organoclay
Gu_2004_Zhonghua.Lao.Dong.Wei.Sheng.Zhi.Ye.Bing.Za.Zhi_22_388 [Gastric lavage for organophosphate pesticides poisoning patients]
Guo_2004_J.Med.Chem_47_5492 A docking score function for estimating ligand-protein interactions: application to acetylcholinesterase inhibition
Guven_2004_J.Toxicol.Clin.Toxicol_42_617 The effects of fresh frozen plasma on cholinesterase levels and outcomes in patients with organophosphate poisoning
Habalova_2004_Neoplasma_51_352 Combined analysis of polymorphisms in glutathione S-transferase M1 and microsomal epoxide hydrolase in lung cancer patients
Haeggstrom_2004_J.Biol.Chem_279_50639 Leukotriene A4 hydrolase\/aminopeptidase, the gatekeeper of chemotactic leukotriene B4 biosynthesis
Hajek_2004_Biomed.Pap.Med.Fac.Univ.Palacky.Olomouc.Czech.Repub_148_209 Comparison of changes in AChE activity in the brain of the laboratory rat after soman and tabun intoxication
Hamamoto_2004_Radiat.Med_22_316 Impact of pretreatment cholinesterase level on survival of inoperable intrahepatic or hepatic-hilar carcinomas treated with three-dimensional conformal radiotherapy
Hamilton_2004_Mil.Med_169_856 Clinical aspects of percutaneous poisoning by the chemical warfare agent VX: effects of application site and decontamination
Hantai_2004_Curr.Opin.Neurol_17_539 Congenital myasthenic syndromes
Happe_2004_Brain.Res.Dev.Brain.Res_153_29 Distribution and postnatal development of alpha 7 nicotinic acetylcholine receptors in the rodent lower auditory brainstem
Harrigan_2004_Toxicol.Sci_77_307 DNA adduct formation in precision-cut rat liver and lung slices exposed to benzo[a]pyrene
Hartmann_2004_Chemosphere_57_781 Organophosphate flame retardants and plasticizers in indoor air
Hayashida_2004_Masui_53_1293 [Anesthetic managements of a patient with congenital myotonia (Becker type)]
Himmelstein_2004_Toxicol.Sci_79_18 Kinetic modeling of beta-chloroprene metabolism: I. In vitro rates in liver and lung tissue fractions from mice, rats, hamsters, and humans
Hirabayashi_2004_J.Neurochem_90_332 Synaptic scaffolding molecule interacts with axin
Hiura_2004_Okajimas.Folia.Anat.Jpn_81_75 Capsaicin-resistant, nonspecific acetylcholinesterase (NsAchE) reactive nerve fibers in the rat cornea: a quantitative and developmental study
Hoffman_2004_J.Toxicol.Clin.Toxicol_42_349 Ecgonine methyl ester protects against cocaine lethality in mice
Hogan_2004_Lancet.Neurol_3_622 Comparison studies of cholinesterase inhibitors for Alzheimer's disease
Holmes_2004_Lancet_364_1213 AD2000: design and conclusions
Holst_2004_Horm.Metab.Res_36_747 On the physiology of GIP and GLP-1
Hong_2004_Se.Pu_22_289 [Simultaneous determination of organophosphorus and pyrethroid pesticide residues in vegetables by GC]
Houghton_2004_Phytochemistry_65_2893 Choline esterase inhibitory properties of alkaloids from two Nigerian Crinum species
Howe_2004_Lancet_364_1214 AD2000: design and conclusions
Hsu_2004_J.Econ.Entomol_97_1682 Resistance and synergistic effects of insecticides in Bactrocera dorsalis (Diptera: Tephritidae) in Taiwan
Hutchings_2004_Ecotoxicology_13_475 Toxicity reduction evaluation, toxicity identification evaluation and toxicity tracking in direct toxicity assessment
Hyder_2004_Environ.Toxicol.Chem_23_2856 Influence of developmental stage on susceptibilities and sensitivities of Simulium vittatum IS-7 and Simulium vittatum IIIL-1 (Diptera: Simuliidae) to chlorpyrifos
Ichibangase_2004_Luminescence_19_259 Chemiluminescence assay of lipase activity using a synthetic substrate as proenhancer for luminol chemiluminescence reaction
Ide_2004_Cancer.Lett_214_35 Skin and salivary gland carcinogenicity of 7,12-dimethylbenz[a]anthracene is equivalent in the presence or absence of aryl hydrocarbon receptor
Iida_2004_Mol.Cell.Neurosci_27_497 Synaptic scaffolding molecule is involved in the synaptic clustering of neuroligin
Inkson_2004_Bone_35_819 Characterization of acetylcholinesterase expression and secretion during osteoblast differentiation
Iwasaki_2004_Transplantation_78_1501 Noninvasive evaluation of graft steatosis in living donor liver transplantation
Iwasaki_2004_Adv.Biochem.Eng.Biotechnol_90_151 Enzymatic synthesis of structured lipids
Jackson_2004_Br.J.Clin.Pharmacol_58 Suppl 1_1 The safety and tolerability of donepezil in patients with Alzheimer's disease
Jann_2004_Pharmacotherapy_24_1759 Implications for atypical antipsychotics in the treatment of schizophrenia: neurocognition effects and a neuroprotective hypothesis
Jevsek_2004_Eur.J.Neurosci_20_2865 Origin of acetylcholinesterase in the neuromuscular junction formed in the in vitro innervated human muscle
Jia_2004_Chin.Med.J.(Engl)_117_1161 Differential acetylcholine and choline concentrations in the cerebrospinal fluid of patients with Alzheimer's disease and vascular dementia
Jiang_2004_Biotechnol.Lett_26_1585 Cloning and expression of the polyhydroxyalkanote depolymerase gene from Pseudomonas putida, and characterization of the gene product
Jimenez-Cardoso_2004_Acta.Trop_92_237 In vitro activity of two phenyl-carbamate derivatives, singly and in combination with albendazole against albendazole-resistant Giardia intestinalis
Jirachaiyabhas_2004_Int.J.Occup.Environ.Health_10_289 Organophosphate pesticide exposures of traditional and integrated pest management farmers from working air conditions: a case study in Thailand
Johannsen_2004_CNS.Drugs_18_757 Long-term cholinesterase inhibitor treatment of Alzheimer's disease
Johannsen_2004_Ugeskr.Laeger_166_2916 [Is drug therapy of Alzheimer disease ineffective?]
Jonasson_2004_Eur.J.Neurosci_20_3041 Sexually dimorphic effects of hippocampal cholinergic deafferentation in rats
Joos_2004_Swiss.Med.Wkly_134_437 COPD and genetics--what's new?
Jorda_2004_J.Alzheimers.Dis_6_577 (+\/-)-huprine Y, (-)-huperzine A and tacrine do not show neuroprotective properties in an apoptotic model of neuronal cytoskeletal alteration
Kaduszkiewicz_2004_Fortschr.Neurol.Psychiatr_72_557 [Doubtful evidence for the use of the cholinesterase inhibitor donepezil in patients with dementia--a systematic review]
Kaizer_2004_Neurochem.Res_29_2251 Diet-induced changes in AChE activity after long-term exposure
Kalisvaart_2004_Ned.Tijdschr.Geneeskd_148_1501 [Successful treatment of three elderly patients suffering from prolonged delirium using the cholinesterase inhibitor rivastigmine]
Kallin_2004_Aging.Clin.Exp.Res_16_270 Drugs and falls in older people in geriatric care settings
Kalow_2004_Hum.Genomics_1_375 Human pharmacogenomics: the development of a science
Kassa_2004_Acta.Medica.(Hradec.Kralove)_47_111 The influence of the time of antidotal treatment administration on its effectiveness against tabun-induced poisoning in mice
Kassa_2004_Acta.Medica.(Hradec.Kralove)_47_171 Assessment of the therapeutic and anticonvulsive efficacy of a drug combination consisting of trihexyphenidyle and HI-6 in soman-poisoned rats
Kawaguchi_2004_J.Neurol.Sci_224_43 Treatment and outcome of myasthenia gravis: retrospective multi-center analysis of 470 Japanese patients, 1999-2000
Kijima_2004_Biotechnol.Lett_26_1505 Lipase-catalyzed enantioselective esterification of mono-aza-benzo-15-crown-5-ether derivatives in organic media
Kim_2004_Biosci.Biotechnol.Biochem_68_1977 Effects of green tea polyphenol on cognitive and acetylcholinesterase activities
Kim_2004_J.Pharmacol.Sci_96_314 Effects of methanol extract of Uncariae Ramulus et Uncus on ibotenic acid-induced amnesia in the rat
Kim_2004_Biosci.Biotechnol.Biochem_68_2289 Thermostable esterase from a thermoacidophilic archaeon: purification and characterization for enzymatic resolution of a chiral compound
Kinoshita_2004_Nihon.Rinsho_62 Suppl 12_79 [Hepatic triglyceride lipase (HTGL)]
Kinser_2004_J.Toxicol.Environ.Health.A_67_1423 Gene expression profiling in spleens of deoxynivalenol-exposed mice: immediate early genes as primary targets
Kiss_2004_J.Muscle.Res.Cell.Motil_25_509 Molecular forms of acetylcholinesterase in the rat extensor digitorum longus and soleus muscles regenerating from notexin-induced necrosis
Kita_2004_Chem.Rec_4_363 1-alkoxyvinyl esters: renaissance of half-century-old acyl donors with potential applicability
Kjellgren_2004_Invest.Ophthalmol.Vis.Sci_45_4233 Laminin isoforms in human extraocular muscles
Klajnert_2004_Bioelectrochemistry_65_23 The effect of polyamidoamine dendrimers on human erythrocyte membrane acetylcholinesterase activity
Kobayashi_2004_J.Exp.Biol_207_3757 Electrical and mechanical properties and mode of innervation in scorpionfish sound-producing muscle fibres
Koch_2004_Proc.Natl.Acad.Sci.U.S.A_101_16721 Compound library development guided by protein structure similarity clustering and natural product structure
Kolaczinski_2004_J.Med.Entomol_41_930 Investigation of negative cross-resistance as a resistance-management tool for insecticide-treated nets
Komatsu_2004_Colloids.Surf.B.Biointerfaces_38_175 Interesterification activity of Rhizopus delemar lipase in phospholipid microemulsions
Kornhuber_2004_Fortschr.Neurol.Psychiatr_72_553 [Limited efficacy of cholinesterase inhibitors in Alzheimer's dementia]
Kovrigina_2004_Morfologiia_125_28 [Development of neuromuscular synapse in the skeletal muscle after chemical desympathization]
Kuca_2004_Neurotox.Res_6_565 Reactivation of organophosphate-inhibited acetylcholinesterase by quaternary pyridinium aldoximes
Kumar_2004_Neurol.India_52_307 Memantine: pharmacological properties and clinical uses
Kurz_2004_Alzheimer.Dis.Assoc.Disord_18_123 Disease stage in Alzheimer disease and treatment effects of rivastigmine
Kurz_2004_Curr.Opin.Allergy.Clin.Immunol_4_335 The role of environmental tobacco smoke in genetic susceptibility to asthma
Kurzen_2004_Exp.Dermatol_13 Suppl 4_27 Novel aspects in cutaneous biology of acetylcholine synthesis and acetylcholine receptors
Kwon_2004_J.Wildl.Dis_40_737 Pesticide poisoning events in wild birds in Korea from 1998 to 2002
Lacinski_2004_Cell.Mol.Biol.(Noisy-le-grand)_50_885 Determinants of homocysteine-thiolactonase activity of the paraoxonase-1 (PON1) protein in humans
Lahiri_2004_Curr.Pharm.Des_10_3111 Rationale for the development of cholinesterase inhibitors as anti-Alzheimer agents
Lampen_2004_Biochim.Biophys.Acta_1681_38 Induction of gene expression of xenobiotic metabolism enzymes and ABC-transport proteins by PAH and a reconstituted PAH mixture in human Caco-2 cells
Lampl_2004_Ann.Pharmacother_38_1967 Efficacy of acetylcholinesterase inhibitors in frontotemporal dementia
Langa_2004_JAMA_292_2901 Mixed dementia: emerging concepts and therapeutic implications
Laumonnier_2004_Am.J.Hum.Genet_74_552 X-linked mental retardation and autism are associated with a mutation in the NLGN4 gene, a member of the neuroligin family
Lautt_2004_Proc.West.Pharmacol.Soc_47_30 Pharmaceutical reversal of insulin resistance
Le_2004_Blood_104_2967 Iron chelators with high antiproliferative activity up-regulate the expression of a growth inhibitory and metastasis suppressor gene: a link between iron metabolism and proliferation
Lemaire_2004_Biochem.Pharmacol_68_2347 A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides
Leng_2004_Cancer.Epidemiol.Biomarkers.Prev_13_1631 Effects of genetic polymorphisms of metabolic enzymes on cytokinesis-block micronucleus in peripheral blood lymphocyte among coke-oven workers
Leng_2004_Zhonghua.Lao.Dong.Wei.Sheng.Zhi.Ye.Bing.Za.Zhi_22_245 [Effect of genetic polymorphisms of microsomal epoxide hydrolase on urinary 1-hydroxypyrene levels in coke oven workers]
Leng_2004_Zhonghua.Yu.Fang.Yi.Xue.Za.Zhi_38_94 [A study on the inherited susceptibility of chromosomal damage in peripheral blood lymphocytes among coke oven workers]
Lescic_2004_Biol.Chem_385_1147 Structural characterization of extracellular lipase from Streptomyces rimosus: assignment of disulfide bridge pattern by mass spectrometry
Levario-Carrillo_2004_Exp.Toxicol.Pathol_55_489 Placental morphology of rats prenatally exposed to methyl parathion
Levin_2004_Neurotoxicol.Teratol_26_719 Developmental chlorpyrifos effects on hatchling zebrafish swimming behavior
Lin_2004_Ren.Fail_26_349 Most common intoxication in nephrology ward organophosphate poisoning
Lin_2004_J.Biochem.Mol.Toxicol_18_353 Quantitative structure-activity relationships for the pre-steady state acetylcholinesterase inhibition by carbamates
Lin_2004_J.Enzyme.Inhib.Med.Chem_19_395 Ortho effects in quantitative structure-activity relationships for acetylcholinesterase inhibition by aryl carbamates
Lin_2004_Neurol.Res_26_792 Neuroprotection by D-securinine against neurotoxicity induced by beta-amyloid (25-35)
Lind_2004_Biochim.Biophys.Acta_1702_103 Esterase catalysis of substrate vapour: enzyme activity occurs at very low hydration
Lipczynska-Lojkowska_2004_Neurol.Neurochir.Pol_38_471 [The effect of rivastigmine on cognitive functions and regional cerebral blood flow in Alzheimer's disease and vascular dementia: follow-up for 2 years]
Little_2004_Emerg.Med.Australas_16_456 Consensus statement: risk of nosocomial organophosphate poisoning in emergency departments
Liu_2004_Zhonghua.Nei.Ke.Za.Zhi_43_588 [The clinical features of myasthenia gravis affecting nonskeleton muscles]
Livingston_2004_Int.J.Geriatr.Psychiatry_19_919 The place of memantine in the treatment of Alzheimer's disease: a number needed to treat analysis
Lodovici_2004_Cancer.Epidemiol.Biomarkers.Prev_13_1342 Benzo(a)pyrene diolepoxide (BPDE)-DNA adduct levels in leukocytes of smokers in relation to polymorphism of CYP1A1, GSTM1, GSTP1, GSTT1, and mEH
Lotter_2004_Biotechnol.Lett_26_1191 Correlation between the physicochemical properties of organic solvents and their biocompatibility toward epoxide hydrolase activity in whole-cells of a yeast, Rhodotorula sp
Lotter_2004_Biotechnol.Lett_26_1197 Hydrolytic kinetic resolution of the enantiomers of the structural isomers trans -1-phenylpropene oxide and (2,3-epoxypropyl)benzene by yeast epoxide hydrolase
Loy_2004_Cochrane.Database.Syst.Rev__CD001747 Galantamine for Alzheimer's disease
Lu_2004_Chin.J.Traumatol_7_275 Protective effect of liposome-mediated glial cell line-derived neurotrophic factor gene transfer in vivo on motoneurons following spinal cord injury in rats
Ludin_2004_Praxis.(Bern.1994)_93_1865 [Are there innovations in the treatment of Parkinson's disease?]
Mach_2004_Pharmacol.Biochem.Behav_79_533 Behavioral changes after acetylcholinesterase inhibition with physostigmine in mice
Madill_2004_JAMA_292_2723\; author reply 2723 Chronic fatigue syndrome and the cholinergic hypothesis
Manar_2004_J.Perinatol_24_30 Association of glutathione-S-transferase-P1 (GST-P1) polymorphisms with bronchopulmonary dysplasia
Marcol_2004_Ital.J.Anat.Embryol_109_199 Influence of nerve growth factor upon the injured peripheral nerve in the absence of its distal part
Martins-Afferri_2004_J.Nutr_134_2919 Response to intra- and extracellular lipolytic agents and hormone-sensitive lipase translocation are impaired in adipocytes from rats adapted to a high-protein, carbohydrate-free diet
Masterman_2004_Prim.Care.Companion.J.Clin.Psychiatry_6_126 Role of Cholinesterase Inhibitors in Managing Behavioral Problems in Alzheimer's Disease
Maul_2004_Arch.Environ.Contam.Toxicol_47_253 The effect of sex on avian plasma cholinesterase enzyme activity: a potential source of variation in an avian biomarker endpoint
Maul_2004_Bull.Environ.Contam.Toxicol_73_682 Monitoring exposure of passerines to acephate, dicrotophos, and malathion using cholinesterase reactivation
McKinney_2004_Aquat.Toxicol_69_35 Characterization and profiling of hepatic cytochromes P450 and phase II xenobiotic-metabolizing enzymes in beluga whales (Delphinapterus leucas) from the St. Lawrence River Estuary and the Canadian Arctic
McMillian_2004_Biochem.Pharmacol_68_2249 A gene expression signature for oxidant stress\/reactive metabolites in rat liver
McNamara_2004_Semin.Speech.Lang_25_309 Neuropharmacology of verbal perseveration
Meier-Ruge_2004_Eur.J.Pediatr.Surg_14_392 Diagnosis and therapy of ultrashort Hirschsprung's disease
Mendelsohn_2004_Int.Clin.Psychopharmacol_19_319 Rivastigmine augmentation in the management of chronic schizophrenia with comorbid dementia: an open-label study investigating effects on cognition, behaviour and activities of daily living
Meng_2004_Biosens.Bioelectron_20_1068 A molecularly imprinted catalyst designed by a computational approach in catalysing a transesterification process
Mequid_2004_Pharmazie_59_733 Serum cholinesterase inhibition by omeprazole and lansoprazole
Meyer_2004_N.Engl.J.Med_351_1911 Drug therapy in Alzheimer's disease
Miao_2004_Tissue.Eng_10_807 Megakaryocyte-bone marrow stromal cell aggregates demonstrate increased colony formation and alkaline phosphatase expression in vitro
Mirlesse_2004_Prenat.Diagn_24_498 Alphafoetoprotein and acetylcholinesterase in amniotic fluid as a factor suggesting fetal skin and nerve lesions in a case of congenital varicella syndrome
Miyo_2004_BMC.Genet_5_31 Density-independent population projection trajectories of chromosome-substituted lines resistant and susceptible to organophosphate insecticides in Drosophila melanogaster
Mizutani_2004_J.Med.Chem_47_4818 Efficient method for high-throughput virtual screening based on flexible docking: discovery of novel acetylcholinesterase inhibitors
Moreira_2004_Ecotoxicology_13_619 The 'Coral Bulker' fuel oil spill on the north coast of Portugal: spatial and temporal biomarker responses in Mytilus galloprovincialis
Moretti_2004_Am.J.Alzheimers.Dis.Other.Demen_19_333 Cholinesterase inhibition as a possible therapy for delirium in vascular dementia: a controlled, open 24-month study of 246 patients
Moretti_2004_Drugs.Aging_21_931 Rivastigmine in frontotemporal dementia: an open-label study
Morley_2004_J.Assoc.Res.Otolaryngol_5_391 Transient expression of acetylcholinesterase in the posterior ventral cochlear nucleus of rat brain
Munday_2004_Methods.Enzymol_382_449 Induction of phase II enzymes by aliphatic sulfides derived from garlic and onions: an overview
Munidasa_2004_J.Toxicol.Clin.Toxicol_42_343 Survival pattern in patients with acute organophosphate poisoning receiving intensive care
Munoz_2004_J.Neurosci.Methods_137_133 Microwave-assisted immunostaining: a new approach yields fast and consistent results
Munoz-Muriedas_2004_Curr.Pharm.Des_10_3131 Molecular modelling approaches to the design of acetylcholinesterase inhibitors: new challenges for the treatment of Alzheimer's disease
Nadalin_2004_Liver.Transpl_10_1024 Volumetric and functional recovery of the liver after right hepatectomy for living donation
Nadeau_2004_J.Rehabil.Res.Dev_41_525 Donepezil as an adjuvant to constraint-induced therapy for upper-limb dysfunction after stroke: an exploratory randomized clinical trial
Nakamura_2004_Nihon.Rinsho_62 Suppl 11_368 [Cholinesterase (ChE), acetylcholinesterase (AChE)]
Narahashi_2004_Biol.Pharm.Bull_27_1701 Mechanisms of action of cognitive enhancers on neuroreceptors
Narita_2004_Int.J.Cancer_112_872 Association of lipoprotein lipase gene polymorphism with risk of prostate cancer in a Japanese population
Nawata_2004_Metabolism_53_1395 Increased resting metabolic rate in patients with type 2 diabetes mellitus accompanied by advanced diabetic nephropathy
Newmark_2004_Semin.Neurol_24_185 Nerve agents: pathophysiology and treatment of poisoning
Nishimura_2004_Drug.Metab.Pharmacokinet_19_422 Effects of NO-1886 (Ibrolipim), a lipoprotein lipase-promoting agent, on gene induction of cytochrome P450s, carboxylesterases, and sulfotransferases in primary cultures of human hepatocytes
O'Donovan_2004_Diabetologia_47_2208 Effects of lipase inhibition on gastric emptying of, and on the glycaemic, insulin and cardiovascular responses to, a high-fat\/carbohydrate meal in type 2 diabetes
Oh_2004_Phytomedicine_11_544 Screening of Korean herbal medicines used to improve cognitive function for anti-cholinesterase activity
Ojini_2004_Niger.Postgrad.Med.J_11_193 Clinical manifestations of myasthenia gravis - review of cases seen at the Lagos University Teaching Hospital
Okello_2004_Phytother.Res_18_624 In vitro anti-beta-secretase and dual anti-cholinesterase activities of Camellia sinensis L. (tea) relevant to treatment of dementia
Okereke_2004_Br.J.Clin.Pharmacol_58 Suppl 1_41 Concurrent administration of donepezil HCl and levodopa\/carbidopa in patients with Parkinson's disease: assessment of pharmacokinetic changes and safety following multiple oral doses
Olazaran_2004_Neurology_63_2348 Benefits of cognitive-motor intervention in MCI and mild to moderate Alzheimer disease
Olson_2004_Proteins_57_645 Modeling loop reorganization free energies of acetylcholinesterase: a comparison of explicit and implicit solvent models
Olucha-Bordonau_2004_J.Chem.Neuroanat_28_147 Chemical divisions in the medial geniculate body and surrounding paralaminar nuclei of the rat: quantitative comparison of cell density, NADPH diaphorase, acetyl cholin esterase and basal expression of c-fos
Orgogozo_2004_Curr.Med.Res.Opin_20_1815 Effects of galantamine in patients with mild Alzheimer's disease
Orr_2004_Geriatrics_59_34 Apathy in the older adult. Why you should care
Ortega_2004_Phytomedicine_11_539 Anticholinesterase activity in an alkaloid extract of Huperzia saururus
O'Shaughnessy_2004_J.Appl.Toxicol_24_379 Cultured neuronal networks as environmental biosensors
Ozbal_2004_Assay.Drug.Dev.Technol_2_373 High throughput screening via mass spectrometry: a case study using acetylcholinesterase
Pajoumand_2004_Hum.Exp.Toxicol_23_565 Benefits of magnesium sulfate in the management of acute human poisoning by organophosphorus insecticides
Palacios-Nava_2004_Salud.Publica.Mex_46_286 [Health differences between male and female migrant agricultural workers in Sinaloa, Mexico]
Panda_2004_Neurol.India_52_453 Myasthenic crisis: a retrospective study
Paraoanu_2004_FEBS.Lett_576_161 Mouse acetylcholinesterase interacts in yeast with the extracellular matrix component laminin-1beta
Parikh_2004_Eur.J.Neurosci_20_1545 Rapid assessment of in vivo cholinergic transmission by amperometric detection of changes in extracellular choline levels
Peng_2004_Drug.Metab.Dispos_32_805 Inhibition of murine cytochrome P4501A by tacrine: in vitro studies
Periclou_2004_Ann.Pharmacother_38_1389 Lack of pharmacokinetic or pharmacodynamic interaction between memantine and donepezil
Perneczky_2004_MMW.Fortschr.Med_146 Spec No 2_53 [Current antidementive therapy]
Perrone_2004_Arch.Toxicol_78_589 Embryonic turkey liver: activities of biotransformation enzymes and activation of DNA-reactive carcinogens
Peters_2004_Bioorg.Med.Chem.Lett_14_3575 An aminomethylpyrimidine DPP-IV inhibitor with improved properties
Peters_2004_Bioorg.Med.Chem.Lett_14_3579 Aminomethylpyridines as DPP-IV inhibitors
Petroianu_2004_J.Appl.Toxicol_24_429 Enzyme reactivator treatment in organophosphate exposure: clinical relevance of thiocholinesteratic activity of pralidoxime
Pham_2004_J.Immunol_173_7277 Papillon-Lefevre syndrome: correlating the molecular, cellular, and clinical consequences of cathepsin C\/dipeptidyl peptidase I deficiency in humans
Pick_2004_Int.J.Dev.Neurosci_22_523 Blood-cell-specific acetylcholinesterase splice variations under changing stimuli
Pierantozzi_2004_Clin.Neurophysiol_115_2410 Different TMS patterns of intracortical inhibition in early onset Alzheimer dementia and frontotemporal dementia
Pilgram_2004_Anaesthesist_53_629 [Relaxant awake but still relaxed]
Poet_2004_Neurotoxicol_25_1013 Physiologically based pharmacokinetic\/pharmacodynamic model for the organophosphorus pesticide diazinon
Prange_2004_Proc.Natl.Acad.Sci.U.S.A_101_13915 A balance between excitatory and inhibitory synapses is controlled by PSD-95 and neuroligin
Press_2004_N.Engl.J.Med_351_2547 Parkinson's disease dementia--a first step?
Pritchard_2004_Biosens.Bioelectron_20_765 Sonochemically fabricated enzyme microelectrode arrays for the environmental monitoring of pesticides
Pro_2004_Histol.Histopathol_19_1345 CD26\/dipeptidyl peptidase IV and its role in cancer
Proenca_2004_Forensic.Sci.Int_146 Suppl_S79 Aldicarb poisoning: one case report
Pyun_2004_Bioorg.Med.Chem.Lett_14_91 Investigation of novel fumagillin analogues as angiogenesis inhibitors
Racchi_2004_Pharmacol.Res_50_441 Acetylcholinesterase inhibitors: novel activities of old molecules
Raijmakers_2004_Acta.Obstet.Gynecol.Scand_83_1056 The Tyr113His polymorphism in exon 3 of the microsomal epoxide hydrolase gene is a risk factor for perinatal mortality
Ranaei-Siadat_2004_J.Biochem.Mol.Biol_37_330 Modification of substrate inhibition of synaptosomal acetylcholinesterase by cardiotoxins
Randhawa_2004_Am.Fam.Physician_70_1329 Screening for dementia
Ranhoff_2004_Tidsskr.Nor.Laegeforen_124_3072 [Drug therapy of delirium in the elderly]
Rao_2004_Ecotoxicol.Environ.Saf_59_217 Effects of monocrotophos and its analogs in acetylcholinesterase activity's inhibition and its pattern of recovery on euryhaline fish, Oreochromis mossambicus
Rao_2004_Environ.Res_96_323 Toxicity of azodrin on the morphology and acetylcholinesterase activity of the earthworm Eisenia foetida
Raszewski_2004_Przegl.Lek_61_181 [Use of oximes in the therapy of acute intoxication by organophosphorus compounds]
Raygani_2004_Neurosci.Lett_371_142 Analysis of association between butyrylcholinesterase K variant and apolipoprotein E genotypes in Alzheimer's disease
Recanatini_2004_Curr.Pharm.Des_10_3157 Acetylcholinesterase inhibitors as a starting point towards improved Alzheimer's disease therapeutics
Reetz_2004_Chem.Commun.(Camb)__2750 Liquid poly(ethylene glycol) and supercritical carbon dioxide as a biphasic solvent system for lipase-catalyzed esterification
Renuka_2004_Life.Sci_75_2269 Alterations in the muscarinic M1 and M3 receptor gene expression in the brain stem during pancreatic regeneration and insulin secretion in weanling rats
Reyes_2004_Br.J.Clin.Pharmacol_58 Suppl 1_9 Steady-state pharmacokinetics, pharmacodynamics and tolerability of donepezil hydrochloride in hepatically impaired patients
Rhee_2004_Biol.Pharm.Bull_27_1804 Isolation of the acetylcholinesterase inhibitor ungeremine from Nerine bowdenii by preparative HPLC coupled on-line to a flow assay system
Rispoli_2004_Pharmacol.Biochem.Behav_78_667 Electroencephalographic effects induced by choline pivaloyl esters in scopolamine-treated or nucleus basalis magnocellularis lesioned rats
Roberts_2004_QJM_97_697 Secondary contamination in organophosphate poisoning
Rockwood_2004_Int.J.Geriatr.Psychiatry_19_954 Potential treatment effects of donepezil not detected in Alzheimer's disease clinical trials: a physician survey
Roelants_2004_Anesthesiology_101_439 Epidural neostigmine combined with sufentanil provides balanced and selective analgesia in early labor
Roman_2004_J.Neurol.Sci_226_49 Facts, myths, and controversies in vascular dementia
Rossi_2004_Adv.Mind.Body.Med_20_12 Stress-induced alternative gene splicing in mind-body medicine
Rossini_2004_Bone_35_771 Prevalence and correlates of vertebral fractures in adults with cystic fibrosis
Roy_2004_Bioorg.Med.Chem.Lett_14_1019 Cytochrome P450\/NADPH-dependent formation of trans epoxides from trans-arachidonic acids
Rozengart_2004_Dokl.Biochem.Biophys_397_220 Degree of homogeneity of cholinesterase activity of nervous tissue of squids as a taxonomic trait
Rozengart_2004_Dokl.Biochem.Biophys_399_358 Differences in substrate specificity of the cholinesterase activity of nervous tissue of squids may be used in taxonomy
Rozengart_2004_Dokl.Biochem.Biophys_399_347 Different sensitivity of squid cholinesterases to irreversible organophosphorous inhibitors may be used as a species-specific character in cephalopod taxonomy
Rozengart_2004_Dokl.Biochem.Biophys_398_278 The use of reversible inhibitors of cholinesterases for identification of intraspecific groups of the Comandor squid Berryteuthis magister from different zones of the northwestern area of the Pacific Ocean
Rui_2004_Zhonghua.Yu.Fang.Yi.Xue.Za.Zhi_38_419 [Relationship between acute dipterex poisoning and oxidative stress and free radical damage]
Ruiz_2004_Rev.Clin.Esp_204_511 [Distinguishing pleural transudates and exudates through the quantification of biochemical parameters]
Rumiantseva_2004_Morfologiia_125_40 [Age-dependent changes of morphometric and histochemical characteristics of neurocytes in different ganglia of albino rats]
Rusyniak_2004_Semin.Neurol_24_197 Organophosphate poisoning
Sadananda_2004_J.Biosci_29_189 Acetylcholinesterase in central vocal control nuclei of the zebra finch (Taeniopygia guttata)
Saitoh_2004_Anaesthesia_59_750 Reversal of vecuronium with neostigmine in patients with diabetes mellitus
Salloway_2004_Neurology_63_651 Efficacy of donepezil in mild cognitive impairment: a randomized placebo-controlled trial
Salnikow_2004_Toxicol.Appl.Pharmacol_196_258 Effect of nickel and iron co-exposure on human lung cells
Sambrook_2004_Can.J.Psychiatry_49_417 Canadian Outcomes Study in Dementia: study methods and patient characteristics
Sanchez-Brunete_2004_J.Food.Prot_67_2565 High-performance liquid chromatography multiresidue method for the determination of N-methyl carbamates in fruit and vegetable juices
Sanchez-Hernandez_2004_Environ.Pollut_132_479 Inhibition of plasma butyrylcholinesterase activity in the lizard Gallotia galloti palmae by pesticides: a field study
Sano_2004_Manag.Care.Interface_17_44 Economic effect of cholinesterase inhibitor therapy: implications for managed care
Sarmanova_2004_Eur.J.Hum.Genet_12_848 Breast cancer: role of polymorphisms in biotransformation enzymes
Satar_2004_Mt.Sinai.J.Med_71_405 Ultrastructural changes in rat liver treated with pralidoxime following acute organophosphate poisoning
Satar_2004_Adv.Ther_21_301 Endocrine effects of organophosphate antidotal therapy
Sato_2004_J.Hum.Genet_49_29 Soluble epoxide hydrolase variant (Glu287Arg) modifies plasma total cholesterol and triglyceride phenotype in familial hypercholesterolemia: intrafamilial association study in an eight-generation hyperlipidemic kindred
Saxena_2004_J.Biochem.Mol.Toxicol_18_221 Lead-induced oxidative stress and hematological alterations and their response to combined administration of calcium disodium EDTA with a thiol chelator in rats
Schiere_2004_Eur.J.Anaesthesiol_21_882 An interstitial compartment is necessary to link the pharmacokinetics and pharmacodynamics of mivacurium
Schmidtova_2004_Acta.Medica.(Hradec.Kralove)_47_205 Acetylcholinesterase (AChE)-positive innervation of the guinea-pig spleen
Schmitt_2004_CNS.Drugs_18_827 Combination therapy in Alzheimer's disease: a review of current evidence
Schoenmaker_2004_Lancet.Neurol_3_627 The age gap between patients in clinical studies and in the general population: a pitfall for dementia research
Schrag_2004_J.Neurol_251_795 Psychiatric aspects of Parkinson's disease--an update
Schwemmle_2004_HNO_52_1103 [Dementia-current knowledge and significance for ENT specialists]
Schwierking_2004_ScientificWorldJournal_4_948 Organophosphate nerve agent detection with europium complexes
Serrano_2004_Neurology_63_S31 Fluctuations in cognition and alertness in Parkinson's disease and dementia
Shafeek_2004_Ecotoxicol.Environ.Saf_59_205 Alterations in acetylcholinesterase and electrical activity in the nervous system of cockroach exposed to the neem derivative, azadirachtin
Sharabi_2004_Isr.Med.Assoc.J_6_396 Does acetylcholinesterase inhibition affect catecholamine secretion by adrenomedullary cells?
Sharma_2004_Lancet.Infect.Dis_4_478 India expands mass chemotherapy to eradicate filariasis
Sharma_2004_J.Assoc.Physicians.India_52_387 Evaluation of cholinesterase to differentiate pleural exudates and transudates
Shelton_2004_Neuromuscul.Disord_14_535 'Dropped head sign' in myasthenia gravis
Shimada_2004_Cancer.Sci_95_1 Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and 1B1
Sicras_2004_Rev.Neurol_39_312 [Drug-cholinesterase-inhibitors persistence patterns in treated patients with dementia of Alzheimer type: retrospective comparative analysis of donepezil, rivastigmine and galantamine]
Siegfried_2004_J.Econ.Entomol_97_1726 Monitoring western corn rootworm (Coleoptera: Chrysomelidae) susceptibility to carbaryl and cucurbitacin baits in the areawide management pilot program
Silva_2004_Toxicol.Lett_153_247 Methyl-paraoxon comparative inhibition kinetics for acetylcholinesterases from brain of neotropical fishes
Simard_2004_J.Neuropsychiatry.Clin.Neurosci_16_409 The acetylcholinesterase inhibitors for treatment of cognitive and behavioral symptoms in dementia with Lewy bodies
Simola_2004_Exp.Neurol_189_182 Blockade of adenosine A2A receptors antagonizes parkinsonian tremor in the rat tacrine model by an action on specific striatal regions
Sirot'akova_2004_Acta.Medica.(Hradec.Kralove)_47_201 Butyrylcholinesterase-positive innervation of the spleen in rats
Sivanesan_2004_Biomed.Environ.Sci_17_257 Genotoxicity of pesticide waste contaminated soil and its leachate
Snellman_2004_J.Ind.Microbiol.Biotechnol_31_391 Acinetobacter lipases: molecular biology, biochemical properties and biotechnological potential
Sobow_2004_Psychiatr.Pol_38_321 [The clinical relevance of memantine use]
Sogorb_2004_Rev.Neurol_39_739 [Perspectives in the treatments of poisonings by organophosphorus insecticides and warfare nerve agents]
Song_2004_Biophys.J_87_1558 Continuum diffusion reaction rate calculations of wild-type and mutant mouse acetylcholinesterase: adaptive finite element analysis
Sortino_2004_Neuropharmacol_47_1198 Novel neuronal targets for the acetylcholinesterase inhibitor donepezil
Speare_2004_Org.Biomol.Chem_2_2942 Synthetic 6-aryl-2-hydroxy-6-ketohexa-2,4-dienoic acid substrates for C-C hydrolase BphD: investigation of a general base catalytic mechanism
Spector_2004_Prog.Lipid.Res_43_55 Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function
Srinivas_2004_Indian.J.Exp.Biol_42_214 Hydrolysis of organophosphorus compounds by an esterase isozyme from insecticide resistant pest Helicoverpa armigera
Srivastava_2004_Arch.Biochem.Biophys_427_164 Polymorphisms in human soluble epoxide hydrolase: effects on enzyme activity, enzyme stability, and quaternary structure
Stasiuk_2004_Biochim.Biophys.Acta_1667_215 The effect of merulinic acid on biomembranes
Stocker_2004_Biochimie_86_919 Effect of flavonoids from various Mediterranean plants on enzymatic activity of intestinal carboxylesterase
Stojan_2004_Biochim.Biophys.Acta_1703_53 Rational polynomial equation as an unbiased approach for the kinetic studies of Drosophila melanogaster acetylcholinesterase reaction mechanism
Stovichek_2004_Morfologiia_125_14 [Principles of morphogenesis of the visceral innervation during different stages of human postnatal development]
Straus_2004_JAMA_292_1234 Pharmacotherapy of chronic fatigue syndrome: another gallant attempt
Strong_2004_Am.J.Ind.Med_46_599 Health symptoms and exposure to organophosphate pesticides in farmworkers
Strub_2004_BMC.Biochem_5_9 Mutation of exposed hydrophobic amino acids to arginine to increase protein stability
Stryjer_2004_Hum.Psychopharmacol_19_343 Donepezil augmentation of clozapine monotherapy in schizophrenia patients: a double blind cross-over study
Su_2004_Rapid.Commun.Mass.Spectrom_18_2217 Determination of tributyrin and its metabolite butyrate in Wistar rat plasma samples by gas chromatography\/mass spectrometry
Suehiro_2004_Hepatogastroenterology_51_1776 Preoperative hyaluronic acid measurement to assess the hepatic functional reserve
Sugimoto_2004_Nihon.Yakurigaku.Zasshi_124_163 [Scope and limitations of acetylcholinesterase inhibitors]
Suh_2004_Clin.Ther_26_1608 A prospective, double-blind, community-controlled comparison of three doses of galantamine in the treatment of mild to moderate Alzheimer's disease in a Korean population
Suneetha_2004_Int.J.Lepr.Other.Mycobact.Dis_72_324 Serum butyrylcholinesterase activity in leprosy
Surina_2004_Coll.Antropol_28 Suppl 2_297 Cholinesterase unit establishment and issuing of >>Warning Cards<< for carriers of suxamethonium sensitive serum butyrylcholinesterase variants
Sutherland_2004_J.Med.Chem_47_5541 A comparison of methods for modeling quantitative structure-activity relationships
Sutherland_2004_Clin.Exp.Pharmacol.Physiol_31_817 Enzymatic bioremediation: from enzyme discovery to applications
Suzuki_2004_J.Agric.Food.Chem_52_7407 Purification and characterization of lipase in buckwheat seed
Svedberg_2004_Neuropharmacol_47_558 Effect of subchronic galantamine treatment on neuronal nicotinic and muscarinic receptor subtypes in transgenic mice overexpressing human acetylcholinesterase
Takagi_2004_Nihon.Rinsho_62 Suppl 12_71 [Analysis of lipoprotein lipase activity, immunoreactive mass and gene]
Takamatsu_2004_J.Surg.Res_119_14 Role of leukotrienes on hepatic ischemia\/reperfusion injury in rats
Takaro_2004_Int.J.Occup.Environ.Health_10_256 Glycophorin A is a potential biomarker for the mutagenic effects of pesticides
Talebizadeh_2004_J.Autism.Dev.Disord_34_735 Do known mutations in neuroligin genes (NLGN3 and NLGN4) cause autism?
Tanaka_2004_J.Neurol.Sci_225_135 Prediction of psychiatric response to donepezil in patients with mild to moderate Alzheimer's disease
Tarkowski_2004_Int.J.Occup.Med.Environ.Health_17_325 The lymphocytic cholinergic system and its modulation by organophosphorus pesticides
Taylor_2004_Genet.Med_6_481 Lipoprotein lipase locus and progression of atherosclerosis in coronary-artery bypass grafts
Teixeira_2004_Toxicology_195_231 Occupational exposure to styrene: modulation of cytogenetic damage and levels of urinary metabolites of styrene by polymorphisms in genes CYP2E1, EPHX1, GSTM1, GSTT1 and GSTP1
Tejo_2004_J.Mol.Model_10_358 Structure and dynamics of Candida rugosa lipase: the role of organic solvent
Thompson_2004_Expert.Opin.Drug.Saf_3_425 The benefits and risks associated with cholinesterase inhibitor therapy in Alzheimer's disease
Thum_2004_Circ.Res_94_e1 Mechanistic role of cytochrome P450 monooxygenases in oxidized low-density lipoprotein-induced vascular injury: therapy through LOX-1 receptor antagonism?
Tiemersma_2004_Int.J.Cancer_108_97 Effect of SULT1A1 and NAT2 genetic polymorphism on the association between cigarette smoking and colorectal adenomas
Tien_2004_J.Neurosci.Res_78_259 Increased diisopropylfluorophosphate-induced toxicity in mu-opioid receptor knockout mice
Timur_2004_Artif.Cells.Blood.Substit.Immobil.Biotechnol_32_427 Acetylcholinesterase (AChE) electrodes based on gelatin and chitosan matrices for the pesticide detection
Tobin_2004_Clin.Pharmacol.Ther_76_505 Inhibition of acetylcholinesterase in patients receiving irinotecan (camptothecin-11)
Tripathi_2004_Phytother.Res_18_501 Enzyme inhibition by the molluscicidal agent Punica granatum Linn. bark and Canna indica Linn. root
Tsai_2004_BMC.Pregnancy.Childbirth_4_27 Potential of essential fatty acid deficiency with extremely low fat diet in lipoprotein lipase deficiency during pregnancy: A case report
Tsatsakis_2004_Forensic.Sci.Int_145_195 Progress in pesticide and POPs hair analysis for the assessment of exposure
Tsukada_2004_Nihon.Yakurigaku.Zasshi_124_153 [Pre-clinical evaluation of effects of acetylcholinesterase inhibition on the cerebral cholinergic neuronal system and cognitive function: PET study in conscious monkeys]
Tsuzuki_2004_Biochim.Biophys.Acta_1684_1 Inhibitory effect of lysophosphatidylcholine on pancreatic lipase-mediated hydrolysis in lipid emulsion
Tumiatti_2004_J.Med.Chem_47_6490 Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 3. Effect of replacing the inner polymethylene chain with cyclic moieties
Tung_2004_Mol.Pharmacol_66_794 P2Y2 receptor activation regulates the expression of acetylcholinesterase and acetylcholine receptor genes at vertebrate neuromuscular junctions
Tutor-Crespo_2004_J.Clin.Pharmacol_44_974 Possible induction of cholinesterase in epileptic patients treated with anticonvulsant drugs: relationship with lipoprotein levels
Ukai_2004_Int.Clin.Psychopharmacol_19_355 Treatment of typical Charles Bonnet syndrome with donepezil
Urbain_2004_Planta.Med_70_1011 Xanthones from Gentiana campestris as new acetylcholinesterase inhibitors
Usmani_2004_Chem.Biol.Interact_150_221 In vitro metabolism of carbofuran by human, mouse, and rat cytochrome P450 and interactions with chlorpyrifos, testosterone, and estradiol
Vakurov_2004_Biosens.Bioelectron_20_1118 Acetylcholinesterase-based biosensor electrodes for organophosphate pesticide detection. I. Modification of carbon surface for immobilization of acetylcholinesterase
van den Bliek_2004_Ned.Tijdschr.Geneeskd_148_2149\; author reply 2149 [Successful treatment of three elderly patients suffering from prolonged delirium using the cholinesterase inhibitor rivastigmine]
van der Schalie_2004_J.Appl.Toxicol_24_387 Response characteristics of an aquatic biomonitor used for rapid toxicity detection
Varoqueaux_2004_Eur.J.Cell.Biol_83_449 Neuroligin 2 is exclusively localized to inhibitory synapses
Veselovskii_2004_Biomed.Khim_50_314 [Dual monoaminoxidase and acetylcholinesterase inhibitors as potential agents for treatment of Alzheimer disease]
Vijayakumar_2004_Biotechnol.Lett_26_1323 Lipase catalyzed synthesis of L-alanyl, L-leucyl and L-phenylalanyl esters of D-glucose using unprotected amino acids
Villarroya_2004_Curr.Pharm.Des_10_3177 New classes of AChE inhibitors with additional pharmacological effects of interest for the treatment of Alzheimer's disease
Vincent_2004_Am.J.Med.Genet.B.Neuropsychiatr.Genet_129B_82 Mutation screening of X-chromosomal neuroligin genes: no mutations in 196 autism probands
Vranic_2004_Bosn.J.Basic.Med.Sci_4_25 Sonophoresis-mechanisms and application
Wada_2004_Nihon.Rinsho_62 Suppl 11_402 [Pancreatic lipase]
Wang_2004_Zhongguo.Wei.Zhong.Bing.Ji.Jiu.Yi.Xue_16_743 [Pre-hospital systematic treatment for patients with severe acute organophosphorus pesticide poisoning]
Wheelock_2004_Environ.Toxicol.Chem_23_2699 Development of toxicity identification evaluation procedures for pyrethroid detection using esterase activity
White_2004_J.Med.Entomol_41_1034 An in vitro larval immersion microassay for identifying and characterizing candidate acaricides
Wilson_2004_Environ.Toxicol_19_554 Effects of in vitro exposure to low levels of organotin and carbamate pesticides on human natural killer cell cytotoxic function
Wiltfang_2004_MMW.Fortschr.Med_146_38 [Neurochemical early and differential diagnostics for Alzheimer's disease]
Winblad_2004_Alzheimer.Dis.Assoc.Disord_18 Suppl 1_S2 Long-term treatment of Alzheimer disease: efficacy and safety of acetylcholinesterase inhibitors
Wint_2004_J.Geriatr.Psychiatry.Neurol_17_127 Psychosis in Parkinson's disease
Wong_2004_J.Agric.Food.Chem_52_6361 Multiresidue determination of pesticides in malt beverages by capillary gas chromatography with mass spectrometry and selected ion monitoring
Wood_2004_Clin.Lab_50_455 Establishment of reference intervals for enzyme catalytic activity concentration measurements at 37 degrees C--a practical approach
Woodley_2004_Eur.J.Neurosci_20_1025 Differential activation of glomeruli in the ferret's main olfactory bulb by anal scent gland odours from males and females: an early step in mate identification
Wu_2004_J.Econ.Entomol_97_1689 Seasonal changes of methamidophos susceptibility and biochemical properties in Plutella xylostella (Lepidoptera: Yponomeutidae) and its parasitoid Cotesia plutellae (Hymenoptera: Braconidae)
Xu_2004_J.Physiol_561_657 Histamine innervation and activation of septohippocampal GABAergic neurones: involvement of local ACh release
Xu_2004_Biosens.Bioelectron_20_579 Single-wall carbon nanotube-based voltammetric sensor and biosensor
Yamada_2004_Pharmacol.Biochem.Behav_78_787 Improvement of scopolamine-induced memory impairment by Z-ajoene in the water maze in mice
Yavuz_2004_Hum.Exp.Toxicol_23_323 Cardiotoxicity in rats induced by methidathion and ameliorating effect of vitamins E and C
You_2004_Arch.Environ.Contam.Toxicol_47_148 Evaluation of desulfuration methods for pyrethroid, organophosphate, and organochlorine pesticides in sediment with high sulfur content
You_2004_Arch.Environ.Contam.Toxicol_47_141 A sonication extraction method for the analysis of pyrethroid, organophosphate, and organochlorine pesticides from sediment by gas chromatography with electron-capture detection
Zalom_2004_Bull.Environ.Contam.Toxicol_73_299 Organophosphate dormant spray pest control efficacy, pesticide concentration and toxicity in storm runoff
Zhang_2004_Chin.Med.Sci.J_19_180 Protective effect of tetramethylpyrazine on learning and memory function in D-galactose-lesioned mice
Zhang_2004_Brain.Res.Mol.Brain.Res_131_136 Galantamine blocks cloned Kv2.1, but not Kv1.5 potassium channels
Zhang_2004_Se.Pu_22_154 [Determination of buprofezin, methamidophos, acephate, and triazophos residues in Chinese tea samples by gas chromatography]
Zhao_2004_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_812_183 Biologically active components of Physostigma venenosum
Zhao_2004_Arch.Pharm.Res_27_1048 Determination of the kinetic properties of platycodin D for the inhibition of pancreatic lipase using a 1,2-diglyceride-based colorimetric assay
Zhou_2004_Biomed.Environ.Sci_17_223 Oxidative stress and free radical damage in patients with acute dipterex poisoning
Zhu_2004_J.Biomed.Sci_11_732 Methyl parathion increases neuronal activities in the rat locus coeruleus
Zimmermann_2004_J.Neurochem_90_1489 Acetylcholinesterase inhibitors increase ADAM10 activity by promoting its trafficking in neuroblastoma cell lines
Zurich_2004_Toxicol.Appl.Pharmacol_201_97 Involvement of glial cells in the neurotoxicity of parathion and chlorpyrifos
Brown_2004_J.Biol.Chem_279_42403 Severe hypoalphalipoproteinemia in mice expressing human hepatic lipase deficient in binding to heparan sulfate proteoglycan
Hemingway_2004_Science_303_1984 Parasitology. New ways to control malaria
Hemingway_2004_Insect.Biochem.Mol.Biol_34_653 The molecular basis of insecticide resistance in mosquitoes
Beato_2004_J.Neurosci_24_895 The activation mechanism of alpha1 homomeric glycine receptors
Burzomato_2004_J.Neurosci_24_10924 Single-channel behavior of heteromeric alpha1beta glycine receptors: an attempt to detect a conformational change before the channel opens
Colquhoun_2004_Trends.Neurosci_27_337 Function and structure in glycine receptors and some of their relatives
Groot-Kormelink_2004_J.Gen.Physiol_123_697 Incomplete incorporation of tandem subunits in recombinant neuronal nicotinic receptors
Farley_2004_Learn.Behav_32_277 Chemosensory conditioning in molluscs: II. A critical review
Jin_2004_Learn.Behav_32_257 Chemosensory conditioning in molluscs: I. Failure of contextual conditioning in Hermissenda
Alkondon_2004_Prog.Brain.Res_145_109 The nicotinic acetylcholine receptor subtypes and their function in the hippocampus and cerebral cortex
Almeida_2004_Bioorg.Med.Chem.Lett_14_1879 Sensitivity of neuronal nicotinic acetylcholine receptors to the opiate antagonists naltrexone and naloxone: receptor blockade and up-regulation
Braga_2004_J.Pharmacol.Exp.Ther_311_700 Pb2+ via protein kinase C inhibits nicotinic cholinergic modulation of synaptic transmission in the hippocampus
Wu_2004_J.Neurosci_24_3527 Hypocretin\/orexin innervation and excitation of identified septohippocampal cholinergic neurons
Zaborszky_2004_J.Neurocytol_33_265 Alpha-adrenergic receptor (alpha(2 A )) is colocalized in basal forebrain cholinergic neurons: a light and electron microscopic double immunolabeling study
Chang_2004_Cochrane.Database.Syst.Rev__CD004358 Inhaled anti-cholinergics for prolonged non-specific cough in children
Selbach_2004_Neurosci_127_519 Orexins\/hypocretins cause sharp wave- and theta-related synaptic plasticity in the hippocampus via glutamatergic, gabaergic, noradrenergic, and cholinergic signaling
Ziebell_2004_J.Biol.Chem_279_17640 Identification of binding sites in the nicotinic acetylcholine receptor for [3H]azietomidate, a photoactivatable general anesthetic
Palea_2004_BJU.Int_94_1125 Involvement of 5-hydroxytryptamine (HT)7 receptors in the 5-HT excitatory effects on the rat urinary bladder
Luthi_2004_BMC.Neurosci_5_44 Bi-directional modulation of AMPA receptor unitary conductance by synaptic activity
Sandberg_2004_Neurobiol.Dis_15_143 Scrapie-infected GT1-1 cells show impaired function of voltage-gated N-type calcium channels (Ca(v) 2.2) which is ameliorated by quinacrine treatment
Innocenti_2004_J.Clin.Oncol_22_2010 Pharmacogenetic analysis of interindividual irinotecan (CPT-11) pharmacokinetic (PK) variability: Evidence for a functional variant of ABCC2
Jenabian_2004_J.Clin.Oncol_22_2065 Genetic polymorphisms of CES2 and their functional consequences
Kitagawa_2004_J.Clin.Oncol_22_2009 Genetic polymorphisms of the multidrug resistance-associated protein 2 gene (ABCC2) and Irinotecan toxicity
Calvo_2004_Insect.Mol.Biol_13_73 The transcriptome of adult female Anopheles darlingi salivary glands
Litwack_2004_Mol.Cell.Neurosci_25_263 Identification and characterization of two novel brain-derived immunoglobulin superfamily members with a unique structural organization
Frenkel_2004_Vaccine_22_2505 Generation of anti-beta-amyloid antibodies via phage display technology
Polsky_2004_Nat.Neurosci_7_621 Computational subunits in thin dendrites of pyramidal cells
Yeung_2004_Biochim.Biophys.Acta_1702_67 Structure\/function analyses of human serum paraoxonase (HuPON1) mutants designed from a DFPase-like homology model
Dolinsky_2004_Biochem.J_378_967 Regulation of the enzymes of hepatic microsomal triacylglycerol lipolysis and re-esterification by the glucocorticoid dexamethasone
Gibbons_2004_Biochem.Soc.Trans_32_59 Synthesis and function of hepatic very-low-density lipoprotein
Gilham_2004_Rev.Endocr.Metab.Disord_5_303 The physiological role of triacylglycerol hydrolase in lipid metabolism
Senten_2004_J.Med.Chem_47_2906 Gamma-amino-substituted analogues of 1-[(S)-2,4-diaminobutanoyl]piperidine as highly potent and selective dipeptidyl peptidase II inhibitors
Kavazarakis_2004_Eur.J.Pediatr_163_462 Severe hypertriglyceridaemia in a Greek infant: a clinical, biochemical and genetic study
Otarod_2004_Curr.Atheroscler.Rep_6_335 Lipoprotein lipase and its role in regulation of plasma lipoproteins and cardiac risk
Abifadel_2004_Clin.Genet_65_158 Identification of the first Lebanese mutation in the LPL gene and description of a rapid detection method
Sitter_2004_J.Neurosci.Res_77_762 High-resolution magic angle spinning and 1H magnetic resonance spectroscopy reveal significantly altered neuronal metabolite profiles in CLN1 but not in CLN3
Malvagia_2004_Mol.Genet.Metab_82_48 New mutations in the PPBG gene lead to loss of PPCA protein which affects the level of the beta-galactosidase\/neuraminidase complex and the EBP-receptor
Vono-Toniolo_2004_Arq.Bras.Endocrinol.Metabol_48_70 Thyroglobulin gene mutations and other genetic defects associated with congenital hypothyroidism
Shanado_2004_Biochem.Biophys.Res.Commun_325_1487 Lysophospholipase I identified as a ghrelin deacylation enzyme in rat stomach
Grave_2004_Dis.Aquat.Organ_60_123 Consumption of drugs for sea lice infestations in Norwegian fish farms: methods for assessment of treatment patterns and treatment rate
Ishihara_2004_J.Hum.Genet_49_302 Functional impairment of two novel mutations detected in lipoprotein-associated phospholipase A2 (Lp-PLA2) deficiency patients
Ninio_2004_Hum.Mol.Genet_13_1341 Platelet-activating factor-acetylhydrolase and PAF-receptor gene haplotypes in relation to future cardiovascular event in patients with coronary artery disease
Bisset_2004_Rev.Cubana.Med.Trop_56_61 [Status of resistance to insecticides and resistance mechanisms in larvae from Playa municipality collected during the intensive campaign against Aedes aegypti in Havana City, 2001-2002]
Bullock_2004_Expert.Rev.Neurother_4_153 Galantamine: use in Alzheimer's disease and related disorders
Dhar_2004_J.Environ.Biol_25_359 Influence of the organophosphorus insecticide phosphamidon on lentic water
Hasnip_2004_Food.Addit.Contam_21_1155 Effects of storage time and temperature on the concentration of ethyl carbamate and its precursors in wine
Khalid_2004_J.Steroid.Biochem.Mol.Biol_92_477 Cholinesterase inhibitory and spasmolytic potential of steroidal alkaloids
Li_2004_Gene_336_231 Complete nucleotide sequence and organization of the naphthalene catabolic plasmid pND6-1 from Pseudomonas sp. strain ND6
Mahadevaswami_2004_J.Basic.Clin.Physiol.Pharmacol_15_211 Evaluation of dimethoate toxicity on pregnancy in albino mice
Mou_2004_Zhongguo.Ji.Sheng.Chong.Xue.Yu.Ji.Sheng.Chong.Bing.Za.Zhi_22_280 [Change of lipid, esterase and lipase in mosquito larvae infected with Lagenidium giganteum]
Vickery_2004_Xenobiotica_34_1025 Incorporation of xenobiotic carboxylic acids into lipids by cultured 3T3-L1 adipocytes
Weinbroum_2004_Br.Med.Bull_72_119 Pathophysiological and clinical aspects of combat anticholinesterase poisoning
Bansal_2004_J.Environ.Biol_25_485 Efficacy of different organophosphate and synthetic pyrethroid insecticides to the larvae of malaria vector Anopheles stephensi, Liston
Bartosova_2004_Acta.Medica.(Hradec.Kralove)_47_249 Therapeutic efficacy of different antidotal mixtures against poisoning with GF-agent in mice
Diaz_2004_Rev.Cubana.Med.Trop_56_111 [Determination of glutathione-S-transferase activity in Culex quinquefaciatus strains in Cuba and other Latin American countries]
Eddleston_2004_Clin.Evid__1941 Organophosphorus poisoning (acute)
Farlow_2004_Expert.Rev.Neurother_4_799 Utilizing combination therapy in the treatment of Alzheimer's disease
Geldmacher_2004_Expert.Rev.Neurother_4_5 Donepezil (Aricept) for treatment of Alzheimer's disease and other dementing conditions
Magdalena_2004_Rev.Cubana.Med.Trop_56_54 [Resistance to insecticides in larvae and adults of Aedes aegypti, Havana City: prevalence of A4 esterasa associated with resistance to temephos]
Musial_2004_Acta.Pol.Pharm_61 Suppl_94 Synthesis of novel N-alkyl carbamates of a-substituted amides of g-hydroxybutyric acid as potential acetylcholinesterase inhibitors
Patocka_2004_Acta.Medica.(Hradec.Kralove)_47_215 Acetylcholinesterase and butyrylcholinesterase--important enzymes of human body
Roman_2004_Panminerva.Med_46_207 Vascular dementia. Advances in nosology, diagnosis, treatment and prevention
Sergutina_2004_Zh.Nevrol.Psikhiatr.Im.S.S.Korsakova_104_56 [Influence of L-DOPA on rat brain depending on individual behavioral features]
Silverberg_2004_Expert.Rev.Neurother_4_97 Novel ventriculo-peritoneal shunt in Alzheimer's disease cerebrospinal fluid biomarkers
Wang_2004_J.Insect.Sci_4_23 The effect of the insecticide dichlorvos on esterase activity extracted from the psocids, Liposcelis bostrychophila and L. entomophila
Chandra_2004_J.Environ.Biol_25_239 First ovarian maturity and recovery response in common carp, Cyprinus carpio after exposure to carbofuran
Inestrosa_2004_Curr.Alzheimer.Res_1_249 Acetylcholinesterase (AChE)--amyloid-beta-peptide complexes in Alzheimer's disease. the Wnt signaling pathway
Masuda_2004_Curr.Alzheimer.Res_1_315 Cardiac effect of cholinesterase inhibitors used in Alzheimer's disease--from basic research to bedside
McLoughlin_2004_Chem.Biol_11_735 The role of inhibition in enzyme evolution
Nevermann_2004_Arch.Latinoam.Nutr_54_444 [Pesticide detection in Costarican vegetables based on the inhibition of serum and erythrocytic human cholinesterases]
Parker_2004_Biochem.Cell.Biol_82_694 Signaling in glial development: differentiation migration and axon guidance
Sagiroglu_2004_Artif.Cells.Blood.Substit.Immobil.Biotechnol_32_625 Preparation and properties of lipases immobilized on different supports
Tireli_2004_Acta.Myol_23_140 Myasthenia gravis: how to treat?
Venema_2004_Dev.Biol_275_301 Transient apical polarization of Gliotactin and Coracle is required for parallel alignment of wing hairs in Drosophila
Wang_2004_J.Econ.Entomol_97_661 Enzymatic chlorophyll degradation in wheat near-isogenic lines elicited by cereal aphid (Homoptera: Aphididae) feeding
Yang_2004_J.Chem.Ecol_30_1057 Humic substances affect the activity of chlorophyllase
Yang_2004_Sheng.Wu.Gong.Cheng.Xue.Bao_20_284 [Study on the repeated batch fermentation of lipase by immobilized Rhizopus]
Colubri_2004_J.Biomol.Struct.Dyn_21_625 Prediction of protein structure by simulating coarse-grained folding pathways: a preliminary report
Ikeda_2004_J.Biosci.Bioeng_98_366 Production of recombinant human lysosomal acid lipase in Schizosaccharomyces pombe: development of a fed-batch fermentation and purification process
Kojima_2004_J.Biosci.Bioeng_98_420 Efficient production of fatty acid methyl ester from waste activated bleaching earth using diesel oil as organic solvent
Merdes_2004_EMBO.J_23_4082 Interference of human and Drosophila APP and APP-like proteins with PNS development in Drosophila
Rendon_2004_Arch.Environ.Health_59_418 Effect of pesticide exposure on acetylcholinesterase activity in subsistence farmers from Campeche, Mexico
Shao_2004_Wei.Sheng.Wu.Xue.Bao_44_789 [Study on low-temperature alkaline lipase from Bohaisea-9145]
Truman_2004_Development_131_5167 Developmental architecture of adult-specific lineages in the ventral CNS of Drosophila
Zhukovskii_2004_Ukr.Biokhim.Zh.(1999)_76_151 [Comparative study of enzymatic activity of cholinesterases of different origin in thionaphthylacetate hydrolysis reactions]
Arciniegas_2004_Phys.Med.Rehabil.Clin.N.Am_15_177 Applications of the P50 evoked response to the evaluation of cognitive impairments after traumatic brain injury
Bentley_2004_Neuron_41_969 Effects of cholinergic enhancement on visual stimulation, spatial attention, and spatial working memory
Brown_2004_Am.J.Ther_11_144 Anticholinergic syndrome after anesthesia: a case report and review
Chang_2004_Hippocampus_14_170 Impaired and spared cholinergic functions in the hippocampus after lesions of the medial septum\/vertical limb of the diagonal band with 192 IgG-saporin
Cobb_2004_Bioelectromagnetics_25_49 Radial arm maze performance of rats following repeated low level microwave radiation exposure
Gabel_2004_Anaesthesist_53_53 [Hypotensive cardio-circulatory failure and metabolic acidosis after suicidal intoxication with trimipramine and quetiapine. Case report and background]
Gonzalez-Coloma_2004_J.Chem.Ecol_30_1393 Structural diversity and defensive properties of norditerpenoid alkaloids
Gooz_2004_Life.Sci_74_2111 Endogenous ouabain-like factor (OLF) secretion is modulated by nicotinic mechanisms in rat adrenocortical cells
Hirose_2004_J.Psychopharmacol_18_375 Mechanism of action of aripiprazole predicts clinical efficacy and a favourable side-effect profile
Huang_2004_J.Am.Chem.Soc_126_14043 Asymmetric synthesis of pyrrolidinoindolines. Application for the practical total synthesis of (-)-phenserine
Kranke_2004_Anesth.Analg_99_718 Single-dose parenteral pharmacological interventions for the prevention of postoperative shivering: a quantitative systematic review of randomized controlled trials
Kulka_2004_Anesth.Analg_99_1376 Suspected central anticholinergic syndrome in a 6-week-old infant
Levi_2004_J.Neurophysiol_91_336 Dual sensory-motor function for a molluskan statocyst network
Lima-Catelani_2004_Biochem.Genet_42_69 Variation of genetic expression during development, revealed by esterase patterns in Aedes aegypti (Diptera, Culicidae)
Ma_2004_Eur.J.Pharmacol_487_205 Muscarinic receptors mediating contraction of female mouse urinary bladder: effects of oestrogen
Mondaca_2004_Pharmacol.Biochem.Behav_77_275 Involvement of melatonin metabolites in the long-term inhibitory effect of the hormone on rat spinal nociceptive transmission
Munday_2004_Toxicon_44_173 Acute toxicity of gymnodimine to mice
Myhrer_2004_Eur.J.Pharmacol_483_271 Cognitive side effects in rats caused by pharmacological agents used to prevent soman-induced lethality
Myhrer_2004_Toxicol.Appl.Pharmacol_196_327 Protection against soman-induced seizures in rats: relationship among doses of prophylactics, soman, and adjuncts
Nagura_2004_Nihon.Rinsho_62 Suppl_76 [Drugs for the treatment of Alzheimer's disease]
Ogawa_2004_Cerebellum_3_107 Pharmacological treatments of cerebellar ataxia
Palma_2004_Neurosci.Lett_368_112 The role of nitrinergic connections in central cardiovascular responses mediated by physostigmine infused into posterior hypothalamus
Park_2004_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_139_303 Cardiac responses of Pacific oyster Crassostrea gigas to agents modulating cholinergic function
Patel_2004_J.Emerg.Med_26_89 Prevalence of autonomic signs and symptoms in antimuscarinic drug poisonings
Patil_2004_J.Pharm.Pharmacol_56_1045 Parameters of drug antagonism: re-examination of two modes of functional competitive drug antagonism on intraocular muscles
Paulikova_2004_Ceska.Slov.Farm_53_85 [Catalytic activity of butyrylcholinesterase in biodegradation of organic ammonium salts in vitro]
Potier_2004_Brain.Res_997_194 Modulation of muscarinic facilitation of epileptiform discharges in immature rat neocortex
Rhodes_2004_Brain.Res.Bull_64_205 Rat estrous cycle influences the sexual diergism of HPA axis stimulation by nicotine
Richardson_2004_J.Emerg.Med_26_463 A picturesque reversal of antimuscarinic delirium
Rizzi_2004_Resuscitation_61_101 Post resuscitation central anticholinergic syndrome
Rodrigues_2004_J.Appl.Physiol.(1985)_97_333 Intracerebroventricular physostigmine facilitates heat loss mechanisms in running rats
Rogers_2004_Learn.Mem_11_102 Cholinergic modulation of the hippocampus during encoding and retrieval of tone\/shock-induced fear conditioning
Rygnestad_2004_Tidsskr.Nor.Laegeforen_124_2736 [Acute deliberate self-poisonings in the area of Trondheim, 1978-2002]
Santucci_2004_Pharmacol.Biochem.Behav_77_59 p-Chloroamphetamine blocks physostigmine-induced memory enhancement in rats with unilateral nucleus basalis lesions
Tammenmaa_2004_Prog.Neuropsychopharmacol.Biol.Psychiatry_28_1099 Systematic review of cholinergic drugs for neuroleptic-induced tardive dyskinesia: a meta-analysis of randomized controlled trials
Tuovinen_2004_Drug.Chem.Toxicol_27_69 Function of plasma and microsomal enzymes in soman toxicity
Urbanska-Rys_2004_Leuk.Lymphoma_45_1913 Multiple myeloma in a patient with systemic lupus erythematosus, myasthenia gravis and non-familial diffuse palmoplantar keratoderma
Vorobyov_2004_Int.J.Radiat.Biol_80_691 Repeated exposure to low-level extremely low frequency-modulated microwaves affects baseline and scopolamine-modified electroencephalograms in freely moving rats
Wang_2004_Biomaterials_25_3275 Preparation, characterization, and in vitro evaluation of physostigmine-loaded poly(ortho ester) and poly(ortho ester)\/poly(D,L-lactide-co-glycolide) blend microspheres fabricated by spray drying
Cummings_2004_Rev.Neurol.Dis_1_60 Treatment of Alzheimer's disease: current and future therapeutic approaches
Kovalev_2004_Ukr.Biokhim.Zh.(1999)_76_39 [Substrate specificity of brain cholinesterase activity of evolutionary old species of fishes]
Okazaki_2004_DNA.Res_11_127 Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries
Woodruff-Pak_2004_Neurobiol.Aging_25_807 Nefiracetam and physostigmine: separate and combined effects on learning in older rabbits
Hughes_2004_Consult.Pharm_19_713 Gastrointestinal adverse events in a general population sample of nursing home residents taking cholinesterase inhibitors
London_2004_Arch.Environ.Health_59_575 Guillain-Barre syndrome in a rural farming district in South Africa: a possible relationship to environmental organophosphate exposure
Siritunga_2004_Plant.Mol.Biol_56_661 Engineering cyanogen synthesis and turnover in cassava (Manihot esculenta)
Slattum_2004_Consult.Pharm_19_352 Caregiver burden in Alzheimer's disease
Stephens_2004_Arch.Environ.Health_59_566 Neuropsychological effects of long-term low-level organophosphate exposure in orchard sprayers in England
Xu_2004_Appl.Microbiol.Biotechnol_66_27 Enzymatic enantioselective transcyanation of silicon-containing aliphatic ketone with (S)-hydroxynitrile lyase from Manihot esculenta
Yebakima_2004_J.Med.Entomol_41_718 Evolution of resistance under insecticide selection pressure in Culex pipiens quinquefasciatus (Diptera, Culicidae) from Martinique
Berger_2004_Neurobiol.Dis_17_290 Expression analysis of the N-Myc downstream-regulated gene 1 indicates that myelinating Schwann cells are the primary disease target in hereditary motor and sensory neuropathy-Lom
Caux_2004_Am.J.Med.Genet.A_129A_214 CGI-58\/ABHD5 gene is mutated in Dorfman-Chanarin syndrome
Davey_2004_Phytochemistry_65_2197 Effects of elevated CO2 on the vasculature and phenolic secondary metabolism of Plantago maritima
Gutnisky_2004_J.Clin.Endocrinol.Metab_89_646 Two distinct compound heterozygous constellations (R277X\/IVS34-1G>C and R277X\/R1511X) in the thyroglobulin (TG) gene in affected individuals of a Brazilian kindred with congenital goiter and defective TG synthesis
Haupt_2004_MMW.Fortschr.Med_146 Suppl 2_51 [Outpatient treatment of patients suffering from Alzheimer dementia. Two exploratory studies on the characteristics of therapy in medical practice]
Isaacs_2004_J.Clin.Endocrinol.Metab_89_3858 The -514 C->T hepatic lipase promoter region polymorphism and plasma lipids: a meta-analysis
Kwon_2004_Anal.Chem_76_5713 Antibody arrays prepared by cutinase-mediated immobilization on self-assembled monolayers
Murphy_2004_Langmuir_20_1026 Substrates for cell adhesion prepared via active site-directed immobilization of a protein domain
Srinivasan_2004_J.Pediatr_144_662 Steatohepatitis and unsuspected micronodular cirrhosis in Dorfman-Chanarin syndrome with documented ABHD5 mutation
Todorova_2004_J.Clin.Endocrinol.Metab_89_2019 The G-250A promoter polymorphism of the hepatic lipase gene predicts the conversion from impaired glucose tolerance to type 2 diabetes mellitus: the Finnish Diabetes Prevention Study
Bruhlmann_2004_Chem.Biodivers_1_819 Screening of non-alkaloidal natural compounds as acetylcholinesterase inhibitors
Riaz_2004_Chem.Biodivers_1_1289 Cholinesterase-inhibiting withanolides from Ajuga bracteosa
Kang_2004_Reprod.Fertil.Dev_16_763 Gene expression analysis of the pro-oestrous-stage rat uterus reveals neuroligin 2 as a novel steroid-regulated gene
Siritunga_2004_Plant.Biotechnol.J_2_37 Over-expression of hydroxynitrile lyase in transgenic cassava roots accelerates cyanogenesis and food detoxification
Zamocky_2004_Gene_338_1 Ancestral gene fusion in cellobiose dehydrogenases reflects a specific evolution of GMC oxidoreductases in fungi
Kim_2004_Mol.Pharm_1_434 Structure and specificity of a human valacyclovir activating enzyme: a homology model of BPHL
Matthee_2004_Syst.Biol_53_433 A molecular supermatrix of the rabbits and hares (Leporidae) allows for the identification of five intercontinental exchanges during the Miocene
Tomer_2004_Trends.Mol.Med_10_306 The thyroglobulin gene as the first thyroid-specific susceptibility gene for autoimmune thyroid disease
Atchison_2004_Toxicol.Mech.Methods_14_183 Development of a Guinea pig model for low-dose, long-term exposure to organophosphorus nerve agents
Barch_2004_Psychopharmacology.(Berl)_174_126 Pharmacological manipulation of human working memory
Bourguet_2004_Evolution_58_128 Fitness costs of insecticide resistance in natural breeding sites of the mosquito Culex pipiens
Brasaemle_2004_J.Biol.Chem_279_46835 Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes
Gosselin_2004_Toxicol.Mech.Methods_15_33 Toxicokinetic modeling of parathion and its metabolites in humans for the determination of biological reference values
Liu_2004_J.Biol.Chem_279_3787 Chinese hamster ovary K2 cell lipid droplets appear to be metabolic organelles involved in membrane traffic
Murray_2004_Biochem.J_384_477 Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3
Steller_2004_Biochemistry_43_11331 Initiation of surfactin biosynthesis and the role of the SrfD-thioesterase protein
Kethidi_2004_J.Biol.Chem_279_19634 Identification and characterization of a juvenile hormone (JH) response region in the JH esterase gene from the spruce budworm, Choristoneura fumiferana
Min_2004_J.Insect.Physiol_50_531 Increased juvenile hormone levels after long-duration flight in the grasshopper, Melanoplus sanguinipes
Jaeger_2004_Curr.Opin.Biotechnol_15_305 Enantioselective biocatalysis optimized by directed evolution
Lopez-Miranda_2004_J.Clin.Endocrinol.Metab_89_4721 The influence of lipoprotein lipase gene variation on postprandial lipoprotein metabolism
Streit_2004_Curr.Opin.Biotechnol_15_285 Prospecting for biocatalysts and drugs in the genomes of non-cultured microorganisms
Yang_2004_Hum.Genet_115_8 Lipoprotein lipase gene is in linkage with blood pressure phenotypes in Chinese pedigrees
Kreuger_2004_Dev.Cell_7_503 Opposing activities of Dally-like glypican at high and low levels of Wingless morphogen activity
Moralev_2004_Zh.Evol.Biokhim.Fiziol_40_3 [Comparative sensitivity of different Cholinesterases of different origin to its inhibitors]
Nakanishi_2004_Oncol.Rep_12_1273 Loss of imprinting of PEG1\/MEST in lung cancer cell lines
Oesch_2004_Nonlinearity.Biol.Toxicol.Med_2_21 Detoxication strategy of epoxide hydrolase-the basis for a novel threshold for definable genotoxic carcinogens
Shi_2004_Genesis_39_65 Loss-of-imprinting of Peg1 in mouse interspecies hybrids is correlated with altered growth
Sviderskii_2004_Dokl.Biochem.Biophys_396_193 Study of molecular-biochemical mechanism of action of iodine-containing extract from laminaria (Laminaria saccharina)
Tyson_2004_Nature_428_37 Community structure and metabolism through reconstruction of microbial genomes from the environment
Danks_2004_Methods.Mol.Med_90_247 Enzyme-prodrug systems: carboxylesterase\/CPT-11
Stinear_2004_Proc.Natl.Acad.Sci.U.S.A_101_1345 Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans
Wierdl_2004_Biochemistry_43_1874 Molecular modeling of CPT-11 metabolism by carboxylesterases (CEs): use of pnb CE as a model
Yoon_2004_Mol.Cancer.Ther_3_903 Characterization of inhibitors of specific carboxylesterases: development of carboxylesterase inhibitors for translational application
Zhang_2004_Biochem.Biophys.Res.Commun_325_414 Homology modeling and S(N)2 displacement reaction of fluoroacetate dehalogenase from Burkholderia sp. FA1
Akoh_2004_Prog.Lipid.Res_43_534 GDSL family of serine esterases\/lipases
Foresti_2004_Biomacromolecules_5_2366 Computational approach to solvent-free synthesis of ethyl oleate using Candida rugosa and Candida antarctica B Lipases. I. Interfacial activation and substrate (ethanol, oleic acid) adsorption
Ishida_2004_Genomics_83_24 Molecular cloning of nonsecreted endothelial cell-derived lipase isoforms
Jutila_2004_Biochim.Biophys.Acta_1702_181 Fluorescence spectroscopic characterization of Humicola lanuginosa lipase dissolved in its substrate
Lee_2004_Environ.Toxicol.Chem_23_1 Microbial transformation of pyrethroid insecticides in aqueous and sediment phases
Haitina_2004_Biochem.J_380_475 Cloning, tissue distribution, pharmacology and three-dimensional modelling of melanocortin receptors 4 and 5 in rainbow trout suggest close evolutionary relationship of these subtypes
Dabouras_2004_Neurosci.Lett_368_68 Exogenous application of glucose induces aging in rat cerebral oligodendrocytes as revealed by alteration in telomere length
Rothermel_2004_Gene.Expr.Patterns_4_59 Spatial and temporal expression patterns of GDNF family receptor alpha4 in the developing chicken retina
Diekmann_2004_Aquat.Toxicol_68_27 On the relevance of genotoxicity for fish populations II: genotoxic effects in zebrafish (Danio rerio) exposed to 4-nitroquinoline-1-oxide in a complete life-cycle test
Luttge_2004_Ann.Bot_93_629 Ecophysiology of Crassulacean Acid Metabolism (CAM)
Peichl_2004_Eur.J.Neurosci_19_1545 Unusual cone and rod properties in subterranean African mole-rats (Rodentia, Bathyergidae)
Ogino_2004_J.Mol.Microbiol.Biotechnol_7_212 Cloning, expression, and characterization of a lipolytic enzyme gene (lip8) from Pseudomonas aeruginosa LST-03
Crepin_2004_Appl.Microbiol.Biotechnol_63_647 Functional classification of the microbial feruloyl esterases
Fernandez-Chacon_2004_Neuron_42_237 The synaptic vesicle protein CSP alpha prevents presynaptic degeneration
Nishimune_2004_Nature_432_580 A synaptic laminin-calcium channel interaction organizes active zones in motor nerve terminals
Jikumaru_2004_Biosci.Biotechnol.Biochem_68_1461 Preparation and biological activity of molecular probes to identify and analyze jasmonic acid-binding proteins
Klichkhanov_2004_Bull.Exp.Biol.Med_138_47 Effect of hypothermia on kinetic characteristics of acetylcholine esterase in rat erythrocyte membranes
Rosenbaum_2004_J.Gen.Physiol_123_295 State-dependent block of CNG channels by dequalinium
Simard_2004_FASEB.J_18_998 Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microglia
Simard_2004_Neuroreport_15_2305 Role of inflammation in the neurobiology of stem cells
London_2004_Nat.Neurosci_7_904 Conducting synaptic music in dendrites
Roth_2004_J.Neurophysiol_91_1941 Rebuilding dendritic democracy. Focus on equalization of synaptic efficacy by activity- and timing-dependent synaptic plasticity
Schmitz_2004_Neuroimage_22_941 Metacognitive evaluation, self-relevance, and the right prefrontal cortex
Chakkalakal_2004_Hum.Mol.Genet_13_379 Stimulation of calcineurin signaling attenuates the dystrophic pathology in mdx mice
Goldberg_2004_J.Neurosci_24_6003 Spike synchronization in the cortex\/basal-ganglia networks of Parkinsonian primates reflects global dynamics of the local field potentials
Goldberg_2004_Neuron_42_489 Patterns of ongoing activity and the functional architecture of the primary visual cortex
Kuperstein_2004_J.Neurochem_91_965 Amyloid Abeta1-40 preconditions non-apoptotic signals in vivo and protects fetal rat brain from intrauterine ischemic stress
Lookene_2004_J.Biol.Chem_279_49964 Rapid subunit exchange in dimeric lipoprotein lipase and properties of the inactive monomer
de Oliveira_2004_Appl.Biochem.Biotechnol_113-116_771 Optimization of enzymatic production of biodiesel from castor oil in organic solvent medium
Takahashi_2004_Macromol.Biosci_4_346 Lipase-catalyzed transformation of poly(lactic acid) into cyclic oligomers
Weber_2004_Appl.Microbiol.Biotechnol_64_800 Mono-thioesters and di-thioesters by lipase-catalyzed reactions of alpha,omega-alkanedithiols with palmitic acid or its methyl ester
Weber_2004_J.Agric.Food.Chem_52_5347 Solvent-free lipase-catalyzed preparation of diacylglycerols
Mandrich_2004_J.Mol.Biol_335_357 Analysis of thermal adaptation in the HSL enzyme family
Park_2004_J.Ind.Microbiol.Biotechnol_31_189 Heterologous gene expression in Thermus thermophilus: beta-galactosidase, dibenzothiophene monooxygenase, PNB carboxy esterase, 2-aminobiphenyl-2,3-diol dioxygenase, and chloramphenicol acetyl transferase
Grandval_2004_Pancreatology_4_495 Critical evaluation of a specific ELISA and two enzymatic assays of pancreatic lipases in human sera
Peeters_2004_Biomacromolecules_5_1862 Cascade synthesis of chiral block copolymers combining lipase catalyzed ring opening polymerization and atom transfer radical polymerization
Sivalingam_2004_Biomacromolecules_5_603 Modeling of lipase catalyzed ring-opening polymerization of epsilon-caprolactone
Gustavsson_2004_Biomacromolecules_5_106 Polyester coating of cellulose fiber surfaces catalyzed by a cellulose-binding module-Candida antarctica lipase B fusion protein
Mesulam_2004_Prog.Brain.Res_145_67 The cholinergic innervation of the human cerebral cortex
Shayman_2004_Glycoconj.J_20_25 A turn in the road: How studies on the pharmacology of glucosylceramide synthase inhibitors led to the identification of a lysosomal phospholipase A2 with ceramide transacylase activity
Xiong_2004_J.Org.Chem_69_8451 Reaction pathways and free energy barriers for alkaline hydrolysis of insecticide 2-trimethylammonioethyl methylphosphonofluoridate and related organophosphorus compounds: electrostatic and steric effects
Jazayeri_2004_Pestic.Biochem.Physiol_80_1 Biochemical studies on sheep body louse Bovicola ovis (Schrank) (Phthiraptera: Trichodectidae): comparison of pyrethroid and organophosphate resistant and susceptible strains
Anderson_2004_Pestic.Biochem.Physiol_80_54 Synergistic and antagonistic effects of atrazine on the toxicity of organophosphorodithioate and organophosphorothioate insecticides to Chironomus tentans (Diptera: Chironomidae)
Ma_2004_Pestic.Biochem.Physiol_78_67 Comparative studies of acetylcholinesterases purified from two field populations of the oriental migratory locust (Locusta migratoria manilensis): implications of insecticide resistance
Papp_2004_Pestic.Biochem.Physiol_79_94 Comparison of the effect of subacute organophosphate exposure on the cortical and peripheral evoked activity in rats
Suresh_2004_Bioresour.Technol_95_327 Production of biodegradable plastics from activated sludge generated from a food processing industrial wastewater treatment plant
Menendez_2004_Oncogene_23_4945 Inhibition of tumor-associated fatty acid synthase activity antagonizes estradiol- and tamoxifen-induced agonist transactivation of estrogen receptor (ER) in human endometrial adenocarcinoma cells
Broedl_2004_Trends.Cardiovasc.Med_14_202 Endothelial lipase: a modulator of lipoprotein metabolism upregulated by inflammation
Berticat_2004_Genet.Res_83_189 Insecticide resistance genes confer a predation cost on mosquitoes, Culex pipiens
Mei_2004_Biomaterials_25_4195 Biocompatibility of sorbitol-containing polyesters. Part I: Synthesis, surface analysis and cell response in vitro
Tansey_2004_IUBMB.Life_56_379 The central role of perilipin a in lipid metabolism and adipocyte lipolysis
Mateo_2004_Plant.Physiol_136_2818 LESION SIMULATING DISEASE 1 is required for acclimation to conditions that promote excess excitation energy
Song_2004_Plant._40_200 A key role for ALD1 in activation of local and systemic defenses in Arabidopsis