Year

Tree Display

AceDB Schema

XML Display

Feedback

Year Report for: 2012

Abbott_2012_J.Physiol_590_2897C1 neurons excite locus coeruleus and A5 noradrenergic neurons along with sympathetic outflow in rats
Abdallah_2012_J.Bacteriol_194_3282Complete genome sequence of Mycobacterium xenopi type strain RIVM700367
Abdallah_2012_J.Bacteriol_194_3284Complete genome sequence of Mycobacterium phlei type strain RIVM601174
Abdel Moneim_2012_Biol.Trace.Elem.Res_148_363Flaxseed oil as a neuroprotective agent on lead acetate-induced monoamineric alterations and neurotoxicity in rats
Abdel-Salam_2012_J.Basic.Clin.Physiol.Pharmacol_23_61The effect of gabapentin on oxidative stress in a model of toxic demyelination in rat brain
Abdillahi_2012_J.Ethnopharmacol_139_728Mutagenicity, antimutagenicity and cytotoxicity evaluation of South African Podocarpus species
Abdollahi_2012_Toxicol.Appl.Pharmacol_258_309A comprehensive review on experimental and clinical findings in intermediate syndrome caused by organophosphate poisoning
Abdul Rahman_2012_Protein.Sci_21_1210Unlocking the mystery behind the activation phenomenon of T1 lipase: a molecular dynamics simulations approach
Abramochkin_2012_J.Comp.Physiol.B_182_101Effects of acetylcholinesterase inhibitor paraoxon denote the possibility of non-quantal acetylcholine release in myocardium of different vertebrates
Abramochkin_2012_Life.Sci_91_1023Both neuronal and non-neuronal acetylcholine take part in non-quantal acetylcholine release in the rat atrium
Abu-Taweel_2012_Indian.J.Exp.Biol_50_696Effects of perinatal exposure of lithium on neuro-behaviour of developing mice offspring
Achatz_2012_Front.Zool_9_27The nervous system of Isodiametra pulchra (Acoela) with a discussion on the neuroanatomy of the Xenacoelomorpha and its evolutionary implications
Acheampong_2012_Biochem.Mol.Biol.Educ_40_144Acetylcholinesterase: substrate traffic and inhibition
Acker_2012_Chemosphere_89_602Chlorpyrifos acute exposure induces hyperglycemia and hyperlipidemia in rats
Adefegha_2012_J.Basic.Clin.Physiol.Pharmacol_23_153Acetylcholinesterase (AChE) inhibitory activity, antioxidant properties and phenolic composition of two Aframomum species
Adekanmi_2012_J.Ethnopharmacol_143_572Cytotoxicity and acetylcholinesterase inhibitory activity of an isolated crinine alkaloid from Boophane disticha (Amaryllidaceae)
Ademosun_2012_J.Med.Food_15_428Inhibition of acetylcholinesterase activity and Fe2+-induced lipid peroxidation in rat brain in vitro by some citrus fruit juices
Adeniyi_2012_Glob.J.Health.Sci_4_118A comparative study of the lateral geniculate body of rat (Rattus norvegicus), bat (Eidolon helvum) and pangolin (Manis tricuspis)
Adeyo_2012_J.Intern.Med_272_528Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 and the intravascular processing of triglyceride-rich lipoproteins
Adhami_2012_J.Ethnopharmacol_139_142Catechol alkenyls from Semecarpus anacardium: acetylcholinesterase inhibition and binding mode predictions
Adibekian_2012_J.Am.Chem.Soc_134_10345Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes
Adler-Abramovich_2012_Nat.Chem.Biol_8_701Phenylalanine assembly into toxic fibrils suggests amyloid etiology in phenylketonuria
Afriat-Jurnou_2012_Biochemistry_51_6047Reconstructing a missing link in the evolution of a recently diverged phosphotriesterase by active-site loop remodeling
Agarwal_2012_Proc.Natl.Acad.Sci.U.S.A_109_17406Structure of the enzyme-acyl carrier protein (ACP) substrate gatekeeper complex required for biotin synthesis
Aggarwal_2012_Eur.J.Med.Genet_55_173Novel nonsense mutation of ABHD5 in Dorfman-Chanarin syndrome with unusual findings: a challenge for genotype-phenotype correlation.
Aghili_2012_Neuropeptides_46_367Polymorphisms in dipeptidyl peptidase IV gene are associated with the risk of myocardial infarction in patients with atherosclerosis
Agrawal_2012_Comb.Chem.High.Throughput.Screen_15_849Ligand-based pharmacophore detection, screening of potential gliptins and docking studies to get effective antidiabetic agents
Aguilera_2012_Ecotoxicology_21_2103Pollution biomarkers in the spiny lizard (Sceloporus spp.) from two suburban populations of Monterrey, Mexico
Ahmad_2012_Protein.Sci_21_433Probing protein stability and proteolytic resistance by loop scanning: a comprehensive mutational analysis
Ahmed_2012_Bull.Environ.Contam.Toxicol_89_229Toxicological effect of herbicides (diuron and bentazon) on snake venom and electric eel acetylcholinesterase
Ahmed_2012_J.Bacteriol_194_3922Comparative genomic analyses of 17 clinical isolates of Gardnerella vaginalis provide evidence of multiple genetically isolated clades consistent with subspeciation into genovars
Ahmed_2012_PLoS.ONE_7_E48228Genomic comparison of Escherichia coli O104:H4 isolates from 2009 and 2011 reveals plasmid, and prophage heterogeneity, including shiga toxin encoding phage stx2
Ahmed_2012_Toxicol.Ind.Health_30_415Toxicological effect of N, N, N', N'-tetramethylethylene on rat brain acetylcholinesterase
Ahn_2012_Bioorg.Med.Chem.Lett_22_2760A new pancreatic lipase inhibitor from Broussonetia kanzinoki
Ahn_2012_Int.J.Food.Sci.Nutr_63_187Preparation and biological evaluation of enzyme-assisted extracts from edible seaweed (Enteromorpha prolifera) as antioxidant, anti-acetylcholinesterase and inhibition of lipopolysaccharide-induced nitric oxide production in murine macrophages
Ahuja_2012_J.Am.Chem.Soc_134_8212Illuminating the diversity of aromatic polyketide synthases in Aspergillus nidulans
Aicher_2012_Obesity.(Silver.Spring)_20_2057Diet-induced weight loss in overweight or obese women and changes in high-density lipoprotein levels and function
Aisen_2012_Cold.Spring.Harb.Perspect.Med_2_a006395Symptomatic and nonamyloid/tau based pharmacologic treatment for Alzheimer disease
Akbar_2012_Pestic.Biochem.Physiol_103_31Methylparathion- and carbofuran-induced mitochondrial dysfunction and oxidative stress in Helicoverpa armigera (Noctuidae: Lepidoptera)
Akkad_2012_J.AOAC.Int_95_1371Determination of organophosphorus and carbamate insecticides in fresh fruits and vegetables by high-performance thin-layer chromatography-multienzyme inhibition assay
Akle_2012_PLoS.One_7_e37593F-spondin/spon1b expression patterns in developing and adult zebrafish
Al-Aqaba_2012_Am.J.Ophthalmol_153_258The effect of standard and transepithelial ultraviolet collagen cross-linking on human corneal nerves: an ex vivo study
Al-Aqaba_2012_Am.J.Ophthalmol_153_29Organization of the regenerated nerves in human corneal grafts
Al-Jafari_2012_Int.J.Mol.Sci_13_7559DNA polymorphisms of the lipoprotein lipase gene and their association with coronary artery disease in the Saudi population
AlSharari_2012_J.Pharmacol.Exp.Ther_342_742The antinociceptive effects of nicotinic partial agonists varenicline and sazetidine-A in murine acute and tonic pain models
Albani_2012_J.Alzheimers.Dis_30_745Replication study to confirm the role of CYP2D6 polymorphism rs1080985 on donepezil efficacy in Alzheimer's disease patients
Albrecht_2012_Mol.Cell.Neurosci_49_364SPARC prevents maturation of cholinergic presynaptic terminals
Alcaide_2012_PLoS.ONE_7_E51521Gene sets for utilization of primary and secondary nutrition supplies in the distal gut of endangered Iberian lynx
Alcantara-Gonzalez_2012_Synapse_66_938Combined administration of cerebrolysin and donepezil induces plastic changes in prefrontal cortex in aged mice
Alder_2012_Science_335_1348The path from beta-carotene to carlactone, a strigolactone-like plant hormone
Aldunate_2012_Biometals_25_815Synaptic defects associated with s-inclusion body myositis are prevented by copper
Alexander_2012_Psychopharmacology.(Berl)_220_627Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine
Alexoudi_2012_Mov.Disord_27_1738Mutations in the phospholipid remodeling gene SERAC1 cause MEGDEL syndrome
Alhamoruni_2012_Br.J.Pharmacol_165_2598Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability
Alhanash_2012_Dalton.Trans_41_10211Formation of M4Se4 cuboids (M = As, Sb, Bi) via secondary pnictogen-chalcogen interactions in the co-crystals MX3.Se=P(p-FC6)H4)3 (M = As, X = Br; M = Sb, X = Cl; M = Bi, X = Cl, Br)
Alhouayek_2012_Trends.Mol.Med_18_615The endocannabinoid system in inflammatory bowel diseases: from pathophysiology to therapeutic opportunity
Ali_2012_CNS.Neurol.Disord.Drug.Targets_11_993Elicitation of Dopaminergic Features of Parkinson's Disease in C. elegans by Monocrotophos, an Organophosphorous Insecticide
Ali_2012_Nat.Prod.Commun_7_257Chemical composition and biological activity of essential oil from Pulicaria undulata from Yemen
Ali_2012_Protein.J_31_229Purification and characterisation of an F16L mutant of a thermostable lipase
Aliczki_2012_Behav.Pharmacol_23_348The temporal dynamics of the effects of monoacylglycerol lipase blockade on locomotion, anxiety, and body temperature
Alikatte_2012_Brain.Dev_34_844Antiamnesic activity of Syzygium cumini against scopolamine induced spatial memory impairments in rats
Alipour_2012_Bioorg.Med.Chem_20_7214Novel coumarin derivatives bearing N-benzyl pyridinium moiety: Potent and dual binding site acetylcholinesterase inhibitors
Allard_2012_BMC.Genomics_13_32High resolution clustering of Salmonella enterica serovar Montevideo strains using a next-generation sequencing approach
Allard_2012_J.Neurosci_32_2002Impact of the NGF maturation and degradation pathway on the cortical cholinergic system phenotype
Allard_2012_Neurobiol.Aging_33_1466Correlation of cognitive performance and morphological changes in neocortical pyramidal neurons in aging
Alonso-Vega_2012_J.Bacteriol_194_4135Genome sequence of Micromonospora lupini Lupac 08, isolated from root nodules of Lupinus angustifolius
Aloulou_2012_Methods.Mol.Biol_861_63Phospholipases: an overview
Alout_2012_PLoS.One_7_e47125Novel AChE inhibitors for sustainable insecticide resistance management
Alper_2012_J.Ethnopharmacol_139_879Ibogaine and the inhibition of acetylcholinesterase
Althabegoiti_2012_J.Bacteriol_194_6651Genome sequence of Rhizobium grahamii CCGE502, a broad-host-range symbiont with low nodulation competitiveness in Phaseolus vulgaris
Aluigi_2012_Curr.Drug.Targets_13_587The sea urchin, Paracentrotus lividus, as a model to investigate the onset of molecules immunologically related to the alpha-7 subunit of nicotinic receptors during embryonic and larval development
Alvarez_2012_J.Bacteriol_194_5449Draft genome sequence of Pseudomonas sp. strain Ag1, isolated from the midgut of the malaria mosquito Anopheles gambiae
Amara_2012_Biochim.Biophys.Acta_1821_1379Inhibition of phospholipase A1, lipase and galactolipase activities of pancreatic lipase-related protein 2 by methyl arachidonyl fluorophosphonate (MAFP)
Amaro_2012_J.Bacteriol_194_1613Whole-genome sequence of the human pathogen Legionella pneumophila serogroup 12 strain 570-CO-H
Ambrus_2012_Chem.Commun.(Camb)_48_6699Covalent attachment of antagonists to the alpha7 nicotinic acetylcholine receptor: synthesis and reactivity of substituted maleimides
Amenta_2012_J.Neurol.Sci_322_96The ASCOMALVA trial: Association between the cholinesterase inhibitor donepezil and the cholinergic precursor choline alphoscerate in Alzheimer's disease with cerebrovascular injury: Interim results
Amenta_2012_J.Neurosci_32_2324Biglycan is an extracellular MuSK binding protein important for synapse stability
Amoo_2012_BMC.Complement.Altern.Med_12_87Antioxidant and acetylcholinesterase-inhibitory properties of long-term stored medicinal plants
Amoo_2012_Phytother.Res_26_639Acetylcholinesterase inhibition, antioxidant, antiinflammatory, antimicrobial and phytochemical properties of Huernia hystrix
An_2012_Neurobiol.Learn.Mem_100C_18Melamine induced spatial cognitive deficits associated with impairments of hippocampal long-term depression and cholinergic system in Wistar rats
Anand_2012_Bioorg.Med.Chem_20_1175A review on coumarins as acetylcholinesterase inhibitors for Alzheimer's disease
Anand_2012_Bioorg.Med.Chem_20_521Synthesis and evaluation of novel 4-[(3H,3aH,6aH)-3-phenyl)-4,6-dioxo-2-phenyldihydro-2H-pyrrolo[3,4-d]isoxazol-5(3 H,6H,6aH)-yl]benzoic acid derivatives as potent acetylcholinesterase inhibitors and anti-amnestic agents
Anand_2012_J.Bacteriol_194_4471Genome sequence of Sphingobium indicum B90A, a hexachlorocyclohexane-degrading bacterium
Ancrenaz_2012_Br.J.Pharmacol_166_2362The paraoxonase-1 pathway is not a major bioactivation pathway of clopidogrel in vitro
Andersen_2012_BMC.Neurol_12_59The effect of stimulation therapy and donepezil on cognitive function in Alzheimer's disease. A community based RCT with a two-by-two factorial design
Andersen_2012_PLoS.One_7_e36830Paraoxonase 1 polymorphism and prenatal pesticide exposure associated with adverse cardiovascular risk profiles at school age
Anderson_2012_J.Pharm.Pract_25_61Emergency management of chemical weapons injuries
Anderson_2012_PLoS.One_7_e48665Low dose nicotine and antagonism of beta2 subunit containing nicotinic acetylcholine receptors have similar effects on affective behavior in mice
Anderson_2012_Pestic.Biochem.Physiol_102_124Acetylcholinesterase inhibition by nootkatone and carvacrol in arthropods
Anderson_2012_Stand.Genomic.Sci_6_174Genome sequence of the homoacetogenic bacterium Holophaga foetida type strain (TMBS4(T))
Anderson_2012_Stand.Genomic.Sci_6_31Complete genome sequence of Halopiger xanaduensis type strain (SH-6(T))
Anderson_2012_Stand.Genomic.Sci_7_210Genome sequence of the flexirubin-pigmented soil bacterium Niabella soli type strain (JS13-8(T))
Andersson_2012_Annu.Rev.Immunol_30_313Reflex principles of immunological homeostasis
Andexer_2012_Chembiochem_13_1932Hydroxynitrile lyases with alpha/beta-hydrolase fold: two enzymes with almost identical 3D structures but opposite enantioselectivities and different reaction mechanisms
Angkawidjaja_2012_Febs.J_279_3071Structure and stability of a thermostable carboxylesterase from the thermoacidophilic archaeon Sulfolobus tokodaii.
Anker_2012_Biol.Psychiatry_71_700Cocaine hydrolase encoded in viral vector blocks the reinstatement of cocaine seeking in rats for 6 months
Annweiler_2012_Drugs.Aging_29_81Possibility of a new anti-alzheimer's disease pharmaceutical composition combining memantine and vitamin D
Ansari_2012_Neurotox.Res_22_292Cholinergic dysfunctions and enhanced oxidative stress in the neurobehavioral toxicity of lambda-cyhalothrin in developing rats
Antequera_2012_J.Alzheimers.Dis_29_187Encapsulated VEGF-secreting cells enhance proliferation of neuronal progenitors in the hippocampus of AbetaPP/Ps1 mice
Antequera_2012_Neurobiol.Dis_46_682Effects of a tacrine-8-hydroxyquinoline hybrid (IQM-622) on Abeta accumulation and cell death: involvement in hippocampal neuronal loss in Alzheimer's disease
Antwerpen_2012_J.Bacteriol_194_6360Draft genome sequence of Bacillus anthracis BF-1, isolated from Bavarian cattle
Anwar_2012_Pharmacol.Biochem.Behav_103_386Effects of caffeic acid on behavioral parameters and on the activity of acetylcholinesterase in different tissues from adult rats
Anzilotti_2012_Brain.Res.Bull_87_350Immunohistochemical localization of receptor for advanced glycation end (RAGE) products in the R6/2 mouse model of Huntington's disease
Anzolin_2012_Mar.Pollut.Bull_64_1402Contaminant concentrations, biochemical and hematological biomarkers in blood of West Indian manatees Trichechus manatus from Brazil
Apostol_2012_Psychopharmacology.(Berl)_219_715Efficacy and safety of the novel alpha(4)beta(2) neuronal nicotinic receptor partial agonist ABT-089 in adults with attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled crossover study
Aragones_2012_J.Lipid.Res_53_168Serum paraoxonase-3 concentration in HIV-infected patients. Evidence for a protective role against oxidation
Araoud_2012_J.Expo.Sci.Environ.Epidemiol_22_243Adverse effects of pesticides on biochemical and haematological parameters in Tunisian agricultural workers
Archana_2012_Neurochem.Res_37_330Altered biochemical parameters in saliva of pediatric attention deficit hyperactivity disorder
Argandona_2012_Brain.Res_1473_141Effect of intracortical vascular endothelial growth factor infusion and blockade during the critical period in the rat visual cortex
Arias_2012_Neurochem.Int_61_1433Structural and functional interaction of (+/-)-2-(N-tert-butylamino)-3'-iodo-4'-azidopropiophenone, a photoreactive bupropion derivative, with nicotinic acetylcholine receptors
Arif_2012_Appl.Environ.Microbiol_78_6128Novel dehalogenase mechanism for 2,3-dichloro-1-propanol utilization in Pseudomonas putida strain MC4
Arima_2012_J.Lipid.Res_53_513Surface loops of extracellular phospholipase A(1) determine both substrate specificity and preference for lysophospholipids
Arlt_2012_Neurochem.Res_37_2706Effect of one-year vitamin C- and e-supplementation on cerebrospinal fluid oxidation parameters and clinical course in Alzheimer's disease
Arnaldi_2012_Q.J.Nucl.Med.Mol.Imaging_56_55Cognitive impairment in degenerative parkinsonisms: role of radionuclide brain imaging
Arons_2012_J.Neurosci_32_14966Autism-Associated Mutations in ProSAP2/Shank3 Impair Synaptic Transmission and Neurexin-Neuroligin-Mediated Transsynaptic Signaling
Arredondo_2012_Mini.Rev.Med.Chem_12_1301Some clinical applications of the electrochemical biosensors
Arrigoni_2012_J.Prev.Med.Hyg_53_14Prevention in the workplace and training of personnel: new methodological approaches
Arroyo_2012_J.Neurosci_32_3859Prolonged disynaptic inhibition in the cortex mediated by slow, non-alpha7 nicotinic excitation of a specific subset of cortical interneurons
Arruda_2012_Molecules_17_3082Anti-acetylcholinesterase and antioxidant activity of essential oils from Hedychium gardnerianum Sheppard ex Ker-Gawl
Arumugam_2012_Lancet_379_492A lethal injection?
Aryal_2012_Anal.Chim.Acta_723_68Identification of phosphorylated butyrylcholinesterase in human plasma using immunoaffinity purification and mass spectrometry
Ascione_2012_Biochem.Biophys.Res.Commun_420_542Native expression and purification of hormone-sensitive lipase from Psychrobacter sp. TA144 enhances protein stability and activity
Ashare_2012_Drug.Alcohol.Depend_126_263Cognitive effects of the acetylcholinesterase inhibitor, donepezil, in healthy, non-treatment seeking smokers: A pilot feasibility study
Ashraf_2012_Bioorg.Med.Chem.Lett_22_508AChE inhibitor: a regio- and stereo-selective 1,3-dipolar cycloaddition for the synthesis of novel substituted 5,6-dimethoxy spiro[5.3']-oxindole-spiro-[6.3'']-2,3-dihydro-1H-inden-1''-one-7-(substituted aryl)-tetrahydro-1H-pyrrolo[1,2-c][1,3]thiazole
Askmark_2012_Eur.J.Neurol_19_1554Vitamin D deficiency in patients with myasthenia gravis and improvement of fatigue after supplementation of vitamin D3: a pilot study
Assaf_2012_J.Physiol.Biochem_68_77Biochemical and genetic alterations of oxidant/antioxidant status of the brain in rats treated with dexamethasone: protective roles of melatonin and acetyl-L-carnitine
Assis_2012_Sci.Total.Environ_441C_141Comparative effect of pesticides on brain acetylcholinesterase in tropical fish
Assumpcao_2012_Am.J.Trop.Med.Hyg_86_1005An insight into the sialotranscriptome of Triatoma matogrossensis, a kissing bug associated with fogo selvagem in South America
Ataya_2012_Molecules_17_10399Cloning, phylogenetic analysis and 3D modeling of a putative lysosomal acid lipase from the camel, Camelus dromedarius
Atreya_2012_Int.J.Environ.Health.Res_22_401Knowledge, attitude and practices of pesticide use and acetylcholinesterase depression among farm workers in Nepal
Atri_2012_Neurodegener.Dis_10_170Validity, significance, strengths, limitations, and evidentiary value of real-world clinical data for combination therapy in Alzheimer's disease: comparison of efficacy and effectiveness studies
Attrey_2012_Indian.J.Exp.Biol_50_690Effect of seabuckthorn extract on scopolamine induced cognitive impairment
Aufauvre_2012_Sci.Rep_2_326Parasite-insecticide interactions: a case study of Nosema ceranae and fipronil synergy on honeybee
Auger_2012_J.Bacteriol_194_1630Complete genome sequence of the highly hemolytic strain Bacillus cereus F837/76
Augustyniak_2012_Protein.Sci_21_487Biophysical characterization of mutants of Bacillus subtilis lipase evolved for thermostability: factors contributing to increased activity retention
Auldridge_2012_Plant.Cell_24_1596Emergent decarboxylase activity and attenuation of alpha/beta-hydrolase activity during the evolution of methylketone biosynthesis in tomato
Ausborn_2012_Proc.Natl.Acad.Sci.U.S.A_109_E3631Decoding the rules of recruitment of excitatory interneurons in the adult zebrafish locomotor network
Avdjieva-Tzavella_2012_Genet.Couns_23_505Analysis of the genes encoding neuroligins NLGN3 and NLGN4 in Bulgarian patients with autism
Aviram_2012_Curr.Opin.Lipidol_23_169Atherosclerosis: cell biology and lipoproteins - paraoxonases protect against atherosclerosis and diabetes development
Awasthi_2012_Sci.Pharm_80_647Chronic inhibition of central Angiotensin-converting enzyme ameliorates colchicine-induced memory impairment in mice
Axelsson_2012_J.Bacteriol_194_2391Genome sequence of the naturally plasmid-free Lactobacillus plantarum strain NC8 (CCUG 61730)
Aydin-Sinan_2012_J.Environ.Sci.Health.B_47_397Toxic effects of deltamethrin and lambda-cyhalothrin on Xenopus laevis tadpoles
Baba_2012_Exp.Ther.Med_4_452Reduction of oxidative stress in liver cancer patients by oral green tea polyphenol tablets during hepatic arterial infusion chemotherapy
Baba_2012_J.Org.Chem_77_1675Complementary and synergistic roles in enzyme-catalyzed regioselective and complete hydrolytic deprotection of O-acetylated beta-D-glucopyranosides of N-arylacetohydroxamic acids
Bachovchin_2012_Nat.Rev.Drug.Discov_11_52The pharmacological landscape and therapeutic potential of serine hydrolases
Badin_2012_J.Lipid.Res_53_839Regulation of skeletal muscle lipolysis and oxidative metabolism by the co-lipase CGI-58
Badiou-Beneteau_2012_Ecotoxicol.Environ.Saf_82_22Development of biomarkers of exposure to xenobiotics in the honey bee Apis mellifera: application to the systemic insecticide thiamethoxam
Bae_2012_Pharm.Biol_50_900Inhaled essential oil from Chamaecyparis obtuse ameliorates the impairments of cognitive function induced by injection of beta-amyloid in rats
Bahar_2012_J.Pharm.Sci_101_3979Species difference of esterase expression and hydrolase activity in plasma
Bahl_2012_Protein.Pept.Lett_19_186Pseudomonas aeruginosa Cif defines a distinct class of alpha/beta epoxide hydrolases utilizing a His/Tyr ring-opening pair
Bahri_2012_Nat.Prod.Res_26_298Capture of sunflower seedlings lipase using polyclonal antibodies
Bailey_2012_Biol.Psychiatry_71_120Nicotinic alpha5 subunits drive developmental changes in the activation and morphology of prefrontal cortex layer VI neurons
Bain_2012_J.Clin.Psychiatry_73_783A randomized pilot study of the efficacy and safety of ABT-089, a novel alpha4beta2 neuronal nicotinic receptor agonist, in adults with attention-deficit/hyperactivity disorder
Bajgar_2012_Mil.Med.Sci.Lett_81_164From the research of cholinesterase reactivators to the effective therapy of organophosphate/nerve agent poisoning
Bajgar_2012_Toxicol.Mech.Methods_22_60Combined approach to demonstrate acetylcholinesterase activity changes in the rat brain following tabun intoxication and its treatment
Baker_2012_Appl.Microbiol.Biotechnol_93_229Identification and comparison of cutinases for synthetic polyester degradation
Bal-Price_2012_ALTEX_29_202Advancing the science of developmental neurotoxicity (DNT): testing for better safety evaluation
Bala_2012_Environ.Sci.Technol_46_4051Enzymatic conversion of -hexachlorocyclohexane and a heptachlorocyclohexane isomer, two neglected components of technical hexachlorocyclohexane
Balaconis_2012_Anal.Chem_84_5787Biodegradable optode-based nanosensors for in vivo monitoring
Balali-Mood_2012_Iran.J.Med.Sci_37_74Recent advances in the treatment of organophosphorous poisonings
Balali-Mood_2012_Iran.J.Public.Health_41_1Health aspects of organophosphorous pesticides in asian countries
Baldessari_2012_Methods.Mol.Biol_861_445Lipases as catalysts in synthesis of fine chemicals
Baldessari_2012_Methods.Mol.Biol_861_457Lipases in green chemistry: acylation and alcoholysis on steroids and nucleosides
Ballok_2012_J.Bacteriol_194_5315Epoxide-mediated CifR repression of cif gene expression utilizes two binding sites in Pseudomonas aeruginosa
Banerjee_2012_Biochem.Pharmacol_84_1078Kynurenic acid inhibits glutamatergic transmission to CA1 pyramidal neurons via alpha7 nAChR-dependent and -independent mechanisms
Banerjee_2012_J.Pharmacol.Exp.Ther_341_500Regulation of GABAergic inputs to CA1 pyramidal neurons by nicotinic receptors and kynurenic acid
Banerjee_2012_Protein.J_31_306Characterization of tannase protein sequences of bacteria and fungi: an in silico study
Banks_2012_Neurotoxicol_33_575A review of experimental evidence linking neurotoxic organophosphorus compounds and inflammation
Bannantine_2012_BMC.Genomics_13_89Genome sequencing of ovine isolates of Mycobacterium avium subspecies paratuberculosis offers insights into host association
Bargar_2012_Environ.Toxicol.Chem_31_2124The relationship between total cholinesterase activity and mortality in four butterfly species
Barichello_2012_Microbiol.Immunol_56_191Acetylcholinesterase activity in the rat brain after pneumococcal meningitis
Barreau_2012_J.Bacteriol_194_901Draft genome sequence of probiotic strain Pediococcus acidilactici MA18/5M
Barreiro_2012_J.Bacteriol_194_3756Draft genome of Streptomyces tsukubaensis NRRL 18488, the producer of the clinically important immunosuppressant tacrolimus (FK506)
Barrera-Rivera_2012_Methods.Mol.Biol_861_485Synthesis of biodegradable polymers using biocatalysis with Yarrowia lipolytica lipase
Barretto_2012_J.Bacteriol_194_5959Genome sequence of the lantibiotic bacteriocin producer Streptococcus salivarius strain K12
Bartolucci_2012_Biochem.J_444_269Kinetics of Torpedo californica acetylcholinesterase inhibition by bisnorcymserine and crystal structure of the complex with its leaving group
Bartzokis_2012_Neuropharmacol_62_2137Neuroglialpharmacology: myelination as a shared mechanism of action of psychotropic treatments
Bas_2012_J.Neurochem_123 Suppl 2_138Plasma 3-nitrotyrosine estimates the reperfusion-induced cerebrovascular stress, whereas matrix metalloproteinases mainly reflect plasma activity: a study in patients treated with thrombolysis or endovascular recanalization
Basel_2012_Small_8_913A cell-delivered and cell-activated SN38-dextran prodrug increases survival in a murine disseminated pancreatic cancer model
Basha_2012_Biol.Trace.Elem.Res_150_306Combined impact of exercise and temperature in learning and memory performance of fluoride toxicated rats
Basha_2012_Int.J.Dev.Neurosci_30_343Perinatal lead exposure alters postnatal cholinergic and aminergic system in rat brain: reversal effect of calcium co-administration
Baskys_2012_Exp.Gerontol_47_887Pharmacological prevention and treatment of vascular dementia: Approaches and perspectives
Bassegoda_2012_Appl.Environ.Microbiol_78_1724Rhodococcus sp. Strain CR-53 LipR, the First Member of a New Bacterial Lipase Family (Family X) Displaying an Unusual Y-Type Oxyanion Hole, Similar to the Candida antarctica Lipase Clan
Basselin_2012_Brain.Res.Bull_87_154Imaging brain signal transduction and metabolism via arachidonic and docosahexaenoic acid in animals and humans
Basso_2012_Environ.Sci.Pollut.Res.Int_19_214Plasma esterases in the tegu lizard Tupinambis merianae (Reptilia, Teiidae): impact of developmental stage, sex, and organophosphorus in vitro exposure
Basta_2012_Clin.Neurol.Neurosurg_114_795MuSK myasthenia gravis and Lambert-Eaton myasthenic syndrome in the same patient
Basu_2012_Sci.Total.Environ_414_205Extracts from hardwood trees used in commercial paper mills contain biologically active neurochemical disruptors
Batistella_2012_Bioprocess.Biosyst.Eng_35_351Assessment of two immobilized lipases activity and stability to low temperatures in organic solvents under ultrasound-assisted irradiation
Batistella_2012_Ultrason.Sonochem_19_452Ultrasound-assisted lipase-catalyzed transesterification of soybean oil in organic solvent system
Batulevicius_2012_Auton.Neurosci_168_14Distribution, structure and projections of the frog intracardiac neurons
Baudouin_2012_Science_338_128Shared synaptic pathophysiology in syndromic and nonsyndromic rodent models of autism
Bayrak_2012_Gynecol.Endocrinol_28_874Paraoxonase lactonase activity (PON-HTLase), asymmetric dimethylarginine (ADMA) and platelet activating factor-acetylhydrolase (PAF-AH) activity in non-obese women with PCOS
Bayrak_2012_J.Atheroscler.Thromb_19_376Serum PON-1 activity but not Q192R polymorphism is related to the extent of atherosclerosis
Bayrami_2012_Toxicol.Ind.Health_28_90Electroencephalogram, cognitive state, psychological disorders, clinical symptom, and oxidative stress in horticulture farmers exposed to organophosphate pesticides
Beebe_2012_Bioorg.Med.Chem_20_4128Synthesis and SAR of 4-aminocyclopentapyrrolidines as N-type Ca(2)(+) channel blockers with analgesic activity
Beisson_2012_Curr.Opin.Plant.Biol_15_329Solving the puzzles of cutin and suberin polymer biosynthesis
Beisson_2012_Nat.Chem.Biol_8_603Plants: Knitting a polyester skin
Belaya_2012_Am.J.Hum.Genet_91_193Mutations in DPAGT1 cause a limb-girdle congenital myasthenic syndrome with tubular aggregates
Belaya_2012_Ann.N.Y.Acad.Sci_1275_29Identification of DPAGT1 as a new gene in which mutations cause a congenital myasthenic syndrome
Belecki_2012_Angew.Chem.Int.Ed.Engl_51_11316Environmental control of the calicheamicin polyketide synthase leads to detection of a programmed octaketide and a proposal for enediyne biosynthesis
Belinskaya_2012_Biochim.Biophys.Acta_1824_701Differences in amino acid residues in the binding pockets dictate substrate specificities of mouse senescence marker protein-30, human paraoxonase1, and squid diisopropylfluorophosphatase
Bell_2012_Aust.Fam.Physician_41_45Anticholinergic and sedative medicines - prescribing considerations for people with dementia
Bellgard_2012_Int.J.Parasitol_42_161CattleTickBase: an integrated Internet-based bioinformatics resource for Rhipicephalus (Boophilus) microplus
Belligni_2012_Eur.J.Med.Genet_55_222790 Kb microduplication in chromosome band 17p13.1 associated with intellectual disability, afebrile seizures, dysmorphic features, diabetes, and hypothyroidism
Bellusci_2012_Biomacromolecules_13_805Lipase immobilization on differently functionalized vinyl-based amphiphilic polymers: influence of phase segregation on the enzyme hydrolytic activity
Ben Ali_2012_Biochimie_94_137The molecular mechanism of human hormone-sensitive lipase inhibition by substituted 3-phenyl-5-alkoxy-1,3,4-oxadiazol-2-ones
Ben Ali_2012_Methods.Mol.Biol_861_31Lipases or esterases: does it really matter? Toward a new bio-physico-chemical classification
Ben Amara_2012_Toxicol.Ind.Health_28_222Dimethoate-induced oxidative damage in erythrocytes of female adult rats: possible protective effect of vitamin E and selenium supplemented to diet
Ben Oujji_2012_Sensors.(Basel)_12_7893Acetylcholinesterase immobilized on magnetic beads for pesticides detection: application to olive oil analysis
Ben-Ari_2012_J.Cell.Mol.Med_16_555Similar cation channels mediate protection from cerebellar exitotoxicity by exercise and inheritance
Ben-David_2012_J.Mol.Biol_418_181Catalytic versatility and backups in enzyme active sites: the case of serum paraoxonase 1
Benatar_2012_Ann.N.Y.Acad.Sci_1275_17Design of the Efficacy of Prednisone in the Treatment of Ocular Myasthenia (EPITOME) trial
Bencherif_2012_Med.Hypotheses_78_594Alpha7 nicotinic cholinergic neuromodulation may reconcile multiple neurotransmitter hypotheses of schizophrenia
Benes_2012_Brain.Res.Bull_87_511The restructuring of dopamine receptor subtype gene transcripts in c-fos KO mice
Beninca_2012_Environ.Monit.Assess_184_2045Chronic genetic damages in Geophagus brasiliensis exposed to anthropic impact in estuarine lakes at Santa Catarina coast--southern of Brazil
Bennett_2012_J.Neurochem_123_911Xenopus laevis RIC-3 enhances the functional expression of the C. elegans homomeric nicotinic receptor, ACR-16, in Xenopus oocytes
Bennett_2012_J.Neurosci_32_17287Mechanisms Generating Dual-Component Nicotinic EPSCs in Cortical Interneurons
Bennetzen_2012_Nat.Biotechnol_30_555Reference genome sequence of the model plant Setaria
Bentley_2012_J.Cardiovasc.Pharmacol_60_390Evidence of a drug-drug interaction linked to inhibition of ester hydrolysis by orlistat
Bentley_2012_PLoS.Negl.Trop.Dis_6_E1552The genome of Mycobacterium africanum West African 2 reveals a lineage-specific locus and genome erosion common to the M. tuberculosis complex
Berg_2012_Angew.Chem.Int.Ed.Engl_51_12716Similar but different: thermodynamic and structural characterization of a pair of enantiomers binding to acetylcholinesterase
Bergeret_2012_J.Biol.Chem_287_33675Biochemical and structural study of the atypical acyltransferase domain from the mycobacterial polyketide synthase Pks13
Berk_2012_Int.J.Alzheimers.Dis_2012_707468Broader considerations of higher doses of donepezil in the treatment of mild, moderate, and severe Alzheimer's disease
Berkov_2012_J.Mass.Spectrom_47_1065GC-MS of amaryllidaceous galanthamine-type alkaloids
Berman_2012_Int.J.Hyg.Environ.Health_215_138Human biomonitoring in Israel: past, present, future
Bernardino_2012_Org.Med.Chem.Lett_2_3Synthesis and anti-HSV-1 evaluation of new 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridines and 3H-pyrido[2,3-b]pyrazolo[3,4-h]-1,6-naphthyridines
Berrettini_2012_Mol.Psychiatry_17_856The CHRNA5-A3-B4 gene cluster in nicotine addiction
Besnard_2012_Nature_492_215Automated design of ligands to polypharmacological profiles
Bestel_2012_J.Neurosci.Methods_211_168A novel automated spike sorting algorithm with adaptable feature extraction
Bethea_2012_J.Neurosci.Res_90_1324Effect of ovarian steroids on gene expression related to synapse assembly in serotonin neurons of macaques
Bezerra_2012_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_68_214Crystallization and preliminary X-ray diffraction analysis of human dipeptidyl peptidase 10 (DPPY), a component of voltage-gated potassium channels
Bezerra_2012_PLoS.One_7_e43019Structures of human DPP7 reveal the molecular basis of specific inhibition and the architectural diversity of proline-specific peptidases
Bhadra_2012_Nat.Prod.Res_26_1519Cholinesterase inhibition activity of Marsilea quadrifolia Linn. an edible leafy vegetable from West Bengal, India
Bhardwaj_2012_Chem.Biol.Interact_198_57Single dose exposure of sarin and physostigmine differentially regulates expression of choline acetyltransferase and vesicular acetylcholine transporter in rat brain
Bhargava_2012_Br.J.Pharmacol_167_1301Allosteric nature of P2X receptor activation probed by photoaffinity labelling
Bhargava_2012_Int.J.Pediatr.Otorhinolaryngol_76_149Plasma pseudo cholinesterase deficiency leading to seven hour apnoea in a child undergoing adeno-tonsillectomy
Bharti_2012_J.Biochem.Mol.Toxicol_26_10Buffalo (Bubalus bubalis) epiphyseal proteins give protection from arsenic and fluoride-induced adverse changes in acetylcholinesterase activity in rats
Bhattacharjee_2012_Eur.J.Med.Chem_49_229Discovery of non-oxime reactivators using an in silico pharmacophore model of oxime reactivators of OP-inhibited acetylcholinesterase
Bhattacharjee_2012_Med.Chem_8_230An in silico stereo-electronic comparison of conventional pyridinium oximes and K-oximes for organophosphate (OP) poisoning
Bhattamisra_2012_Pharm.Biol_50_766Effect of standardized extract of Marsilea minuta on learning and memory performance in rat amnesic models
Bi_2012_PLoS.One_7_e51670Fo Shou San, an ancient Chinese herbal decoction, protects endothelial function through increasing endothelial nitric oxide synthase activity
Bi_2012_Planta.Med_78_122Fo shou san, an ancient herbal decoction prepared from angelicae sinensis radix and chuanxiong rhizoma, induces erythropoietin expression: a signaling mediated by the reduced degradation of hypoxia-inducible factor in cultured liver cells
Bian_2012_J.Bacteriol_194_908Genome sequences of six Pseudoalteromonas strains isolated from Arctic sea ice
Biberoglu_2012_Febs.J_279_3844The proline-rich tetramerization peptides in equine serum butyrylcholinesterase
Bidzan_2012_Neurol.Sci_33_1459Withdrawal syndrome after donepezil cessation in a patient with dementia
Bidzan_2012_Psychiatr.Pol_46_361[Impact of treatment with acetylcholinesterase inhibitors, valproic acid and antipsychotics on aggressive behaviour in Alzheimer's type dementia]
Biedermannova_2012_J.Biol.Chem_287_29062A single mutation in a tunnel to the active site changes the mechanism and kinetics of product release in haloalkane dehalogenase LinB
Biely_2012_Biotechnol.Adv_30_1575Microbial carbohydrate esterases deacetylating plant polysaccharides
Bieszczad_2012_Synapse_66_418Nicotinic acetylcholine receptors in rat forebrain that bind (1)(8)F-nifene: relating PET imaging, autoradiography, and behavior
Billen_2012_Proc.Natl.Acad.Sci.U.S.A_109_9173Molecular actions of smoking cessation drugs at alpha4beta2 nicotinic receptors defined in crystal structures of a homologous binding protein
Billings_2012_Neuroreport_23_49ELKS1 and Ca(2+) channel subunit beta4 interact and colocalize at cerebellar synapses
Bimpis_2012_Metab.Brain.Dis_27_221Activation of acetylcholinesterase after U-74389G administration in a porcine model of intracerebral hemorrhage
Binder_2012_Genome.Biol_13_R40A high-throughput approach to identify genomic variants of bacterial metabolite producers at the single-cell level
Biradar_2012_Eur.J.Pharmacol_683_140Neuropharmacological effect of Mangiferin on brain cholinesterase and brain biogenic amines in the management of Alzheimer's disease
Birner-Gruenberger_2012_Insect.Biochem.Mol.Biol_42_220Functional fat body proteomics and gene targeting reveal in vivo functions of Drosophila melanogaster a-Esterase-7
Birner-Gruenberger_2012_Proteomics_12_2482Proteomic characterization of the abdominal ganglion of Aplysia californica-a protein resource for neuroscience
Bitencourt_2012_Arch.Pharm.(Weinheim)_345_723The MIA-QSAR Method for the Prediction of Bioactivities of Possible Acetylcholinesterase Inhibitors
Bithu_2012_Pharm.Biol_50_1241Prosopis cineraria: a potential nootropic agent
Black_2012_Cent.Nerv.Syst.Agents.Med.Chem_12_114Choline transporter CHT regulation and function in cholinergic neurons
Blanc_2012_Genome.Biol_13_R39The genome of the polar eukaryotic microalga Coccomyxa subellipsoidea reveals traits of cold adaptation
Blom_2012_J.Bacteriol_194_1845The complete genome of Bacillus amyloliquefaciens subsp. plantarum CAU B946 contains a gene cluster for nonribosomal synthesis of iturin A
Blotnick-Rubin_2012_Eur.J.Neurosci_36_3077Changes in acetylcholinesterase in experimental autoimmune myasthenia gravis and in response to treatment with a specific antisense
Blum_2012_J.Bacteriol_194_3732Genome analysis of bovine-mastitis-associated Escherichia coli O32:H37 strain P4
Bo_2012_Comp.Biochem.Physiol.Part.D.Genomics.Proteomics_7_191Identification of differentially expressed genes and quantitative expression of complement genes in the liver of marine medaka Oryzias melastigma challenged with Vibrio parahaemolyticus
Bock_2012_Nat.Commun_3_1044The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling
Boda-Heggemann_2012_Radiat.Oncol_7_92Hypofractionated image-guided breath-hold SABR (stereotactic ablative body radiotherapy) of liver metastases--clinical results
Bodereau-Dubois_2012_J.Pharmacol.Exp.Ther_341_326Transmembrane potential polarization, calcium influx, and receptor conformational state modulate the sensitivity of the imidacloprid-insensitive neuronal insect nicotinic acetylcholine receptor to neonicotinoid insecticides
Boettger_2012_Environ.Toxicol_27_193Acetyl cholinesterase activity and muscle contraction in the sea urchin Lytechinus variegatus (Lamarck) following chronic phosphate exposure
Bogan_2012_Drug.Test.Anal_4_199Purity of antidotal oxime HI-6 DMS as an active pharmaceutical ingredient for auto-injectors and infusions
Bogan_2012_Drug.Test.Anal_4_208Photostability of antidotal oxime HI-6, impact on drug development
Bogdanski_2012_Clin.Chem.Lab.Med_50_1107Plasma total homocysteine is a determinant of carotid intima-media thickness and circulating endothelial progenitor cells in patients with newly diagnosed hypertension
Bolbecker_2012_Handb.Exp.Pharmacol_208_167Muscarinic agonists and antagonists in schizophrenia: recent therapeutic advances and future directions
Bolourchian_2012_Pak.J.Pharm.Sci_25_607Prolonged release matrix tablet of pyridostigmine bromide: formulation and optimization using statistical methods
Boonman_2012_Planta.Med_78_1562In vitro acanthamoebicidal activity of fusaric acid and dehydrofusaric acid from an endophytic fungus Fusarium sp. Tlau3
Bordia_2012_J.Pharmacol.Exp.Ther_340_612Nicotine reduces antipsychotic-induced orofacial dyskinesia in rats
Bordia_2012_J.Pharmacol.Exp.Ther_342_327Varenicline is a potent partial agonist at alpha6beta2* nicotinic acetylcholine receptors in rat and monkey striatum
Borneman_2012_BMC.Genomics_13_373Comparative analysis of the Oenococcus oeni pan genome reveals genetic diversity in industrially-relevant pathways
Borneman_2012_FEMS.Yeast.Res_12_88The genome sequence of the wine yeast VIN7 reveals an allotriploid hybrid genome with Saccharomyces cerevisiae and Saccharomyces kudriavzevii origins
Borneman_2012_PLoS.ONE_7_E29626Functional divergence in the genus Oenococcus as predicted by genome sequencing of the newly-described species, Oenococcus kitaharae
Bornscheuer_2012_Nature_485_185Engineering the third wave of biocatalysis
Borrel_2012_J.Bacteriol_194_6944Genome sequence of Candidatus Methanomethylophilus alvus Mx1201, a methanogenic archaeon from the human gut belonging to a seventh order of methanogens
Bosak_2012_J.Med.Chem_55_6716Metaproterenol, isoproterenol, and their bisdimethylcarbamate derivatives as human cholinesterase inhibitors
Bottacini_2012_PLoS.One_7_e44229Bifidobacterium asteroides PRL2011 genome analysis reveals clues for colonization of the insect gut
Botte_2012_Mar.Pollut.Bull_65_384Effects of chlorpyrifos on cholinesterase activity and stress markers in the tropical reef fish Acanthochromis polyacanthus
Bouchard_2012_J.Bacteriol_194_6292Genome sequence of Staphylococcus aureus Newbould 305, a strain associated with mild bovine mastitis
Boulin_2012_Nat.Neurosci_15_1374Positive modulation of a Cys-loop acetylcholine receptor by an auxiliary transmembrane subunit
Bourgeois_2012_Cereb.Cortex_22_1007Modulation of the mouse prefrontal cortex activation by neuronal nicotinic receptors during novelty exploration but not by exploration of a familiar environment
Bouzat_2012_J.Physiol.Paris_106_23New insights into the structural bases of activation of Cys-loop receptors
Boyer_2012_Plant.Physiol_159_1524Structure-activity relationship studies of strigolactone-related molecules for branching inhibition in garden pea: molecule design for shoot branching
Boyle_2012_Aquat.Toxicol_126C_116Subtle alterations in swimming speed distributions of rainbow trout exposed to titanium dioxide nanoparticles are associated with gill rather than brain injury
Boyle_2012_J.Bacteriol_194_6343Genome sequence of the swine pathogen Streptococcus suis serotype 2 strain S735
Brabcova_2012_Molecules_17_13813Lipases as tools in the synthesis of prodrugs from racemic 9-(2,3-dihydroxypropyl)adenine
Bramanti_2012_Neurochem.Res_37_2795Cholinergic precursors modulate the expression of heme oxigenase-1, p21 during astroglial cell proliferation and differentiation in culture
Brambilla_2012_Neurosci.Lett_530_155Association between DPP6 polymorphism and the risk of progressive multiple sclerosis in Northern and Southern Europeans
Brandhuber_2012_Toxicology_302_163Detoxification of tabun at physiological pH mediated by substituted beta-cyclodextrin and glucose derivatives containing oxime groups
Brault_2012_PLoS.One_7_e32041Isolation and characterization of EstC, a new cold-active esterase from Streptomyces coelicolor A3(2)
Brazzolotto_2012_Febs.J_279_2905Human butyrylcholinesterase produced in insect cells: huprine-based affinity purification and crystal structure
Breitbart_2012_J.Clin.Oncol_30_1206Evidence-based treatment of delirium in patients with cancer
Brenchley_2012_Nature_491_705Analysis of the bread wheat genome using whole-genome shotgun sequencing
Brigham_2012_AMB.Express_2_26Examination of PHB Depolymerases in Ralstonia eutropha: Further Elucidation of the Roles of Enzymes in PHB Homeostasis
Brimfield_2012_Prog.Mol.Biol.Transl.Sci_112_209Chemicals of military deployments: revisiting Gulf War Syndrome in light of new information
Brimijoin_2012_Future.Med.Chem_4_151Cocaine hydrolase gene therapy for cocaine abuse
Brinkrolf_2012_J.Bacteriol_194_5968Draft genome sequence of Turicella otitidis ATCC 51513, isolated from middle ear fluid from a child with otitis media
Broadbent_2012_BMC.Genomics_13_533Analysis of the Lactobacillus casei supragenome and its influence in species evolution and lifestyle adaptation
Brodaty_2012_Int.Psychogeriatr_24_1034Dementia time to death: a systematic literature review on survival time and years of life lost in people with dementia
Bronicki_2012_Front.Mol.Neurosci_5_36Trans-acting factors governing acetylcholinesterase mRNA metabolism in neurons
Brooks_2012_J.Bacteriol_194_5492Whole-genome shotgun sequence of Rhodococcus species strain JVH1
Brooks_2012_Neuropsychopharmacology_37_2476Transient inactivation of the neonatal ventral hippocampus impairs attentional set-shifting behavior: reversal with an alpha7 nicotinic agonist
Brown_2012_Fungal.Genet.Biol_49_521Identification of gene clusters associated with fusaric acid, fusarin, and perithecial pigment production in Fusarium verticillioides
Brown_2012_J.Bacteriol_194_2383Draft genome sequence of Rhizobium sp. strain PDO1-076, a bacterium isolated from Populus deltoides
Brown_2012_J.Bacteriol_194_3279Draft genome sequence for Microbacterium laevaniformans strain OR221, a bacterium tolerant to metals, nitrate, and low pH
Brown_2012_J.Bacteriol_194_4138Genome annotation of five Mycoplasma canis strains
Brown_2012_J.Bacteriol_194_5147Draft genome sequences for two metal-reducing Pelosinus fermentans strains isolated from a Cr(VI)-contaminated site and for type strain R7
Brown_2012_J.Bacteriol_194_5991Twenty-one genome sequences from Pseudomonas species and 19 genome sequences from diverse bacteria isolated from the rhizosphere and endosphere of Populus deltoides
Brudzynski_2012_Behav.Brain.Res_226_511Quinpirole-induced 50 kHz ultrasonic vocalization in the rat: role of D2 and D3 dopamine receptors
Bruge_2012_Biofactors_38_249Olive oil supplemented with Coenzyme Q(10): effect on plasma and lipoprotein oxidative status
Brundiek_2012_Angew.Chem.Int.Ed.Engl_51_412Creation of a lipase highly selective for trans fatty acids by protein engineering
Brundiek_2012_Appl.Microbiol.Biotechnol_94_141The short form of the recombinant CAL-A-type lipase UM03410 from the smut fungus Ustilago maydis exhibits an inherent trans-fatty acid selectivity
Brunet-Galmes_2012_J.Bacteriol_194_6642Complete genome sequence of the naphthalene-degrading bacterium Pseudomonas stutzeri AN10 (CCUG 29243)
Brunhofer_2012_Bioorg.Med.Chem_20_6669Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: The case of chelerythrine
Bruno_2012_Neurobiol.Aging_33_1927Cortical peroxynitration of nerve growth factor in aged and cognitively impaired rats
Brunzell_2012_Neuropsychopharmacology_37_1134Alpha7 nicotinic acetylcholine receptors modulate motivation to self-administer nicotine: implications for smoking and schizophrenia
Brunzell_2012_Nicotine.Tob.Res_14_1258Preclinical evidence that activation of mesolimbic alpha 6 subunit containing nicotinic acetylcholine receptors supports nicotine addiction phenotype
Brzuszkiewicz_2012_J.Bacteriol_194_4436Complete genome sequence of the B12-producing Shimwellia blattae strain DSM 4481, isolated from a cockroach
Bschleipfer_2012_Life.Sci_91_1077Bladder outlet obstruction influences mRNA expression of cholinergic receptors on sensory neurons in mice
Bschleipfer_2012_Life.Sci_91_1082Does bladder outlet obstruction alter the non-neuronal cholinergic system of the human urothelium?
Bubser_2012_Handb.Exp.Pharmacol_208_121Muscarinic receptor pharmacology and circuitry for the modulation of cognition
Bucaretchi_2012_Clin.Toxicol.(Phila)_50_44Poisoning by illegal rodenticides containing acetylcholinesterase inhibitors (chumbinho): a prospective case series
Buels_2012_Br.J.Pharmacol_165_1501Non-bronchodilating mechanisms of tiotropium prevent airway hyperreactivity in a guinea-pig model of allergic asthma
Buels_2012_Handb.Exp.Pharmacol_208_317Muscarinic receptor antagonists: effects on pulmonary function
Buiculescu_2012_Bioelectrochemistry_86_72The stabilization of Au NP-AChE nanocomposites by biosilica encapsulation for the development of a thiocholine biosensor
Bulgaroni_2012_Environ.Monit.Assess_184_3307Organophosphate pesticide environmental exposure: analysis of salivary cholinesterase and carboxilesterase activities in preschool children and their mothers
Bullangpoti_2012_Pest.Manag.Sci_68_1255Antifeedant activity of Jatropha gossypifolia and Melia azedarach senescent leaf extracts on Spodoptera frugiperda (Lepidoptera: Noctuidae) and their potential use as synergists
Burand_2012_Viruses_4_28Analysis of the genome of the sexually transmitted insect virus Helicoverpa zea nudivirus 2
Burger_2012_J.Lipid.Res_53_43Crystal structure of the predicted phospholipase LYPLAL1 reveals unexpected functional plasticity despite close relationship to acyl protein thioesterases
Burghaus_2012_CNS.Neurosci.Ther_18_149Hallucinations in neurodegenerative diseases
Bursova_2012_J.Neurol.Sci_315_60Expression of growth-associated protein 43 in the skin nerve fibers of patients with type 2 diabetes mellitus
Burton_2012_Neurosci_215_1Distinct roles of neuroligin-1 and SynCAM1 in synapse formation and function in primary hippocampal neuronal cultures
Busek_2012_Int.J.Biochem.Cell.Biol_44_738Dipeptidyl peptidase-IV inhibits glioma cell growth independent of its enzymatic activity
Busquets_2012_J.Bacteriol_194_5477Genome sequence of Pseudomonas stutzeri strain JM300 (DSM 10701), a soil isolate and model organism for natural transformation
Bussolaro_2012_J.Environ.Monit_14_2154Bioaccumulation and related effects of PCBs and organochlorinated pesticides in freshwater fish Hypostomus commersoni
Butcher_2012_Handb.Exp.Pharmacol_208_79Physiological role of G-protein coupled receptor phosphorylation
Butchko_2012_Fungal.Genet.Biol_49_602Lae1 regulates expression of multiple secondary metabolite gene clusters in Fusarium verticillioides
Byrne-Bailey_2012_J.Bacteriol_194_2767Complete genome sequence of the anaerobic perchlorate-reducing bacterium Azospira suillum strain PS
Cabral_2012_Colloids.Surf.B.Biointerfaces_103C_624Computational, electrochemical, and spectroscopic, studies of acetycholinesterase covalently attached to carbon nanotubes
Cacciatore_2012_Aquat.Toxicol_128-129C_124Cholinesterase and carboxylesterase inhibition in Planorbarius corneus exposed to binary mixtures of azinphos-methyl and chlorpyrifos
Cacciatore_2012_Chemosphere_88_450Binary mixtures of azinphos-methyl oxon and chlorpyrifos oxon produce in vitro synergistic cholinesterase inhibition in Planorbarius corneus
Cai_2012_J.Bacteriol_194_4780Genome of Bacillus macauensis ZFHKF-1, a long-chain-forming bacterium
Cai_2012_Neurotox.Res_21_160BACE1 elevation is involved in amyloid plaque development in the triple transgenic model of Alzheimer's disease: differential Abeta antibody labeling of early-onset axon terminal pathology
Cakmak_2012_Clin.Res.Hepatol.Gastroenterol_36_e34Steatohepatitis and liver cirrhosis in Chanarin-Dorfman syndrome with a new ABDH5 mutation
Calabresi_2012_Atherosclerosis_222_299Genetic lecithin:cholesterol acyltransferase deficiency and cardiovascular disease
Calahorro_2012_PLoS.One_7_e39277Functional phenotypic rescue of Caenorhabditis elegans neuroligin-deficient mutants by the human and rat NLGN1 genes
Calas-List_2012_Neurosci.Lett_518_64Nornicotine application on cockroach dorsal unpaired median neurons induces two distinct ionic currents: implications of different nicotinic acetylcholine receptors
Callahan_2012_Neuropharmacol_67C_201Positive allosteric modulator of alpha 7 nicotinic-acetylcholine receptors, PNU-120596 augments the effects of donepezil on learning and memory in aged rodents and non-human primates
Calleja-Macias_2012_Life.Sci_91_1099Association of single nucleotide polymorphisms of nicotinic acetylcholine receptor subunits with cervical neoplasia
Camacho-Garcia_2012_Neurobiol.Dis_47_135Mutations affecting synaptic levels of neurexin-1beta in autism and mental retardation
Camacho-Perez_2012_J.Environ.Manage_95 Suppl_S306Enzymes involved in the biodegradation of hexachlorocyclohexane: a mini review
Camboni_2012_J.Pathol_226_40Induction of a regenerative microenvironment in skeletal muscle is sufficient to induce embryonal rhabdomyosarcoma in p53-deficient mice
Camps_2012_PPAR.Res_2012_616371PPARs in Regulation of Paraoxonases: Control of Oxidative Stress and Inflammation Pathways
Canals_2012_J.Biol.Chem_287_650A Monod-Wyman-Changeux mechanism can explain G protein-coupled receptor (GPCR) allosteric modulation
Canastar_2012_J.Mol.Neurosci_47_389Promoter methylation and tissue-specific transcription of the alpha7 nicotinic receptor gene, CHRNA7
Cantu_2012_Protein.Sci_21_655Acyl carrier protein structural classification and normal mode analysis
Cao_2012_Behav.Neurosci_126_332Nicotine normalizes event related potentials in COMT-Val-tg mice and increases gamma and theta spectral density
Cao_2012_Diabetes.Res.Clin.Pract_96_362Formation of cyclic structure at amino-terminus of glucagon-like peptide-1 exhibited a prolonged half-life in vivo
Cao_2012_Food.Chem.Toxicol_51C_242Characterization of flavonoids from Dryopteris erythrosora and evaluation of their antioxidant, anticancer and acetylcholinesterase inhibition activities
Cao_2012_Int.J.Mol.Sci_13_12232Biocatalytic Synthesis of Poly(delta-Valerolactone) Using a Thermophilic Esterase from Archaeoglobus fulgidus as Catalyst
Cao_2012_J.Bacteriol_194_5146Draft genome sequences of eight Salmonella enterica serotype newport strains from diverse hosts and locations
Cao_2012_J.Neuroinflammation_9_223Alteration of astrocytes and Wnt/beta-catenin signaling in the frontal cortex of autistic subjects
Carloni_2012_Pediatr.Res_72_400Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats
Carneiro_2012_J.Bacteriol_194_6689Genome sequence of Exiguobacterium antarcticum B7, isolated from a biofilm in Ginger Lake, King George Island, Antarctica
Caro-Quintero_2012_J.Bacteriol_194_1236Genome sequencing of five Shewanella baltica strains recovered from the oxic-anoxic interface of the Baltic Sea
Carradori_2012_Expert.Opin.Ther.Pat_22_759Patent-related survey on new monoamine oxidase inhibitors and their therapeutic potential
Carroll_2012_PLoS.One_7_e43536Combined cocaine hydrolase gene transfer and anti-cocaine vaccine synergistically block cocaine-induced locomotion
Carvalho_2012_Pestic.Biochem.Physiol_104_143Chlorpyrifos resistance is associated with mutation and amplification of the acetylcholinesterase-1 gene in the tomato red spider mite, Tetranychus evansi
Casado_2012_J.Lipid.Res_53_2586HSL-knockout mouse testis exhibits class B scavenger receptor upregulation and disrupted lipid raft microdomains
Casado_2012_Methods.Mol.Biol_861_495Phospholipases in food industry: a review
Casas-Godoy_2012_Methods.Mol.Biol_861_3Lipases: an overview
Casida_2012_Environ.Health.Perspect_120_487The greening of pesticide-environment interactions: some personal observations
Castellarin_2012_Genome.Res_22_299Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma
Castellino_2012_Pediatr.Blood.Cancer_59_540Toxicity and efficacy of the acetylcholinesterase (AChe) inhibitor donepezil in childhood brain tumor survivors: a pilot study
Castillo_2012_Insect.Biochem.Mol.Biol_42_404Biosynthesis of ethyl oleate, a primer pheromone, in the honey bee (Apis mellifera L.)
Castillo_2012_Methods.Mol.Biol_861_383Thermodynamical methods for the optimization of lipase-catalyzed reactions
Castro-Ochoa_2012_Appl.Biochem.Biotechnol_166_1275ANCUT2, an extracellular cutinase from Aspergillus nidulans induced by olive oil
Cattaneo_2012_Arch.Environ.Contam.Toxicol_62_97Tissue biochemical alterations of Cyprinus carpio exposed to commercial herbicide containing clomazone under rice-field conditions
Catto_2012_Eur.J.Med.Chem_58C_84Design, synthesis and biological evaluation of benzo[e][1,2,4]triazin-7(1H)-one and [1,2,4]-triazino[5,6,1-jk]carbazol-6-one derivatives as dual inhibitors of beta-amyloid aggregation and acetyl/butyryl cholinesterase
Cecchi_2012_Ecotoxicol.Environ.Saf_80_280Environmental exposure to organophosphate pesticides: assessment of endocrine disruption and hepatotoxicity in pregnant women
Cedillo_2012_Bioengineered_4_Potential of Ophiostoma piceae sterol esterase for biotechnologically relevant hydrolysis reactions
Cejkova_2012_PLoS.Negl.Trop.Dis_6_E1471Whole genome sequences of three Treponema pallidum ssp. pertenue strains: yaws and syphilis treponemes differ in less than 0.2% of the genome sequence
Cerejeira_2012_J.Am.Geriatr.Soc_60_669The cholinergic system and inflammation: common pathways in delirium pathophysiology
Cesa_2012_Mol.Pharmacol_81_239Specificity determinants of allosteric modulation in the neuronal nicotinic acetylcholine receptor: a fine line between inhibition and potentiation
Cesarino_2012_Food.Chem_135_873Electrochemical detection of carbamate pesticides in fruit and vegetables with a biosensor based on acetylcholinesterase immobilised on a composite of polyaniline-carbon nanotubes
Chai_2012_J.Bacteriol_194_6693Draft genome sequence of high-melanin-yielding Aeromonas media strain WS
Chaiyana_2012_Phytomedicine_19_836Inhibition of cholinesterase by essential oil from food plant
Chakkalakal_2012_Genesis_50_50Mouse transgenic lines that selectively label Type I, Type IIA, and Types IIX+B skeletal muscle fibers
Chakraborty_2012_PLoS.One_7_e32011A measure of the promiscuity of proteins and characteristics of residues in the vicinity of the catalytic site that regulate promiscuity
Chan_2012_J.Bacteriol_194_5485Genome sequence of Citrobacter sp. strain A1, a dye-degrading bacterium
Chan_2012_J.Bacteriol_194_549Whole-genome sequence of the emerging pathogen Mycobacterium abscessus strain 47J26
Chan_2012_J.Bacteriol_194_5716Genome sequence of Enterococcus sp. strain C1, an azo dye decolorizer
Chan_2012_Neurosci.Lett_523_71N-linked glycosylation of proline-rich membrane anchor (PRiMA) is not required for assembly and trafficking of globular tetrameric acetylcholinesterase
Chan_2012_Pediatr.Neurol_47_137Neuromuscular junction acetylcholinesterase deficiency responsive to albuterol
Chang_2012_Acta.Biomater_8_1380Carboxylesterase expression in human dental pulp cells: role in regulation of BisGMA-induced prostanoid production and cytotoxicity
Chang_2012_Angew.Chem.Int.Ed.Engl_51_966An activity-based imaging probe for the integral membrane hydrolase KIAA1363
Chang_2012_Chem.Biol_19_579Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates
Chang_2012_FEBS.Lett_586_3111Agrin induces association of Chrna1 mRNA and nicotinic acetylcholine receptor in C2C12 myotubes
Chang_2012_J.Bacteriol_194_5120Genome sequence of n-alkane-degrading Hydrocarboniphaga effusa strain AP103T (ATCC BAA-332T)
Chang_2012_J.Med.Entomol_49_631Contact and fumigant toxicity of Cyperus rotundus steam distillate constituents and related compounds to insecticide-susceptible and -resistant Blattella germanica
Chao_2012_Bioorg.Med.Chem.Lett_22_6498Design, synthesis and pharmacological evaluation of novel tacrine-caffeic acid hybrids as multi-targeted compounds against Alzheimer's disease
Charbonneau_2012_Indian.J.Microbiol_52_41Identification of thermophilic bacterial strains producing thermotolerant hydrolytic enzymes from manure compost
Charbonneau_2012_Protein.Pept.Lett_19_264N-terminal purification tag alters thermal stability of the carboxylesterase EstGtA2 from G. thermodenitrificans by impairing reversibility of thermal unfolding
Charette_2012_J.Bacteriol_194_722Draft genome sequence of the virulent strain 01-B526 of the fish pathogen Aeromonas salmonicida
Charles-Schoeman_2012_Ann.Rheum.Dis_71_1157Cholesterol efflux by high density lipoproteins is impaired in patients with active rheumatoid arthritis
Charradi_2012_Neurochem.Res_37_2004Grape seed and skin extract prevents high-fat diet-induced brain lipotoxicity in rat
Chatterjee_2012_Neurochem.Res_37_759Evaluation of the antipsychotic potential of Panax quinquefolium in ketamine induced experimental psychosis model in mice
Chattopadhyay_2012_Drug.Chem.Toxicol_35_81Hepatoprotective role of vitamin B(12) and folic acid in arsenic intoxicated rats
Chaudhary_2012_Neurosci_225_258An in vitro approach to assess the neurotoxicity of valproic acid-induced oxidative stress in cerebellum and cerebral cortex of young rats
Che_2012_Toxicol.Mech.Methods_22_250Treatment with endotracheal therapeutics after sarin microinstillation inhalation exposure increases blood cholinesterase levels in guinea pigs
Cheevadhanarak_2012_Stand.Genomic.Sci_6_43Draft genome sequence of Arthrospira platensis C1 (PCC9438)
Chen_2012_Am.J.Psychiatry_169_735Interplay of genetic risk factors (CHRNA5-CHRNA3-CHRNB4) and cessation treatments in smoking cessation success
Chen_2012_Anal.Biochem_429_42A thin film electro-acoustic enzyme biosensor allowing the detection of trace organophosphorus pesticides
Chen_2012_Appl.Environ.Microbiol_78_7798Genomic and transcriptomic studies of an RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine)-degrading actinobacterium
Chen_2012_BMC.Genomics_13_S4Whole-genome sequencing and identification of Morganella morganii KT pathogenicity-related genes
Chen_2012_Biochem.Pharmacol_84_864Antioxidant sulforaphane and sensitizer trinitrobenzene sulfonate induce carboxylesterase-1 through a novel element transactivated by nuclear factor-E2 related factor-2
Chen_2012_Biochemistry_51_1297Reaction pathway and free energy profiles for butyrylcholinesterase-catalyzed hydrolysis of acetylthiocholine
Chen_2012_Bioorg.Med.Chem.Lett_22_3181Discovery of a novel acetylcholinesterase inhibitor by structure-based virtual screening techniques
Chen_2012_Bull.Environ.Contam.Toxicol_88_654Imidacloprid affects Pardosa pseudoannulata adults and their unexposed offspring
Chen_2012_Cell.Rep_2_1329Monoacylglycerol lipase is a therapeutic target for Alzheimer's disease
Chen_2012_Clin.Transl.Sci_5_27Bone marrow-derived mesenchymal stem cells up-regulate acetylcholine receptor delta subunit through NRG/ErbB3-mediated mitogen-activated protein kinase pathway
Chen_2012_Drug.Alcohol.Depend_123 Suppl 1_S42Nicotine dependence and comorbid psychiatric disorders: examination of specific genetic variants in the CHRNA5-A3-B4 nicotinic receptor genes
Chen_2012_Environ.Sci.Technol_46_1828Highly sensitive and selective immuno-capture/electrochemical assay of acetylcholinesterase activity in red blood cells: a biomarker of exposure to organophosphorus pesticides and nerve agents
Chen_2012_Environ.Sci.Technol_46_9727Prenatal Transfer of Polybrominated Diphenyl Ethers (PBDEs) Results in Developmental Neurotoxicity in Zebrafish Larvae
Chen_2012_Environ.Toxicol.Chem_31_2338Acute exposure to DE-71: effects on locomotor behavior and developmental neurotoxicity in zebrafish larvae
Chen_2012_J.Appl.Toxicol_32_673Calibration and validation of a physiologically based model for soman intoxication in the rat, marmoset, guinea pig and pig
Chen_2012_J.Bacteriol_194_1837Genome sequence of a serotype b non-JP2 aggregatibacter actinomycetemcomitans strain, ANH9381, from a periodontally healthy individual
Chen_2012_J.Biotechnol_162_183Use of hydrophilic ionic liquids in a two-phase system to improve Mung bean epoxide hydrolases-mediated asymmetric hydrolysis of styrene oxide
Chen_2012_J.Clin.Pharmacol_52_319Pharmacokinetics and pharmacodynamics of AR9281, an inhibitor of soluble epoxide hydrolase, in single- and multiple-dose studies in healthy human subjects
Chen_2012_J.Comp.Neurol_520_434Active zone density is conserved during synaptic growth but impaired in aged mice
Chen_2012_J.Med.Chem_55_4309Tacrine-ferulic acid-nitric oxide (NO) donor trihybrids as potent, multifunctional acetyl- and butyrylcholinesterase inhibitors
Chen_2012_J.Med.Chem_55_5231Tacrine-silibinin codrug shows neuro- and hepatoprotective effects in vitro and pro-cognitive and hepatoprotective effects in vivo
Chen_2012_J.Neurosci_32_16018Drosophila Neuroligin 2 is Required Presynaptically and Postsynaptically for Proper Synaptic Differentiation and Synaptic Transmission
Chen_2012_Metabolism_61_470Small molecule activation of lecithin cholesterol acyltransferase modulates lipoprotein metabolism in mice and hamsters
Chen_2012_Mol.Biol.Cell_23_2680The function of p120 catenin in filopodial growth and synaptic vesicle clustering in neurons
Chen_2012_Mol.Med.Rep_5_1043Computational analysis of novel drugs designed for use as acetylcholinesterase inhibitors and histamine H3 receptor antagonists for Alzheimer's disease by docking, scoring and de novo evolution
Chen_2012_Neurobiol.Aging_33_2721 e3No association of five candidate genetic variants with amyotrophic lateral sclerosis in a Chinese population
Chen_2012_Neurosci.Lett_528_148Hyper-phosphorylation of GSK-3beta: Possible roles in chlorpyrifos-induced behavioral alterations in animal model of depression
Chen_2012_Nicotine.Tob.Res_14_425Dissection of the phenotypic and genotypic associations with nicotinic dependence
Chen_2012_Protein.Expr.Purif_81_18Functional expression of rat neuroligin-1 extracellular fragment by a bi-cistronic baculovirus expression vector
Cheng_2012_Aging.Ment.Health_16_516Under-recognition of dementia in long-term care homes in Hong Kong
Cheng_2012_Comput.Sci.Discov_5_Multi-Scale Continuum Modeling of Biological Processes: From Molecular Electro-Diffusion to Sub-Cellular Signaling Transduction
Cheng_2012_FEBS.J_279_3727Requirement of lid2 for interfacial activation of a family I.3 lipase with unique two lid structures
Cheng_2012_J.Asia.Pac.Entomol_15_142Efficacy of the predator Mallada basalis (Neuroptera: Chrysopidae) on Tetranychus kanzawai and Panonychus citri (Acari: Tetranychidae) at different predator:prey release ratios
Cheng_2012_Phytother.Res_26_1173Extracts of Cordyceps militaris lower blood glucose via the stimulation of cholinergic activation and insulin secretion in normal rats
Cheng_2014_Am.J.Geriatr.Psychiatry_22_63Mental and Physical Activities Delay Cognitive Decline in Older Persons With Dementia
Chepyshko_2012_BMC.Genomics_13_309Multifunctionality and diversity of GDSL esterase/lipase gene family in rice (Oryza sativa L. japonica) genome: new insights from bioinformatics analysis
Chernyavsky_2012_Dermatoendocrinol_4_324Auto/paracrine nicotinergic peptides participate in cutaneous stress response to wounding
Chernyavsky_2012_Wound.Repair.Regen_20_103Novel cholinergic peptides SLURP-1 and -2 regulate epithelialization of cutaneous and oral wounds
Chertemps_2012_BMC.Biol_10_56A carboxylesterase, Esterase-6, modulates sensory physiological and behavioral response dynamics to pheromone in Drosophila
Chertemps_2012_Naturwiss_99_537Characterization of maspardin, responsible for human Mast syndrome, in an insect species and analysis of its evolution in metazoans
Cherubini_2012_J.Am.Med.Dir.Assoc_13_759 e7Underrecognition and undertreatment of dementia in italian nursing homes
Cheung_2012_J.Med.Chem_55_10282Structures of human acetylcholinesterase in complex with pharmacologically important ligands
Chevessier_2012_Neurobiol.Dis_45_851A new mouse model for the slow-channel congenital myasthenic syndrome induced by the AChR epsilonL221F mutation
Chiang_2012_Ecotoxicol.Environ.Saf_86_147Liver ethoxyresorufin-O-deethylase and brain acetylcholinesterase in two freshwater fish species of South America; the effects of seasonal variability on study design for biomonitoring
Chikova_2012_Life.Sci_91_1103New associations of the genetic polymorphisms in nicotinic receptor genes with the risk of lung cancer
Chiorean_2012_Cancer.Chemother.Pharmacol_70_25Phase II and gene expression analysis trial of neoadjuvant capecitabine plus irinotecan followed by capecitabine-based chemoradiotherapy for locally advanced rectal cancer: Hoosier Oncology Group GI03-53
Cho_2012_Bioprocess.Biosyst.Eng_35_227A neutral lipase applicable in biodiesel production from a newly isolated Streptomyces sp. CS326
Cho_2012_Environ.Toxicol.Pharmacol_33_1Minimum effective drug concentrations of a transdermal patch system containing procyclidine and physostigmine for prophylaxis against soman poisoning in rhesus monkeys
Cho_2012_Theor.Appl.Genet_125_467Construction of a high-resolution linkage map of Rfd1, a restorer-of-fertility locus for cytoplasmic male sterility conferred by DCGMS cytoplasm in radish (Raphanus sativus L.) using synteny between radish and Arabidopsis genomes
Choi_2012_Eur.J.Cancer_48_129Human adipose tissue-derived mesenchymal stem cells: characteristics and therapeutic potential as cellular vehicles for prodrug gene therapy against brainstem gliomas
Choi_2012_J.Bacteriol_194_2756Draft genome sequence of Mycobacterium abscessus subsp. bolletii BD(T)
Choi_2012_J.Bacteriol_194_531Complete genome sequence of the rice pathogen Pantoea ananatis strain PA13
Choi_2012_J.Phys.Chem.B_116_10387Specific and Cooperative Interactions between Oximes and PAMAM Dendrimers As Demonstrated by (1)H NMR Study
Choi_2012_J.Sci.Food.Agric_92_870Lipase-catalysed production of triacylglycerols enriched in pinolenic acid at the sn-2 position from pine nut oil
Chon_2012_PLoS.One_7_e43962Over-expression of monoacylglycerol lipase (MGL) in small intestine alters endocannabinoid levels and whole body energy balance, resulting in obesity
Chong_2012_J.Bacteriol_194_6366Heavy-metal resistance of a France vineyard soil bacterium, Pseudomonas mendocina strain S5.2, revealed by whole-genome sequencing
Chong_2012_Korean.J.Anesthesiol_62_166Midazolam protects B35 neuroblastoma cells through Akt-phosphorylation in reactive oxygen species derived cellular injury
Chong_2012_Sensors.(Basel)_12_4846Characterization of quorum sensing and quorum quenching soil bacteria isolated from Malaysian tropical montane forest
Choo_2012_J.Bacteriol_194_3278Genome sequence of the Mycobacterium abscessus strain M93
Chou_2012_Gene_511_364Sequence of Leptospira santarosai serovar Shermani genome and prediction of virulence-associated genes
Chouhan_2012_J.Neurosci_32_1233Cytosolic calcium coordinates mitochondrial energy metabolism with presynaptic activity
Chow_2012_PLoS.One_7_e47665The metagenome-derived enzymes LipS and LipT increase the diversity of known lipases
Chroni_2012_J.Neurol.Sci_316_150Neurophysiological characteristics of MuSK antibody positive Myasthenia Gravis mice: focal denervation and hypersensitivity to acetylcholinesterase inhibitors
Chtourou_2012_Neurochem.Res_37_469Improvement of cerebellum redox states and cholinergic functions contribute to the beneficial effects of silymarin against manganese-induced neurotoxicity
Chu_2012_Hong.Kong.Med.J_18_228Alzheimer's disease: early diagnosis and treatment
Chugani_2012_Proc.Natl.Acad.Sci.U.S.A_109_E2823Strain-dependent diversity in the Pseudomonas aeruginosa quorum-sensing regulon
Chui_2012_Mol.Neurodegener_7 Suppl 1_O9Implication of lipid metabolism disturbance and Alzheimer's disease: focus on the lipoprotein lipase plays an important role in learning and memory function PMCID: PMC3287633
Chun_2012_J.Bacteriol_194_4116Complete genome sequence of Bacillus anthracis H9401, an isolate from a Korean patient with anthrax
Ciepluch_2012_Int.J.Biol.Macromol_54C_119Effect of viologen-phosphorus dendrimers on acetylcholinesterase and butyrylcholinesterase activities
Ciesla_2012_World.J.Gastroenterol_18_4156Intrahepatic expression of genes related to metabotropic receptors in chronic hepatitis
Cihil_2012_J.Biol.Chem_287_15087Disabled-2 protein facilitates assembly polypeptide-2-independent recruitment of cystic fibrosis transmembrane conductance regulator to endocytic vesicles in polarized human airway epithelial cells
Cirillo_2012_Oral.Dis_18_442Urban legends: pemphigus vulgaris
Ciro_2012_Curr.Alzheimer.Res_9_138Biochemical differentiation of cholinesterases from normal and Alzheimer's disease cortex
Cisneros_2012_J.Med.Chem_55_824Structure-activity relationship of a new series of reversible dual monoacylglycerol lipase/fatty acid amide hydrolase inhibitors
Cisse_2012_MBio_4_e00428De novo assembly of the Pneumocystis jirovecii genome from a single bronchoalveolar lavage fluid specimen from a patient
Clancy_2012_J.Bacteriol_194_2402Draft genome sequences of Helicobacter pylori strains 17874 and P79
Clarke_2012_Front.Mol.Neurosci_5_12Presynaptic Active Zone Density during Development and Synaptic Plasticity
Clement_2012_Neurosci.Res_72_79Acetylcholinesterase activity in the brain of dystonia musculorum (Dst(dt-J)) mutant mice
Clemente_2012_J.Biomol.Screen_17_629Screening and characterization of human monoglyceride lipase active site inhibitors using orthogonal binding and functional assays
Cocelli_2012_Arch.Gynecol.Obstet_286_43Pseudocholinesterase in gestational diabetes: positive correlation with LDL and negative correlation with triglyceride
Codocedo_2012_PLoS.One_7_e47073SIRT1 regulates dendritic development in hippocampal neurons
Coelho_2012_Audiol.Neurootol_17_179Reduction of tinnitus severity by the centrally acting muscle relaxant cyclobenzaprine: an open-label pilot study
Cogun_2012_J.Biochem.Mol.Toxicol_26_117Protective effect of selenium against mercury-induced toxicity on hematological and biochemical parameters of Oreochromis niloticus
Cohen_2012_J.Exp.Biol_215_3639Locomotion analysis identifies roles of mechanosensory neurons in governing locomotion dynamics of C. elegans
Cohen_2012_J.Lipids_2012_762560Increased Levels of Human Carotid Lesion Linoleic Acid Hydroperoxide in Symptomatic and Asymptomatic Patients Is Inversely Correlated with Serum HDL and Paraoxonase 1 Activity
Cohen_2012_Neurosci_200_31Nicotinic cholinergic mechanisms causing elevated dopamine release and abnormal locomotor behavior
Coin_2012_Aging.Clin.Exp.Res_24_14Effects of 21 months of cholinesterase inhibitors on cognitive and functional decline in demented patients
Cole_2012_Neurotoxicol.Teratol_34_311Neurobehavioral assessment of mice following repeated postnatal exposure to chlorpyrifos-oxon
Collins-Praino_2012_Behav.Brain.Res_234_129Extracellular GABA in globus pallidus increases during the induction of oral tremor by haloperidol but not by muscarinic receptor stimulation
Colloca_2012_PLoS.One_7_e46669Inappropriate drugs in elderly patients with severe cognitive impairment: results from the shelter study
Colquhoun_2012_J.Gen.Physiol_140_599Perspectives on: conformational coupling in ion channels: allosteric coupling in ligand-gated ion channels
Cometa_2012_Fitoterapia_83_476New cholinesterase inhibiting bisbenzylisoquinoline alkaloids from Abuta grandifolia
Comim_2012_Neurosci.Lett_523_104Effects of experimental cerebral malaria in memory, brain-derived neurotrophic factor and acetylcholinesterase activity [correction for acitivity] in the hippocampus of survivor mice
Conca_2012_J.Clin.Lipidol_6_244Novel missense variants in LCAT and APOB genes in an Italian kindred with familial lecithin:cholesterol acyltransferase deficiency and hypobetalipoproteinemia
Connelly_2012_J.Histochem.Cytochem_60_694Endothelial lipase is localized to follicular epithelial cells in the thyroid gland and is moderately expressed in adipocytes
Constantinou_2012_J.Chromatogr.Sci_50_228Separation of acetylcholinesterase inhibitors using polymeric surfactants in polyelectrolyte multilayer coatings
Copeland_2012_Stand.Genomic.Sci_6_21Complete genome sequence of the aerobic, heterotroph Marinithermus hydrothermalis type strain (T1(T)) from a deep-sea hydrothermal vent chimney
Coppin_2012_Insect.Biochem.Mol.Biol_42_343Testing the evolvability of an insect carboxylesterase for the detoxification of synthetic pyrethroid insecticides
Corbel_2012_BMC.Biol_10_86Correction: Evidence for inhibition of cholinesterases in insect and mammalian nervous systems by the insect repellent deet
Cornillot_2012_Nucleic.Acids.Res_40_9102Sequencing of the smallest Apicomplexan genome from the human pathogen Babesia microti
Corsetti_2012_Life.Sci_91_783The mechanisms and possible sites of acetylcholine release during chick primary sensory neuron differentiation
Cosgrove_2012_Arch.Gen.Psychiatry_69_418Sex differences in availability of beta2*-nicotinic acetylcholine receptors in recently abstinent tobacco smokers
Costa_2012_An.Acad.Bras.Cienc_84_1105Cholinesterase as inflammatory markers in a experimental infection by Trypanosoma evansi in rabbits
Costa_2012_Cell.Mol.Neurobiol_32_633Anticonvulsant and antioxidant effects of cyano-carvone and its action on acetylcholinesterase activity in mice hippocampus
Costante_2012_Toxicol.In.Vitro_26_182Hydrolysis potential of recombinant human skin and kidney prolidase against diisopropylfluorophosphate and sarin by in vitro analysis
Counotte_2012_FASEB.J_26_1810Adolescent nicotine exposure transiently increases high-affinity nicotinic receptors and modulates inhibitory synaptic transmission in rat medial prefrontal cortex
Counotte_2012_Front.Pharmacol_3_180The Yin and Yang of Nicotine: Harmful during Development, Beneficial in Adult Patient Populations
Cowden_2012_Reprod.Toxicol_33_165Developmental exposure to valproate and ethanol alters locomotor activity and retino-tectal projection area in zebrafish embryos
Cozanitis_2012_Anaesthesiol.Intensive.Ther_44_76Effect on cognition of galanthamine administered for neuromuscular block reversal in octogenarians undergoing cataract surgery
Crane_2012_Toxicology_293_115Effect of CYP2B6*6 and CYP2C19*2 genotype on chlorpyrifos metabolism
Cravo_2012_Mar.Environ.Res_75_23A multibiomarker approach in the clam Ruditapes decussatus to assess the impact of pollution in the Ria Formosa lagoon, South Coast of Portugal
Cresswell_2012_Science_337_1453; author reply 1453Comment on A common pesticide decreases foraging success and survival in honey bees
Criado_2012_J.Neurochem_123_504Expression and functional properties of alpha7 acetylcholine nicotinic receptors are modified in the presence of other receptor subunits
Crow_2012_Biochem.Pharmacol_84_1215Covalent inhibition of recombinant human carboxylesterase 1 and 2 and monoacylglycerol lipase by the carbamates JZL184 and URB597
Crow_2012_Toxicol.Appl.Pharmacol_258_145Inhibition of recombinant human carboxylesterase 1 and 2 and monoacylglycerol lipase by chlorpyrifos oxon, paraoxon and methyl paraoxon
Cruz_2012_J.Environ.Manage_95 Suppl_S256Screening for thermotolerant ligninolytic fungi with laccase, lipase, and protease activity isolated in Mexico
Cserhati_2012_J.Bacteriol_194_2109De novo genome project of Cupriavidus basilensis OR16
Cuartero_2012_Anal.Biochem_421_208Assay of acetylcholinesterase activity by potentiometric monitoring of acetylcholine
Cucuianu_2012_Rom.J.Intern.Med_50_107Thrombotic tendency in diabetes mellitus. Revisiting and revising a study initiated 30 years ago
Cuddy_2012_J.Neurosci_32_5573Peroxynitrite donor SIN-1 alters high-affinity choline transporter activity by modifying its intracellular trafficking
Cuello_2012_Neurochem.Res_37_1256Gangliosides, NGF, brain aging and disease: a mini-review with personal reflections
Cui_2012_Addict.Behav_37_885Differential cigarette-related startle cue reactivity among light, moderate, and heavy smokers
Cui_2012_Extremophiles_16_619High level expression and characterization of a thermostable lysophospholipase from Thermococcus kodakarensis KOD1
Cui_2012_Protein.J_31_432High yield recombinant expression, characterization and homology modeling of two types of cis-epoxysuccinic acid hydrolases
Culzoni_2012_Anal.Chim.Acta_740_27High-performance liquid chromatography with fast-scanning fluorescence detection and multivariate curve resolution for the efficient determination of galantamine and its main metabolites in serum
Cumino_2012_Parasitol.Int_61_579Echinococcus granulosus tegumental enzymes as in vitro markers of pharmacological damage: a biochemical and molecular approach
Curtin_2012_PLoS.ONE_7_E33840De-novo assembly and analysis of the heterozygous triploid genome of the wine spoilage yeast Dekkera bruxellensis AWRI1499
Curtis_2012_J.Invest.Dermatol_132_28Cholinergic regulation of keratinocyte innate immunity and permeability barrier integrity: new perspectives in epidermal immunity and disease
Curtis_2012_Life.Sci_91_1070Nicotinic acetylcholine receptor stimulation impairs epidermal permeability barrier function and recovery and modulates cornified envelope proteins
Curtis_2012_Nature_492_59Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs
Curto_2012_Mol.Phylogenet.Evol_63_758Development of phylogenetic markers from single-copy nuclear genes for multi locus, species level analyses in the mint family (Lamiaceae)
Cuthbertson_2012_Biomed.Chromatogr_26_1191Validation of a microscale extraction and high-throughput UHPLC-QTOF-MS analysis method for huperzine A in Huperzia
Cymes_2012_Nat.Chem.Biol_8_975The unanticipated complexity of the selectivity-filter glutamates of nicotinic receptors
Czajkowski_2012_J.Bacteriol_194_6999Draft genome sequence of the biocontrol strain Serratia plymuthica A30, isolated from rotting potato tuber tissue
Czajkowski_2012_Plant.Pathol_61_169Characterization of bacterial isolates from rotting potato tuber tissue showing antagonism to Dickeya sp. biovar 3 in vitro and in planta
Czernik_2012_Autoimmunity_45_111Intravenous immunoglobulin in the treatment of autoimmune bullous dermatoses: an update
D'Agostino_2012_Pharmacol.Res_65_129Purinergic P2X3 heteroreceptors enhance parasympathetic motor drive in isolated porcine detrusor, a reliable model for development of P2X selective blockers for detrusor hyperactivity
D'Hont_2012_Nature_488_213The banana (Musa acuminata) genome and the evolution of monocotyledonous plants
D'Souza_2012_J.Neurosci_32_3261Nicotinic receptor-mediated filtering of mitral cell responses to olfactory nerve inputs involves the alpha3beta4 subtype
D'Souza_2012_Neuropharmacol_62_1564Schizophrenia and tobacco smoking comorbidity: nAChR agonists in the treatment of schizophrenia-associated cognitive deficits
Daborn_2012_Insect.Biochem.Mol.Biol_42_918Using Drosophila melanogaster to validate metabolism-based insecticide resistance from insect pests
Dakwar_2012_J.Control.Release_160_315Delivery of proteins to the brain by bolaamphiphilic nano-sized vesicles
Dalio_2012_Biochem.Biophys.Res.Commun_419_724Acute cocaine treatment increases thimet oligopeptidase in the striatum of rat brain
Dallal_2012_Can.J.Microbiol_58_605Factors governing the regulation of Sclerotinia sclerotiorum cutinase A and polygalacturonase 1 during different stages of infection
Dallanoce_2012_Bioorg.Med.Chem.Lett_22_829Synthesis and binding affinity at alpha4beta2 and alpha7 nicotinic acetylcholine receptors of new analogs of epibatidine and epiboxidine containing the 7-azabicyclo[2.2.1]hept-2-ene ring system
Dallanoce_2012_Chirality_24_543The enantiomers of epiboxidine and of two related analogs: synthesis and estimation of their binding affinity at alpha4beta2 and alpha7 neuronal nicotinic acetylcholine receptors
Dam_2012_J.Bacteriol_194_6008Complete genome sequence of Methylocystis sp. strain SC2, an aerobic methanotroph with high-affinity methane oxidation potential
Damms-Machado_2012_Obes.Surg_22_881Pre- and postoperative nutritional deficiencies in obese patients undergoing laparoscopic sleeve gastrectomy
Darby_2012_Genome.Res_22_2467Analysis of gene expression from the Wolbachia genome of a filarial nematode supports both metabolic and defensive roles within the symbiosis
Darras_2012_ACS.Med.Chem.Lett_3_914Neuroprotective Tri- and Tetracyclic BChE Inhibitors Releasing Reversible Inhibitors upon Carbamate Transfer
Darreh-Shori_2012_J.Alzheimers.Dis_28_443Apolipoprotein epsilon4 modulates phenotype of butyrylcholinesterase in CSF of patients with Alzheimer's disease
Darvesh_2012_J.Neuropathol.Exp.Neurol_71_2Butyrylcholinesterase is associated with beta-amyloid plaques in the transgenic APPSWE/PSEN1dE9 mouse model of Alzheimer disease
Das_2012_Ann.Hepatol_11_409Acetylcholinesterase and butyrylcholinesterase as markers of low-grade systemic inflammation
Davidson_2012_Alzheimers.Res.Ther_4_51Plasma lipoprotein-associated phospholipase A2 activity in Alzheimer's disease, amnestic mild cognitive impairment, and cognitively healthy elderly subjects: a cross-sectional study
Davies_2012_J.Lipid.Res_53_2690Assessing mechanisms of GPIHBP1 and lipoprotein lipase movement across endothelial cells
Davison_2012_Proc.Natl.Acad.Sci.U.S.A_109_7642Genetic, molecular, and biochemical basis of fungal tropolone biosynthesis
De Bona_2012_Clin.Biochem_45_1081Lymphocytic enzymes and lipid peroxidation in patients with metabolic syndrome
De Cesco_2012_J.Med.Chem_55_6306Virtual screening and computational optimization for the discovery of covalent prolyl oligopeptidase inhibitors with activity in human cells
De Jaco_2012_Febs.J_279_4293Congenital hypothyroidism mutations affect common folding and trafficking in the alpha/beta-hydrolase fold proteins
De Jaco_2012_Protein.Pept.Lett_19_173Processing of cholinesterase-like alpha/beta-hydrolase fold proteins: alterations associated with congenital disorders
De La Garza_2012_Prog.Neuropsychopharmacol.Biol.Psychiatry_37_141Rivastigmine reduces Likely to use methamphetamine in methamphetamine-dependent volunteers
De Maayer_2012_J.Bacteriol_194_1615Complete genome sequence of clinical isolate Pantoea ananatis LMG 5342
De Santi_2012_Biotechnol.Prog_28_946Thermal stabilization of psychrophilic enzymes: a case study of the cold-active hormone-sensitive lipase from Psychrobacter sp. TA144
Dean_2012_J.Neurosci_32_5398Distinct subsets of Syt-IV/BDNF vesicles are sorted to axons versus dendrites and recruited to synapses by activity
Deb_2012_Mol.Divers_16_803Molecular docking and receptor-specific 3D-QSAR studies of acetylcholinesterase inhibitors
Decker_2012_J.Lipid.Res_53_2038EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxides
Dedaev_2012_Zh.Nevrol.Psikhiatr.Im.S.S.Korsakova_112_32[The use of the QMGS for quantitative assessment of the severity of movement disorders in patients with myasthenia]
Dedoni_2012_J.Neurochem_122_58Type I interferons impair BDNF-induced cell signaling and neurotrophic activity in differentiated human SH-SY5Y neuroblastoma cells and mouse primary cortical neurons
Deive_2012_Bioprocess.Biosyst.Eng_35_931A process for extracellular thermostable lipase production by a novel Bacillus thermoamylovorans strain
Del Monte-Martinez_2012_Methods.Mol.Biol_861_343Rational design of immobilized lipases and phospholipases
Del Pozo_2012_Biotechnol.Biofuels_5_73Microbial beta-glucosidases from cow rumen metagenome enhance the saccharification of lignocellulose in combination with commercial cellulase cocktail
Delaux_2012_New.Phytol_195_857Origin of strigolactones in the green lineage
Delay_2012_J.Insect.Physiol_58_1626Transcriptome analysis of the salivary glands of potato leafhopper, Empoasca fabae
Della Torre_2012_Mar.Environ.Res_76_48Modulation of CYP1A and genotoxic effects in European seabass (Dicentrarchus labrax) exposed to weathered oil: a mesocosm study
Delorme_2012_PLoS.One_7_e46493MmPPOX inhibits Mycobacterium tuberculosis lipolytic enzymes belonging to the hormone-sensitive lipase family and alters mycobacterial growth
Demirkan_2012_PLoS.Genet_8_e1002490Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations
Dencker_2012_ACS.Chem.Neurosci_3_80Muscarinic Acetylcholine Receptor Subtypes as Potential Drug Targets for the Treatment of Schizophrenia, Drug Abuse and Parkinson's Disease
Dencker_2012_Psychopharmacology.(Berl)_224_277An allosteric enhancer of M(4) muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaine
Deng_2012_Anal.Chem_84_8232Probing biochemical mechanisms of action of muscarinic M3 receptor antagonists with label-free whole cell assays
Deng_2012_J.Cell.Biochem_113_1087Ins and outs of Mycobacterium tuberculosis PPE family in pathogenesis and implications for novel measures against tuberculosis
Depboylu_2012_J.Neuropathol.Exp.Neurol_71_15Lentiviral infection of rhesus macaques causes long-term injury to cortical and hippocampal projections of prostaglandin-expressing cholinergic basal forebrain neurons
Desnues_2012_Proc.Natl.Acad.Sci.U.S.A_109_18078Provirophages and transpovirons as the diverse mobilome of giant viruses
Devarajan_2012_Mol.Genet.Metab_107_416Macrophage paraoxonase 2 regulates calcium homeostasis and cell survival under endoplasmic reticulum stress conditions and is sufficient to prevent the development of aggravated atherosclerosis in paraoxonase 2 deficiency/apoE-/- mice on a Western diet
Dey_2012_Genetics_191_1257Global population genetic structure of Caenorhabditis remanei reveals incipient speciation
Dhananjayan_2012_Indian.J.Occup.Environ.Med_16_127Assessment of acetylcholinesterase and butyrylcholinesterase activities in blood plasma of agriculture workers
Dhawan_2012_Life.Sci_91_1038Cholinergic signalling in gut immunity
Dhingra_2012_Adv.Pharmacol.Sci_2012_357368Memory-enhancing activity of palmatine in mice using elevated plus maze and morris water maze
Di Giacopo_2012_Mov.Disord_27_559Rivastigmine as alternative treatment for refractory REM behavior disorder in Parkinson's disease
Diehl-Schmid_2012_Alzheimer.Dis.Assoc.Disord_26_166Health care utilization in frontotemporal lobar degeneration
Diez-Torrubia_2012_ChemMedChem_7_618Dipeptidyl peptidase IV (DPPIV/CD26)-based prodrugs of hydroxy-containing drugs
Digby_2012_J.Neurosci_32_8532Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal models
Dimitriadis_2012_Mar.Environ.Res_73_70Monitoring the biochemical and cellular responses of marine bivalves during thermal stress by using biomarkers
Dimitrijevic_2012_Bioresour.Technol_107_358One-step, inexpensive high yield strategy for Candida antarctica lipase A isolation using hydroxyapatite
Dimov_2012_Acta.Biochim.Pol_59_313Correlation between butyrylcholinesterase variants and sensitivity to soman toxicity
Dinakaran_2012_J.Bacteriol_194_6615Genome sequence of Staphylococcus arlettae strain CVD059, isolated from the blood of a cardiovascular disease patient
Dinamarca_2012_Front.Physiol_3_464Postsynaptic Receptors for Amyloid-beta Oligomers as Mediators of Neuronal Damage in Alzheimer's Disease
Ding_2012_Biodegradation_23_127Study on the enzymatic degradation of PBS and its alcohol acid modified copolymer
Ding_2012_Mol.Biol.Rep_39_669A novel single nucleotide polymorphism in exon 7 of LPL gene and its association with carcass traits and visceral fat deposition in yak (Bos grunniens) steers
Ding_2012_OMICS_16_263NDRG4 is downregulated in glioblastoma and inhibits cell proliferation
Diribarne_2012_PLoS.One_7_e30073LIPH expression in skin and hair follicles of normal coat and Rex rabbits
Divisova_2012_J.Peripher.Nerv.Syst_17_341Prediabetes/early diabetes-associated neuropathy predominantly involves sensory small fibres
Djukic_2012_J.Bacteriol_194_6365Genome sequence of Paenibacillus alvei DSM 29, a secondary invader during European foulbrood outbreaks
Dominguez-Renedo_2012_Sci.Total.Environ_426_346Screen-printed acetylcholinesterase-based biosensors for inhibitive determination of permethrin
Donato_2012_Angew.Chem.Int.Ed.Engl_51_1840Water-soluble, donor-acceptor biphenyl derivatives in the 2-(o-nitrophenyl)propyl series: highly efficient two-photon uncaging of the neurotransmitter gamma-aminobutyric acid at lambda = 800 nm
Dong_2012_Sheng.Wu.Gong.Cheng.Xue.Bao_28_557[Expression and molecular evolution of recombinant acetylcholinesterase for detection of pesticide residues: a review]
Doody_2012_Curr.Alzheimer.Res_9_773Reviewing the role of donepezil in the treatment of Alzheimer's disease
Dos_2012_Mol.Biol.Rep_39_10157Prognostic significance of NDRG1 expression in oral and oropharyngeal squamous cell carcinoma
Dou_2012_J.Environ.Sci.(China)_24_956A screen-printed, amperometric biosensor for the determination of organophosphorus pesticides in water samples
Dowling_2012_Dis.Model.Mech_5_852Myotubular myopathy and the neuromuscular junction: a novel therapeutic approach from mouse models
Drager_2012_Eur.Heart.J_33_783Intermittent hypoxia inhibits clearance of triglyceride-rich lipoproteins and inactivates adipose lipoprotein lipase in a mouse model of sleep apnoea
Drenan_2012_Pharmacol.Rev_64_869Insights into the neurobiology of the nicotinic cholinergic system and nicotine addiction from mice expressing nicotinic receptors harboring gain-of-function mutations
Dressel_2012_Case.Rep.Oncol_5_47Irinotecan-induced dysarthria
Drienovska_2012_Appl.Environ.Microbiol_78_4995Biochemical characterization of a novel haloalkane dehalogenase from a cold-adapted bacterium
Du_2012_Anal.Chem_84_1380Integrated lateral flow test strip with electrochemical sensor for quantification of phosphorylated cholinesterase: biomarker of exposure to organophosphorus agents
Du_2012_Exp.Ther.Med_3_818Sodium aescinate ameliorates liver injury induced by methyl parathion in rats
Du_2012_Mol.Med.Rep_6_100Chrysin attenuates allergic airway inflammation by modulating the transcription factors T-bet and GATA-3 in mice
Du_2012_PLoS.One_7_e31045Identification of lipases involved in PBAN stimulated pheromone production in Bombyx mori using the DGE and RNAi approaches
Du_2012_Virology_424_18Glycosyl-phosphatidylinositol (GPI)-anchored membrane association of the porcine reproductive and respiratory syndrome virus GP4 glycoprotein and its co-localization with CD163 in lipid rafts
Du_2012_Zhonghua.Yi.Xue.Za.Zhi_92_86[Effects of soluble epoxide hydrolase inhibitors on the expression of fatty acid synthase in peripheral blood mononuclear cell of patients and inflammatory response with acute coronary syndrome]
Duan_2012_J.Biotechnol_159_44Rational synthesis of 1,3-diolein by enzymatic esterification
Duan_2012_Toxicol.Appl.Pharmacol_260_17Development of monoclonal antibodies to human microsomal epoxide hydrolase and analysis of preneoplastic antigen-like molecules
Duarte_2012_Toxicol.Lett_213_142Follow up studies on the respiratory pattern and total cholinesterase activities in dichlorvos-poisoned rats
Dubois_2012_Mov.Disord_27_1230Donepezil in Parkinson's disease dementia: a randomized, double-blind efficacy and safety study
Dudai_2012_Annu.Rev.Neurosci_35_227The restless engram: consolidations never end
Dudai_2012_Front.Hum.Neurosci_6_248The cinema-cognition dialogue: a match made in brain
Duez_2012_Biochem.Pharmacol_83_823DPP-4 inhibitors in the treatment of type 2 diabetes
Dufresne_2012_Mol.Pharm_9_1803Lipase is essential for the study of in vitro release kinetics from organogels
Duguid_2012_J.Neurosci_32_11132Tonic inhibition enhances fidelity of sensory information transmission in the cerebellar cortex
Dulin_2012_Ecotoxicol.Environ.Saf_79_13Interpretation of honeybees contact toxicity associated to acetylcholinesterase inhibitors
Dupont_2012_ISME.J_6_1186Genomic insights to SAR86, an abundant and uncultivated marine bacterial lineage
Dupuis_2012_Neurosci.Biobehav.Rev_36_1553Insights from honeybee (Apis mellifera) and fly (Drosophila melanogaster) nicotinic acetylcholine receptors: from genes to behavioral functions
Duquesne_2012_J.Bacteriol_194_3559Draft genome sequence of the purple photosynthetic bacterium Phaeospirillum molischianum DSM120, a particularly versatile bacterium
Duquesne_2012_Methods.Mol.Biol_861_301The yeast Yarrowia lipolytica as a generic tool for molecular evolution of enzymes
Durand_2012_Clin.Microbiol.Infect_18_338Insecticide resistance in head lice: clinical, parasitological and genetic aspects
Durand_2012_Commun.Integr.Biol_5_284Antennal carboxylesterases in a moth, structural and functional diversity
Durrant_2012_Front.Mol.Neurosci_5_73Serum cholinesterases are differentially regulated in normal and dystrophin-deficient mutant mice
Duysen_2012_Chem.Biol.Interact_195_189Differential sensitivity of plasma carboxylesterase-null mice to parathion, chlorpyrifos and chlorpyrifos oxon, but not to diazinon, dichlorvos, diisopropylfluorophosphate, cresyl saligenin phosphate, cyclosarin thiocholine, tabun thiocholine, and carbofuran
Dzul-Caamal_2012_Ecotoxicol.Environ.Saf_84_199Implications of cytochrome 450 isoenzymes, aryl-esterase and oxonase activity in the inhibition of the acetylcholinesterase of Chirostoma jordani treated with phosphorothionate pesticides
Earl_2012_J.Bacteriol_194_2378Whole-genome sequences of Bacillus subtilis and close relatives
Eberhart_2012_Chromosome.Res_20_849Reliable detection of epigenetic histone marks and nuclear proteins in tissue cryosections
Eckle_2012_Med.Sci.Monit_18_CS91Recovery of residual curarization after red blood cell transfusion
Eddleston_2012_Toxicology_294_94A role for solvents in the toxicity of agricultural organophosphorus pesticides
Eglen_2012_Handb.Exp.Pharmacol_208_3Overview of muscarinic receptor subtypes
Ehlert_2012_Handb.Exp.Pharmacol_208_343Muscarinic agonists and antagonists: effects on gastrointestinal function
Eichenbaum_2012_J.Pharm.Sci_101_1242Use of enzyme inhibitors to evaluate the conversion pathways of ester and amide prodrugs: a case study example with the prodrug ceftobiprole medocaril
Eisenberger_2012_Orphanet.J.Rare.Dis_7_59Targeted next-generation sequencing identifies a homozygous nonsense mutation in ABHD12, the gene underlying PHARC, in a family clinically diagnosed with Usher syndrome type 3
Eklof-Ljunggren_2012_Proc.Natl.Acad.Sci.U.S.A_109_5511Origin of excitation underlying locomotion in the spinal circuit of zebrafish
El Hassani_2012_Eur.J.Neurosci_36_2409Identification, localization and function of glutamate-gated chloride channel receptors in the honeybee brain
El Omri_2012_Brain.Res_1437_16Luteolin enhances cholinergic activities in PC12 cells through ERK1/2 and PI3K/Akt pathways
El-Maghraby_2012_Asian.Pac.J.Trop.Biomed_2_558Toxicological studies for some agricultural waste extracts on mosquito larvae and experimental animals
ElMazoudy_2012_J.Hazard.Mater_209-210_111Endocrine-disrupting and cytotoxic potential of anticholinesterase insecticide, diazinon in reproductive toxicity of male mice
Elias_2012_J.Biol.Chem_287_11Divergence and convergence in enzyme evolution: parallel evolution of paraoxonases from quorum-quenching lactonases
Ellegren_2012_Nature_491_756The genomic landscape of species divergence in Ficedula flycatchers
Ellison_2012_Drug.Metab.Dispos_40_1Human hepatic cytochrome P450-specific metabolism of the organophosphorus pesticides methyl parathion and diazinon
Ellison_2012_Toxicol.Appl.Pharmacol_265_308PON1 status does not influence cholinesterase activity in Egyptian agricultural workers exposed to chlorpyrifos
Elphick_2012_Philos.Trans.R.Soc.Lond.B.Biol.Sci_367_3201The evolution and comparative neurobiology of endocannabinoid signalling
Ely_2012_J.Inorg.Biochem_106_19Phosphate-bound structure of an organophosphate-degrading enzyme from Agrobacterium radiobacter
Ema_2012_Org.Biomol.Chem_10_6299Redesign of enzyme for improving catalytic activity and enantioselectivity toward poor substrates: manipulation of the transition state
Emerick_2012_Chem.Biol.Interact_199_177Mechanisms for consideration for intervention in the development of organophosphorus-induced delayed neuropathy
Emerick_2012_Environ.Toxicol.Chem_31_239Semipreparative enantioseparation of methamidophos by HPLC-UV and preliminary in vitro study of butyrylcholinesterase inhibition
Emerick_2012_Toxicology_292_145Comparative in vitro study of the inhibition of human and hen esterases by methamidophos enantiomers
Emerick_2012_Toxicology_302_88Biochemical, histopathological and clinical evaluation of delayed effects caused by methamidophos isoforms and TOCP in hens: ameliorative effects using control of calcium homeostasis
Engedal_2012_Acta.Neurol.Scand_126_37Two galantamine titration regimens in patients switched from donepezil
Engel_2012_Curr.Neurol.Neurosci.Rep_12_92Congenital myasthenic syndromes in 2012
Engel_2012_Neuromuscul.Disord_22_99Current status of the congenital myasthenic syndromes
Engelter_2012_Eur.Neurol_68_28Frequency and determinants of using pharmacological enhancement in the clinical practice of in-hospital stroke rehabilitation
English_2012_PLoS.ONE_7_E47768Mind the gap: upgrading genomes with Pacific Biosciences RS long-read sequencing technology
Eriksson_2012_J.Pharm.Pharmacol_64_1667In-vitro evaluation of the P-glycoprotein interactions of a series of potentially CNS-active Amaryllidaceae alkaloids
Erlich_2012_Neurobiol.Aging_33_1015 e7Serum paraoxonase activity is associated with variants in the PON gene cluster and risk of Alzheimer disease
Erzengin_2012_Appl.Biochem.Biotechnol_168_1540In vitro inhibition effect of some dihydroxy coumarin compounds on purified human serum paraoxonase 1 (PON1)
Espanol_2012_Eur.J.Pharmacol_683_43Muscarinic regulation of SCA-9 cell proliferation via nitric oxide synthases, arginases and cyclooxygenases. Role of the nuclear translocation factor-kappaB
Espinoza-Valles_2012_J.Bacteriol_194_2104Draft genome sequence of the shrimp pathogen Vibrio harveyi CAIM 1792
Estevan_2012_J.Occup.Environ.Hyg_9_653Characterization and evolution of exposure to volatile organic compounds in the Spanish shoemaking industry over a 5-year period
Estevan_2012_Toxicol.Lett_217_14Chlorpyrifos and its metabolites alter gene expression at non-cytotoxic concentrations in D3 mouse embryonic stem cells under in vitro differentiation: Considerations for embryotoxic risk assessment
Estevez_2012_Arch.Toxicol_86_767Kinetics of inhibition of soluble peripheral nerve esterases by PMSF: a non-stable compound that potentiates the organophosphorus-induced delayed neurotoxicity
Evoli_2012_Ann.N.Y.Acad.Sci_1274_86Management challenges in muscle-specific tyrosine kinase myasthenia gravis
Exley_2012_J.Neurosci_32_2352Striatal alpha5 nicotinic receptor subunit regulates dopamine transmission in dorsal striatum
Ezzaher_2012_Ann.Biol.Clin.(Paris)_70_25[Pseudocholinesterase activity in type 1 bipolar patients]
Fabritz_2012_AMB.Express_2_51A sensitive method for rapid detection of alkyl halides and dehalogenase activity using a multistep enzyme assay
Falchook_2012_Lancet_379_1893Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial
Fale_2012_Food.Chem.Toxicol_50_2656Acetylcholinesterase inhibition, antioxidant activity and toxicity of Peumus boldus water extracts on HeLa and Caco-2 cell lines
Fale_2012_Food.Funct_3_1176Interaction between Plectranthus barbatus herbal tea components and acetylcholinesterase: binding and activity studies
Falfushynska_2012_Environ.Toxicol_27_485Main partitioning criteria for the characterization of the health status in the freshwater mussel Anodonta cygnea from spontaneously polluted area in western ukraine
Falugi_2012_Front.Mol.Neurosci_5_54Early appearance and possible functions of non-neuromuscular cholinesterase activities
Falugi_2012_Mar.Environ.Res_76_114Toxicity of metal oxide nanoparticles in immune cells of the sea urchin
Fan_2012_Eur.J.Cell.Biol_91_265Molecular mechanism and structural basis of interactions of dipeptidyl peptidase IV with adenosine deaminase and human immunodeficiency virus type-1 transcription transactivator
Fan_2012_J.Mol.Catal.B.Enzym_83_29The cloning and characterization of one novel metagenome-derived thermostable esterase acting on N-acylhomoserine lactones
Fan_2012_Methods.Mol.Biol_861_471Lipases as biocatalyst for biodiesel production
Fan_2012_Microb.Cell.Fact_11_33Identification and characterization of a novel thermostable pyrethroid-hydrolyzing enzyme isolated through metagenomic approach
Fan_2012_Pathol.Oncol.Res_18_549Increased NDRG1 expression is associated with advanced T stages and poor vascularization in non-small cell lung cancer
Fan_2012_Zhonghua.Yi.Xue.Za.Zhi_92_2366[Intranasal dosing of nerve growth factor protects brain from poisoning of organophosphorus compounds in rats]
Fang_2012_Chem.Pharm.Bull.(Tokyo)_60_1351Capsofulvesins A-C, Cholinesterase Inhibitors from Capsosiphon fulvescens
Fang_2012_J.Bacteriol_194_6604First genome sequence of a Burkholderia pseudomallei Isolate in China, strain BPC006, obtained from a melioidosis patient in Hainan
Fang_2012_Naunyn.Schmiedebergs.Arch.Pharmacol_385_579FLZ, synthetic squamosamide cyclic derivative, attenuates memory deficit and pathological changes in mice with experimentally induced aging
Faoro_2012_FEMS.Microbiol.Ecol_81_386Characterization of a new Acidobacteria-derived moderately thermostable lipase from a Brazilian Atlantic Forest soil metagenome
Farag_2012_Andrologia_44_116Evaluation of male-mediated reproductive toxic effects of methamidophos in the mouse
Farar_2012_J.Neurochem_122_1065Near-complete adaptation of the PRiMA knockout to the lack of central acetylcholinesterase
Farrimond_2012_BMJ.Open_2_Memantine and cholinesterase inhibitor combination therapy for Alzheimer's disease: a systematic review
Fasano_2012_Mol.Genet.Metab_105_450Lysosomal lipase deficiency: molecular characterization of eleven patients with Wolman or cholesteryl ester storage disease
Faure_2012_Toxicon_60_531Crystallographic characterization of functional sites of crotoxin and ammodytoxin, potent beta-neurotoxins from Viperidae venom
Favara_2012_S.Afr.Med.J_103_40The burden of deliberate self-harm on the critical care unit of a peri-urban referral hospital in the Eastern Cape: A 5-year review of 419 patients
Favero_2012_Proc.Natl.Acad.Sci.U.S.A_109_E1667Spike timing plays a key role in synapse elimination at the neuromuscular junction
Favrot_2012_Expert.Rev.Anti.Infect.Ther_10_1023Targeting the mycobacterial envelope for tuberculosis drug development
Fedorov_2012_J.Neurosci.Methods_206_23A method for bidirectional solution exchange--liquid bullet applications of acetylcholine to alpha7 nicotinic receptors
Fekete_2012_Int.J.Med.Microbiol_302_4DNA sequence analysis of the composite plasmid pTC conferring virulence and antimicrobial resistance for porcine enterotoxigenic Escherichia coli
Feledziak_2012_Recent.Pat.CNS.Drug.Discov_7_49Inhibitors of the endocannabinoid-degrading enzymes, or how to increase endocannabinoid's activity by preventing their hydrolysis
Felline_2012_PLoS.One_7_e38763Subtle effects of biological invasions: cellular and physiological responses of fish eating the exotic pest Caulerpa racemosa
Fendri_2012_Int.J.Biol.Macromol_50_1238A thermoactive uropygial esterase from chicken: purification, characterisation and synthesis of flavour esters
Feng_2012_CNS.Neurosci.Ther_18_974Fluoxetine Induces Hepatic Lipid Accumulation Via Both Promotion of the SREBP1c-Related Lipogenesis and Reduction of Lipolysis in Primary Mouse Hepatocytes
Feng_2012_Chem.Biol.Interact_199_143Metabonomics analysis of urine and plasma from rats given long-term and low-dose dimethoate by ultra-performance liquid chromatography-mass spectrometry
Feng_2012_Chemistry_18_5646Enhancing the efficiency of directed evolution in focused enzyme libraries by the adaptive substituent reordering algorithm
Feng_2012_Int.J.Pharm_423_226Enhancement of nose-to-brain delivery of basic fibroblast growth factor for improving rat memory impairments induced by co-injection of beta-amyloid and ibotenic acid into the bilateral hippocampus
Feng_2012_J.Bacteriol_194_744Complete genome sequence of Salmonella enterica serovar pullorum RKS5078
Feng_2012_Neurol.Sci_33_771A retrospective review of 15 patients with familial myasthenia gravis over a period of 25 years
Fernandes_2012_Eur.J.Med.Chem_55_1Synthesis of new chiral xanthone derivatives acting as nerve conduction blockers in the rat sciatic nerve
Fernandes_2012_Magn.Reson.Chem_50_42413C NMR quantification of mono and diacylglycerols obtained through the solvent-free lipase-catalyzed esterification of saturated fatty acids
Fernandez-Bachiller_2012_J.Med.Chem_55_1303New tacrine-4-oxo-4H-chromene hybrids as multifunctional agents for the treatment of Alzheimer's disease, with cholinergic, antioxidant, and beta-amyloid-reducing properties
Fernandez-Fueyo_2012_Proc.Natl.Acad.Sci.U.S.A_109_5458Comparative genomics of Ceriporiopsis subvermispora and Phanerochaete chrysosporium provide insight into selective ligninolysis
Ferreira_2012_Molecules_17_8955Syntheses of enantiopure aliphatic secondary alcohols and acetates by bioresolution with lipase B from Candida antarctica
Ferreira_2012_Neurochem.Int_61_1370l-Tyrosine administration increases acetylcholinesterase activity in rats
Ferreres_2012_Food.Chem_134_894Bauhinia forficata Link authenticity using flavonoids profile: Relation with their biological properties
Ferretti_2012_Br.J.Dermatol_166_204Correlation between lipoprotein(a) and lipid peroxidation in psoriasis: role of the enzyme paraoxonase-1
Ferretti_2012_Dis.Model.Mech_5_698Altered inflammation, paraoxonase-1 activity and HDL physicochemical properties in obese humans with and without Prader-Willi syndrome
Ferretti_2012_J.Lipids_2012_587479Lipid peroxidation and paraoxonase-1 activity in celiac disease
Ferretti_2012_Life.Sci_91_1134M2 muscarinic receptors inhibit cell proliferation in human glioblastoma cell lines
Ferretti_2012_Nutr.Metab.Cardiovasc.Dis_22_88Effect of dietary lipids on paraoxonase-1 activity and gene expression
Fersini_2012_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_68_923Cloning, expression, purification and preliminary X-ray analysis of a putative metagenome-derived lipase
Fetoui_2012_Hum.Exp.Toxicol_31_1151Synthetic pyrethroid increases lipid and protein oxidation and induces glutathione depletion in the cerebellum of adult rats: Ameliorative effect of vitamin C
Fiedler_2012_Artif.Organs_36_886Randomized controlled pilot study of 2 weeks' treatment with high cutoff membrane for hemodialysis patients with elevated C-reactive protein
Figueiredo_2012_Carbohydr.Res_347_47Facile synthesis of oxo-/thioxopyrimidines and tetrazoles C-C linked to sugars as novel non-toxic antioxidant acetylcholinesterase inhibitors
Filho_2012_Phytother.Res_26_1472Inhibitory Effect of Verbascoside Isolated from Buddleja brasiliensis Jacq. ex Spreng on Prolyl Oligopeptidase Activity
Filippini_2012_J.Bacteriol_194_3555Genome sequence of Fibrella aestuarina BUZ 2(T), a filamentous marine bacterium
Filippini_2012_J.Bacteriol_194_4445Genome sequence of the filamentous bacterium Fibrisoma limi BUZ 3T
Finn_2012_J.Neurosci.Res_90_367Altered glutamate receptor function in the cerebellum of the Ppt1-/- mouse, a murine model of infantile neuronal ceroid lipofuscinosis
Finsterer_2012_J.Neurol.Sci_318_1Hereditary spastic paraplegias with autosomal dominant, recessive, X-linked, or maternal trait of inheritance
Fiorino_2012_Handb.Exp.Pharmacol_208_191Muscarinic pain pharmacology: realizing the promise of novel analgesics by overcoming old challenges
Fisher_2012_J.Neurochem_120 Suppl 1_22Cholinergic modulation of amyloid precursor protein processing with emphasis on M1 muscarinic receptor: perspectives and challenges in treatment of Alzheimer's disease
Fitzgerald_2012_Clin.Epidemiol_4_151Beta blockers, norepinephrine, and cancer: an epidemiological viewpoint
Flaskos_2012_Toxicol.Lett_209_86The developmental neurotoxicity of organophosphorus insecticides: a direct role for the oxon metabolites
Flicker_2012_Med.J.Aust_196_114Memory loss
Flores_2012_Protein.Eng.Des.Sel_25_387Evolution of a new function in an esterase: simple amino acid substitutions enable the activity present in the larger paralog, BioH
Floudas_2012_Science_336_1715The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes
Flowers_2012_Development_139_2416A zebrafish Notum homolog specifically blocks the Wnt/beta-catenin signaling pathway
Foeger_2012_J.Biol.Chem_287_9640Augmentation of Kv4.2-encoded currents by accessory dipeptidyl peptidase 6 and 10 subunits reflects selective cell surface Kv4.2 protein stabilization
Fontanesi_2012_J.Anim.Sci_90_2450Identification and association analysis of several hundred single nucleotide polymorphisms within candidate genes for back fat thickness in Italian Large White pigs using a selective genotyping approach
Fornari_2012_Mol.Biol.Rep_39_4051Transcription profiling of Prss16 (Tssp) can be used to find additional peptidase genes that are candidates for self-peptide generation in the thymus
Forsgren_2012_Life.Sci_91_1043Presence of ChAT mRNA and a very marked alpha7nAChR immunoreaction in the synovial lining layer of the knee joint
Fosbol_2012_J.Am.Geriatr.Soc_60_2283Comparative cardiovascular safety of dementia medications: a cross-national study
Foster_2012_Discov.Med_14_413Emerging approaches for treatment of schizophrenia: modulation of cholinergic signaling
Foster_2012_Neuropsychologia_50_2093Acetylcholinesterase inhibitors reduce spreading activation in dementia
Fowler_2012_Br.J.Pharmacol_166_1568Monoacylglycerol lipase - a target for drug development?
Fowler_2012_Hum.Genet_131_941Utility of genetically modified mice for understanding the neurobiology of substance use disorders
Fowler_2012_Neuropsychopharmacology_37_306Habenular signaling in nicotine reinforcement
Frakey_2012_J.Clin.Psychiatry_73_796A randomized, double-blind, placebo-controlled trial of modafinil for the treatment of apathy in individuals with mild-to-moderate Alzheimer's disease
Franchi_2012_Eur.Neuropsychopharmacol_22_569Changes in trend of antipsychotics prescription in patients treated with cholinesterase inhibitors after warnings from Italian Medicines Agency. Results from the EPIFARM-Elderly Project
Francis_2012_Expert.Rev.Neurother_12_1351Rationale for combining glutamatergic and cholinergic approaches in the symptomatic treatment of Alzheimer's disease
Francis_2012_Mol.Plant.Microbe.Interact_25_637pFiD188, the linear virulence plasmid of Rhodococcus fascians D188
Francis_2012_Neuropsychopharmacology_37_1934Reduced tissue levels of noradrenaline are associated with behavioral phenotypes of the TgCRND8 mouse model of Alzheimer's disease
Francisco_2012_J.Nat.Prod_75_408Pyridine alkaloids from Senna multijuga as acetylcholinesterase inhibitors
Franke_2012_Fortschr.Neurol.Psychiatr_80_130[Stimulant and non-stimulant medication in current and future therapy for ADHD]
Frasch_2012_Prog.Lipid.Res_51_199Emerging roles for lysophosphatidylserine in resolution of inflammation
Freret_2012_Behav.Brain.Res_230_304Synergistic effect of acetylcholinesterase inhibition (donepezil) and 5-HT(4) receptor activation (RS67333) on object recognition in mice
Frischknecht_2012_Adv.Exp.Med.Biol_970_153The brain's extracellular matrix and its role in synaptic plasticity
Fritschy_2012_Cell.Mol.Life.Sci_69_2485Molecular and functional heterogeneity of GABAergic synapses
Fruchart-Gaillard_2012_PLoS.One_7_e39166Engineering of three-finger fold toxins creates ligands with original pharmacological profiles for muscarinic and adrenergic receptors
Frushicheva_2012_Chembiochem_13_215Towards quantitative computer-aided studies of enzymatic enantioselectivity: the case of Candida antarctica lipase A
Fu_2012_Am.J.Physiol.Lung.Cell.Mol.Physiol_303_L661The ly-6 protein, lynx1, is an endogenous inhibitor of nicotinic signaling in airway epithelium
Fu_2012_J.Biomed.Mater.Res.B.Appl.Biomater_100_314Active screen plasma surface modification of polycaprolactone to improve cell attachment
Fuchs-Buder_2012_Curr.Opin.Anaesthesiol_25_217Is sugammadex economically viable for routine use
Fuchs_2012_Hepatology_56_270Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in mice
Fucinos_2012_Methods.Mol.Biol_861_239Lipases and esterases from extremophiles: overview and case example of the production and purification of an esterase from Thermus thermophilus HB27
Fujii_2012_J.Neuroimmunol_244_16Mediatophore regulates acetylcholine release from T cells
Fujii_2012_Life.Sci_91_981Regulatory mechanisms of acetylcholine synthesis and release by T cells
Fukami_2012_Drug.Metab.Pharmacokinet_27_466The emerging role of human esterases
Furman_2012_Learn.Mem_19_575The episodic engram transformed: Time reduces retrieval-related brain activity but correlates it with memory accuracy
Fusco_2012_Neurobiol.Dis_46_225Changes in the expression of extracellular regulated kinase (ERK 1/2) in the R6/2 mouse model of Huntington's disease after phosphodiesterase IV inhibition
Futahashi_2012_BMC.Biol_10_46Comprehensive microarray-based analysis for stage-specific larval camouflage pattern-associated genes in the swallowtail butterfly, Papilio xuthus
Gabrielsen_2012_J.Bacteriol_194_6976Genome sequence of the bacteriocin-producing strain Lactococcus garvieae DCC43
Gaechter_2012_J.Bacteriol_194_5126Genome sequence of Enterococcus hirae (Streptococcus faecalis) ATCC 9790, a model organism for the study of ion transport, bioenergetics, and copper homeostasis
Gaiji_2012_BMC.Res.Notes_5_307The computational-based structure of Dwarf14 provides evidence for its role as potential strigolactone receptor in plants
Gaikaiwari_2012_Bioresour.Technol_108_224Efficient lipase purification using reverse micellar extraction
Galac_2012_BMC.Genomics_13_612Comparative genomics of bacteria in the genus Providencia isolated from wild Drosophila melanogaster
Galdeano_2012_J.Med.Chem_55_661Huprine-tacrine heterodimers as anti-amyloidogenic compounds of potential interest against Alzheimer's and prion diseases
Galitovskiy_2012_Life.Sci_91_1109Muscle sarcomas and alopecia in A/J mice chronically treated with nicotine
Galland_2012_J.Comput.Aided.Mol.Des_26_1111Mapping of the interaction sites of galanthamine: a quantitative analysis through pairwise potentials and quantum chemistry
Gallay_2012_Cereb.Cortex_22_175The insula of Reil revisited: multiarchitectonic organization in macaque monkeys
Gamliel-Lazarovich_2012_Atherosclerosis_222_92Paraoxonase1 deficiency in mice is associated with hypotension and increased levels of 5,6-epoxyeicosatrienoic acid
Gan_2012_J.Bacteriol_194_4759Genome sequence of Hydrogenophaga sp. strain PBC, a 4-aminobenzenesulfonate-degrading bacterium
Gan_2012_J.Bacteriol_194_5137Genome sequence of Novosphingobium sp. strain Rr 2-17, a nopaline crown gall-associated bacterium isolated from Vitis vinifera L. grapevine
Gan_2012_J.Bacteriol_194_5157Genome sequence of Methylobacterium sp. strain GXF4, a xylem-associated bacterium isolated from Vitis vinifera L. grapevine
Gan_2012_J.Bacteriol_194_5979Genome sequence of Acinetobacter baumannii AC12, a polymyxin-resistant strain isolated from Terengganu, Malaysia
Gan_2012_J.Bacteriol_194_5981Whole-genome sequence of Enterobacter sp. strain SST3, an endophyte isolated from Jamaican sugarcane (Saccharum sp.) stalk tissue
Gangoiti_2012_Appl.Environ.Microbiol_78_7229Characterization of a novel subgroup of extracellular medium-chain-length polyhydroxyalkanoate depolymerases from actinobacteria
Ganjalikhany_2012_PLoS.One_7_e40327Functional motions of Candida antarctica lipase B: a survey through open-close conformations
Garbeva_2012_J.Bacteriol_194_4119Draft genome sequence of the antagonistic rhizosphere bacterium Serratia plymuthica strain PRI-2C
Garcia-Ayllon_2012_PLoS.One_7_e44598Readthrough acetylcholinesterase is increased in human liver cirrhosis
Garcia-Hidalgo_2012_Appl.Microbiol.Biotechnol_93_1975Extracellular production of Streptomyces exfoliatus poly(3-hydroxybutyrate) depolymerase in Rhodococcus sp. T104: determination of optimal biocatalyst conditions
Garcia-Mas_2012_Proc.Natl.Acad.Sci.U.S.A_109_11872The genome of melon (Cucumis melo L.)
Garcia-Montes_2012_CNS.Neurol.Disord.Drug.Targets_11_897Is nicotine protective against Parkinson's disease? An experimental analysis
Garcia_2012_Am.J.Physiol.Endocrinol.Metab_303_E551Acetylcholinesterase deficiency contributes to neuromuscular junction dysfunction in type 1 diabetic neuropathy
Garcia_2012_Environ.Microbiol_14_177Complete genome of Candidatus Chloracidobacterium thermophilum, a chlorophyll-based photoheterotroph belonging to the phylum Acidobacteria
Gardebrecht_2012_ISME.J_6_766Physiological homogeneity among the endosymbionts of Riftia pachyptila and Tevnia jerichonana revealed by proteogenomics
Gardiner_2012_PLoS.Pathog_8_E1002952Comparative pathogenomics reveals horizontally acquired novel virulence genes in fungi infecting cereal hosts
Garrido_2012_J.Biosci.Bioeng_113_549Functional analysis of FarA transcription factor in the regulation of the genes encoding lipolytic enzymes and hydrophobic surface binding protein for the degradation of biodegradable plastics in Aspergillus oryzae
Garza_2012_PLoS.ONE_7_E37283Genome-wide study of the defective sucrose fermenter strain of Vibrio cholerae from the Latin American cholera epidemic
Garzetti_2012_BMC.Genomics_13_467Tracing genomic variations in two highly virulent Yersinia enterocolitica strains with unequal ability to compete for host colonization
Gattrell_2012_Bioorg.Med.Chem.Lett_22_2464An example of designed multiple ligands spanning protein classes: dual MCH-1R antagonists/DPPIV inhibitors
Gaur_2012_Drug.Chem.Toxicol_35_218Effect of nonselective and selective COX-2 inhibitors on memory dysfunction, glutathione system, and tumor necrosis factor alpha level against cerebral ischemia reperfusion injury
Gehret_2012_Protein.Sci_21_239Structure and activity of DmmA, a marine haloalkane dehalogenase
Gelinas_2012_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_161_261Early biochemical effects of Microcystis aeruginosa extracts on juvenile rainbow trout (Oncorhynchus mykiss)
Geng_2012_PLoS.One_7_e34769Complete genome and transcriptomes of Streptococcus parasanguinis FW213: phylogenic relations and potential virulence mechanisms
George_2012_J.Biol.Chem_287_25151Function of human alpha3beta4alpha5 nicotinic acetylcholine receptors is reduced by the alpha5(D398N) variant
Georgiev_2012_Phytother.Res_26_313Cholinesterases inhibitory and antioxidant activities of Harpagophytum procumbens from in vitro systems
Gerke_2012_Appl.Environ.Microbiol_78_8234Breaking the silence: protein stabilization uncovers silenced biosynthetic gene clusters in the fungus Aspergillus nidulans
Geromichalos_2012_J.Agric.Food.Chem_60_6131Saffron as a source of novel acetylcholinesterase inhibitors: molecular docking and in vitro enzymatic studies
Geyer_2012_Biochim.Biophys.Acta_1823_368Nicotinic stimulation induces Tristetraprolin over-production and attenuates inflammation in muscle
Ghatreh_2012_Iran.J.Public.Health_41_59The -514C/T Polymorphism of Hepatic Lipase Gene among Iranian Patients with Coronary Heart Disease
Ghedini_2012_Brain.Res_1483_96Quantitative changes of nicotinic receptors in the hippocampus of dystrophin-deficient mice
Ghosh_2012_Curr.Opin.Endocrinol.Diabetes.Obes_19_136Early steps in reverse cholesterol transport: cholesteryl ester hydrolase and other hydrolases
Gibbons_2012_Methods.Mol.Biol_864_117An introduction to planar chromatography and its application to natural products isolation
Giessing_2012_Front.Behav.Neurosci_6_53Pro-cognitive drug effects modulate functional brain network organization
Giessing_2012_Neuroimage_59_831Genetic variation in nicotinic receptors affects brain networks involved in reorienting attention
Gil_2012_Hum.Exp.Toxicol_31_1299A case of methanol intoxication caused by methomyl pesticide ingestion
Gilboa-Geffen_2012_Front.Mol.Neurosci_5_30Stressing hematopoiesis and immunity: an acetylcholinesterase window into nervous and immune system interactions
Gill_2012_Mol.Pharmacol_81_710A series of alpha7 nicotinic acetylcholine receptor allosteric modulators with close chemical similarity but diverse pharmacological properties
Gillespie_2012_BJU.Int_110_E132Modulation of non-voiding activity by the muscarinergic antagonist tolterodine and the beta(3)-adrenoceptor agonist mirabegron in conscious rats with partial outflow obstruction
Gilligan_2012_Am.J.Geriatr.Pharmacother_10_303Racial and ethnic disparities in Alzheimer's disease pharmacotherapy exposure: an analysis across four state medicaid populations
Gin_2012_Hum.Mol.Genet_21_2961Chylomicronemia mutations yield new insights into interactions between lipoprotein lipase and GPIHBP1
Girgenti_2012_PLoS.One_7_e32404ZNF804a regulates expression of the schizophrenia-associated genes PRSS16, COMT, PDE4B, and DRD2
Giridharan_2012_Free.Radic.Res_46_50Schisandrin B, attenuates cisplatin-induced oxidative stress, genotoxicity and neurotoxicity through modulating NF-kappaB pathway in mice
Girish_2012_Neurotoxicol_33_444Propensity of Selaginella delicatula aqueous extract to offset rotenone-induced oxidative dysfunctions and neurotoxicity in Drosophila melanogaster: Implications for Parkinson's disease
Girones-Vilaplana_2012_Food.Chem_134_2090Phytochemical profile of a blend of black chokeberry and lemon juice with cholinesterase inhibitory effect and antioxidant potential
Girones-Vilaplana_2012_J.Agric.Food.Chem_60_6571New beverages of lemon juice enriched with the exotic berries maqui, acai, and blackthorn: bioactive components and in vitro biological properties
Girousse_2012_Int.J.Obes.(Lond)_36_581Adipocyte lipases and lipid droplet-associated proteins: insight from transgenic mouse models
Gjorlund_2012_Faseb.J_26_4174Neuroligin-1 induces neurite outgrowth through interaction with neurexin-1beta and activation of fibroblast growth factor receptor-1
Glavan_2012_PLoS.One_7_e36114Differential patterns of synaptotagmin7 mRNA expression in rats with kainate- and pilocarpine-induced seizures
Gnamm_2012_Bioorg.Med.Chem.Lett_22_3800Novel diamide insecticides: sulfoximines, sulfonimidamides and other new sulfonimidoyl derivatives
Gnatek_2012_Front.Mol.Neurosci_5_66Acetylcholinesterase loosens the brain's cholinergic anti-inflammatory response and promotes epileptogenesis
Godinho_2012_Adv.Synth.Catal_354_3009An esterase with superior activity and enantioselectivity towards 1,2-O-isopropylideneglycerol esters obtained by protein design
Godinho_2012_J.Biotechnol_158_36Enhancement of the enantioselectivity of carboxylesterase A by structure-based mutagenesis
Goel_2012_Indian.J.Clin.Biochem_27_34Regeneration of Red Cell Cholinesterase Activity Following Pralidoxime (2-PAM) Infusion in First 24 h in Organophosphate Poisoned Patients
Gogliettino_2012_PLoS.One_7_e37921Identification and characterisation of a novel acylpeptide hydrolase from Sulfolobus solfataricus: structural and functional insights
Goh_2012_Appl.Environ.Microbiol_78_70Engineering of bacterial methyl ketone synthesis for biofuels
Goldberg_2012_Handb.Exp.Pharmacol_208_223Muscarinic modulation of striatal function and circuitry
Goldberg_2012_J.Med.Chem_55_10652Free-Wilson and structural approaches to co-optimizing human and rodent isoform potency for 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitors
Golding_2012_J.Bacteriol_194_6627whole-genome sequence of livestock-associated st398 methicillin-resistant staphylococcus aureus Isolated from Humans in Canada
Goldsmith_2012_Chem.Biol_19_456Evolved stereoselective hydrolases for broad-spectrum G-type nerve agent detoxification
Goldsmith_2012_Curr.Opin.Struct.Biol_22_406Directed enzyme evolution: beyond the low-hanging fruit
Goldwirt_2012_J.Pharm.Biomed.Anal_66_325A new UPLC-MS/MS method for the determination of irinotecan and 7-ethyl-10-hydroxycamptothecin (SN-38) in mice: application to plasma and brain pharmacokinetics
Golechha_2012_J.Environ.Biol_33_95Studies on effects of Emblica officinalis (Amla) on oxidative stress and cholinergic function in scopolamine induced amnesia in mice
Goliasch_2012_Clin.Chem_58_1055Butyrylcholinesterase activity predicts long-term survival in patients with coronary artery disease
Goliasch_2012_Eur.Heart.J_33_2282Routinely available biomarkers improve prediction of long-term mortality in stable coronary artery disease: the Vienna and Ludwigshafen Coronary Artery Disease (VILCAD) risk score
Golicnik_2012_Acta.Chim.Slov_59_207Estimation of kinetic parameters for enzyme-inhibition reaction models using direct time-dependent equations for reactant concentrations
Gomes_2012_J.Trop.Med_2012_184819Investigation of Association between Susceptibility to Leprosy and SNPs inside and near the BCHE Gene of Butyrylcholinesterase
Gomes_2012_Nanotoxicology_6_134Effect of Cu-nanoparticles versus one Cu-salt: analysis of stress biomarkers response in Enchytraeus albidus (Oligochaeta)
Gomez-Cambronero_2012_Methods.Mol.Biol_861_201Cloning of PLD2 from baculovirus for studies in inflammatory responses
Gomez-Varela_2012_J.Neurosci_32_6894PMCA2 via PSD-95 controls calcium signaling by alpha7-containing nicotinic acetylcholine receptors on aspiny interneurons
Goncalves_2012_Biometals_25_1195Hematological indices and activity of NTPDase and cholinesterase enzymes in rats exposed to cadmium and treated with N-acetylcysteine
Goncalves_2012_Ultrason.Sonochem_19_232Palm oil hydrolysis catalyzed by lipases under ultrasound irradiation--the use of experimental design as a tool for variables evaluation
Gondret_2012_J.Proteomics_75_949A comparison of subcutaneous adipose tissue proteomes in juvenile piglets with a contrasted adiposity underscored similarities with human obesity
Gong_2012_Biosens.Bioelectron_38_43Highly sensitive visible light activated photoelectrochemical biosensing of organophosphate pesticide using biofunctional crossed bismuth oxyiodide flake arrays
Gong_2012_Drug.Metab.Dispos_40_219Identification of the oxidative and conjugative enzymes involved in the biotransformation of brivanib
Gong_2012_J.Bacteriol_194_1633Genome sequence of Comamonas testosteroni ATCC 11996, a representative strain involved in steroid degradation
Gonzalez-Gutierrez_2012_Proc.Natl.Acad.Sci.U.S.A_109_6331Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals
Gonzalez-Rey_2012_Environ.Pollut_173C_200Does selective serotonin reuptake inhibitor (SSRI) fluoxetine affects mussel Mytilus galloprovincialis?
Gonzalez_2012_J.Expo.Sci.Environ.Epidemiol_22_641Cholinesterase and paraoxonase (PON1) enzyme activities in Mexican-American mothers and children from an agricultural community
Gorbi_2012_Chemosphere_89_623Biological effects of palytoxin-like compounds from Ostreopsis cf. ovata: a multibiomarkers approach with mussels Mytilus galloprovincialis
Gordon_2012_Dement.Geriatr.Cogn.Dis.Extra_2_312An Open-Label Exploratory Study with Memantine: Correlation between Proton Magnetic Resonance Spectroscopy and Cognition in Patients with Mild to Moderate Alzheimer's Disease
Gordon_2012_J.Econ.Entomol_105_971Association of esterases with insecticide resistance in Culex quinquefasciatus (Diptera: Culicidae)
Gore_2012_Toxicol.Sci_126_515Efficacy assessment of various anticholinergic agents against topical sarin-induced miosis and visual impairment in rats
Gorecki_2012_Ann.Bot_109_1369Parental environment changes the dormancy state and karrikinolide response of Brassica tournefortii seeds
Gorelick_2012_Future.Med.Chem_4_227Pharmacokinetic strategies for treatment of drug overdose and addiction
Goriounova_2012_Cold.Spring.Harb.Perspect.Med_2_a012120Short- and long-term consequences of nicotine exposure during adolescence for prefrontal cortex neuronal network function
Goriounova_2012_Front.Synaptic.Neurosci_4_3Nicotine exposure during adolescence alters the rules for prefrontal cortical synaptic plasticity during adulthood
Goriounova_2012_J.Neurosci_32_10484Nicotine exposure during adolescence leads to short- and long-term changes in spike timing-dependent plasticity in rat prefrontal cortex
Gotoda_2012_J.Atheroscler.Thromb_19_1Diagnosis and management of type I and type V hyperlipoproteinemia
Gotz_2012_Br.J.Pharmacol_165_1246Tau-targeted treatment strategies in Alzheimer's disease
Gou_2012_Plant.Cell_24_50Acetylesterase-mediated deacetylation of pectin impairs cell elongation, pollen germination, and plant reproduction
Goudet_2012_FASEB.J_26_1682A novel selective metabotropic glutamate receptor 4 agonist reveals new possibilities for developing subtype selective ligands with therapeutic potential
Goulet_2012_Proc.Natl.Acad.Sci.U.S.A_109_19009Role of an esterase in flavor volatile variation within the tomato clade
Govil_2012_Biol.Trace.Elem.Res_146_402Postnuclear supernatant: an in vitro model for assessing cadmium-induced neurotoxicity
Govind_2012_J.Neurosci_32_2227Nicotine-induced upregulation of native neuronal nicotinic receptors is caused by multiple mechanisms
Grabus_2012_Nicotine.Tob.Res_14_1356Bupropion and its main metabolite reverse nicotine chronic tolerance in the mouse
Grad_2012_Proc.Natl.Acad.Sci.U.S.A_109_3065Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011
Graebin_2012_Biotechnol.Prog_28_406Immobilization of lipase B from Candida antarctica on porous styrene-divinylbenzene beads improves butyl acetate synthesis
Graff-Radford_2012_Brain_135_2470Imaging and acetylcholinesterase inhibitor response in dementia with Lewy bodies
Grallert_2012_Eur.Heart.J_33_238Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies
Grandic_2012_Bioorg.Med.Chem_20_1659Binding and permeabilization of lipid bilayers by natural and synthetic 3-alkylpyridinium polymers
Grandic_2012_Toxicol.Appl.Pharmacol_265_221The non-competitive acetylcholinesterase inhibitor APS12-2 is a potent antagonist of skeletal muscle nicotinic acetylcholine receptors
Grando_2012_Autoimmunity_45_7Pemphigus autoimmunity: hypotheses and realities
Grando_2012_Handb.Exp.Pharmacol_208_429Muscarinic receptor agonists and antagonists: effects on keratinocyte functions
Grando_2012_Life.Sci_91_969The non-neuronal cholinergic system: basic science, therapeutic implications and new perspectives
Grasemann_2012_PLoS.One_7_e46618L-ornithine derived polyamines in cystic fibrosis airways
Green_2012_Postgrad.Med_124_54The dipeptidyl peptidase-4 inhibitors in type 2 diabetes mellitus: cardiovascular safety
Greenblatt_2012_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_F68_269Structure of Recombinant Human Carboxylesterase 1 Isolated from Whole Cabbage Looper Larvae
Gregg_2012_J.Neurosci_32_9457Activation of type 5 metabotropic glutamate receptors and diacylglycerol lipase-alpha initiates 2-arachidonoylglycerol formation and endocannabinoid-mediated analgesia
Gregory_2012_J.Biol.Chem_287_37066Stimulus bias provides evidence for conformational constraints in the structure of a G protein-coupled receptor
Gremos_2012_Bioresour.Technol_115_96Supercritical carbon dioxide biocatalysis as a novel and green methodology for the enzymatic acylation of fibrous cellulose in one step
Grenier_2012_Biochem.Pharmacol_83_1465The low intestinal and hepatic toxicity of hydrolyzed fumonisin B(1) correlates with its inability to alter the metabolism of sphingolipids
Griebling_2012_J.Urol_188_891Re: Concomitant use of cholinesterase inhibitors and anticholinergics: prevalence and outcomes
Grimaud_2012_J.Bacteriol_194_3539Genome sequence of the marine bacterium Marinobacter hydrocarbonoclasticus SP17, which forms biofilms on hydrophobic organic compounds
Grimster_2012_J.Am.Chem.Soc_134_6732Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template
Grisouard_2012_Innate.Immun_18_25Both inflammatory and classical lipolytic pathways are involved in lipopolysaccharide-induced lipolysis in human adipocytes
Grote_2012_Proc.Natl.Acad.Sci.U.S.A_109_506Genome and physiology of a model Epsilonproteobacterium responsible for sulfide detoxification in marine oxygen depletion zones
Grove_2012_Obesity.(Silver.Spring)_20_2311(-)-Epigallocatechin-3-gallate inhibits pancreatic lipase and reduces body weight gain in high fat-fed obese mice
Grover_2012_J.Biomol.Struct.Dyn_29_651Computational evidence to inhibition of human acetyl cholinesterase by withanolide a for Alzheimer treatment
Gruber_2012_Methods.Mol.Biol_861_313Molecular modeling of lipase binding to a substrate-water interface
Grundman_2012_J.Nutr.Health.Aging_16_336Is there a rationale for including only patients already being treated with acetylcholinesterase inhibitors in a prodromal AD trial?
Grzegorzewicz_2012_Nat.Chem.Biol_8_334Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane
Gu_2012_J.Neurosci_32_12337Cholinergic coordination of presynaptic and postsynaptic activity induces timing-dependent hippocampal synaptic plasticity
Guan_2012_J.Bacteriol_194_6975Complete genome sequence of Bacillus thuringiensis serovar Sichuansis strain MC28
Guan_2012_J.Pharmacol.Exp.Ther_341_33GABAergic actions mediate opposite ethanol effects on dopaminergic neurons in the anterior and posterior ventral tegmental area
Guan_2012_Plant.Physiol_160_1303Diverse roles of strigolactone signaling in maize architecture and the uncoupling of a branching-specific subnetwork
Guasch_2012_PLoS.One_7_e44971Identification of novel human dipeptidyl peptidase-IV inhibitors of natural origin (part I): virtual screening and activity assays
Gueimonde_2012_J.Bacteriol_194_4776Genome sequence of Parascardovia denticolens IPLA 20019, isolated from human breast milk
Gueimonde_2012_J.Bacteriol_194_6997Genome sequence of the immunomodulatory strain Bifidobacterium bifidum LMG 13195
Guenard_2012_Obesity.(Silver.Spring)_20_2075Association of LIPA gene polymorphisms with obesity-related metabolic complications among severely obese patients
Guergueltcheva_2012_J.Neurol_259_838Congenital myasthenic syndrome with tubular aggregates caused by GFPT1 mutations
Guglielmino_2012_Am.J.Physiol.Heart.Circ.Physiol_303_H853Pharmacological inhibition of soluble epoxide hydrolase provides cardioprotection in hyperglycemic rats
Gumel_2012_Ultrason.Sonochem_19_659Ultrasound assisted lipase catalyzed synthesis of poly-6-hydroxyhexanoate
Gunaletchumy_2012_J.Bacteriol_194_5695Draft genome sequences of Helicobacter pylori isolates from Malaysia, cultured from patients with functional dyspepsia and gastric cancer
Gundelfinger_2012_Curr.Opin.Neurobiol_22_423Molecular organization and plasticity of the cytomatrix at the active zone
Gunduz_2012_J.Emerg.Med_43_1008Pseudocholinesterase levels are not decreased in grayanotoxin (mad honey) poisoning in most patients
Gungordu_2012_Environ.Monit.Assess_184_763Water quality evaluation of two interconnected dam lakes with field-captured and laboratory-acclimated fish, Cyprinus carpio
Gungordu_2012_Environ.Toxicol.Pharmacol_33_431Evaluation of spatial and temporal changes in biomarker responses in the common carp (Cyprinus carpio L.) for biomonitoring the Meric Delta, Turkey
Guo_2012_J.Am.Chem.Soc_134_10244Cholinesterase-responsive supramolecular vesicle
Guo_2012_J.Bacteriol_194_4146Genome of Helicobacter pylori strain XZ274, an isolate from a tibetan patient with gastric cancer in China
Guo_2012_J.Bacteriol_194_6646Draft genome sequence of Rahnella aquatilis strain HX2, a plant growth-promoting rhizobacterium isolated from vineyard soil in Beijing, China
Guo_2012_Lett.Appl.Microbiol_55_162Draft genome sequence of Streptomyces coelicoflavus ZG0656 reveals the putative biosynthetic gene cluster of acarviostatin family alpha-amylase inhibitors
Guo_2012_Neuropharmacol_62_1671Presynaptic muscarinic M(2) receptors modulate glutamatergic transmission in the bed nucleus of the stria terminalis
Guo_2012_Org.Lett_14_5684Molecular genetic characterization of a cluster in A. terreus for biosynthesis of the meroterpenoid terretonin
Guo_2012_PLoS.One_7_e37098Examining the interactome of huperzine A by magnetic biopanning
Gupta_2012_Arterioscler.Thromb.Vasc.Biol_32_1936Soluble epoxide hydrolase: sex differences and role in endothelial cell survival
Gupta_2012_Gene_498_13Low serum PON1 activity: an independent risk factor for coronary artery disease in North-West Indian type 2 diabetics
Gutierrez_2012_J.Bacteriol_194_6967Draft genome sequence of Methanobacterium formicicum DSM 3637, an Archaebacterium isolated from the methane producer amoeba Pelomyxa palustris
Guttery_2012_PLoS.Pathog_8_e1002554A putative homologue of CDC20/CDH1 in the malaria parasite is essential for male gamete development
Guttery_2012_PLoS.Pathog_8_e1002948A unique protein phosphatase with kelch-like domains (PPKL) in Plasmodium modulates ookinete differentiation, motility and invasion
Guven_2012_Pediatr.Neurol_46_253Recurrent COLQ mutation in congenital myasthenic syndrome
Gwaram_2012_Molecules_17_2408Synthesis, characterization, X-ray crystallography, acetyl cholinesterase inhibition and antioxidant activities of some novel ketone derivatives of gallic hydrazide-derived Schiff bases
Gyllborg_2012_J.Bacteriol_194_1639Draft genome sequence of Vibrio fischeri SR5, a strain isolated from the light organ of the Mediterranean squid Sepiola robusta
H-Kittikun_2012_Appl.Biochem.Biotechnol_166_1969Sugar ester synthesis by thermostable lipase from Streptomyces thermocarboxydus ME168
Habraken_2012_Macromol.Rapid.Commun_33_272Block copolypeptides prepared by N-carboxyanhydride ring-opening polymerization
Haddad_2012_Angew.Chem.Int.Ed.Engl_51_11126Back-scattering interferometry: an ultrasensitive method for the unperturbed detection of acetylcholinesterase-inhibitor interactions
Haddi_2012_Insect.Biochem.Mol.Biol_42_506Identification of mutations associated with pyrethroid resistance in the voltage-gated sodium channel of the tomato leaf miner (Tuta absoluta)
Hadj-Said_2012_Muscle.Nerve_45_567Effect of locomotor training on muscle performance in the context of nerve-muscle communication dysfunction
Haense_2012_Neurobiol.Aging_33_867Cholinergic system function and cognition in mild cognitive impairment
Haga_2012_Nature_482_547Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
Hager_2012_J.Biol.Chem_287_20755Lecithin:cholesterol acyltransferase deficiency protects against cholesterol-induced hepatic endoplasmic reticulum stress in mice
Hain_2012_BMC.Genomics_13_144Comparative genomics and transcriptomics of lineages I, II, and III strains of Listeria monocytogenes
Haines_2012_Curr.Treat.Options.Neurol_14_103Treatment of ocular myasthenia gravis
Hakkinen_2012_Microb.Cell.Fact_11_134Re-annotation of the CAZy genes of Trichoderma reesei and transcription in the presence of lignocellulosic substrates
Halliday_2012_Protein.Pept.Lett_19_165From protein to peptides: a spectrum of non-hydrolytic functions of acetylcholinesterase
Hamiaux_2012_Curr.Biol_22_2032DAD2 Is an alpha/beta Hydrolase Likely to Be Involved in the Perception of the Plant Branching Hormone, Strigolactone
Hamilton_2012_Clin.Chim.Acta_413_1207A new method for the measurement of lysosomal acid lipase in dried blood spots using the inhibitor Lalistat 2
Hamulakova_2012_Eur.J.Med.Chem_55_23Synthesis, design and biological evaluation of novel highly potent tacrine congeners for the treatment of Alzheimer's disease
Han_2012_Anal.Chim.Acta_720_126Chromogenic platform based on recombinant Drosophila melanogaster acetylcholinesterase for visible unidirectional assay of organophosphate and carbamate insecticide residues
Han_2012_Asian.Pac.J.Trop.Med_5_966Effects of AIBL on Oncomelania hupensis, the intermediate snail host of Schistosoma japonicum: An enzyme histochemical study
Han_2012_Biochem.J_446_253Biochemical identification and crystal structure of kynurenine formamidase from Drosophila melanogaster.
Han_2012_Brain.Res_1470_59Reversal of scopolamine-induced spatial and recognition memory deficits in mice by novel multifunctional dimers bis-cognitins
Han_2012_Eur.J.Clin.Pharmacol_68_599Mixed-effect circadian rhythm model for human erythrocyte acetylcholinesterase activity--application to the proof of concept of cholinesterase inhibition by acorn extract in healthy subjects with galantamine as positive control
Han_2012_J.Bacteriol_194_4463Complete genome sequence of the metabolically versatile halophilic archaeon Haloferax mediterranei, a poly(3-hydroxybutyrate-co-3-hydroxyvalerate) producer
Han_2012_J.Bacteriol_194_5472Genome sequence of Streptomyces auratus strain AGR0001, a phoslactomycin-producing actinomycete
Han_2012_Stand.Genomic.Sci_6_94Complete genome sequence of the sulfur compounds oxidizing chemolithoautotroph Sulfuricurvum kujiense type strain (YK-1(T))
Hang_2012_Appl.Environ.Microbiol_78_1962SulE, a sulfonylurea herbicide de-esterification esterase from Hansschlegelia zhihuaiae S113
Haninec_2012_BMC.Neurosci_13_57Enhancement of musculocutaneous nerve reinnervation after vascular endothelial growth factor (VEGF) gene therapy
Haninec_2012_Plast.Reconstr.Surg_130_609A Comparison of collateral sprouting of sensory and motor axons after end-to-side neurorrhaphy with and without the perineurial window
Hansen_2012_Appl.Environ.Microbiol_78_4908Involvement of a natural fusion of a cytochrome P450 and a hydrolase in mycophenolic acid biosynthesis
Hao_2012_Appl.Environ.Microbiol_78_5384Genome sequence and mutational analysis of plant-growth-promoting bacterium Agrobacterium tumefaciens CCNWGS0286 Isolated from a zinc-lead mine tailing
Hao_2012_J.Bacteriol_194_3264The genome of plant growth-promoting Bacillus amyloliquefaciens subsp. plantarum strain YAU B9601-Y2 contains a gene cluster for mersacidin synthesis
Hao_2012_J.Bacteriol_194_736Draft genome sequence of plant growth-promoting rhizobium Mesorhizobium amorphae, isolated from zinc-lead mine tailings
Hao_2012_J.Bacteriol_194_903Genome sequence of the arsenite-oxidizing strain Agrobacterium tumefaciens 5A
Hargreaves_2012_Adv.Exp.Med.Biol_724_189Neurodegenerations induced by organophosphorous compounds
Harmey_2012_Nicotine.Tob.Res_14_1300Development of novel pharmacotherapeutics for tobacco dependence: progress and future directions
Hartsel_2012_Bioorg.Med.Chem.Lett_22_4593Re-engineering aryl methylcarbamates to confer high selectivity for inhibition of Anopheles gambiae versus human acetylcholinesterase
Hartz_2012_Arch.Gen.Psychiatry_69_854Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers
Hartz_2012_BMC.Neurol_12_2Evaluating the cost effectiveness of donepezil in the treatment of Alzheimer's disease in Germany using discrete event simulation
Harvey_2012_Handb.Exp.Pharmacol_208_299Muscarinic receptor agonists and antagonists: effects on cardiovascular function
Hassan_2012_J.Bacteriol_194_5718Whole-genome sequence of Corynebacterium pseudotuberculosis strain Cp162, isolated from camel
Hassan_2012_Parasit.Vectors_5_46Insecticide resistance in the sand fly, Phlebotomus papatasi from Khartoum State, Sudan
Hassan_2012_Phytochem.Anal_23_405TLC bioautographic method for detecting lipase inhibitors
Hatfull_2012_J.Virol_86_2382Complete genome sequences of 138 mycobacteriophages
Hattori_2012_Structure_20_1293A fluorescence-detection size-exclusion chromatography-based thermostability assay for membrane protein precrystallization screening
Hauser_2012_Neuropharmacol_62_2239Comparison of acetylcholine receptor interactions of the marine toxins, 13-desmethylspirolide C and gymnodimine
Hayden_2012_PLoS.ONE_7_E36507Evolution of Burkholderia pseudomallei in recurrent melioidosis
Hazen_2012_J.Bacteriol_194_3026Draft genome sequences of the diarrheagenic Escherichia coli collection
He_2012_Aquat.Toxicol_124-125_28Pyrene exposure influences the thyroid development of Sebastiscus marmoratus embryos
He_2012_Arch.Insect.Biochem.Physiol_79_75RNA interference of two acetylcholinesterase genes in Plutella xylostella reveals their different functions
He_2012_Bioresour.Technol_114_1Lipase-mediated synthesis of water-soluble plant stanol derivatives in tert-butanol
He_2012_Chem.Biol_19_1313Quartromicin biosynthesis: two alternative polyketide chains produced by one polyketide synthase assembly line
He_2012_Chin.Med.J.(Engl)_125_2272Comparison of four prognostic models and a new Logistic regression model to predict short-term prognosis of acute-on-chronic hepatitis B liver failure
He_2012_J.Biotechnol_164_281Genome sequence of the plant growth promoting strain Bacillus amyloliquefaciens subsp. plantarum B9601-Y2 and expression of mersacidin and other secondary metabolites
He_2012_Zhonghua.Lao.Dong.Wei.Sheng.Zhi.Ye.Bing.Za.Zhi_30_863[To evaluate the therapeutic efficacy of hemoperfusion in treating intermediate symdrome following acute organophosphate poisoning]
Hebert_2012_J.Bacteriol_194_538Genome sequence of the bacteriocin-producing Lactobacillus curvatus strain CRL705
Hedge_2012_Biochim.Biophys.Acta_1824_1024The structural basis for the narrow substrate specificity of an acetyl esterase from Thermotoga maritima
Heeb_2012_Environ.Sci.Technol_46_6566Biotransformation of Hexabromocyclododecanes (HBCDs) with LinB--an HCH-converting bacterial enzyme
Heffernan_2012_J.Wildl.Dis_48_695Combined effect of short-term dehydration and sublethal acute oral dicrotophos exposure confounds the diagnosis of anticholinesterase exposure in common quail (Coturnix coturnix) using plasma cholinesterase activity
Heggeset_2012_Appl.Environ.Microbiol_78_5170Genome sequence of thermotolerant Bacillus methanolicus: features and regulation related to methylotrophy and production of L-lysine and L-glutamate from methanol
Hein_2012_Vet.Rec_171_218Reference ranges for laboratory parameters in ferrets
Heinl_2012_J.Biotechnol_161_153Insights into the completely annotated genome of Lactobacillus buchneri CD034, a strain isolated from stable grass silage
Heller_2012_PLoS.One_7_e39572The biochemical anatomy of cortical inhibitory synapses
Hemshekhar_2012_Basic.Clin.Pharmacol.Toxicol_110_122Emerging roles of anacardic acid and its derivatives: a pharmacological overview
Henderson_2012_ACS.Chem.Neurosci_3_682Defining the putative inhibitory site for a selective negative allosteric modulator of human alpha4beta2 neuronal nicotinic receptors
Henderson_2012_Bioorg.Med.Chem.Lett_22_17973D-QSAR and 3D-QSSR models of negative allosteric modulators facilitate the design of a novel selective antagonist of human alpha4beta2 neuronal nicotinic acetylcholine receptors
Henderson_2012_J.Biochem.Mol.Toxicol_26_31Pyridostigmine bromide protection against acetylcholinesterase inhibition by pesticides
Herkert_2012_Toxicol.Lett_209_173Comparative kinetics of organophosphates and oximes with erythrocyte, muscle and brain acetylcholinesterase
Hernandez_2012_Curr.Drug.Targets_13_613alpha7 nicotinic acetylcholine receptors in Alzheimer's disease: neuroprotective, neurotrophic or both?
Hernando_2012_Mol.Pharmacol_82_550Contribution of subunits to Caenorhabditis elegans levamisole-sensitive nicotinic receptor function
Herrera-Lopez_2012_Methods.Mol.Biol_861_525Lipase and phospholipase biosensors: a review
Heselich_2012_Photochem.Photobiol_88_135Near-infrared exposure changes cellular responses to ionizing radiation
Hesse_2012_Mol.Biol.Rep_39_761Sequence and expression of the chicken membrane-associated phospholipases A1 alpha (LIPH) and beta (LIPI)
Heylen_2012_Front.Microbiol_3_371Redundancy and modularity in membrane-associated dissimilatory nitrate reduction in Bacillus
Hicks_2012_Front.Physiol_3_189Lipid rafts and Alzheimer's disease: protein-lipid interactions and perturbation of signaling
Hiessl_2012_Appl.Environ.Microbiol_78_2874Involvement of two latex-clearing proteins during rubber degradation and insights into the subsequent degradation pathway revealed by the genome sequence of Gordonia polyisoprenivorans strain VH2
Hieu_2012_J.Med.Entomol_49_1084Toxicity of Zanthoxylum piperitum and Zanthoxylum armatum oil constituents and related compounds to Stomoxys calcitrans (Diptera: Muscidae)
Higaki_2012_Magn.Reson.Imaging_30_689Potential clinical factors affecting hepatobiliary enhancement at Gd-EOB-DTPA-enhanced MR imaging
Hilario_2012_Neuropsychopharmacology_37_2661Reward sensitization: effects of repeated nicotine exposure and withdrawal in mice
Hira_2012_FEBS.Lett_586_1658Anammox organism KSU-1 expresses a NirK-type copper-containing nitrite reductase instead of a NirS-type with cytochrome cd1
Hiraishi_2012_Macromol.Biosci_12_218Display of functionally active PHB depolymerase on Escherichia coli cell surface
Hirano_2012_J.Neurol.Neurosurg.Psychiatry_83_963Functional brain imaging of cognitive dysfunction in Parkinson's disease
Hirano_2012_Protein.Pept.Lett_19_180Molecular determinants that convert hormone sensitive lipase into gibberellin receptor
Hiraoka_2012_Eur.Neurol_68_137Cholinergic deficit and response to donepezil therapy in Parkinson's disease with dementia
Hlady_2012_J.Clin.Invest_122_163Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesis
Ho_2012_J.Bacteriol_194_6337Complete genome sequence of Mycobacterium fortuitum subsp. fortuitum type strain DSM46621
Ho_2012_J.Bacteriol_194_6339Complete genome sequence of Mycobacterium vaccae type strain ATCC 25954
Hobley_2012_BMC.Genomics_13_670Genome analysis of a simultaneously predatory and prey-independent, novel Bdellovibrio bacteriovorus from the River Tiber, supports in silico predictions of both ancient and recent lateral gene transfer from diverse bacteria
Hochwind_2012_J.Bacteriol_194_6638Draft genome sequence of Lactobacillus casei W56
Hoepfner_2012_Cell.Host.Microbe_11_654Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin
Hoffman_2012_Int.J.Obstet.Anesth_21_281Urgent cesarean delivery and prolonged ventilatory support in a parturient with Fontan circulation and undiagnosed pseudocholinesterase deficiency
Hoffmann_2012_Int.J.Syst.Evol.Microbiol_62_1736Vibrio caribbeanicus sp. nov., isolated from the marine sponge Scleritoderma cyanea
Hoffmann_2012_J.Bacteriol_194_3274Genome sequences of five Salmonella enterica serovar Heidelberg isolates associated with a 2011 multistate outbreak in the United States
Hoglund_2012_J.Alzheimers.Dis_32_939Longitudinal stability evaluation of biomarkers and their correlation in cerebrospinal fluid and plasma from patients with Alzheimer's disease
Holas_2012_Expert.Opin.Drug.Discov_7_1207The progress in the cholinesterase quantification methods
Holden-Dye_2012_Invert.Neurosci_12_29Worms take to the slo lane: a perspective on the mode of action of emodepside
Hollenhorst_2012_Life.Sci_91_1009Nicotine-induced activation of soluble adenylyl cyclase participates in ion transport regulation in mouse tracheal epithelium
Hone_2012_FASEB.J_26_917Nicotinic acetylcholine receptors in dorsal root ganglion neurons include the alpha6beta4* subtype
Hone_2012_Mol.Pharmacol_82_972alpha-Conotoxin PeIA[S9H,V10A,E14N] potently and selectively blocks alpha6beta2beta3 versus alpha6beta4 nicotinic acetylcholine receptors
Hong_2012_Biomacromolecules_13_3686Synthesis, characterization, and paclitaxel release from a biodegradable, elastomeric, poly(ester urethane)urea bearing phosphorylcholine groups for reduced thrombogenicity
Hong_2012_J.Bacteriol_194_6317Complete genome sequence of Burkholderia sp. Strain GG4, a betaproteobacterium that reduces 3-oxo-N-acylhomoserine lactones and produces different N-acylhomoserine lactones
Hong_2012_Mol.Med.Rep_5_142Computational pharmaceutical analysis of anti-Alzheimer's Chinese medicine Coptidis Rhizoma alkaloids
Hong_2012_Sensors.(Basel)_12_4661Quorum quenching revisited--from signal decays to signalling confusion
Hopkins_2012_Neuropsychopharmacology_37_2310Galantamine, an acetylcholinesterase inhibitor and positive allosteric modulator of nicotinic acetylcholine receptors, attenuates nicotine taking and seeking in rats
Hopp_2012_PLoS.One_7_e48206Spatiotemporal and functional characterisation of the Plasmodium falciparum cGMP-dependent protein kinase
Horchani_2012_Methods.Mol.Biol_861_267Purification, biochemical and kinetic properties of recombinant Staphylococcus aureus lipase
Hori_2012_Xenobiotica_42_614Dexamethasone-mediated transcriptional regulation of rat carboxylesterase 2 gene
Hormigo_2012_Bioresour.Technol_115_177Preparation and characterization of cross-linked enzyme aggregates (CLEAs) of recombinant poly-3-hydroxybutyrate depolymerase from Streptomyces exfoliatus
Horst_2012_Behav.Brain.Res_231_170Impaired auditory discrimination learning following perinatal nicotine exposure or beta2 nicotinic acetylcholine receptor subunit deletion
Horvath_2012_J.Bacteriol_194_202Genome sequence of Propionibacterium acnes type II strain ATCC 11828
Hosseini_2012_Arterioscler.Thromb.Vasc.Biol_32_1204Transgenic expression and genetic variation of Lmf1 affect LPL activity in mice and humans
Hou_2012_Biosens.Bioelectron_33_44Amperometric acetylcholine biosensor based on self-assembly of gold nanoparticles and acetylcholinesterase on the sol-gel/multi-walled carbon nanotubes/choline oxidase composite-modified platinum electrode
Hou_2012_Org.Lett_14_5050Structure and biosynthesis of the antibiotic bottromycin D
Hou_2012_World.J.Microbiol.Biotechnol_28_541Catalytic characteristics of plant-esterase from wheat flour
Howard_2012_Biodegradation_23_561Growth of Acinetobacter gerneri P7 on polyurethane and the purification and characterization of a polyurethanase enzyme
Howard_2012_Langmuir_28_12030Carboxylesterase-Triggered Hydrolysis of Nanoparticle PEGylating Agents
Howard_2012_N.Engl.J.Med_366_893Donepezil and memantine for moderate-to-severe Alzheimer's disease
Hoyle_2012_Neurogastroenterol.Motil_24_586Effects of aging on cholinergic neuromuscular transmission in isolated small intestine of ad libitum fed and calorically-restricted rats
Hsu_2012_Anal.Biochem_427_1A chip-based method for studying the effects of exogenous proteins on neuronal axons
Hsu_2012_Nat.Chem.Biol_8_999DAGLbeta inhibition perturbs a lipid network involved in macrophage inflammatory responses
Hsu_2012_Probe.Report__Optimization and characterization of a triazole urea inhibitor for diacylglycerol lipase beta (DAGL-beta)
Hu_2012_Biochem.Biophys.Res.Commun_419_617Functional characterization of lipase in the pathogenesis of Staphylococcus aureus
Hu_2012_Extremophiles_16_79A novel, extremely alkaliphilic and cold-active esterase from Antarctic desert soil
Hu_2012_Mol.Genet.Metab_107_213Intravenous high-dose enzyme replacement therapy with recombinant palmitoyl-protein thioesterase reduces visceral lysosomal storage and modestly prolongs survival in a preclinical mouse model of infantile neuronal ceroid lipofuscinosis
Hu_2012_Science_337_980Neurexin and neuroligin mediate retrograde synaptic inhibition in C. elegans
Hua_2012_J.Bacteriol_194_6979Genome sequences of two multidrug-resistant Acinetobacter baumannii strains isolated from a patient before and after treatment with tigecycline
Huang_2012_Bioorg.Med.Chem_20_3038Inhibition of cholinesterase activity and amyloid aggregation by berberine-phenyl-benzoheterocyclic and tacrine-phenyl-benzoheterocyclic hybrids
Huang_2012_J.Bacteriol_194_1256Complete genome sequence of Staphylococcus aureus M013, a pvl-positive, ST59-SCCmec type V strain isolated in Taiwan
Huang_2012_J.Bacteriol_194_1635Genome sequence of the facultative anaerobic arsenite-oxidizing and nitrate-reducing bacterium Acidovorax sp. strain NO1
Huang_2012_J.Phys.Chem.B_116_3361Cocaine esterase-cocaine binding process and the free energy profiles by molecular dynamics and potential of mean force simulations
Huang_2012_J.Phys.Chem.B_116_532Microscopic binding of M5 muscarinic acetylcholine receptor with antagonists by homology modeling, molecular docking, and molecular dynamics simulation
Huang_2012_J.Virol_86_12467Genomic sequence of Heliothis virescens ascovirus 3g isolated from Spodoptera exigua
Huang_2012_Neuron_74_801Estradiol acutely suppresses inhibition in the hippocampus through a sex-specific endocannabinoid and mGluR-dependent mechanism
Huang_2012_Planta.Med_78_65Bioactive isoquinoline alkaloids from Corydalis saxicola
Huang_2012_Zhonghua.Er.Ke.Za.Zhi_50_601[Wolman disease with novel mutation of LIPA gene in a Chinese infant]
Huen_2012_Environ.Res_117_8Organophosphate pesticide levels in blood and urine of women and newborns living in an agricultural community
Huggett_2012_J.Bacteriol_194_2393Genome sequence of strain HIMB55, a novel marine gammaproteobacterium of the OM60/NOR5 clade
Huh_2012_Muscle.Nerve_46_600Limb-girdle myasthenia with tubular aggregates associated with novel GFPT1 mutations
Huntley_2012_J.Bacteriol_194_3012Complete genome sequence of the fruiting myxobacterium Corallococcus coralloides DSM 2259
Huo_2012_J.Bacteriol_194_197Complete genome sequence of Pelagibacterium halotolerans B2(T)
Hussein_2012_Int.J.Hepatol_2012_265305Paraoxonase activity and expression is modulated by therapeutics in experimental rat nonalcoholic Fatty liver disease
Hussmann_2012_J.Pharmacol.Exp.Ther_343_441Chronic sazetidine-A at behaviorally active doses does not increase nicotinic cholinergic receptors in rodent brain
Husson_2012_Curr.Biol_22_743Optogenetic analysis of a nociceptor neuron and network reveals ion channels acting downstream of primary sensors
Hutter_2012_J.Colloid.Interface.Sci_365_53Interfacial and self-assembly properties of bolaamphiphilic compounds derived from a multifunctional oil
Huynh_2012_Bull.Environ.Contam.Toxicol_88_25Effects of chlorpyrifos exposure on growth and food utilization in Australian catfish, Tandanus tandanus
Hwang_2012_J.Microbiol.Biotechnol_22_239Changes in the activities of enzymes involved in the degradation of butylbenzyl phthalate by Pleurotus ostreatus
Ibanez-Tallon_2012_Curr.Opin.Neurobiol_22_72Tethering toxins and peptide ligands for modulation of neuronal function
Ibrahim_2012_Bioconjug.Chem_23_2403Design, synthesis, and X-ray analysis of a glycoconjugate bound to Mycobacterium tuberculosis antigen 85C
Igarashi_2012_J.Toxicol.Sci_37_373Development of humanized steroid and xenobiotic receptor mouse by homologous knock-in of the human steroid and xenobiotic receptor ligand binding domain sequence
Ignasik_2012_Arch.Pharm.(Weinheim)_345_509Design, synthesis and evaluation of novel 2-(aminoalkyl)-isoindoline-1,3-dione derivatives as dual-binding site acetylcholinesterase inhibitors
Imanishi_2012_Adv.Pharmacol.Sci_2012_708178Effect of a CNS-Sensitive Anticholinesterase Methane Sulfonyl Fluoride on Hippocampal Acetylcholine Release in Freely Moving Rats
Imramovsky_2012_Molecules_17_10142Acetylcholinesterase-inhibiting activity of salicylanilide N-alkylcarbamates and their molecular docking
Insenser_2012_Mol.Cell.Endocrinol_363_10A nontargeted proteomic approach to the study of visceral and subcutaneous adipose tissue in human obesity
Inui_2012_J.Cosmet.Sci_63_259Inhibition of sebum production and Propionibacterium acnes lipase activity by fullerenol, a novel polyhydroxylated fullerene: potential as a therapeutic reagent for acne
Ireland_2012_J.Appl.Physiol.(1985)_113_1024Muscarinic acetylcholine receptors enhance neonatal mouse hypoglossal motoneuron excitability in vitro
Irlinger_2012_J.Bacteriol_194_5141Genome sequence of Staphylococcus equorum subsp. equorum Mu2, isolated from a French smear-ripened cheese
Isanapong_2012_J.Bacteriol_194_2744High-quality draft genome sequence of the Opitutaceae bacterium strain TAV1, a symbiont of the wood-feeding termite Reticulitermes flavipes
Isaza_2012_FEMS.Microbiol.Lett_330_113Whole genome shotgun sequencing of one Colombian clinical isolate of Mycobacterium tuberculosis reveals DosR regulon gene deletions
Ishikawa_2012_Int.J.Hypertens_2012_948203Vasculitis, Atherosclerosis, and Altered HDL Composition in Heme-Oxygenase-1-Knockout Mice
Isik_2012_Intern.Med_51_575Cardiac safety of donepezil in elderly patients with Alzheimer disease
Isik_2012_J.Nutr.Health.Aging_16_139aChE and BuChE inhibition by rivastigmin have no effect on peripheral insulin resistance in elderly patients with Alzheimer disease
Islam_2012_BMC.Genomics_13_493Tools to kill: genome of one of the most destructive plant pathogenic fungi Macrophomina phaseolina
Ismail_2012_Molecules_17_7217Synthesis and biological evaluation of thiophene derivatives as acetylcholinesterase inhibitors
Israeli_2012_Clin.Exp.Dermatol_37_31Beneficial effect of acitretin in Chanarin-Dorfman syndrome
Itagaki_2012_Drug.Metab.Dispos_40_1138Electrophysiological characterization of the polyspecific organic cation transporter plasma membrane monoamine transporter
Ito_2012_Appl.Microbiol.Biotechnol_96_1059A novel actinomycete derived from wheat heads degrades deoxynivalenol in the grain of wheat and barley affected by Fusarium head blight
Ito_2012_Mol.Ther_20_1384Protein-anchoring strategy for delivering acetylcholinesterase to the neuromuscular junction
Itoh_2012_ChemBioChem_13_1132Identification of a key prenyltransferase involved in biosynthesis of the most abundant fungal meroterpenoids derived from 3,5-dimethylorsellinic acid
Itoh_2012_J.Biol.Chem_287_13859Methyl CpG-binding protein isoform MeCP2_e2 is dispensable for Rett syndrome phenotypes but essential for embryo viability and placenta development
Itziou_2012_Ecotoxicol.Environ.Saf_86_13Multiple pollution biomarker application on tissues of Eobania vermiculata during two periods characterized by augmented and reduced snail activity
Iwakura_2012_J.Neurosci_32_9438Lack of molecular-anatomical evidence for GABAergic influence on axon initial segment of cerebellar Purkinje cells by the pinceau formation
Iwamura_2012_J.Biol.Chem_287_9240Human alpha/beta hydrolase domain containing 10 (ABHD10) is responsible enzyme for deglucuronidation of mycophenolic acid acyl-glucuronide in liver
Iyer_2012_Exp.Diabetes.Res_2012_758614Pharmacological inhibition of soluble epoxide hydrolase ameliorates diet-induced metabolic syndrome in rats
Jackson_2012_Genes.Brain.Behav_11_993Acute behavioral effects of nicotine in male and female HINT1 knockout mice
Jackson_2012_J.Org.Chem_77_10435Stability of cyclic imine toxins: interconversion of pinnatoxin amino ketone and pinnatoxin A in aqueous media
Jackson_2012_PLoS.One_7_e51154Nicotine reward and affective nicotine withdrawal signs are attenuated in calcium/calmodulin-dependent protein kinase IV knockout mice
Jacobsen_2012_Neurosci.Lett_515_7The alpha4beta2 nicotine acetylcholine receptor agonist ispronicline induces c-Fos expression in selective regions of the rat forebrain
Jafari_2012_Toxicol.Mech.Methods_22_638The role of oxidative stress in diazinon-induced tissues toxicity in Wistar and Norway rats
Jahanshahi-Anbuhi_2012_Lab.Chip_12_5079Creating fast flow channels in paper fluidic devices to control timing of sequential reactions
Jala_2012_Methods.Mol.Biol_861_403Lipases as biocatalysts for the synthesis of structured lipids
Jalkanen_2012_Neurochem.Int_60_301The effect of prolyl oligopeptidase inhibition on extracellular acetylcholine and dopamine levels in the rat striatum
Jang_2012_J.Bacteriol_194_3263Genome sequence of cold-adapted Pseudomonas mandelii strain JR-1
Jankowitsch_2012_J.Bacteriol_194_6818Genome sequence of the bacterium Streptomyces davawensis JCM 4913 and heterologous production of the unique antibiotic roseoflavin
Janssen_2012_Front.Plant.Sci_3_296Strigolactone and karrikin signal perception: receptors, enzymes, or both?
Jaromin_2012_Biol.Pharm.Bull_35_1432Membrane perturbations induced by new analogs of neocryptolepine
Jellinger_2012_Expert.Rev.Neurother_12_1451Neurobiology of cognitive impairment in Parkinson's disease
Jemec_2012_Arch.Environ.Contam.Toxicol_62_210Assessment of landfill leachate toxicity reduction after biological treatment
Jensen_2012_Aging.Cell_11_82A new role for laminins as modulators of protein toxicity in Caenorhabditis elegans
Jensen_2012_Am.J.Physiol.Gastrointest.Liver.Physiol_302_G473Autocrine regulation of biliary pathology by activated cholangiocytes
Jeon_2012_Appl.Microbiol.Biotechnol_93_623Identification of a new subfamily of salt-tolerant esterases from a metagenomic library of tidal flat sediment
Jerng_2012_PLoS.One_7_e38205Incorporation of DPP6a and DPP6K variants in ternary Kv4 channel complex reconstitutes properties of A-type K current in rat cerebellar granule cells
Jett_2012_Neurotoxicol_33_1473Chemical toxins that cause seizures
Ji_2012_ScientificWorldJournal_2012_823201Molecular basis of inhibitory activities of berberine against pathogenic enzymes in Alzheimer's disease
Jiang_2012_Arch.Microbiol_194_207Identification and characterization of novel esterases from a deep-sea sediment metagenome
Jiang_2012_Bioorg.Med.Chem.Lett_22_3632A specific molecular beacon probe for the detection of human prostate cancer cells
Jiang_2012_Extremophiles_16_427Cloning, expression and characterization of a halotolerant esterase from a marine bacterium Pelagibacterium halotolerans B2T
Jiang_2012_J.Anim.Physiol.Anim.Nutr.(Berl)_96_1147Effect on hepatonephric organs, serum metabolites and oxidative stress in post-weaning piglets fed purified zearalenone-contaminated diets with or without Calibrin-Z
Jiang_2012_J.Bacteriol_194_5481Draft genome sequences of Enterobacter sp. isolate Ag1 from the midgut of the malaria mosquito Anopheles gambiae
Jiang_2012_Toxicology_295_15Mice treated with a nontoxic dose of chlorpyrifos oxon have diethoxyphosphotyrosine labeled proteins in blood up to 4 days post exposure, detected by mass spectrometry
Jimenez_2012_World.J.Microbiol.Biotechnol_28_361A novel cold active esterase derived from Colombian high Andean forest soil metagenome
Jin_2012_Bioresour.Technol_116_234Overexpression and characterization of a new organic solvent-tolerant esterase derived from soil metagenomic DNA
Jin_2012_Proc.Natl.Acad.Sci.U.S.A_109_9131Spontaneous transmitter release is critical for the induction of long-term and intermediate-term facilitation in Aplysia
Jin_2012_Proc.Natl.Acad.Sci.U.S.A_109_9137Spontaneous transmitter release recruits postsynaptic mechanisms of long-term and intermediate-term facilitation in Aplysia
Jindrichova_2012_PLoS.One_7_e32073Changes in temperature have opposing effects on current amplitude in alpha7 and alpha4beta2 nicotinic acetylcholine receptors
Jirimutu_2012_Nat.Commun_3_1202Genome sequences of wild and domestic bactrian camels
Joh_2012_Phytother.Res_26_546Kalopanaxsaponins A and B isolated from Kalopanax pictus ameliorate memory deficits in mice
John_2012_Drug.Test.Anal_4_169Quantification of pralidoxime (2-PAM) in urine by ion pair chromatography-diode array detection: application to in vivo samples from minipig
John_2012_Drug.Test.Anal_4_179Review of UV spectroscopic, chromatographic, and electrophoretic methods for the cholinesterase reactivating antidote pralidoxime (2-PAM)
John_2012_J.Biomol.Struct.Dyn_29_921Potential human cholesterol esterase inhibitor design: benefits from the molecular dynamics simulations and pharmacophore modeling studies
Johnson_2012_Biochemistry_51_6238Solvent-Dependent Gating Motions of an Extremophilic Lipase from Pseudomonas aeruginosa
Johnson_2012_Comp.Biochem.Physiol.Part.D.Genomics.Proteomics_7_83The carboxylesterase/cholinesterase gene family in invertebrate deuterostomes
Johnson_2012_Neurochem.Int_61_783Why has butyrylcholinesterase been retained? Structural and functional diversification in a duplicated gene
Johnson_2012_Psychopharmacology.(Berl)_222_269Assessing the effects of chronic sazetidine-A delivery on nicotine self-administration in both male and female rats
Johnston_2012_Bioorg.Med.Chem.Lett_22_4585Assay and inhibition of diacylglycerol lipase activity
Johri_2012_World.J.Microbiol.Biotechnol_28_193Novel thermostable lipase from Bacillus circulans IIIB153: comparison with the mesostable homologue at sequence and structure level
Jokanovic_2012_Curr.Top.Med.Chem_12_1775Structure-activity relationship and efficacy of pyridinium oximes in the treatment of poisoning with organophosphorus compounds: a review of recent data
Jones_2012_Front.Physiol_3_239Role of Cholinergic Innervation and RGS2 in Atrial Arrhythmia
Jones_2012_J.Pharmacol.Exp.Ther_340_404The metabotropic glutamate receptor 4-positive allosteric modulator VU0364770 produces efficacy alone and in combination with L-DOPA or an adenosine 2A antagonist in preclinical rodent models of Parkinson's disease
Jones_2012_Neuropsychopharmacology_37_16Muscarinic and nicotinic acetylcholine receptor agonists and allosteric modulators for the treatment of schizophrenia
Jordaan_2012_Ecotoxicology_21_649Acute and sublethal effects of sequential exposure to the pesticide azinphos-methyl on juvenile earthworms (Eisenia andrei)
Jose_2012_Diab.Vasc.Dis.Res_9_109Cardiovascular effects of the DPP-4 inhibitors
Joseph_2012_PLoS.ONE_7_e49455Comparative analysis of genome sequences covering the seven cronobacter species
Joshi_2012_Exp.Toxicol.Pathol_64_103Therapeutic potential of N-acetyl cysteine with antioxidants (Zn and Se) supplementation against dimethylmercury toxicity in male albino rats
Joshi_2012_Exp.Toxicol.Pathol_64_115Hyperglycemic and stressogenic effects of monocrotophos in rats: evidence for the involvement of acetylcholinesterase inhibition
Joshi_2012_J.Bacteriol_194_6329Draft genome sequence of Pontibacter sp. nov. BAB1700, a halotolerant, industrially important bacterium
Joussen_2012_Proc.Natl.Acad.Sci.U.S.A_109_15206Resistance of Australian Helicoverpa armigera to fenvalerate is due to the chimeric P450 enzyme CYP337B3
Ju_2012_J.Clin.Microbiol_50_4123Phylogenetic analysis of non-O157 Shiga toxin-producing Escherichia coli strains by whole-genome sequencing
Jukic_2012_Nat.Prod.Res_26_1703Screening for acetylcholinesterase inhibition and antioxidant activity of selected plants from Croatia
Jung_2012_Arterioscler.Thromb.Vasc.Biol_32_2929Fatty Acids Regulate Endothelial Lipase and Inflammatory Markers in Macrophages and in Mouse Aorta: A Role for PPARgamma
Jung_2012_J.Bacteriol_194_2097Genome sequence of extracellular-protease-producing Alishewanella jeotgali isolated from traditional Korean fermented seafood
Jung_2012_J.Bacteriol_194_5476Genome sequence of pectin-degrading Alishewanella aestuarii strain B11(T), isolated from tidal flat sediment
Jung_2012_J.Bacteriol_194_6665Complete genome sequence of Leuconostoc gelidum strain JB7, isolated from kimchi
Jung_2012_J.Bacteriol_194_6672Complete genome sequence of Leuconostoc carnosum strain JB16, isolated from kimchi
Jung_2012_J.Bacteriol_194_730Complete genome sequence of Leuconostoc mesenteroides subsp. mesenteroides strain J18, isolated from kimchi
Jung_2012_Korean.J.Physiol.Pharmacol_16_231Effects of single treatment of anti-dementia drugs on sleep-wake patterns in rats
Jung_2012_Nat.Commun_3_1080Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome
Jung_2012_Phytomedicine_20_84Lancemaside A isolated from Codonopsis lanceolata and its metabolite echinocystic acid ameliorate scopolamine-induced memory and learning deficits in mice
Kaas_2012_Nucleic.Acids.Res_40_D325ConoServer: updated content, knowledge, and discovery tools in the conopeptide database
Kabbani_2012_Curr.Drug.Targets_13_72Dopamine receptor interacting proteins: targeting neuronal calcium sensor-1/D2 dopamine receptor interaction for antipsychotic drug development
Kaboudin_2012_Bioorg.Chem_41-42_22Synthesis and inhibitory activity of ureidophosphonates, against acetylcholinesterase: pharmacological assay and molecular modeling
Kahne_2012_Proteomics_12_2433Synaptic proteome changes in mouse brain regions upon auditory discrimination learning
Kalantari-Dehaghi_2012_Life.Sci_91_1122Reciprocal effects of NNK and SLURP-1 on oncogene expression in target epithelial cells
Kalashnyk_2012_Life.Sci_91_1033Intracellular localization of nicotinic acetylcholine receptors in human cell lines
Kalemenev_2012_Dokl.Biol.Sci_443_78Neuroprotective effect of noncompetitive NMDA receptor antagonists IEM-1957 and memantine in experimental focal cerebral ischemia
Kalisiak_2012_J.Med.Chem_55_465Nonquaternary reactivators for organophosphate-inhibited cholinesterases
Kallendrusch_2012_PLoS.One_7_e51208Intrinsic up-regulation of 2-AG favors an area specific neuronal survival in different in vitro models of neuronal damage
Kalmar_2012_Amyotroph.Lateral.Scler_13_378Treatment with a coinducer of the heat shock response delays muscle denervation in the SOD1-G93A mouse model of amyotrophic lateral sclerosis
Kalousova_2012_Tumour.Biol_33_1695Ferritin as an independent mortality predictor in patients with pancreas cancer. Results of a pilot study
Kamal_2012_PLoS.One_7_e35188Role of active site rigidity in activity: MD simulation and fluorescence study on a lipase mutant
Kamate_2012_Pediatr.Neurol_46_325Novel neuroimaging finding in palmitoyl protein thioesterase-1-related neuronal ceroid lipofuscinosis
Kamel_2012_Arch.Environ.Contam.Toxicol_63_534Increased temperatures affect oxidative stress markers and detoxification response to benzo[a]pyrene exposure in mussel Mytilus galloprovincialis
Kamel_2012_Ecotoxicol.Environ.Saf_82_40Biochemical responses and metals levels in Ruditapes decussatus after exposure to treated municipal effluents
Kan_2012_Int.J.Food.Sci.Nutr_63_1In-vitro neuroprotective properties of the Maydis stigma extracts from four corn varieties
Kanesaki_2012_DNA.Res_19_67Identification of substrain-specific mutations by massively parallel whole-genome resequencing of Synechocystis sp. PCC 6803
Kang_2012_J.Asia.Pac.Entomol_15_383One-step identification of B and Q biotypes of Bemisia tabaci based on intron variation of carboxylesterase 2
Kang_2012_J.Asia.Pac.Entomol_15_389Proteomics-based identification and characterization of biotype-specific carboxylesterase 2 putatively associated with insecticide resistance in Bemisia tabaci
Kang_2012_Molecules_18_140Inhibitory evaluation of sulfonamide chalcones on beta-secretase and acylcholinesterase
Kang_2012_Pestic.Biochem.Physiol_104_157Inhibition properties of three acetylcholinesterases of the pinewood nematode Bursaphelenchus xylophilus by organophosphates and carbamates
Kanno_2012_J.Toxicol.Sci_37_389Enhancement of anti-cholinesterase activity of aqueous samples by hypochlorite oxidation for monitoring traces of organophosphorus pesticides in water
Kantak_2012_Appl.Biochem.Biotechnol_166_1769Characterization of smallest active monomeric lipase from novel rhizopus strain: application in transesterification
Kapai_2012_Cell.Mol.Neurobiol_32_219Donepezil in a narrow concentration range augments control and impaired by beta-amyloid peptide hippocampal LTP in NMDAR-independent manner
Kapanda_2012_J.Med.Chem_55_5774Synthesis and pharmacological evaluation of 2,4-dinitroaryldithiocarbamate derivatives as novel monoacylglycerol lipase inhibitors
Kar_2012_Bioprocess.Biosyst.Eng_35_483Physical and physiological impacts of different foam control strategies during a process involving hydrophobic substrate for the lipase production by Yarrowia lipolytica
Karageorgos_2012_ACS.Chem.Neurosci_3_393Endocannabinoid enzyme engineering: soluble human thio-monoacylglycerol lipase (sol-S-hMGL)
Karakaya_2012_Curr.Treat.Options.Neurol_14_126Treatment options for tauopathies
Karakus_2012_Toxicol.Ind.Health_30_421Cases of organophosphate poisoning treated with high-dose of atropine in an intensive care unit and the novel treatment approaches
Karched_2012_J.Bacteriol_194_1275Genome sequence of Aggregatibacter actinomycetemcomitans RHAA1, isolated from a rhesus macaque, an Old World primate
Karlsson_2012_Eur.J.Pharm.Sci_45_169Identification and characterization of diarylimidazoles as hybrid inhibitors of butyrylcholinesterase and amyloid beta fibril formation
Karlsson_2012_Eur.J.Pharm.Sci_47_190The exploration of thienothiazines as selective butyrylcholinesterase inhibitors
Karon_2012_Blood.Transfus_10_453Temporal sequence of major biochemical events during blood bank storage of packed red blood cells
Karray_2012_Methods.Mol.Biol_861_283Phospholipase A2 purification and characterization: a case study
Kaschani_2012_Bioorg.Med.Chem_20_597Selective inhibition of plant serine hydrolases by agrochemicals revealed by competitive ABPP
Kassa_2012_Acta.Medica.(Hradec.Kralove)_55_27The ability of oxime mixtures to increase the reactivating and therapeutic efficacy of antidotal treatment of cyclosarin poisoning in rats and mice
Kassa_2012_Basic.Clin.Pharmacol.Toxicol_110_322A comparison of the efficacy of newly developed reversible inhibitors of acetylcholinesterase with commonly used pyridostigmine as pharmacological pre-treatment of soman-poisoned mice
Kassa_2012_Mini.Rev.Med.Chem_12_24Two possibilities how to increase the efficacy of antidotal treatment of nerve agent poisonings
Kasuya_2012_Alzheimer.Dis.Assoc.Disord_26_113Greater responsiveness to donepezil in Alzheimer patients with higher levels of acetylcholinesterase based on attention task scores and a donepezil PET study
Kaszuba_2012_Biochimie_94_1398Molecular dynamics, crystallography and mutagenesis studies on the substrate gating mechanism of prolyl oligopeptidase.
Katalinic_2012_Croatica.Chem.Acta_85_209Reactivation of Tabun-inhibited Acetylcholinesterase Investigated by Two Oximes and Mutagenesis
Kato_2012_Bioorg.Med.Chem.Lett_22_6410Substrate-like water soluble lipase inhibitors from Filipendula kamtschatica
Kato_2012_J.Bacteriol_194_2102Complete genome sequence of Lactococcus lactis IO-1, a lactic acid bacterium that utilizes xylose and produces high levels of L-lactic acid
Kaur_2012_J.Biochem.Mol.Toxicol_26_393Attenuation of cellular antioxidant defense mechanisms in kidney of rats intoxicated with carbofuran
Kavlock_2012_Chem.Res.Toxicol_25_1287Update on EPA's ToxCast program: providing high throughput decision support tools for chemical risk management
Kawashima_2012_Ann.N.Y.Acad.Sci_1261_7Reconciling neuronally and nonneuronally derived acetylcholine in the regulation of immune function
Kawashima_2012_Life.Sci_91_1027Critical roles of acetylcholine and the muscarinic and nicotinic acetylcholine receptors in the regulation of immune function
Kazenwadel_2012_Enzyme.Microb.Technol_51_9Thiol-functionalization of acrylic ester monomers catalyzed by immobilized Humicola insolens cutinase
Kazi_2012_Neurotoxicol_33_1284The effect of acute severe monocrotophos poisoning on inhibition, expression and activity of acetylcholinesterase in different rat brain regions
Kazi_2012_Neurotoxicol_33_156Monocrotophos induced oxidative damage associates with severe acetylcholinesterase inhibition in rat brain
Keeling_2012_Insect.Biochem.Mol.Biol_42_525Transcriptome and full-length cDNA resources for the mountain pine beetle, Dendroctonus ponderosae Hopkins, a major insect pest of pine forests
Kempster_2012_Am.J.Physiol.Endocrinol.Metab_302_E103Disruption of paraoxonase 3 impairs proliferation and antioxidant defenses in human A549 cells and causes embryonic lethality in mice
Kenakin_2012_ACS.Chem.Neurosci_3_193A simple method for quantifying functional selectivity and agonist bias
Kennett_2012_Nicotine.Tob.Res_14_1339Pharmacological differences between rat frontal cortex and hippocampus in the nicotinic modulation of noradrenaline release implicate distinct receptor subtypes
Kenri_2012_J.Bacteriol_194_1253Complete genome sequence of Mycoplasma pneumoniae type 2a strain 309, isolated in Japan
Kergourlay_2012_J.Bacteriol_194_3008Genome sequence of Lactobacillus salivarius SMXD51, a potential probiotic strain isolated from chicken cecum, showing anti-campylobacter activity
Khaibullina_2012_PLoS.One_7_e48733In a model of Batten disease, palmitoyl protein thioesterase-1 deficiency is associated with brown adipose tissue and thermoregulation abnormalities
Khalaf_2012_Neurotoxicol_33_280The protective effect of green tea extract on lead induced oxidative and DNA damage on rat brain
Khan_2012_BMC.Complement.Altern.Med_12_219Effects of Launaea procumbens on brain antioxidant enzymes and cognitive performance of rat
Khan_2012_Behav.Brain.Funct_8_21Brain antioxidant markers, cognitive performance and acetylcholinesterase activity of rats: efficiency of Sonchus asper
Khan_2012_Biosens.Bioelectron_31_433Multienzyme microbiosensor based on electropolymerized o-phenylenediamine for simultaneous in vitro determination of acetylcholine and choline
Khare_2012_Nat.Chem.Biol_8_294Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis
Khateeb_2012_Arterioscler.Thromb.Vasc.Biol_32_449Urokinase-type plasminogen activator downregulates paraoxonase 1 expression in hepatocytes by stimulating peroxisome proliferator-activated receptor-gamma nuclear export
Khatri_2012_J.Bacteriol_194_6363Draft genome sequence of Rhodovulum sp. strain PH10, a phototrophic alphaproteobacterium isolated from a soil sample of mangrove of Namkhana, India
Khokhar_2012_Toxicol.Sci_126_325Rat brain CYP2B-enzymatic activation of chlorpyrifos to the oxon mediates cholinergic neurotoxicity
Khoo_2012_Funct.Plant.Biol_39_222Preliminary characterisation of two early meiotic wheat proteins after identification through 2D gel electrophoresis proteomics.
Khorana_2012_Bioorg.Med.Chem.Lett_22_2885Prospective acetylcholinesterase inhibitory activity of indole and its analogs
Khovidhunkit_2012_Am.J.Cardiol_110_62Resequencing CETP, LIPC and LIPG genes in Thai subjects with hyperalphalipoproteinemia
Khurana_2012_Hum.Exp.Toxicol_31_686Protective role of curcumin on colchicine-induced cognitive dysfunction and oxidative stress in rats
Kiage-Mokua_2012_Phytother.Res_26_1878Lapacho Tea (Tabebuia impetiginosa) Extract Inhibits Pancreatic Lipase and Delays Postprandial Triglyceride Increase in Rats
Kim_2012_BMC.Microbiol_12_21Genome sequence of Desulfitobacterium hafniense DCB-2, a Gram-positive anaerobe capable of dehalogenation and metal reduction
Kim_2012_Evid.Based.Complement.Alternat.Med_2012_878365Inhibitory Activities of Cudrania tricuspidata Leaves on Pancreatic Lipase In Vitro and Lipolysis In Vivo
Kim_2012_FEBS.Lett_586_3962NDRG2 and PRA1 interact and synergistically inhibit T-cell factor/beta-catenin signaling.
Kim_2012_J.Asia.Pac.Entomol_15_401Mutation in ace1 associated with an insecticide resistant population of Plutella xylostella
Kim_2012_J.Bacteriol_194_2750Complete genome sequence of Mycobacterium intracellulare strain ATCC 13950(T)
Kim_2012_J.Bacteriol_194_2771Complete genome sequence of Mycobacterium intracellulare clinical strain MOTT-02
Kim_2012_J.Bacteriol_194_3268Complete genome sequence of Mycobacterium intracellulare clinical strain MOTT-64, belonging to the INT1 genotype
Kim_2012_J.Bacteriol_194_3753Genome sequence of the unclassified marine Gammaproteobacterium BDW918
Kim_2012_J.Bacteriol_194_3758Genome sequence of the leaf-colonizing Bacterium Bacillus sp. strain 5B6, isolated from a cherry tree
Kim_2012_J.Bacteriol_194_4141Complete genome sequence of Mycobacterium intracellulare clinical strain MOTT-36Y, belonging to the INT5 genotype
Kim_2012_J.Bacteriol_194_5134Complete genome sequence of Brucella canis strain HSK A52141, isolated from the blood of an infected dog
Kim_2012_J.Bacteriol_194_5135Genome sequence of pectin-degrading Alishewanella agri, isolated from landfill soil
Kim_2012_J.Bacteriol_194_5149Draft genome sequence of Escherichia coli W26, an enteric strain isolated from cow feces
Kim_2012_J.Bacteriol_194_5444Complete genome sequence of Brucella abortus A13334, a new strain isolated from the fetal gastric fluid of dairy cattle
Kim_2012_J.Bacteriol_194_7003Draft genome sequencing of Bacillus sp. strain M2-6, isolated from the roots of Korean ginseng, Panax ginseng C. A. Meyer, after high-hydrostatic-pressure processing
Kim_2012_J.Biosci.Bioeng_114_589Gene cloning and catalytic characterization of cold-adapted lipase of Photobacterium sp. MA1-3 isolated from blood clam
Kim_2012_J.Lipid.Res_53_2450Dietary cholesterol increases paraoxonase 1 enzyme activity
Kim_2012_J.Lipids_2012_476316Additional Common Polymorphisms in the PON Gene Cluster Predict PON1 Activity but Not Vascular Disease
Kim_2012_J.Microbiol.Biotechnol_22_1044Cloning and identification of a new group esterase (Est5S) from noncultured rumen bacterium
Kim_2012_J.Microbiol.Biotechnol_22_1245Gene cloning and characterization of a cold-adapted esterase from Acinetobacter venetianus V28
Kim_2012_Life.Sci_90_21DA-1229, a novel and potent DPP4 inhibitor, improves insulin resistance and delays the onset of diabetes
Kim_2012_PLoS.One_7_e48838Molecular and kinetic properties of two acetylcholinesterases from the western honey bee, Apis mellifera
Kim_2012_Plant.Cell_24_5177Natural variation in small molecule-induced TIR-NB-LRR signaling induces root growth arrest via EDS1- and PAD4-complexed R protein VICTR in Arabidopsis
Kimes_2012_ISME.J_6_835Temperature regulation of virulence factors in the pathogen Vibrio coralliilyticus
Kimura_2012_Neurosci.Lett_529_70Dexmedetomidine decreases hyperalgesia in neuropathic pain by increasing acetylcholine in the spinal cord
Kirshner_2012_J.Mol.Neurosci_46_554Malfunctioning DNA damage response (DDR) leads to the degeneration of nigro-striatal pathway in mouse brain
Kist_2012_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_155_247Microcystin-LR acute exposure increases AChE activity via transcriptional ache activation in zebrafish (Danio rerio) brain
Kistemaker_2012_Life.Sci_91_1126Regulation of airway inflammation and remodeling by muscarinic receptors: perspectives on anticholinergic therapy in asthma and COPD
Kitadokoro_2012_Polym.Degrad.Stab_97_771Crystal structure of cutinase Est119 from Thermobifida alba AHK119 that can degrade modified polyethylene terephthalate at 1.76A resolution
Kitazawa_2012_Am.J.Med.Genet.B.Neuropsychiatr.Genet_159B_456No associations found between the genes situated at 6p22.1, HIST1H2BJ, PRSS16, and PGBD1 in Japanese patients diagnosed with schizophrenia
Klenk_2012_Stand.Genomic.Sci_6_220Genome sequence of the soil bacterium Saccharomonospora azurea type strain (NA-128(T))
Klenk_2012_Stand.Genomic.Sci_6_265Genome sequence of the ocean sediment bacterium Saccharomonospora marina type strain (XMU15(T))
Kliemann_2012_Life.Sci_91_997Quantitative analyses of bone composition in acetylcholine receptor M3R and alpha7 knockout mice
Klimaviciusa_2012_J.Neurosci.Methods_204_104In situ prolyl oligopeptidase activity assay in neural cell cultures
Klinzing_2012_J.Bacteriol_194_542Shotgun genome sequence of a Yersinia enterocolitica isolate from the Philippines
Klooster_2012_Brain_135_1081Muscle-specific kinase myasthenia gravis IgG4 autoantibodies cause severe neuromuscular junction dysfunction in mice
Klugman_2012_J.Alzheimers.Dis_30_467Antioxidant enzymatic activities in Alzheimer's disease: the relationship to acetylcholinesterase inhibitors
Knaack_2012_Anal.Chem_84_10052High-Throughput Immunomagnetic Scavenging Technique for Quantitative Analysis of Live VX Nerve Agent in Water, Hamburger, and Soil Matrixes
Knaack_2012_Anal.Chem_84_9470A high-throughput diagnostic method for measuring human exposure to organophosphorus nerve agents
Knapik_2012_Proteins_80_2359A multi-faceted analysis of RutD reveals a novel family of alpha/beta hydrolases
Ko_2012_J.Ind.Microbiol.Biotechnol_39_681Identification and characterization of a novel cold-adapted esterase from a metagenomic library of mountain soil
Koarai_2012_Eur.Respir.J_39_698Expression of muscarinic receptors by human macrophages
Kobayashi_2012_Biosci.Biotechnol.Biochem_76_2082Enhancement of the Enzymatic Activity of Escherichia coli Acetyl Esterase by a Double Mutation Obtained by Random Mutagenesis
Kobayashi_2012_Drug.Metab.Dispos_40_1080Contributions of arylacetamide deacetylase and carboxylesterase 2 to flutamide hydrolysis in human liver
Kobayashi_2012_Drug.Metab.Dispos_40_671Species differences in tissue distribution and enzyme activities of arylacetamide deacetylase in human, rat, and mouse
Koenig_2012_Mar.Environ.Res_79_122Natural variability of hepatic biomarkers in Mediterranean deep-sea organisms
Kohlhaas_2012_Psychopharmacology.(Berl)_220_823Effects of alpha7 nicotinic acetylcholine receptor agonists on antipsychotic efficacy in a preclinical mouse model of psychosis
Koitabashi_2012_AMB.Express_2_40Degradation of biodegradable plastic mulch films in soil environment by phylloplane fungi isolated from gramineous plants
Koldemir_2012_Diabetes.Metab.Syndr_6_90Relationship of RIC-3 gene rs1528133 polymorphism with varying degrees of body weight and eating behavior
Koliaki_2012_CNS.Neurosci.Ther_18_302Clinical efficacy of aniracetam, either as monotherapy or combined with cholinesterase inhibitors, in patients with cognitive impairment: a comparative open study
Kolton_2012_J.Bacteriol_194_5462Draft genome sequence of Flavobacterium sp. strain F52, isolated from the rhizosphere of bell pepper (Capsicum annuum L. cv. Maccabi)
Konishi_2012_Pharmacology_91_86Donepezil Abolishes Anticholinergic Activity in a Patient with Amnesia
Konrath_2012_J.Ethnopharmacol_139_58Investigation of the in vitro and ex vivo acetylcholinesterase and antioxidant activities of traditionally used Lycopodium species from South America on alkaloid extracts
Konrath_2012_Phytomedicine_19_1321Huperzia quadrifariata and Huperzia reflexa alkaloids inhibit acetylcholinesterase activity in vivo in mice brain
Konukoglu_2012_Acta.Neurol.Belg_112_255Serum brain-derived neurotrophic factor, nerve growth factor and neurotrophin-3 levels in dementia
Koodalingam_2012_Pestic.Biochem.Physiol_104_267Effect of a Bt-based product (Vectobar) on esterases and phosphatases from larvae of the mosquito Aedes aegypti
Koohestani_2012_Int.J.Dev.Neurosci_30_570Differential effects of developmental hypo- and hyperthyroidism on acetylcholinesterase and butyrylcholinesterase activity in the spinal cord of developing postnatal rat pups
Koohestani_2012_Int.J.Dev.Neurosci_30_578Postnatal growth hormone deficiency in growing rats causes marked decline in the activity of spinal cord acetylcholinesterase but not butyrylcholinesterase
Kopkan_2012_Kidney.Blood.Press.Res_35_595Soluble Epoxide Hydrolase Inhibition Exhibits Antihypertensive Actions Independently of Nitric Oxide in Mice with Renovascular Hypertension
Korabecny_2012_Ceska.Slov.Farm_61_210[Tacrine and its derivatives in the therapy of Alzheimers disease]
Korber_2012_Mol.Cell.Neurosci_50_250Effects of distinct collybistin isoforms on the formation of GABAergic synapses in hippocampal neurons
Korman_2012_PLoS.One_7_e52890Crystal Structure of Proteus mirabilis Lipase, a Novel Lipase from the Proteus/Psychrophilic Subfamily of Lipase Family I.1
Kortylewicz_2012_J.Med.Chem_55_2649Radiolabeled cyclosaligenyl monophosphates of 5-iodo-2'-deoxyuridine, 5-iodo-3'-fluoro-2',3'-dideoxyuridine, and 3'-fluorothymidine for molecular radiotherapy of cancer: synthesis and biological evaluation
Kos_2012_MBio_3_e00112Comparative genomics of vancomycin-resistant Staphylococcus aureus strains and their positions within the clade most commonly associated with Methicillin-resistant S. aureus hospital-acquired infection in the United States
Kosari_2012_Behav.Brain.Res_235_98Effect of western and high fat diets on memory and cholinergic measures in the rat
Koskinen_2012_Environ.Toxicol.Pharmacol_34_905Cerebral microvascular effects of nimodipine in combination with soman
Kosovicheva_2012_Front.Behav.Neurosci_6_61Cholinergic enhancement reduces orientation-specific surround suppression but not visual crowding
Kostka_2012_J.Bacteriol_194_4461Genome sequences for six Rhodanobacter strains, isolated from soils and the terrestrial subsurface, with variable denitrification capabilities
Kotagal_2012_Ann.Neurol_71_560Symptoms of rapid eye movement sleep behavior disorder are associated with cholinergic denervation in Parkinson disease
Kotagal_2012_Neurosci.Lett_514_169Thalamic cholinergic innervation is spared in Alzheimer disease compared to parkinsonian disorders
Kotik_2012_J.Microbiol.Methods_88_212Sequence diversity in haloalkane dehalogenases, as revealed by PCR using family-specific primers
Kotoh_2012_Exp.Ther.Med_3_72Serum albumin is present at higher levels in alcoholic liver cirrhosis as compared to HCV-related cirrhosis
Kotur-Stevuljevic_2012_Clin.Biochem_45_1202A hazardous link between malnutrition, inflammation and oxidative stress in renal patients
Koul_2012_Pediatr.Neurol_47_209Rituximab in severe seronegative juvenile myasthenia gravis: review of the literature
Kousi_2012_Hum.Mutat_33_42Update of the mutation spectrum and clinical correlations of over 360 mutations in eight genes that underlie the neuronal ceroid lipofuscinoses
Kovacs_2012_Neuropsychopharmacol.Hung_14_19[Achetylcholinesterase (AChE) inhibition and serum lipokines in Alzheimer's disease: friend or foe?]
Kow_2012_Nature_482_480Structural biology: Muscarinic receptors become crystal clear
Kozak_2012_PLoS.One_7_e30392Inherent plasticity of brown adipogenesis in white fat of mice allows for recovery from effects of post-natal malnutrition
Kracmarova_2012_Neuro.Endocrinol.Lett_33_136Tacrine is implicated in oxidative stress in the laboratory guinea pig model
Krasteva_2012_Histochem.Cell.Biol_137_483Cholinergic chemosensory cells in the auditory tube
Krasteva_2012_Life.Sci_91_992Cholinergic brush cells in the trachea mediate respiratory responses to quorum sensing molecules
Krauland_2012_PLoS.One_7_e35699Whole genome sequencing to investigate the emergence of clonal complex 23 Neisseria meningitidis serogroup Y disease in the United States
Kraus_2012_ChemMedChem_7_357Why as a medicinal chemist I am not optimistic about the possibility of finding, in a reasonable timeframe, small-molecule drugs capable of curing the evolution of Alzheimer's disease
Kretschmann_2012_Environ.Toxicol.Chem_31_2014Toxicokinetic and toxicodynamic model for diazinon toxicity-mechanistic explanation of differences in the sensitivity of Daphnia magna and Gammarus pulex
Kretzschmar_2012_Nature_483_341A petunia ABC protein controls strigolactone-dependent symbiotic signalling and branching
Krishnan_2012_J.Neural.Transm.(Vienna)_119_345A comparison of neurotoxicity in cerebellum produced by dermal application of chlorpyrifos in young and adult mice
Kristoff_2012_Aquat.Toxicol_112-113_19In vivo studies on inhibition and recovery of B-esterase activities in Biomphalaria glabrata exposed to azinphos-methyl: analysis of enzyme, substrate and tissue dependence
Kroger_2012_Am.J.Geriatr.Pharmacother_10_373Use of rivastigmine or galantamine and risk of adverse cardiac events: a database study from the Netherlands
Kroger_2012_Proc.Natl.Acad.Sci.U.S.A_109_E1277The transcriptional landscape and small RNAs of Salmonella enterica serovar Typhimurium
Kroker_2012_Neuropharmacol_62_1964Inhibition of acetylcholinesterase and phosphodiesterase-9A has differential effects on hippocampal early and late LTP
Kruse_2012_Nature_482_552Structure and dynamics of the M3 muscarinic acetylcholine receptor
Krzeslak_2012_FEMS.Microbiol.Lett_329_146Lipase A gene transcription in Pseudomonas alcaligenes is under control of RNA polymerase sigma54 and response regulator LipR
Kubo_2012_J.Cardiovasc.Pharmacol_60_310Influences of Donepezil on Cardiovascular System-Possible Therapeutic Benefits for Heart Failure-DOnepezil Cardiac TEst Registry (DOCTER) Study
Kucinski_2012_Schizophr.Res_136_82alpha7 neuronal nicotinic receptor agonist (TC-7020) reverses increased striatal dopamine release during acoustic PPI testing in a transgenic mouse model of schizophrenia
Kudavalli_2012_J.Org.Chem_77_563Hyperaromatic stabilization of arenium ions: acid-catalyzed dehydration of 2-substituted 1,2-dihydro-1-naphthols
Kuhse_2012_J.Biol.Chem_287_30952Phosphorylation of gephyrin in hippocampal neurons by cyclin-dependent kinase CDK5 at Ser-270 is dependent on collybistin
Kumar_2012_Biosci.Biotechnol.Biochem_76_1518Cognitive enhancing effects of alpha asarone in amnesic mice by influencing cholinergic and antioxidant defense mechanisms
Kumar_2012_J.Bacteriol_194_3286Genome sequence of the nitroaromatic compound-degrading Bacterium Burkholderia sp. strain SJ98
Kumar_2012_J.Bacteriol_194_3731Genome sequence of the halotolerant bacterium Imtechella halotolerans K1T
Kumar_2012_J.Ethnopharmacol_140_151Safety evaluation of an Ayurvedic medicine, Arogyavardhini vati on brain, liver and kidney in rats
Kumar_2012_Pharmacol.Rep_64_1291Drug therapy in autism: a present and future perspective
Kumari_2012_Biotechnol.Lett_34_1733Extracellular expression and characterization of thermostable lipases, LIP8, LIP14 and LIP18, from Yarrowia lipolytica
Kumari_2012_Cell.Metab_15_691Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase
Kumari_2012_World.J.Microbiol.Biotechnol_28_3103Comparative biochemical characterization and in silico analysis of novel lipases Lip11 and Lip12 with Lip2 from Yarrowia lipolytica
Kunigal_2012_Mol.Cancer_11_24Nicotine, IFN-gamma and retinoic acid mediated induction of MUC4 in pancreatic cancer requires E2F1 and STAT-1 transcription factors and utilize different signaling cascades
Kuo_2012_Bioprocess.Biosyst.Eng_35_1137Lipase catalyzed acetylation of 3,5,4'-trihydroxystilbene: optimization and kinetics study
Kuo_2012_Eur.J.Pharmacol_692_10Alpha-lipoic acid induces adipose triglyceride lipase expression and decreases intracellular lipid accumulation in HepG2 cells
Kuo_2012_Int.J.Mol.Sci_13_11694High yield of wax ester synthesized from cetyl alcohol and octanoic acid by lipozyme RMIM and Novozym 435
Kurdoglu_2012_Clin.Exp.Hypertens_34_493Evaluation of the relationship between adenosine deaminase, myeloperoxidase, cholinesterase, preeclampsia severity, and neonatal outcomes
Kurita_2012_Anal.Chem_84_1799Determination of DNA methylation using electrochemiluminescence with surface accumulable coreactant
Kurkova_2012_Biochemistry.(Mosc)_77_1139Creation of catalytic antibodies metabolizing organophosphate compounds
Kuznetsova_2012_Mol.Neurobiol_45_488A new trend in the experimental methodology for the analysis of the thioflavin T binding to amyloid fibrils
Kwak_2012_J.Bacteriol_194_4432Complete genome sequence of the endophytic bacterium Burkholderia sp. strain KJ006
Kwon_2012_Insect.Biochem.Mol.Biol_42_212The overexpression of acetylcholinesterase compensates for the reduced catalytic activity caused by resistance-conferring mutations in Tetranychus urticae
Kwon_2012_J.Asia.Pac.Entomol_15_635Monitoring of carbamate and organophosphate resistance levels in Nilaparvata lugens based on bioassay and quantitative sequencing
Kwon_2012_Nat.Neurosci_15_1667Neuroligin-1-dependent competition regulates cortical synaptogenesis and synapse number
Kwon_2012_Pestic.Biochem.Physiol_103_94Cloning of the acetylcholinesterase 1 gene and identification of point mutations putatively associated with carbofuran resistance in Nilaparvata lugens
Kycia_2012_Anal.Chim.Acta_737_45Non-contact detection of chemical warfare simulant triethyl phosphate using PM-IRRAS
Kyle_2012_J.Bacteriol_194_1885Escherichia coli serotype O55:H7 diversity supports parallel acquisition of bacteriophage at Shiga toxin phage insertion sites during evolution of the O157:H7 lineage
Lackner_2012_Fungal.Genet.Biol_49_996Genome mining reveals the evolutionary origin and biosynthetic potential of basidiomycete polyketide synthases
Lagas_2012_Mol.Pharmacol_82_636P-glycoprotein, multidrug-resistance associated protein 2, cyp3a, and carboxylesterase affect the oral availability and metabolism of vinorelbine
Lai_2012_J.Bacteriol_194_6674Complete genome sequence of Alcanivorax dieselolei type strain B5
Lai_2012_J.Bacteriol_194_6677Complete genome sequence of the pyrene-degrading bacterium Cycloclasticus sp. strain P1
Lai_2012_J.Bacteriol_194_6936Genome sequence of an alkane-degrading bacterium, Alcanivorax pacificus type strain W11-5, isolated from deep sea sediment
Lai_2012_J.Bacteriol_194_6937Genome sequence of Gallaecimonas xiamenensis type strain 3-C-1
Lai_2012_J.Bacteriol_194_6938Genome sequence of Idiomarina xiamenensis type strain 10-D-4
Lai_2012_J.Bacteriol_194_6942Genome sequence of Oceanibaculum indicum type strain P24
Lai_2012_J.Bacteriol_194_6956Genome sequence of Thalassospira profundimaris type strain WP0211
Lai_2012_J.Bacteriol_194_6957Genome sequence of Thalassospira xiamenensis type strain M-5
Lai_2012_J.Bacteriol_194_6958Genome sequence of Nitratireductor pacificus type strain pht-3B
Lai_2012_J.Bacteriol_194_6972Genome sequence of the alkane-degrading bacterium Alcanivorax hongdengensis type strain A-11-3
Lai_2012_J.Bacteriol_194_6973Genome sequence of Galbibacter marinum type strain ck-I2-15
Lai_2012_J.Bacteriol_194_6990Genome sequence of Nitratireductor indicus type strain C115
Lai_2012_J.Bacteriol_194_6991Genome sequence of Bacillus sp. strain HYC-10, isolated from intestinal tract contents from a marine fish (Mugil cephalus)
Lai_2012_Science_336_1129Structure of a 16-nm cage designed by using protein oligomers.
Lam_2012_Bioorg.Med.Chem.Lett_22_6628Structure-based design of pyridopyrimidinediones as dipeptidyl peptidase IV inhibitors
Lam_2012_J.Bacteriol_194_2334Comparative analysis of the first complete Enterococcus faecium genome
Lameh_2012_Naunyn.Schmiedebergs.Arch.Pharmacol_385_313Discovery of potential antipsychotic agents possessing pro-cognitive properties
Lamotte d'Incamps_2012_J.Neurosci_32_8413Mechanisms shaping the slow nicotinic synaptic current at the motoneuron-renshaw cell synapse
Lampon_2012_Ann.Hepatol_11_356Association between butyrylcholinesterase activity and low-grade systemic inflammation
Lanciego_2012_Brain.Struct.Funct_217_613The basal ganglia and thalamus of the long-tailed macaque in stereotaxic coordinates. A template atlas based on coronal, sagittal and horizontal brain sections
Lang_2012_Curr.Drug.Targets_13_495Can acetylcholinesterase serve as a target for developing more selective insecticides?
Lansdell_2012_BMC.Neurosci_13_73The Drosophila nicotinic acetylcholine receptor subunits Dalpha5 and Dalpha7 form functional homomeric and heteromeric ion channels
Lape_2012_J.Neurosci_32_1336The alpha1K276E startle disease mutation reveals multiple intermediate states in the gating of glycine receptors
Laplante_2012_Neuropharmacol_63_1075Cholinergic depletion in nucleus accumbens impairs mesocortical dopamine activation and cognitive function in rats
Lasa_2012_J.Nutr.Biochem_23_379Resveratrol regulates lipolysis via adipose triglyceride lipase
Lasonder_2012_Microbes.Infect_14_811Insights into the Plasmodium falciparum schizont phospho-proteome
Lasserson_2012_BMJ_344_e1213The role of dipeptidyl peptidase-4 inhibitors
Lau_2012_AMB.Express_2_41Revelation of the ability of Burkholderia sp. USM (JCM 15050) PHA synthase to polymerize 4-hydroxybutyrate monomer
Laurie_2012_Plant.Cell_24_1733Genome comparison of barley and maize smut fungi reveals targeted loss of RNA silencing components and species-specific presence of transposable elements
Lavzin_2012_Nature_490_397Nonlinear dendritic processing determines angular tuning of barrel cortex neurons in vivo
Lazarevic-Pasti_2012_Pestic.Biochem.Physiol_104_236Indirect electrochemical oxidation of organophosphorous pesticides for efficient detection via acetylcholinesterase test
Lazaridis_2012_Ann.N.Y.Acad.Sci_1275_7Antigen-specific apheresis of autoantibodies in myasthenia gravis
Le Bars_2012_J.Bacteriol_194_3537Complete genome sequence of the strong mutator Salmonella enterica subsp. enterica serotype Heidelberg strain B182
Le Couteur_2012_Australas.J.Ageing_31_164Adherence, persistence and continuation with cholinesterase inhibitors in Alzheimer's disease
LeVine_2012_Biochemistry_51_307Dihydroxybenzoic acid isomers differentially dissociate soluble biotinyl-Abeta(1-42) oligomers
Leach_2012_Handb.Exp.Pharmacol_208_29Structure-function studies of muscarinic acetylcholine receptors
Lebda_2012_Neurotoxicol_33_98Neurohepatic toxicity of subacute manganese chloride exposure and potential chemoprotective effects of lycopene
Lechat_2012_J.Exp.Bot_63_5311PrCYP707A1, an ABA catabolic gene, is a key component of Phelipanche ramosa seed germination in response to the strigolactone analogue GR24
Lecrux_2012_J.Cereb.Blood.Flow.Metab_32_896Pyramidal cells and cytochrome P450 epoxygenase products in the neurovascular coupling response to basal forebrain cholinergic input
Lee_2012_Appl.Environ.Microbiol_78_4959Novel metagenome-derived, cold-adapted alkaline phospholipase with superior lipase activity as an intermediate between phospholipase and lipase
Lee_2012_Biochem.Biophys.Res.Commun_426_492Sulforaphane induced adipolysis via hormone sensitive lipase activation, regulated by AMPK signaling pathway
Lee_2012_Bioprocess.Biosyst.Eng_35_105Improved high-pressure enzymatic biodiesel batch synthesis in near-critical carbon dioxide
Lee_2012_J.Bacteriol_194_4150Genome sequence of Herbaspirillum sp. strain GW103, a plant growth-promoting bacterium
Lee_2012_J.Bacteriol_194_4766Genome sequence of Lactobacillus mucosae LM1, isolated from piglet feces
Lee_2012_J.Bacteriol_194_544Complete genome sequence of the BTEX-degrading bacterium Pseudoxanthomonas spadix BD-a59
Lee_2012_J.Bacteriol_194_5711Draft genome sequence of Weissella koreensis KCTC 3621T
Lee_2012_J.Bacteriol_194_6640Draft Genome sequence of Escherichia coli AI27, a porcine isolate belonging to phylogenetic group B1
Lee_2012_J.Bacteriol_194_6695Draft genome sequence of Salimicrobium sp. strain MJ3, isolated from Myulchi-Jeot, Korean fermented seafood
Lee_2012_J.Bacteriol_194_6934Draft genome sequence of the biocontrol bacterium Bacillus amyloliquefaciens strain M27
Lee_2012_J.Neurosci_32_16296Learning-related synaptic growth mediated by internalization of Aplysia cell adhesion molecule is controlled by membrane phosphatidylinositol 4,5-bisphosphate synthetic pathway
Lee_2012_Life.Sci_91_1058Nicotine and pathological angiogenesis
Lee_2012_Neurochem.Res_37_1499The acetylcholinesterase inhibitors competitively inhibited an acetyl L-carnitine transport through the blood-brain barrier
Lee_2012_Plant.J_72_411Benzoylation and sinapoylation of glucosinolate R-groups in Arabidopsis
Lee_2012_Proc.Natl.Acad.Sci.U.S.A_109_14200A cellular model of memory reconsolidation involves reactivation-induced destabilization and restabilization at the sensorimotor synapse in Aplysia
Lee_2012_Proteins_80_421Identifying continuous pores in protein structures with PROPORES by computational repositioning of gating residues
Leelavathi_2012_Clin.Ter_163_31Pisa syndrome secondary to rivastigmine: a case report
Legler_2012_Arch.Biochem.Biophys_528_7A role for His-160 in peroxide inhibition of S. cerevisiae S-formylglutathione hydrolase: evidence for an oxidation sensitive motif
Lemak_2012_Biochem.J_445_193Structure and activity of the cold-active and anion-activated carboxyl esterase OLEI01171 from the oil-degrading marine bacterium Oleispira antarctica
Lenz_2012_Psychopharmacology.(Berl)_220_97The scopolamine model as a pharmacodynamic marker in early drug development
Leonard_2012_Stand.Genomic.Sci_7_271Complete genome sequence of Liberibacter crescens BT-1
Levin_2012_Nicotine.Tob.Res_14_299Varenicline dose dependently enhances responding for nonpharmacological reinforcers and attenuates the reinforcement-enhancing effects of nicotine
Levin_2012_Zh.Nevrol.Psikhiatr.Im.S.S.Korsakova_112_3[Dementia with Lewy bodies.]
Levisson_2012_Proteins_80_1545Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima
Levy-Barazany_2012_J.Neuroinflammation_9_120Expression of scavenger receptor A on antigen presenting cells is important for CD4+ T-cells proliferation in EAE mouse model
Levy_2012_Drugs.Aging_29_167Does pharmacological treatment of neuropsychiatric symptoms in Alzheimer's disease relieve caregiver burden?
Li_2012_Analyst_137_3160Ionic liquid-functionalized graphene for fabricating an amperometric acetylcholinesterase biosensor
Li_2012_Appl.Microbiol.Biotechnol_94_1553An isofenphos-methyl hydrolase (Imh) capable of hydrolyzing the P-O-Z moiety of organophosphorus pesticides containing an aryl or heterocyclic group
Li_2012_Biol.Trace.Elem.Res_150_221BmNPV Resistance of Silkworm Larvae Resulting from the Ingestion of TiO(2) Nanoparticles
Li_2012_Biotechnol.Lett_34_153Resolution of 2-nitroalcohols by Burkholderia cepacia lipase-catalyzed enantioselective acylation
Li_2012_Chem.Pharm.Bull.(Tokyo)_60_1448New Alkaloids from Lycopodium japonicum
Li_2012_Dev.Dyn_241_1562Differential regulation of axonal growth and neuromuscular junction assembly by HGF/c-Met signaling
Li_2012_Ecotoxicology_21_353Single and combined effects of selected pharmaceuticals at sublethal concentrations on multiple biomarkers in Carassius auratus
Li_2012_Environ.Toxicol.Chem_31_843Survival, mobility, and membrane-bound enzyme activities of freshwater planarian, Dugesia japonica, exposed to synthetic and natural surfactants
Li_2012_Eukaryot.Cell_11_1451Rapid Triacylglycerol Turnover in Chlamydomonas reinhardtii Requires a Lipase with Broad Substrate Specificity
Li_2012_Exp.Ther.Med_3_269Steady and fluctuant methods of inhibition of acetylcholinesterase differentially regulate neurotrophic factors in the hippocampus of juvenile mice
Li_2012_J.Anim.Sci_90_4346Alternative splicing and developmental and hormonal regulation of porcine comparative gene identification-58 (CGI-58) mRNA
Li_2012_J.Bacteriol_194_1243Genome sequence of the highly efficient arsenite-oxidizing bacterium Achromobacter arsenitoxydans SY8
Li_2012_J.Bacteriol_194_1267Draft genome sequence of Sinorhizobium meliloti CCNWSX0020, a nitrogen-fixing symbiont with copper tolerance capability isolated from lead-zinc mine tailings
Li_2012_J.Bacteriol_194_2117Genome sequence of Paenibacillus sp. strain Aloe-11, an endophytic bacterium with broad antimicrobial activity and intestinal colonization ability
Li_2012_J.Bacteriol_194_4473Genome sequence of the moderately halotolerant, arsenite-oxidizing bacterium Pseudomonas stutzeri TS44
Li_2012_J.Bacteriol_194_5154Complete genome sequence of the naphthalene-degrading Pseudomonas putida strain ND6
Li_2012_J.Neurooncol_108_385t-AUCB, an improved sEH inhibitor, suppresses human glioblastoma cell growth by activating NF-kappaB-p65
Li_2012_J.Neurooncol_110_187The apoptosis-resistance in t-AUCB-treated glioblastoma cells depends on activation of Hsp27
Li_2012_J.Toxicol.Environ.Health.B.Crit.Rev_15_109Evaluation of epidemiology and animal data for risk assessment: chlorpyrifos developmental neurobehavioral outcomes
Li_2012_Mar.Drugs_10_234Antibacterial bisabolane-type sesquiterpenoids from the sponge-derived fungus Aspergillus sp
Li_2012_Mol.Biol.Cell_23_4109Regulation of axonal growth and neuromuscular junction formation by neuronal phosphatase and tensin homologue signaling
Li_2012_Mol.Med.Rep_6_1450Expression of APP, BACE1, AChE and ChAT in an AD model in rats and the effect of donepezil hydrochloride treatment
Li_2012_Molecules_17_716Evaluation of the immunity activity of glycyrrhizin in AR mice
Li_2012_Neurochem.Int_61_1011Staurosporine-induced apoptosis presents with unexpected cholinergic effects in a differentiated neuroblastoma cell line
Li_2012_Neuroimage_60_1083Changes in regional cerebral blood flow and functional connectivity in the cholinergic pathway associated with cognitive performance in subjects with mild Alzheimer's disease after 12-week donepezil treatment
Li_2012_PLoS.One_7_e44759Reciprocal regulation of axonal Filopodia and outgrowth during neuromuscular junction development
Li_2012_PLoS.One_7_e46881Role of the NC-loop in catalytic activity and stability in lipase from Fervidobacterium changbaicum
Li_2012_Pestic.Biochem.Physiol_102_198Molecular characterization of two acetylcholinesterase genes from the brown planthopper, Nilaparvata lugens (Hemiptera: Delphacidae)
Lian_2012_Circ.Res_111_982Ces3/TGH deficiency improves dyslipidemia and reduces atherosclerosis in Ldlr(-/-) mice
Lian_2012_Hepatology_56_2154Liver specific inactivation of carboxylesterase 3/triacylglycerol hydrolase decreases blood lipids without causing severe steatosis in mice
Liang_2012_PLoS.One_7_e45346Pan-genomic analysis provides insights into the genomic variation and evolution of Salmonella Paratyphi A
Liao_2012_Anal.Chem_84_45Acetylcholinesterase liquid crystal biosensor based on modulated growth of gold nanoparticles for amplified detection of acetylcholine and inhibitor
Liao_2012_J.Bacteriol_194_5454Complete genome sequence of Klebsiella oxytoca E718, a New Delhi metallo-beta-lactamase-1-producing nosocomial strain
Licursi_2012_Eur.J.Neurosci_35_691Lack of dystrophin in mdx mice modulates the expression of genes involved in neuron survival and differentiation
Liddelow_2012_PLoS.One_7_e33554Molecular characterisation of transport mechanisms at the developing mouse blood-CSF interface: a transcriptome approach
Liew_2012_J.Biol.Chem_287_23203Crystal structure of the acyltransferase domain of the iterative polyketide synthase in enediyne biosynthesis
Lifshitz_2012_Neurobiol.Aging_33_432 e1Immunotherapy of cerebrovascular amyloidosis in a transgenic mouse model
Lim_2012_J.Bacteriol_194_896Complete genome sequence of the fenitrothion-degrading Burkholderia sp. strain YI23
Lin_2012_Chem.Res.Toxicol_25_1462Synthesis and evaluation of a new series of tri-, di-, and mono-N-alkylcarbamylphloroglucinols as bulky inhibitors of acetylcholinesterase
Lin_2012_Expert.Opin.Pharmacother_13_841Pharmacotherapy of obstructive sleep apnea
Lin_2012_Int.J.Dev.Neurosci_30_113Differential long term effects of early diisopropylfluorophosphate exposure in Balb/C and C57Bl/J6 mice
Lin_2012_J.Bacteriol_194_199Draft genome sequence of Halomonas sp. strain HAL1, a moderately halophilic arsenite-oxidizing bacterium isolated from gold-mine soil
Lin_2012_J.Bacteriol_194_6316Complete genome sequence of Klebsiella pneumoniae 1084, a hypermucoviscosity-negative K1 clinical strain
Lin_2012_Mol.Pharmacol_82_843Identification and pharmacological characterization of multiple allosteric binding sites on the free fatty acid 1 receptor
Lin_2012_Protein.Sci_21_1344Synthesis and evaluation of a new series of tri-, di-, and mono-N-alkylcarbamylphloroglucinols as conformationally constrained inhibitors of cholesterol esterase
Linardaki_2012_Food.Chem.Toxicol_52C_163Investigation of the neuroprotective action of saffron (Crocus sativus L.) in aluminum-exposed adult mice through behavioral and neurobiochemical assessment
Lindberg_2012_Ugeskr.Laeger_174_2331[Why choose another cholinesterase inhibitor than donepezil?]
Linder_2012_J.Comput.Aided.Mol.Des_26_1079Computational design of a Diels-Alderase from a thermophilic esterase: the importance of dynamics
Lindholm-Perry_2012_Anim.Genet_43_216A region on BTA14 that includes the positional candidate genes LYPLA1, XKR4 and TMEM68 is associated with feed intake and growth phenotypes in cattle(1)
Lindovsky_2012_Eur.J.Pharmacol_688_22Effect of tissue-specific acetylcholinesterase inhibitor C-547 on alpha3beta4 and alphabetaepsilondelta acetylcholine receptors in COS cells
Lines_2012_Nephrol.Dial.Transplant_27_2425A predictive algorithm for the management of anaemia in haemodialysis patients based on ESA pharmacodynamics: better results for less work
Liou_2012_J.Bacteriol_194_6974Genome sequence of Acinetobacter baumannii TYTH-1
Lipovsek_2012_Proc.Natl.Acad.Sci.U.S.A_109_4308Phylogenetic differences in calcium permeability of the auditory hair cell cholinergic nicotinic receptor
Lippold_2012_Plant.Cell_24_2001Fatty acid phytyl ester synthesis in chloroplasts of Arabidopsis
Lira_2012_J.Bacteriol_194_3563Whole-genome sequence of Stenotrophomonas maltophilia D457, a clinical isolate and a model strain
Liska_2012_Hepatogastroenterology_59_235Inhibition of transforming growth factor beta-1 augments liver regeneration after partial portal vein ligation in a porcine experimental model
Liska_2012_In.Vivo_26_683Immediately preoperative use of biological therapy does not influence liver regeneration after large resection--porcine experimental model with monoclonal antibody against epidermal growth factor
Liu_2012_ACS.Appl.Mater.Interfaces_4_5169Preparation of Superparamagnetic Fe(3)O(4)@Alginate/Chitosan Nanospheres for Candida rugosa lipase Immobilization and Utilization of Layer-by-Layer Assembly to Enhance the Stability of Immobilized Lipase
Liu_2012_ACS.Nano_6_11080Quantum Dot Targeting with Lipoic Acid Ligase and HaloTag for Single-Molecule Imaging on Living Cells
Liu_2012_Adv.Healthc.Mater_1_90A highly sensitive gold-nanoparticle-based assay for acetylcholinesterase in cerebrospinal fluid of transgenic mice with Alzheimer's disease
Liu_2012_Am.J.Chin.Med_40_993The memory-ameliorating effects of Artemisia princeps var. orientalis against cholinergic dysfunction in mice
Liu_2012_Anal.Chem_84_4185A highly sensitive, dual-readout assay based on gold nanoparticles for organophosphorus and carbamate pesticides
Liu_2012_BMC.Genomics_13_595Efficient assembly and annotation of the transcriptome of catfish by RNA-Seq analysis of a doubled haploid homozygote
Liu_2012_BMC.Neurosci_13_155Functional alpha7beta2 nicotinic acetylcholine receptors expressed in hippocampal interneurons exhibit high sensitivity to pathological level of amyloid beta peptides
Liu_2012_Biochem.Biophys.Res.Commun_423_55Changes of calcium channel mRNA, protein and current in NG108-15 cells after cell differentiation
Liu_2012_Biochem.Biophys.Res.Commun_424_285Molecular basis for substrate selectivity of a mono- and diacylglycerol lipase from Malassezia globosa
Liu_2012_Biomaterials_33_2240An oligopeptide ligand-mediated therapeutic gene nanocomplex for liver cancer-targeted therapy
Liu_2012_Chembiochem_13_2082Rapid development of a potent photo-triggered inhibitor of the serine hydrolase RBBP9
Liu_2012_Curr.Med.Chem_19_3982Recent advances in non-peptidomimetic dipeptidyl peptidase 4 inhibitors: medicinal chemistry and preclinical aspects
Liu_2012_Ecotoxicol.Environ.Saf_80_118Altered quantities and in vivo activities of cholinesterase from Daphnia magna in sub-lethal exposure to organophosphorus insecticides
Liu_2012_Front.Microbiol_3_185Complete Genome of Ignavibacterium album, a Metabolically Versatile, Flagellated, Facultative Anaerobe from the Phylum Chlorobi
Liu_2012_J.Bacteriol_194_1841Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae HS11286, a multidrug-resistant strain isolated from human sputum
Liu_2012_J.Bacteriol_194_5965Complete genome sequence of the endophytic Enterobacter cloacae subsp. cloacae strain ENHKU01
Liu_2012_J.Bacteriol_194_6321Complete genome sequence of Brucella melitensis biovar 3 strain NI, isolated from an aborted bovine fetus
Liu_2012_J.Biol.Chem_287_44406Purification and characterization of a novel galloyltransferase involved in catechin galloylation in the tea plant (Camellia sinensis)
Liu_2012_J.Biomater.Sci.Polym.Ed_23_1355Enzyme-catalyzed degradation of biodegradable polymers derived from trimethylene carbonate and glycolide by lipases from Candida antarctica and Hog pancreas
Liu_2012_J.Chem.Theory.Comput_8_1426Reaction Pathway and Free Energy Profile for Cocaine Hydrolase-Catalyzed Hydrolysis of (-)-Cocaine
Liu_2012_J.Neuroinflammation_9_98alpha7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation
Liu_2012_J.Pharmacol.Exp.Ther_341_725Attenuation of cisplatin-induced renal injury by inhibition of soluble epoxide hydrolase involves nuclear factor kappaB signaling
Liu_2012_Microb.Cell.Fact_11_25Characterization of a thermostable beta-glucosidase from Aspergillus fumigatus Z5, and its functional expression in Pichia pastoris X33
Liu_2012_Microbiol.Res_167_452Cloning, expression and characterization of a lipase gene from the Candida antarctica ZJB09193 and its application in biosynthesis of vitamin A esters
Liu_2012_Mol.Pharmacol_81_541Nicotine persistently activates ventral tegmental area dopaminergic neurons via nicotinic acetylcholine receptors containing alpha4 and alpha6 subunits
Liu_2012_Neuropharmacol_62_2515Galantamine attenuates the heroin seeking behaviors induced by cues after prolonged withdrawal in rats
Liu_2012_Nucleic.Acids.Res_40_4530A novel non-homologous recombination-mediated mechanism for Escherichia coli unilateral flagellar phase variation
Liu_2012_PLoS.One_7_e39165Inhibition of soluble epoxide hydrolase attenuates high-fat-diet-induced hepatic steatosis by reduced systemic inflammatory status in mice
Liu_2012_PLoS.One_7_e43821Systematic review and meta-analysis of the relationship between EPHX1 polymorphisms and colorectal cancer risk
Liu_2012_PLoS.One_7_e44044Induction of histiocytic sarcoma in mouse skeletal muscle
Liu_2012_Pharmacol.Biochem.Behav_103_474Protective effects of nizofenone administration on the cognitive impairments induced by chronic restraint stress in mice
Liu_2012_Twin.Res.Hum.Genet_15_126Clinical and genetic analysis of a compound heterozygous mutation in the thyroglobulin gene in a Chinese twin family with congenital goiter and hypothyroidism
Liu_2012_Zhongguo.Zhong.Yao.Za.Zhi_37_2439[Effect of Kaixin San on learning and memory in chronic stress depression model rats]
Liyasova_2012_Chem.Res.Toxicol_25_1752Cresyl saligenin phosphate, an organophosphorus toxicant, makes covalent adducts with histidine, lysine, and tyrosine residues of human serum albumin
Lo_2012_J.Am.Chem.Soc_134_4709Two separate gene clusters encode the biosynthetic pathway for the meroterpenoids austinol and dehydroaustinol in Aspergillus nidulans
Loizzo_2012_J.Sci.Food.Agric_92_2960Evaluation of Citrus aurantifolia peel and leaves extracts for their chemical composition, antioxidant and anti-cholinesterase activities
Lommer_2012_Genome.Biol_13_R66Genome and low-iron response of an oceanic diatom adapted to chronic iron limitation
Lonjers_2012_J.Bacteriol_194_965Identification of a new gene required for the biosynthesis of rhodoquinone in Rhodospirillum rubrum
Loper_2012_PLoS.Genet_8_E1002784Comparative genomics of plant-associated Pseudomonas spp.: insights into diversity and inheritance of traits involved in multitrophic interactions
Lopes_2012_J.Bacteriol_194_3567Complete genome sequence of Corynebacterium pseudotuberculosis strain Cp267, isolated from a llama
Lopez-Gallego_2012_Biochemistry_51_7028Altering the interfacial activation mechanism of a lipase by solid-phase selective chemical modification
Lopez-Huerta_2012_J.Neurophysiol_108_1032Presynaptic modulation by somatostatin in the rat neostriatum is altered in a model of parkinsonism
Lopez-Perez_2012_Sci.Rep_2_696Genomes of surface isolates of Alteromonas macleodii: the life of a widespread marine opportunistic copiotroph
Lopez-Pousa_2012_Am.J.Alzheimers.Dis.Other.Demen_27_260Use of antidementia drugs in frontotemporal lobar degeneration
Lopez-Pousa_2012_Drugs.Aging_29_733Consumption of pharmaceuticals in primary non-Alzheimer's degenerative dementias : a cross-sectional study by the Registry of Dementias of Girona (ReDeGi)
Lord_2012_Adipocyte_1_123Distinct roles for alpha-beta hydrolase domain 5 (ABHD5/CGI-58) and adipose triglyceride lipase (ATGL/PNPLA2) in lipid metabolism and signaling
Lord_2012_Diabetes_61_355CGI-58/ABHD5-derived signaling lipids regulate systemic inflammation and insulin action
Lorenzoni_2012_Pediatr.Neurol_46_141Congenital myasthenic syndrome: a brief review
Lorke_2012_CNS.Neurol.Disord.Drug.Targets_11_1052Acetylcholinesterase Inhibitors as Pretreatment before Acute Exposure to Organophosphates: Assessment Using Methyl-paraoxon
Lotfipour_2012_Neuropsychopharmacology_37_1738A single administration of low-dose varenicline saturates alpha4beta2* nicotinic acetylcholine receptors in the human brain
Lotti_2012_Mol.Biosyst_8_105Mutual effects of disorder and order in fusion proteins between intrinsically disordered domains and fluorescent proteins
Lou_2012_Neurosci_223_225Intranasal administration of TAT-haFGF(14-154) attenuates disease progression in a mouse model of Alzheimer's disease
Louis_2012_Eur.J.Neurosci_36_3438Amelalpha8 subunit knockdown in the mushroom body vertical lobes impairs olfactory retrieval in the honeybee, Apis mellifera
Louis_2012_G3.(Bethesda)_2_299Pichia sorbitophila, an Interspecies Yeast Hybrid, Reveals Early Steps of Genome Resolution After Polyploidization
Lovera_2012_Curr.Neurol.Neurosci.Rep_12_618Cognitive impairment in multiple sclerosis
Lozada_2012_J.Neurosci_32_7651Glutamatergic synapse formation is promoted by alpha7-containing nicotinic acetylcholine receptors
Lozada_2012_J.Neurosci_32_8391Induction of dendritic spines by beta2-containing nicotinic receptors
Lozano_2012_ChemSusChem_5_790Immobilised lipase on structured supports containing covalently attached ionic liquids for the continuous synthesis of biodiesel in scCO2
Lu_2012_Chirality_24_481Enantioselective toxicological response of the green alga Scenedesmus obliquus to isocarbophos
Lu_2012_PLoS.One_7_e32288Genome organization, phylogenies, expression patterns, and three-dimensional protein models of two acetylcholinesterase genes from the red flour beetle
Lu_2012_PLoS.Pathog_8_E1002663A GATA transcription factor recruits Hda1 in response to reduced Tor1 signaling to establish a hyphal chromatin state in Candida albicans
Lu_2012_Sci.Rep_2_288Cholinergic and non-cholinergic functions of two acetylcholinesterase genes revealed by gene-silencing in Tribolium castaneum
Lucas-Elio_2012_Stand.Genomic.Sci_7_31Complete genome sequence of Marinomonas posidonica type strain (IVIA-Po-181(T))
Lucet_2012_Future.Med.Chem_4_2295Plasmodium kinases as targets for new-generation antimalarials
Lucia_2012_Sci.Total.Environ_423_73Insight on trace element detoxification in the Black-tailed Godwit (Limosa limosa) through genetic, enzymatic and metallothionein analyses
Luger_2012_Future.Med.Chem_4_1399Electron density study of the anti-Alzheimer's disease drug donepezil from conventional x-ray data and invariom database application
Lugokenski_2012_Basic.Clin.Pharmacol.Toxicol_111_362Effect of different oximes on rat and human cholinesterases inhibited by methamidophos: a comparative in vitro and in silico study
Luk_2012_Febs.J_279_3229N-linked glycosylation of dimeric acetylcholinesterase in erythrocytes is essential for enzyme maturation and membrane targeting
Lukiw_2012_Expert.Opin.Emerg.Drugs_17_43Amyloid beta (Abeta) peptide modulators and other current treatment strategies for Alzheimer's disease (AD)
Lundby_2012_Nat.Commun_3_876Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues
Luning-Koster_2012_Ned.Tijdschr.Geneeskd_156_A5323[Summary of Dutch College of General Practitioners' (NHG) practice guideline 'Dementia']
Luo_2012_Fungal.Genet.Biol_49_123Ribosomal biosynthesis of alpha-amanitin in Galerina marginata
Luo_2012_J.Bacteriol_194_907Genome sequence of benzo(a)pyrene-degrading bacterium Novosphingobium pentaromativorans US6-1
Luo_2012_Yao.Xue.Xue.Bao_47_916[Design, synthesis and evaluation of tacrine-methoxybenzene hybrids as cholinesterases inhibitors]
Luttge_2012_Plant.Biol.(Stuttg)_14_865Modularity and emergence: biology's challenge in understanding life
Lv_2012_J.Bacteriol_194_742Genome sequence of Corynebacterium glutamicum ATCC 14067, which provides insight into amino acid biosynthesis in coryneform bacteria
Lynch_2012_Genes.Brain.Behav_11_222The mate choice brain: comparing gene profiles between female choice and male coercive poeciliids
Ma_2012_J.Bacteriol_194_2777Complete genome sequence of Paenibacillus mucilaginosus 3016, a bacterium functional as microbial fertilizer
Ma_2012_Zhonghua.Nei.Ke.Za.Zhi_51_618[A noninvasive diagnostic model of liver fibrosis using serum markers in primary biliary cirrhosis]
Maas_2012_J.Neurosci_32_11095Formation of Golgi-derived active zone precursor vesicles
Macauley_2012_Ann.Neurol_71_797Synergistic effects of central nervous system-directed gene therapy and bone marrow transplantation in the murine model of infantile neuronal ceroid lipofuscinosis
Macdonald_2012_Biochemistry_51_7046Probing the peripheral site of human butyrylcholinesterase
Machado_2012_Exp.Physiol_97_1186Autonomic nervous system modulation affects the inflammatory immune response in mice with acute Chagas disease
Machado_2012_J.Ethnopharmacol_143_158Rosmarinus officinalis L. hydroalcoholic extract, similar to fluoxetine, reverses depressive-like behavior without altering learning deficit in olfactory bulbectomized mice
Machado_2012_Pharmacol.Biochem.Behav_103_220Fluoxetine reverses depressive-like behaviors and increases hippocampal acetylcholinesterase activity induced by olfactory bulbectomy
Macijauskiene_2012_Medicina.(Kaunas)_45_1Dementia with lewy bodies: the principles of diagnostics, treatment, and management
Macinnes_2012_J.Bacteriol_194_6686Complete genome sequence of Actinobacillus suis H91-0380, a virulent serotype O2 strain
Mackey_2012_J.Neurosci_32_10226alpha6* nicotinic acetylcholine receptor expression and function in a visual salience circuit
Madhavilatha_2012_J.Bacteriol_194_4430Whole-genome sequences of two clinical isolates of Mycobacterium tuberculosis from Kerala, South India
Maeda-Yamamoto_2012_J.Sci.Food.Agric_92_2379Chemical analysis and acetylcholinesterase inhibitory effect of anthocyanin-rich red leaf tea (cv. Sunrouge)
Mahlke_2012_Nat.Prod.Res_26_2223In vitro toxicity, antiplatelet and acetylcholinesterase inhibition of Buddleja thyrsoides Lam. leaves
Maiga_2012_Toxicon_59_487G protein-coupled receptors, an unexploited animal toxin targets: Exploration of green mamba venom for novel drug candidates active against adrenoceptors
Mains_2012_Invest.Ophthalmol.Vis.Sci_53_4778Species variation in small molecule components of animal vitreous
Maiolino_2012_PLoS.One_7_e48171Lipoprotein-associated phospholipase A2 activity predicts cardiovascular events in high risk coronary artery disease patients
Makhaeva_2012_SAR.QSAR.Environ.Res_23_627Combined QSAR studies of inhibitor properties of O-phosphorylated oximes toward serine esterases involved in neurotoxicity, drug metabolism and Alzheimer's disease
Makoveichuk_2012_Biochem.Biophys.Res.Commun_425_138Inactivation of lipoprotein lipase occurs on the surface of THP-1 macrophages where oligomers of angiopoietin-like protein 4 are formed
Malek mohammadi_2012_Pestic.Biochem.Physiol_104_150Molecular diagnostic for detecting the acetylcholinesterase mutations in insecticide-resistant populations of Colorado potato beetle, Leptinotarsa decemlineata (Say)
Malhotra_2012_J.Bacteriol_194_5156Genome sequence of Acinetobacter sp. strain HA, isolated from the gut of the polyphagous insect pest Helicoverpa armigera
Malik_2012_Clin.Pharmacol.Ther_92_696Proarrhythmic safety of repeat doses of mirabegron in healthy subjects: a randomized, double-blind, placebo-, and active-controlled thorough QT study
Mamidala_2012_BMC.Genomics_13_6RNA-Seq and molecular docking reveal multi-level pesticide resistance in the bed bug
Man_2012_Evid.Based.Complement.Alternat.Med_2012_426215Systematic review on the efficacy and safety of herbal medicines for vascular dementia
Manco_2012_Protein.Pept.Lett_19_144Enzyme Promiscuity in the Hormone-Sensitive Lipase Family of Proteins
Mandal_2012_Biochem.Biophys.Res.Commun_417_43Brain oxidative stress: detection and mapping of anti-oxidant marker 'Glutathione' in different brain regions of healthy male/female, MCI and Alzheimer patients using non-invasive magnetic resonance spectroscopy
Mandour_2012_Int.J.Occup.Environ.Med_3_27Existence of insecticides in tap drinking surface and ground water in Dakahlyia Governorate, Egypt in 2011
Mangas_2012_Chem.Res.Toxicol_25_2393Phenylmethylsulfonyl fluoride, a potentiator of neuropathy, alters the interaction of organophosphorus compounds with soluble brain esterases
Mangas_2012_Toxicology_297_17NTE and non-NTE esterases in brain membrane: kinetic characterization with organophosphates
Mani_2012_Food.Chem.Toxicol_50_1036Protective effects of total alkaloidal extract from Murraya koenigii leaves on experimentally induced dementia
Manoochehri_2012_Curr.Neurol.Neurosci.Rep_12_528Diagnosis and management of behavioral issues in frontotemporal dementia
Mansfield_2012_J.Vet.Diagn.Invest_24_312Association between canine pancreatic-specific lipase and histologic exocrine pancreatic inflammation in dogs: assessing specificity
Mansour_2012_Drug.Chem.Toxicol_35_235Bioremediation of industrial pharmaceutical drugs
Mantione_2012_Future.Med.Chem_4_2217Allosteric modulators of alpha4beta2 nicotinic acetylcholine receptors: a new direction for antidepressant drug discovery
Manu_2012_Toxicol.Int_19_255A retrospective analysis of serial measurement of serum cholinesterase in acute poisoning with organophosphate compounds
Mao_2012_Bioorg.Med.Chem_20_5884O-Hydroxyl- or o-amino benzylamine-tacrine hybrids: multifunctional biometals chelators, antioxidants, and inhibitors of cholinesterase activity and amyloid-beta aggregation
Mao_2012_ISME.J_6_1613Genomic evidence of rapid, global-scale gene flow in a Sulfolobus species
Mappley_2012_BMC.Genomics_13_454Comparative genomics of Brachyspira pilosicoli strains: genome rearrangements, reductions and correlation of genetic compliment with phenotypic diversity
Maratha_2012_Neurochem.Res_37_2206Memory enhancing activity of naringin in unstressed and stressed mice: possible cholinergic and nitriergic modulation
Marcet-Houben_2012_BMC.Genomics_13_646Genome sequence of the necrotrophic fungus Penicillium digitatum, the main postharvest pathogen of citrus
Marchegiani_2012_J.Lipids_2012_601796Paraoxonase-1 55 LL Genotype Is Associated with No ST-Elevation Myocardial Infarction and with High Levels of Myoglobin
Marchetti_2012_Diabetologia_55_236High mobility group box 1 is a novel substrate of dipeptidyl peptidase-IV
Marchot_2012_Protein.Pept.Lett_19_130Hydrolase versus other functions of members of the alpha/beta-hydrolase fold superfamily of proteins
Marchot_2012_Protein.Pept.Lett_19_132Enzymatic activity and protein interactions in alpha/beta hydrolase fold proteins: moonlighting versus promiscuity
Marco-Ramell_2012_J.Proteomics_75_4399Proteomic analysis reveals oxidative stress response as the main adaptative physiological mechanism in cows under different production systems
Marcone_2012_J.Alzheimers.Dis_31_387[11C]-MP4A PET cholinergic measurements in amnestic mild cognitive impairment, probable Alzheimer's disease, and dementia with Lewy bodies: a Bayesian method and voxel-based analysis
Marei_2012_PLoS.One_7_e33542Gene expression profile of adult human olfactory bulb and embryonic neural stem cell suggests distinct signaling pathways and epigenetic control
Maretto_2012_Ecotoxicol.Environ.Saf_80_203Acute exposure to the insecticide O,S-dimethyl phosphoramidothioate (methamidophos) leads to impairment of cardiovascular reflexes in rats
Marfella_2012_Exp.Diabetes.Res_2012_892706Dipeptidyl peptidase 4 inhibition may facilitate healing of chronic foot ulcers in patients with type 2 diabetes
Margolles_2012_J.Bacteriol_194_4465Genome sequence of the Antarctic psychrophile bacterium Planococcus antarcticus DSM 14505
Marrs_2012_Pest.Manag.Sci_68_1332Toxicology of insecticides to mammals
Marshall_2012_Appl.Environ.Microbiol_78_8555A Single-cell genome for Thiovulum sp
Marshall_2012_J.Cell.Biol_197_1009Sarcospan-dependent Akt activation is required for utrophin expression and muscle regeneration
Martin_2012_J.Bacteriol_194_4466Complete genome sequence of Streptococcus salivarius PS4, a strain isolated from human milk
Martin_2012_J.Neurochem_120_440alpha-Synuclein oligomers oppose long-term potentiation and impair memory through a calcineurin-dependent mechanism: relevance to human synucleopathic diseases
Martin_2012_Nat.Methods_9_84Global profiling of dynamic protein palmitoylation
Martin_2012_Trends.Parasitol_28_289Levamisole receptors: a second awakening
Martinelli_2012_Exp.Diabetes.Res_2012_231502Low levels of serum paraoxonase activities are characteristic of metabolic syndrome and may influence the metabolic-syndrome-related risk of coronary artery disease
Martinez_2012_Appl.Environ.Microbiol_78_6017Identification and biochemical evidence of a medium-chain-length polyhydroxyalkanoate depolymerase in the Bdellovibrio bacteriovorus predatory hydrolytic arsenal
Martinez_2012_J.Vet.Diagn.Invest_24_612Vascular mineralization in the brain of horses
Martinez_2012_MBio_3_e00259Comparative genome analysis of Trichophyton rubrum and related dermatophytes reveals candidate genes involved in infection
Martini_2012_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_68_175Crystallization and preliminary crystallographic analysis of LipC12, a true lipase isolated through a metagenomics approach
Martinowich_2012_Behav.Brain.Funct_8_15Acetylcholinesterase inhibition ameliorates deficits in motivational drive
Martins_2012_Life.Sci_90_35117-beta estradiol in the acetylcholinesterase activity and lipid peroxidation in the brain and blood of ovariectomized adult and middle-aged rats
Martucciello_2012_Ital.J.Pediatr_38_9Multiple endocrine neoplasias type 2B and RET proto-oncogene
Marty_2012_Regul.Toxicol.Pharmacol_63_209Cholinesterase inhibition and toxicokinetics in immature and adult rats after acute or repeated exposures to chlorpyrifos or chlorpyrifos-oxon
Martyn_2012_Proc.Natl.Acad.Sci.U.S.A_109_17651Elimination of the vesicular acetylcholine transporter in the forebrain causes hyperactivity and deficits in spatial memory and long-term potentiation
Maruyama_2012_Int.J.Mol.Sci_13_10553Direct observation of protein microcrystals in crystallization buffer by atmospheric scanning electron microscopy
Masai_2012_J.Bacteriol_194_534Complete genome sequence of Sphingobium sp. strain SYK-6, a degrader of lignin-derived biaryls and monoaryls
Masaki_2012_Appl.Microbiol.Biotechnol_93_1627Construction of a new recombinant protein expression system in the basidiomycetous yeast Cryptococcus sp. strain S-2 and enhancement of the production of a cutinase-like enzyme
Mase_2012_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_68_652Crystallization and preliminary X-ray analysis of the haloalkane dehalogenase DatA from Agrobacterium tumefaciens C58
Maselli_2012_Hum.Genet_131_1123LG2 agrin mutation causing severe congenital myasthenic syndrome mimics functional characteristics of non-neural (z-) agrin
Masha'our_2012_Front.Mol.Neurosci_5_69Acetylcholinesterase (AChE) is an important link in the apoptotic pathway induced by hyperglycemia in Y79 retinoblastoma cell line
Masson_2012_Biochemistry.(Mosc)_77_1147Time-dependent kinetic complexities in cholinesterase-catalyzed reactions
Mata_2012_Bioorg.Med.Chem_20_886A carbamate-based approach to primaquine prodrugs: antimalarial activity, chemical stability and enzymatic activation
Mateos-Diaz_2012_Methods.Mol.Biol_861_89High-throughput screening method for lipases/esterases
Mathe-Allainmat_2012_Insect.Biochem.Mol.Biol_42_417A fluorinated quinuclidine benzamide named LMA 10203 acts as an agonist of insect nicotinic acetylcholine receptors
Matheeussen_2012_Clin.Chim.Acta_413_456Method comparison of dipeptidyl peptidase IV activity assays and their application in biological samples containing reversible inhibitors
Mathew_2012_Bioorg.Med.Chem.Lett_22_6929Extracellular and intracellular esterase processing of SCFA-hexosamine analogs: Implications for metabolic glycoengineering and drug delivery
Matilla_2012_J.Biol.Chem_287_39125Bacterial biosynthetic gene clusters encoding the anti-cancer haterumalide class of molecules: biogenesis of the broad spectrum antifungal and anti-oomycete compound, oocydin A
Matos_2012_J.Biomol.Struct.Dyn_30_546First principles calculations of thermodynamics and kinetic parameters and molecular dynamics simulations of acetylcholinesterase reactivators: can mouse data provide new insights into humans?
Matozzo_2012_Mar.Environ.Res_74_40A multi-biomarker approach to assess effects of Triclosan in the clam Ruditapes philippinarum
Matsubara_2012_Cell.Metab_16_634Metabolomics identifies an inflammatory cascade involved in dioxin- and diet-induced steatohepatitis
Matsuda_2012_ChemBioChem_13_1738Terretonin biosynthesis requires methylation as essential step for cyclization
Matsueda_2012_Gut_61_821A placebo-controlled trial of acotiamide for meal-related symptoms of functional dyspepsia
Matsumoto_2012_PLoS.One_7_e42841Localization of acetylcholine-related molecules in the retina: implication of the communication from photoreceptor to retinal pigment epithelium
Matsutani_2012_Microbiology.(Mosc.)_158_229Genome-wide phylogenetic analysis of differences in thermotolerance among closely related Acetobacter pasteurianus strains
Matuszak_2012_Eur.J.Pharm.Sci_45_263Dual inhibition of MAGL and type II topoisomerase by N-phenylmaleimides as a potential strategy to reduce neuroblastoma cell growth
Maury_2012_Bioessays_34_61Human pluripotent stem cells for disease modelling and drug screening
Mavromatis_2012_Stand.Genomic.Sci_6_210Permanent draft genome sequence of the gliding predator Saprospira grandis strain Sa g1 (= HR1)
Mayer-Pinto_2012_PLoS.One_7_e47871How much is too little to detect impacts? A case study of a nuclear power plant
Mayer_2012_Anal.Chem_84_1047831P-edited diffusion-ordered 1H NMR spectroscopy for the spectral isolation and identification of organophosphorus compounds related to chemical weapons agents and their degradation products
Mayer_2012_Nature_491_711A physical, genetic and functional sequence assembly of the barley genome
Mayford_2012_Cold.Spring.Harb.Perspect.Biol_4_Synapses and memory storage
Mazzon_2012_Blood_119_5502Agrin is required for survival and function of monocytic cells
McAllister_2012_J.Vector.Ecol_37_325Pyrethroid resistance in Aedes aegypti and Aedes albopictus from Port-au-Prince, Haiti
McCarron_2012_J.Agric.Food.Chem_60_1437Identification of pinnatoxins and discovery of their fatty acid ester metabolites in mussels ( Mytilus edulis ) from eastern Canada
McConnell_2012_Neurotoxicol_33_1048Evaluation of multi-well microelectrode arrays for neurotoxicity screening using a chemical training set
McCormick_2012_Appl.Environ.Microbiol_78_8694Glucosylation and other biotransformations of T-2 toxin by yeasts of the trichomonascus clade
McDermott_2012_Ann.Pharmacother_46_599Cholinesterase inhibitor adjunctive therapy for cognitive impairment and depressive symptoms in older adults with depression
McDowell_2012_J.Bacteriol_194_3260Draft genome sequence of an antibiotic-resistant Propionibacterium acnes strain, PRP-38, from the novel type IC cluster
McGarvey_2012_Appl.Environ.Microbiol_78_1708Wide variation in antibiotic resistance proteins identified by functional metagenomic screening of a soil DNA library
McGowin_2012_J.Bacteriol_194_6010Draft genome sequences of four axenic Mycoplasma genitalium strains isolated from Denmark, Japan, and Australia
McKenzie_2012_J.Econ.Entomol_105_753Distribution of Bemisia tabaci (Hemiptera: Aleyrodidae) biotypes in North America after the Q invasion
McMullen_2012_J.Bacteriol_194_3552Genome sequence of Listeria monocytogenes 07PF0776, a cardiotropic serovar 4b strain
Medrano_2012_J.Bacteriol_194_3019Genome sequence of Pantoea sp. strain Sc 1, an opportunistic cotton pathogen
Meek_2012_Toxicol.Sci_126_525Synthesis and in vitro and in vivo inhibition potencies of highly relevant nerve agent surrogates
Mehla_2012_Neurochem.Int_61_1052Amelioration of intracerebroventricular streptozotocin induced cognitive impairment by Evolvulus alsinoides in rats: In vitro and in vivo evidence
Mehta_2012_Front.Biosci.(Elite.Ed)_4_169The nicotinic acetylcholine receptor: smoking and Alzheimer's disease revisited
Mehta_2012_Int.J.Alzheimers.Dis_2012_728983New acetylcholinesterase inhibitors for Alzheimer's disease
Mei_2012_Appl.Microbiol.Biotechnol_93_1965Exceptional thermal stability and organic solvent tolerance of an esterase expressed from a thermophilic host
Meier-Davis_2012_Int.J.Toxicol_31_337Dried blood spot analysis of donepezil in support of a GLP 3-month dose-range finding study in rats
Meincke_2012_Stand.Genomic.Sci_6_74Complete genome sequence of Polynucleobacter necessarius subsp. asymbioticus type strain (QLW-P1DMWA-1(T))
Meinen_2012_PLoS.One_7_e44148Fatigue and muscle atrophy in a mouse model of myasthenia gravis is paralleled by loss of sarcolemmal nNOS
Melancon_2012_Bioorg.Med.Chem.Lett_22_1044Development of a more highly selective M(1) antagonist from the continued optimization of the MLPCN Probe ML012
Melancon_2012_J.Med.Chem_55_1445Allosteric modulation of seven transmembrane spanning receptors: theory, practice, and opportunities for central nervous system drug discovery
Melo_2012_J.Neurochem_120_998Tacrine and its analogues impair mitochondrial function and bioenergetics: a lipidomic analysis in rat brain
Mena_2012_Rev.Biol.Trop_60_361Acute toxicity and cholinesterase inhibition of the nematicide ethoprophos in larvae of gar Atractosteus tropicus (Semionotiformes: Lepisosteidae)
Mendes_2012_Int.J.Biol.Macromol_50_503Evaluation of immobilized lipases on poly-hydroxybutyrate beads to catalyze biodiesel synthesis
Menendez-Helman_2012_Bull.Environ.Contam.Toxicol_88_6Glyphosate as an acetylcholinesterase inhibitor in Cnesterodon decemmaculatus
Meng_2012_Molecules_17_11303Benzopyranones from the endophytic fungus Hyalodendriella sp. Ponipodef12 and their bioactivities
Mensah_2012_Water.Sci.Technol_66_402Acetylcholinesterase activity in the freshwater shrimp Caridina nilotica as a biomarker of Roundup((R)) herbicide pollution of freshwater systems in South Africa
Mercey_2012_Acc.Chem.Res_45_756Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents
Mercey_2012_J.Med.Chem_55_10791Phenyltetrahydroisoquinoline-pyridinaldoxime conjugates as efficient uncharged reactivators for the dephosphylation of inhibited human acetylcholinesterase
Merrill_2012_Neurosci_218_89Identification of mRNA for endocannabinoid biosynthetic enzymes within hippocampal pyramidal cells and CA1 stratum radiatum interneuron subtypes using quantitative real-time polymerase chain reaction
Meshulam_2012_Front.Pharmacol_3_157The role of the neuro-astro-vascular unit in the etiology of ataxia telangiectasia
Mestre_2012_Fungal.Biol_116_825Identification of effector genes from the phytopathogenic Oomycete Plasmopara viticola through the analysis of gene expression in germinated zoospores
Metherate_2012_Front.Behav.Neurosci_6_44Nicotinic filtering of sensory processing in auditory cortex
Michael_2012_J.Antimicrob.Chemother_67_91ICEPmu1, an integrative conjugative element (ICE) of Pasteurella multocida: structure and transfer
Michel_2012_Handb.Exp.Pharmacol_208_49Polymorphisms in human muscarinic receptor subtype genes
Midha_2012_J.Bacteriol_194_3031Genome sequence of Xanthomonas citri pv. mangiferaeindicae strain LMG 941
Mielke_2012_Alzheimers.Dement_8_180Effects of Food and Drug Administration-approved medications for Alzheimer's disease on clinical progression
Mikata_2012_Top.Curr.Chem_314_113Biotransformation and enzymatic reactions of synthetic pyrethroids in mammals
Mikhailova_2012_Biochemistry.(Mosc)_77_300Oligopeptidase B from Serratia proteamaculans. III. Inhibition analysis. Specific interactions with metalloproteinase inhibitors
Mikkelsen_2012_Endocr.Regul_46_13Differential sensitivity to nicotine among hypothalamic magnocellular neurons
Mikkilineni_2012_Parkinsons.Dis_2012_142372The anticholinesterase phenserine and its enantiomer posiphen as 5'untranslated-region-directed translation blockers of the Parkinson's alpha synuclein expression
Milan_2012_Aquat.Toxicol_126C_17Gene transcription and biomarker responses in the clam Ruditapes philippinarum after exposure to ibuprofen
Miller-Roll_2012_Harefuah_151_402[Apnea after general anesthesia for revision of uterus in parturient with K-variant of the butyrylcholinesterase enzyme (BChE)]
Millson_2012_Am.J.Med.Genet.A_158A_159Chromosomal loss of 3q26.3-3q26.32, involving a partial neuroligin 1 deletion, identified by genomic microarray in a child with microcephaly, seizure disorder, and severe intellectual disability
Min_2012_Anal.Bioanal.Chem_404_2397On-line immobilized acetylcholinesterase microreactor for screening of inhibitors from natural extracts by capillary electrophoresis
Min_2012_Neurosci.Lett_510_29Donepezil attenuates hippocampal neuronal damage and cognitive deficits after global cerebral ischemia in gerbils
Minarini_2012_Neuropharmacol_62_997Cystamine-tacrine dimer: a new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment
Mishra_2012_Biosens.Bioelectron_32_56A novel automated flow-based biosensor for the determination of organophosphate pesticides in milk
Misiak_2012_Med.Hypotheses_79_56Translating whole-body cryotherapy into geriatric psychiatry--a proposed strategy for the prevention of Alzheimer's disease
Misik_2012_Clin.Toxicol.(Phila)_50_807In vivo decontamination of the nerve agent VX using the domestic swine model
Misiti_2012_Cell.Biochem.Funct_30_474beta-amyloid decreases detectable endothelial nitric oxide synthase in human erythrocytes: a role for membrane acetylcholinesterase
Mitchelson_2012_Handb.Exp.Pharmacol_208_263Muscarinic receptor agonists and antagonists: effects on ocular function
Mitchelson_2012_Pharmacol.Ther_135_216The pharmacology of McN-A-343
Mitra_2012_J.Food.Sci_77_C39Studies of reaction variables for lipase-catalyzed production of alpha-linolenic acid enriched structured lipid and oxidative stability with antioxidants
Miwa_2012_Physiology.(Bethesda)_27_187Optimizing cholinergic tone through lynx modulators of nicotinic receptors: implications for plasticity and nicotine addiction
Miyazaki_2012_Clin.Sci.(Lond)_123_241Acetylcholinesterase inhibitors attenuate angiogenesis
Miyoshi-Akiyama_2012_J.Bacteriol_194_2770Complete annotated genome sequence of Mycobacterium tuberculosis Erdman
Miyoshi-Akiyama_2012_J.Bacteriol_194_5692Complete genome sequence of Helicobacter cinaedi type strain ATCC BAA-847
Mohamed_2012_Arch.Pharm.Res_35_1369Design and synthesis of novel 1,4-benzodiazepine derivatives and their biological evaluation as cholinesterase inhibitors
Mohamed_2012_Bioorg.Med.Chem.Lett_22_4707Development and evaluation of multifunctional agents for potential treatment of Alzheimer's disease: application to a pyrimidine-2,4-diamine template
Mohamed_2012_Steroids_77_1469One-pot three-component synthesis of novel heterocyclic steroids as a central antioxidant and anti-inflammatory agents
Mohr_2012_Neuropharmacol_67C_37Mice heterozygous for AChE are more sensitive to AChE inhibitors but do not respond to BCHE inhibition
Mollataghi_2012_Fitoterapia_83_298Anti-acetylcholinesterase, anti-alpha-glucosidase, anti-leishmanial and anti-fungal activities of chemical constituents of Beilschmiedia species
Monnet_2012_J.Bacteriol_194_738Genome sequence of Corynebacterium casei UCMA 3821, isolated from a smear-ripened cheese
Montella_2012_Mem.Inst.Oswaldo.Cruz_107_437The classification of esterases: an important gene family involved in insecticide resistance--a review
Montolio_2012_J.Med.Chem_55_9838Identification of Small Molecule Inhibitors of Amyloid beta-Induced Neuronal Apoptosis Acting through the Imidazoline I(2) Receptor
Morak_2012_Mol.Cell.Proteomics_11_1777Adipose Triglyceride Lipase (ATGL) and Hormone-Sensitive Lipase (HSL) Deficiencies Affect Expression of Lipolytic Activities in Mouse Adipose Tissues
Moravcova_2012_Mil.Med.Sci.Lett_81_129Using the pig's brain acetylcholinesterase immobilized on a textile fiber to test the antidotes of nerve agent poisonings - part I
Moreau_2012_Mol.Plant.Microbe.Interact_25_421EDS1 contributes to nonhost resistance of Arabidopsis thaliana against Erwinia amylovora
Moreira_2012_J.Alzheimers.Dis_32_495Age-Related Cognitive Decline in Hypercholesterolemic LDL Receptor Knockout Mice (LDLr-/-): Evidence of Antioxidant Imbalance and Increased Acetylcholinesterase Activity in the Prefrontal Cortex
Morera_2012_Bioorg.Med.Chem_20_6260Development and characterization of endocannabinoid hydrolases FAAH and MAGL inhibitors bearing a benzotriazol-1-yl carboxamide scaffold
Mori_2012_Am.J.Pathol_180_798Antibodies against muscle-specific kinase impair both presynaptic and postsynaptic functions in a murine model of myasthenia gravis
Mori_2012_Ann.Neurol_72_41Donepezil for dementia with Lewy bodies: a randomized, placebo-controlled trial
Mori_2012_J.Neuroimmunol_245_753,4-Diaminopyridine improves neuromuscular transmission in a MuSK antibody-induced mouse model of myasthenia gravis
Morin_2012_Proc.Natl.Acad.Sci.U.S.A_109_17501Genome sequence of the button mushroom Agaricus bisporus reveals mechanisms governing adaptation to a humic-rich ecological niche
Morino_2012_Diabetes_61_877Regulation of mitochondrial biogenesis by lipoprotein lipase in muscle of insulin-resistant offspring of parents with type 2 diabetes
Mosca_2012_Nature_484_237Trans-synaptic Teneurin signalling in neuromuscular synapse organization and target choice
Moser_2012_Bioorg.Med.Chem.Lett_22_6762Evaluation of structure-derived pharmacophore of soluble epoxide hydrolase inhibitors by virtual screening
Moser_2012_Toxicol.Sci_129_126Impact of chemical proportions on the acute neurotoxicity of a mixture of seven carbamates in preweanling and adult rats
Moshiri_2012_Daru_20_81Advances in toxicology and medical treatment of chemical warfare nerve agents
Mossello_2012_Ther.Adv.Chronic.Dis_3_183Management of patients with Alzheimer's disease: pharmacological treatment and quality of life
Mostafalou_2012_Toxicol.Ind.Health_28_840Biochemical evidence on the potential role of organophosphates in hepatic glucose metabolism toward insulin resistance through inflammatory signaling and free radical pathways
Mounier-Vehier_2012_Presse.Med_41_1090[Orthostatic hypotension: a potential independent cardiovascular risk factor]
Mourot_2012_Nat.Methods_9_396Rapid optical control of nociception with an ion-channel photoswitch
Mourou_2012_Malar.J_11_40Malaria transmission in Libreville: results of a one year survey
Mouslim_2012_J.Neurosci_32_5177A role for the calmodulin kinase II-related anchoring protein (alphakap) in maintaining the stability of nicotinic acetylcholine receptors
Mozer_2012_Mol.Cell.Neurosci_51_89Drosophila neuroligin 1 regulates synaptic growth and function in response to activity and phosphoinositide-3-kinase
Msika_2012_Biochim.Biophys.Acta_1821_1022NGF blocks polyunsaturated fatty acids biosynthesis in n-3 fatty acid-supplemented PC12 cells
Mu_2012_Talanta_88_711Evaluation of a new substrate for measurement of serum PON arylesterase activity
Mugford_2012_Methods.Enzymol_516_279Serine carboxypeptidase-like acyltransferases from plants
Mukaetova-Ladinska_2012_J.Alzheimers.Dis_32_431Increase in Platelet Immunoglobulin in Alzheimer's Disease is Normalised Following Cholinesterase Inhibitor Treatment: Preliminary Results
Mukhamadieva_2012_Pharm.Chem.J_46_461Synthesis and biological activity of O-carbamoylated 1,1,1,3,3,3-hexafluoroisopropanols as new specific inhibitors of carboxylesterase
Mulaudzi_2012_J.Ethnopharmacol_143_185Pharmacological properties and protein binding capacity of phenolic extracts of some Venda medicinal plants used against cough and fever
Munasinghe_2012_Neurodegener.Dis_9_159Evaluation of neurodegeneration in a mouse model of infantile batten disease by magnetic resonance imaging and magnetic resonance spectroscopy
Munday_2012_Toxicon_60_995Acute toxicity of pinnatoxins E, F and G to mice
Munoz-Barrios_2012_Dis.Markers_33_313Association of the HindIII and S447X polymorphisms in LPL gene with hypertension and type 2 diabetes in Mexican families
Munoz-Torrero_2012_Neurodegener.Dis_10_96Expanding the multipotent profile of huprine-tacrine heterodimers as disease-modifying anti-Alzheimer agents
Munro_2012_Br.J.Pharmacol_167_421The alpha7 nicotinic ACh receptor agonist compound B and positive allosteric modulator PNU-120596 both alleviate inflammatory hyperalgesia and cytokine release in the rat
Munshaw_2012_Hepatology_56_544Laser captured hepatocytes show association of butyrylcholinesterase gene loss and fibrosis progression in hepatitis C-infected drug users
Murase_2012_Clin.Chim.Acta_414_185Hepatic lipase activity is decreased in Japanese patients with type III hyperlipoproteinemia
Murray_2012_Mol.Pharmacol_81_175alpha7beta2 nicotinic acetylcholine receptors assemble, function, and are activated primarily via their alpha7-alpha7 interfaces
Murrell_2012_J.Am.Acad.Dermatol_66_479Definitions and outcome measures for bullous pemphigoid: recommendations by an international panel of experts
Muthukrishnan_2012_J.Phys.Org.Chem_25_1247Mechanistic Insights into the Hydrolysis of Organophosphorus Compounds by Paraoxonase-1: Exploring the Limits of Substrate Tolerance in a Promiscuous Enzyme
Mwanza_2012_Neurotoxicol_33_332Cholinesterase inhibition and depression of the photic after discharge of flash evoked potentials following acute or repeated exposures to a mixture of carbaryl and propoxur
Myers_2012_Neurotoxicol.Teratol_34_323Characterization of human serum butyrylcholinesterase in rhesus monkeys: behavioral and physiological effects
Myohanen_2012_Br.J.Pharmacol_166_1097A prolyl oligopeptidase inhibitor, KYP-2047, reduces alpha-synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease
Nachmany_2012_Dis.Markers_32_211Two potential biomarkers identified in mesenchymal stem cells and leukocytes of patients with sporadic amyotrophic lateral sclerosis
Nagahama_2012_Neurogastroenterol.Motil_24_566Acotiamide, a new orally active acetylcholinesterase inhibitor, stimulates gastrointestinal motor activity in conscious dogs
Nagaki_2012_Plant.Cell.Rep_31_771Isolation of centromeric-tandem repetitive DNA sequences by chromatin affinity purification using a HaloTag7-fused centromere-specific histone H3 in tobacco
Nagarajan_2012_Appl.Biochem.Biotechnol_168_1163New tools for exploring old friends-microbial lipases
Nagashima_2012_J.Bacteriol_194_3541Complete genome sequence of phototrophic betaproteobacterium Rubrivivax gelatinosus IL144
Nagy_2012_J.Phys.Chem.B_116_5425On the interaction of aliphatic amines and ammonium ions with carboxylic acids in solution and in receptor pockets
Nagy_2012_Neurosci_218_1Overexpression of the vesicular acetylcholine transporter increased acetylcholine release in the hippocampus
Naidoo_2012_Neurotherapeutics_9_801Equipotent inhibition of fatty acid amide hydrolase and monoacylglycerol lipase - dual targets of the endocannabinoid system to protect against seizure pathology
Nair_2012_Nat.Prod.Commun_7_959Acetylcholinesterase inhibition within the lycorine series of Amaryllidaceae alkaloids
Nakayama_2012_Chemistry_18_8392Substrate specificity of fluoroacetate dehalogenase: an insight from crystallographic analysis, fluorescence spectroscopy, and theoretical computations
Nakazawa_2012_Methods.Mol.Biol_861_179Streptomyces phospholipase D cloning and production
Nam_2012_Ecotoxicology_21_1094Elevated mercury exposure and neurochemical alterations in little brown bats (Myotis lucifugus) from a site with historical mercury contamination
Namountougou_2012_PLoS.One_7_e48412Multiple Insecticide Resistance in Anopheles gambiae s.l. Populations from Burkina Faso, West Africa
Namovic_2012_Curr.Protoc.Pharmacol_Chapter 9_Unit 9 15High throughput functional assays for P2X receptors
Nanthakumar_2012_Pestic.Biochem.Physiol_102_146Decrease of rice plant resistance and induction of hormesis and carboxylesterase titre in brown planthopper, Nilaparvata lugens (Stal) by xenobiotics
Nareoja_2012_Acta.Physiol.(Oxf)_204_186Selective targeting of G-protein-coupled receptor subtypes with venom peptides
Nareoja_2012_Biochem.Biophys.Res.Commun_417_93Glycosylphosphatidylinositol (GPI)-anchoring of mamba toxins enables cell-restricted receptor silencing
Nareoja_2012_Biotechnol.Appl.Biochem_59_314Enhanced early expression of membrane receptors with the Rous sarcoma virus promoter in baculovirus-infected insect cells
Nareoja_2012_Eur.J.Pharmacol_683_63Characterization of alpha(2B)-adrenoceptor ligand binding in the presence of muscarinic toxin alpha and delineation of structural features of receptor binding selectivity
Narimatsu_2012_Am.J.Emerg.Med_30_901Pralidoxime inhibits paraoxon-induced depression of rocuronium-neuromuscular block in a time-dependent fashion
Nasab_2012_J.Pak.Med.Assoc_62_677Efficacy of rivastigmine in comparison to ginkgo for treating Alzheimer's dementia
Nasir_2012_Phytomedicine_19_311Inhibitory effect of asiatic acid on acetylcholinesterase, excitatory post synaptic potential and locomotor activity
Nasuno_2012_Appl.Environ.Microbiol_78_8067Phylogenetically novel LuxI/LuxR-type quorum sensing systems isolated using a metagenomic approach
Nathan_2012_Exp.Neurol_237_1Long-term effects of estradiol replacement in the olfactory system
Navab_2012_J.Lipid.Res_53_437D-4F-mediated reduction in metabolites of arachidonic and linoleic acids in the small intestine is associated with decreased inflammation in low-density lipoprotein receptor-null mice
Navia-Paldanius_2012_J.Lipid.Res_53_2413Biochemical and pharmacological characterization of human alpha/beta-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12)
Nayak_2012_J.Gen.Physiol_139_349The intrinsic energy of the gating isomerization of a neuromuscular acetylcholine receptor channel
Nazarov_2012_Life.Sci_91_1053The influence of cholinergic agents on histamine release from HMC-1 human mast cell line stimulated with IgG, C-reactive protein and compound 48/80
Nazarova_2012_Bull.Exp.Biol.Med_153_674Changes in activity of proline-specific peptidases in rat model for dementia of Alzheimer's type
Nazir_2012_J.Bacteriol_194_4480Draft genome sequence of the soil bacterium Burkholderia terrae strain BS001, which interacts with fungal surface structures
Ndiaye_2012_Environ.Sci.Pollut.Res.Int_19_4133Multiparametric approach for assessing environmental quality variations in West African aquatic ecosystems using the black-chinned tilapia (Sarotherodon melanotheron) as a sentinel species
Neckar_2012_Clin.Sci.(Lond)_122_513Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension
Nelson_2012_Annu.Rev.Plant.Biol_63_107Regulation of seed germination and seedling growth by chemical signals from burning vegetation
Neupane_2012_Stand.Genomic.Sci_6_165Complete genome sequence of Serratia plymuthica strain AS12
Neupane_2012_Stand.Genomic.Sci_6_54Complete genome sequence of the rapeseed plant-growth promoting Serratia plymuthica strain AS9
Neupane_2012_Stand.Genomic.Sci_7_22Complete genome sequence of the plant-associated Serratia plymuthica strain AS13
Newington_2012_J.Biol.Chem_287_37245Overexpression of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase A in nerve cells confers resistance to amyloid beta and other toxins by decreasing mitochondrial respiration and reactive oxygen species production
Nguyen_2012_Nutrients_4_1058Impaired insulin/IGF signaling in experimental alcohol-related myopathy
Nickel_2012_Bioorg.Med.Chem_20_601A para-nitrophenol phosphonate probe labels distinct serine hydrolases of Arabidopsis
Nicolaou_2012_Electrophoresis_33_644Development of a capillary electrophoresis-mass spectrometry method for the determination of rivastigmine in human plasma--optimization of the limits of detection and quantitation
Nie_2012_PLoS.One_7_e44780beta2-Agonists inhibit TNF-alpha-induced ICAM-1 expression in human airway parasympathetic neurons
Niessen_2012_Drug.Test.Anal_4_292Competition radioligand binding assays for the investigation of bispyridinium compound affinities to the human muscarinic acetylcholine receptor subtype 5 (hM(5) )
Niewerth_2012_BMC.Genomics_13_534Complete genome sequence and metabolic potential of the quinaldine-degrading bacterium Arthrobacter sp. Rue61a
Nijkamp_2012_Microb.Cell.Fact_11_36De novo sequencing, assembly and analysis of the genome of the laboratory strain Saccharomyces cerevisiae CEN.PK113-7D, a model for modern industrial biotechnology
Nilin_2012_Bull.Environ.Contam.Toxicol_88_707Bivalve esterases as biomarker: identification and characterization in European cockles (Cerastoderma edule)
Niphakis_2012_ACS.Chem.Neurosci_3_418O-hydroxyacetamide carbamates as a highly potent and selective class of endocannabinoid hydrolase inhibitors
Nirogi_2012_J.Pharmacol.Toxicol.Methods_65_136Rat thalamic alpha(4)beta(2) neuronal nicotinic acetylcholine receptor occupancy assay using LC-MS/MS
Nishimune_2012_Ann.N.Y.Acad.Sci_1274_24Active zones of mammalian neuromuscular junctions: formation, density, and aging
Nishimune_2012_Mol.Neurobiol_45_1Molecular mechanism of active zone organization at vertebrate neuromuscular junctions
Nishimune_2012_PLoS.One_7_e38029Active zone protein Bassoon co-localizes with presynaptic calcium channel, modifies channel function, and recovers from aging related loss by exercise
Niu_2012_Mol.Neurodegener_7Suppl1_S11Acetylcholinesterase blocks cleavage of APP by gamma-secretase in 293 cells and mouse brain
Nomura_2012_Plant.Physiol_159_565A novel lactone-forming carboxylesterase: molecular identification of a tuliposide A-converting enzyme in tulip
Noori_2012_Synapse_66_893The impact of acetylcholinesterase inhibitors on the extracellular acetylcholine concentrations in the adult rat brain: a meta-analysis
Nordman_2012_J.Cell.Sci_125_5502An interaction between alpha7 nicotinic receptors and a G-protein pathway complex regulates neurite growth in neural cells
Normand_2012_J.Bacteriol_194_4773Genome sequence of radiation-resistant Modestobacter marinus strain BC501, a representative actinobacterium that thrives on calcareous stone surfaces
Novak_2012_Nat.Prod.Commun_7_859Corylucinine, a new alkaloid from Corydalis cava (Fumariaceae), and its cholinesterase activity
Novototskaya-Vlasova_2012_FEMS.Microbiol.Ecol_82_367Cloning, purification, and characterization of a cold-adapted esterase produced by Psychrobacter cryohalolentis K5T from Siberian cryopeg
Ntalli_2012_J.Agric.Food.Chem_60_9929Botanical nematicides: a review
Nunes-Tavares_2012_J.Biol.Chem_287_19377Inhibition of choline acetyltransferase as a mechanism for cholinergic dysfunction induced by amyloid-beta peptide oligomers
Nykyri_2012_PLoS.Pathog_8_E1003013Revised phylogeny and novel horizontally acquired virulence determinants of the model soft rot phytopathogen Pectobacterium wasabiae SCC3193
Nyren_2012_BMC.Physiol_12_14Localization of lipoprotein lipase and GPIHBP1 in mouse pancreas: effects of diet and leptin deficiency
O'Brien_2012_BMC.Microbiol_12_141Extensive remodeling of the Pseudomonas syringae pv. avellanae type III secretome associated with two independent host shifts onto hazelnut
O'Carroll_2012_Neurologist_18_51Is donepezil effective for multiple sclerosis-related cognitive dysfunction? A critically appraised topic
O'Connell_2012_Bioorg.Med.Chem.Lett_22_1397Design and synthesis of boronic acid inhibitors of endothelial lipase
O'Connell_2012_Nat.Genet_44_1060Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses
Oboh_2012_Exp.Toxicol.Pathol_64_315Inhibition of acetylcholinesterase activities and some pro-oxidant induced lipid peroxidation in rat brain by two varieties of ginger (Zingiber officinale)
Obrowsky_2012_Biochim.Biophys.Acta_1821_1406Cholesteryl ester accumulation and accelerated cholesterol absorption in intestine-specific hormone sensitive lipase-null mice
Ocampo_2012_BMC.Evol.Biol_12_231The evolution of vertebrate somatostatin receptors and their gene regions involves extensive chromosomal rearrangements
Oenema_2012_Am.J.Physiol.Lung.Cell.Mol.Physiol_303_L589Muscarinic receptor stimulation augments TGF-beta1-induced contractile protein expression by airway smooth muscle cells
Ofek_2012_J.Cell.Mol.Med_16_2736Fluoxetine induces vasodilatation of cerebral arterioles by co-modulating NO/muscarinic signalling
Ohira_2012_Metabolism_61_1452Atorvastatin and pitavastatin enhance lipoprotein lipase production in L6 skeletal muscle cells through activation of adenosine monophosphate-activated protein kinase
Ohlendorf_2012_J.Nat.Prod_75_1400Geranylphenazinediol, an acetylcholinesterase inhibitor produced by a Streptomyces species
Ohm_2012_PLoS.Pathog_8_E1003037Diverse lifestyles and strategies of plant pathogenesis encoded in the genomes of eighteen Dothideomycetes fungi
Ohno_2012_Rinsho.Shinkeigaku_52_1159Congenital myasthenic syndromes
Ohno_2012_Rinsho.Shinkeigaku_52_1306Anti-MuSK antibodies in myasthenia gravis block binding of collagen Q to MuSK
Ohtsubo_2012_J.Bacteriol_194_6970Complete genome sequence of Acidovorax sp. strain KKS102, a polychlorinated-biphenyl degrader
Ohya_2012_Nucl.Med.Commun_33_1019A method to predict the ratio of the tracer conversion rate to the tracer back-diffusion rate of an irreversible-type radiotracer in humans by preclinical evaluations
Okamura_2012_Toxicol.Lett_210_220New analytical method for sensitive quantification of urinary 3-methyl-4-nitrophenol to assess fenitrothion exposure in general population and occupational sprayers
Okello_2012_Food.Funct_3_651Inhibition of acetylcholinesterase by green and white tea and their simulated intestinal metabolites
Okonogi_2012_Drug.Discov.Ther_6_249Enhancement of anti-cholinesterase activity of Zingiber cassumunar essential oil using a microemulsion technique
Okrob_2012_Chembiochem_13_797Tailoring a stabilized variant of hydroxynitrile lyase from Arabidopsis thaliana
Okubo_2012_Microbes.Environ_27_306Complete genome sequence of Bradyrhizobium sp. S23321: insights into symbiosis evolution in soil oligotrophs
Okumura_2012_J.Bacteriol_194_3014Complete genome sequence of Melissococcus plutonius DAT561, a strain that shows an unusual growth profile and is representative of an endemic cluster in Japan
Olazaran_2012_Dement.Geriatr.Cogn.Dis.Extra_2_400Alzheimer's disease with vascular component: a distinct clinical entity?
Olde_2012_Ned.Tijdschr.Geneeskd_156_A5554[Role of secondary care too small in Dutch College of General Practitioners' (NHG) practice guideline 'Dementia']
Olianas_2012_Mol.Pharmacol_81_154delta-Opioid receptors stimulate the metabolic sensor AMP-activated protein kinase through coincident signaling with G(q/11)-coupled receptors
Olincy_2012_Handb.Exp.Pharmacol__211Nicotinic mechanisms in the treatment of psychotic disorders: a focus on the alpha7 nicotinic receptor
Oliva_2012_Mar.Pollut.Bull_64_2097Biomarkers responses in muscle of Senegal sole (Solea senegalensis) from a heavy metals and PAHs polluted estuary
Olivas_2012_PLoS.ONE_7_E44326Intestinal tissues induce an SNP mutation in Pseudomonas aeruginosa that enhances its virulence: possible role in anastomotic leak
Oliveira_2012_Aquat.Toxicol_124-125_209Acute effects of deltamethrin on swimming velocity and biomarkers of the common prawn Palaemon serratus
Olofsson_2012_Immunol.Rev_248_188Rethinking inflammation: neural circuits in the regulation of immunity
Olofsson_2012_Mol.Med_18_539alpha7 nicotinic acetylcholine receptor (alpha7nAChR) expression in bone marrow-derived non-T cells is required for the inflammatory reflex
Olson_2012_New.Phytol_194_1001Insight into trade-off between wood decay and parasitism from the genome of a fungal forest pathogen
Ondachi_2012_J.Med.Chem_55_6512Synthesis and nicotinic acetylcholine receptor in vitro and in vivo pharmacological properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues of 2'-fluoro-3'-(4-nitrophenyl)deschloroepibatidine
Ondracek_2012_Neuro.Endocrinol.Lett_33_155Risk of combined exposure of birds to cyanobacterial biomass containing microcystins, acetylcholinesterase inhibitor and anticoagulant
Ong_2012_J.Bacteriol_194_2115Complete genome sequence of Salmonella enterica subsp. enterica serovar Typhi P-stx-12
Onodera_2012_J.Bacteriol_194_3022Genome sequence of Shigella flexneri serotype 5a strain M90T Sm
Ooi_2012_Arterioscler.Thromb.Vasc.Biol_32_459Apolipoprotein B-100-containing lipoprotein metabolism in subjects with lipoprotein lipase gene mutations
Orejarena_2012_Neuropharmacol_63_235Selective re-expression of beta2 nicotinic acetylcholine receptor subunits in the ventral tegmental area of the mouse restores intravenous nicotine self-administration
Orhan_2012_Curr.Med.Chem_19_2252Current concepts on selected plant secondary metabolites with promising inhibitory effects against enzymes linked to Alzheimer's disease
Orhan_2012_J.Ethnopharmacol_141_220UPLC-TOF-MS analysis of Galium spurium towards its neuroprotective and anticonvulsant activities
Origlia_2012_Invest.Ophthalmol.Vis.Sci_53_1211Visual acuity is reduced in alpha 7 nicotinic receptor knockout mice
Ormeno-Orrillo_2012_BMC.Genomics_13_735Genomic basis of broad host range and environmental adaptability of Rhizobium tropici CIAT 899 and Rhizobium sp. PRF 81 which are used in inoculants for common bean (Phaseolus vulgaris L.)
Ormeno-Orrillo_2012_J.Bacteriol_194_6927Genome sequences of Burkholderia sp. strains CCGE1002 and H160, isolated from legume nodules in Mexico and Brazil
Ortiz_2012_Int.J.Dermatol_51_250Smoking and the skin
Ortiz_2012_Molecules_17_13473Wild Argentinian Amaryllidaceae, a New Renewable Source of the Acetylcholinesterase Inhibitor Galanthamine and Other Alkaloids
Oruc_2012_Bull.Environ.Contam.Toxicol_88_678Oxidative stress responses and recovery patterns in the liver of Oreochromis niloticus exposed to chlorpyrifos-ethyl
Osipov_2012_J.Biol.Chem_287_6725Dimeric alpha-cobratoxin X-ray structure: localization of intermolecular disulfides and possible mode of binding to nicotinic acetylcholine receptors
Osmonov_2012_Am.J.Alzheimers.Dis.Other.Demen_27_311Anticholinesterase-induced symptoms improved by pacemaker implantation in patients with Alzheimer's disease: analysis of 6 cases
Osta_2012_Parasit.Vectors_5_132Insecticide resistance to organophosphates in Culex pipiens complex from Lebanon
Ou_2012_Neuroepidemiology_40_42Does Alzheimer's Disease Protect against Cancers? A Nationwide Population-Based Study
Ovsepian_2012_J.Neurophysiol_108_406Intrinsic voltage dynamics govern the diversity of spontaneous firing profiles in basal forebrain noncholinergic neurons
Owald_2012_Nat.Neurosci_15_1219Cooperation of Syd-1 with Neurexin synchronizes pre- with postsynaptic assembly
Ownby_2012_Ageing.Res_3_e2Relations between cognitive status and medication adherence in patients treated for memory disorders
Ozaki_2012_Psychogeriatrics_12_255Donepezil-induced sleep spindle in a patient with dementia with Lewy bodies: a case report
Ozkay_2012_Pharmacol.Rep_64_834Effect of benzothiazole/piperazine derivatives on intracerebroventricular streptozotocin-induced cognitive deficits
Ozyilmaz_2012_Food.Chem_135_2326Isoamylacetate production by entrapped and covalently bound Candida rugosa and porcine pancreatic lipases
Pachauri_2012_J.Ethnopharmacol_139_34Protective effect of fruits of Morinda citrifolia L. on scopolamine induced memory impairment in mice: a behavioral, biochemical and cerebral blood flow study
Padamsee_2012_Fungal.Genet.Biol_49_217The genome of the xerotolerant mold Wallemia sebi reveals adaptations to osmotic stress and suggests cryptic sexual reproduction
Padilla_2012_Reprod.Toxicol_33_174Zebrafish developmental screening of the ToxCast Phase I chemical library
Padonou_2012_Parasit.Vectors_5_72Impact of three years of large scale Indoor Residual Spraying (IRS) and Insecticide Treated Nets (ITNs) interventions on insecticide resistance in Anopheles gambiae s.l. in Benin
Pahuja_2012_Epilepsy.Res_98_157Root extract of Anacyclus pyrethrum ameliorates seizures, seizure-induced oxidative stress and cognitive impairment in experimental animals
Palais_2012_Ecotoxicology_21_888One-year monitoring of core biomarker and digestive enzyme responses in transplanted zebra mussels (Dreissena polymorpha)
Palanikumar_2012_Ecotoxicol.Environ.Saf_75_187Biochemical response of anthracene and benzo [a] pyrene in milkfish Chanos chanos
Palczynska_2012_Mol.Pharmacol_82_910Activation of alpha7 nicotinic receptors by orthosteric and allosteric agonists: influence on single-channel kinetics and conductance
Palea_2012_Eur.J.Pharmacol_690_202Fenoterol functionally activates the beta(3)-adrenoceptor in human urinary bladder, comparison with rat and mouse: implications for drug discovery
Palomo_2012_Methods.Mol.Biol_861_329Different strategies for hyperactivation of lipase biocatalysts
Pan_2012_J.Agric.Food.Chem_60_9673Efficient display of active Geotrichum sp. lipase on Pichia pastoris cell wall and its application as a whole-cell biocatalyst to enrich EPA and DHA in fish oil
Pan_2012_Neurotoxicol_33_1219Alpha-linolenic acid is a potent neuroprotective agent against soman-induced neuropathology
Pan_2012_Zhonghua.Gan.Zang.Bing.Za.Zhi_20_434[Multivariate analysis of hepatic encephalopathy occurrence in patients with liver failure]
Pandanaboina_2012_Acta.Pol.Pharm_69_833Tramadol safety--cholinergic system of rat brain without nociception
Pandhare_2012_Biochemistry_51_2425Bupropion binds to two sites in the Torpedo nicotinic acetylcholine receptor transmembrane domain: a photoaffinity labeling study with the bupropion analogue [(125)I]-SADU-3-72
Pang_2012_Curr.Drug.Targets_13_471Novel and viable acetylcholinesterase target site for developing effective and environmentally safe insecticides
Pap_2012_J.Inorg.Biochem_108_15Bio-inspired flavonol and quinolone dioxygenation by a non-heme iron catalyst modeling the action of flavonol and 3-hydroxy-4(1H)-quinolone 2,4-dioxygenases
Papaleo_2012_J.Mol.Graph.Model_38C_226Coupled motions during dynamics reveal a tunnel toward the active site regulated by the N-terminal alpha-helix in an acylaminoacyl peptidase
Papaleo_2012_PLoS.One_7_e35686Mechanisms of intramolecular communication in a hyperthermophilic acylaminoacyl peptidase: a molecular dynamics investigation
Papke_2012_Biochem.Pharmacol_84_352The nicotinic acetylcholine receptors of zebrafish and an evaluation of pharmacological tools used for their study
Pariente_2012_Arch.Intern.Med_172_648Antipsychotic use and myocardial infarction in older patients with treated dementia
Pariente_2012_Neurology_78_957Effect of treatment gaps in elderly patients with dementia treated with cholinesterase inhibitors
Parizzi_2012_BMC.Genomics_13_562The genome sequence of Propionibacterium acidipropionici provides insights into its biotechnological and industrial potential
Park_2012_BMC.Genomics_13_545Comparative genomics of the classical Bordetella subspecies: the evolution and exchange of virulence-associated diversity amongst closely related pathogens
Park_2012_Environ.Pollut_167_163Global gene expression in larval zebrafish (Danio rerio) exposed to selective serotonin reuptake inhibitors (fluoxetine and sertraline) reveals unique expression profiles and potential biomarkers of exposure
Park_2012_Evid.Based.Complement.Alternat.Med_2012_601018Chronic Treatment with Squid Phosphatidylserine Activates Glucose Uptake and Ameliorates TMT-Induced Cognitive Deficit in Rats via Activation of Cholinergic Systems
Park_2012_J.Bacteriol_194_4128Draft genome sequence of the sulfur-oxidizing bacterium Candidatus Sulfurovum sediminum AR, which belongs to the Epsilonproteobacteria
Park_2012_J.Bacteriol_194_5445Draft genome sequence of Fusobacterium nucleatum subsp. fusiforme ATCC 51190T
Park_2012_J.Bacteriol_194_6322Draft genome sequence of Fusobacterium nucleatum ChDC F128, isolated from a periodontitis lesion
Park_2012_J.Bacteriol_194_6345Genome sequence of Pectobacterium carotovorum subsp. carotovorum strain PCC21, a pathogen causing soft rot in Chinese cabbage
Park_2012_J.Ethnopharmacol_143_611The memory ameliorating effects of INM-176, an ethanolic extract of Angelica gigas, against scopolamine- or Abeta(1-42)-induced cognitive dysfunction in mice
Park_2012_Pestic.Biochem.Physiol_104_118Neuroprotective properties of phytochemicals against paraquat-induced oxidative stress and neurotoxicity in Drosophila melanogaster
Parker_2012_Appl.Environ.Microbiol_78_1385Differentiation of Xylella fastidiosa strains via multilocus sequence analysis of environmentally mediated genes (MLSA-E)
Parnell_2012_Life.Sci_91_1093Muscarinic cholinergic signaling in cervical cancer cells affects cell motility via ERK1/2 signaling
Parrish_2012_S.Afr.Med.J_102_223Does the nose know? Amitraz poisoning and olfaction
Patel_2012_Arh.Hig.Rada.Toksikol_63_377Monocrotophos poisoning through contaminated millet flour
Patel_2012_J.Clin.Oncol_30_412Evaluation of the role of UGT1A1 genotype testing in colorectal cancer patients administered irinotecan and the occurence of grade 3 and 4 neutropenia
Patel_2012_J.Complement.Integr.Med_9_Article 23Sphaeranthus indicus flower derived constituents exhibits synergistic effect against acetylcholinesterase and possess potential antiamnestic activity
Paterson_2012_Nature_492_423Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres
Patil_2012_Indian.J.Clin.Biochem_27_134Effect of vitamin e supplementation on biochemical parameters in pesticides sprayers of grape gardens of Western maharashtra (India)
Patterson_2012_PLoS.One_7_e43592Characterization and differential gene expression between two phenotypic phase variants in Salmonella enterica serovar Typhimurium
Pauwels_2012_PLoS.One_7_e36999Decoding the folding of Burkholderia glumae lipase: folding intermediates en route to kinetic stability
Pavlidis_2012_Bioresour.Technol_115_164Development of effective nanobiocatalytic systems through the immobilization of hydrolases on functionalized carbon-based nanomaterials
Pavlovsky_2012_Brain.Res_1472_99Stress-induced altered cholinergic-glutamatergic interactions in the mouse hippocampus
Pawar_2012_J.Bacteriol_194_6629Genome sequence of Janibacter hoylei MTCC8307, isolated from the stratospheric air
Payan-Renteria_2012_Arch.Environ.Occup.Health_67_22Effect of chronic pesticide exposure in farm workers of a Mexico community
Paz_2012_Protein.Sci_21_1138Structural and functional characterization of the interaction of the photosensitizing probe methylene blue with Torpedo californica acetylcholinesterase
Pazos_2012_Chem.Commun.(Camb)_48_9534Detection of phosphorylation states by intermolecular sensitization of lanthanide-peptide conjugates
Pecic_2012_Bioorg.Med.Chem.Lett_22_601Design, synthesis and evaluation of non-urea inhibitors of soluble epoxide hydrolase
Peixoto_2012_Neuron_76_396Transsynaptic signaling by activity-dependent cleavage of neuroligin-1
Pejin_2012_Nat.Prod.Res_26_1634Acetylcholinesterase inhibition activity of acetylated depsidones from Lobaria pulmonaria
Peleg_2012_PLoS.ONE_7_E46984The success of acinetobacter species; genetic, metabolic and virulence attributes
Pena_2012_J.Bacteriol_194_1277Draft genome of Pseudomonas stutzeri strain ZoBell (CCUG 16156), a marine isolate and model organism for denitrification studies
Peng_2012_Bioorg.Med.Chem_20_6739Design, synthesis, and bioevaluation of benzamides: novel acetylcholinesterase inhibitors with multi-functions on butylcholinesterase, Abeta aggregation, and beta-secretase
Peng_2012_Methods.Mol.Biol_814_177Astrocyte polarization and wound healing in culture: studying cell adhesion molecules
Pepino_2012_J.Lipid.Res_53_561The fatty acid translocase gene CD36 and lingual lipase influence oral sensitivity to fat in obese subjects
Pereira_2012_Neurotoxicol_33_469Endosulfan exposure inhibits brain AChE activity and impairs swimming performance in adult zebrafish (Danio rerio)
Pereira_2012_Sci.Total.Environ_443C_821Dimethoate affects cholinesterases in Folsomia candida and their locomotion - False negative results of an avoidance behaviour test
Perez-Garcia_2012_Cell.Rep_2_497Increasing MuSK activity delays denervation and improves motor function in ALS mice
Perez-Poyato_2012_Gene_499_297Infantile neuronal ceroid lipofuscinosis: follow-up on a Spanish series
Perez_2012_Am.J.Pathol_180_526Rac1b increases with progressive tau pathology within cholinergic nucleus basalis neurons in Alzheimer's disease
Perez_2012_J.Pharmacol.Exp.Ther_342_335Long-term nicotine exposure depresses dopamine release in nonhuman primate nucleus accumbens
Perez_2012_Microbiology_158_2192Identification of amino acids involved in the hydrolytic activity of lipase LipBL from Marinobacter lipolyticus
Perkins_2012_Inhal.Toxicol_24_539Aerosolized delivery of oxime MMB-4 in combination with atropine sulfate protects against soman exposure in guinea pigs
Pester_2012_J.Bacteriol_194_6300Complete genome sequences of Desulfosporosinus orientis DSM765T, Desulfosporosinus youngiae DSM17734T, Desulfosporosinus meridiei DSM13257T, and Desulfosporosinus acidiphilus DSM22704T
Peterfy_2012_Biochim.Biophys.Acta_1821_790Lipase maturation factor 1: a lipase chaperone involved in lipid metabolism
Peters_2012_Microbes.Infect_14_1196The Chlamydia trachomatis CT149 protein exhibits esterase activity in vitro and catalyzes cholesteryl ester hydrolysis when expressed in HeLa cells
Peters_2012_Phys.Chem.Chem.Phys_14_6764Activity and molecular dynamics relationship within the family of human cholinesterases
Petersen_2012_Environ.Microbiol_14_2661Think pink: photosynthesis, plasmids and the Roseobacter clade
Peterson_2012_Neurobiol.Dis_45_409Adenosine A2a receptor antagonists attenuate striatal adaptations following dopamine depletion
Pethick_2012_J.Bacteriol_194_4476Complete genome sequence of Corynebacterium pseudotuberculosis strain 1/06-A, isolated from a horse in North America
Pethick_2012_J.Bacteriol_194_4736Complete genome sequences of Corynebacterium pseudotuberculosis strains 3/99-5 and 42/02-A, isolated from sheep in Scotland and Australia, respectively
Petrikovics_2012_AAPS.PharmSciTech_13_112Nano-intercalated organophosphorus-hydrolyzing enzymes in organophosphorus antagonism
Petrillo_2012_Biochemistry_51_6164Importance of tetrahedral intermediate formation in the catalytic mechanism of the serine proteases chymotrypsin and subtilisin
Petroianu_2012_Pharmazie_67_874The history of cholinesterase reactivation: hydroxylamine and pyridinium aldoximes
Pevzner_2012_J.Neurol_259_427Anti-LRP4 autoantibodies in AChR- and MuSK-antibody-negative myasthenia gravis
Pezzementi_2012_Mol.Biochem.Parasitol_181_40A tetrameric acetylcholinesterase from the parasitic nematode Dictyocaulus viviparus associates with the vertebrate tail proteins PRiMA and ColQ
Pfeil_2012_Swiss.Med.Wkly_142_0Alzheimer's dementia: budget impact and cost-utility analysis of a combination treatment of a cholinesterase inhibitor and memantine in Switzerland
Philpot_2012_Behav.Brain.Res_230_62Effects of nicotine exposure on locomotor activity and pCREB levels in the ventral striatum of adolescent rats
Phung_2012_J.Bacteriol_194_1835Draft genome of halomonas species strain GFAJ-1 (ATCC BAA-2256)
Phung_2012_J.Bacteriol_194_5153Draft genome sequence of Alcaligenes faecalis subsp. faecalis NCIB 8687 (CCUG 2071)
Pi_2012_PLoS.One_7_e31921Tacrine-6-ferulic acid, a novel multifunctional dimer, inhibits amyloid-beta-mediated Alzheimer's disease-associated pathogenesis in vitro and in vivo
Picciotto_2012_Neuron_76_116Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior
Pielot_2012_Front.Synaptic.Neurosci_4_1SynProt: A Database for Proteins of Detergent-Resistant Synaptic Protein Preparations
Pieper_2012_Life.Sci_91_1113The non-neuronal cholinergic system as novel drug target in the airways
Pilla_2012_J.Biol.Chem_287_44320A Novel SUMO1-specific Interacting Motif in Dipeptidyl Peptidase 9 (DPP9) That Is Important for Enzymatic Regulation
Piner_2012_Environ.Toxicol.Pharmacol_34_473In vivo acetylcholinesterase inhibition in the tissues of spinosad exposed Oreochromis niloticus
Pinto_2012_Org.Lett_14_22786-Deoxyerythronolide B synthase thioesterase-catalyzed macrocyclization is highly stereoselective
Pittet_2012_J.Bacteriol_194_726Genome sequence of Lactobacillus rhamnosus ATCC 8530
Pizarro_2012_Toxicol.Sci_126_497Repeated exposure to sublethal doses of the organophosphorus compound VX activates BDNF expression in mouse brain
Pochini_2012_Life.Sci_91_1013Regulation by physiological cations of acetylcholine transport mediated by human OCTN1 (SLC22A4). Implications in the non-neuronal cholinergic system
Pohanka_2012_Expert.Opin.Ther.Pat_22_871Acetylcholinesterase inhibitors: a patent review (2008 - present)
Pohanka_2012_Iran.Biomed.J_16_156Galantamine effect on tularemia pathogenesis in a BALB/c mouse model
Pohanka_2012_Toxicol.Mech.Methods_22_231Toxicological scoring of Alzheimer's disease drug huperzine in a guinea pig model
Point_2012_Eur.J.Med.Chem_58_452Analysis of the discriminative inhibition of mammalian digestive lipases by 3-phenyl substituted 1,3,4-oxadiazol-2(3H)-ones.
Point_2012_J.Med.Chem_55_10204Synthesis and kinetic evaluation of cyclophostin and cyclipostins phosphonate analogs as selective and potent inhibitors of microbial lipases
Poletika_2012_Integr.Environ.Assess.Manag_8_285A spatially and temporally explicit risk assessment for salmon from a prey base exposed to agricultural insecticides
Pomeroy-Black_2012_Toxicol.In.Vitro_26_759Organophosphorus compound effects on neurotrophin receptors and intracellular signaling
Ponraj_2012_J.Bacteriol_194_6015Genome sequence of the plant growth-promoting rhizobacterium Pseudomonas putida S11
Pontual_2012_Arch.Insect.Biochem.Physiol_79_135Effect of Moringa oleifera flower extract on larval trypsin and acetylcholinesterase activities in Aedes aegypti
Poojary_2012_Indian.J.Exp.Biol_50_110Cold stress interaction on organophosphate insecticide poisoning: age-related assessment in rat cerebral cortex
Popov_2012_J.Control.Release_160_306Site-directed decapsulation of bolaamphiphilic vesicles with enzymatic cleavable surface groups
Portugal_2012_Neurobiol.Learn.Mem_97_482Developmental effects of acute, chronic, and withdrawal from chronic nicotine on fear conditioning
Potter_2012_Psychopharmacology.(Berl)_220_331Manipulation of nicotinic acetylcholine receptors differentially affects behavioral inhibition in human subjects with and without disordered baseline impulsivity
Poulas_2012_J.Neuroimmunol_250_94Anti-MuSK- and anti-AChR-positive myasthenia gravis induced by d-penicillamine
Poulopoulos_2012_Biochem.J_446_321Homodimerization and isoform-specific heterodimerization of neuroligins
Pouryamout_2012_Drugs_72_789Economic evaluation of treatment options in patients with Alzheimer's disease: a systematic review of cost-effectiveness analyses
Prado-Prado_2012_Curr.Top.Med.Chem_12_18433D MI-DRAGON: New Model for the Reconstruction of US FDA Drug- Target Network and Theoretical-Experimental Studies of Inhibitors of Rasagiline Derivatives for AChE
Praisoody_2012_J.Am.Geriatr.Soc_60_805Caution when prescribing cholinesterase inhibitors
Prajapati_2012_J.Bacteriol_194_1264Whole-genome shotgun sequencing of Lactobacillus rhamnosus MTCC 5462, a strain with probiotic potential
Prasad_2012_Neurotoxicol_33_1254Evidence of acrylamide induced oxidative stress and neurotoxicity in Drosophila melanogaster - Its amelioration with spice active enrichment: Relevance to neuropathy
Pregelj_2012_Psychogeriatrics_12_165Safety and tolerability of rivastigmine transdermal patch formulation in newly diagnosed patients with Alzheimer's dementia in naturalistic conditions
Prevost_2012_Nat.Struct.Mol.Biol_19_642A locally closed conformation of a bacterial pentameric proton-gated ion channel
Primozic_2012_Molecules_17_786Preparation of novel meta- and para-substituted N-benzyl protected quinuclidine esters and their resolution with butyrylcholinesterase
Procopio_2012_Antonie.Van.Leeuwenhoek_101_289Insight from the draft genome of Dietzia cinnamea P4 reveals mechanisms of survival in complex tropical soil habitats and biotechnology potential
Proenca_2012_J.Bacteriol_194_3764Draft genome sequence of Serratia sp. strain M24T3, isolated from pinewood disease nematode Bursaphelenchus xylophilus
Proenca_2012_J.Bacteriol_194_4789Draft genome sequence of Pseudomonas sp. strain M47T1, carried by Bursaphelenchus xylophilus isolated from Pinus pinaster
Prokofieva_2012_Anal.Biochem_424_108Microplate biochemical determination of Russian VX: influence of admixtures and avoidance of false negative results
Protasio_2012_PLoS.Negl.Trop.Dis_6_E1455A systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoni
Prufer_2012_Nature_486_527The bonobo genome compared with the chimpanzee and human genomes
Puiu_2012_Anal.Biochem_421_587Kinetic approach of aflatoxin B1-acetylcholinesterase interaction: a tool for developing surface plasmon resonance biosensors
Pundir_2012_Anal.Biochem_429_19Acetylcholinesterase inhibition-based biosensors for pesticide determination: A review
Punga_2012_Curr.Opin.Pharmacol_12_340Signaling and aging at the neuromuscular synapse: lessons learnt from neuromuscular diseases
Puodziukynas_2012_Auton.Neurosci_167_61Radiofrequency catheter ablation of pulmonary vein roots results in axonal degeneration of distal epicardial nerves
Puri_2012_Semin.Pediatr.Surg_21_310Variants of Hirschsprung disease
Purohit_2012_Proc.Natl.Acad.Sci.U.S.A_109_9384Sources of energy for gating by neurotransmitters in acetylcholine receptor channels
Pushparaj_2012_Am.J.Transl.Res_4_422Extinction bursts in rats trained to self-administer nicotine or food in 1-h daily sessions
Puskar_2012_ACS.Chem.Biol_7_841Probing the effects of residues located outside the agonist binding site on drug-receptor selectivity in the nicotinic receptor
Pyun_2012_Genomics.Inform_10_88Interaction Effects of Lipoprotein Lipase Polymorphisms with Lifestyle on Lipid Levels in a Korean Population: A Cross-sectional Study
Qandil_2012_Int.J.Mol.Sci_13_17244Prodrugs of nonsteroidal anti-inflammatory drugs (NSAIDs), more than meets the eye: a critical review
Qi_2012_PLoS.One_7_e38239Comparative geno-plasticity analysis of Mycoplasma bovis HB0801 (Chinese isolate)
Qin_2012_Bioresour.Technol_109_116Improved production of heterologous lipase in Trichoderma reesei by RNAi mediated gene silencing of an endogenic highly expressed gene
Qin_2012_Gene_510_171Genetic variants in epoxide hydrolases modify the risk of oligozoospermia and asthenospermia in Han-Chinese population
Qin_2012_J.Agric.Food.Chem_60_2377Lipase-catalyzed incorporation of different Fatty acids into tripalmitin-enriched triacylglycerols: effect of reaction parameters
Qin_2012_J.Bacteriol_194_1628Draft genome sequence of marine Streptomyces sp. strain W007, which produces angucyclinone antibiotics with a benz[a]anthracene skeleton
Qin_2012_J.Bacteriol_194_3267Genome sequence of proteorhodopsin-containing sea ice bacterium Glaciecola punicea ACAM 611T
Qin_2012_Mol.Biol.Rep_39_8439Cloning of Xuhuai goat lipoprotein lipase gene and the preparation of transgenic sheep
Qin_2012_Zhongguo.Xiu.Fu.Chong.Jian.Wai.Ke.Za.Zhi_26_97[Elementary research of constructive feature and three-dimensional reconstruction of nerve bundles of C7 anterior and posterior division end]
Qiu_2012_Nat.Genet_44_946The yak genome and adaptation to life at high altitude
Qiu_2012_Pestic.Biochem.Physiol_104_201PCR-RFLP methods for detection of insecticide resistance-associated mutations in the house fly (Musca domestica)
Qiu_2012_World.J.Surg_36_2428The clinical study of precise hemihepatectomy guided by middle hepatic vein
Quek_2012_Arch.Neurol_69_582Autoimmune epilepsy: clinical characteristics and response to immunotherapy
Quik_2012_Mov.Disord_27_947Nicotine as a potential neuroprotective agent for Parkinson's disease
Quik_2012_Neuropharmacol_63_450Role for alpha6 nicotinic receptors in l-dopa-induced dyskinesias in parkinsonian mice
Quillen_2012_J.Lipids_2012_189681Novel associations of nonstructural Loci with paraoxonase activity
Quiroga_2012_Biochim.Biophys.Acta_1821_762Liver triacylglycerol lipases
Quiroga_2012_Hepatology_56_2188Deficiency of carboxylesterase 1/esterase-x results in obesity, hepatic steatosis, and hyperlipidemia
Quiroga_2012_PLoS.One_7_e49515Carboxylesterase1/Esterase-x Regulates Chylomicron Production in Mice
Qujeq_2012_Toxicol.Ind.Health_28_291Effects of dichlorvos and carbaryl on the activity of free and immobilized acetylcholinesterase
Quyen_2012_Microb.Cell.Fact_11_29Enhancing functional production of a chaperone-dependent lipase in Escherichia coli using the dual expression cassette plasmid
Rabahi_2012_Neuroreport_23_78Motor performance may be improved by kinesthetic imagery, specific action verb production, and mental calculation
Rabbani_2012_Cell.Biochem.Biophys_62_487pH-Induced molten globule state of Rhizopus niveus lipase is more resistant against thermal and chemical denaturation than its native state
Radakovits_2012_Nat.Commun_3_686Draft genome sequence and genetic transformation of the oleaginous alga Nannochloropis gaditana
Radchenko_2012_Dokl.Biochem.Biophys_443_91Molecular design of O-phosphorylated oximes--selective inhibitors of butyrylcholinesterase
Radek_2012_J.Pharmacol.Exp.Ther_343_736Effects of the novel alpha7 nicotinic acetylcholine receptor agonist ABT-107 on sensory gating in DBA/2 mice: pharmacodynamic characterization
Radic_2012_J.Biol.Chem_287_11798Refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases
Ragozzino_2012_J.Pharmacol.Exp.Ther_340_588The selective M1 muscarinic cholinergic agonist CDD-0102A enhances working memory and cognitive flexibility
Rahigude_2012_Neurosci_226_62Participation of antioxidant and cholinergic system in protective effect of naringenin against type-2 diabetes-induced memory dysfunction in rats
Rahman_2012_Int.J.Mol.Sci_13_92073D structure elucidation of thermostable L2 lipase from Thermophilic Bacillus sp. L2
Raiol_2012_J.Bacteriol_194_5455Complete genome sequence of Mycobacterium massiliense
Rajasethupathy_2012_Cell_149_693A role for neuronal piRNAs in the epigenetic control of memory-related synaptic plasticity
Ramani_2012_Bioprocess.Biosyst.Eng_35_885Production of lipase from Pseudomonas gessardii using blood tissue lipid and thereof for the hydrolysis of blood cholesterol and triglycerides and lysis of red blood cells
Ramos_2012_J.Bacteriol_194_6620Genome sequence of the Corynebacterium pseudotuberculosis Cp316 strain, isolated from the abscess of a Californian horse
Ramos_2012_J.Environ.Sci.Health.B_47_512Cholinesterase characterization in Corbicula fluminea and effects of relevant environmental contaminants: a pesticide (chlorfenvinphos) and a detergent (SDS)
Rampa_2012_ACS.Med.Chem.Lett_3_182The First Dual ChE/FAAH Inhibitors: New Perspectives for Alzheimer's Disease?
Ramsey_2012_Front.Neurosci_6_62Identifying context-specific gene profiles of social, reproductive, and mate preference behavior in a fish species with female mate choice
Rancillac_2012_Curr.Alzheimer.Res_9_1221Impaired neurovascular coupling in the APPxPS1 mouse model of Alzheimer's disease
Ranganathan_2012_Atherosclerosis_221_143The lipoprotein lipase (LPL) S447X gain of function variant involves increased mRNA translation
Rao_2012_Alzheimers.Res.Ther_4_22Ayurvedic medicinal plants for Alzheimer's disease: a review
Rao_2012_Bioinformation_8_276Exploring the role of BCHE in the onset of Diabetes, Obesity and Neurological Disorders
Rashamuse_2012_BMB.Rep_45_14A feruloyl esterase derived from a leachate metagenome library
Rashamuse_2012_J.Mol.Microbiol.Biotechnol_22_277Accessing carboxylesterase diversity from termite hindgut symbionts through metagenomics
Rasoulpour_2012_Toxicol.Sci_127_522A novel mode-of-action mediated by the fetal muscle nicotinic acetylcholine receptor resulting in developmental toxicity in rats
Rastogi_2012_Biogerontology_13_183Prevention of age-associated neurodegeneration and promotion of healthy brain ageing in female Wistar rats by long term use of bacosides
Rau_2012_Environ.Microbiol_14_2200Deletion and acquisition of genomic content during early stage adaptation of Pseudomonas aeruginosa to a human host environment
Rawat_2012_Stand.Genomic.Sci_7_59Complete genome sequence of Terriglobus saanensis type strain SP1PR4(T), an Acidobacteria from tundra soil
Rawlings_2012_Nucleic.Acids.Res_40_D343MEROPS: the database of proteolytic enzymes, their substrates and inhibitors
Raza_2012_Chem.Biol.Drug.Des_80_605Synthesis and Biological Evaluation of 3-thiazolocoumarinyl Schiff-base Derivatives as Cholinesterase Inhibitors
Raza_2012_ISRN.Pharmacol_2012_707932Pharmacological Evaluation and Docking Studies of 3-Thiadiazolyl- and Thioxo-1,2,4-triazolylcoumarin Derivatives as Cholinesterase Inhibitors
Razzaghi_2012_Front.Genet_3_89Population-Based Resequencing of LIPG and ZNF202 Genes in Subjects with Extreme HDL Levels
Redondo-Nieto_2012_J.Bacteriol_194_1273Genome sequence of the biocontrol strain Pseudomonas fluorescens F113
Rees_2012_Forensic.Sci.Int_217_182The effect of sodium fluoride preservative and storage temperature on the stability of cocaine in horse blood, sheep vitreous and deer muscle
Regal_2012_Mol.Genet.Metab_107_614Two novel deletions in hypotonia-cystinuria syndrome
Regnault-Roger_2012_Annu.Rev.Entomol_57_405Essential oils in insect control: low-risk products in a high-stakes world
Rehdorf_2012_Appl.Microbiol.Biotechnol_93_1119Pseudomonas putida esterase contains a GGG(A)X-motif confering activity for the kinetic resolution of tertiary alcohols
Rehman_2012_Pak.J.Pharm.Sci_25_809Synthesis, characterization and biological screening of sulfonamides derived form 2-phenylethylamine
Reid_2012_PLoS.Pathog_8_e1002567Comparative genomics of the apicomplexan parasites Toxoplasma gondii and Neospora caninum: Coccidia differing in host range and transmission strategy
Reiner_2012_Handb.Exp.Pharmacol_208_61Muscarinic receptor trafficking
Reisenberg_2012_Philos.Trans.R.Soc.Lond.B.Biol.Sci_367_3264The diacylglycerol lipases: structure, regulation and roles in and beyond endocannabinoid signalling
Reiss_2012_Regul.Toxicol.Pharmacol_63_124Acetylcholinesterase inhibition dose-response modeling for chlorpyrifos and chlorpyrifos-oxon
Rejon_2012_Ann.Bot_110_1035Profiling and functional classification of esterases in olive (Olea europaea) pollen during germination
Rengachari_2012_Biochim.Biophys.Acta_1821_1012The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes
Reny_2012_J.Thromb.Haemost_10_1242Influence of the paraoxonase-1 Q192R genetic variant on clopidogrel responsiveness and recurrent cardiovascular events: a systematic review and meta-analysis
Reyes-Duarte_2012_Methods.Mol.Biol_861_101Functional-based screening methods for lipases, esterases, and phospholipases in metagenomic libraries
Reyes_2012_Acta.Neuropathol_123_119Selective tau tyrosine nitration in non-AD tauopathies
Rezin_2012_Metab.Brain.Dis_27_453Inhibition of acetylcholinesterase activity in brain and behavioral analysis in adult rats after chronic administration of fenproporex
Rezonzew_2012_Am.J.Physiol.Renal.Physiol_303_F304Nicotine exposure and the progression of chronic kidney disease: role of the alpha7-nicotinic acetylcholine receptor
Rezvani_2012_Eur.J.Pharmacol_682_110Effects of sazetidine-A, a selective alpha4beta2* nicotinic receptor desensitizing agent, on body temperature regulation in mice and rats
Rhoades_2012_Pharm.Res_29_972Prediction and in vitro evaluation of selected protease inhibitor antiviral drugs as inhibitors of carboxylesterase 1: a potential source of drug-drug interactions
Riaz_2012_J.Asian.Nat.Prod.Res_14_1149Cholinesterase inhibitory constituents from Ficus bengalensis
Ribas_2012_Clin.Biochem_45_77Reduction of butyrylcholinesterase activity in plasma from patients with disorders of propionate metabolism is prevented by treatment with L-carnitine and protein restriction
Ribeiro_2012_Insect.Biochem.Mol.Biol_42_332The sialotranscriptome of Antricola delacruzi female ticks is compatible with non-hematophagous behavior and an alternative source of food
Ribeiro_2012_J.Med.Entomol_49_563An insight into the sialotranscriptome of Triatoma rubida (Hemiptera: Heteroptera)
Ribeiro_2012_PLoS.ONE_7_e44612An insight into the sialotranscriptome of the cat flea, Ctenocephalides felis
Ribitsch_2012_J.Biotechnol_157_140Extracellular serine proteases from Stenotrophomonas maltophilia: Screening, isolation and heterologous expression in E. coli
Ribitsch_2012_Polymers_4_617A New Esterase from Thermobifida halotolerans Hydrolyses Polyethylene Terephthalate (PET) and Polylactic Acid (PLA)
Ricaldi_2012_PLoS.Negl.Trop.Dis_6_E1853Whole genome analysis of Leptospira licerasiae provides insight into leptospiral evolution and pathogenicity
Riccombeni_2012_PLoS.ONE_7_e35750Sequence and analysis of the genome of the pathogenic yeast Candida orthopsilosis
Rice_2012_Addiction_107_2019CHRNB3 is more strongly associated with Fagerstrom test for cigarette dependence-based nicotine dependence than cigarettes per day: phenotype definition changes genome-wide association studies results
Richards_2012_Arch.Insect.Biochem.Physiol_79_61Salivary secretions from the ectoparasitic wasp, Eulophus pennicornis contain hydrolases, and kill host hemocytes by apoptosis
Richards_2012_Nano.Lett_12_3690Live-cell imaging of single receptor composition using zero-mode waveguide nanostructures
Richman_2012_Arch.Neurol_69_453Acute severe animal model of anti-muscle-specific kinase myasthenia: combined postsynaptic and presynaptic changes
Richter_2012_J.Am.Chem.Soc_134_16197Computational design of catalytic dyads and oxyanion holes for ester hydrolysis
Riedel_2012_Stand.Genomic.Sci_7_107Genome sequence of the Antarctic rhodopsins-containing flavobacterium Gillisia limnaea type strain (R-8282(T))
Riedel_2012_Stand.Genomic.Sci_7_120Genome sequence of the orange-pigmented seawater bacterium Owenweeksia hongkongensis type strain (UST20020801(T))
Riederer_2012_J.Clin.Med.Res_4_49Endothelial Lipase Plasma Levels are Increased in Patients With Significant Carotid Artery Stenosis and History of Neurological Impairment
Rinwa_2012_Brain.Res_1488_38Piperine potentiates the protective effects of curcumin against chronic unpredictable stress-induced cognitive impairment and oxidative damage in mice
Rinwa_2012_Indian.J.Pharmacol_44_366Pharmacological investigation of memory restorative effect of riluzole in mice
Rissone_2012_Arterioscler.Thromb.Vasc.Biol_32_1563The synaptic proteins beta-neurexin and neuroligin synergize with extracellular matrix-binding vascular endothelial growth factor a during zebrafish vascular development
Rivera_2012_Methods.Mol.Biol_861_115Plant lipases: partial purification of Carica papaya lipase
Robbins_2012_Cell.Rep_2_878Lysine deacetylases Hda1 and Rpd3 regulate Hsp90 function thereby governing fungal drug resistance
Roberts_2012_Alzheimers.Res.Ther_4_50Simulations of symptomatic treatments for Alzheimer's disease: computational analysis of pathology and mechanisms of drug action
Roberts_2012_Chem.Res.Toxicol_25_1435In vitro metabolism of the brominated flame retardants 2-ethylhexyl-2,3,4,5-tetrabromobenzoate (TBB) and bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate (TBPH) in human and rat tissues
Roberts_2012_J.Inherit.Metab.Dis_35_847Combination small molecule PPT1 mimetic and CNS-directed gene therapy as a treatment for infantile neuronal ceroid lipofuscinosis
Roberts_2012_Pediatrics_130_e1765Pesticide exposure in children
Rocha-Resende_2012_J.Mol.Cell.Cardiol_53_206Non-neuronal cholinergic machinery present in cardiomyocytes offsets hypertrophic signals
Rode_2012_Brain.Res_1458_67Positive allosteric modulation of alpha4beta2 nAChR agonist induced behaviour
Rodrigues_2012_J.Environ.Monit_14_1638Effects of anticholinesterase drugs on biomarkers and behavior of pumpkinseed, Lepomis gibbosus (Linnaeus, 1758)
Rodrigues_2012_Sci.Total.Environ_443C_454Exposure of Carcinus maenas to waterborne fluoranthene: Accumulation and multibiomarker responses
Rodriguez_2012_Rev.Esp.Geriatr.Gerontol_47_228[Pharmacological treatment of dementia: When, how and for how long. Recommendations of the Working Group on Dementia of the Catalan Society of Geriatrics and Gerontology]
Rogers_2012_Am.J.Med.Genet.A_158A_1135Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure
Rogers_2012_Brain.Behav_2_628The expression of nicotinic receptor alpha7 during cochlear development
Rogers_2012_J.Pharmacokinet.Pharmacodyn_39_479Combining patient-level and summary-level data for Alzheimer's disease modeling and simulation: a beta regression meta-analysis
Rogers_2012_PLoS.One_7_e36467Nicotinic receptor Alpha7 expression during tooth morphogenesis reveals functional pleiotropy
Roh_2012_J.Bacteriol_194_2773Genome sequence of Vibrio sp. strain EJY3, an agarolytic marine bacterium metabolizing 3,6-anhydro-L-galactose as a sole carbon source
Rohde_2012_J.Biol.Chem_287_4248Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine alpha4beta2 receptors: unique role of halogen bonding revealed
Rohe_2012_Microb.Cell.Fact_11_144An automated workflow for enhancing microbial bioprocess optimization on a novel microbioreactor platform
Rohnert_2012_J.Neuroinflammation_9_44Dipeptidyl peptidase IV, aminopeptidase N and DPIV/APN-like proteases in cerebral ischemia
Rojas_2012_J.Bacteriol_194_3023Draft genome of a Brazilian avian-pathogenic Escherichia coli strain and in silico characterization of virulence-related genes
Rojsanga_2012_Life.Sci_91_107The effect of crebanine on memory and cognition impairment via the alpha-7 nicotinic acetylcholine receptor
Rokyta_2012_BMC.Genomics_13_312The venom-gland transcriptome of the eastern diamondback rattlesnake (Crotalus adamanteus)
Rolinski_2012_Cochrane.Database.Syst.Rev__CD006504Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease
Rolland_2012_J.Am.Med.Dir.Assoc_13_407 e7Psychotropic drug consumption at admission and discharge of nursing home residents
Romdhane_2012_Gene_494_112Gene cloning and molecular characterization of the Talaromyces thermophilus lipase catalyzed efficient hydrolysis and synthesis of esters
Romero_2012_Chem.Commun.(Camb)_48_9053Semisynthetic peptide-lipase conjugates for improved biotransformations
Ron_2012_Cereb.Cortex_22_2519Overexpression of PKMzeta alters morphology and function of dendritic spines in cultured cortical neurons
Ronco_2012_ChemMedChem_7_400Huprine derivatives as sub-nanomolar human acetylcholinesterase inhibitors: from rational design to validation by X-ray crystallography
Rosenbaum_2012_Arch.Biochem.Biophys_517_104Effects of hydrostatic pressure on the quaternary structure and enzymatic activity of a large peptidase complex from Pyrococcus horikoshii
Rosenbaum_2012_Environ.Toxicol.Chem_31_2311Response of biomarkers in amphibian larvae to in situ exposures in a fruit-producing region in North Patagonia, Argentina
Rosenblat_2012_Biofactors_38_292VLDL triglycerides inhibit HDL-associated paraoxonase 1 (PON1) activity: in vitro and in vivo studies
Rosenblat_2012_Biofactors_38_458Triglyceride accumulation in macrophages upregulates paraoxonase 2 (PON2) expression via ROS-mediated JNK/c-Jun signaling pathway activation
Rosenson_2012_J.Lipid.Res_53_1767Modulation of oxidative stress, inflammation, and atherosclerosis by lipoprotein-associated phospholipase A2
Rosewarne_2012_J.Bacteriol_194_4130Draft genome sequence of Treponema sp. strain JC4, a novel spirochete isolated from the bovine rumen
Ross_2012_Arch.Biochem.Biophys_522_44Examination of the carboxylesterase phenotype in human liver
Rotariu_2012_Anal.Chim.Acta_748_81A rational design of the multiwalled carbon nanotube-7,7,8,8-tetracyanoquinodimethan sensor for sensitive detection of acetylcholinesterase inhibitors
Roumeliotis_2012_J.Exp.Bot_63_4539The effects of auxin and strigolactones on tuber initiation and stolon architecture in potato
Roux_2012_Med.Sci.(Paris)_28_44[Unexpected link between Huntington disease and Rett syndrome]
Roux_2012_Neurobiol.Dis_45_786Modification of Mecp2 dosage alters axonal transport through the Huntingtin/Hap1 pathway
Roy_2012_PLoS.One_7_e39997An analysis of the myocardial transcriptome in a mouse model of cardiac dysfunction with decreased cholinergic neurotransmission
Rubio_2012_J.Neurosci.Res_90_13Epigenetic control of somatostatin and cortistatin expression by beta amyloid peptide
Ruckert_2012_J.Bacteriol_194_5997Draft genome sequence of Bacillus anthracis UR-1, isolated from a German heroin user
Ruckert_2012_Stand.Genomic.Sci_7_284Genome sequence of the halotolerant bacterium Corynebacterium halotolerans type strain YIM 70093(T) (= DSM 44683(T))
Rucktooa_2012_J.Biol.Chem_287_23283Structural characterization of binding mode of smoking cessation drugs to nicotinic acetylcholine receptors through study of ligand complexes with acetylcholine-binding protein
Rudakova_2012_Dokl.Biochem.Biophys_443_81Esterase profile of O-phosphorylated ethyltrifluorolactates in prediction of their therapeutic and toxic effects
Ruf_2012_J.Med.Chem_55_7636Novel beta-amino acid derivatives as inhibitors of cathepsin A.
Ruggiero_2012_ACS.Chem.Neurosci_3_767Nonoisotopic assay for the presynaptic choline transporter reveals capacity for allosteric modulation of choline uptake
Ruiz_2012_Life.Sci_91_986Critical metabolic roles of beta-cell M3 muscarinic acetylcholine receptors
Rull_2012_Atherosclerosis_220_545Serum paraoxonase-3 concentration is associated with insulin sensitivity in peripheral artery disease and with inflammation in coronary artery disease
Rungsanpanya_2012_J.Med.Assoc.Thai_95_1081Clinical practice with antidementia drugs in a geriatric clinic
Ruslan_2012_Int.J.Mol.Sci_13_943Improvement of thermal stability via outer-loop ion pair interaction of mutated T1 lipase from Geobacillus zalihae strain T1
Russ_2012_Cochrane.Database.Syst.Rev__CD009132Cholinesterase inhibitors for mild cognitive impairment
Russ_2012_Int.J.Geriatr.Psychiatry_27_844Cognitive and behavioural predictors of survival in Alzheimer disease: results from a sample of treated patients in a tertiary-referral memory clinic
Russo_2012_Life.Sci_91_1087Nicotinic receptor and tobacco-related cancer
Ruzzini_2012_Biochemistry_51_5831The Catalytic Serine of meta-Cleavage Product Hydrolases Is Activated Differently for C-O Bond Cleavage Than for C-C Bond Cleavage.
Ruzzini_2012_J.Am.Chem.Soc_134_4615Identification of an Acyl-Enzyme Intermediate in a meta-Cleavage Product Hydrolase Reveals the Versatility of the Catalytic Triad
Ryabtsova_2012_Bioorg.Med.Chem.Lett_22_3412Acylated Gly-(2-cyano)pyrrolidines as inhibitors of fibroblast activation protein (FAP) and the issue of FAP/prolyl oligopeptidase (PREP)-selectivity
Ryder_2012_Chem.Res.Toxicol_25_2138Insights into the Novel Hydrolytic Mechanism of a Diethyl 2-Phenyl-2-(2-arylacetoxy)methyl Malonate Ester-Based Microsomal Triglyceride Transfer Protein (MTP) Inhibitor
Ryu_2012_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_68_560Identification, crystallization and preliminary X-ray diffraction analysis of esterase A from Caulobacter crescentus CB15, a family VIII lipolytic enzyme
Sabbagh_2012_Int.J.Neurosci_122_742Administration of donepezil does not rescue galanin-induced spatial learning deficits
Sabunciyan_2012_PLoS.One_7_e34451Genome-wide DNA methylation scan in major depressive disorder
Saez_2012_Endocr.Metab.Immune.Disord.Drug.Targets_12_274Possible usefulness of growth hormone/insulin-like growth factor-I axis in Alzheimer's disease treatment
Saha_2012_Hum.Mol.Genet_21_2233The blood-brain barrier is disrupted in a mouse model of infantile neuronal ceroid lipofuscinosis: amelioration by resveratrol
Sahin_2012_Genet.Test.Mol.Biomarkers_16_423Investigation of a possible relationship between EPHX1 gene polymorphisms and colorectal cancer in Turkish society
Said_2012_World.J.Clin.Oncol_3_104Inhibition of N-Myc down regulated gene 1 in in vitro cultured human glioblastoma cells
Saidi_2012_Hum.Exp.Toxicol_31_518Effect of sweet almond oil on survival rate and plasma cholinesterase activity of aluminum phosphide-intoxicated rats
Sailaja_2012_Proc.Natl.Acad.Sci.U.S.A_109_E3687Stress-induced epigenetic transcriptional memory of acetylcholinesterase by HDAC4
Saini_2012_Nucleic.Acids.Res_40_10832Massive gene acquisitions in Mycobacterium indicus pranii provide a perspective on mycobacterial evolution
Saito_2012_Mol.Genet.Metab_105_244Structural bases of Wolman disease and cholesteryl ester storage disease
Sakai_2012_Appl.Microbiol.Biotechnol_93_2011Heterologous expression system in Aspergillus oryzae for fungal biosynthetic gene clusters of secondary metabolites
Sakkiah_2012_Acta.Pharmacol.Sin_33_964Pharmacophore-based virtual screening and density functional theory approach to identifying novel butyrylcholinesterase inhibitors
Saldanha_2012_Life.Sci_91_1017Fibrinogen effects on erythrocyte nitric oxide mobilization in presence of acetylcholine
Salomone_2012_Br.J.Clin.Pharmacol_73_504New pharmacological strategies for treatment of Alzheimer's disease: focus on disease modifying drugs
Salovich_2012_Bioorg.Med.Chem.Lett_22_5084Discovery of N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)isonicatinamide, ML293, as a novel, selective and brain penetrant positive allosteric modulator of the muscarinic 4 (M4) receptor
Salvaterra_2012_Aquat.Toxicol_128-129C_190Biochemical and metabolic effects of a short-term exposure to nanoparticles of titanium silicate in tadpoles of Pelophylax perezi (Seoane)
Samadi_2012_Eur.J.Med.Chem_52_251Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine
Samadi_2012_Eur.J.Med.Chem_57C_296Pyridonepezils, new dual AChE inhibitors as potential drugs for the treatment of Alzheimer's disease: Synthesis, biological assessment, and molecular modeling
Sams_2012_Bioorg.Med.Chem.Lett_22_5134Hit-to-lead investigation of a series of novel combined dopamine D2 and muscarinic M1 receptor ligands with putative antipsychotic and pro-cognitive potential
Sanchez-Gonzalez_2012_Methods.Mol.Biol_861_53Study of new feruloyl esterases to understand lipase evolution: the case of Bacillus flexus
Sanchez_2012_Microbiol.Res_167_317A Pseudomonas aeruginosa PAO1 acetylcholinesterase is encoded by the PA4921 gene and belongs to the SGNH hydrolase family
Sandstrom_2012_Proc.Natl.Acad.Sci.U.S.A_109_78Combinatorial reshaping of the Candida antarctica lipase A substrate pocket for enantioselectivity using an extremely condensed library
Sang_2012_J.Steroid.Biochem.Mol.Biol_129_22Identification of a new steroid degrading bacterial strain H5 from the Baltic Sea and isolation of two estradiol inducible genes
Sangal_2012_J.Bacteriol_194_4738Draft genome sequence of Corynebacterium diphtheriae biovar intermedius NCTC 5011
Sankhwar_2012_Hum.Exp.Toxicol_31_606Impaired cholinergic mechanisms following exposure to monocrotophos in young rats
Sans_2012_Clin.Chem.Lab.Med_50_1409Monocyte chemoattractant protein-1 and paraoxonase-1 and 3 levels in patients with sepsis treated in an intensive care unit: a preliminary report
Santo_2012_J.Bacteriol_194_1623Draft genome sequence of Pseudomonas psychrotolerans L19, isolated from copper alloy coins
Santos_2012_Chemosphere_89_1118Atrazine promotes biochemical changes and DNA damage in a Neotropical fish species
Santos_2012_Exp.Neurol_233_767Probucol, a lipid-lowering drug, prevents cognitive and hippocampal synaptic impairments induced by amyloid beta peptide in mice
Santos_2012_PLoS.One_7_e33975Characterization of cholinesterases in plasma of three Portuguese native bird species: application to biomonitoring
Santos_2012_Pharm.Biol_50_919In vitro and ex vivo anticholinesterase activities of Erythrina velutina leaf extracts
Santos_2012_Toxicology_292_90The inhibitory effect of manganese on acetylcholinesterase activity enhances oxidative stress and neuroinflammation in the rat brain
Saravanan_2012_Chem.Biol.Drug.Des_79_1056Potential selective inhibitors against Rv0183 of Mycobacterium tuberculosis targeting host lipid metabolism
Saravanan_2012_J.Mol.Graph.Model_38C_235Targeting essential cell wall lipase Rv3802c for potential therapeutics against tuberculosis
Saricicek_2012_Am.J.Psychiatry_169_851Persistent beta2*-nicotinic acetylcholinergic receptor dysfunction in major depressive disorder
Sarkar_2012_J.Lipids_2012_610937Solubilization and humanization of paraoxonase-1
Sarto-Jackson_2012_J.Biol.Chem_287_14201The cell adhesion molecule neuroplastin-65 is a novel interaction partner of gamma-aminobutyric acid type A receptors
Sass_2012_J.Bacteriol_194_2107Genome sequence of Staphylococcus aureus VC40, a vancomycin- and daptomycin-resistant strain, to study the genetics of development of resistance to currently applied last-resort antibiotics
Sato_2012_Drug.Metab.Dispos_40_902Conclusive identification of the oxybutynin-hydrolyzing enzyme in human liver
Sato_2012_Nature_485_635The tomato genome sequence provides insights into fleshy fruit evolution
Satou_2012_Methods.Enzymol_514_165The study of ghrelin deacylation enzymes
Savel_2012_Vasc.Health.Risk.Manag_8_357Very low levels of HDL cholesterol and atherosclerosis, a variable relationship--a review of LCAT deficiency
Savinainen_2012_Acta.Physiol.(Oxf)_204_267The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2-arachidonoylglycerol signalling through cannabinoid receptors
Savonenko_2012_Neuropsychopharmacology_37_261Alzheimer's therapeutics: translation of preclinical science to clinical drug development
Saw_2012_Stand.Genomic.Sci_6_84Complete genome sequencing and analysis of Saprospira grandis str. Lewin, a predatory marine bacterium
Sawada_2012_Biosci.Biotechnol.Biochem_76_544An unusual spliced variant of DELLA protein, a negative regulator of gibberellin signaling, in lettuce
Sawyer_2012_Toxicology_294_85Non-cholinergic intervention of sarin nerve agent poisoning
Scaffidi_2012_Bioorg.Med.Chem.Lett_22_3743Exploring the molecular mechanism of karrikins and strigolactones
Scaffidi_2012_Org.Biomol.Chem_10_4069Solar irradiation of the seed germination stimulant karrikinolide produces two novel head-to-head cage dimers
Scaini_2012_Mol.Neurobiol_45_279Evaluation of acetylcholinesterase in an animal model of maple syrup urine disease
Scally_2012_Nature_483_169Insights into hominid evolution from the gorilla genome sequence
Scarcella_2012_Mol.Biochem.Parasitol_185_151Increase of carboxylesterase activity in Fasciola hepatica recovered from triclabendazole treated sheep
Schaaf_2012_Eur.J.Hum.Genet_20_1240Phenotypic spectrum and genotype-phenotype correlations of NRXN1 exon deletions
Schenk_2012_Acc.Chem.Res_45_1593Binuclear metallohydrolases: complex mechanistic strategies for a simple chemical reaction
Scherman_2012_Bioorg.Med.Chem_20_3255Screening a library of 1600 adamantyl ureas for anti-Mycobacterium tuberculosis activity in vitro and for better physical chemical properties for bioavailability
Scherzer-Attali_2012_Neurobiol.Dis_46_663Naphthoquinone-tyrptophan reduces neurotoxic Abeta*56 levels and improves cognition in Alzheimer's disease animal model
Schindler_2012_Future.Med.Chem_4_163Accelerating cocaine metabolism as an approach to the treatment of cocaine abuse and toxicity
Schinke_2012_Int.Microbiol_15_1Screening Brazilian Macrophomina phaseolina isolates for alkaline lipases and other extracellular hydrolases
Schittmayer_2012_Mass.Spectrom.Rev_31_570Lipolytic proteomics
Schmeisser_2012_Nature_486_256Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2
Schmitz_2012_Mol.Cell.Biochem_361_281Chronic methylphenidate administration alters antioxidant defenses and butyrylcholinesterase activity in blood of juvenile rats
Schneider_2012_Eukaryot.Cell_11_1582Draft genome sequence of Wickerhamomyces ciferrii NRRL Y-1031 F-60-10
Schneider_2012_FEMS.Yeast.Res_12_382Genome sequence of Wickerhamomyces anomalus DSM 6766 reveals genetic basis of biotechnologically important antimicrobial activities
Schneider_2012_Int.Psychogeriatr_24_171Could cholinesterase inhibitors be harmful over the long term?
Schneider_2012_N.Engl.J.Med_366_957Discontinuing donepezil or starting memantine for Alzheimer's disease
Schnell_2012_PLoS.One_7_e48045Neuroligin-1 overexpression in newborn granule cells in vivo
Schock_2012_Zebrafish_9_169The Effects of Carbaryl on the Development of Zebrafish (Danio rerio) Embryos
Scholler_2012_J.Clin.Endocrinol.Metab_97_2466Phospholipid transfer protein is differentially expressed in human arterial and venous placental endothelial cells and enhances cholesterol efflux to fetal HDL
Scholze_2012_J.Neurochem_121_551Subunit composition of alpha5-containing nicotinic receptors in the rodent habenula
Schopfer_2012_Drug.Test.Anal_4_246Analytical approaches for monitoring exposure to organophosphorus and carbamate agents through analysis of protein adducts
Schork_2012_J.Bacteriol_194_5144Genome sequence of a Neisseria meningitidis capsule null locus strain from the clonal complex of sequence type 198
Schrimpf_2012_Bioorg.Med.Chem.Lett_22_1633SAR of alpha7 nicotinic receptor agonists derived from tilorone: exploration of a novel nicotinic pharmacophore
Schroder_2012_BMC.Genomics_13_141Complete genome sequence, lifestyle, and multi-drug resistance of the human pathogen Corynebacterium resistens DSM 45100 isolated from blood samples of a leukemia patient
Schubert_2012_Life.Sci_91_1048Expression of the non-neuronal cholinergic system in human knee synovial tissue from patients with rheumatoid arthritis and osteoarthritis
Schuldes_2012_J.Bacteriol_194_4483Complete genome sequence of the broad-host-range strain Sinorhizobium fredii USDA257
Schultz_2012_Toxicol.Appl.Pharmacol_259_376The anticholinergic and antiglutamatergic drug caramiphen reduces seizure duration in soman-exposed rats: synergism with the benzodiazepine diazepam
Schwartz_2012_Curr.Pharm.Biotechnol_13_1971Reactive skin decontamination lotion (RSDL) for the decontamination of chemical warfare agent (CWA) dermal exposure
Schwarz_2012_Curr.Opin.Psychiatry_25_542Pharmacological treatment of dementia
Schweikert_2012_Cell.Death.Differ_19_1549PON3 is upregulated in cancer tissues and protects against mitochondrial superoxide-mediated cell death
Schweikert_2012_J.Lipids_2012_352857Paraoxonases-2 and -3 Are Important Defense Enzymes against Pseudomonas aeruginosa Virulence Factors due to Their Anti-Oxidative and Anti-Inflammatory Properties
Scott_2012_J.Am.Mosq.Control.Assoc_28_323Comparison of biochemical and molecular tests for detecting insecticide resistance due to insensitive acetylcholinesterase in Culex quinquefasciatus
Scremin_2012_J.Neurotrauma_29_2457Acetylcholinesterase inhibition interacts with training to reverse spatial learning deficits after cortical impact injury
Searl_2012_Eur.J.Pharmacol_685_38Evidence for constitutively-active adenosine receptors at mammalian motor nerve endings
Searl_2012_J.Pharmacol.Exp.Ther_342_312Modulation of purinergic neuromuscular transmission by phorbol dibutyrate is independent of protein kinase C in murine urinary bladder
Seeger_2012_Toxicology_294_80Restoration of soman-blocked neuromuscular transmission in human and rat muscle by the bispyridinium non-oxime MB327 in vitro
Seeliger_2012_J.Biol.Chem_287_7990Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis
Seepersaud_2012_J.Bacteriol_194_5564The accessory Sec protein Asp2 modulates GlcNAc deposition onto the serine-rich repeat glycoprotein GspB
Seiler_2012_Prog.Retin.Eye.Res_31_661Cell replacement and visual restoration by retinal sheet transplants
Seitz_2012_Int.Psychogeriatr__1Pharmacological treatments for neuropsychiatric symptoms of dementia in long-term care: a systematic review
Sekizuka_2012_BMC.Microbiol_12_72Corynebacterium ulcerans 0102 carries the gene encoding diphtheria toxin on a prophage different from the C. diphtheriae NCTC 13129 prophage
Sekutor_2012_Bioorg.Chem_41-42_28Adamantane-substituted guanylhydrazones: novel inhibitors of butyrylcholinesterase
Sellers_2012_Handb.Exp.Pharmacol_208_375Muscarinic agonists and antagonists: effects on the urinary bladder
Selmi_2012_Environ.Toxicol.Pharmacol_34_753Oxidative stress and cholinesterase inhibition in plasma, erythrocyte and brain of rats' pups following lactational exposure to malathion
Seltman_2012_CNS.Drugs_26_841Frontotemporal lobar degeneration: epidemiology, pathology, diagnosis and management
Selvin_2012_Microb.Cell.Fact_11_72Isolation identification and biochemical characterization of a novel halo-tolerant lipase from the metagenome of the marine sponge Haliclona simulans
Semenova_2012_Nicotine.Tob.Res_14_1346Mice lacking the beta4 subunit of the nicotinic acetylcholine receptor show memory deficits, altered anxiety- and depression-like behavior, and diminished nicotine-induced analgesia
Sendi_2012_Hepat.Mon_12_312Dual Role of miR-122 in Molecular Pathogenesis of Viral Hepatitis
Sengul_2012_Anat.Rec.(Hoboken)_295_837Cytoarchitecture of the spinal cord of the postnatal (P4) mouse
Senol_2012_Int.J.Food.Sci.Nutr_63_553Antioxidant and anticholinesterase effects of frequently consumed cereal grains using in vitro test models
Senol_2012_Int.J.Food.Sci.Nutr_63_802An in vitro perspective to cholinesterase inhibitory and antioxidant activity of five Gentiana species and Gentianella caucasea
Seo_2012_Mol.Biol.Rep_39_157A self-contained enzyme activating prodrug cytotherapy for preclinical melanoma
Seong_2012_Insect.Mol.Biol_21_149Identification and characterization of three cholinesterases from the common bed bug, Cimex lectularius
Sermboonpaisarn_2012_Fitoterapia_83_780Potent and selective butyrylcholinesterase inhibitors from Ficus foveolata
Servin-Garciduenas_2012_J.Bacteriol_194_6310Genome sequence of Rhizobium sp. strain CCGE510, a symbiont isolated from nodules of the endangered wild bean Phaseolus albescens
Setoguchi_2012_Cytokine_57_238Effects of a peripheral cholinesterase inhibitor on cytokine production and autonomic nervous activity in a rat model of sepsis
Seyednejad_2012_Biomaterials_33_4309In vivo biocompatibility and biodegradation of 3D-printed porous scaffolds based on a hydroxyl-functionalized poly(sigma-caprolactone)
Shacka_2012_Brain.Res.Bull_88_43Mouse models of neuronal ceroid lipofuscinoses: useful pre-clinical tools to delineate disease pathophysiology and validate therapeutics
Shah_2012_Curr.Alzheimer.Res_9_1069Low 25OH Vitamin D2 Levels Found in Untreated Alzheimer's Patients, Compared to Acetylcholinesterase-Inhibitor Treated and Controls
Shahsavar_2012_PLoS.One_7_e40757Crystal structure of Lymnaea stagnalis AChBP complexed with the potent nAChR antagonist DHbetaE suggests a unique mode of antagonism
Shakil_2012_CNS.Neurol.Disord.Drug.Targets_11_142Molecular interaction of the antineoplastic drug, methotrexate with human brain acetylcholinesterase: a docking study
Shankar_2012_J.Bacteriol_194_4479Genome sequence of the plant growth-promoting bacterium Enterobacter cloacae GS1
Shao_2012_Appl.Environ.Microbiol_78_2034Identification of the herboxidiene biosynthetic gene cluster in Streptomyces chromofuscus ATCC 49982
Shapiro_2012_PLoS.One_7_e49440Remarkable diversity in the enzymes catalyzing the last step in synthesis of the pimelate moiety of biotin
Sharma_2012_Bioorg.Med.Chem_20_6821O-Aryl alpha,beta-d-ribofuranosides: synthesis & highly efficient biocatalytic separation of anomers and evaluation of their Src kinase inhibitory activity
Sharma_2012_Can.J.Microbiol_58_982Kinetics of medium-chain-length polyhydroxyalkanoate production by a novel isolate of Pseudomonas putida LS46
Sharma_2012_Gene_491_264Engineering of a metagenome derived lipase toward thermal tolerance: effect of asparagine to lysine mutation on the protein surface
Sharma_2012_J.Bacteriol_194_1279Genome sequence of Brevibacillus laterosporus strain GI-9
Sharma_2012_J.Bacteriol_194_2395Genome sequence of Xanthomonas axonopodis pv. punicae strain LMG 859
Sharma_2012_J.Hazard.Mater_221-222_275Organochlorine pesticide, endosulfan induced cellular and organismal response in Drosophila melanogaster
Sharma_2012_Mol.Biol.Rep_39_2795Characterization of a thermostable lipase showing loss of secondary structure at ambient temperature
Sharma_2012_Pharmacol.Biochem.Behav_101_239Neuroprotective effect of RO-20-1724-a phosphodiesterase4 inhibitor against intracerebroventricular streptozotocin induced cognitive deficit and oxidative stress in rats
Sharma_2012_Pharmacol.Biochem.Behav_102_101Experimental hypertension induced vascular dementia: pharmacological, biochemical and behavioral recuperation by angiotensin receptor blocker and acetylcholinesterase inhibitor
Sharma_2012_Pharmacol.Biochem.Behav_103_821Pharmacological inhibition of inducible nitric oxide synthase (iNOS) and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, convalesce behavior and biochemistry of hypertension induced vascular dementia in rats
Sharma_2012_Prog.Neuropsychopharmacol.Biol.Psychiatry_38_207Salutary effect of NFkappaB inhibitor and folacin in hyperhomocysteinemia-hyperlipidemia induced vascular dementia
Sharma_2012_Psychopharmacology.(Berl)_223_307Defensive effect of natrium diethyldithiocarbamate trihydrate (NDDCT) and lisinopril in DOCA-salt hypertension-induced vascular dementia in rats
Shen_2012_Analyst_137_2119A new continuous fluorometric assay for acetylcholinesterase activity and inhibitor screening with emissive core-shell silica particles containing tetraphenylethylene fluorophore
Shen_2012_Infect.Immun_80_243LipC (Rv0220) is an immunogenic cell surface esterase of Mycobacterium tuberculosis
Shen_2012_Int.J.Clin.Exp.Pathol_5_900The protection of acetylcholinesterase inhibitor on beta-amyloid-induced the injury of neurite outgrowth via regulating axon guidance related genes expression in neuronal cells
Shen_2012_J.Clin.Invest_122_2613Myasthenic syndrome AChRalpha C-loop mutant disrupts initiation of channel gating
Shen_2012_J.Med.Chem_55_1789Discovery of inhibitors of soluble epoxide hydrolase: a target with multiple potential therapeutic indications
Shen_2012_J.Mol.Neurosci_48_14Functional alpha7 nicotinic ACh receptors on astrocytes in rat hippocampal CA1 slices
Shen_2012_Neurology_79_449Highly fatal fast-channel syndrome caused by AChR epsilon subunit mutation at the agonist binding site
Shen_2012_Pest.Manag.Sci_68_1553Biochemical and molecular characterisation of acetylcholinesterase in four field populations of Bactrocera dorsalis (Hendel) (Diptera: Tephritidae)
Shepard_2012_J.Bacteriol_194_395Genome sequences and phylogenetic analysis of K88- and F18-positive porcine enterotoxigenic Escherichia coli
Shi_2012_Arch.Pharm.Res_35_1645A novel 7-O-modified genistein derivative with acetylcholinesterase inhibitory effect, estrogenic activity and neuroprotective effect
Shi_2012_In.Vitro.Cell.Dev.Biol.Anim_48_603Lhx8 promote differentiation of hippocampal neural stem/progenitor cells into cholinergic neurons in vitro
Shi_2012_PLoS.ONE_7_E30828The immunomodulation of acetylcholinesterase in zhikong scallop Chlamys farreri
Shi_2012_Stem.Cells.Transl.Med_1_725Human Mesenchymal Stem Cell Transfusion Is Safe and Improves Liver Function in Acute-on-Chronic Liver Failure Patients
Shigeta_2012_Circulation_126_1838Dipeptidyl peptidase-4 modulates left ventricular dysfunction in chronic heart failure via angiogenesis-dependent and -independent actions
Shiina_2012_J.Org.Chem_77_4885MNBA-mediated beta-lactone formation: mechanistic studies and application for the asymmetric total synthesis of tetrahydrolipstatin
Shimazaki_2012_Clin.Chim.Acta_413_269Analysis of activity of esterase captured onto an immunoaffinity membrane
Shimizu-Fujiwara_2012_Brain.Dev_34_206Decreased resting energy expenditure in patients with Duchenne muscular dystrophy
Shimizu_2012_Drug.Metab.Dispos_40_1183A novel polymorphic allele of human arylacetamide deacetylase leads to decreased enzyme activity
Shimizu_2012_Eur.J.Pharmacol_691_93Brain phospholipase C, diacylglycerol lipase and monoacylglycerol lipase are involved in (+/-)-epibatidine-induced activation of central adrenomedullary outflow in rats
Shimomura_2012_J.Dermatol_39_3Congenital hair loss disorders: rare, but not too rare
Shin_2012_J.Bacteriol_194_2373Complete genome sequence of Enterobacter aerogenes KCTC 2190
Shin_2012_J.Bacteriol_194_2736Complete genome sequence of the 2,3-butanediol-producing Klebsiella pneumoniae strain KCTC 2242
Shin_2012_J.Bacteriol_194_4438Complete genome sequence of the opportunistic food-borne pathogen Cronobacter sakazakii ES15
Shinada_2012_Bioorg.Med.Chem_20_4901Synthesis of phenserine analogues and evaluation of their cholinesterase inhibitory activities
Shinkuma_2012_J.Invest.Dermatol_132_2093The beta9 loop domain of PA-PLA1alpha has a crucial role in autosomal recessive woolly hair/hypotrichosis
Shipman_2012_Neuron_76_309A subtype-specific function for the extracellular domain of neuroligin 1 in hippocampal LTP
Shipman_2012_Proc.Natl.Acad.Sci.U.S.A_109_19432Dimerization of postsynaptic neuroligin drives synaptic assembly via transsynaptic clustering of neurexin
Shirazi_2012_Int.J.Biol.Macromol_54C_180Structure-function analysis of a new bacterial lipase: Effect of local structure reorganization on lipase activity
Shishido_2012_Brain.Nerve_64_65[Autism spectrum disorder and genes for synaptic proteins]
Shivaji_2012_J.Bacteriol_194_6624Draft genome sequence of Bacillus isronensis strain B3W22, isolated from the upper atmosphere
Shivaji_2012_J.Bacteriol_194_6631Draft genome sequence of Cecembia lonarensis strain LW9T, isolated from Lonar Lake, a haloalkaline lake in India
Shivnaraine_2012_Biochemistry_51_4518Heterotropic cooperativity within and between protomers of an oligomeric M(2) muscarinic receptor
Shreder_2012_Bioorg.Med.Chem.Lett_22_5748Synthesis and structure-activity relationship of (1-halo-2-naphthyl) carbamate-based inhibitors of KIAA1363 (NCEH1/AADACL1)
Shrestha_2012_J.Invertebr.Pathol_109_91Oral toxicity of Photorhabdus culture media on gene expression of the adult sweetpotato whitefly, Bemisia tabaci
Shu_2012_Neurosci.Lett_512_103Effect of bis(7)-tacrine on cognition in rats with chronic cerebral ischemia
Shyma_2012_Exp.Appl.Acarol_58_471Acaricide resistance status in Indian isolates of Hyalomma anatolicum
Sidique_2012_J.Med.Chem_55_9434Orally active metabotropic glutamate subtype 2 receptor positive allosteric modulators: structure-activity relationships and assessment in a rat model of nicotine dependence
Silva_2012_Food.Chem.Toxicol_53C_240Chemical assessment and antioxidant capacity of pepper (Capsicum annuum L.) seeds
Silva_2012_Genet.Mol.Biol_35_741Effects of physical exercise on butyrylcholinesterase in obese adolescents
Silva_2012_J.Bacteriol_194_6663Complete genome sequence of Corynebacterium pseudotuberculosis Cp31, isolated from an Egyptian buffalo
Silva_2012_J.Biotechnol_161_228Molecular recognition of esterase plays a major role on the removal of fatty soils during detergency
Silva_2012_PLoS.One_7_e36366Insecticide resistance mechanisms in the green peach aphid Myzus persicae (Hemiptera: Aphididae) I: A transcriptomic survey
Silveira_2012_J.Phys.Chem.B_116_5671Enzyme microheterogeneous hydration and stabilization in supercritical carbon dioxide
Silvestri_2012_Semin.Neurol_32_215Myasthenia gravis
Silveyra_2012_Neurobiol.Aging_33_624 e23Altered expression of brain acetylcholinesterase in FTDP-17 human tau transgenic mice
Silveyra_2012_Neurobiol.Aging_33_627 e27Changes in acetylcholinesterase expression are associated with altered presenilin-1 levels
Simkhada_2012_Bioprocess.Biosyst.Eng_35_217A novel cold-adapted lipase, LP28, from a mesophilic Streptomyces strain
Simon_2012_Mol.Pharmacol_82_17Influence of the accessory protein SET on M3 muscarinic receptor phosphorylation and G protein coupling
Simoni_2012_J.Med.Chem_55_9708Combining galantamine and memantine in multitargeted, new chemical entities potentially useful in Alzheimer's disease
Simpson_2012_Apoptosis_17_666A genome wide shRNA screen identifies alpha/beta hydrolase domain containing 4 (ABHD4) as a novel regulator of anoikis resistance
Sine_2012_Physiol.Rev_92_1189End-plate acetylcholine receptor: structure, mechanism, pharmacology, and disease
Singh_2012_Appl.Biochem.Biotechnol_166_486Overview of fungal lipase: a review
Singh_2012_Appl.Biochem.Biotechnol_168_991Acetylcholinesterase Inhibitory Potential and Insecticidal Activity of an Endophytic Alternaria sp. from Ricinus communis
Singh_2012_Cochrane.Database.Syst.Rev_1_CD007967Acetylcholinesterase inhibitors for schizophrenia
Singh_2012_J.Bacteriol_194_6307Genome sequence of Nitratireductor aquibiodomus strain RA22
Singh_2012_Mutat.Res_741_101Influence of CYP2C9, GSTM1, GSTT1 and NAT2 genetic polymorphisms on DNA damage in workers occupationally exposed to organophosphate pesticides
Singh_2012_Nucleosides.Nucleotides.Nucleic.Acids_31_831Selective biocatalytic acylation studies on 5'-O-(4,4'-dimethoxytrityl)-2',3'-secouridine: an efficient synthesis of UNA monomer
Singhal_2012_Mol.Cell.Neurosci_51_112Distinct contributions of Galgt1 and Galgt2 to carbohydrate expression and function at the mouse neuromuscular junction
Sinha_2012_PLoS.One_7_e40188Energetics of Ortho-7 (oxime drug) translocation through the active-site gorge of tabun conjugated acetylcholinesterase
Sirota-Madi_2012_J.Bacteriol_194_2127Genome sequence of the pattern-forming social bacterium Paenibacillus dendritiformis C454 chiral morphotype
Skandalis_2012_J.Eur.Acad.Dermatol.Venereol_26_249Drug-induced bullous pemphigoid in diabetes mellitus patients receiving dipeptidyl peptidase-IV inhibitors plus metformin
Skinner-Adams_2012_Antimicrob.Agents.Chemother_56_3244The aminopeptidase inhibitor CHR-2863 is an orally bioavailable inhibitor of murine malaria
Slater_2012_Brain_135_997Diverse aspects of vulnerability at the neuromuscular junction
Slimani_2012_Am.J.Physiol.Endocrinol.Metab_303_E1335The worsening of tibialis anterior muscle atrophy during recovery post-immobilization correlates with enhanced connective tissue area, proteolysis, and apoptosis
Sloane_2012_PLoS.One_7_e39809A pharmacologic approach to acquired cystic fibrosis transmembrane conductance regulator dysfunction in smoking related lung disease
Slotkin_2012_Neurotoxicol.Teratol_34_232Developmental neurotoxicity of organophosphates targets cell cycle and apoptosis, revealed by transcriptional profiles in vivo and in vitro
Sluder_2012_PLoS.One_7_e34712Spiroindolines identify the vesicular acetylcholine transporter as a novel target for insecticide action
Small_2012_J.Neurochem_121_695Targeting pre-mRNA splicing: a BACE-ic strategy for AD drug development?
Small_2012_Neurodegener.Dis_10_76Dysregulation of Ca2+ homeostasis in Alzheimer's disease: role in acetylcholinesterase production and AMPA receptor internalization
Smith_2012_Curr.Biol_22_R924Strigolactones: destruction-dependent perception?
Smith_2012_J.Mol.Neurosci_48_403Is PACAP the major neurotransmitter for stress transduction at the adrenomedullary synapse?
Smith_2012_Toxicol.Sci_130_245Pharmacokinetics and Pharmacodynamics of Chlorpyrifos and 3,5,6-Trichloro-2-pyridinol in Rat Saliva After Chlorpyrifos Administration
Smyk_2012_Clin.Rev.Allergy.Immunol_42_199Autoimmunity and environment: am I at risk?
Snitkin_2012_Sci.Transl.Med_4_148RA116Tracking a hospital outbreak of carbapenem-resistant Klebsiella pneumoniae with whole-genome sequencing
Snyder_2012_Angew.Chem.Int.Ed.Engl_51_4080Total syntheses of hopeanol and hopeahainol A empowered by a chiral Bronsted acid induced pinacol rearrangement
Sofuoglu_2012_Psychopharmacology.(Berl)_224_413Galantamine attenuates some of the subjective effects of intravenous nicotine and improves performance on a Go No-Go task in abstinent cigarette smokers: a preliminary report
Sole_2012_Ecotoxicol.Environ.Saf_78_72Characterization of type B esterases and hepatic CYP450 isoenzimes in Senegalese sole for their further application in monitoring studies
Solomon_2012_Curr.Alzheimer.Res_9_1126Practical lessons from amyloid immunotherapy trials in Alzheimer disease
Somji_2012_Bioelectrochemistry_88_110Electroanalysis of amino acid substitutions in bioengineered acetylcholinesterase
Son_2012_Appl.Environ.Microbiol_78_8454Lipase and Protease Double-Deletion Mutant of Pseudomonas fluorescens Suitable for Extracellular Protein Production
Sona_2012_Int.Psychogeriatr_24_197Predictors of rapid cognitive decline in Alzheimer's disease: results from the Australian imaging, biomarkers and lifestyle (AIBL) study of ageing
Song_2012_Appl.Biochem.Biotechnol_168_364Lipase-catalyzed preparation of diacylglycerol-enriched oil from high-acid rice bran oil in solvent-free system
Song_2012_Chem.Biol.Interact_200_114Calcium-dependent neutral cysteine protease and organophosphate-induced delayed neuropathy
Song_2012_J.Bacteriol_194_3760Genome sequence of the plant growth-promoting rhizobacterium Bacillus sp. strain JS
Song_2012_J.Neurosci_32_5097Gating the polarity of endocannabinoid-mediated synaptic plasticity by nitric oxide in the spinal locomotor network
Song_2012_Langmuir_28_6157Enhanced catalytic activity of lipase encapsulated in PCL nanofibers
Song_2012_Pharmacogenomics.J_12_425Sequencing of Lp-PLA2-encoding PLA2G7 gene in 2000 Europeans reveals several rare loss-of-function mutations
Song_2012_Xenobiotica_42_231Stereoselective metabolism of (+/-)-praeruptorin A, a calcium channel blocker from Peucedani Radix, in pooled liver microsomes of rats and humans
Sonker_2012_Cent.Nerv.Syst.Agents.Med.Chem_12_28Conformationally controlled mechanistic aspects of BACE 1 inhibitors
Sorensen_2012_Environ.Microbiol_14_1159Production of novel fusarielins by ectopic activation of the polyketide synthase 9 cluster in Fusarium graminearum
Soreq_2012_Neurobiol.Dis_45_1018Meta-analysis of genetic and environmental Parkinson's disease models reveals a common role of mitochondrial protection pathways
Sorour_2012_J.Biotechnol_158_128Lipase-catalyzed synthesis of structured phenolic lipids in solvent-free system using flaxseed oil and selected phenolic acids as substrates
Sorrenti_2012_J.Pharm.Biomed.Anal_63_53Solid-state characterization of tacrine hydrochloride
Soudani_2012_J.Physiol.Biochem_68_397Ameliorating effect of selenium on chromium (VI)-induced oxidative damage in the brain of adult rats
Soukup_2012_Toxicol.Lett_212_315The interaction of standard oxime reactivators with hemicholinium-3 sensitive choline carriers
Souza_2012_PLoS.One_7_e32046Rapid enzymatic response to compensate UV radiation in copepods
Sozio_2012_Neuropsychiatr.Dis.Treat_8_361Transdermal donepezil on the treatment of Alzheimer's disease
Spalletta_2012_Psychiatry.Res_198_263The role of persistent and incident major depression on rate of cognitive deterioration in newly diagnosed Alzheimer's disease patients
Spang_2012_Environ.Microbiol_14_3122The genome of the ammonia-oxidizing Candidatus Nitrososphaera gargensis: insights into metabolic versatility and environmental adaptations
Speck-Planche_2012_Mini.Rev.Med.Chem_12_583Discovery of anti-Alzheimer agents: current ligand-based approaches toward the design of acetylcholinesterase inhibitors
Speed_2012_Toxicol.Sci_125_196Delayed reduction of hippocampal synaptic transmission and spines following exposure to repeated subclinical doses of organophosphorus pesticide in adult mice
Sperling_2012_PLoS.One_7_e36683Mouse acetylcholinesterase enhances neurite outgrowth of rat R28 cells through interaction with laminin-1
Spindel_2012_Handb.Exp.Pharmacol_208_451Muscarinic receptor agonists and antagonists: effects on cancer
Sridhar_2012_Adv.Alzheimer.Dis_1_1Human butyrylcholinesterase knock-out equivalent: Potential to assess role in Alzheimer'ss disease
Srinivasan_2012_Int.J.Mol.Sci_13_10022Forster Resonance Energy Transfer (FRET) Correlates of Altered Subunit Stoichiometry in Cys-Loop Receptors, Exemplified by Nicotinic alpha4beta2
Srinivasan_2012_Mol.Pharmacol_81_759Pharmacological chaperoning of nicotinic acetylcholine receptors reduces the endoplasmic reticulum stress response
Sriraksa_2012_Evid.Based.Complement.Alternat.Med_2012_823206Cognitive-enhancing effect of quercetin in a rat model of Parkinson's disease induced by 6-hydroxydopamine
Srisawasdi_2012_J.Clin.Lab.Anal_26_420Porcine pancreas: a superior source of cholesterol esterase for total serum cholesterol assay by the enzymatic kinetic method
Srivastava_2012_Cell.Mol.Biol.(Noisy-le-grand)_58_160Acetylcholinesterase from human erythrocytes membrane: a screen for evaluating the activity of some traditional plant extracts
Srividhya_2012_Neurochem.Int_60_517Impact of epigallo catechin-3-gallate on acetylcholine-acetylcholine esterase cycle in aged rat brain
St John_2012_Genome.Biol_13_415Sequencing three crocodilian genomes to illuminate the evolution of archosaurs and amniotes
Staats_2012_Eukaryot.Cell_11_1413Genome update of Botrytis cinerea strains B05.10 and T4
Stahl_2012_J.Bacteriol_194_4131Complete genome sequences of probiotic strains Bifidobacterium animalis subsp. lactis B420 and Bi-07
Stanneck_2012_Parasit.Vectors_5_73The synergistic action of imidacloprid and flumethrin and their release kinetics from collars applied for ectoparasite control in dogs and cats
Steele_2012_Environ.Health.Perspect_120_112Complex factors in the etiology of Gulf War illness: wartime exposures and risk factors in veteran subgroups
Stefanovic_2012_Clin.Chem.Lab.Med_50_2019Association of the atherogenic index of plasma and oxidative stress status with weight gain during non-complicated pregnancy
Stefanovic_2012_Reprod.Toxicol_33_20Longitudinal changes in PON1 activities, PON1 phenotype distribution and oxidative status throughout normal pregnancy
Stefanowicz_2012_J.Pediatr.Hematol.Oncol_34_461Renal function and low-molecular-weight proteins (cystatin C, beta2-microglobulin, neutrophil gelatinase-associated lipocalin) in child and young adult cancer survivors
Stegger_2012_J.Bacteriol_194_1625Genome sequence of Staphylococcus aureus strain 11819-97, an ST80-IV European community-acquired methicillin-resistant isolate
Steinberg_2012_Mol.Autism_3_8Identification of rare X-linked neuroligin variants by massively parallel sequencing in males with autism spectrum disorder
Steinberg_2012_PLoS.One_7_e38181Cytoplasmic fungal lipases release fungicides from ultra-deformable vesicular drug carriers
Stellpflug_2012_West.J.Emerg.Med_13_77Massive atropine eye drop ingestion treated with high-dose physostigmine to avoid intubation
Stephens_2012_Psychiatr.Genet_22_1Multiple genes in the 15q13-q14 chromosomal region are associated with schizophrenia
Stephenson_2012_Drugs.Aging_29_213Cholinesterase inhibitors and adverse pulmonary events in older people with chronic obstructive pulmonary disease and concomitant dementia: a population-based, cohort study
Stewart_2012_Front.Physiol_3_95RGS Proteins in Heart: Brakes on the Vagus
Sticht_2012_Br.J.Pharmacol_165_2425Inhibition of monoacylglycerol lipase attenuates vomiting in Suncus murinus and 2-arachidonoyl glycerol attenuates nausea in rats
Stoker_2012_Behav.Genet_42_423Role of alpha7- and beta4-containing nicotinic acetylcholine receptors in the affective and somatic aspects of nicotine withdrawal: studies in knockout mice
Stoker_2012_Psychopharmacology.(Berl)_221_317Involvement of metabotropic glutamate receptor 5 in brain reward deficits associated with cocaine and nicotine withdrawal and somatic signs of nicotine withdrawal
Stokes_2012_Neuropharmacol_63_538Use of an alpha3beta4 nicotinic acetylcholine receptor subunit concatamer to characterize ganglionic receptor subtypes with specific subunit composition reveals species-specific pharmacologic properties
Stolte_2012_Chemosphere_89_1135Ionic liquids as lubricants or lubrication additives: An ecotoxicity and biodegradability assessment
Storz_2012_J.Am.Chem.Soc_134_16143Validation of PqsD as an anti-biofilm target in Pseudomonas aeruginosa by development of small-molecule inhibitors
Strabala_2012_J.Bacteriol_194_201Draft genome sequence of Novosphingobium nitrogenifigens Y88(T)
Strobel_2012_BMC.Genomics_13_465Complete genome sequence of Saccharothrix espanaensis DSM 44229(T) and comparison to the other completely sequenced Pseudonocardiaceae
Strochlic_2012_PLoS.One_7_e29976Wnt4 participates in the formation of vertebrate neuromuscular junction
Strouts_2012_Emerg.Infect.Dis_18_449Lineage-specific virulence determinants of Haemophilus influenzae biogroup aegyptius
Stryjer_2012_Clin.Neuropharmacol_35_161Rivastigmine treatment for the prevention of electroconvulsive therapy-induced memory deficits in patients with schizophrenia
Su_2012_Microb.Cell.Fact_11_8Extracellular overexpression of recombinant Thermobifida fusca cutinase by alpha-hemolysin secretion system in E. coli BL21(DE3)
Suarez-Lopez_2012_Environ.Res_114_53Lower acetylcholinesterase activity among children living with flower plantation workers
Suarez-Suarez_2012_J.Bacteriol_194_5464Draft genome sequence of Citreicella aestuarii strain 357, a member of the Roseobacter clade isolated without xenobiotic pressure from a petroleum-polluted beach
Subramani_2012_Protein.J_31_120Purification and characterization of carboxylesterase from the seeds of Jatropha curcas
Suckow_2012_J.Biol.Chem_287_19816Transcellular neuroligin-2 interactions enhance insulin secretion and are integral to pancreatic beta cell function
Suehiro_2012_Rinsho.Byori_60_976[Genetic and epigenetic changes in colorectal cancer and genetic testing for personalized medicine]
Sugaya_2012_Int.J.Urol_19_480Effect of distigmine combined with propiverine on bladder activity in rats with spinal cord injury
Sulaiman_2012_Appl.Environ.Microbiol_78_1556Isolation of a novel cutinase homolog with polyethylene terephthalate-degrading activity from leaf-branch compost by using a metagenomic approach
Sumith_2012_Environ.Toxicol.Chem_31_1501Seasonal exposure of fish to neurotoxic pesticides in an intensive agricultural catchment, Uma-oya, Sri Lanka: linking contamination and acetylcholinesterase inhibition
Sun_2012_Diab.Vasc.Dis.Res_9_301Dipeptidyl peptidase-IV is a potential molecular biomarker in diabetic kidney disease
Sun_2012_J.Biotechnol_164_340Solvent-free enzymatic transesterification of ethyl ferulate and monostearin: optimized by response surface methodology
Sundstrom_2012_Gen.Comp.Endocrinol_177_322Characterization of the neuropeptide Y system in the frog Silurana tropicalis (Pipidae): three peptides and six receptor subtypes
Sung_2012_J.Bacteriol_194_6353Genome sequence of the halotolerant Staphylococcus sp. strain OJ82, isolated from Korean traditional salt-fermented seafood
Sung_2012_Mol.Biol.Rep_39_9989Effects of neo-adjuvant chemotherapy for oesophago-gastric cancer on neuro-muscular gastric function
Suplatov_2012_Protein.Eng.Des.Sel_25_689Bioinformatic analysis of alpha/beta-hydrolase fold enzymes reveals subfamily-specific positions responsible for discrimination of amidase and lipase activities
Surendran_2012_J.Intern.Med_272_185Mutations in LPL, APOC2, APOA5, GPIHBP1 and LMF1 in patients with severe hypertriglyceridaemia
Surendran_2012_Parasit.Vectors_5_34Variations in susceptibility to common insecticides and resistance mechanisms among morphologically identified sibling species of the malaria vector Anopheles subpictus in Sri Lanka
Surin_2012_Bioorg.Khim_38_214[Effect of alpha-conotoxin MII and its N-terminal derivatives on Ca2+ and Na+ signals induced by nicotine in neuroblastoma cell line SH-SY5Y]
Surmeier_2012_Neuron_75_1A feud that wasn't: acetylcholine evokes dopamine release in the striatum
Sussman_2012_Ann.N.Y.Acad.Sci_1275_13Further developments with antisense treatment for myasthenia gravis
Sutton_2012_Bioorg.Med.Chem.Lett_22_1464Novel heterocyclic DPP-4 inhibitors for the treatment of type 2 diabetes.
Suzuki_2012_Appl.Environ.Microbiol_78_3941Iodide oxidation by a novel multicopper oxidase from the alphaproteobacterium strain Q-1
Suzuki_2012_BMC.Genomics_13_38Comparative genomic analysis of the genus Staphylococcus including Staphylococcus aureus and its newly described sister species Staphylococcus simiae
Suzuki_2012_BMC.Genomics_13_444Comparative genomics of the white-rot fungi, Phanerochaete carnosa and P. chrysosporium, to elucidate the genetic basis of the distinct wood types they colonize
Suzuki_2012_Neuron_76_410Activity-dependent proteolytic cleavage of neuroligin-1
Svobodova_2012_Gen.Physiol.Biophys_31_77Cytotoxicity and genotoxicity evaluation of antidote oxime HI-6 tested on eight cell lines of human and rodent origin
Syad_2012_Evid.Based.Complement.Alternat.Med_2012_497242Assessment of Anticholinesterase Activity of Gelidiella acerosa: Implications for Its Therapeutic Potential against Alzheimer's Disease
Syren_2012_Chembiochem_13_645Esterases with an introduced amidase-like hydrogen bond in the transition state have increased amidase specificity
Szawlowska_2012_Biochem.Biophys.Res.Commun_419_104TsPAP1 encodes a novel plant prolyl aminopeptidase whose expression is induced in response to suboptimal growth conditions
Szeltner_2012_Biochim.Biophys.Acta_1834_98The loops facing the active site of prolyl oligopeptidase are crucial components in substrate gating and specificity
Sztanek_2012_Kidney.Blood.Press.Res_36_310Effect of nutritional status on human paraoxonase-1 activity in patients with chronic kidney disease
Sztanek_2012_Nephrol.Dial.Transplant_27_2866Decreased paraoxonase 1 (PON1) lactonase activity in hemodialyzed and renal transplanted patients. A novel cardiovascular biomarker in end-stage renal disease
Szule_2012_PLoS.One_7_e33333Regulation of synaptic vesicle docking by different classes of macromolecules in active zone material
Szymanski_2012_Arzneimittelforschung_62_655Synthesis, biological activity and molecular modeling of 4-fluoro-N-[omega-(1,2,3,4-tetrahydroacridin-9-ylamino)-alkyl]-benzamide derivatives as cholinesterase inhibitors
Szymanski_2012_Int.J.Mol.Sci_13_100672,3-dihydro-1H-cyclopenta[b]quinoline derivatives as acetylcholinesterase inhibitors-synthesis, radiolabeling and biodistribution
Tachibana_2012_Nat.Genet_44_1051Plasmodium cynomolgi genome sequences provide insight into Plasmodium vivax and the monkey malaria clade
Tada_2012_Genes.Cells_17_778Neuronally expressed Ras-family GTPase Di-Ras modulates synaptic activity in Caenorhabditis elegans
Tae_2012_Chembiochem_13_538Identification of hydrophobic tags for the degradation of stabilized proteins
Tae_2012_J.Bacteriol_194_910Complete genome sequence of Brucella suis VBI22, isolated from bovine milk
Tahir_2012_Bull.Environ.Contam.Toxicol_89_1138Assessment of pesticide exposure in female population living in cotton growing areas of punjab, pakistan
Tahir_2012_Pharmacopsychiatry_45_163; author reply 164A review for usefulness of atypical antipsychotics and cholinesterase inhibitors in delirium
Tai_2012_Behav.Brain.Res_232_174Vestibular stimulation enhances hippocampal long-term potentiation via activation of cholinergic septohippocampal cells
Tai_2012_Hippocampus_22_914Activation of immobility-related hippocampal theta by cholinergic septohippocampal neurons during vestibular stimulation
Tajima_2012_Appl.Microbiol.Biotechnol_94_365In vitro synthesis of polyhydroxyalkanoate (PHA) incorporating lactate (LA) with a block sequence by using a newly engineered thermostable PHA synthase from Pseudomonas sp. SG4502 with acquired LA-polymerizing activity
Takahashi_2012_Microbiol.Immunol_56_295Production and properties of lipase of Aeromonas sobria
Takami_2012_PLoS.ONE_7_e30559A deeply branching thermophilic bacterium with an ancient acetyl-CoA pathway dominates a subsurface ecosystem
Takehara_2012_Biosci.Biotechnol.Biochem_76_1721A novel alkaline esterase from Sporosarcina sp. nov. strain eSP04 catalyzing the hydrolysis of a wide variety of aryl-carboxylic acid esters
Takeno_2012_J.Bacteriol_194_4767Complete genome sequence of Bacillus cereus NC7401, which produces high levels of the emetic toxin cereulide
Takuma_2012_Neurosci_207_261Combination of chronic stress and ovariectomy causes conditioned fear memory deficits and hippocampal cholinergic neuronal loss in mice
Takusagawa_2012_Xenobiotica_42_957Identification of human cytochrome P450 isoforms and esterases involved in the metabolism of mirabegron, a potent and selective beta(3)-adrenoceptor agonist
Talaie_2012_Daru_20_52Temperature changes among organophosphate poisoned patients, Tehran- Iran
Talevich_2012_Philos.Trans.R.Soc.Lond.B.Biol.Sci_367_2607An evolutionary perspective on the kinome of malaria parasites
Talpate_2012_Zhong.Xi.Yi.Jie.He.Xue.Bao_10_939Clitorea ternatea, a herb from Indian folklore, improves streptozotocin-induced diabetes and diabetes-induced cognitive decline in rats
Tamilarasan_2012_Cell.Death.Dis_3_e354Skeletal muscle damage and impaired regeneration due to LPL-mediated lipotoxicity
Tamimi_2012_J.Bone.Miner.Res_27_1518Acetylcholinesterase inhibitors and the risk of hip fracture in Alzheimer's disease patients: a case-control study
Tamir-Ariel_2012_Mol.Plant.Pathol_13_556A secreted lipolytic enzyme from Xanthomonas campestris pv. vesicatoria is expressed in planta and contributes to its virulence
Tan_2012_PLoS.ONE_7_E47174Sequencing and analysis of full-length cDNAs, 5'-ESTs and 3'-ESTs from a cartilaginous fish, the elephant shark (Callorhinchus milii)
Tanaka_2012_BMC.Genomics_13_352A complete mitochondrial genome sequence of Ogura-type male-sterile cytoplasm and its comparative analysis with that of normal cytoplasm in radish (Raphanus sativus L.)
Tanaka_2012_Cell.Rep_2_101Higher-order architecture of cell adhesion mediated by polymorphic synaptic adhesion molecules neurexin and neuroligin.
Tanaka_2012_Nutrition_28_418Pepsinogen I/II ratio is related to glucose, triacylglycerol, and uric acid levels
Tang_2012_Appl.Environ.Microbiol_78_2272Short-read sequencing for genomic analysis of the brown rot fungus Fibroporia radiculosa
Tang_2012_Arterioscler.Thromb.Vasc.Biol_32_2803Clinical and genetic association of serum paraoxonase and arylesterase activities with cardiovascular risk
Tang_2012_Bioorg.Med.Chem.Lett_22_2257Novel oxoisoaporphine-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation
Tang_2012_Crit.Rev.Eukaryot.Gene.Expr_22_179Novel Insights into Mycobacterium Antigen Ag85 Biology and Implications in Countermeasures for M. tuberculosis
Tang_2012_J.Bacteriol_194_3553Genome sequence of a novel nicotine-degrading strain, Pseudomonas geniculata N1
Tang_2012_J.Bacteriol_194_5699Complete genome sequence of Amycolatopsis mediterranei S699 based on de novo assembly via a combinatorial sequencing strategy
Tang_2012_J.Bacteriol_194_6683Draft genome sequence of Oceaniovalibus guishaninsula JLT2003T
Tang_2012_J.Food.Sci_77_C454Enzymatic interesterification of palm stearin with Cinnamomum camphora seed oil to produce zero-trans medium-chain triacylglycerols-enriched plastic fat
Tang_2012_PLoS.ONE_7_E52038Semi-automatic in silico gap closure enabled de novo assembly of two Dehalobacter genomes from metagenomic data
Tang_2012_Sci.Rep_2_377Genomic analysis of Pseudomonas putida: genes in a genome island are crucial for nicotine degradation
Tangsucharit_2012_Am.J.Physiol.Regul.Integr.Comp.Physiol_303_R1147Do cholinergic nerves innervating rat mesenteric arteries regulate vascular tone?
Tao_2012_Appl.Environ.Microbiol_78_6295Inactivation of chloramphenicol and florfenicol by a novel chloramphenicol hydrolase
Tardy_2012_Appl.Environ.Microbiol_78_4659Emergence of atypical Mycoplasma agalactiae strains harboring a new prophage and associated with an alpine wild ungulate mortality episode
Targovnik_2012_Mol.Cell.Endocrinol_348_313Two novel mutations in the thyroglobulin gene as cause of congenital hypothyroidism: identification a cryptic donor splice site in the exon 19
Tariq_2012_Sci.Rep_2_730A novel mutation in the Lipase H gene underlies autosomal recessive hypotrichosis and woolly hair
Tarkiainen_2012_Clin.Pharmacol.Ther_92_68Carboxylesterase 1 polymorphism impairs oseltamivir bioactivation in humans
Tavares_2012_Food.Chem_135_562The neuroprotective potential of phenolic-enriched fractions from four Juniperus species found in Portugal
Tavares_2012_J.Am.Chem.Soc_134_11474Variations in binding among several agonists at two stoichiometries of the neuronal, alpha4beta2 nicotinic receptor
Tavares_2012_Pharm.Biol_50_239Bioactive compounds from endemic plants of Southwest Portugal: inhibition of acetylcholinesterase and radical scavenging activities
Tayeb_2012_Pharmacol.Ther_134_8Pharmacotherapies for Alzheimer's disease: beyond cholinesterase inhibitors
Tayebati_2012_J.Neurol.Sci_322_241Spontaneously hypertensive rat as a model of vascular brain disorder: microanatomy, neurochemistry and behavior
Tekedar_2012_J.Bacteriol_194_2763Genome sequence of the fish pathogen Flavobacterium columnare ATCC 49512
Temeyer_2012_J.Med.Entomol_49_555Sequence polymorphism in acetylcholinesterase transcripts and genotyping survey of BmAchE1 in laboratory and Mexican strains of Rhipicephalus (Boophilus) microplus
Temeyer_2012_J.Med.Entomol_49_589Acetylcholinesterase of Haematobia irritans (Diptera: Muscidae): baculovirus expression, biochemical properties, and organophosphate insensitivity of the G262A mutant
Temeyer_2012_Vet.Parasitol_184_92Acetylcholinesterase of Stomoxys calcitrans (L.) (Diptera: Muscidae): cDNA sequence, baculovirus expression, and biochemical properties
Teng_2012_J.Phys.Chem.B_116_11180Three-dimensional ordered macroporous (3DOM) composite for electrochemical study on acetylcholinesterase inhibition induced by endogenous neurotoxin
Teoh_2012_Cochrane.Database.Syst.Rev__CD003797Anticholinergic therapy for acute asthma in children
Teply_2012_Integr.Environ.Assess.Manag_8_271A spatially and temporally explicit model for determining the exposure of juvenile salmon to agricultural pesticides in freshwater
Terry_2012_Neurotoxicol.Teratol_34_1Chronic impairments in spatial learning and memory in rats previously exposed to chlorpyrfos or diisopropylfluorophosphate
Terry_2012_Pharmacol.Ther_134_355Functional consequences of repeated organophosphate exposure: potential non-cholinergic mechanisms
Testa-Silva_2012_Cereb.Cortex_22_1333Hyperconnectivity and slow synapses during early development of medial prefrontal cortex in a mouse model for mental retardation and autism
Tettelin_2012_J.Bacteriol_194_5450Genomic insights into the emerging human pathogen Mycobacterium massiliense
Thaipisuttikul_2012_Int.Psychogeriatr__1Capgras syndrome in Dementia with Lewy Bodies
Thangaraj_2012_J.Comp.Neurol_520_3181Intricate paths of cells and networks becoming Cholinergic in the embryonic chicken retina
Thatcher_2012_Mol.Plant.Microbe.Interact_25_180A highly conserved effector in Fusarium oxysporum is required for full virulence on Arabidopsis
Thierbach_2012_Chembiochem_13_1125Hydrolase-like properties of a cofactor-independent dioxygenase
Thole_2012_ISME.J_6_2229Phaeobacter gallaeciensis genomes from globally opposite locations reveal high similarity of adaptation to surface life
Thompson_2012_Methods.Mol.Biol_861_149High-throughput assay of secreted phospholipases A(2) inhibitors
Thompson_2012_Neuropharmacol_63_761The pharmacological profile of ELIC, a prokaryotic GABA-gated receptor
Thomsen_2012_Curr.Drug.Targets_13_707The alpha7 nicotinic acetylcholine receptor complex: one, two or multiple drug targets?
Thomsen_2012_J.Neuroimmunol_251_65The alpha7 nicotinic acetylcholine receptor ligands methyllycaconitine, NS6740 and GTS-21 reduce lipopolysaccharide-induced TNF-alpha release from microglia
Threlfell_2012_Neuron_75_58Striatal dopamine release is triggered by synchronized activity in cholinergic interneurons
Thumarat_2012_Appl.Microbiol.Biotechnol_95_419Biochemical and genetic analysis of a cutinase-type polyesterase from a thermophilic Thermobifida alba AHK119
Tiago_2012_J.Bacteriol_194_7010Genome sequence of Mycobacterium hassiacum DSM 44199, a rare source of heat-stable mycobacterial proteins
Tiegang_2012_Toxicol.Lett_210_366Polyethylene glycosylation prolongs the stability of recombinant human paraoxonase-1
Tietjen_2012_PLoS.One_7_e37437Segregation of LIPG, CETP, and GALNT2 mutations in Caucasian families with extremely high HDL cholesterol
Tifratene_2012_Pharmacoepidemiol.Drug.Saf_21_1005Use of drug treatments for Alzheimer's disease in France: a study on a national level based on the National Alzheimer's Data Bank (Banque Nationale Alzheimer)
Timme_2012_J.Bacteriol_194_5994Draft genome sequences of 21 Salmonella enterica serovar enteritidis strains
Timmermann_2012_Br.J.Pharmacol_167_164Augmentation of cognitive function by NS9283, a stoichiometry-dependent positive allosteric modulator of alpha2- and alpha4-containing nicotinic acetylcholine receptors
Tirello_2012_Exp.Appl.Acarol_56_1Resistance to chlorpyriphos in the predatory mite Kampimodromus aberrans
Tiwari_2012_J.Econ.Entomol_105_540Biochemical basis of organophosphate and carbamate resistance in Asian citrus psyllid
Tiwari_2012_Neurochem.Int_61_310Attenuation of NF-kappabeta mediated apoptotic signaling by tocotrienol ameliorates cognitive deficits in rats postnatally exposed to ethanol
Tiwari_2012_Psychopharmacology.(Berl)_224_519Attenuation of oxidative stress, neuroinflammation, and apoptosis by curcumin prevents cognitive deficits in rats postnatally exposed to ethanol
Tiwari_2012_ScientificWorldJournal_2012_291395Impact of cypermethrin on fingerlings of common edible carp (Labeo rohita)
Tobey_2012_Psychopharmacology.(Berl)_223_159Effects of the specific alpha4beta2 nAChR antagonist, 2-fluoro-3-(4-nitrophenyl) deschloroepibatidine, on nicotine reward-related behaviors in rats and mice
Tochitsky_2012_Nat.Chem_4_105Optochemical control of genetically engineered neuronal nicotinic acetylcholine receptors
Toda_2012_J.Alzheimers.Dis_32_569Cerebral blood flow regulation by nitric oxide in Alzheimer's disease
Todd_2012_J.Neurosci_32_11201Psychophysical and neural evidence for emotion-enhanced perceptual vividness
Toh_2012_Plant.Cell.Physiol_53_107Thermoinhibition uncovers a role for strigolactones in Arabidopsis seed germination
Tomasek_2012_Klin.Onkol_25_427[Liver function assessment in oncology practice]
Tomassoni_2012_Curr.Alzheimer.Res_9_120Effects of cholinergic enhancing drugs on cholinergic transporters in the brain and peripheral blood lymphocytes of spontaneously hypertensive rats
Tompkins_2012_J.Bacteriol_194_6349Complete genome sequence of Lactobacillus helveticus R0052, a commercial probiotic strain
Tompkins_2012_J.Bacteriol_194_902Draft genome sequence of probiotic strain Lactobacillus rhamnosus R0011
Tong_2012_Sheng.Wu.Gong.Cheng.Xue.Bao_28_1414[Progress in the structure and function of human carboxylesterase 1]
Topakas_2012_Appl.Microbiol.Biotechnol_94_399Expression, characterization and structural modelling of a feruloyl esterase from the thermophilic fungus Myceliophthora thermophila
Torre_2012_Molecules_17_12072A Novel Class of Selective Acetylcholinesterase Inhibitors: Synthesis and Evaluation of (E)-2-(Benzo[d]thiazol-2-yl)-3-heteroarylacrylonitriles
Torrent_2012_Commun.Integr.Biol_5_30High pressure, a tool to switch between soluble and fibrillar prion protein structures
Torres_2012_Methods.Mol.Biol_861_435Lipase-catalyzed modification of phenolic antioxidants
Torres_2012_Org.Biomol.Chem_10_3388Promiscuous enantioselective (-)-gamma-lactamase activity in the Pseudomonas fluorescens esterase I
Torres_2012_Phytochemistry_81_24Structural insights into cholinesterases inhibition by harmane beta-carbolinium derivatives: a kinetics-molecular modeling approach
Torzilli_2012_Ann.Surg_255_270Safety of intermittent Pringle maneuver cumulative time exceeding 120 minutes in liver resection: a further step in favor of the radical but conservative policy
Tosco_2012_J.Chem.Inf.Model_52_302A 3D-QSAR-driven approach to binding mode and affinity prediction
Tosolini_2012_Neurosci_200_19Spatial characterization of the motor neuron columns supplying the rat forelimb
Tota_2012_Behav.Brain.Res_226_317Central angiotensin converting enzyme facilitates memory impairment in intracerebroventricular streptozotocin treated rats
Tota_2012_Behav.Brain.Res_232_66Inhibition of central angiotensin converting enzyme ameliorates scopolamine induced memory impairment in mice: role of cholinergic neurotransmission, cerebral blood flow and brain energy metabolism
Tota_2012_Psychopharmacology.(Berl)_222_185Role of central angiotensin receptors in scopolamine-induced impairment in memory, cerebral blood flow, and cholinergic function
Toth_2012_Brain.Res.Bull_87_117Cholinergic modulation of slow cortical rhythm in urethane-anesthetized rats
Tran_2012_J.Biotechnol_158_112Immobilization of Burkholderia sp. lipase on a ferric silica nanocomposite for biodiesel production
Trapp_2012_J.Phys.Chem.B_116_14744Energy landscapes of human acetylcholinesterase and its huperzine a-inhibited counterpart
Trattnig_2012_J.Biol.Chem_287_25241Discovery of a novel allosteric modulator of 5-HT3 receptors: inhibition and potentiation of Cys-loop receptor signaling through a conserved transmembrane intersubunit site
Trautmann_2012_DNA.Res_19_435Microevolution in cyanobacteria: re-sequencing a motile substrain of Synechocystis sp. PCC 6803
Trbusic_2012_J.Neurol_259_448Increased expression of endothelial lipase in symptomatic and unstable carotid plaques
Trebbastoni_2012_Clin.Neurophysiol_123_902Chronic treatment with rivastigmine in patients with Alzheimer's disease: a study on primary motor cortex excitability tested by 5 Hz-repetitive transcranial magnetic stimulation
Trekels_2012_Ecotoxicology_21_268Species-specific responsiveness of four enzymes to endosulfan and predation risk questions their usefulness as general biomarkers
Trekels_2012_Environ.Pollut_163_127Species-specific patterns of swimming escape performance and cholinesterase activity in a guild of aquatic insects exposed to endosulfan
Tribelli_2012_J.Bacteriol_194_2381Genome sequence of the polyhydroxybutyrate producer Pseudomonas extremaustralis, a highly stress-resistant Antarctic bacterium
Tricco_2012_Syst.Rev_1_31Efficacy of cognitive enhancers for Alzheimer's disease: protocol for a systematic review and network meta-analysis
Tricoire-Leignel_2012_Front.Physiol_3_58Pest insect olfaction in an insecticide-contaminated environment: info-disruption or hormesis effect
Trimble_2012_J.Bacteriol_194_6355Draft genome sequence of Achromobacter piechaudii strain HLE
Trimble_2012_J.Bacteriol_194_6986Draft genome sequence of Agrobacterium albertimagni strain AOL15
Trinh_2012_J.Nat.Prod_75_2012Acetylcholinesterase Inhibitors from the Leaves of Macaranga kurzii
Triquigneaux_2012_Biochem.J_448_83Targeted oxidation of Torpedo californica acetylcholinesterase by singlet oxygen: identification of N-formylkynurenine tryptophan derivatives within the active-site gorge of its complex with the photosensitizer Methylene Blue
Triscari-Barberi_2012_J.Bacteriol_194_4426Genome sequence of the polychlorinated-biphenyl degrader Pseudomonas pseudoalcaligenes KF707
Trivedi_2012_Clin.Biochem_45_178Pitfalls in the determination of human acylated ghrelin plasma concentrations using a double antibody enzyme immunometric assay
Troeschel_2012_J.Biotechnol_161_71Novel broad host range shuttle vectors for expression in Escherichia coli, Bacillus subtilis and Pseudomonas putida
Tronson_2012_Trends.Neurosci_35_145Fear conditioning and extinction: emotional states encoded by distinct signaling pathways
Trost_2012_J.Bacteriol_194_3199Pangenomic study of Corynebacterium diphtheriae that provides insights into the genomic diversity of pathogenic isolates from cases of classical diphtheria, endocarditis, and pneumonia
Troudi_2012_Exp.Toxicol.Pathol_64_583Neurotoxicity and oxidative stress induced by gibberellic acid in rats during late pregnancy and early postnatal periods: biochemical and histological changes
Troudi_2012_Toxicol.Ind.Health_28_820Oxidative damage in erythrocytes of adult rats and their suckling pups exposed to gibberellic acid
Tsai_2012_Biochemistry_51_6463Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents
Tsai_2012_Plant.Biotechnol.J_10_1077Constitutive expression of a fungal glucuronoyl esterase in Arabidopsis reveals altered cell wall composition and structure
Tsarpali_2012_Aquat.Toxicol_124-125_58Investigation of landfill leachate toxic potency: an integrated approach with the use of stress indices in tissues of mussels
Tsim_2012_Front.Mol.Neurosci_5_101Acetylcholinesterase: old questions and new developments
Tsioupi_2012_Electrophoresis_33_516Chiral separation of Huperzine A using CE - method validation and application in pharmaceutical formulations
Tsuruoka_2012_PLoS.One_7_e50824A DKP Cyclo(L-Phe-L-Phe) Found in Chicken Essence Is a Dual Inhibitor of the Serotonin Transporter and Acetylcholinesterase
Tu_2012_Bioorg.Med.Chem_20_4422Synthesis and evaluation of in vitro bioactivity for vesicular acetylcholine transporter inhibitors containing two carbonyl groups
Tu_2012_Chemosphere_86_83Combined effects of deltamethrin, temperature and salinity on oxidative stress biomarkers and acetylcholinesterase activity in the black tiger shrimp (Penaeus monodon)
Tumen_2012_Int.J.Food.Sci.Nutr_63_387Inhibitory potential of the leaves and berries of Myrtus communis L. (myrtle) against enzymes linked to neurodegenerative diseases and their antioxidant actions
Tumer_2012_Arch.Toxicol_86_431Association between polymorphisms of EPHX1 and XRCC1 genes and the risk of childhood acute lymphoblastic leukemia
Tundis_2012_J.Food.Sci_77_H40Comparative study on the antioxidant capacity and cholinesterase inhibitory activity of Citrus aurantifolia Swingle, C. aurantium L., and C. bergamia Risso and Poit. peel essential oils
Tundis_2012_Nat.Prod.Commun_7_1015Antioxidant and anti-cholinesterase activity of Globularia meridionalis extracts and isolated constituents
Turan_2012_J.Agric.Food.Chem_60_4402Production of human milk fat analogue containing docosahexaenoic and arachidonic acids
Turcanu_2012_Neurosci.Lett_516_212Nicotinic receptor partial agonists alter catecholamine homeostasis and response to nicotine in PC12 cells
Turner_2012_J.Ind.Microbiol.Biotechnol_39_629Optical mapping and sequencing of the Escherichia coli KO11 genome reveal extensive chromosomal rearrangements, and multiple tandem copies of the Zymomonas mobilis pdc and adhB genes
Tvarijonaviciute_2012_Domest.Anim.Endocrinol_42_129Effects of weight loss in obese cats on biochemical analytes related to inflammation and glucose homeostasis
Tvarijonaviciute_2012_Res.Vet.Sci_93_668Serum butyrylcholinesterase and paraoxonase 1 in a canine model of endotoxemia: effects of choline administration
Uchida_2012_Biol.Pharm.Bull_35_1831The cyanine Dye NK-4 improves scopolamine-induced memory impairments in mice
Udatha_2012_PLoS.One_7_e39473Common and distant structural characteristics of feruloyl esterase families from Aspergillus oryzae
Udayabanu_2012_Neurosci_202_434Free chelatable zinc modulates the cholinergic function during hypobaric hypoxia-induced neuronal damage: an in vivo study
Uesaka_2012_J.Neurosci_32_11657Organotypic coculture preparation for the study of developmental synapse elimination in mammalian brain
Uhlemann_2012_MBio_3_e00027Identification of a highly transmissible animal-independent Staphylococcus aureus ST398 clone with distinct genomic and cell adhesion properties
Unal_2012_Front.Behav.Neurosci_6_21Adult mouse basal forebrain harbors two distinct cholinergic populations defined by their electrophysiology
Unwin_2012_J.Mol.Biol_422_617Gating movement of acetylcholine receptor caught by plunge-freezing
Ureshino_2012_PLoS.One_7_e41312N-myc downstream regulated gene 1 (NDRG1) promotes metastasis of human scirrhous gastric cancer cells through epithelial mesenchymal transition
Utkin_2012_Dokl.Biochem.Biophys_442_33The new peptide from the Fea's viper Azemiops feae venom interacts with nicotinic acetylcholine receptors
Utkin_2012_J.Biol.Chem_287_27079Azemiopsin from Azemiops feae viper venom, a novel polypeptide ligand of nicotinic acetylcholine receptor
Utsintong_2012_J.Biomol.Screen_17_204Virtual screening against acetylcholine binding protein
Uwano_2012_J.Am.Geriatr.Soc_60_1979Rivastigmine dermal patch solves eating problems in an individual with advanced Alzheimer's disease
Valant_2012_Mol.Pharmacol_81_41Probe dependence in the allosteric modulation of a G protein-coupled receptor: implications for detection and validation of allosteric ligand effects
Valero_2012_Methods.Mol.Biol_861_161Heterologous expression systems for lipases: a review
Valiyaveettil_2012_Neurosci.Lett_506_141Regional specific alterations in brain acetylcholinesterase activity after repeated blast exposures in mice
Van Der Veken_2012_J.Med.Chem_55_9856P2-substituted N-acylprolylpyrrolidine inhibitors of prolyl oligopeptidase: biochemical evaluation, binding mode determination, and assessment in a cellular model of synucleinopathy
Van den Oever_2012_Adv.Exp.Med.Biol_970_469The synaptic pathology of drug addiction
Vandesquille_2012_J.Psychopharmacol_26_845Effects of positive modulators of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors in a benzodiazepine-induced deficit of spatial discrimination in mice
Vanini_2012_Sleep_35_1325GABA-to-ACh ratio in basal forebrain and cerebral cortex varies significantly during sleep
Vardakou_2012_Protein.Expr.Purif_81_69Expression of active recombinant human gastric lipase in Nicotiana benthamiana using the CPMV-HT transient expression system
Varela-Nallar_2012_Cytoskeleton.(Hoboken)_69_528Frizzled receptors in neurons: from growth cones to the synapse
Varela-Nallar_2012_Neurodegener.Dis_10_23Wnt-5a is a synaptogenic factor with neuroprotective properties against Abeta toxicity
Varga_2012_J.Bacteriol_194_6356Draft genome sequence determination for cystic fibrosis and chronic granulomatous disease Burkholderia multivorans isolates
Varga_2012_Kidney.Blood.Press.Res_35_265Low high-density lipoprotein cholesterol is not responsible for decreased paraoxonase activity in chronic renal failure
Velasco-Lozano_2012_Methods.Mol.Biol_861_227Lipases production by solid-state fermentation: the case of Rhizopus homothallicus in perlite
Velki_2012_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_156_104Species-specific differences in biomarker responses in two ecologically different earthworms exposed to the insecticide dimethoate
Vellas_2012_J.Nutr.Health.Aging_16_330Recruitment, retention and other methodological issues related to clinical trials for Alzheimer's disease
Venable_2012_Methods.Mol.Biol_861_139Lipase and phospholipase inhibitors: design and applications
Vera-Cabrera_2012_J.Bacteriol_194_2761Complete genome sequence of Nocardia brasiliensis HUJEG-1
Verbout_2012_Handb.Exp.Pharmacol_208_403Muscarinic receptor agonists and antagonists: effects on inflammation and immunity
Versijpt_2012_Acta.Neurol.Belg_112_141Pharmacoeconomics of Alzheimer's disease (AD) treatment with cholinesterase inhibitors
Verstappen_2012_Chem.Biol.Interact_197_93Interactions of organophosphates with keratins in the cornified epithelium of human skin
Vetchy_2012_Ceska.Slov.Farm_61_234[Methods of pharmaceutical technology in preparation of pellets for detection of acetylcholinesterase inhibitors]
Vezenkov_2012_Curr.Alzheimer.Res_9_600Galantamine-based hybrid molecules with acetylcholinesterase, butyrylcholinesterase and gamma-secretase inhibition activities
Viertler_2012_Bioorg.Med.Chem_20_628Activity based subcellular resolution imaging of lipases
Vigneault_2012_Eur.J.Pharmacol_681_68Galantamine (Reminyl) delays cardiac ventricular repolarization and prolongs the QT interval by blocking the HERG current
Vijayakumar_2012_Protein.Expr.Purif_88_67Rice (Oryza sativa) lipase: Molecular cloning, functional expression and substrate specificity
Vijayalakshmi_2012_Indian.J.Pharmacol_44_82Evaluation of the effect of Ferula asafoetida Linn. gum extract on learning and memory in Wistar rats
Vijayaraj_2012_Plant.Physiol_160_667A bifunctional enzyme that has both monoacylglycerol acyltransferase and acyl hydrolase activities
Vikram_2012_J.Bacteriol_194_3543Draft genome sequence of the nitrophenol-degrading actinomycete Rhodococcus imtechensis RKJ300
Villeneuve_2012_J.Bacteriol_194_4126Complete genome sequences of Methylophaga sp. strain JAM1 and Methylophaga sp. strain JAM7
Vilo_2012_J.Bacteriol_194_6618Draft genome sequence of the cyanide-utilizing bacterium Pseudomonas fluorescens strain NCIMB 11764
Vishwasrao_2012_Biophys.J_102_1204In vivo imaging of the actin polymerization state with two-photon fluorescence anisotropy
Vitorovic-Todorovic_2012_J.Mol.Graph.Model_38C_194The 3D-QSAR study of 110 diverse, dual binding, acetylcholinesterase inhibitors based on alignment independent descriptors (GRIND-2). The effects of conformation on predictive power and interpretability of the models
Vittos_2012_Biomarkers_17_289Lipoprotein-associated phospholipase A2 (Lp-PLA2): a review of its role and significance as a cardiovascular biomarker
Vlassenko_2012_Biochim.Biophys.Acta_1822_370PET amyloid-beta imaging in preclinical Alzheimer's disease
Vlcek_2012_Mil.Med.Sci.Lett_81_2Carbamate insecticides in the czech republic: health and environmental impacts
Vo_2012_Chem.Pharm.Bull.(Tokyo)_60_1125Lignans and triterpenes from the root of Pseuderanthemum carruthersii var. atropurpureum
Vogel-Hopker_2012_Protein.Pept.Lett_19_155Co-opting functions of cholinesterases in neural, limb and stem cell development
Vogel_2012_PLoS.One_7_e38969Short term evolution of a highly transmissible methicillin-resistant Staphylococcus aureus clone (ST228) in a tertiary care hospital
Voll_2012_Appl.Biochem.Biotechnol_168_1121Kinetic modeling of solvent-free lipase-catalyzed partial hydrolysis of palm oil
Vontas_2012_Pestic.Biochem.Physiol_104_126Insecticide resistance in the major dengue vectors Aedes albopictus and Aedes aegypti
Vorobiev_2012_Protein.Pept.Lett_19_194Human retinoblastoma binding protein 9, a serine hydrolase implicated in pancreatic cancers
Voros_2012_J.Bacteriol_194_1621Complete genome sequences of three Propionibacterium acnes isolates from the type IA(2) cluster
Vuaden_2012_Neurochem.Res_37_1545Long-term methionine exposure induces memory impairment on inhibitory avoidance task and alters acetylcholinesterase activity and expression in zebrafish (Danio rerio)
Vuilleumier_2012_J.Bacteriol_194_551Genome sequence of the haloalkaliphilic methanotrophic bacterium Methylomicrobium alcaliphilum 20Z
Wackler_2012_ChemBioChem_13_1798Characterization of the Suillus grevillei quinone synthetase GreA supports a nonribosomal code for aromatic alpha-keto acids
Wahab_2012_Appl.Biochem.Biotechnol_167_612Manipulation of the conformation and enzymatic properties of T1 lipase by site-directed mutagenesis of the protein core
Wahab_2012_Int.J.Mol.Sci_13_11666Combination of Oxyanion Gln114 Mutation and Medium Engineering to Influence the Enantioselectivity of Thermophilic Lipase from Geobacillus zalihae
Walker_2012_BMJ.Open_2_e000380Comparison of cognitive decline between dementia with Lewy bodies and Alzheimer's disease: a cohort study
Walker_2012_Chembiochem_13_1645Substrate-induced conformational change and isomerase activity of dienelactone hydrolase and its site-specific mutants
Wan_2012_Am.J.Respir.Crit.Care.Med_186_1248Systemic steroid exposure is associated with differential methylation in chronic obstructive pulmonary disease
Wang_2012_Acta.Biomater_8_589A smart micellar system with an amine-containing polycarbonate shell
Wang_2012_Am.J.Cardiol_110_1551Cardiovascular preventing effects of dipeptidyl peptidase-4 inhibitors: beyond glucagon-like Peptide-1
Wang_2012_Anal.Chem_84_9706Enzyme mimics of au/ag nanoparticles for fluorescent detection of acetylcholine
Wang_2012_Annu.Rev.Nutr_32_147Lipoprotein lipase in the brain and nervous system
Wang_2012_Appl.Biochem.Biotechnol_166_1355Constitutive expression of Yarrowia lipolytica lipase LIP2 in Pichia pastoris using GAP as promoter
Wang_2012_Appl.Environ.Microbiol_78_7985AidC, a novel N-acylhomoserine lactonase from the potato root-associated cytophaga-flavobacteria-bacteroides (CFB) group bacterium Chryseobacterium sp. strain StRB126
Wang_2012_Appl.Microbiol.Biotechnol_96_443Enhanced activity of Rhizomucor miehei lipase by directed evolution with simultaneous evolution of the propeptide
Wang_2012_BMC.Pharmacol_12_2Potency, selectivity and prolonged binding of saxagliptin to DPP4: maintenance of DPP4 inhibition by saxagliptin in vitro and ex vivo when compared to a rapidly-dissociating DPP4 inhibitor
Wang_2012_Beilstein.J.Nanotechnol_3_444Magnetic-Fe/Fe(3)O(4)-nanoparticle-bound SN38 as carboxylesterase-cleavable prodrug for the delivery to tumors within monocytes/macrophages
Wang_2012_Bioorg.Med.Chem_20_6513Novel multipotent phenylthiazole-tacrine hybrids for the inhibition of cholinesterase activity, beta-amyloid aggregation and Ca(2+) overload
Wang_2012_Biotechnol.Lett_34_145Genome shuffling improves production of the low-temperature alkalophilic lipase by Acinetobacter johnsonii
Wang_2012_Biotechnol.Lett_34_55Regioselectivity-reversal in acylation of 6-azauridine catalyzed by Burkholderia cepacia lipase
Wang_2012_Chem.Cent.J_6_96Synthesis and biological evaluation of lycorine derivatives as dual inhibitors of human acetylcholinesterase and butyrylcholinesterase
Wang_2012_Chin.J.Integr.Med_18_699Analysis on interrelation between electroacupuncture-induced cumulative analgesic effect and hypothalamic cholinergic activities in chronic neuropathic pain rats
Wang_2012_Comb.Chem.High.Throughput.Screen_15_492Classification of acetylcholinesterase inhibitors and decoys by a support vector machine
Wang_2012_Dev.Cell_23_1072Silencing of germline-expressed genes by DNA elimination in somatic cells
Wang_2012_Environ.Toxicol_27_50Responses of AChE and GST activities to insecticide coexposure in Carassius auratus
Wang_2012_Enzyme.Microb.Technol_51_107Two plate-based colorimetric assays for screening alpha-amino acid ester hydrolase with high synthesis/hydrolysis ratio
Wang_2012_Exp.Neurol_236_79Huperzine A ameliorates experimental autoimmune encephalomyelitis via the suppression of T cell-mediated neuronal inflammation in mice
Wang_2012_J.Asian.Nat.Prod.Res_14_1084Protection of salvianolic acid A on rat brain from ischemic damage via soluble epoxide hydrolase inhibition
Wang_2012_J.Bacteriol_194_3270Complete genome sequence of Riemerella anatipestifer reference strain
Wang_2012_J.Bacteriol_194_4144Draft genome sequence of Streptomyces globisporus C-1027, which produces an antitumor antibiotic consisting of a nine-membered enediyne with a chromoprotein
Wang_2012_J.Bacteriol_194_5467Genome sequence of the plant growth-promoting rhizobacterium Bacillus sp. strain 916
Wang_2012_J.Bacteriol_194_6348Draft genome sequence of Alicyclobacillus hesperidum strain URH17-3-68
Wang_2012_J.Bacteriol_194_899Genome sequence of deep-sea manganese-oxidizing bacterium Marinobacter manganoxydans MnI7-9
Wang_2012_J.Biol.Chem_287_21957Potential state-selective hydrogen bond formation can modulate activation and desensitization of the alpha7 nicotinic acetylcholine receptor
Wang_2012_J.Biol.Chem_287_6482Intramembrane proton binding site linked to activation of bacterial pentameric ion channel
Wang_2012_J.Ethnopharmacol_139_214Trillin, a steroidal saponin isolated from the rhizomes of Dioscorea nipponica, exerts protective effects against hyperlipidemia and oxidative stress
Wang_2012_J.Med.Chem_55_3588Multifunctional mercapto-tacrine derivatives for treatment of age-related neurodegenerative diseases
Wang_2012_J.Neurosci.Res_90_508Huperzine A alleviates synaptic deficits and modulates amyloidogenic and nonamyloidogenic pathways in APPswe/PS1dE9 transgenic mice
Wang_2012_Methods.Mol.Biol_861_123Plant phospholipases: an overview
Wang_2012_Mol.Microbiol_83_195The genetic and structural basis of two distinct terminal side branch residues in stewartan and amylovoran exopolysaccharides and their potential role in host adaptation
Wang_2012_Neurotoxicol_33_169Neuroprotective effects of imidazenil against chemical warfare nerve agent soman toxicity in guinea pigs
Wang_2012_Plant.J_72_461The genome of flax (Linum usitatissimum) assembled de novo from short shotgun sequence reads
Wang_2012_Reprod.Toxicol_34_489Evidence for diazinon-mediated inhibition of cis-permethrin metabolism and its effects on reproductive toxicity in adult male mice
Wang_2012_Ying.Yong.Sheng.Tai.Xue.Bao_23_1933[Resistance mechanisms and cross-resistance of phoxim-resistant Frankliniella occidentalis Pergande population]
Wang_2012_Zhongguo.Zhong.Yao.Za.Zhi_37_3701[Screening of endophytic fungi from Huperzia serrata for acetylcholinesterase inhibitory activity and its taxonomic identification]
Wargon_2012_Neuromuscul.Disord_22_318Long-term follow-up of patients with congenital myasthenic syndrome caused by COLQ mutations
Warner-Schmidt_2012_Proc.Natl.Acad.Sci.U.S.A_109_11360Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior
Warrier_2012_Antimicrob.Agents.Chemother_56_1735Antigen 85C inhibition restricts Mycobacterium tuberculosis growth through disruption of cord factor biosynthesis
Wasukira_2012_Genes.(Basel)_3_361Genome-wide sequencing reveals two major sub-lineages in the genetically monomorphic pathogen xanthomonas campestris pathovar musacearum
Watanabe_2012_Appl.Environ.Microbiol_78_6545Draft genome sequence of a psychrotolerant sulfur-oxidizing bacterium, Sulfuricella denitrificans skB26, and proteomic insights into cold adaptation
Watanabe_2012_J.Bacteriol_194_7007Complete sequence of the first chimera genome constructed by cloning the whole genome of Synechocystis strain PCC6803 into the Bacillus subtilis 168 genome
Waters_2012_Appl.Environ.Microbiol_78_3759Cloning, overexpression in Escherichia coli, and characterization of a thermostable fungal acetylxylan esterase from Talaromyces emersonii
Waters_2012_Development_139_1285Specialisation within the DWARF14 protein family confers distinct responses to karrikins and strigolactones in Arabidopsis.
Waters_2012_Ecol.Evol_2_211Chloroplast genome sequence confirms distinctness of Australian and Asian wild rice
Waters_2012_Plant.Physiol_159_1073The Arabidopsis ortholog of rice DWARF27 acts upstream of MAX1 in the control of plant development by strigolactones
Waters_2012_Plant.Signal.Behav_7_969Karrikins force a rethink of strigolactone mode of action
Wathen_2012_Sleep_35_315Olanzapine causes a leptin-dependent increase in acetylcholine release in mouse prefrontal cortex
Wattmo_2012_BMC.Neurol_12_134Functional response to cholinesterase inhibitor therapy in a naturalistic Alzheimer's disease cohort
Weaver_2012_Drug.Alcohol.Depend_125_307Adolescent exposure to nicotine results in reinforcement enhancement but does not affect adult responding in rats
Weaver_2012_Nicotine.Tob.Res_14_824Precipitated withdrawal from nicotine reduces reinforcing effects of a visual stimulus for rats
Wei_2012_Cancer.Biol.Ther_14_Oncogenic but non-essential role of N-myc downstream regulated gene 1 in the progression of esophageal squamous cell carcinoma
Wei_2012_J.Bacteriol_194_547Genome sequence of Mycoplasma iowae strain 695, an unusual pathogen causing deaths in turkeys
Weidner_2012_J.Bacteriol_194_1617Genome sequence of the soybean symbiont Sinorhizobium fredii HH103
Weinreb_2012_Curr.Drug.Targets_13_483Ladostigil: a novel multimodal neuroprotective drug with cholinesterase and brain-selective monoamine oxidase inhibitory activities for Alzheimer's disease treatment
Weinstein_2012_Arterioscler.Thromb.Vasc.Biol_32_230Reciprocal metabolic perturbations in the adipose tissue and liver of GPIHBP1-deficient mice
Weiss_2012_Appl.Environ.Microbiol_78_8254Two enzymes of a complete degradation pathway for linear alkylbenzenesulfonate (LAS) surfactants: 4-sulfoacetophenone Baeyer-Villiger monooxygenase and 4-sulfophenylacetate esterase in Comamonas testosteroni KF-1
Welberg_2012_Nat.Rev.Neurosci_13_603Synaptic physiology: Neuroligin and neurexin go retro
Welberg_2012_Nat.Rev.Neurosci_13_811Synaptic plasticity: Neuroligin 1 does the splits
Wen_2012_J.Biotechnol_164_248Improving the thermostability of lipase Lip2 from Yarrowia lipolytica
Wen_2012_Zhongguo.Zhong.Yao.Za.Zhi_37_2971[Research on quality standards of herbs of Peganum harmala]
Wess_2012_Handb.Exp.Pharmacol_208_95Novel muscarinic receptor mutant mouse models
Wessler_2012_Handb.Exp.Pharmacol_208_469Activation of muscarinic receptors by non-neuronal acetylcholine
Wessler_2012_Life.Sci_91_1119Blockade of nicotinic and muscarinic receptors facilitates spontaneous migration of human peripheral granulocytes: failure in cystic fibrosis
Wessler_2012_Life.Sci_91_973Release of acetylcholine from murine embryonic stem cells: effect of nicotinic and muscarinic receptors and blockade of organic cation transporter
Wessler_2012_Life.Sci_91_977Subcellular distribution of choline acetyltransferase by immunogold electron microscopy in non-neuronal cells: placenta, airways and murine embryonic stem cells
White_2012_Eur.J.Anaesthesiol_29_211; author reply 212Pseudocholinesterase deficiency in specific populations
White_2012_J.Neurophysiol_107_2672Acetylcholine-evoked afterdischarge in Aplysia bag cell neurons
Wibmer_2012_Invest.Radiol_47_353Liver transplantation: impaired biliary excretion of gadoxate is associated with an inferior 1-year retransplantation-free survival
Wiedner_2012_J.Biol.Chem_287_33447Multiplexed activity-based protein profiling of the human pathogen Aspergillus fumigatus reveals large functional changes upon exposure to human serum
Wilkinson_2012_Int.J.Geriatr.Psychiatry_27_769A review of the effects of memantine on clinical progression in Alzheimer's disease
Wilkinson_2012_J.Alzheimers.Dis_29_459Memantine and brain atrophy in Alzheimer's disease: a 1-year randomized controlled trial
Williams_2012_Mol.Pharmacol_82_746Intrinsically low open probability of alpha7 nicotinic acetylcholine receptors can be overcome by positive allosteric modulation and serum factors leading to the generation of excitotoxic currents at physiological temperatures
Wilson_2012_Int.J.Oncol_41_919Expression profiling of dipeptidyl peptidase 8 and 9 in breast and ovarian carcinoma cell lines
Wilson_2012_J.Biochem.Mol.Toxicol_26_506Carbamate Protection of AChE Against Inhibition by Agricultural Chemicals
Winzer_2012_Science_336_1704A Papaver somniferum 10-gene cluster for synthesis of the anticancer alkaloid noscapine
Wise_2012_ACS.Chem.Neurosci_3_369Dual fatty acid amide hydrolase and monoacylglycerol lipase blockade produces THC-like Morris water maze deficits in mice
Wiskerke_2012_ACS.Chem.Neurosci_3_407Characterization of the effects of reuptake and hydrolysis inhibition on interstitial endocannabinoid levels in the brain: an in vivo microdialysis study
Withers_2012_J.Bacteriol_194_6617Draft genome sequence for Pseudomonas aeruginosa strain PAO579, a mucoid derivative of PAO381
Witte_2012_J.Lipids_2012_342806Protectors or Traitors: The Roles of PON2 and PON3 in Atherosclerosis and Cancer
Wittel_2012_Int.J.Oncol_41_5The pathobiological impact of cigarette smoke on pancreatic cancer development (review)
Witteles_2012_J.Card.Fail_18_804Dipeptidyl peptidase 4 inhibition increases myocardial glucose uptake in nonischemic cardiomyopathy
Witzel_2012_J.Bacteriol_194_5469Genome sequence of Enterobacter radicincitans DSM16656(T), a plant growth-promoting endophyte
Wolf-Johnston_2012_Life.Sci_91_1065Alterations in the non-neuronal acetylcholine synthesis and release machinery in esophageal epithelium
Wolff_2012_Am.J.Geriatr.Pharmacother_10_219Case report: Post-traumatic memories triggered by donepezil in a dose-dependent pattern
Wolff_2012_Life.Sci_91_1003Cholinergic receptors in the murine oviduct: inventory and coupling to intracellular calcium concentration
Wolkart_2012_Br.J.Pharmacol_165_380Cardiac dysfunction in adipose triglyceride lipase deficiency: treatment with a PPARalpha agonist
Wolkmer_2012_Exp.Parasitol_132_546Biochemistry detection of acetylcholinesterase activity in Trypanosoma evansi and possible functional correlations
Wolkmer_2012_Parasitol.Int_62_144Pre-treatment with curcumin modulates acetylcholinesterase activity and proinflammatory cytokines in rats infected with Trypanosoma evansi
Wong_2012_Biotechnol.Res.Int_2012_951267Functional Cloning and Expression of the Schizophyllum commune Glucuronoyl Esterase Gene and Characterization of the Recombinant Enzyme
Wong_2012_J.Bacteriol_194_6326Genome sequence of Pseudomonas mendocina DLHK, isolated from a biotrickling reactor
Wong_2012_J.Pharmacol.Exp.Ther_340_422Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity
Wong_2012_Mini.Rev.Med.Chem_12_936QSAR applications during last decade on inhibitors of acetylcholinesterase in Alzheimer's disease
Wong_2012_Nat.Prod.Res_26_850A new sesquiterpenoid from the rhizomes of Homalomena sagittifolia
Wong_2012_PLoS.One_7_e46712Select small core structure carbamates exhibit high contact toxicity to carbamate-resistant strain malaria mosquitoes, Anopheles gambiae (Akron)
Wongtrakool_2012_Am.J.Respir.Cell.Mol.Biol_46_695Prenatal nicotine exposure alters lung function and airway geometry through alpha7 nicotinic receptors
Woo_2012_Int.J.Mol.Med_29_403Flavanones inhibit the clonogenicity of HCT116 cololectal cancer cells
Wood_2012_Biomol.NMR.Assign_6_15Backbone and side chain NMR assignments for the intrinsically disordered cytoplasmic domain of human neuroligin-3
Woodhams_2012_Br.J.Pharmacol_167_1609Spinal administration of the monoacylglycerol lipase inhibitor JZL184 produces robust inhibitory effects on nociceptive processing and the development of central sensitization in the rat
Wootten_2012_Mol.Pharmacol_82_281Allosteric modulation of endogenous metabolites as an avenue for drug discovery
Worek_2012_Arch.Toxicol_86_1379Reactivation kinetics of a homologous series of bispyridinium bis-oximes with nerve agent-inhibited human acetylcholinesterase
Worek_2012_Biochem.Pharmacol_83_1700Reactivation kinetics of a series of related bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase--Structure-activity relationships
Worek_2012_Drug.Test.Anal_4_282Determination of acetylcholinesterase activity by the Ellman assay: a versatile tool for in vitro research on medical countermeasures against organophosphate poisoning
Wortmann_2012_Nat.Genet_44_797Mutations in the phospholipid remodeling gene SERAC1 impair mitochondrial function and intracellular cholesterol trafficking and cause dystonia and deafness
Wrighton_2012_Science_337_1661Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated bacterial phyla
Wu_2012_Anal.Chem_84_10586Exploration of two-enzyme coupled catalysis system using scanning electrochemical microscopy
Wu_2012_Appl.Biochem.Biotechnol_168_129New feruloyl esterases to access phenolic acids from grass biomass
Wu_2012_Arch.Pharm.(Weinheim)_345_175Synthesis and acetylcholinesterase and butyrylcholinesterase inhibitory activities of 7-alkoxyl substituted indolizinoquinoline-5,12-dione derivatives
Wu_2012_BMC.Genomics_13_337Genomic and transcriptomic insights into the thermo-regulated biosynthesis of validamycin in Streptomyces hygroscopicus 5008
Wu_2012_Bioorg.Med.Chem.Lett_22_55364-Substituted boro-proline dipeptides: synthesis, characterization, and dipeptidyl peptidase IV, 8, and 9 activities
Wu_2012_Bull.Environ.Contam.Toxicol_89_664Residues and dissipation dynamics of fosthiazate in tomato and soil
Wu_2012_Chem.Biol.Drug.Des_79_897Synthesis, structure-activity relationship, and pharmacophore modeling studies of pyrazole-3-carbohydrazone derivatives as dipeptidyl peptidase IV inhibitors
Wu_2012_Clin.Toxicol.(Phila)_50_514Peripheral nerve and skin damage associated with working in a STCP factory: report of four cases
Wu_2012_Endocrinology_153_2198Fasting energy homeostasis in mice with adipose deficiency of desnutrin/adipose triglyceride lipase
Wu_2012_Eur.J.Pharm.Biopharm_80_368A novel small Odorranalectin-bearing cubosomes: preparation, brain delivery and pharmacodynamic study on amyloid-beta(2)(5)(-)(3)(5)-treated rats following intranasal administration
Wu_2012_J.Am.Chem.Soc_134_17342Insights into pyrroindomycin biosynthesis reveal a uniform paradigm for tetramate/tetronate formation
Wu_2012_Molecules_17_10108Ameliorative effects of curculigoside from Curculigo orchioides Gaertn on learning and memory in aged rats
Wu_2012_Neuron_75_94Distinct roles of muscle and motoneuron LRP4 in neuromuscular junction formation
Wu_2012_Ying.Yong.Sheng.Tai.Xue.Bao_23_1952[Effects of soybean trypsinase inhibitor and defense signaling compounds on detoxification enzymes in Spodoptera litura (F.) larvae]
Wu_2012_Zhonghua.Nei.Ke.Za.Zhi_51_524[The relationship between carboxylesterase 1 gene polymorphisms and susceptibility to antituberculosis drug-induced hepatotoxicity]
Wylie_2012_Neuroimage_63_73Nicotine increases brain functional network efficiency
Wynne_2012_Proteome.Sci_10_22Production and proteomic characterisation of purified protein derivative from Mycobacterium avium subsp. paratuberculosis
Xia_2012_Brain.Res_1441_27Memory defect induced by beta-amyloid plus glutamate receptor agonist is alleviated by catalpol and donepezil through different mechanisms
Xia_2012_J.Vet.Intern.Med_26_415Concentrations of plasma metabolites, hormones, and mRNA abundance of adipose leptin and hormone-sensitive lipase in ketotic and nonketotic dairy cows
Xian_2012_Evid.Based.Complement.Alternat.Med_2012_802625Bioassay-Guided Isolation of Neuroprotective Compounds from Uncaria rhynchophylla against Beta-Amyloid-Induced Neurotoxicity
Xiang_2012_J.Pharm.Pharmacol_64_589PPARgamma agonist pioglitazone improves scopolamine-induced memory impairment in mice
Xiang_2012_J.Pharmacol.Exp.Ther_340_595Roles of the M1 muscarinic acetylcholine receptor subtype in the regulation of basal ganglia function and implications for the treatment of Parkinson's disease
Xiao_2012_Cell.Mol.Neurobiol_32_399Correlations between cholinesterase activity and cognitive scores in post-ischemic rats and patients with vascular dementia
Xiao_2012_Sci.Rep_2_483Genomic perspectives on the evolution of fungal entomopathogenicity in Beauveria bassiana
Xie_2012_Eur.J.Med.Chem_52_205Novel pyrrolopyrimidine analogues as potent dipeptidyl peptidase IV inhibitors based on pharmacokinetic property-driven optimization
Xie_2012_J.Bacteriol_194_1637Genome sequence of the cycloprodigiosin-producing bacterial strain Pseudoalteromonas rubra ATCC 29570(T)
Xie_2012_J.Bacteriol_194_2746Genome sequences of type strains of seven species of the marine bacterium Pseudoalteromonas
Xie_2012_J.Microbiol.Biotechnol_22_84Characterization of lipases from Staphylococcus aureus and Staphylococcus epidermidis isolated from human facial sebaceous skin
Xie_2012_J.Pharmacol.Exp.Ther_341_43Salsolinol stimulates dopamine neurons in slices of posterior ventral tegmental area indirectly by activating mu-opioid receptors
Xin_2012_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_899_127Direct pharmacokinetic analysis of puqietinone by in vivo microdialysis sampling and turbulent-flow chromatography coupled with liquid chromatography-mass spectrometry
Xing_2012_Langmuir_28_6032Acetylcholinesterase responsive polymeric supra-amphiphiles for controlled self-assembly and disassembly
Xiong_2012_PLoS.ONE_7_E36144A novel Escherichia coli O157:H7 clone causing a major hemolytic uremic syndrome outbreak in China
Xu_2012_Evid.Based.Complement.Alternat.Med_2012_278273Isorhamnetin, A Flavonol Aglycone from Ginkgo biloba L., Induces Neuronal Differentiation of Cultured PC12 Cells: Potentiating the Effect of Nerve Growth Factor
Xu_2012_J.Am.Chem.Soc_134_8625Bacterial biosynthesis and maturation of the didemnin anti-cancer agents
Xu_2012_J.Bacteriol_194_897Genome sequence of Enterobacter cloacae subsp. dissolvens SDM, an efficient biomass-utilizing producer of platform chemical 2,3-butanediol
Xu_2012_J.Biotechnol_162_407A two-stage enzymatic ethanol-based biodiesel production in a packed bed reactor
Xu_2012_J.Ethnopharmacol_143_109Er Zhi Wan, an ancient herbal decoction for woman menopausal syndrome, activates the estrogenic response in cultured MCF-7 cells: an evaluation of compatibility in defining the optimized preparation method
Xu_2012_J.Struct.Biol_178_363Crystal structure of a mono- and diacylglycerol lipase from Malassezia globosa reveals a novel lid conformation and insights into the substrate specificity
Xu_2012_Pharmacol.Res_68_16TNF-alpha-induced CXCL8 production by A549 cells: Involvement of the non-neuronal cholinergic system
Xu_2012_Sheng.Li.Xue.Bao_64_550A review on the current neuroligin mouse models
Xu_2012_Toxicol.Mech.Methods_22_309Chlorpyrifos exposure causes alternation in dopamine metabolism in PC12 cells
Xu_2012_Zhongguo.Zhong.Yao.Za.Zhi_37_2943[Effect of sailuotong capsule on intervening cognitive dysfunction of multi-infarct dementia in rats]
Xue_2012_PLoS.Genet_8_E1002869Comparative analysis of the genomes of two field isolates of the rice blast fungus Magnaporthe oryzae
Xue_2012_Sci.China.Life.Sci_55_132Therapeutic effects of human amniotic epithelial cell transplantation on double-transgenic mice co-expressing APPswe and PS1DeltaE9-deleted genes
Yadav_2012_Bioresour.Technol_109_1Synergism between microwave irradiation and enzyme catalysis in transesterification of ethyl-3-phenylpropanoate with n-butanol
Yakel_2012_Nicotine.Tob.Res_14_1249Nicotinic ACh receptors in the hippocampus: role in excitability and plasticity
Yamamoto_2012_PLoS.One_7_e51515Reduction of [(11)C](+)3-MPB Binding in Brain of Chronic Fatigue Syndrome with Serum Autoantibody against Muscarinic Cholinergic Receptor
Yamamoto_2012_Plant.Signal.Behav_7_301Tissue localization of maize acetylcholinesterase associated with heat tolerance in plants
Yamatoya_2012_Exp.Anim_61_467Data on Wistar Hannover rats from a general toxicity study
Yamauchi_2012_Mol.Pharmacol_82_687Synthesis of selective agonists for the alpha7 nicotinic acetylcholine receptor with in situ click-chemistry on acetylcholine-binding protein templates
Yan_2012_BMC.Genomics_13_609Transcriptomic and phylogenetic analysis of Culex pipiens quinquefasciatus for three detoxification gene families
Yan_2012_Behav.Brain.Res_230_34Nicotine-taking and nicotine-seeking in C57Bl/6J mice without prior operant training or food restriction
Yan_2012_Bioorg.Med.Chem.Lett_22_3336Quantitative structure and bioactivity relationship study on human acetylcholinesterase inhibitors
Yan_2012_Bioorg.Med.Chem_20_2527Design, synthesis and evaluation of isaindigotone derivatives as dual inhibitors for acetylcholinesterase and amyloid beta aggregation
Yan_2012_Bioresour.Technol_123_332Efficient production of biodiesel from waste grease: one-pot esterification and transesterification with tandem lipases
Yan_2012_Neurotoxicol.Teratol_34_442Repeated exposures to chlorpyrifos lead to spatial memory retrieval impairment and motor activity alteration
Yan_2012_PLoS.One_7_e30701Gene profile of myeloid-derived suppressive cells from the bone marrow of lysosomal acid lipase knock-out mice
Yan_2012_Planta.Med_78_1015Polyphenolic acetylcholinesterase inhibitors from Hopea chinensis
Yanagi_2012_Autism.Res.Treat_2012_724072Identification of Four Novel Synonymous Substitutions in the X-Linked Genes Neuroligin 3 and Neuroligin 4X in Japanese Patients with Autistic Spectrum Disorder
Yang_2012_Curr.Alzheimer.Res_9_315Tissue distribution and pharmacodynamics of rivastigmine after intranasal and intravenous administration in rats
Yang_2012_Eukaryot.Cell_11_1415Draft genome sequence of CBS 2479, the standard type strain of Trichosporon asahii
Yang_2012_Eukaryot.Cell_11_1586Genome sequence of the Trichosporon asahii environmental strain CBS 8904
Yang_2012_Food.Chem.Toxicol_50_3902Ergothioneine protects against neuronal injury induced by beta-amyloid in mice
Yang_2012_J.Bacteriol_194_6952Genome sequence of strain IMCC14465, isolated from the East Sea, belonging to the PS1 clade of Alphaproteobacteria
Yang_2012_J.Biotechnol_161_27Highly efficient biosynthesis of sucrose-6-acetate with cross-linked aggregates of Lipozyme TL 100 L
Yang_2012_J.Neurol.Sci_312_57The association of HLA-DQA1*0401 and DQB1*0604 with thymomatous myasthenia gravis in northern Chinese patients
Yang_2012_Nat.Prod.Res_26_22Geissoschizine methyl ether, a corynanthean-type indole alkaloid from Uncaria rhynchophylla as a potential acetylcholinesterase inhibitor
Yang_2012_Nat.Prod.Res_26_387An aporphine alkaloid from Nelumbo nucifera as an acetylcholinesterase inhibitor and the primary investigation for structure-activity correlations
Yang_2012_PLoS.ONE_7_E36987Edwardsiella comparative phylogenomics reveal the new intra/inter-species taxonomic relationships, virulence evolution and niche adaptation mechanisms
Yang_2012_PLoS.Pathog_8_e1002692Pdl1 is a putative lipase that enhances Photorhabdus toxin complex secretion
Yang_2012_Yao.Xue.Xue.Bao_47_313[Design of acetylcholinesterase inhibitor for Alzheimer's disease therapy: from multi-binding site inhibitors to multi-target directed ligands]
Yaniv_2012_Curr.Biol_22_1774Axon regrowth during development and regeneration following injury share molecular mechanisms
Yanovsky_2012_J.Med.Chem_55_10700Carbamate derivatives of indolines as cholinesterase inhibitors and antioxidants for the treatment of Alzheimer's disease
Yao_2012_Biochemistry_51_8980Why Does the G117H Mutation Considerably Improve the Activity of Human Butyrylcholinesterase against Sarin? Insights from Quantum Mechanical/Molecular Mechanical Free Energy Calculations
Yao_2012_J.Biol.Chem_287_34246Activation of transcription factor MEF2D by bis(3)-cognitin protects dopaminergic neurons and ameliorates Parkinsonian motor defects
Yasmin_2012_Proc.Natl.Acad.Sci.U.S.A_109_E497Mevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen Aspergillus fumigatus
Ye_2012_Biotechnol.Lett_34_1719Changing the specificity of alpha-amino acid ester hydrolase toward para-hydroxyl cephalosporins synthesis by site-directed saturation mutagenesis
Yeats_2012_Nat.Chem.Biol_8_609The identification of cutin synthase: formation of the plant polyester cutin
Yeganeh_2012_J.Bacteriol_194_2123Complete genome sequence of Oceanimonas sp. GK1, a halotolerant bacterium from Gavkhouni Wetland in Iran
Yemisci_2012_Methods.Enzymol_508_253Transport of a caspase inhibitor across the blood-brain barrier by chitosan nanoparticles
Yeo_2012_J.Bacteriol_194_536Genome sequencing of Bacillus subtilis SC-8, antagonistic to the Bacillus cereus group, isolated from traditional Korean fermented-soybean food
Yeo_2012_Neurosci_225_35Developmental expression and subcellular distribution of synaptotagmin 11 in rat hippocampus
Yeomans_2012_Handb.Exp.Pharmacol_208_243Muscarinic receptors in brain stem and mesopontine cholinergic arousal functions
Yi_2012_FEMS.Microbiol.Lett_328_100Comparative genomics of Neisseria weaveri clarifies the taxonomy of this species and identifies genetic determinants that may be associated with virulence
Yi_2012_Int.J.Mol.Sci_13_12519Effects of Genetically Engineered Stem Cells Expressing Cytosine Deaminase and Interferon-Beta or Carboxyl Esterase on the Growth of LNCaP Prostate Cancer Cells
Yi_2012_J.Bacteriol_194_3742Genome sequence of Escherichia coli J53, a reference strain for genetic studies
Yin_2012_Cardiovasc.Diabetol_11_123Several genetic polymorphisms interact with overweight/obesity to influence serum lipid levels
Yin_2012_Chemistry_18_8130Revised molecular basis of the promiscuous carboxylic acid perhydrolase activity in serine hydrolases
Yin_2012_J.Environ.Sci.(China)_24_1843Proteomic response of wheat embryos to fosthiazate stress in a protected vegetable soil
Yin_2012_Pediatr.Dev.Pathol_15_87Rectal biopsy in children with Down syndrome and chronic constipation: Hirschsprung disease vs non-hirschsprung disease
Yokoi_2012_J.Mol.Microbiol.Biotechnol_22_167Molecular properties and extracellular processing of the lipase of Staphylococcus warneri M
Yoo_2012_Molecules_17_3524Terpenoids as potential anti-Alzheimer's disease therapeutics
Yoon_2012_J.Proteome.Res_11_4413Comparative proteomic profiling of dystroglycan-associated proteins in wild type, mdx, and Galgt2 transgenic mouse skeletal muscle
Yoon_2012_Plant.Cell_24_3708Phospholipid:Diacylglycerol Acyltransferase Is a Multifunctional Enzyme Involved in Membrane Lipid Turnover and Degradation While Synthesizing Triacylglycerol in the Unicellular Green Microalga Chlamydomonas reinhardtii
Yoshida_2012_Bioorg.Med.Chem_20_5033Fused bicyclic heteroarylpiperazine-substituted L-prolylthiazolidines as highly potent DPP-4 inhibitors lacking the electrophilic nitrile group
Yoshida_2012_Bioorg.Med.Chem_20_5705Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-y lcarbonyl]thiazolidine): a highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
Young_2012_J.Appl.Toxicol_32_135Investigation of anticholinergic and non-steroidal anti-inflammatory prodrugs which reduce chemically induced skin inflammation
Young_2012_Nat.Genet_44_221Whole-genome sequence of Schistosoma haematobium
Yousefi_2012_Behav.Brain.Res_235_231Possible interaction of cholinergic and GABAergic systems between MS and CA1 upon memory acquisition in rats
Youssar_2012_Eukaryot.Cell_11_250Genome sequence of the fungus Glarea lozoyensis: the first genome sequence of a species from the Helotiaceae family
Yu_2012_J.Bacteriol_194_4757Complete genome sequence of the probiotic bacterium Bifidobacterium bifidum strain BGN4
Yu_2012_J.Bacteriol_194_6308Complete genome sequence of Bacillus subtilis strain QB928, a strain widely used in B. subtilis genetic studies
Yu_2012_J.Mol.Model_18_2869Global and local molecular dynamics of a bacterial carboxylesterase provide insight into its catalytic mechanism
Yu_2012_J.Phys.Chem.B_116_6097Delineation of the unbinding pathway of alpha-conotoxin ImI from the alpha7 nicotinic acetylcholine receptor
Yu_2012_PLoS.One_7_e46388Engineering a Disulfide Bond in the Lid Hinge Region of Rhizopus chinensis Lipase: Increased Thermostability and Altered Acyl Chain Length Specificity
Yuan_2012_PLoS.ONE_7_E34458Genome sequence and transcriptome analysis of the radioresistant bacterium Deinococcus gobiensis: insights into the extreme environmental adaptations
Yuda_2012_J.Food.Sci_77_H254Polyphenols extracted from black tea (Camellia sinensis) residue by hot-compressed water and their inhibitory effect on pancreatic lipase in vitro
Yumoto_2012_Nature_489_438Lrp4 is a retrograde signal for presynaptic differentiation at neuromuscular synapses
Zabala_2012_Chem.Biol_19_1049Characterization of a silent azaphilone gene cluster from Aspergillus niger ATCC 1015 reveals a hydroxylation-mediated pyran-ring formation
Zabrodskii_2012_Eksp.Klin.Farmakol_75_35[Disturbances of immune status and cytokine profile caused by chronic intoxication with organophosphorus compounds and their correction by administration of imunofan]
Zagoriti_2012_Clin.Dev.Immunol_2012_484919Genetics of myasthenia gravis: a case-control association study in the Hellenic population
Zaidel_2012_J.Alzheimers.Dis_31 Suppl 3_S221Donepezil effects on hippocampal and prefrontal functional connectivity in Alzheimer's disease: preliminary report
Zanaletti_2012_J.Med.Chem_55_10277N-[5-(5-fluoropyridin-3-yl)-1H-pyrazol-3-yl]-4-piperidin-1-ylbutyramide (SEN78702, WYE-308775): a medicinal chemistry effort toward an alpha7 nicotinic acetylcholine receptor agonist preclinical candidate
Zanaletti_2012_J.Med.Chem_55_4806Discovery of a novel alpha-7 nicotinic acetylcholine receptor agonist series and characterization of the potent, selective, and orally efficacious agonist 5-(4-acetyl[1,4]diazepan-1-yl)pentanoic acid [5-(4-methoxyphenyl)-1H-pyrazol-3-yl] amide (SEN15924, WAY-361789)
Zangerl_2012_J.Chem.Ecol_38_188Aliphatic esters as targets of esterase activity in the parsnip webworm (Depressaria pastinacella)
Zarros_2012_Toxicology_298_59Comments to the Editor concerning the cholinergic response to manganese-induced neurotoxicity, based on the paper entitled The inhibitory effect of manganese on acetylcholinesterase activity enhances oxidative stress and neuroinflammation in the brain by Santos et al
Zboril_2012_J.Hazard.Mater_211-212_126Treatment of chemical warfare agents by zero-valent iron nanoparticles and ferrate(VI)/(III) composite
Zeidan_2012_PLoS.One_7_e42314Neuroligin-1 loss is associated with reduced tenacity of excitatory synapses
Zeisel_2012_Ann.Nutr.Metab_61_254A brief history of choline
Zeng_2012_Zhonghua.Gan.Zang.Bing.Za.Zhi_20_746[Relation between HBsAg levels during the immune clearance phase of hepatitis B virus infection and liver pathological stages of chronic hepatitis B]
Zhai_2012_Biosens.Bioelectron_42C_124Acetylcholinesterase biosensor based on chitosan/prussian blue/multiwall carbon nanotubes/hollow gold nanospheres nanocomposite film by one-step electrodeposition
Zhai_2012_J.Hazard.Mater_221-222_206Molecular cloning, purification and biochemical characterization of a novel pyrethroid-hydrolyzing carboxylesterase gene from Ochrobactrum anthropi YZ-1
Zhai_2012_Xenobiotica_42_1151Food-drug interactions: effect of capsaicin on the pharmacokinetics of galantamine in rats
Zhang_2012_Acta.Biochim.Biophys.Sin.(Shanghai)_44_207Acetylcholinesterase is associated with apoptosis in beta cells and contributes to insulin-dependent diabetes mellitus pathogenesis
Zhang_2012_Acta.Pharmacol.Sin_33_1170New insights into huperzine A for the treatment of Alzheimer's disease
Zhang_2012_Anal.Chem_84_2830Affinity binding-guided fluorescent nanobiosensor for acetylcholinesterase inhibitors via distance modulation between the fluorophore and metallic nanoparticle
Zhang_2012_Analyst_137_716A spectroscopic off-on probe for simple and sensitive detection of carboxylesterase activity and its application to cell imaging
Zhang_2012_Appl.Environ.Microbiol_78_4848Cloning of a novel arylamidase gene from Paracoccus sp. strain FLN-7 that hydrolyzes amide pesticides
Zhang_2012_Arch.Neurol_69_445Autoantibodies to lipoprotein-related protein 4 in patients with double-seronegative myasthenia gravis
Zhang_2012_Biol.Psychiatry_71_184Withdrawal from chronic nicotine exposure alters dopamine signaling dynamics in the nucleus accumbens
Zhang_2012_Dig.Dis.Sci_57_2580Soluble epoxide hydrolase gene deficiency or inhibition attenuates chronic active inflammatory bowel disease in IL-10(-/-) mice
Zhang_2012_Drug.Metab.Dispos_40_1191Transcription factor-mediated regulation of carboxylesterase enzymes in livers of mice
Zhang_2012_Enzyme.Microb.Technol_50_325High-throughput screening of B factor saturation mutated Rhizomucor miehei lipase thermostability based on synthetic reaction
Zhang_2012_Eur.J.Pharm.Sci_47_813Analgesic effects mediated by neuronal nicotinic acetylcholine receptor agonists: correlation with desensitization of alpha4beta2* receptors
Zhang_2012_Front.Mol.Neurosci_5_40Acetylcholinesterase involvement in apoptosis
Zhang_2012_J.Agric.Food.Chem_60_6953Enantiomeric separation and toxicity of an organophosporus insecticide, pyraclofos
Zhang_2012_J.Atheroscler.Thromb_19_213Endothelial lipase mediates HDL levels in normal and hyperlipidemic rabbits
Zhang_2012_J.Bacteriol_194_6639Genome sequence of Staphylococcus epidermidis strain AU12-03, isolated from an intravascular catheter
Zhang_2012_J.Bacteriol_194_7001Genome sequence of the protease-producing bacterium Rheinheimera nanhaiensis E407-8T, isolated from deep-sea sediment of the South China Sea
Zhang_2012_J.Huazhong.Univ.Sci.Technolog.Med.Sci_32_798Dexamethasone regulates differential expression of carboxylesterase 1 and carboxylesterase 2 through activation of nuclear receptors
Zhang_2012_J.Med.Chem_55_717Chemistry and behavioral studies identify chiral cyclopropanes as selective alpha4beta2-nicotinic acetylcholine receptor partial agonists exhibiting an antidepressant profile
Zhang_2012_J.Neurosci_32_12366Impact of prefrontal cortex in nicotine-induced excitation of ventral tegmental area dopamine neurons in anesthetized rats
Zhang_2012_J.Pharmacol.Exp.Ther_343_673Identification of Human Butyrylcholinesterase Organophosphate-Resistant Variants through a Novel Mammalian Enzyme Functional Screen
Zhang_2012_Mol.Brain_5_7Wnt proteins regulate acetylcholine receptor clustering in muscle cells
Zhang_2012_Nanoscale_4_4674Biosensor based on Prussian blue nanocubes/reduced graphene oxide nanocomposite for detection of organophosphorus pesticides
Zhang_2012_Nature_490_49The oyster genome reveals stress adaptation and complexity of shell formation
Zhang_2012_Neuropsychiatr.Dis.Treat_8_571Galantamine versus donepezil in Chinese patients with Alzheimer's disease: results from a randomized, double-blind study
Zhang_2012_Neurosci_210_275Smilagenin attenuates beta amyloid (25-35)-induced degeneration of neuronal cells via stimulating the gene expression of brain-derived neurotrophic factor
Zhang_2012_Parasit.Vectors_5_209Identification of resistant carboxylesterase alleles in Culex pipiens complex via PCR-RFLP
Zhang_2012_Phytomedicine_19_1042Chemical and biological assessment of Angelica herbal decoction: comparison of different preparations during historical applications
Zhang_2012_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_92_283Biophysical influence of isocarbophos on bovine serum albumin: spectroscopic probing
Zhang_2012_Yao.Xue.Xue.Bao_47_1141[Inhibitory effect of icariin on acetylcholinesterase]
Zhao_2012_Am.J.Physiol.Cell.Physiol_303_C427Identification of a novel intracellular cholesteryl ester hydrolase (carboxylesterase 3) in human macrophages: compensatory increase in its expression after carboxylesterase 1 silencing
Zhao_2012_Aquaculture_368-369_117Effects of dietary isoleucine on growth, the digestion and absorption capacity and gene expression in hepatopancreas and intestine of juvenile Jian carp (Cyprinus carpio var. Jian)
Zhao_2012_Environ.Toxicol.Pharmacol_35_228Quantitative structure-activity relationship of organophosphate compounds based on molecular interaction fields descriptors
Zhao_2012_Eukaryot.Cell_11_1178Draft genome sequence of Aspergillus oryzae strain 3.042
Zhao_2012_Int.J.Cardiol_155_181Soluble epoxide hydrolase and ischemic cardiomyopathy
Zhao_2012_J.Biol.Chem_287_11141CutA divalent cation tolerance homolog (Escherichia coli) (CUTA) regulates beta-cleavage of beta-amyloid precursor protein (APP) through interacting with beta-site APP cleaving protein 1 (BACE1)
Zhao_2012_Stem.Cells_30_314Human neural stem cell tropism to metastatic breast cancer
Zhao_2012_Tumour.Biol_33_523System review and metaanalysis of the relationships between five metabolic gene polymorphisms and colorectal adenoma risk
Zhao_2012_Zhonghua.Xin.Xue.Guan.Bing.Za.Zhi_40_248[Soluble epoxide hydrolase inhibitor t-AUCB ameliorates ox-LDL induced conversion of macrophages into foam cells through activating the PPARgamma-ABCA1 pathway]
Zhaxybayeva_2012_Genome.Biol.Evol_4_700Genome sequence of the mesophilic Thermotogales bacterium Mesotoga prima MesG1.Ag.4.2 reveals the largest Thermotogales genome to date
Zheng_2012_Bioresour.Technol_110_224Lipase-coated K2SO4 micro-crystals: preparation, characterization, and application in biodiesel production using various oil feedstocks
Zheng_2012_Bioresour.Technol_115_141Immobilization of Candida rugosa lipase on hydrophobic/strong cation-exchange functional silica particles for biocatalytic synthesis of phytosterol esters
Zheng_2012_Curr.Drug.Targets_13_1089Novel chelators targeting cell cycle arrest, acetylcholinesterase, and monoamine oxidase for Alzheimer's therapy
Zheng_2012_Eur.J.Pharmacol_679_34Salidroside stimulates the accumulation of HIF-1alpha protein resulted in the induction of EPO expression: a signaling via blocking the degradation pathway in kidney and liver cells
Zheng_2012_Int.J.Biol.Macromol_53C_54Probing the molecular determinant of the lipase-specific foldase Lif26 for the interaction with its cognate Lip26
Zheng_2012_J.Alzheimers.Dis_30_1From anti-Parkinson's drug rasagiline to novel multitarget iron chelators with acetylcholinesterase and monoamine oxidase inhibitory and neuroprotective properties for Alzheimer's disease
Zheng_2012_J.Mol.Microbiol.Biotechnol_22_300Molecular Cloning and Heterologous Expression of a True Lipase in Pichia pastoris Isolated via a Metagenomic Approach
Zheng_2012_J.Pharm.Biomed.Anal_70_671The membrane permeability of Astragali Radix-derived formononetin and calycosin is increased by Angelicae Sinensis Radix in Caco-2 cells: a synergistic action of an ancient herbal decoction Danggui Buxue Tang
Zheng_2012_Mini.Rev.Med.Chem_12_364From antioxidant chelators to site-activated multi-target chelators targeting hypoxia inducing factor, beta-amyloid, acetylcholinesterase and monoamine oxidase A/B
Zheng_2012_PLoS.Comput.Biol_8_e1002610Modeling of pharmacokinetics of cocaine in human reveals the feasibility for development of enzyme therapies for drugs of abuse
Zheng_2012_Toxicol.Appl.Pharmacol_264_65Novel bis-(-)-nor-meptazinol derivatives act as dual binding site AChE inhibitors with metal-complexing property
Zhou_2012_Acta.Biochim.Biophys.Sin.(Shanghai)_44_965Alteration of substrate specificities of thermophilic alpha/beta hydrolases through domain swapping and domain interface optimization
Zhou_2012_Ecotoxicology_21_2297Does glyphosate impact on Cu uptake by, and toxicity to, the earthworm Eisenia fetida?
Zhou_2012_Fish.Physiol.Biochem_38_849Erythrocyte damage of crucian carp (Carassius auratus) caused by microcystin-LR: in vitro study
Zhou_2012_J.Bacteriol_194_1261Draft genome sequence of Mesorhizobium alhagi CCNWXJ12-2T, a novel salt-resistant species isolated from the desert of northwestern China
Zhu_2012_BMC.Genomics_13_382Sequencing the genome of Marssonina brunnea reveals fungus-poplar co-evolution
Zhu_2012_Evid.Based.Complement.Alternat.Med_2012_149256A standardized chinese herbal decoction, kai-xin-san, restores decreased levels of neurotransmitters and neurotrophic factors in the brain of chronic stress-induced depressive rats
Zhu_2012_Evol.Bioinform.Online_8_105Interkingdom gene transfer may contribute to the evolution of phytopathogenicity in botrytis cinerea
Zhu_2012_J.Bacteriol_194_6963Genome sequence of Enterobacter sp. strain SP1, an endophytic nitrogen-fixing bacterium isolated from sugarcane
Zhu_2012_Nat.Commun_3_1112A multi-omic map of the lipid-producing yeast Rhodosporidium toruloides
Zhu_2012_PLoS.One_7_e37586Microarray analysis of gene regulations and potential association with acephate-resistance and fitness cost in Lygus lineolaris
Zhu_2012_Pharmacogenet.Genomics_22_215A discriminative analytical method for detection of CES1A1 and CES1A2/CES1A3 genetic variants
Zhuravleva_2012_Mol.Cell.Biol_32_2685Acyl coenzyme A thioesterase Them5/Acot15 is involved in cardiolipin remodeling and fatty liver development
Zichel_2012_PLoS.One_7_e31948Aptamers as a sensitive tool to detect subtle modifications in therapeutic proteins
Ziemianin_2012_J.Pharm.Biomed.Anal_70_1Screening of new huprines--inhibitors of acetylcholinesterases by electrospray ionization ion trap mass spectrometry
Zilles_2012_J.Clin.Psychopharmacol_32_422Successful treatment of musical hallucinations with the acetylcholinesterase inhibitor donepezil
Zimmer_2012_Int.J.Environ.Health.Res_22_279Influence of physical exercise and gender on acetylcholinesterase and butyrylcholinesterase activity in human blood samples
Zimmermann_2012_PLoS.Biol_10_e1001429Inhibition of the prokaryotic pentameric ligand-gated ion channel ELIC by divalent cations
Zischka_2012_J.Bacteriol_194_5490Complete genome sequence of the porcine isolate Enterococcus faecalis D32
Znati_2012_Nat.Prod.Commun_7_947Chemical composition and in vitro evaluation of antimicrobial and anti-acetylcholinesterase properties of the flower oil of Ferula lutea
Zoli_2012_Nicotine.Tob.Res_14_1270Nicotinic regulation of energy homeostasis
Zomer_2012_J.Bacteriol_194_6969Genome sequence of Moraxella catarrhalis RH4, an isolate of seroresistant lineage
Zong_2012_Genes.Dev_26_247Structural basis of agrin-LRP4-MuSK signaling
Zoropogui_2012_J.Bacteriol_194_2098Genome sequence of the human- and animal-pathogenic strain Nocardia cyriacigeorgica GUH-2
Zou_2012_J.Agric.Food.Chem_60_9415Preparation of human milk fat substitutes from palm stearin with arachidonic and docosahexaenoic acid: combination of enzymatic and physical methods
Zuhl_2012_J.Am.Chem.Soc_134_5068Competitive activity-based protein profiling identifies aza-beta-lactams as a versatile chemotype for serine hydrolase inhibition
Zwick_2012_Genome.Res_22_1512Genomic characterization of the Bacillus cereus sensu lato species: backdrop to the evolution of Bacillus anthracis
da Cunha_2012_Neurochem.Res_37_1660Chronic hyperhomocysteinemia increases inflammatory markers in hippocampus and serum of rats
da Rocha_2012_Behav.Pharmacol_23_98Diphenyl diselenide ameliorates cognitive deficits induced by a model of menopause in rats
da Silva_2012_J.Med.Microbiol_61_278Cholinesterases as markers of the inflammatory process in rats infected with Leptospira interrogans serovar Icterohaemorrhagiae
da Silva_2012_J.Pharm.Biomed.Anal_73_44Acetylcholinesterase capillary enzyme reactor for screening and characterization of selective inhibitors
de Andrade Brito_2012_J.Environ.Monit_14_615Monitoring water quality in reservoirs for human supply through multi-biomarker evaluation in tropical fish
de Andrade_2012_J.Pharm.Biomed.Anal_70_13Bioactive alkaloid extracts from Narcissus broussonetii: Mass spectral studies
de Araujo Furtado_2012_Neurotoxicol_33_1476Exposure to nerve agents: From status epilepticus to neuroinflammation, brain damage, neurogenesis and epilepsy
de Diego_2012_Biochem.Biophys.Res.Commun_428_482Smaller quantal size and faster kinetics of single exocytotic events in chromaffin cells from the APP/PS1 mouse model of Alzheimer's disease
de Oliveira Cunha_2012_J.Bacteriol_194_6675Complete genome sequence of Burkholderia phenoliruptrix BR3459a (CLA1), a heat-tolerant, nitrogen-fixing symbiont of Mimosa flocculosa
de Oliveira_2012_Clin.Hemorheol.Microcirc_51_129Cell-specific regulation of acetylcholinesterase expression under inflammatory conditions
de Pascale_2012_Mar.Genomics_8_15The microbial diversity of Polar environments is a fertile ground for bioprospecting
de Sa Morais_2012_J.Bacteriol_194_2772Complete genome sequence of a sucrose-nonfermenting epidemic strain of Vibrio cholerae O1 from Brazil
de Souza_2012_Molecules_17_9529Hologram QSAR models of 4-[(diethylamino)methyl]-phenol inhibitors of acetyl/butyrylcholinesterase enzymes as potential anti-Alzheimer agents
de Vasconcelos_2012_Neurosci.Lett_525_34Large litters rearing changes brain expression of GLUT3 and acetylcholinesterase activity in adult rats
de Wit_2012_PLoS.Genet_8_E1003088The genomes of the fungal plant pathogens Cladosporium fulvum and Dothistroma septosporum reveal adaptation to different hosts and lifestyles but also signatures of common ancestry
de los Rios_2012_Expert.Opin.Ther.Pat_22_853Cholinesterase inhibitors: a patent review (2007 - 2011)
del Loandos_2012_Nat.Prod.Commun_7_1117Catalytic and molecular properties of rabbit liver carboxylesterase acting on 1,8-cineole derivatives
den Bakker_2012_Appl.Environ.Microbiol_78_1876FSL J1-208, a virulent uncommon phylogenetic lineage IV Listeria monocytogenes strain with a small chromosome size and a putative virulence plasmid carrying internalin-like genes
do Carmo_2012_Nutr.Metab.Cardiovasc.Dis_22_598Inhibition of soluble epoxide hydrolase reduces food intake and increases metabolic rate in obese mice


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer