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Year Report for: 2020

Aakko_2020_Sci.Rep_10_12411A carbohydrate-active enzyme (CAZy) profile links successful metabolic specialization of Prevotella to its abundance in gut microbiota
Abaukaka_2020_Environ.Anal.Health.Toxicol_35_e2020016Assessment of the cytotoxic and mutagenic potential of dichlorvos (DDVP) using in silico classification model; a health hazard awareness in Nigeria
Abbas-Mohammadi_2020_J.Biomol.Struct.Dyn__1Molecular networking based dereplication of AChE inhibitory compounds from the medicinal plant Vincetoxicum funebre (Boiss. & Kotschy)
Abbasi-Jorjandi_2020_Environ.Pollut_267_115424Pesticide exposure and related health problems among family members of farmworkers in southeast Iran. A case-control study
Abbod_2020_Pestic.Biochem.Physiol_164_228Mode of action of 3-butylidene phthalide as a competent natural pesticide
Abd_2020_Environ.Sci.Pollut.Res.Int__Single or combined exposure to chlorpyrifos and cypermethrin provoke oxidative stress and downregulation in monoamine oxidase and acetylcholinesterase gene expression of the rat's brain
Abdel-Daim_2020_Environ.Sci.Pollut.Res.Int_27_10228Protective effects of thymoquinone and diallyl sulphide against malathion-induced toxicity in rats
Abdel-Daim_2020_Environ.Sci.Pollut.Res.Int_27_11554Fucoidan protects against subacute diazinon-induced oxidative damage in cardiac, hepatic, and renal tissues
Abdel-Rafei_2020_Life.Sci__118410Modulatory effect of methylsulfonylmethane against BPA/gamma-radiation induced neurodegenerative alterations in rats: Influence of TREM-2/DAP-12/Syk pathway
Abdel_2020_Molecules_25_Flavonol Glycosides: In Vitro Inhibition of DPPIV, Aldose Reductase and Combating Oxidative Stress are Potential Mechanisms for Mediating the Antidiabetic Activity of Cleome droserifolia
Abdellaoui_2020_Pestic.Biochem.Physiol_167_104594The aggregation pheromone phenylacetonitrile: Joint action with the entomopathogenic fungus Metarhizium anisopliae var. acridum and physiological and transcriptomic effects on Schistocerca gregaria nymphs
Abdizadeh_2020_Med.Chem_16_903Molecular Modeling Studies of Anti-Alzheimer Agents by QSAR, Molecular Docking and Molecular Dynamics Simulations Techniques
Abdul_2020_PeerJ_8_e10003Explicating anti-amyloidogenic role of curcumin and piperine via amyloid beta (Abeta) explicit pathway: recovery and reversal paradigm effects
Abdullaev_2020_Mol.Biol.Rep_47_3377Clinically relevant pharmacogenetic markers in Tatars and Balkars
Abdullaha_2020_Eur.J.Med.Chem_207_112761Discovery of methoxy-naphthyl linked N-(1-benzylpiperidine) benzamide as a blood-brain permeable dual inhibitor of acetylcholinesterase and butyrylcholinesterase
Aberg_2020_Mol.Psychiatry_25_1344Methylome-wide association findings for major depressive disorder overlap in blood and brain and replicate in independent brain samples
Abeysinghe_2020_Life.Sci__117996Alzheimer's disease; a review of the pathophysiological basis and therapeutic interventions
Abidar_2020_Antioxidants.(Basel)_9_The Aqueous Extract from Ceratonia siliqua Leaves Protects Against 6-hydroxydopamine in Zebrafish: Understanding the Underlying Mechanism
Aboelwafa_2020_Brain.Sci_10_The Possible Neuroprotective Effect of Silymarin against Aluminum Chloride-Prompted Alzheimer's-Like Disease in Rats
Abohalaka_2020_Pulm.Pharmacol.Ther__101920The Effects of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase Inhibitor treatments on Lipopolysaccharide-induced Airway Inflammation in Mice
Abolaji_2020_Toxicol.Rep_7_261Curcumin attenuates copper-induced oxidative stress and neurotoxicity in Drosophila melanogaster
Abolaji_2020_Toxicol.Res.(Camb)_9_346D-Penicillamine prolongs survival and lessens copper-induced toxicity in Drosophila melanogaster
Abou-Donia_2020_Mil.Med_185_383Novel Approach for Detecting the Neurological or Behavioral Impact of Physiological Episodes (PEs) in Military Aircraft Crews
Abrahams_2020_Cell.Surf_6_100040Anti-tubercular derivatives of rhein require activation by the monoglyceride lipase Rv0183
Abu-Taweel_2020_Curr.Pharm.Biotechnol_21_1316Effects of Perinatal Cardamom Exposure on Social Behavior, Anxiety, Locomotor Activity, Blood Biochemical Parameters and Brain Acetylcholinesterase of Mice Offspring
Acero-Sandoval_2020_Salud.Publica.Mex_62_402Determination of insecticides' lethal concentrations and metabolic enzyme levels in Triatoma dimidiata
Achili_2020_Recent.Pat.Food.Nutr.Agric__Chemical constituents, antioxidant, anticholinesterase and antiproliferative effects of Algerian Pistacia atlantica Desf. extracts
Achouri_2020_Biomed.Res.Int_2020_3064290Dissecting the Interaction Deficiency of a Cartilaginous Fish Digestive Lipase with Pancreatic Colipase: Biochemical and Structural Insights
Adachi_2020_Int.Immunol_32_637Lung fibroblasts produce IL-33 in response to stimulation with retinoblastoma-binding protein 9 via production of prostaglandin E2
Adalat_2020_Molecules_25_Synthesis of Benzimidazole-Based Analogs as Anti Alzheimer's Disease Compounds and Their Molecular Docking Studies
Adam_2020_BMJ.Open_10_e031212Cholinesterase alterations in delirium after cardiosurgery: a German monocentric prospective study
Adam_2020_J.Lipid.Res_61_1271Angiopoietin-like protein 3 governs LDL-cholesterol levels through endothelial lipase-dependent VLDL clearance
Adams_2020_Reprod.Toxicol_94_65Sex- and age-dependent effects of maternal organophosphate flame-retardant exposure on neonatal hypothalamic and hepatic gene expression
Adant_2020_J.Hepatol_72_1030Two cases of non-alcoholic fatty liver disease caused by biallelic ABHD5 mutations
Adedara_2020_Chemosphere_264_128449Toxicological outcome of exposure to psychoactive drugs carbamazepine and diazepam on non-target insect Nauphoeta cinerea
Adedara_2020_Environ.Pollut_265_115053Hazardous impact of diclofenac exposure on the behavior and antioxidant defense system in Nauphoeta cinerea
Adedara_2020_J.Biochem.Mol.Toxicol__e22684Neuroprotective role of gallic acid in aflatoxin B(1) -induced behavioral abnormalities in rats
Adedara_2020_Neurotoxicol_76_99Neuroprotective mechanisms of selenium against arsenic-induced behavioral impairments in rats
Adedayo_2020_Drug.Chem.Toxicol__1Effect of Andrographis paniculata and Phyllanthus amarus leaf extracts on selected biochemical indices in Drosophila melanogaster model of neurotoxicity
Adedayo_2020_J.Food.Biochem__e13280Effect of Andrographis paniculata leaves extract on neurobehavioral and biochemical indices in scopolamine-induced amnesic rats
Adedeji_2020_Parasit.Vectors_13_465Anopheles metabolic proteins in malaria transmission, prevention and control: a review
Adefegha_2020_J.Food.Biochem__e13276Antioxidant properties of eugenol, butylated hydroxylanisole, and butylated hydroxyl toluene with key biomolecules relevant to Alzheimer's diseases-In vitro
Ademiluyi_2020_J.Food.Biochem__e13451Dietary monosodium glutamate altered redox status and dopamine metabolism in lobster cockroach (Nauphoeta cinerea)
Ademosun_2020_Drug.Chem.Toxicol__1Shaddock (Citrus maxima) peels extract restores cognitive function, cholinergic and purinergic enzyme systems in scopolamine-induced amnesic rats
Adeowo_2020_J.Biomol.Struct.Dyn__1Multi-target approach for Alzheimer's disease treatment: computational biomolecular modeling of cholinesterase enzymes with a novel 4-N-phenylaminoquinoline derivative reveal promising potentials
Adesanoye_2020_Food.Chem.Toxicol__111478Luteolin-Supplemented Diets Ameliorates Bisphenol A-Induced Toxicity in Drosophila melanogaster
Adeshina_2020_Proc.Natl.Acad.Sci.U.S.A_117_18477Machine learning classification can reduce false positives in structure-based virtual screening
Adlan_2020_Front.Microbiol_11_565608Microbial Biodegradation of Paraffin Wax in Malaysian Crude Oil Mediated by Degradative Enzymes
Adnet_2020_Pharmaceutics_12_Pharmacotechnical Development of a Nasal Drug Delivery Composite Nanosystem Intended for Alzheimer's Disease Treatment
Afolabi_2020_BMC.Res.Notes_13_217High concentration of MSG alters antioxidant defence system in lobster cockroach Nauphoeta cinerea (Blattodea: Blaberidae)
Afsharnezhad_2020_Iran.Biomed.J_25_21Inhibitory Potential of Acroptilon repens against Key Enzymes involved in Alzheimer and Diabetes, Phytochemical Profile, Radical Scavenging, and Antibacterial Activity
Agbo_2020_Bioorg.Chem_101_103997Synthesis of furocoumarin-stilbene hybrids as potential multifunctional drugs against multiple biochemical targets associated with Alzheimer's disease
Agrawal_2020_Food.Chem.Toxicol__111684Phycocyanin alleviates ICV-STZ induced cognitive and molecular deficits via PI3-Kinase dependent pathway
Agunloye_2020_J.Complement.Integr.Med_18_67High cholesterol diet promotes dysfunction of arginase and cholinergic enzymatic system in rats: ameliorative role of caffeic and chlorogenic acids
Agunloye_2020_J.Diet.Suppl__1Pleurotus ostreatus and Lentinus subnudus supplemented diets restore altered acetylcholinesterase and butyrylcholinesterase activities and improve antioxidant status in transgenic Drosophila melanogaster model
Agunloye_2020_J.Food.Biochem__e13355Effect of diet supplemented with P. ostreatus and L. subnudus on memory index and key enzymes linked with Alzheimer's disease in streptozotocin-induced diabetes rats
Ahire_2020_Psychoneuroendocrinology_124_105066The potential involvement of cholinergic system in finasteride induced cognitive dysfunction
Ahmad_2020_Drug.Des.Devel.Ther_14_2165Comparative Cholinesterase, alpha-Glucosidase Inhibitory, Antioxidant, Molecular Docking, and Kinetic Studies on Potent Succinimide Derivatives
Ahmad_2020_Front.Plant.Sci_11_848Genome-Wide Analysis of Serine Carboxypeptidase-Like Acyltransferase Gene Family for Evolution and Characterization of Enzymes Involved in the Biosynthesis of Galloylated Catechins in the Tea Plant (Camellia sinensis)
Ahmad_2020_J.Ayurveda.Integr.Med_11_471Protective role of hydroalcoholic extract of Cajanus cajan Linn leaves against memory impairment in sleep deprived experimental rats
Ahmad_2020_J.Basic.Clin.Physiol.Pharmacol__Phytochemical profile and pharmacological properties of Trifolium repens
Ahmad_2020_Mol.Biol.Rep_47_9553Synthetic beta-hydroxy ketone derivative inhibits cholinesterases, rescues oxidative stress and ameliorates cognitive deficits in 5XFAD mice model of AD
Ahmad_2020_Molecules_25_The Role of Surface Exposed Lysine in Conformational Stability and Functional Properties of Lipase from Staphylococcus Family
Ahmadi_2020_J.Arthropod.Borne.Dis_14_344Dichlorvos Resistance in the House Fly Populations, Musca domestica, of Iranian Cattle Farms
Ahmed_2020_Animals.(Basel)_10_Biochemical and Histopathological Alterations in Different Tissues of Rats Due to Repeated Oral Dose Toxicity of Cymoxanil
Ahmed_2020_Chem.Phys.Lipids_231_104931ATR-IR and EPR spectroscopy for following the membrane restoration of isolated cortical synaptosomes in aluminium-induced Alzheimer's disease - Like rat model
Ahmed_2020_Ecotoxicol.Environ.Saf_209_111820Neuromodulatory effect of cinnamon oil on behavioural disturbance, CYP1A1, iNOStranscripts and neurochemical alterations induced by deltamethrin in rat brain
Ahnaou_2020_Neural.Plast_2020_6249375In Vivo Plasticity at Hippocampal Schaffer Collateral-CA1 Synapses: Replicability of the LTP Response and Pharmacology in the Long-Evans Rat
Ahvo_2020_Mar.Environ.Res_162_105097The use of Atlantic hagfish (Myxine glutinosa) as a bioindicator species for studies on effects of dumped chemical warfare agents in the Skagerrak. 2. Biochemical biomarkers
Ait-Bali_2020_Arch.Toxicol__Pre- and postnatal exposure to glyphosate-based herbicide causes behavioral and cognitive impairments in adult mice: evidence of cortical ad hippocampal dysfunction
Ajatta_2020_J.Food.Biochem__e13473Cognitive impairment by non-insulin-dependent diabetes mellitus was attenuated by dietary supplements of marble vine (Dioclea reflexa) and plantain (Musa paradisiaca) dough meals in albino rats
Akhoon_2020_J.Chem.Inf.Model_60_4717Discovery of a New Donepezil-like Acetylcholinesterase Inhibitor for Targeting Alzheimer's Disease: Computational Studies with Biological Validation
Akhtar_2020_Brain.Res.Bull_164_83Sodium orthovanadate improves learning and memory in intracerebroventricular-streptozotocin rat model of Alzheimer's disease through modulation of brain insulin resistance induced tau pathology
Akil_2020_Int.J.Biol.Macromol_163_910Efficient production of bioactive structured lipids by fast acidolysis catalyzed by Yarrowia lipolytica lipase, free and immobilized in chitosan-alginate beads, in solvent-free medium
Akimov_2020_Biomolecules_10_Arachidonoylcholine and Other Unsaturated Long-Chain Acylcholines Are Endogenous Modulators of the Acetylcholine Signaling System
Akin_2020_Bioorg.Chem_104_104279Synthesis of N-phenylsulfonamide derivatives and investigation of some esterase enzymes inhibiting properties
Akincioglu_2020_Mini.Rev.Med.Chem_20_703Potent Acetylcholinesterase Inhibitors: Potential Drugs for Alzheimer's Disease
Akintunde_2020_Curr.Ther.Res.Clin.Exp_92_100586Potential Protective Effects of Naringin on Oculo-Pulmonary Injury Induced by PM10 (Wood Smoke) Exposure by Modulation of Oxidative Damage and Acetylcholine Esterase Activity in a Rat Model
Akkus_2020_Acta.Gastroenterol.Belg_83_585Development of pancreatic injuries in the course of COVID-19
Akomolafe_2020_Neurotox.Res__Curcumin Administration Mitigates Cyclophosphamide-Induced Oxidative Damage and Restores Alteration of Enzymes Associated with Cognitive Function in Rats' Brain
Aksoz_2020_Comb.Chem.High.Throughput.Screen__Vital Role of MAO and ChE in CNS Drug Research: A Sharp Dissection of the Pathophysiology
Aksu_2020_Arch.Pharm.(Weinheim)__e2000254Concise syntheses and some biological activities of dl-2,5-di-O-methyl-chiro-inositol, dl-1,4-di-O-methyl-scyllo-inositol, and dl-1,6-dibromo-1,6-dideoxy-2,5-di-O-methyl-chiro-inositol
Al Mamun_2020_Biomolecules_10_Amaryllidaceae Alkaloids of Belladine-Type from Narcissus pseudonarcissus cv. Carlton as New Selective Inhibitors of Butyrylcholinesterase
Al Naggar_2020_Environ.Sci.Pollut.Res.Int_27_19004Sublethal effects of chronic exposure to CdO or PbO nanoparticles or their binary mixture on the honey bee (Apis millefera L.)
Al Olayan_2020_Sci.Total.Environ_723_137969Protocatechuic acid mitigates cadmium-induced neurotoxicity in rats: Role of oxidative stress, inflammation and apoptosis
Al-Amin_2020_Parasit.Vectors_13_622Insecticide resistance status of Aedes aegypti in Bangladesh
Al-Hage_2020_Clin.Exp.Dermatol_45_257Chanarin-Dorfman syndrome: a novel homozygous mutation in the ABHD5 gene
Al-Hamed_2020_Biomolecules_10_Postoperative Administration of the Acetylcholinesterase Inhibitor, Donepezil, Interferes with Bone Healing and Implant Osseointegration in a Rat Model
Al-Huqail_2020_Fresenius.Environ.Bull_29_6871Bioactiv molecules from Dodder cuszcuta sp. Parasitic bridge: a critical parameters in the management of plant virusdisease
Al-Okbi_2020_J.Oleo.Sci_69_771Fish Oil and Primrose Oil Suppress the Progression of Alzheimer's Like Disease Induced by Aluminum in Rats
Al-Quraishy_2020_Environ.Sci.Pollut.Res.Int__Myristica fragrans seed extract reverses scopolamine-induced cortical injury via stimulation of HO-1 expression in male rats
Al-Thuwaini_2020_Trop.Anim.Health.Prod_52_3631Co-inherited novel SNPs of the LIPE gene associated with increased carcass dressing and decreased fat-tail weight in Awassi breed
AlKahtane_2020_Environ.Sci.Pollut.Res.Int__Carnosic acid alleviates chlorpyrifos-induced oxidative stress and inflammation in mice cerebral and ocular tissues
Alagoz_2020_Exp.Ther.Med_19_3505A novel mutation in the SERAC1 gene correlates with the severe manifestation of the MEGDEL phenotype, as revealed by whole-exome sequencing
Alaneed_2020_J.Pharm.Sci_109_981Conjugation of Amine-Functionalized Polyesters With Dimethylcasein Using Microbial Transglutaminase
Alayadhi_2020_Med.Princ.Pract__Elevated plasma X-linked neuroligin 4 expression is associated with autism spectrum disorder
Albasher_2020_Oxid.Med.Cell.Longev_2020_2963020Red Beetroot Extract Abrogates Chlorpyrifos-Induced Cortical Damage in Rats
Albayati_2020_Catalysts_10_747Main Structural Targets for Engineering Lipase Substrate Specificity
Albazal_2020_J.Chem.Neuroanat_112_101902Melatonin reverses cognitive deficits in streptozotocin-induced type 1 diabetes in the rat through attenuation of oxidative stress and inflammation
Alberga_2020_J.Chem.Inf.Model_60_4582De novo drug design of targeted chemical libraries based on artificial intelligence and pair based multi-objective optimization
Alhowail_2020_Eur.Rev.Med.Pharmacol.Sci_24_11858Role of the purinergic P2Y2 receptor in hippocampal function in mice
Ali_2020_BMC.Complement.Med.Ther_20_313Metabolic fingerprinting, antioxidant characterization, and enzyme-inhibitory response of Monotheca buxifolia (Falc.) A. DC. extracts
Ali_2020_Bioresour.Technol_313_123631Construction of a new lipase- and xylanase-producing oleaginous yeast consortium capable of reactive azo dye degradation and detoxification
Ali_2020_Sci.Signal_13_Neuroligin-2 as a central organizer of inhibitory synapses in health and disease
Ali_2020_Toxins.(Basel)_12_27Calcium-Induced Activity and Folding of a Repeat in Toxin Lipase from Antarctic Pseudomonas fluorescens Strain AMS8
Ali_2020_Toxins.(Basel)_12_579The Influence of Calcium toward Order/Disorder Conformation of Repeat-in-Toxin (RTX) Structure of Family I.3 Lipase from Pseudomonas fluorescens AMS8
Aliche_2020_New.Phytol_227_1001Science and application of strigolactones
Alinaghian_2020_Gene_725_144152Corrigendum to Gender-related relation between metabolic syndrome and S447X and HindIII polymorphisms of lipoprotein lipase gene in northern Iran [Gene 706 (2019) 13-18]
Alioto_2020_Plant.J_101_455Transposons played a major role in the diversification between the closely related almond and peach genomes: results from the almond genome sequence
Aljuaid_2020_Saudi.J.Med.Med.Sci_8_174Association of Four Missense SNPs with Preeclampsia in Saudi Women
Alkan_2020_Environ.Sci.Pollut.Res.Int_27_35626Acute exposure to the fungicide penconazole affects some biochemical parameters in the crayfish (Astacus leptodactylus Eschscholtz, 1823)
Alkan_2020_J.Fungi.(Basel)_6_Chemical Characterization, Antioxidant, Enzyme Inhibition and Antimutagenic Properties of Eight Mushroom Species: A Comparative Study
Almadiy_2020_Environ.Sci.Pollut.Res.Int_27_41568Chemical profile, mosquitocidal, and biochemical effects of essential oil and major components of Dysphania ambrosioides against Culex quinquefasciatus Say
Almadiy_2020_Heliyon_6_e04915Chemical composition, insecticidal and biochemical effects of two plant oils and their major fractions against Aedes aegypti, the common vector of dengue fever
Almami_2020_Arch.Toxicol_94_3861Neurite outgrowth inhibitory levels of organophosphates induce tissue transglutaminase activity in differentiating N2a cells: evidence for covalent adduct formation
Almasri_2020_Ecotoxicol.Environ.Saf_203_111013Mixtures of an insecticide, a fungicide and a herbicide induce high toxicities and systemic physiological disturbances in winter Apis mellifera honey bees
Almeer_2020_Comb.Chem.High.Throughput.Screen__Ziziphus spina-christi leaf extract mitigates mercuric chloride-induced cortical damage in rats
Almeida_2020_Biomolecules_10_Structure-Antifouling Activity Relationship and Molecular Targets of Bio-Inspired(thio)xanthones
Alston_2020_J.Anesth.Hist_6_3Eponymous plot of Richard J. Kitz and Irwin B. Wilson in biochemistry
Alsuhebani_2020_J.Anesth__Heart rate changes following the administration of sugammadex in children: a prospective, observational study
Altamimi_2020_Chem.Biol.Drug.Des_96_1418Pyrrolidin-2-one linked benzofused heterocycles as novel small molecule monoacylglycerol lipase inhibitors and antinociceptive agents
Alteba_2020_Eur.Neuropsychopharmacol_39_70Antidepressant-like effects of URB597 and JZL184 in male and female rats exposed to early life stress
Aluko_2020_Naunyn.Schmiedebergs.Arch.Pharmacol__Methyl jasmonate reverses chronic stress-induced memory dysfunctions through modulation of monoaminergic neurotransmission, antioxidant defense system, and Nrf2 expressions
Alvarenga_2020_ACS.Catal_10_1607Asymmetric Synthesis of Dihydropinidine Enabled by Concurrent Multienzyme Catalysis and a Biocatalytic Alternative to Krapcho Dealkoxycarbonylation
Alvi_2020_Pak.J.Pharm.Sci_33_2779Appraisal of organic extracts and isolated compounds of Azadirachta indica for in-vitro antioxidant, acetylcholinesterase and butyrylcholinesterase inhibitory activity
Alzahrani_2020_Saudi.Pharm.J_28_574Possible combined effect of perindopril and Azilsartan in an experimental model of dementia in rats
Amat-Ur-Rasool_2020_Biomolecules_10_Potential Nutraceutical Properties of Leaves from Several Commonly Cultivated Plants
Amend_2020_Ann.N.Y.Acad.Sci__Diagnostics and treatment of nerve agent poisoning-current status and future developments
Amend_2020_Arch.Toxicol__A case report of cholinesterase inhibitor poisoning: cholinesterase activities and analytical methods for diagnosis and clinical decision making
Amin_2020_Cureus_12_e10248Myasthenia Gravis and its Association With Thyroid Diseases
Amin_2020_Steroids__108599SAR based in-vitro anticholinesterase and molecular docking studies of nitrogenous progesterone derivatives
Amine_2020_Mol.Divers__Synthesis, biological evaluation, theoretical investigations, docking study and ADME parameters of some 1,4-bisphenylhydrazone derivatives as potent antioxidant agents and acetylcholinesterase inhibitors
Amri_2020_Fish.Physiol.Biochem_46_2265Effect of melatonin and folic acid supplementation on the growth performance, antioxidant status, and liver histology of the farmed gilthead sea bream (Sparus aurata L.) under standard rearing conditions
An_2020_Int.J.Mol.Sci_21_5064Targeting Cannabinoid Receptors: Current Status and Prospects of Natural Products
An_2020_Int.J.Mol.Sci_21_658Analysis of Differentially Expressed Transcripts in Apolygus lucorum (Meyer-Dur) Exposed to Different Temperature Coefficient Insecticides
An_2020_Korean.J.Anesthesiol_73_137Neuromuscular blockade reversal with sugammadex versus pyridostigmine/glycopyrrolate in laparoscopic cholecystectomy: a randomized trial of effects on postoperative gastrointestinal motility
Anbarkeh_2020_Toxicology__152583The protective role of alpha-lipoic acid on the appearance of fibronectin and laminin in renal tubules following diazinon exposure: an experimental immunohistochemical study
Andersson_2020_J.Phys.Chem.B_124_6529Physical Mechanisms Governing Substituent Effects on Arene-Arene Interactions in a Protein Milieu
Andrabi_2020_J.Environ.Pathol.Toxicol.Oncol_39_1Clozapine Improves Behavioral and Biochemical Outcomes in a MK-801-Induced Mouse Model of Schizophrenia
Andre_2020_Foods_9_Effect of Food Preparations on In Vitro Bioactivities and Chemical Components of Fucus vesiculosus
Angelini_2020_Antibiotics.(Basel)_9_Evaluation of Antioxidant, Antimicrobial and Tyrosinase Inhibitory Activities of Extracts from Tricholosporum goniospermum, an Edible Wild Mushroom
Anila_2020_Sci.Total.Environ_765_144268In vivo evaluation of Nano-palladium toxicity on larval stages and adult of zebrafish (Danio rerio)
Annamalai_2020_Anal.Chim.Acta_1135_175Detection of phthalate esters in PET bottled drinks and lake water using esterase/PANI/CNT/CuNP based electrochemical biosensor
Ansari_2020_Curr.Aging.Sci_13_129Nigella sativa L., Supplementary Plant with Anticholinesterase Effect for Cognition Problems: A Kinetic Study
Ansari_2020_Med.Chem_16_155Three Dimensional Quantitative Structure Activity Relationship and Pharmacophore Modeling of Tacrine Derivatives as Acetylcholinesterase Inhibitors in Alzheimer's Treatment
Antonazzo_2020_Minerva.Cardioangiol__Impact of arterial hypertension and its management strategies on cognitive function and dementia: a comprehensive umbrella review
Antunes_2020_Metab.Brain.Dis__Neostigmine treatment induces neuroprotection against oxidative stress in cerebral cortex of asthmatic mice
Anwar_2020_Comput.Biol.Chem_89_107378New naphthalene derivative for cost-effective AChE inhibitors for Alzheimer's treatment: In silico identification, in vitro and in vivo validation
Arabnejad_2020_Chembiochem__Computational design of enantiocomplementary epoxide hydrolases for asymmetric synthesis of aliphatic and aromatic diols
Arafa_2020_Exp.Appl.Acarol__Toxicity, repellency and anti-cholinesterase activities of thymol-eucalyptus combinations against phenotypically resistant Rhipicephalus annulatus ticks
Arafa_2020_Neurotox.Res_37_380Protective Role of Epigallocatechin Gallate in a Rat Model of Cisplatin-Induced Cerebral Inflammation and Oxidative Damage: Impact of Modulating NF-kappaB and Nrf2
Araki_2020_Heliyon_6_e04227Hydrophobic interactions at subsite S1' of human dipeptidyl peptidase IV contribute significantly to the inhibitory effect of tripeptides
Araujo_2020_Mol.Biol.Rep__A novel bacterial carboxylesterase identified in a metagenome derived-clone from Brazilian mangrove sediments
Araujo_2020_Sci.Total.Environ__142899Effects of ultraviolet radiation to Solea senegalensis during early development
Arcanjo_2020_Aquat.Toxicol_219_105384Effects of tritiated water on locomotion of zebrafish larvae: a new insight in tritium toxic effects on a vertebrate model species
Arend_2020_Epilepsy.Behav_112_107346MnSOD Ala16Val polymorphism in cognitive dysfunction in patients with epilepsy: A relationship with oxidative and inflammatory markers
Arends_2020_Cardiol.Res_11_274Heart Rate Changes Following the Administration of Sugammadex to Infants and Children With Comorbid Cardiac, Cardiovascular, and Congenital Heart Diseases
Ariel_2020_Toxicol.Appl.Pharmacol__114963Efficacy of retigabine in ameliorating the brain insult following sarin exposure in the rat
Aries_2020_Minerva.Anestesiol_86_974Ileus in the critically ill: causes, treatment and prevention
Ariza_2020_Clin.Chim.Acta_500_163Genetic variants in the LPL and GPIHBP1 genes, in patients with severe hypertriglyceridaemia, detected with high resolution melting analysis
Armijos_2020_J.Ethnopharmacol__113162Chemical composition and selective BuChE inhibitory activity of the essential oils from aromatic plants used to prepare the traditional Ecuadorian beverage horchata lojana
Armstrong_2020_JAMA_323_548Diagnosis and Treatment of Parkinson Disease: A Review
Arnold_2020_J.Comp.Neurol_528_1754Candidates for photic entrainment pathways to the circadian clock via optic lobe neuropils in the Madeira cockroach
Aroniadou-Anderjaska_2020_Neuropharmacol__108298Acetylcholinesterase inhibitors (nerve agents) as weapons of mass destruction: History, mechanisms of action, and medical countermeasures
Arora_2020_Nat.Prod.Res__1Bacosides enrichment does not improve the anti-amnesic effect of Bacopa monnieri: behavioural and biochemical evidences
Arora_2020_SAR.QSAR.Environ.Res__1In silico guided designing of 4-(1H-benzo[d]imidazol-2-yl)phenol-based mutual-prodrugs of NSAIDs: synthesis and biological evaluation
Arriaga-Guerrero_2020_BMC.Microbiol_20_132LipF increases rifampicin and streptomycin sensitivity in a Mycobacterium tuberculosis surrogate
Arslan_2020_Dalton.Trans_49_203Design, synthesis, characterization of peripherally tetra-pyridine-triazole-substituted phthalocyanines and their inhibitory effects on cholinesterases (AChE/BChE) and carbonic anhydrases (hCA I, II and IX)
Arslan_2020_Int.J.Neurosci__1In vitro neuroprotective effects of farnesene sesquiterpene on alzheimer's disease model of differentiated neuroblastoma cell line
Ashafaq_2020_Drug.Chem.Toxicol__1Role of cinnamon oil against acetaminophen overdose induced neurological aberrations through brain stress and cytokine upregulation in rat brain
Aso_2020_Am.J.Med.Sci_360_261Teneligliptin, a DPP-4 Inhibitor, Decreases Plasma Levels of Inflammatory Chemokines During a Standard Meal Test in Patients With Type 2 Diabetes
Ataei_2020_Indian.J.Clin.Biochem_35_339Therapeutic Potential of Dihydropyridine Calcium Channel Blockers on Oxidative Injury Caused by Organophosphates in Cortex and Cerebellum: An In Vivo Study
Atali_2020_FEBS.Open.Bio_10_2805Interaction of amyloid beta with humanin and acetylcholinesterase is modulated by ATP
Atama_2020_Drug.Chem.Toxicol__1Neuromodulatory and oxidative stress evaluations in African catfish Clarias gariepinus exposed to antipsychotic drug chlorpromazine
Atoyebi_2020_Parasit.Vectors_13_423Investigating the molecular basis of multiple insecticide resistance in a major malaria vector Anopheles funestus (sensu stricto) from Akaka-Remo, Ogun State, Nigeria
Audira_2020_Biomolecules_10_Evaluation of the Adverse Effects of Chronic Exposure to Donepezil (An Acetylcholinesterase Inhibitor) in Adult Zebrafish by Behavioral and Biochemical Assessments
Augustin_2020_ACS.Omega_5_1616Discovery of Helminthosporin, an Anthraquinone Isolated from Rumex abyssinicus Jacq as a Dual Cholinesterase Inhibitor
Aung_2020_Nat.Prod.Bioprospect_10_337Chemical Constituents from the Whole Plant of Cuscuta reflexa
Aupperle-Lellbach_2020_J.Vet.Intern.Med__Histopathological findings and canine pancreatic lipase immunoreactivity in normal dogs and dogs with inflammatory and neoplastic diseases of the pancreas
Avram_2020_Curr.Neuropharmacol_18_696Potential Therapeutic Approaches to Alzheimer's Disease By Bioinformatics, Cheminformatics And Predicted Adme-Tox Tools
Awad_2020_ACS.Omega_5_12081Design and Evaluation of a Co-Mo-Supported Nano Alumina Ultradeep Hydrodesulfurization Catalyst for Production of Environmentally Friendly Diesel Fuel in a Trickle Bed Reactor
Awogbindin_2020_Environ.Toxicol.Pharmacol_78_103412Nigral and ventral tegmental area lesioning induces testicular and sperm morphological abnormalities in a rotenone model of Parkinson's disease
Aydin_2020_Z.Naturforsch.C.J.Biosci_75_153Secondary metabolites of Helichrysum plicatum DC. subsp. plicatum flowers as strong carbonic anhydrase, cholinesterase and alpha-glycosidase inhibitors
Aylanc_2020_J.Food.Biochem__e13463In vitro studies on different extracts of fenugreek (Trigonella spruneriana BOISS.): Phytochemical profile, antioxidant activity, and enzyme inhibition potential
Azadniya_2020_Anal.Chim.Acta_1129_76New incorporation of the S9 metabolizing system into methods for detecting acetylcholinesterase inhibition
Aziz_2020_Environ.Toxicol.Pharmacol__103500Enzymatic and non-enzymatic detoxification in Lycosa terrestris and Pardosa birmanica exposed to single and binary mixture of Copper and Lead
Azman_2020_Molecules_25_Potential Anti-Acetylcholinesterase Activity of Cassia timorensis DC
Baath_2020_Anal.Biochem__113873A suspension-based assay and comparative detection methods for characterization of polyethylene terephthalate hydrolases
Baath_2020_Chembiochem_22_1627Comparative biochemistry of four polyester (PET) hydrolases
Babkova_2020_Comput.Struct.Biotechnol.J_18_1497Structures of hyperstable ancestral haloalkane dehalogenases show restricted conformational dynamics
Badawi_2020_Iran.J.Basic.Med.Sci_23_1628Bee venom attenuates neurodegeneration and motor impairment and modulates the response to L-dopa or rasagiline in a mice model of Parkinson's disease
Badawy_2020_J.Environ.Sci.Health.B__1Optimization of reaction time for detection of organophosphorus pesticides by enzymatic inhibition assay and mathematical modeling of enzyme inhibition
Badr_2020_Environ.Sci.Pollut.Res.Int__Organophosphate toxicity: updates of malathion potential toxic effects in mammals and potential treatments
Baek_2020_Prev.Nutr.Food.Sci_25_389Protein Hydrolysate of Silkworm Pupa Prevents Memory Impairment Induced by Oxidative Stress in Scopolamine-Induced Mice via Modulating the Cholinergic Nervous System and Antioxidant Defense System
Bagri_2020_Mini.Rev.Med.Chem_20_1403Computational Studies on Acetylcholinesterase Inhibitors: From Biochemistry to Chemistry
Bai_2020_Appl.Environ.Microbiol__Functional characterization of Vib-PT, an aromatic prenyltransferase involved in the biosynthesis of vibralactone from Stereum vibrans
Bailey_2020_Nat.Commun_11_4046ABHD11 maintains 2-oxoglutarate metabolism by preserving functional lipoylation of the 2-oxoglutarate dehydrogenase complex
Baker_2020_ACS.Pharmacol.Transl.Sci_3_737Using Esterase Selectivity to Determine the In Vivo Duration of Systemic Availability and Abolish Systemic Side Effects of Topical beta-Blockers
Bakir_2020_J.Food.Biochem__e13350A GC-MS method validation for quantitative investigation of some chemical markers in Salvia hypargeia Fisch. & C.A. Mey. of Turkey: Enzyme inhibitory potential of ferruginol
Bakker_2020_Alzheimers.Dement.(N.Y)_6_e12093Safety, pharmacokinetics, and pharmacodynamics of Gln-1062, a prodrug of galantamine
Bakkes_2020_Plasmid_112_102540Improved pEKEx2-derived expression vectors for tightly controlled production of recombinant proteins in Corynebacterium glutamicum
Baldissera_2020_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__108871Behavioral impairment and neurotoxic responses of silver catfish Rhamdia quelen exposed to organophosphate pesticide trichlorfon: Protective effects of diet containing rutin
Ballard_2020_Curr.Neurol.Neurosci.Rep_20_57Psychosis in Alzheimer's Disease
Ballesteros_2020_Aquat.Toxicol_228_105618What types of enzyme activities are useful biomarkers of bifenthrin exposure on Chironomus sp. (Diptera, Chironomidae) larvae under laboratory and field-based microcosm conditions?
Ballinas-Casarrubias_2020_Polymers.(Basel)_12_Chemical Characterization and Enzymatic Control of Stickies in Kraft Paper Production
Ban_2020_Int.Neurourol.J_24_S48Effect of Glycyrrhizic Acid on Scopolamine-Induced Cognitive Impairment in Mice
Banach_2020_Bioinformation_16_21Identification of tunnels as in potato hydrolases
Banaee_2020_Ecotoxicology__Combined effects of exposure to sub-lethal concentration of the insecticide chlorpyrifos and the herbicide glyphosate on the biochemical changes in the freshwater crayfish Pontastacus leptodactylus
Bani_2020_Sci.Rep_10_19419Single nucleotide polymorphisms in LCAT may contribute to dyslipidaemia in HIV-infected individuals on HAART in a Ghanaian population
Bankaitis_2020_Trends.Cell.Biol__Lipoprotein Lipase Sorting: Sphingomyelin and a Proteoglycan Show the Way
Bao_2020_BMC.Genomics_21_355The seasonal development dynamics of the yak hair cycle transcriptome
Barakat_2020_Molecules_25_Synthesis of a New Class of Spirooxindole-Benzo[b]Thiophene-Based Molecules as Acetylcholinesterase Inhibitors
Baranowska-Wojcik_2020_Nutrients_12_Regardless of the Brewing Conditions, Various Types of Tea are a Source of Acetylcholinesterase Inhibitors
Baranowska-Wojcik_2020_Plant.Foods.Hum.Nutr__Honey as the Potential Natural Source of Cholinesterase Inhibitors in Alzheimer's Disease
Barbeau_2020_Stem.Cell.Res_49_102106Generation of a human induced pluripotent stem cell line (iPSC) from peripheral blood mononuclear cells of a patient with a myasthenic syndrome due to mutation in COLQ
Barbosa_2020_Environ.Toxicol.Pharmacol_77_103377Antioxidative and neurotoxicity effects of acute and chronic exposure of the estuarine polychaete Hediste diversicolor to paracetamol
Barbosa_2020_Food.Chem_333_127456In vitro multifunctionality of phlorotannin extracts from edible Fucus species on targets underpinning neurodegeneration
Barbosa_2020_Pharmaceuticals.(Basel)_13_Repeated Administration of Clinical Doses of Tramadol and Tapentadol Causes Hepato- and Nephrotoxic Effects in Wistar Rats
Barchetta_2020_Int.J.Mol.Sci_21_Angiopoietin-Like Protein 4 Overexpression in Visceral Adipose Tissue from Obese Subjects with Impaired Glucose Metabolism and Relationship with Lipoprotein Lipase
Barchuk_2020_Clin.Chim.Acta_510_423The antagonic behavior of GPIHBP1 between EAT and circulation does not reflect lipolytic enzymes levels in the tissue and serum from coronary patients
Barfejani_2020_Life.Sci_263_118575Donepezil in the treatment of ischemic stroke: Review and future perspective
Bargar_2020_Arch.Environ.Contam.Toxicol_79_233Mortality and Cholinesterase Inhibition in Butterflies Following Aerial Naled Applications for Mosquito Control on the National Key Deer Refuge
Barka_2020_Environ.Sci.Pollut.Res.Int_27_5670Seasonal ecotoxicological monitoring of freshwater zooplankton in Bir Mcherga dam (Tunisia)
Barker_2020_Neurosci_425_280Screening for Efficacious Anticonvulsants and Neuroprotectants in Delayed Treatment Models of Organophosphate-induced Status Epilepticus
Barlass_2020_Clin.Transl.Gastroenterol_11_e00215Marked Elevation of Lipase in COVID-19 Disease: A Cohort Study
Barnych_2020_Eur.J.Med.Chem_193_112206Development of potent inhibitors of the human microsomal epoxide hydrolase
Barrett_2020_Expert.Rev.Neurother_20_41Therapeutic approaches to cholinergic deficiency in Lewy body diseases
Barrientos_2020_Molecules_25_Chemical Fingerprinting and Biological Evaluation of the Endemic Chilean Fruit Greigia sphacelata (Ruiz and Pav.) Regel (Bromeliaceae) by UHPLC-PDA-Orbitrap-Mass Spectrometry
Bartels_2020_J.Alzheimers.Dis_78_1137Use of Cerebrospinal Fluid Biomarkers of Alzheimer's Disease Risk in Mild Cognitive Impairment and Subjective Cognitive Decline in Routine Clinical Care in Germany
Barthold_2020_J.Alzheimers.Dis_76_579Pharmaceutical Treatment for Alzheimer's Disease and Related Dementias: Utilization and Disparities
Basagni_2020_ChemMedChem_15_1374Functionalized Cannabinoid Subtype 2 Receptor Ligands: Fluorescent, PET, Photochromic and Covalent Molecular Probes
Basit_2020_Mol.Pharm_17_4114Characterization of Differential Tissue Abundance of Major Non-CYP Enzymes in Human
Baskar_2020_Heliyon_6_e05331Larvicidal and histopathology effect of endophytic fungal extracts of Aspergillus tamarii against Aedes aegypti and Culex quinquefasciatus
Bassendine_2020_J.Diabetes__Covid-19 and co-morbidities: a role for Dipeptidyl Peptidase 4 (DPP4) in disease severity?
Bastarache_2020_Insects_11_Transcriptomics-Based Approach Identifies Spinosad-Associated Targets in the Colorado Potato Beetle, Leptinotarsa decemlineata
Bastos_2020_Neuromuscul.Disord__A late-onset congenital myasthenic syndrome due to a heterozygous DOK7 mutation
Basu_2020_Curr.Opin.Lipidol__Regulation of lipoprotein lipase-mediated lipolysis of triglycerides
Batiha_2020_Foods_9_The Pharmacological Activity, Biochemical Properties, and Pharmacokinetics of the Major Natural Polyphenolic Flavonoid: Quercetin
Bauer_2020_FEBS.J_287_1035The modular structure of alpha/beta-hydrolases
Bauer_2020_Int.J.Technol.Assess.Health.Care__1Valuing Alzheimer's disease drugs: a health technology assessment perspective on outcomes
Bautista-Aguilera_2020_Int.J.Mol.Sci_21_Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer's Disease Therapy
Bavandi_2020_Bioorg.Chem_103_104139Porcine pancreas lipase as a green catalyst for synthesis of bis-4-hydroxy coumarins
Beach_2020_Redox.Biol_36_101640Targeting succinate dehydrogenase with malonate ester prodrugs decreases renal ischemia reperfusion injury
Becerra-Amezcua_2020_Environ.Toxicol.Pharmacol_77_103359Effect of pterois volitans (lionfish) venom on cholinergic and dopaminergic systems
Behl_2020_Biomedicines_8_Exploring the Multifaceted Therapeutic Potential of Withaferin A and Its Derivatives
Bell_2020_Subst.Abus__1Donepezil and cognitive remediation therapy to augment treatment of alcohol use disorder related mild cognitive impairment (AUD-MCI): An open label pilot study with historical controls
Bellozi_2020_Neurol.Sci_41_451New multifunctional AChE inhibitor drug prototypes protect against Abeta-induced memory deficit
Ben Ali_2020_Mar.Drugs_18_Characterization of the CAZy Repertoire from the Marine-Derived Fungus Stemphylium lucomagnoense in Relation to Saline Conditions
Ben Othmene_2020_Food.Chem.Toxicol__111134Tebuconazole induced cardiotoxicity in male adult rat
Ben Rejeb_2020_Chem.Biodivers__Chemical composition, antioxidant potential and enzymes inhibitory properties of Globe artichoke by-products
Ben-Azu_2020_Brain.Res__146917Repeated psychosocial stress causes glutamic acid decarboxylase isoform-67, oxidative-Nox-2 changes and neuroinflammation in mice: prevention by treatment with a neuroactive flavonoid, morin
Benfeito_2020_Molecules_25_Exploring the Multi-Target Performance of Mitochondriotropic Antioxidants against the Pivotal Alzheimer's Disease Pathophysiological Hallmarks
Bento_2020_Pest.Manag.Sci_76_287Gene silencing by RNAi via oral delivery of dsRNA by bacteria in the South American tomato pinworm, Tuta absoluta
Berg_2020_J.Neurodev.Disord_12_40Translational outcomes relevant to neurodevelopmental disorders following early life exposure of rats to chlorpyrifos
Bertolet_2020_Optom.Vis.Sci_97_377Pseudopartial Third Nerve Palsy as the Presenting Sign of Ocular Myasthenia Gravis
Besler_2020_Eur.J.Heart.Fail__Nutritional status in tricuspid regurgitation: implications of transcatheter repair
Bhardwaj_2020_J.Oleo.Sci_69_467Influence of Culture Conditions on the Production of Extracellular Esterase from Bacillus licheniformis and Its Characterization
Bhatia_2020_Int.J.Neurosci__1Tadalafil ameliorates memory deficits, oxidative stress, endothelial dysfunction and neuropathological changes in rat model of hyperhomocysteinemia induced vascular dementia
Bhatia_2020_Vascul.Pharmacol__106827Ozagrel a thromboxane A2 synthase inhibitor extenuates endothelial dysfunction, oxidative stress and neuroinflammation in rat model of bilateral common carotid artery occlusion induced vascular dementia
Bhatt_2020_Chemosphere_244_125507Esterase is a powerful tool for the biodegradation of pyrethroid insecticides
Bhattacharyya_2020_IUCrJ_7_825The susceptibility of disulfide bonds towards radiation damage may be explained by S---O interactions
Bi_2020_Bioorg.Chem_100_103902Design, synthesis and evaluation of novel nonquaternary and 3 non-oxime reactivators for acetylcholinesterase inhibited by organophosphates
Biberoglu_2020_Anal.Biochem__113718Characteristic fragment ions associated with dansyl cadaverine and biotin cadaverine adducts on glutamine
Biberoglu_2020_Molecules_25_Chlorpyrifos Oxon-Induced Isopeptide Bond Formation in Human Butyrylcholinesterase
Bilginer_2020_Arch.Pharm.(Weinheim)__e2000243Synthesis and in silico studies of triazene-substituted sulfamerazine derivatives as acetylcholinesterase and carbonic anhydrases inhibitors
Biliktu_2020_Inflammopharmacology__Pharmacological inhibition of soluble epoxide hydrolase attenuates chronic experimental autoimmune encephalomyelitis by modulating inflammatory and anti-inflammatory pathways in an inflammasome-dependent and -independent manner
Billet_2020_Ecotoxicology_29_1476Pesticide tolerance induced by a generalized stress response in wood frogs (Rana sylvatica)
Billot_2020_J.Biol.Chem_295_12993Engineering acyl-homoserine lactone-interfering enzymes toward bacterial control
Bilousova_2020_ACS.Chem.Biol__Dual Neutral Sphingomyelinase-2/Acetylcholinesterase Inhibitors for the treatment of Alzheimer's disease
Biscussi_2020_CNS.Neurol.Disord.Drug.Targets_19_630Design and Microwave-Assisted Synthesis of Aza-Resveratrol Analogs with Potent Cholinesterase Inhibition
Biswas_2020_Chemosphere_270_129438Adaptive mechanisms induced by sparingly soluble mercury sulfide (HgS) in zebrafish: Behavioural and proteomics analysis
Blackstone_2020_Cureus_12_e11739Physostigmine in Anticholinergic Poisoning: An Old Antidote With Resurgence
Blaikie_2020_Bioorg.Med.Chem.Lett__127505Synthesis and in vitro evaluation of vanillin derivatives as multi-target therapeutics for the treatment of Alzheimer's disease
Blaszczak_2020_Food.Chem_314_126181Polyphenols and inhibitory effects of crude and purified extracts from tomato varieties on the formation of advanced glycation end products and the activity of angiotensin-converting and acetylcholinesterase enzymes
Blaszczak_2020_Food.Chem__128421The impact of high-pressure processing on the polyphenol profile and anti-glycaemic, anti-hypertensive and anti-cholinergic activities of extracts obtained from kiwiberry (Actinidia arguta) fruits
Blumer_2020_Invest.Ophthalmol.Vis.Sci_61_31Palisade Endings Have an Exocytotic Machinery But Lack Acetylcholine Receptors and Distinct Acetylcholinesterase Activity
Boaretto_2020_J.Musculoskelet.Neuronal.Interact_20_570Alterations in neuromuscular junctions and oxidative stress of the soleus muscle of obese Wistar rats caused by vibratory platform training
Boaventura_2020_Insects_11_Monitoring of Target-Site Mutations Conferring Insecticide Resistance in Spodoptera frugiperda
Boer_2020_Peptides_136_170457Pharmacokinetics of exogenous GIP(1-42) in C57Bl/6 mice; Extremely rapid degradation but marked variation between available assays
Bogari_2020_Saudi.J.Biol.Sci_27_2018Association between HindIII (rs320) variant in the lipoprotein lipase gene and the presence of coronary artery disease and stroke among the Saudi population
Bogdanovic_2020_Lakartidningen_117_[Alzheimer's disease - the most common cause of dementia]
Bohnert_2020_Toxicol.Lett__Comparative Pharmacokinetics of Three Oximes in a Guinea Pig Model and Efficacy of Combined Oxime Therapy
Boiangiu_2020_Antioxidants.(Basel)_9_Cotinine and 6-Hydroxy-L-Nicotine Reverses Memory Deficits and Reduces Oxidative Stress in Abeta(25-35)-Induced Rat Model of Alzheimer's Disease
Boiangiu_2020_Molecules_25_Cognitive Facilitation and Antioxidant Effects of an Essential Oil Mix on Scopolamine-Induced Amnesia in Rats: Molecular Modeling of In Vitro and In Vivo Approaches
Boiarski_2020_Ecotoxicology__Assessment of antioxidant system, cholinesterase activity and histopathology in Lithobates catesbeianus tadpoles exposed to water from an urban stream
Boll_2020_Environ.Microbiol.Rep_12_3Microbial degradation of phthalates: biochemistry and environmental implications
Bollinger_2020_Appl.Environ.Microbiol_86_e00106Organic-Solvent-Tolerant Carboxylic Ester Hydrolases for Organic Synthesis
Bollinger_2020_Front.Microbiol_11_114A Novel Polyester Hydrolase From the Marine Bacterium Pseudomonas aestusnigri - Structural and Functional Insights
Bollinger_2020_Microb.Biotechnol_13_19The biotechnological potential of marine bacteria in the novel lineage of Pseudomonas pertucinogena
Bonanno_2020_Neuromuscul.Disord__Severe congenital myasthenic syndrome associated with novel biallelic mutation of the CHRND gene
Bondzic_2020_Eur.J.Pharm.Sci_151_105376A new acetylcholinesterase allosteric site responsible for binding voluminous negatively charged molecules - the role in the mechanism of AChE inhibition
Bondzic_2020_J.Inorg.Biochem_205_110990Aminoalcoholate-driven tetracopper(II) cores as dual acetyl and butyrylcholinesterase inhibitors: Experimental and theoretical elucidation of mechanism of action
Bonifacio_2020_Br.J.Pharmacol_177_2123Preclinical pharmacological evaluation of the fatty acid amide hydrolase inhibitor BIA 10-2474
Bonifacio_2020_Chemosphere_261_127782Integrated ecotoxicological assessment of the complex interactions between chlorpyrifos and glyphosate on a non-target species Cnesterodon decemmaculatus (Jenyns, 1842)
Borase_2020_Environ.Res__110609Enzymatic response of Moina macrocopa to different sized zinc oxide particles: An aquatic metal toxicology study
Borges_2020_Bioprocess.Biosyst.Eng_43_2107Ethyl esters production catalyzed by immobilized lipases is influenced by n-hexane and ter-amyl alcohol as organic solvents
Borges_2020_Front.Immunol_11_707Muscle-Specific Kinase Myasthenia Gravis
Borges_2020_Pestic.Biochem.Physiol_169_104651Modulation of octopaminergic and cholinergic pathways induced by Caatinga tree Manilkara rufula chemical compounds in Nauphoeta cinerea cockroaches
Borioni_2020_J.Comput.Aided.Mol.Des_34_1079An activity prediction model for steroidal and triterpenoidal inhibitors of Acetylcholinesterase enzyme
Bortolami_2020_Eur.J.Med.Chem_198_112350New deferiprone derivatives as multi-functional cholinesterase inhibitors: design, synthesis and in vitro evaluation
Bortolotto_2020_Physiol.Behav__112892Modulation of glutamate levels and Na(+),K(+)-ATPase activity contributes to the chrysin memory recovery in hypothyroidism mice
Bosak_2020_Molecules_25_Interactions of Paraoxonase-1 with Pharmacologically Relevant Carbamates
Botelho_2020_Toxins.(Basel)_12_Ligand-Based Virtual Screening, Molecular Docking, Molecular Dynamics, and MM-PBSA Calculations towards the Identification of Potential Novel Ricin Inhibitors
Boudriga_2020_Molecules_25_Three-Component Access to Functionalized Spiropyrrolidine Heterocyclic Scaffolds and Their Cholinesterase Inhibitory Activity
Bouknight_2020_Biochem.Pharmacol__113980Structural and Kinetic Evidence of Aging after Organophosphate Inhibition of Human Cathepsin A
Bousada_2020_Comput.Biol.Chem_88_107359Tyrosol 1,2,3-triazole analogues as new acetylcholinesterase (AChE) inhibitors
Boy_2020_Bioorg.Chem__104524Synthesis, design, and assessment of novel morpholine-derived Mannich bases as multifunctional agents for the potential enzyme inhibitory properties including docking study
Boyko_2020_PLoS.One_15_e0226838Crystal structure of PMGL2 esterase from the hormone-sensitive lipase family with GCSAG motif around the catalytic serine
Bozbey_2020_Mini.Rev.Med.Chem_20_1042A Series of New Hydrazone Derivatives: Synthesis, Molecular Docking and Anticholinesterase Activity Studies
Braczynski_2020_BMC.Pediatr_20_399Cholinergic innervation and ganglion cell distribution in Hirschsprung's disease
Bradley_2020_Nat.Chem.Biol_16_240Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs
Braillon_2020_J.Am.Geriatr.Soc_68_2411Acetylcholinesterase Inhibitors and Dementia: Over Both Sides of the Atlantic Ocean
Brambley_2020_ACS.Sustainable.Chem.Eng_8_10702Structural Characterization of Sphingomonas sp. KT-1 PahZ1-Catalyzed Biodegradation of Thermally Synthesized Poly(asparticacid)
Breijyeh_2020_Molecules_25_Comprehensive Review on Alzheimer's Disease: Causes and Treatment
Bremer_2020_J.Chem.Inf.Model__Overcoming the Heuristic Nature of k-means Clustering: Identification and Characterization of Binding Modes from Simulations of Molecular Recognition Complexes
Brenet_2020_Sci.Rep_10_19228Organophosphorus diisopropylfluorophosphate (DFP) intoxication in zebrafish larvae causes behavioral defects, neuronal hyperexcitation and neuronal death
Briatore_2020_Front.Mol.Neurosci_13_164Dystroglycan Mediates Clustering of Essential GABAergic Components in Cerebellar Purkinje Cells
Brinza_2020_Antioxidants.(Basel)_9_Ameliorative Effects of Rhoifolin in Scopolamine-Induced Amnesic Zebrafish (Danio rerio) Model
Brodeur_2020_Environ.Sci.Pollut.Res.Int__Biomarker and hematological fieldwork with amphibians: is it necessary to sample all night?
Brown_2020_J.Pharmacol.Exp.Ther__Dorsoventral-specific effects of a sarin surrogate, diisopropylfluorophosphate, on synaptic transmission in the mouse hippocampus
Bruce_2020_Int.J.Mol.Sci_21_Genetic Variants of Lipoprotein Lipase and Regulatory Factors Associated with Alzheimer's Disease Risk
Bruce_2020_Metabolites_10_Neuronal Lipoprotein Lipase Deficiency Alters Neuronal Function and Hepatic Metabolism
Bruellman_2020_Thyroid__Insertion of an Alu Element in Thyroglobulin Gene as a Novel Cause of Congenital Hypothyroidism
Bua_2020_Can.Vet.J_61_743Evaluation of 1,2-o-dilauryl-rac-glycero-3-glutaric acid-(6'-methylresorufin) ester lipase concentrations in cats with kidney disease and with normal SNAP fPL
Bukhari_2020_Eur.Rev.Med.Pharmacol.Sci_24_81431-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU), a soluble epoxide hydrolase inhibitor, lowers L-NAME-induced hypertension through suppression of angiotensin-converting enzyme in rats
Buldurun_2020_J.Biomol.Struct.Dyn__1Synthesis, characterization, powder X-ray diffraction analysis, thermal stability, antioxidant properties and enzyme inhibitions of M(II)-Schiff base ligand complexes
Bun_2020_PLoS.One_15_e0230166Comparative analysis of the human serine hydrolase OVCA2 to the model serine hydrolase homolog FSH1 from S. cerevisiae
Bunsick_2020_Nat.Plants_6_646SMAX1-dependent seed germination bypasses GA signalling in Arabidopsis and Striga
Buralli_2020_Rev.Saude.Publica_54_133Occupational exposure to pesticides and health symptoms among family farmers in Brazil
Burcul_2020_Curr.Med.Chem_27_4297Terpenes, Phenylpropanoids, Sulfur and Other Essential Oil Constituents as Inhibitors of Cholinesterases
Burger_2020_Plant.Direct_4_e00263In-silico analysis of the strigolactone ligand-receptor system
Burger_2020_Trends.Plant.Sci_25_395The Many Models of Strigolactone Signaling
Burilova_2020_Nanoscale_12_13757Bi-functional sterically hindered phenol lipid-based delivery systems as potential multi-target agents against Alzheimer's disease via an intranasal route
Burmistrov_2020_Bioorg.Med.Chem.Lett_30_126908Imidazolidine-2,4,5- and pirimidine-2,4,6-triones - New primary pharmacophore for soluble epoxide hydrolase inhibitors with enhanced water solubility
Burmistrov_2020_Bioorg.Med.Chem.Lett_30_127430Bioisosteric substitution of adamantane with bicyclic lipophilic groups improves water solubility of human soluble epoxide hydrolase inhibitors
Burrows_2020_Pharmacol.Biochem.Behav_195_172955Environmental enrichment modulates affiliative and aggressive social behaviour in the neuroligin-3 R451C mouse model of autism spectrum disorder
Buruaga-Ramiro_2020_Enzyme.Microb.Technol_139_109590Unexplored lipolytic activity of Escherichia coli: Implications for lipase cloning
Butler_2020_ACS.Infect.Dis_6_2994Resistance to Some But Not Other Dimeric Lindenane Sesquiterpenoid Esters Is Mediated by Mutations in a Plasmodium falciparum Esterase
Buzyurova_2020_Toxicology__152578Surface modification of pralidoxime chloride-loaded solid lipid nanoparticles for enhanced brain reactivation of organophosphorus-inhibited AChE: pharmacokinetics in rat
Byrne_2020_J.Vis_20_5Transient cholinergic enhancement does not significantly affect either the magnitude or selectivity of perceptual learning of visual texture discrimination
Cacabelos_2020_Expert.Opin.Drug.Metab.Toxicol_16_673Pharmacogenetic considerations when prescribing cholinesterase inhibitors for the treatment of Alzheimer's disease
Cacciotti_2020_Mater.Sci.Eng.C.Mater.Biol.Appl_111_110744Reusable optical multi-plate sensing system for pesticide detection by using electrospun membranes as smart support for acetylcholinesterase immobilisation
Caceres-Wenzel_2020_Environ.Sci.Pollut.Res.Int__Combined effects of goethite nanoparticles with metallic contaminants and an organophosphorus pesticide on Eisenia andrei
Cadez_2020_Molecules_25_Benzobicyclo[3.2.1]octene Derivatives as a New Class of Cholinesterase Inhibitors
Caetano-Silva_2020_J.Agric.Food.Chem_68_12433Isolation and Sequencing of Cu-, Fe-, and Zn-Binding Whey Peptides for Potential Neuroprotective Applications as Multitargeted Compounds
Cahlikova_2020_Molecules_25_Chemistry and Biological Activity of Alkaloids from the Genus Lycoris (Amaryllidaceae)
Cai_2020_Angew.Chem.Int.Ed.Engl__Enzyme-Triggered Disassembly of Perylene Monoimide-based Nanoclusters for Activatable and Deep Photodynamic Therapy
Cai_2020_BMC.Biotechnol_20_36Functional expression of a novel methanol-stable esterase from Geobacillus subterraneus DSM13552 for biocatalytic synthesis of cinnamyl acetate in a solvent-free system
Cai_2020_Fish.Physiol.Biochem_46_187Cadmium exposure affects growth performance, energy metabolism, and neuropeptide expression in Carassius auratus gibelio
Cai_2020_Pestic.Biochem.Physiol_162_23Correlation between CYP1A1 polymorphisms and susceptibility to glyphosate-induced reduction of serum cholinesterase: A case-control study of a Chinese population
Cai_2020_Plant.Biotechnol.J_18_814Genome sequencing of the Australian wild diploid species Gossypium australe highlights disease resistance and delayed gland morphogenesis
Calas_2020_Biomolecules_10_Efficacy Assessment of an Uncharged Reactivator of NOP-Inhibited Acetylcholinesterase Based on Tetrahydroacridine Pyridine-Aldoxime Hybrid in Mouse Compared to Pralidoxime
Calfio_2020_J.Alzheimers.Dis_77_33The Emerging Role of Nutraceuticals and Phytochemicals in the Prevention and Treatment of Alzheimer's Disease
Camarillo-Lopez_2020_Molecules_25_Tert-butyl-(4-hydroxy-3-((3-(2-methylpiperidin-yl)propyl)carbamoyl)phenyl)carbamate Has Moderated Protective Activity in Astrocytes Stimulated with Amyloid Beta 1-42 and in a Scopolamine Model
Campagna_2020_Antioxidants.(Basel)_9_Paraoxonase-2 Silencing Enhances Sensitivity of A375 Melanoma Cells to Treatment with Cisplatin
Campello_2020_Parasitol.Int__102066Correlation of plasma butyrylcholinesterase concentration with Acethylcholinesterase H353N polymorphism in the inflammatory response of Chagas disease patients
Campoy_2020_Genome.Biol_21_306Gamete binning: chromosome-level and haplotype-resolved genome assembly enabled by high-throughput single-cell sequencing of gamete genomes
Can_2020_Neuropsychiatr.Dis.Treat_16_3251Missense Genetic Polymorphisms of Microsomal (EPHX1) and Soluble Epoxide Hydrolase (EPHX2) and Their Relation to the Risk of Large Artery Atherosclerotic Ischemic Stroke in a Turkish Population
Cao_2020_Cancers.(Basel)_12_N-MYC Downstream Regulated Gene 4 (NDRG4), a Frequent Downregulated Gene through DNA Hypermethylation, plays a Tumor Suppressive Role in Esophageal Adenocarcinoma
Cao_2020_Colloids.Surf.B.Biointerfaces_189_110874PEI-crosslinked lipase on the surface of magnetic microspheres and its characteristics
Cao_2020_J.Agric.Food.Chem_68_7298An Overview on the Mechanisms and Applications of Enzyme Inhibition-Based Methods for Determination of Organophosphate and Carbamate Pesticides
Cao_2020_Nat.Commun_11_3744Neuroligin 2 regulates absence seizures and behavioral arrests through GABAergic transmission within the thalamocortical circuitry
Cao_2020_Phytochemistry_177_112449Mexicanolide-type limonoids from the twigs and leaves of Cipadessa baccifera
Cao_2020_Toxicol.Lett__Effect of superabsorbent polymers (SAP) and metal organic frameworks (MOF) wiping sandwich patch on human skin decontamination and detoxification in vitro
Capatina_2020_Antioxidants.(Basel)_9_1083Thymus vulgaris Essential Oil Protects Zebrafish against Cognitive Dysfunction by Regulating Cholinergic and Antioxidants Systems
Capatina_2020_Antioxidants.(Basel)_9_62Rosmarinus officinalis Essential Oil Improves Scopolamine-Induced Neurobehavioral Changes via Restoration of Cholinergic Function and Brain Antioxidant Status in Zebrafish (Danio rerio)
Caputi_2020_Nat.Chem.Biol_16_383Structural basis of cycloaddition in biosynthesis of iboga and aspidosperma alkaloids
Caratelli_2020_Biosens.Bioelectron_165_112411Precision medicine in Alzheimer's disease: An origami paper-based electrochemical device for cholinesterase inhibitors
Carbaugh_2020_J.Appl.Toxicol__Assessment of zebrafish embryo photomotor response sensitivity and phase-specific patterns following acute- and long-duration exposure to neurotoxic chemicals and chemical weapon precursors
Carbonnel_2020_PLoS.Genet_16_e1009249Lotus japonicus karrikin receptors display divergent ligand-binding specificities and organ-dependent redundancy
Carbonnel_2020_Plant.Signal.Behav__1840852MAX2-independent transcriptional responses to rac-GR24 in Lotus japonicus roots
Carbonnel_2020_Proc.Natl.Acad.Sci.U.S.A_117_21757The karrikin signaling regulator SMAX1 controls Lotus japonicus root and root hair development by suppressing ethylene biosynthesis
Cardoso_2020_Vet.Parasitol_280_109090Terpenes on Rhipicephalus (Boophilus) microplus: Acaricidal activity and acetylcholinesterase inhibition
Carikci_2020_Z.Naturforsch.C.J.Biosci_75_271Composition of the essential oil of Satureja metastasiantha: a new species for the flora of Turkey
Carlos_2020_Nutr.Neurosci__1Cognitive improvements in a rat model with polyunsaturated fatty acids EPA and DHA through alpha7-nicotinic acetylcholine receptors
Carlsson_2020_Aliment.Pharmacol.Ther_51_1305Review article: the emerging role of genetics in precision medicine for patients with non-alcoholic steatohepatitis
Carr_2020_Front.Microbiol_11_571265Microbial Polyethylene Terephthalate Hydrolases: Current and Future Perspectives
Carvalho_2020_ACS.Chem.Biol_15_8783-Oxo-beta-sultam as a Sulfonylating Chemotype for Inhibition of Serine Hydrolases and Activity-Based Protein Profiling
Carvalho_2020_Ecotoxicol.Environ.Saf_196_110560Biomarkers of the oxidative stress and neurotoxicity in tissues of the bullfrog, Lithobates catesbeianus to assess exposure to metals
Casajus_2020_Biomacromolecules_21_2874Lipase-Catalyzed Ring-Opening Polymerization of Benzyl Malolactonate: An Unusual Mechanism?
Cascella_2020_World.J.Clin.Cases_8_245Awareness during emergence from anesthesia: Features and future research directions
Cassidy_2020_Hum.Mutat_41_1967Single nucleotide polymorphisms in CEL-HYB1 increase risk for chronic pancreatitis through proteotoxic misfolding
Castaneda-Loaiza_2020_Nat.Prod.Res__1In vitro enzyme inhibitory and anti-oxidant properties, cytotoxicity and chemical composition of the halophyte Malcolmia littorea (L.) R.Br. (Brassicaceae)
Castelli_2020_J.Med.Chem_63_1261Benzisothiazolinone derivatives as potent allosteric monoacylglycerol lipase inhibitors that functionally mimic sulfenylation of regulatory cysteines
Castilhos_2020_Exp.Gerontol__111016Uncaria tomentosa improves cognition, memory and learning in middle-aged rats
Cattel_2020_Evol.Appl__A genomic amplification affecting a carboxylesterase gene cluster confers organophosphate resistance in the mosquito Aedes aegypti: From genomic characterization to high-throughput field detection
Catto_2020_ACS.Med.Chem.Lett_11_869Chiral Separation, X-ray Structure, and Biological Evaluation of a Potent and Reversible Dual Binding Site AChE Inhibitor
Cavalcante_2020_Biomolecules_10_Acetylcholinesterase: The Hub for Neurodegenerative Diseases and Chemical Weapons Convention
Cavalcante_2020_Life.Sci__117915Acetylcholinesterase inhibition prevents alterations in cardiovascular autonomic control and gastric motility in L-NAME-induced hypertensive rats
Cazarin_2020_Behav.Brain.Res__112945Usnic acid enantiomers restore cognitive deficits and neurochemical alterations induced by Abeta(1-42) in mice
Celebioglu_2020_J.Biomol.Struct.Dyn__1Cytotoxic effects, carbonic anhydrase isoenzymes, alpha-glycosidase and acetylcholinesterase inhibitory properties, and molecular docking studies of heteroatom-containing sulfonyl hydrazone derivatives
Celik_2020_Bioorg.Chem_107_104606Synthesis of novel 1,2,3 triazole derivatives and assessment of their potential cholinesterases, glutathione S-transferase enzymes inhibitory properties: An in vitro and in silico study
Celik_2020_Mol.Biol.Rep__Neuroprotective effect of rutin against colistin-induced oxidative stress, inflammation and apoptosis in rat brain associated with the CREB/BDNF expressions
Cerezer_2020_Ecotoxicol.Environ.Saf_203_110982Influence of pesticides and abiotic conditions on biochemical biomarkers in Aegla aff. longirostri (crustacea, anomura): Implications for conservation
Cerezer_2020_Environ.Sci.Pollut.Res.Int_27_45349Raising the water temperature: consequences in behavior and biochemical biomarkers of the freshwater crab Aegla longirostri (Crustacea, Anomura)
Cestonaro_2020_Environ.Sci.Pollut.Res.Int__Biochemical, hematological and immunological parameters and relationship with occupational exposure to pesticides and metals
Cevikelli-Yakut_2020_J.Physiol.Pharmacol_71_Myrtus communis improves cognitive impairment in renovascular hypertensive rats
Chabchoub_2020_J.Pediatr.Hematol.Oncol_42_310Hemophagocytic Lymphohistiocytosis: A Rare Complication of an Ultrarare Lysosomal Storage Disease
Chainoglou_2020_Molecules_25_Hybridization of Curcumin Analogues with Cinnamic Acid Derivatives as Multi-Target Agents Against Alzheimer's Disease Targets
Chakravarty_2020_Drug.Dev.Res_81_242Dual targeting of cholinesterase and amyloid beta with pyridinium/isoquinolium derivatives
Chambers_2020_Ann.N.Y.Acad.Sci__Central neuroprotection demonstrated by novel oxime countermeasures to nerve agent surrogates
Chambers_2020_Neuropharmacol__108201Oxime-mediated reactivation of organophosphate-inhibited acetylcholinesterase with emphasis on centrally-active oximes
Chan_2020_Australas.J.Dermatol_61_e417Re-pigmentation of hair after prolonged cholinesterase inhibitor therapy in a Chinese population
Chan_2020_J.Antimicrob.Chemother_75_2760AbGRI4, a novel antibiotic resistance island in multiply antibiotic-resistant Acinetobacter baumannii clinical isolates
Chandra_2020_Microb.Cell.Fact_19_169Microbial lipases and their industrial applications: a comprehensive review
Chang_2020_Environ.Sci.Pollut.Res.Int_27_7280Toxicity assessment of municipal sewage treatment plant effluent by an integrated biomarker response in the liver of crucian carp (Carassius auratus)
Chang_2020_Environ.Toxicol_35_1326Comparative assessment of neurotoxicity impacts induced by alkyl tri-n-butyl phosphate and aromatic tricresyl phosphate in PC12 cells
Chang_2020_J.Biomed.Mater.Res.B.Appl.Biomater_108_2088Cytotoxicity and genotoxicity of DMABEE, a co-photoinitiator of resin polymerization, on CHO-K1 cells: Role of redox and carboxylesterase
Chang_2020_Neurobiol.Learn.Mem__107154Modulation of the MAPKs pathways affects Abeta-induced cognitive deficits in Alzheimer's disease via activation of alpha7nAChR
Chansi_2020_Nanoscale_12_21719Metal Organic Framework steered electrosynthesis of anisotropic gold nanorods for specific sensing of organophosphate pesticides in vegetables collected from the field
Chanteux_2020_Drug.Metab.Dispos_48_778Application of Azamulin to Determine the Contribution of CYP3A4/5 to Drug Metabolic Clearance Using Human Hepatocytes
Chaves_2020_Cell.Mol.Biol.(Noisy-le-grand)_66_54Palmatine antioxidant and anti-acetylcholinesterase activities: A pre-clinical assessment
Chaves_2020_Int.J.Biol.Macromol__Biological evaluation of BF2-naphthyridine compounds: Tyrosinase and acetylcholinesterase activity, CT-DNA and HSA binding property evaluations
Chaves_2020_Molecules_25_Design, Synthesis, and In Vitro Evaluation of Hydroxybenzimidazole-Donepezil Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease
Chek_2020_iScience_23_101084Asymmetric Open-Closed Dimer Mechanism of Polyhydroxyalkanoate Synthase PhaC
Chen_2020_3.Biotech_10_160Genome analysis of cellulose and hemicellulose degrading Micromonospora sp. CP22
Chen_2020_Anal.Biochem__113835Sensitive and reversible perylene derivative-based fluorescent probe for acetylcholinesterase activity monitoring and its inhibitor
Chen_2020_Anal.Chim.Acta_1111_8Thiol inhibition of Hg cold vapor generation in SnCl2/NaBH4 system: A homogeneous bioassay for H2O2/glucose and butyrylcholinesterase/pesticide sensing by atomic spectrometry
Chen_2020_Appl.Biochem.Biotechnol_191_112Isolation, Expression and Characterization of the Thermophilic Recombinant Esterase from Geobacillus thermodenitrificans PS01
Chen_2020_Appl.Biochem.Biotechnol__Enzymatic Synthesis of beta-Sitosterol Laurate by Candida rugosa Lipase AY30 in the Water/AOT/Isooctane Reverse Micelle
Chen_2020_Biol.Open_9_bio048462FAM172A inhibits EMT in pancreatic cancer via ERK-MAPK signaling
Chen_2020_Biosens.Bioelectron_170_112668Instrument-free and visual detection of organophosphorus pesticide using a smartphone by coupling aggregation-induced emission nanoparticle and two-dimension MnO(2) nanoflake
Chen_2020_Biotechnol.Lett_42_2643Enantioselective synthesis of a chiral intermediate of himbacine analogs by Burkholderia cepacia lipase A
Chen_2020_Brain.Res__146671Aberrant mPFC GABAergic Synaptic Transmission and Fear Behavior in Neuroligin-2 R215H Knock-in Mice
Chen_2020_Ecotoxicol.Environ.Saf_197_110608Toxic effects of different-sized graphene oxide particles on zebrafish embryonic development
Chen_2020_Environ.Int_134_1051932,3,7,8-Tetrachlorodibenzo-p-dioxin and up-regulation of neurofilament expression in neuronal cells: Evaluation of AhR and MAPK pathways
Chen_2020_Environ.Pollut_268_115895Bioconcentration and developmental neurotoxicity of novel brominated flame retardants, hexabromobenzene and pentabromobenzene in zebrafish
Chen_2020_Front.Bioeng.Biotechnol_8_676Molecular Dynamic Simulation of the Porcine Pancreatic Lipase in Non-aqueous Organic Solvents
Chen_2020_Front.Psychiatry_11_564843Enhanced Contextual Fear Memory and Elevated Astroglial Glutamate Synthase Activity in Hippocampal CA1 BChE shRNA Knockdown Mice
Chen_2020_Int.J.Biol.Macromol_154_1314In situ and real-time insight into Rhizopus chinensis lipase under high pressure and temperature: Conformational traits and biobehavioural analysis
Chen_2020_Int.J.Environ.Res.Public.Health_17_Development and Molecular Investigation into the Effects of Carbamazepine Exposure in the Zebrafish (Danio rerio)
Chen_2020_J.Biol.Chem_296_100104ABHD5 suppresses cancer cell anabolism through lipolysis-dependent activation of the AMPK/mTORC1 pathway
Chen_2020_J.Hazard.Mater_409_124974Environmentally relevant concentrations of sertraline disrupts behavior and the brain and liver transcriptome of juvenile yellow catfish (Tachysurus fulvidraco): Implications for the feeding and growth axis
Chen_2020_J.Neurosci_40_818814,15-Epoxyeicosatrienoic Acid Alleviates Pathology in a Mouse Model of Alzheimer's Disease
Chen_2020_Nat.Prod.Res__1Applanaic acids A-C, three new highly oxygenated lanostane triterpenoids from the fruiting bodies of Ganoderma applanatum
Chen_2020_Nat.Rev.Chem_4_114Enzymatic degradation of plant biomass and synthetic polymers
Chen_2020_Neurobiol.Dis__104850Effects of GluN2A and GluN2B gain-of-function epilepsy mutations on synaptic currents mediated by diheteromeric and triheteromeric NMDA receptors
Chen_2020_Pestic.Biochem.Physiol_167_104601The overexpression of three cytochrome P450 genes CYP6CY14, CYP6CY22 and CYP6UN1 contributed to metabolic resistance to dinotefuran in melon/cotton aphid, Aphis gossypii Glover
Chen_2020_Sci.Total.Environ_709_136138Efficient biodegradation of highly crystallized polyethylene terephthalate through cell surface display of bacterial PETase
Chen_2020_Shock_53_761sEH Inhibitor Tppu Ameliorates Cecal Ligation and Puncture-Induced Sepsis by Regulating Macrophage Functions
Cheng_2020_Biotechnol.Rep.(Amst)_27_e00482Industrial enzymes-producing marine bacteria from marine resources
Cheng_2020_Chemosphere_247_125870The immunotoxicity and neurobehavioral toxicity of zebrafish induced by famoxadone-cymoxanil
Cheng_2020_Ecotoxicol.Environ.Saf_187_109848Potential of esterase DmtH in transforming plastic additive dimethyl terephthalate to less toxic mono-methyl terephthalate
Cheng_2020_Ecotoxicol.Environ.Saf_201_110725Effects of lincomycin hydrochloride on the neurotoxicity of zebrafish
Cheraif_2020_Molecules_25_Chemical Composition, Antioxidant, Anti-Tyrosinase, Anti-Cholinesterase and Cytotoxic Activities of Essential Oils of Six Algerian Plants
Chermside-Scabbo_2020_J.Bone.Miner.Res__Old Mice Have Less Transcriptional Activation but Similar Periosteal Cell Proliferation Compared to Young-Adult Mice in Response to In Vivo Mechanical Loading
Chernii_2020_Wiad.Lek_73_857The role of cholinergic insufficiency in cognitive impairment among patients with chronic cerebral ischemia
Chesterfield_2020_ACS.Synth.Biol_9_2107Rational Design of Novel Fluorescent Enzyme Biosensors for Direct Detection of Strigolactones
Chheng_2020_Pharmaceuticals.(Basel)_13_Multitarget Activities of Kleeb Bua Daeng, a Thai Traditional Herbal Formula, Against Alzheimer's Disease
Chiavaroli_2020_Antioxidants.(Basel)_9_Identification of Chemical Profiles and Biological Properties of Rhizophora racemosa G. Mey. Extracts Obtained by Different Methods and Solvents
Chiu_2020_Clin.Neurol.Neurosurg_195_105959Deep cerebral microbleeds are associated with poor cholinesterase inhibitor treatment response in people with Alzheimer disease
Chmelova_2020_Appl.Environ.Microbiol_86_A Haloalkane Dehalogenase from Saccharomonospora viridis Strain DSM 43017, a Compost Bacterium with Unusual Catalytic Residues, Unique (S)-Enantiopreference, and High Thermostability
Cho_2020_Cancer.Res.Treat_52_309Characterization of Oncolytic Vaccinia Virus Harboring the Human IFNB1 and CES2 Transgenes
Cho_2020_Molecules_25_Inhibitory Activity of Quercetin 3-O-Arabinofuranoside and 2-Oxopomolic Acid Derived from Malus domestica on Soluble Epoxide Hydrolase
Cho_2020_Redox.Biol_29_101405Complex interrelationships between nitro-alkene-dependent inhibition of soluble epoxide hydrolase, inflammation and tumor growth
Cho_2020_Sci.Rep_10_21280Discovery of a novel fibroblast activation protein (FAP) inhibitor, BR103354, with anti-diabetic and anti-steatotic effects
Choi_2020_Nat.Commun_11_2114The negative regulator SMAX1 controls mycorrhizal symbiosis and strigolactone biosynthesis in rice
Choubey_2020_Bioorg.Med.Chem_28_115721Design, synthesis, and multitargeted profiling of N-benzylpyrrolidine derivatives for the treatment of Alzheimer's disease
Choudhary_2020_Front.Immunol_11_1664Identification of SARS-CoV-2 Cell Entry Inhibitors by Drug Repurposing Using in silico Structure-Based Virtual Screening Approach
Chouryal_2020_Biomater.Sci_8_6730The nano-bio interactions of rare-earth doped BaF(2) nanophosphors shape the developmental processes of zebrafish
Chowdhury_2020_J.Food.Biochem__e13571Inhibition of BACE1, MAO-B, cholinesterase enzymes, and anti-amyloidogenic potential of selected natural phytoconstituents: Multi-target-directed ligand approach
Chrouda_2020_Toxins.(Basel)_12_An Acetylcholinesterase Inhibition-Based Biosensor for Aflatoxin B1 Detection Using Sodium Alginate as an Immobilization Matrix
Chuang_2020_J.Alzheimers.Dis__Interaction between Apolipoprotein E and Butyrylcholinesterase Genes on Risk of Alzheimer's Disease in a Prospective Cohort Study
Chui_2020_Cell.Rep_33_108264Activation of the CARD8 Inflammasome Requires a Disordered Region
Chukwuekezie_2020_Parasit.Vectors_13_152Resistance status of Anopheles gambiae (s.l.) to four commonly used insecticides for malaria vector control in South-East Nigeria
Chung_2020_Biotechnol.Bioeng_117_157The impact of sialylation linkage-type on the pharmacokinetics of recombinant butyrylcholinesterases
Cieslikiewicz-Bouet_2020_Biochem.Pharmacol__114010Functional characterization of multifunctional ligands targeting acetylcholinesterase and alpha 7 nicotinic acetylcholine receptor
Cipres-Flores_2020_Drug.Dev.Res_81_256Identification of two arylimides as cholinesterase inhibitors and testing of propranolol addition on impaired rat memory
Cipriani_2020_Nat.Prod.Res__1Phenolic compounds of Eugenia involucrata (Myrtaceae) extracts and associated antioxidant and inhibitory effects on acetylcholinesterase and alpha-glucosidase
Cizkova_2020_Cells.Tissues.Organs_208_37HT-29 and Caco2 Cell Lines Are Suitable Models for Studying the Role of Arachidonic Acid-Metabolizing Enzymes in Intestinal Cell Differentiation
Cobilinschi_2020_Rom.J.Morphol.Embryol_61_423Histopathological features of low-dose organophosphate exposure
Codony_2020_J.Med.Chem_63_92372-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Model of Acute Pancreatitis
Cogan_2020_ACS.Chem.Biol_15_2783Structural Basis for Enzymatic Off-Loading of Hybrid Polyketides by Dieckmann Condensation
Collins_2020_AANA.J_88_485Anesthesia and Perioperative Considerations for Patients With Myasthenia Gravis
Colloby_2020_Brain.Commun_2_fcaa098Cholinergic muscarinic M(1)/M(4) receptor networks in dementia with Lewy bodies
Colosimo_2020_Food.Funct_11_10896Mycoprotein ingredient structure reduces lipolysis and binds bile salts during simulated gastrointestinal digestion
Comoletti_2020_Neuropharmacol__108381Comparative mapping of selected structural determinants on the extracellular domains of cholinesterase-like cell-adhesion molecules
Conceicao_2020_Phytochem.Anal__Rapid structural characterisation of benzylisoquinoline and aporphine alkaloids from Ocotea spixiana acaricide extract by HPTLC-DESI-MS(n)
Contreras-Aguilar_2020_Animals.(Basel)_10_Changes in Salivary Analytes of Horses Due to Circadian Rhythm and Season: A Pilot Study
Contreras-Perera_2020_Parasit.Vectors_13_224Impact of deltamethrin selection on kdr mutations and insecticide detoxifying enzymes in Aedes aegypti from Mexico
Conway_2020_Biogerontology__Alzheimer's disease: targeting the glutamatergic system
Cope_2020_Cogn.Affect.Behav.Neurosci_20_1173Converging evidence that short-active photoperiod increases acetylcholine signaling in the hippocampus
Corbin_2020_Biotechnol.Bioeng_117_3053Technoeconomic analysis of semicontinuous bioreactor production of biopharmaceuticals in transgenic rice cell suspension cultures
Cornara_2020_Plants.(Basel)_9_Comparative and Functional Screening of Three Species Traditionally used as Antidepressants: Valeriana officinalis L., Valeriana jatamansi Jones ex Roxb. and Nardostachys jatamansi (D.Don) DC
Cornelius_2020_Anesth.Prog_67_177Pseudocholinesterase Deficiency Considerations: A Case Study
Corni_2020_J.Chromatogr.A_1629_461511Effect-directed analysis of bioactive compounds in Cannabis sativa L. by high-performance thin-layer chromatography
Correa_2020_Metabolites_10_Isolation of Three Lycorine Type Alkaloids from Rhodolirium speciosum (Herb.) Ravenna Using pH-Zone-Refinement Centrifugal Partition Chromatography and Their Acetylcholinesterase Inhibitory Activities
Coscia_2020_Nature__The structure of human thyroglobulin
Cossi_2020_Ecotoxicol.Environ.Saf_192_110248Toxicity evaluation of the active ingredient acetamiprid and a commercial formulation (Assail(R) 70) on the non-target gastropod Biomphalaria straminea (Mollusca: Planorbidae)
Costa_2020_Am.J.Physiol.Gastrointest.Liver.Physiol_318_G99Neural motor complexes propagate continuously along the full length of mouse small intestine and colon
Costa_2020_ChemMedChem__Synthesis, molecular docking and preliminary evaluation of 2-(1,2,3-triazoyl)-benzaldehydes as multifunctional agents for the treatment of Alzheimer's disease
Costa_2020_J.Inorg.Biochem_206_111039Donepezil-based hybrids as multifunctional anti-Alzheimer's disease chelating agents: Effect of positional isomerization
Craig_2020_EFSA.J_18_e06087Cumulative dietary risk characterisation of pesticides that have acute effects on the nervous system
Cranston_2020_Brain.Commun_2_fcaa033Cholinergic and inflammatory phenotypes in transgenic tau mouse models of Alzheimer's disease and frontotemporal lobar degeneration
Cromey_2020_Plant.Dis_104_483Susceptibility of Garden Trees and Shrubs to Armillaria Root Rot
Cruz-Miranda_2020_Mol.Biol.Rep_47_489Identification of a Huperzine A-producing endophytic fungus from Phlegmariurus taxifolius
Cui_2020_Biorxiv__Computational redesign of a PETase for plastic biodegradation by the GRAPE strategy
Cui_2020_Front.Microbiol_11_2204Rv3091, An Extracellular Patatin-Like Phospholipase in Mycobacterium tuberculosis, Prolongs Intracellular Survival of Recombinant Mycolicibacterium smegmatis by Mediating Phagosomal Escape
Cui_2020_Pharmaceutics_12_In-Depth Characterization of EpiIntestinal Microtissue as a Model for Intestinal Drug Absorption and Metabolism in Human
Cullum_2020_Int.J.Geriatr.Psychiatry__Predictors of mortality in Maori, Pacific Island and European patients diagnosed with dementia at a New Zealand Memory Service
Curran_2020_Biochemistry__Structure and Function of BorB, the Type II Thioesterase from the Borrelidin Biosynthetic Gene Cluster
Cuzziol_2020_Chemosphere__128475Toxicity assessment at different experimental scenarios with glyphosate, chlorpyrifos and antibiotics in Rhinella arenarum (Anura: Bufonidae) tadpoles
Czarnecka_2020_Int.J.Mol.Sci_21_New Tetrahydroacridine Hybrids with Dichlorobenzoic Acid Moiety Demonstrating Multifunctional Potential for the Treatment of Alzheimer's Disease
Czernicka_2020_Molecules_25_Acetylcholinesterase Inhibitors among Zingiber officinale Terpenes-Extraction Conditions and Thin Layer Chromatography-Based Bioautography Studies
D'Avila da Silva_2020_Biochimie_168_297Molecular docking and in vitro evaluation of a new hybrid molecule (JM-20) on cholinesterase activity from different sources
Dada_2020_J.Food.Biochem__e13435Extracts from Almond (Terminalia catappa) leaf and stem bark mitigate the activities of crucial enzymes and oxidative stress associated with hypertension in cyclosporine A-stressed rats
Dai_2020_Front.Pediatr_8_451The Anti-inflammatory Effect of Soluble Epoxide Hydrolase Inhibitor and 14, 15-EET in Kawasaki Disease Through PPARgamma/STAT1 Signaling Pathway
Dai_2020_Mar.Drugs_18_Lipopeptide Epimers and a Phthalide Glycerol Ether with AChE Inhibitory Activities from the Marine-Derived Fungus Cochliobolus Lunatus SCSIO41401
Dai_2020_Nat.Prod.Res__1Goodyschle A, a new butenolide with significant BchE inhibitory activity from Goodyera schlechtendaliana
Dai_2020_New.Phytol_226_1104Discovery and characterization of tannase genes in plants: roles in hydrolysis of tannins
Dakieva_2020_Toxicol.Ind.Health_36_591The effect of work environment on the biochemical profile of workers operating at the Ust-Kamenogorsk Titanium and Magnesium Plant
Dalan_2020_Diabetes.Res.Clin.Pract__108216Is DPP4 inhibition a comrade or adversary in COVID-19 Infection
Dalinova_2020_Biomolecules_10_Isolation and Bioactivity of Secondary Metabolites from Solid Culture of the Fungus, Alternaria sonchi
Dall'Acqua_2020_Food.Res.Int_137_109371Comprehensive bioactivity and chemical characterization of the endemic plant Scorzonera hieraciifolia Hayek extracts: A promising source of bioactive compounds
Dall'Acqua_2020_Molecules_25_Chromatographic Separation of Breynia retusa (Dennst.) Alston Bark, Fruit and Leaf Constituents from Bioactive Extracts
Dalva_2020_Cells_9_244Pathogenic Carboxyl Ester Lipase (CEL) Variants Interact with the Normal CEL Protein in Pancreatic Cells
Damodaran_2020_Neurochem.Int__104785The nootropic and anticholinesterase activities of Clitoria ternatea Linn. root extract: Potential treatment for cognitive decline
Damuka_2020_Pharmacol.Rep__Discovery of dual cation-pi inhibitors of acetylcholinesterase: design, synthesis and biological evaluation
Daneshvar_2020_Am.J.Physiol.Cell.Physiol__Premature satellite cell activation before injury accelerates myogenesis and disrupts neuromuscular junction maturation in regenerating muscle
Dar_2020_Cell.Mol.Neurobiol_40_313Elucidating Critical Proteinopathic Mechanisms and Potential Drug Targets in Neurodegeneration
Dar_2020_Sci.Rep_10_17322Biomarkers for the toxicity of sublethal concentrations of triclosan to the early life stages of carps
Darabi_2020_Bioinformation_16_702Studies on the cholinesterases inhibiting compounds from the Cassiopea andromeda venom
Dare_2020_Front.Behav.Neurosci_14_152The Reversal of Memory Deficits in an Alzheimer's Disease Model Using Physical and Cognitive Exercise
Darios_2020_Front.Neurosci_14_74Lipids in the Physiopathology of Hereditary Spastic Paraplegias
Das_2020_Molecules_25_Small Molecule Soluble Epoxide Hydrolase Inhibitors in Multitarget and Combination Therapies for Inflammation and Cancer
Dassanayake_2020_Clin.Toxicol.(Phila)__1Subacute and chronic neuropsychological sequalae of acute organophosphate pesticide self-poisoning: a prospective cohort study from Sri Lanka
Deacon_2020_Nat.Rev.Endocrinol_16_642Dipeptidyl peptidase 4 inhibitors in the treatment of type 2 diabetes mellitus
Deb_2020_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_240_108912Acetylcholinesterase and antioxidant responses in freshwater teleost, Channa punctata exposed to chlorpyrifos and urea
Deepa_2020_J.Ethnopharmacol__Dracocephalum moldavica attenuates scopolamine-induced cognitive impairment through activation of hippocampal ERK-CREB signaling in mice
Deganutti_2020_J.Chem.Inf.Model__A Supervised Molecular Dynamics Approach to Unbiased Ligand-Protein Unbinding
Delgado_2020_BMJ.Open_10_e029172Potentially inappropriate prescribing in dementia: a state-of-the-art review since 2007
Delu_2020_Retina_Publish Ahead of Print_Systemic Medication Use and the Incidence and Growth of Geographic Atrophy in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT)
Demine_2020_Diabetologia_63_825A nanobody-based nuclear imaging tracer targeting dipeptidyl peptidase 6 to determine the mass of human beta cell grafts in mice
Denesyuk_2020_PLoS.One_15_e0229376The acid-base-nucleophile catalytic triad in ABH-fold enzymes is coordinated by a set of structural elements
Deng_2020_Acta.Pharm.Sin.B_10_582Monoacylglycerol lipase inhibitors: modulators for lipid metabolism in cancer malignancy, neurological and metabolic disorders
Deng_2020_Eur.J.Med.Chem_198_112353Therapeutic potential of targeting alpha/beta-Hydrolase domain-containing 6 (ABHD6)
Deng_2020_Exp.Ther.Med_20_159miR-132 improves the cognitive function of rats with Alzheimer's disease by inhibiting the MAPK1 signal pathway
Derba-Maceluch_2020_Front.Plant.Sci_11_651Cell Wall Acetylation in Hybrid Aspen Affects Field Performance, Foliar Phenolic Composition and Resistance to Biological Stress Factors in a Construct-Dependent Fashion
Deshpande_2020_Ann.N.Y.Acad.Sci_1480_219Intramuscular atenolol and levetiracetam reduce mortality in a rat model of paraoxon-induced status epilepticus
Despotovic_2021_Biorxiv__Widespread Utilization of Diverse Organophosphate Pollutants by Marine Bacteria
Detering_2020_PLoS.One_15_e0244290Generation of 4-vinylguaiacol through a novel high-affinity ferulic acid decarboxylase to obtain smoke flavours without carcinogenic contaminants
Devanand_2020_J.Alzheimers.Dis__Odor Identification Impairment and Change with Cholinesterase Inhibitor Treatment in Mild Cognitive Impairment
Devidas_2020_Nat.Prod.Res__1Two undescribed diarylheptanoids from green husk of Carya illinoinensis as acetylcholinesterase inhibitors
Devita_2020_J.Clin.Exp.Neuropsychol__1Longitudinal investigation of the role of cognitive reserve in the evolution of dementia in outpatients prescribed AChEI
Deyhim_2020_Clinicoecon.Outcomes.Res_12_69Impact of Sugammadex Versus Neostigmine/Glycopyrrolate on Perioperative Efficiency
Di Paola_2020_Toxicon__Latrodectism in Italy: First report of successful treatment of L. tredecimguttatus envenomation using L. mactans antivenom from North America
Dietrich_2020_Mol.Microbiol__The C-terminal domain of Corynebacterium glutamicum mycoloyltransferase A is composed of five repeated motifs involved in cell wall binding and stability
Dietzen_2020_Plant.Physiol_184_2120The Transcription Factor EIL1 Participates in the Regulation of Sulfur-Deficiency Response
Dighe_2020_ACS.Omega_5_30971Structure-Based Scaffold Repurposing toward the Discovery of Novel Cholinesterase Inhibitors
Dimarogona_2020_FEBS.Lett__The crystal structure of a Fusarium oxysporum feruloyl esterase that belongs to the tannase family
Ding_2020_Chemosphere_255_127007Elucidating the potential neurotoxicity of chiral phenthoate: Molecular insight from experimental and computational studies
Ding_2020_Int.J.Biol.Macromol_148_333Characterization of EstZY: A new acetylesterase with 7-aminocephalosporanic acid deacetylase activity from Alicyclobacillus tengchongensis
Ding_2020_J.Hazard.Mater_396_122693Toxicological effects of nano- and micro-polystyrene plastics on red tilapia: Are larger plastic particles more harmless?
Ding_2020_Microb.Cell.Fact_19_114Development of a whole-cell biocatalyst for diisobutyl phthalate degradation by functional display of a carboxylesterase on the surface of Escherichia coli
Dione_2020_Cells_9_Mgll Knockout Mouse Resistance to Diet-Induced Dysmetabolism Is Associated with Altered Gut Microbiota
Disalvo_2020_Eur.J.Clin.Pharmacol__Multidisciplinary perspectives on medication-related decision-making for people with advanced dementia living in long-term care: a critical incident analysis
Djafri_2020_Heliyon_6_e05754Experimental spectral characterization, Hirshfeld surface analysis, DFT/TD-DFT calculations and docking studies of (2Z,5Z)-5-(4-nitrobenzylidene)-3-N(2-methoxyphenyl)-2-N'(2-methoxyphenylimino) thiazolidin-4-one
Dobiasova_2020_Antioxidants.(Basel)_9_Multidrug Resistance Modulation Activity of Silybin Derivatives and Their Anti-inflammatory Potential
Dockalova_2020_Comput.Struct.Biotechnol.J_18_922Fluorescent substrates for haloalkane dehalogenases: Novel probes for mechanistic studies and protein labeling
Dokla_2020_Eur.J.Med.Chem_186_111850Development of benzimidazole-based derivatives as antimicrobial agents and their synergistic effect with colistin against gram-negative bacteria
Dolui_2020_Plant.Physiol_184_693Functional Omics Identifies Serine Hydrolases That Mobilize Storage Lipids during Rice Seed Germination
Dolui_2020_Sci.Rep_10_15191Activity-based protein profiling of rice (Oryza sativa L.) bran serine hydrolases
Donadon_2020_Surgery_168_419Hepatic uptake index in the hepatobiliary phase of gadolinium ethoxybenzyl diethylenetriamine penta acetic acid-enhanced magnetic resonance imaging estimates functional liver reserve and predicts post-hepatectomy liver failure
Dong_2020_Food.Funct_11_9503In vitro gastrointestinal digestibility of phytosterol oleogels: influence of self-assembled microstructures on emulsification efficiency and lipase activity
Dong_2020_J.Agric.Food.Chem__Biofilm polysaccharide display platform: A natural, renewable, and biocompatible material for improved lipase performance
Dong_2020_J.Appl.Toxicol__Development of a practical prediction scoring system for severe acute organophosphate poisoning
Donkervoort_2020_Am.J.Med.Genet.A_182_2272Biallelic loss of function variants in SYT2 cause a treatable congenital onset presynaptic myasthenic syndrome
Dontukurthy_2020_Saudi.J.Anaesth_14_244Myasthenia gravis and sugammadex: A case report and review of the literature
Dornelles_2020_Neurochem.Res_45_2456Ellagic Acid Inhibits Neuroinflammation and Cognitive Impairment Induced by Lipopolysaccharides
Dos Santos Morais_2020_Sci.Total.Environ_715_136937Genotoxic, metabolic, and biological responses of Chironomus sancticaroli Strixino & Strixino, 1981 (Diptera: Chironomidae) after exposure to BBP
Dos Santos_2020_Biotechnol.Appl.Biochem__Application of lipase immobilized on a hydrophobic support for the synthesis of aromatic esters
Dos Santos_2020_Parasit.Vectors_13_293Insecticide resistance, fitness and susceptibility to Zika infection of an interbred Aedes aegypti population from Rio de Janeiro, Brazil
Dou_2020_Bioresour.Technol_317_123984A novel carboxylesterase from Acinetobacter sp. JNU9335 for efficient biosynthesis of Edoxaban precursor with high substrate to catalyst ratio
Douafer_2020_Environ.Sci.Pollut.Res.Int__Seasonal variation of biomarker responses in Cantareus aspersus and physic-chemical properties of soils from Northeast Algeria
Douglas_2020_J.Obstet.Gynaecol.Can_43_124Guideline No. 410: Prevention, Screening, Diagnosis, and Pregnancy Management for Fetal Neural Tube Defects
Dourson_2020_Regul.Toxicol.Pharmacol__104616A commentary on some epidemiology data for chlorpyrifos
Douville_2020_Br.J.Anaesth_125_986Genetic mutations associated with susceptibility to perioperative complications in a longitudinal biorepository with integrated genomic and electronic health records
Drabent_2020_Am.J.Surg.Pathol_44_1389PHOX2B Immunostaining: A Simple and Helpful Tool for the Recognition of Ganglionic Cells and Diagnosis of Hirschsprung Disease
Droguerre_2020_Front.Neurosci_14_563Efficacy of THN201, a Combination of Donepezil and Mefloquine, to Reverse Neurocognitive Deficits in Alzheimer's Disease
Drury_2020_Front.Oncol_10_1185Inhibition of Fatty Acid Synthase Upregulates Expression of CD36 to Sustain Proliferation of Colorectal Cancer Cells
Du-Carree_2020_Aquat.Toxicol_230_105687Impact of chronic exposure of rainbow trout, Oncorhynchus mykiss, to low doses of glyphosate or glyphosate-based herbicides
Du_2020_Biomolecules_10_Insecticidal and Enzyme Inhibitory Activities of Isothiocyanates against Red Imported Fire Ants, Solenopsis invicta
Du_2020_Bioorg.Med.Chem.Lett__127659Novel deoxyvasicinone and tetrahydro-beta-carboline hybrids as inhibitors of acetylcholinesterase and amyloid beta aggregation
Du_2020_EJNMMI.Res_10_67PET imaging of soluble epoxide hydrolase in non-human primate brain with [(18)F]FNDP
Du_2020_J.Hazard.Mater_408_124901Mechanistic insight into esterase-catalyzed hydrolysis of phthalate esters (PAEs) based on integrated multi-spectroscopic analyses and docking simulation
Du_2020_Prostaglandins.Leukot.Essent.Fatty.Acids_160_102160Role of oxylipins generated from dietary PUFAs in the modulation of endothelial cell function
Duan_2020_J.Biol.Chem_295_18625Ascertaining the biochemical function of an essential pectin methylesterase in the gut microbe Bacteroides thetaiotaomicron
Duarte-Restrepo_2020_PLoS.One_15_e0231310Effects of chlorpyrifos on the crustacean Litopenaeus vannamei
Duarte_2020_Sci.Total.Environ_712_136564Depressed, hypertense and sore: Long-term effects of fluoxetine, propranolol and diclofenac exposure in a top predator fish
Dudai_2020_PLoS.Biol_18_e3000613Barrel cortex VIP/ChAT interneurons suppress sensory responses in vivo
Dufort-Gervais_2020_Sci.Rep_10_6956Neuroligin-1 is altered in the hippocampus of Alzheimer's disease patients and mouse models, and modulates the toxicity of amyloid-beta oligomers
Dully_2020_J.Colloid.Interface.Sci_573_176Modulating the release of pharmaceuticals from lipid cubic phases using a lipase inhibitor
Dungdung_2020_J.Family.Med.Prim.Care_9_1873Correlation and prognostic significance of serum amylase, serum lipase, and plasma cholinesterase in acute organophosphorus poisoning
Durgun_2020_J.Enzyme.Inhib.Med.Chem_35_950Synthesis, characterisation, biological evaluation and in silico studies of sulphonamide Schiff bases
Dutt_2020_Physiol.Behav_222_112935Differential effects of alprazolam against methylphenidate-induced neurobehavioral alterations
Dutta_2020_Psychiatry.Res_293_113397Efficacy of donepezil for the attenuation of memory deficits associated with electroconvulsive therapy
Early_2020_Sr.Care.Pharm_35_207Changes in Psychotropic Prescribing for Patients With Dementia, 2014-2016: Potential implications for Pharmacists
Eastman_2020_ACS.Cent.Sci_6_672Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19
Ebokaiwe_2020_Naunyn.Schmiedebergs.Arch.Pharmacol__1Selenium nanoparticles and metformin ameliorate streptozotocin-instigated brain oxidative-inflammatory stress and neurobehavioral alterations in rats
Eckroat_2020_Int.J.Mol.Sci_21_Merged Tacrine-Based, Multitarget-Directed Acetylcholinesterase Inhibitors 2015-Present: Synthesis and Biological Activity
Edin_2020_Cells_9_Vascular Lipidomic Profiling of Potential Endogenous Fatty Acid PPAR Ligands Reveals the Coronary Artery as Major Producer of CYP450-Derived Epoxy Fatty Acids
Eguchi_2020_Biochem.Biophys.Res.Commun_523_214Overexpression of Dok-7 in skeletal muscle enhances neuromuscular transmission with structural alterations of neuromuscular junctions: Implications in robustness of neuromuscular transmission
Ehinger_2020_EMBO.Mol.Med__e10889Huntingtin phosphorylation governs BDNF homeostasis and improves the phenotype of Mecp2 knockout mice
Ehrich_2020_Toxicology__152586Effects of Polyhydroxyfullerenes on Organophosphate-Induced Toxicity in Mice
Eissa_2020_Biomolecules_10_Simultaneous Blockade of Histamine H(3) Receptors and Inhibition of Acetylcholine Esterase Alleviate Autistic-Like Behaviors in BTBR T+ tf/J Mouse Model of Autism
Eissa_2020_Int.J.Mol.Sci_21_The Dual-Active Histamine H3 Receptor Antagonist and Acetylcholine Esterase Inhibitor E100 Alleviates Autistic-Like Behaviors and Oxidative Stress in Valproic Acid Induced Autism in Mice
Ekici_2020_J.Equine.Vet.Sci_93_103218Affecting Lipid Metabolism Salivary MicroRNAs Expressions in Arabian Racehorses Before and After the Race
El Khayat El Sabbouri_2020_Food.Chem.Toxicol__111322Does the perigestational exposure to chlorpyrifos and/or high-fat diet affect respiratory parameters and diaphragmatic muscle contractility in young rats?
El Sayed_2020_Biomed.Pharmacother_127_110143New calogenin pregnane glycoside derivative from Huernia saudi- arabica and its Lipase and alpha-Glucosidase Inhibitory Activities
El-Azzouny_2020_Drug.Dev.Res__Structural and biological survey of 7-chloro-4-(piperazin-1-yl)quinoline and its derivatives
El-Hawary_2020_Saudi.J.Biol.Sci_27_2829HPLC-PDA-MS/MS profiling of secondary metabolites from Opuntia ficus-indica cladode, peel and fruit pulp extracts and their antioxidant, neuroprotective effect in rats with aluminum chloride induced neurotoxicity
El-Shiekh_2020_Biomed.Pharmacother_128_110303Hibiscus sabdariffa L.: A potent natural neuroprotective agent for the prevention of streptozotocin-induced Alzheimer's disease in mice
Elatico_2020_J.Mol.Graph.Model_100_107657Computational reverse engineering of the lipase from Pseudomonas aeruginosa PAO1: alpha-helices
Eleftheriou_2020_Molecules_25_In Silico Evaluation of the Effectivity of Approved Protease Inhibitors against the Main Protease of the Novel SARS-CoV-2 Virus
Elias_2020_Carbohydr.Polym_245_116549Structure and properties of lipase activated by cellulose-silica polyethersulfone membrane for production of pentyl valerate
Elibol_2020_Phytomedicine_79_153324Thymoquinone administration ameliorates Alzheimer's disease-like phenotype by promoting cell survival in the hippocampus of amyloid beta(1-42) infused rat model
Ellermann_2020_Cardiovasc.Toxicol_20_168Proarrhythmic Effect of Acetylcholine-Esterase Inhibitors Used in the Treatment of Alzheimer's Disease: Benefit of Rivastigmine in an Experimental Whole-Heart Model
Elmazoglu_2020_Neurochem.Int__104817Cannabinoid-profiled agents improve cell survival via reduction of oxidative stress and inflammation, and Nrf2 activation in a toxic model combining hyperglycemia+Abeta(1-42) peptide in rat hippocampal neurons
Emir_2020_J.Food.Biochem__e13165Characterization of phenolic profile by LC-ESI-MS/MS and enzyme inhibitory activities of two wild edible garlic: Allium nigrum L. and Allium subhirsutum L
Emir_2020_Turk.J.Pharm.Sci_17_36GC/MS Analysis of Alkaloids in Galanthus fosteri Baker and Determination of Its Anticholinesterase Activity
Emokpae_2020_Drug.Dev.Res__D-ribose-L-cysteine enhances memory task, attenuates oxidative stress and acetyl-cholinesterase activity in scopolamine amnesic mice
Emokpae_2020_Naunyn.Schmiedebergs.Arch.Pharmacol__D-Ribose-L-cysteine attenuates lipopolysaccharide-induced memory deficits through inhibition of oxidative stress, release of proinflammatory cytokines, and nuclear factor-kappa B expression in mice
Enayati_2020_Malar.J_19_258Evolution of insecticide resistance and its mechanisms in Anopheles stephensi in the WHO Eastern Mediterranean Region
Enderlin_2020_Epilepsia__Characterization of organophosphate-induced brain injuries in a convulsive mouse model of diisopropylfluorophosphate exposure
Eniyan_2020_World.J.Microbiol.Biotechnol_36_83Functional characterization of the endolysins derived from mycobacteriophage PDRPxv
Erdogan_2020_Eur.J.Med.Chem_212_113124Design, synthesis and biological evaluation of new benzoxazolone/benzothiazolone derivatives as multi-target agents against Alzheimer's disease
Erikci_2020_J.Biol.Chem_295_5891AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice
Ernst_2020_Nat.Commun_11_1026The structural basis of fungal glucuronoyl esterase activity on natural substrates
Erukainure_2020_Front.Pharmacol_11_592981Tetrahydrocannabinol-Rich Extracts From Cannabis Sativa L. Improve Glucose Consumption and Modulate Metabolic Complications Linked to Neurodegenerative Diseases in Isolated Rat Brains
Erukainure_2020_J.Ethnopharmacol__112744Dacryodes edulis (G. Don) H.J. Lam modulates glucose metabolism, cholinergic activities and Nrf2 expression, while suppressing oxidative stress and dyslipidemia in diabetic rats
Erukainure_2020_J.Food.Biochem__e13315Strawberry fruit (Fragaria x ananassa cv. Romina) extenuates iron-induced cardiac oxidative injury via effects on redox balance, angiotensin-converting enzyme, purinergic activities, and metabolic pathways
Erukainure_2020_J.Food.Biochem__e13576Bioactive compounds of African star apple (Chrysophyllum albidum G. Don) and its modulatory effect on metabolic activities linked to type 2 diabetes in isolated rat psoas muscle
Erukainure_2020_Metab.Brain.Dis_35_1417Casein micelles from bovine Milk exerts Neuroprotection by stalling metabolic complications linked to oxidative brain injury
Escoubet_2020_PLoS.One_15_e0234780ABHD11, a new diacylglycerol lipase involved in weight gain regulation
Esimbekova_2020_Dokl.Biol.Sci_491_43Gelatin and Starch: What Better Stabilizes the Enzyme Activity?
Esmaeilnejad_2020_Comp.Immunol.Microbiol.Infect.Dis_71_101503Status of oxidative stress, trace elements, sialic acid and cholinesterase activity in cattle naturally infected with Babesia bigemina
Esmangart_2020_Curr.Biol_30_4245Interplay between Anakonda, Gliotactin, and M6 for Tricellular Junction Assembly and Anchoring of Septate Junctions in Drosophila Epithelium
Espinosa_2020_Molecules_26_A Novel Chemical Profile of a Selective In Vitro Cholinergic Essential Oil from Clinopodium taxifolium (Kunth) Govaerts (Lamiaceae), a Native Andean Species of Ecuador
Esterly_2020_PLoS.One_15_e0228835Culex erythrothorax (Diptera: Culicidae): Activity periods, insecticide susceptibility and control in California (USA)
Estrela_2020_Chemosphere_271_129476Toxicity of polystyrene nanoplastics and zinc oxide to mice
Etienne_2020_J.Pharm.Biomed.Anal__113799Chemical characterization, antioxidant and enzyme inhibitory effects of Mitracarpus hirtus extracts
Evans_2020_J.Chem.Theory.Comput__Combining Machine Learning and Enhanced Sampling Techniques for Efficient and Accurate Calculation of Absolute Binding Free Energies
Everitt_2020_Aquat.Toxicol_228_105630Effects of weathered sediment-bound dilbit on freshwater amphipods (Hyalella azteca)
Ewere_2020_Sci.Total.Environ_742_140538The neonicotinoid insecticide imidacloprid, but not salinity, impacts the immune system of Sydney rock oyster, Saccostrea glomerata
Eze_2020_Heliyon_6_e04796Schistosomiasis prevention option: toxicological evaluation of Vernonia amygdalina on the tissues of Bulinus truncatus at different pH conditions
Fahmy_2020_J.Trace.Elem.Med.Biol_61_126505Biodistribution and toxicity assessment of copper nanoparticles in the rat brain
Faizan_2020_Open.Life.Sci_15_217Role of Strigolactones: Signalling and Crosstalk with Other Phytohormones
Falach_2020_Sci.Rep_10_9007The low density receptor-related protein 1 plays a significant role in ricin-mediated intoxication of lung cells
Falarz_2020_Plant.J_103_2025Characterization of the diversification of phospholipid:diacylglycerol acyltransferases in the green lineage
Fancellu_2020_J.Enzyme.Inhib.Med.Chem_35_211Novel tacrine-benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer's Disease
Faraone_2020_Foods_9_Phytochemicals of Minthostachys diffusa Epling and Their Health-Promoting Bioactivities
Farkhondeh_2020_Environ.Sci.Pollut.Res.Int__Oxidative stress and mitochondrial dysfunction in organophosphate pesticide-induced neurotoxicity and its amelioration: a review
Farombi_2020_Metab.Brain.Dis__Kolaviron ameliorates behavioural deficit and injury to striatal dopaminergic terminals via modulation of oxidative burden, DJ-1 depletion and CD45R(+) cells infiltration in MPTP-model of Parkinson's disease
Farombi_2020_Psychopharmacology.(Berl)_237_1027Kolaviron via anti-inflammatory and redox regulatory mechanisms abates multi-walled carbon nanotubes-induced neurobehavioral deficits in rats
Farombi_2020_Psychopharmacology.(Berl)_237_3225Kolaviron protects against nigrostriatal degeneration and gut oxidative damage in a stereotaxic rotenone model of Parkinson's disease
Farrugia_2020_Front.Neurol_11_604A Practical Approach to Managing Patients With Myasthenia Gravis-Opinions and a Review of the Literature
Farsalinos_2020_Eur.Respir.J_56_COVID-19 and the nicotinic cholinergic system
Farsalinos_2020_Int.J.Mol.Sci_21_Nicotinic Cholinergic System and COVID-19: In Silico Identification of an Interaction between SARS-CoV-2 and Nicotinic Receptors with Potential Therapeutic Targeting Implications
Farsalinos_2020_Toxicol.Rep_7_658Editorial: Nicotine and SARS-CoV-2: COVID-19 may be a disease of the nicotinic cholinergic system
Faucher_2020_Cell.Chem.Biol_27_937Strategies for Tuning the Selectivity of Chemical Probes that Target Serine Hydrolases
Feja_2020_Neuropharmacol_162_107814The novel MAGL inhibitor MJN110 enhances responding to reward-predictive incentive cues by activation of CB1 receptors
Felemban_2020_Chem.Res.Toxicol_33_2310Phenyl Saligenin Phosphate Disrupts Cell Morphology and the Actin Cytoskeleton in Differentiating H9c2 Cardiomyoblasts and Human-Induced Pluripotent Stem-Cell-Derived Cardiomyocyte Progenitor Cells
Fellner_2020_ACS.Infect.Dis_6_2771Structural basis for the inhibitor and substrate specificity of the unique Fph serine hydrolases of Staphylococcus aureus
Felsztyna_2020_Biochim.Biophys.Acta.Biomembr__183188Sensing molecular organizational changes through the catalytic activity of acetylcholinesterase from erythrocyte membranes in Langmuir-Blodgett films
Feng_2020_Anal.Chim.Acta_1097_176A magnetic SERS immunosensor for highly sensitive and selective detection of human carboxylesterase 1 in human serum samples
Feng_2020_Angew.Chem.Int.Ed.Engl_59_7209A Hydrolase-Catalyzed Cyclization Forms the Fused Bicyclic beta-Lactone in Vibralactone
Feng_2020_Environ.Sci.Process.Impacts_22_2332Biodegradation mechanism of polycaprolactone by a novel esterase MGS0156: a QM/MM approach
Feng_2020_Front.Physiol_11_595009Functional Analyses of House Fly Carboxylesterases Involved in Insecticide Resistance
Fentabil_2020_Chem.Biol.Interact__108980In vivo efficacy of the Reactive Skin Decontamination Lotion (RSDL(R)) kit against organophosphate and carbamate pesticides
Fernandes_2020_J.Adhes.Dent_22_265Esterase Inhibition and Copper Release from Copper Iodide Dental Adhesives - An In Vitro Study
Fernandez-Aulis_2020_Food.Chem_309_125796New acylated cyanidin glycosides extracted from underutilized potential sources: Enzymatic synthesis, antioxidant activity and thermostability
Fernandez-Lorente_2020_Methods.Mol.Biol_2100_143Immobilization of Lipases by Adsorption on Hydrophobic Supports: Modulation of Enzyme Properties in Biotransformations in Anhydrous Media
Fernandez-Poyatos_2020_J.Anal.Methods.Chem_2020_8885169Study on Three Sarcocapnos Species as Potential Sources of Bioactive Compounds: Relation between Phenolic Content and Bioactivity by Multivariate Analysis
Fernando_2020_Parasit.Vectors_13_407Resistance to commonly used insecticides and underlying mechanisms of resistance in Aedes aegypti (L.) from Sri Lanka
Ferrara_2020_Waste.Manag_119_215New insight into microbial degradation of mycotoxins during anaerobic digestion
Ferre_2020_Sci.Total.Environ_726_138058Biomonitoring of the hematological, biochemical and genotoxic effects of the mixture cypermethrin plus chlorpyrifos applications in bovines
Ferreira-Junior_2020_Eur.J.Neurosci_51_991Dorsal hippocampus cholinergic and nitrergic neurotransmission modulates the cardiac baroreflex function in rats
Ferreira_2020_Evid.Based.Complement.Alternat.Med_2020_3825629In Vitro Screening for Acetylcholinesterase Inhibition and Antioxidant Activity of Quercus suber Cork and Corkback Extracts
Ferreira_2020_Neurotox.Res_38_50Intrastriatal Quinolinic Acid Administration Impairs Redox Homeostasis and Induces Inflammatory Changes: Prevention by Kynurenic Acid
Ferri_2020_Clin.Transl.Gastroenterol_11_e00116Reduced Lysosomal Acid Lipase Activity in Blood and Platelets Is Associated With Nonalcoholic Fatty Liver Disease
Fertan_2020_Genes.Brain.Behav__e12696The Effect of Background Strain on the Behavioural Phenotypes of the MDGA2(+/-) Mouse Model of Autism Spectrum Disorder
Fiala_2020_J.Alzheimers.Dis__Omega-3 Fatty Acids Increase Amyloid-beta Immunity, Energy, and Circadian Rhythm for Cognitive Protection of Alzheimer's Disease Patients Beyond Cholinesterase Inhibitors
Fiebig_2020_Nat.Commun_11_4723Structural and mechanistic basis of capsule O-acetylation in Neisseria meningitidis serogroup A
Figueiredo_2020_Environ.Res__110051Warming enhances lanthanum accumulation and toxicity promoting cellular damage in glass eels (Anguilla anguilla)
Figueroa-Villar_2020_Curr.Med.Chem__Review about structure and evaluation of reactivators of Acetylcholinesterase inhibited with neurotoxic organophosphorus compounds
Figura_2020_Neurol.Neurochir.Pol__In search of Parkinson's disease biomarkers - is the answer in our mouths? A systematic review of the literature on salivary biomarkers of Parkinson's disease
Filipe_2020_J.Chem.Theory.Comput_16_4734Effect of Protein Flexibility from Coarse-Grained Elastic Network Parameterizations on the Calculation of Free Energy Profiles of Ligand Binding
Filova_2020_Neurosci.Lett__134912Expression of synaptic proteins in the hippocampus is modulated by neonatal oxytocin treatment
Finger_2020_EMBO.J__e103889Proteasomal degradation induced by DPP9-mediated processing competes with mitochondrial protein import
Fink_2020_Ann.Intern.Med__Benefits and Harms of Prescription Drugs and Supplements for Treatment of Clinical Alzheimer-Type Dementia: A Systematic Review and Meta-analysis
Fiore_2020_Harmful.Algae_92_101737Guanitoxin, re-naming a cyanobacterial organophosphate toxin
Firdaus_2020_Drug.Chem.Toxicol__1Centella asiatica prevents D-galactose-Induced cognitive deficits, oxidative stress and neurodegeneration in the adult rat brain
Fishbein_2020_Pharmacol.Ther__107670Carcinogenesis: Failure of resolution of inflammation?
Fitzgerald_2020_Front.Behav.Neurosci_14_620119Repurposing Cholinesterase Inhibitors as Antidepressants? Dose and Stress-Sensitivity May Be Critical to Opening Possibilities
Fitzgerald_2020_Transl.Psychiatry_10_255The cholinesterase inhibitor donepezil has antidepressant-like properties in the mouse forced swim test
Fjeld_2020_Pancreatology__Characterization of CEL-DUP2: Complete duplication of the carboxyl ester lipase gene is unlikely to influence risk of chronic pancreatitis
Flaugnatti_2020_EMBO.J_39_e104129Structural basis for loading and inhibition of a bacterial T6SS phospholipase effector by the VgrG spike
Flokova_2020_Plant.Methods_16_125An improved strategy to analyse strigolactones in complex sample matrices using UHPLC-MS/MS
Flores_2020_J.Food.Biochem__e13442Eugenia uniflora fruit extract exerts neuroprotective effect on chronic unpredictable stress-induced behavioral and neurochemical changes
Flygaard_2020_Nat.Commun_11_5342Type III ATP synthase is a symmetry-deviated dimer that induces membrane curvature through tetramerization
Flynn_2020_J.Appl.Toxicol__The effects of combinations of limited ration and diazinon exposure on acetylcholinesterase activity, growth and reproduction in Oryzias latipes, the Japanese medaka
Foguth_2020_Neurotoxicol.Teratol__106907Single and mixture per- and polyfluoroalkyl substances accumulate in developing Northern leopard frog brains and produce complex neurotransmission alterations
Folle_2020_Chemosphere__1287852,4,6-Tribromophenol is toxic to Oreochromis niloticus (Linnaeus, 1758) after trophic and subchronic exposure
Fowler_2020_Handb.Exp.Pharmacol_258_373Molecular Mechanisms Associated with Nicotine Pharmacology and Dependence
Fraga_2020_3.Biotech_10_454Catalytic and physical features of a naturally immobilized Yarrowia lipolytica lipase in cell debris (LipImDebri) displaying high thermostability
Fragoso-Saavedra_2020_BMC.Infect.Dis_20_765A parallel-group, multicenter randomized, double-blinded, placebo-controlled, phase 2/3, clinical trial to test the efficacy of pyridostigmine bromide at low doses to reduce mortality or invasive mechanical ventilation in adults with severe SARS-CoV-2 infection: the Pyridostigmine In Severe COvid-19 (PISCO) trial protocol
Francois_2020_Pharmacoepidemiol.Drug.Saf__Determinants of antidementia drug prescription in patients older than 65: A latent class analysis
Freitas_2020_Environ.Res_188_109846Biochemical performance of mussels, cockles and razor shells contaminated by paralytic shellfish toxins
Frileux_2020_Front.Psychiatry_11_554Late-Onset OCD as a Potential Harbinger of Dementia With Lewy Bodies: A Report of Two Cases
Fronza_2020_ACS.Chem.Neurosci_11_1259QTC-4-MeOBnE rescues scopolamine-induced memory deficits in mice by targeting oxidative stress, neuronal plasticity and apoptosis
Fu_2020_Bioorg.Chem_99_103888One-pot cascade synthesis of benzopyrans and dihydropyrano[c]chromenes catalyzed by lipase TLIM
Fu_2020_J.Enzyme.Inhib.Med.Chem_35_118Design, synthesis and evaluation of quinolinone derivatives containing dithiocarbamate moiety as multifunctional AChE inhibitors for the treatment of Alzheimer's disease
Fu_2020_Mol.Plant.Pathol_21_1337The basal transcription factor II H subunit Tfb5 is required for stress response and pathogenicity in the tangerine pathotype of Alternaria alternata
Fu_2020_Rapid.Commun.Mass.Spectrom__e8721Identification of S419 on human serum albumin as a novel biomarker for sarin and cyclosarin exposure
Funmilola_2020_J.Oleo.Sci_69_941Involvement of Cholinergic and Redox Impairments in Insecticidal Properties of Essential Oils from Fertility Tree and Horseradish Tree Leaves in Fruit Fly (Drosophila melanogaster)
Furqan_2020_Biomolecules_10_Cannabis Constituents and Acetylcholinesterase Interaction: Molecular Docking, In Vitro Studies and Association with CNR1 rs806368 and ACHE rs17228602
Furuhashi_2020_Cardiovasc.Diabetol_19_89Treatment with anagliptin, a DPP-4 inhibitor, decreases FABP4 concentration in patients with type 2 diabetes mellitus at a high risk for cardiovascular disease who are receiving statin therapy
Fuster_2020_Toxicol.Appl.Pharmacol_404_115178Effects of silver nanoparticles on T98G human glioblastoma cells
Gaaied_2020_Environ.Sci.Pollut.Res.Int_27_36862,4-Dichlorophenoxyacetic acid herbicide effects on zebrafish larvae: development, neurotransmission and behavior as sensitive endpoints
Gabr_2020_Bioorg.Med.Chem.Lett_30_127370Discovery of biphenyl pyrazole scaffold for neurodegenerative diseases: A novel class of acetylcholinesterase-centered multitargeted ligands
Gabr_2020_J.Med.Chem_63_9695MicroRNA-Based Multitarget Approach for Alzheimer's Disease: Discovery of the First-In-Class Dual Inhibitor of Acetylcholinesterase and MicroRNA-15b Biogenesis
Gagnaire_2020_Environ.Sci.Pollut.Res.Int_27_3612Effects of in vivo exposure to tritium: a multi-biomarker approach using the fathead minnow, Pimephales promelas
Gaire_2020_Pestic.Biochem.Physiol_169_104667Bed bugs, Cimex lectularius L., exhibiting metabolic and target site deltamethrin resistance are susceptible to plant essential oils
Galarce-Bustos_2020_Food.Funct__Usage of supercritical fluid techniques to obtain bioactive alkaloid-rich extracts from cherimoya peel and leaves: extract profiles and their correlation with antioxidant properties and acetylcholinesterase and alpha-glucosidase inhibitory activities
Gallegos_2020_Neurotoxicol__INTRANASAL GLYPHOSATE-BASED HERBICIDE ADMINISTRATION ALTERS THE REDOX BALANCE AND THE CHOLINERGIC SYSTEM IN THE MOUSE BRAIN
Gallo_2020_Curr.Atheroscler.Rep_22_63Familial Chylomicronemia Syndrome (FCS): Recent Data on Diagnosis and Treatment
Galmes_2020_ACS.Catal_10_1938Exploring the Origin of Amidase Substrate Promiscuity in CALB by a Computational Approach
Gambino_2020_ACS.Med.Chem.Lett_11_1893Methyl Scanning and Revised Binding Mode of 2-Pralidoxime, an Antidote for Nerve Agent Poisoning
Gan_2020_Antiviral.Res__104996Antiviral activity against Middle East Respiratory Syndrome Coronavirus by Montelukast, an anti-asthma drug
Gan_2020_Food.Sci.Nutr_8_5128Lactobacillus plantarum KSFY06 and geniposide counteract montmorillonite-induced constipation in Kunming mice
Gan_2020_J.Neurosci_40_8088SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins
Ganesh_2020_Neurol.Clin.Pract_10_362Practice Current: How do you manage mild cognitive impairment?
Ganjali_2020_Semin.Arthritis.Rheum_50_769High-density lipoprotein functionality in systemic lupus erythematosus
Gao_2020_Environ.Int_143_105940Enantioselective disposition and metabolic products of isofenphos-methyl in rats and the hepatotoxic effects
Gao_2020_Environ.Sci.Pollut.Res.Int_27_45712Ecological risk assessment of heavy metals in fish from the Dianchi Lake, China using the integrated biomarker response approach
Gao_2020_Food.Chem_330_127225Identification of an alkaline lipase capable of better enrichment of EPA than DHA due to fatty acids selectivity and regioselectivity
Gao_2020_Front.Genet_11_589Insecticidal Activity of Artemisia vulgaris Essential Oil and Transcriptome Analysis of Tribolium castaneum in Response to Oil Exposure
Gao_2020_Front.Physiol_11_1111Expression Profiling of Plant Cell Wall-Degrading Enzyme Genes in Eucryptorrhynchus scrobiculatus Midgut
Gao_2020_J.Agric.Food.Chem_68_12141Effects of Different Dietary Flavonoids on Dipeptidyl Peptidase-IV Activity and Expression: Insights into Structure-Activity Relationship
Gao_2020_Pest.Manag.Sci_76_3596Geographic variation in sexual communication in the cotton bollworm, Helicoverpa armigera
Garate_2020_Aquat.Toxicol_225_105544A comparative study of enzymatic and immunological parameters in Planorbarius corneus and Biomphalaria glabrata exposed to the organophosphate chlorpyrifos
Garcia-Garcia_2020_Eur.J.Hosp.Pharm__Discontinuation of cholinesterase inhibitor treatment in institutionalised patients with advanced dementia
Gardela_2020_Genes.(Basel)_11_Semen Modulates the Expression of NGF, ABHD2, VCAN, and CTEN in the Reproductive Tract of Female Rabbits
Garibaldi_2020_Autoimmun.Rev__102498Muscle involvement in myasthenia gravis: Expanding the clinical spectrum of myasthenia-myositis association from a large cohort of patients
Garrido-Suarez_2020_Brain.Res.Bull_165_185Anti-hypernociceptive and anti-inflammatory effects of JM-20: A novel hybrid neuroprotective compound
Garzon_2020_Food.Funct_11_4994Isolation and identification of cholesterol esterase and pancreatic lipase inhibitory peptides from brewer's spent grain by consecutive chromatography and mass spectrometry
Gasca_2020_Food.Chem.Toxicol__111703Acetylcholinesterase inhibitory activity, anti-inflammatory, and neuroprotective potential of Hippeastrum psittacinum (Ker Gawl.) Herb (Amaryllidaceae)
Gashout_2020_J.Insect.Physiol__104014Impact of sublethal exposure to synthetic and natural acaricides on honey bee (Apis mellifera) memory and expression of genes related to memory
Gatta_2020_Biomedicines_8_Possible Correlation between Cholinergic System Alterations and Neuro/Inflammation in Multiple Sclerosis
Gaur_2020_J.Agric.Food.Chem__Novel Cinnamoylated Flavoalkaloids Identified in Tea with Acetylcholinesterase Inhibition Effect
Gavrilovic_2020_Sci.Total.Environ_750_141569Hepatic oxidative stress and neurotoxicity in Pelophylax kl. esculentus frogs: Influence of long-term exposure to a cyanobacterial bloom
Gawande_2020_J.Chromatogr.A_1637_461836Effect-directed profiling of Ficus religiosa leaf extracts for multipotent compounds via 12 effect-directed assays
Gazwi_2020_Ecotoxicol.Environ.Saf_192_110297Mitigation of lead neurotoxicity by the ethanolic extract of Laurus leaf in rats
Ge_2020_Int.Immunopharmacol_85_106604Decreased T-cell mediated hepatic injury in concanavalin A-treated PLRP2-deficient mice
Gebremedhin_2020_Toxicol.Lett_332_36In vitro decontamination efficacy of the RSDL (Reactive Skin Decontamination Lotion Kit) lotion component against riot control agents: Capsaicin, Mace (CN) and CS
Genc Bilgicli_2020_Bioorg.Chem_101_103969Novel propanolamine derivatives attached to 2-metoxifenol moiety: Synthesis, characterization, biological properties, and molecular docking studies
Georgiev_2020_Molecules_25_Recent Progress in Amaryllidaceae Biotechnology
Georgios_2020_Med.Chem__Multi-target Directed Compounds with Antioxidant and/or Antiinflammatory Properties as Potent Agents for Alzheimer's Disease
Gersel_2020_Eur.J.Neurol_27_644Cholinergic denervation in patients with idiopathic rapid eye movement sleep behaviour disorder
Gezegen_2020_Arch.Pharm.(Weinheim)__e2000334Synthesis, molecular docking, and biological activities of new cyanopyridine derivatives containing phenylurea
Ghafary_2020_Daru__Design, synthesis, and evaluation of novel cinnamic acid-tryptamine hybrid for inhibition of acetylcholinesterase and butyrylcholinesterase
Ghai_2020_CNS.Neurol.Disord.Drug.Targets_19_676Current Strategies and Novel Drug Approaches for Alzheimer Disease
Ghamari_2020_Chem.Biol.Drug.Des_95_279In silico and in vitro studies of two non-imidazole multiple targeting agents at histamine H3 receptors and cholinesterase enzymes
Gheshlaghi_2020_Crit.Rev.Toxicol__1Efficacy of fresh frozen plasma transfusion in comparison with conventional regimen in organophosphate poisoning treatment: a meta-analysis study
Ghobadian_2020_Mol.Divers_24_211Design, synthesis, in vivo and in vitro studies of 1,2,3,4-tetrahydro-9H-carbazole derivatives, highly selective and potent butyrylcholinesterase inhibitors
Gholami_2020_Arch.Biochem.Biophys__108574The long-term effects of delta(9)-tetrahydrocannabinol on microtubule dynamicity in rats
Gholami_2020_Arch.Physiol.Biochem__1Bromhexine and its inhibitory effect on lipase - kinetics and structural study
Ghosh_2020_Biomacromolecules_21_2896Biodegradable Polymer Theranostic Fluorescent Nanoprobe for Direct Visualization and Quantitative Determination of Antimicrobial Activity
Ghosh_2020_J.Biomol.Struct.Dyn__1Revealing the cholinergic inhibition mechanism of Alzheimer's by galantamine: a metadynamics simulation study
Ghosh_2020_Sci.Transl.Med_12_An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer's disease
Ghotbi_2020_Bioorg.Chem_103_104186Design, synthesis, biological evaluation, and docking study of novel dual-acting thiazole-pyridiniums inhibiting acetylcholinesterase and beta-amyloid aggregation for Alzheimer's disease
Ghribi_2020_Environ.Sci.Pollut.Res.Int__Trace elements and oxidative stress in the Ark shell Arca noae from a Mediterranean coastal lagoon (Bizerte lagoon, Tunisia): are there health risks associated with their consumption?
Giacomini_2020_J.Psychopharmacol_34_1449An acetylcholinesterase inhibitor, donepezil, increases anxiety and cortisol levels in adult zebrafish
Giebel_2020_Int.Psychogeriatr__1Ethnic disparities in the uptake of anti-dementia medication in young and late-onset dementia
Gihaz_2020_ChemCatChem_12_181Bridges to Stability: Engineering Disulfide Bonds Towards Enhanced Lipase Biodiesel Synthesis
Giunta_2020_ACS.Nano__Tuning the Properties of Natural Promiscuous Enzymes by Engineering Their Nano-environment
Giusto_2020_J.Comp.Neurol_528_231Compensatory changes in degenerating spinal motoneurons sustain functional sparing in the SOD1-G93A mouse model of amyotrophic lateral sclerosis
Glaros_2020_Arch.Toxicol_94_3249Discovery of treatment for nerve agents targeting a new metabolic pathway
Glasner_2020_FEBS.J_287_1323How enzyme promiscuity and horizontal gene transfer contribute to metabolic innovation
Glass_2020_Curr.Psychiatry.Rep_22_21Considerations and Current Trends in the Management of the Geriatric Patient on a Consultation-Liaison Service
Glavan_2020_Pestic.Biochem.Physiol_166_104567Comparison of sublethal effects of natural acaricides carvacrol and thymol on honeybees
Gnatyshyna_2020_Arch.Environ.Contam.Toxicol__Preliminary Study of Multiple Stress Response Reactions in the Pond Snail Lymnaea stagnalis Exposed to Trace Metals and a Thiocarbamate Fungicide at Environmentally Relevant Concentrations
Gnatyshyna_2020_Environ.Sci.Pollut.Res.Int__Multi-marker study of the responses of the Unio tumidus from the areas of small and micro hydropower plants at the Dniester River Basin, Ukraine
Goldberg_2020_Front.Endocrinol.(Lausanne)_11_593931A Comprehensive Update on the Chylomicronemia Syndrome
Goldman_2020_Alzheimers.Res.Ther_12_137Challenges and opportunities for improving the landscape for Lewy body dementia clinical trials
Golicnik_2020_J.Enzyme.Inhib.Med.Chem_35_261Evaluation of the paraoxonase-1 kinetic parameters of the lactonase activity by nonlinear fit of progress curves
Gomes_2020_Chemosphere_263_127985Sublethal effects of triclosan and triclocarban at environmental concentrations in silver catfish (Rhamdia quelen) embryos
Gomes_2020_Environ.Sci.Pollut.Res.Int_27_45742First characterization of the ecotoxicity of paraffin particles: assessment of biochemical effects in the marine polychaete Hediste diversicolor
Gomes_2020_Oxid.Med.Cell.Longev_2020_3960170Croton campestris A. St.-Hill Methanolic Fraction in a Chlorpyrifos-Induced Toxicity Model in Drosophila melanogaster: Protective Role of Gallic Acid
Gomez-Villegas_2020_Biology.(Basel)_9_Antioxidant, Antimicrobial, and Bioactive Potential of Two New Haloarchaeal Strains Isolated from Odiel Salterns (Southwest Spain)
Gong_2020_Front.Physiol_11_623612Susceptibility of Four Species of Aphids in Wheat to Seven Insecticides and Its Relationship to Detoxifying Enzymes
Gong_2020_J.Biomed.Nanotechnol_16_827Effect of Harmine and Its Derivatives Against Echinococcus granulosus and Comparison of DNA Damage Targets
Gonzales_2020_Sci.Rep_10_11235Plasma proteomics reveals markers of metabolic stress in HIV infected children with severe acute malnutrition
Gonzalez-Chavarria_2020_Biomolecules_10_Maytenus disticha Extract and an Isolated beta-Dihydroagarofuran Induce Mitochondrial Depolarization and Apoptosis in Human Cancer Cells by Increasing Mitochondrial Reactive Oxygen Species
Gonzalez_2020_Arch.Toxicol__The chemical convulsant diisopropylfluorophosphate (DFP) causes persistent neuropathology in adult male rats independent of seizure activity
Gonzalez_2020_Bioorg.Chem_98_103722Isoquinoline alkaloids from the roots of Zanthoxylum rigidum as multi-target inhibitors of cholinesterase, monoamine oxidase A and Abeta1-42 aggregation
Gorecki_2020_ACS.Med.Chem.Lett_11_65Cysteine-Targeted Insecticides against A. gambiae Acetylcholinesterase Are Neither Selective nor Reversible Inhibitors
Gorecki_2020_J.Biol.Chem_295_4079Rational design, synthesis and evaluation of uncharged, smart bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase
Goswami_2020_Appl.Biochem.Biotechnol_191_744Lipase Catalysis in Presence of Nonionic Surfactants
Goswami_2020_Brain.Res.Bull_165_108Involvement of endoplasmic reticulum stress in amyloid beta ((1-42))-induced Alzheimer's like neuropathological process in rat brain
Gould_2020_Neuropsychopharmacology_45_2219Modulation of arousal and sleep/wake architecture by M(1) PAM VU0453595 across young and aged rodents and nonhuman primates
Gowayed_2020_Eur.J.Pharmacol__173315Galantamine in rheumatoid arthritis: A cross talk of parasympathetic and sympathetic system regulates synovium-derived microRNAs and related pathogenic pathways
Grajales-Hernandez_2020_Appl.Microbiol.Biotechnol_104_10033Chitosan-based CLEAs from Aspergillus niger type A feruloyl esterase: high-productivity biocatalyst for alkyl ferulate synthesis
Granchi_2020_Eur.J.Med.Chem_209_112857Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors
Granger_2020_Elife_9_Cortical ChAT(+) neurons co-transmit acetylcholine and GABA in a target- and brain-region-specific manner
Greco_2020_Cephalalgia__333102420949201Peripheral changes of endocannabinoid system components in episodic and chronic migraine patients: A pilot study
Green_2020_Drugs.Real.World.Outcomes__Patterns of Potentially Inappropriate Bladder Antimuscarinic Use in People with Dementia: A Retrospective Cohort Study
Grinan-Ferre_2020_Neurotherapeutics__Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer's Disease
Grobe-Einsler_2020_Neurodegener.Dis__1Effects of Rivastigmine on Patients with Spinocerebellar Ataxia Type 3: A Case Series of Five Patients
Grossman_2020_J.Nat.Prod__Structural Revision of Garcinielliptin Oxide and Garcinielliptone E
Gu_2020_Front.Pediatr_8_338The rs1051931 G>A Polymorphism in the PLA2G7 Gene Confers Resistance to Immunoglobulin Therapy in Kawasaki Disease in a Southern Chinese Population
Gu_2020_J.Dairy.Sci__Sequencing of lipoprotein lipase gene in the Mediterranean river buffalo identified novel variants affecting gene expression
Gu_2020_J.Environ.Sci.Health.B__1Chlorpyrifos-induced toxicity has no gender selectivity in the early fetal brain
Guan_2020_Front.Bioeng.Biotechnol_8_1034Directed Evolution of Pseudomonas fluorescens Lipase Variants With Improved Thermostability Using Error-Prone PCR
Guan_2020_J.Cell.Physiol_235_10024miR-448-3p alleviates diabetic vascular dysfunction by inhibiting endothelial-mesenchymal transition through DPP-4 dysregulation
Guan_2020_Obes.Surg__Effect of Bariatric Surgery on Serum Enzyme Status in Obese Patients
Guedegba_2020_Chemosphere__128530Chronic effects of a binary insecticide Acer 35 EC on Nile tilapia Oreochromis niloticus through a multi-biomarker approach
Gueye_2020_Genes.(Basel)_11_Insecticide Resistance Profiling of Anopheles coluzzii and Anopheles gambiae Populations in the Southern Senegal: Role of Target Sites and Metabolic Resistance Mechanisms
Gui_2020_Exp.Cell.Res__112360Soluble epoxide hydrolase inhibitors improve angiogenic function of endothelial progenitor cells via ERK/p38-mediated miR-126 upregulation in myocardial infarction mice after exercise
Guieu_2020_Molecules_26_First Synthesis of Racemic Trans Propargylamino-Donepezil, a Pleiotrope Agent Able to Both Inhibit AChE and MAO-B, with Potential Interest against Alzheimer's Disease
Guimaraes_2020_J.Hazard.Mater_407_124833Toxic effects of naturally-aged microplastics on zebrafish juveniles: A more realistic approach to plastic pollution in freshwater ecosystems
Guimares_2020_Sci.Total.Environ_752_141936Toxicity of polystyrene nanoplastics in dragonfly larvae: An insight on how these pollutants can affect bentonic macroinvertebrates
Gulcan_2020_Comb.Chem.High.Throughput.Screen__A Recent Look into Natural Products that Have Potential to Inhibit Cholinesterases and Monoamine Oxidase B: Update on 2010-2019
Gulcan_2020_Curr.Pharm.Des__The main targets involved in neuroprotection for the treatment of Alzheimer's Disease and Parkinson Disease
Gulcin_2020_Bioorg.Chem_103_104171Synthesis of nitrogen, phosphorus, selenium and sulfur-containing heterocyclic compounds - Determination of their carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and alpha-glycosidase inhibition properties
Gunesch_2020_Redox.Biol_29_1013787-O-Esters of taxifolin with pronounced and overadditive effects in neuroprotection, anti-neuroinflammation, and amelioration of short-term memory impairment in vivo
Gunn_2020_Proc.Natl.Acad.Sci.U.S.A__The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage
Guo_2020_Anal.Chem_92_14806In Situ Generation of Prussian Blue by MIL-53 (Fe) for Point-of-Care Testing of Butyrylcholinesterase Activity Using a Portable High-Throughput Photothermal Device
Guo_2020_BMC.Musculoskelet.Disord_21_547Correlation analysis between CARMEN variants and alcohol-induced osteonecrosis of the femoral head in the Chinese population
Guo_2020_Biochem.Biophys.Res.Commun_524_784Structural and functional insights into the Asp1/2/3 complex mediated secretion of pneumococcal serine-rich repeat protein PsrP
Guo_2020_Compr.Rev.Food.Sci.Food.Saf_19_759Synthesis, physicochemical properties, and health aspects of structured lipids: A review
Guo_2020_Curr.Microbiol_77_273Characterization and Genome Analysis of a Zearalenone-Degrading Bacillus velezensis Strain ANSB01E
Guo_2020_Curr.Protoc.Immunol_131_e107Inflammasome Assays In Vitro and in Mouse Models
Guo_2020_Molecules_25_Design, Synthesis, and Evaluation of Acetylcholinesterase and Butyrylcholinesterase Dual-Target Inhibitors against Alzheimer's Diseases
Guo_2020_Undersea.Hyperb.Med_47_181Hyperbaric oxygen therapy may be effective to improve hypoxemia in patients with severe COVID-2019 pneumonia: two case reports
Guo_2020_Viruses_12_A Conserved Carboxylesterase Inhibits Tobacco mosaic virus (TMV) Accumulation in Nicotiana benthamiana Plants
Gurbuz_2020_Turk.J.Pediatr_62_831A rare cause of hepatomegaly and dyslipidemia: lysosomal acid lipase deficiency
Gururaj_2020_Prep.Biochem.Biotechnol__1Production, purification and application of Cutinase in enzymatic scouring of cotton fabric isolated from Acinetobacter baumannii AU10
Gutierrez_2020_Mol.Inform__Aporphinoid alkaloids derivatives as selective cholinesterases inhibitors: biological evaluation and docking study
Guven_2020_J.Pediatr.Gastroenterol.Nutr_70_e114Effectivity of Pancreatic Enzyme Replacement Therapy in Malnourished Children
Guzel_2020_J.Biomol.Struct.Dyn__1Phthalocyanine complexes with (4-isopropylbenzyl)oxy substituents: preparation and evaluation of anti-carbonic anhydrase, anticholinesterase enzymes and molecular docking studies
Gwozdzinski_2020_Cardiol.Res.Pract_2020_6478785Alterations in the Properties of Red Blood Cells in Men with Coronary Artery Diseases after Comprehensive Cardiac Rehabilitation
Gyimah_2020_Environ.Sci.Pollut.Res.Int__Sublethal concentrations of triclosan elicited oxidative stress, DNA damage, and histological alterations in the liver and brain of adult zebrafish
Ha_2020_Curr.Protein.Pept.Sci_21_99Butyrylcholinesterase: A Multifaceted Pharmacological Target and Tool
Haake_2020_Expert.Opin.Drug.Saf__An update on the utility and safety of cholinesterase inhibitors for the treatment of Alzheimer's disease
Habacha_2020_Tunis.Med_98_123Toxin-induced cardiac arrest: frequency, causative agents, management and hospital outcome
Hadas_2020_JCI.Insight_5_Hyaluronan control of the primary vascular barrier during early mouse pregnancy is mediated by uterine NK cells
Hafiz_2020_Molecules_25_Inhibitory Effects of Raw-Extract Centella asiatica (RECA) on Acetylcholinesterase, Inflammations, and Oxidative Stress Activities via In Vitro and In Vivo
Haghighijoo_2020_Bioorg.Chem_103_104146N-Cyclohexylimidazo[1,2-a]pyridine derivatives as multi-target-directed ligands for treatment of Alzheimer's disease
Hahn_2020_Pharmacol.Biochem.Behav__173043Evidence for positive allosteric modulation of cognitive-enhancing effects of nicotine by low-dose galantamine in rats
Hahn_2020_Psychopharmacology.(Berl)_237_219Evidence for positive allosteric modulation of cognitive-enhancing effects of nicotine in healthy human subjects
Haider_2020_PLoS.One_15_e0227631Naringenin protects AlCl3/D-galactose induced neurotoxicity in rat model of AD via attenuation of acetylcholinesterase levels and inhibition of oxidative stress
Hails_2020_Appl.Microbiol.Biotechnol_104_7521A novel lecithin:cholesterol acyltransferase for soybean oil refining provides higher yields and extra nutritional value with a cleaner process
Hamada-Ode_2020_Rheumatol.Adv.Pract_4_rkaa031Is serum cholinesterase level a predictor of the extent of organ involvement in immunoglobulin G4-related disease?
Hamer_2020_Ann.Med.Surg.(Lond)_56_169Retrospective cohort study demonstrates that modified CT Severity Index directly correlates with lipase values at or above 600
Hamid-Adiamoh_2020_Malar.J_19_314Insecticide resistance in indoor and outdoor-resting Anopheles gambiae in Northern Ghana
Hammock_2020_Am.J.Pathol_190_1782Eicosanoids: The Overlooked Storm in Coronavirus Disease 2019 (COVID-19)?
Hamzaoui_2020_Front.Mol.Biosci_7_604042Soluble Epoxide Hydrolase Inhibition Prevents Experimental Type 4 Cardiorenal Syndrome
Han_2020_Adv.Exp.Med.Biol_1266_39Stem Cell Therapy for Alzheimer's Disease
Han_2020_Bioorg.Chem_96_103646Protein tyrosine phosphatase 1B (PTP1B) inhibitorsfrom the deep-sea fungus Penicillium chrysogenum SCSIO 07007
Han_2020_Eur.J.Med.Chem__113028Ligand-based optimization to identify novel 2-aminobenzo[d]thiazole derivatives as potent sEH inhibitors with anti-inflammatory effects
Han_2020_FEBS.Open.Bio_10_2375Combined use of irinotecan and p53 activator enhances growth inhibition of mesothelioma cells
Han_2020_Mol.Cell.Endocrinol__111122RORalpha regulates hepatic lipolysis by inducing transcriptional expression of PNPLA3 in mice
Hanif_2020_Mol.Cell.Biochem_465_37Ephx2-gene deletion affects acetylcholine-induced relaxation in angiotensin-II infused mice: role of nitric oxide and CYP-epoxygenases
Hanna_2020_JAMA.Neurol_77_225Selective Vulnerability of the Nucleus Basalis of Meynert Among Neuropathologic Subtypes of Alzheimer Disease
Hannon_2020_Lifestyle.Genom__1Genetic Variants in Lipid Metabolism Pathways Interact with Diet to Influence Blood Lipid Concentrations in Adults with Overweight and Obesity
Hansen_2020_Mil.Med__Pyridostigmine Impairs Pulmonary Function in Asthmatic Subjects: Reanalysis of Results From an Observational Study
Hansen_2020_Occup.Environ.Med_77_713Exposure to cholinesterase inhibiting insecticides and blood glucose level in a population of Ugandan smallholder farmers
Hansiya_2020_J.Ethnopharmacol__113687In vitro anti-venom potential of various solvent based leaf extracts of Andrographis serpyllifolia (Rottler ex Vahl) Wight against Naja naja and Daboia russelli
Hantke_2020_Chem.Commun.(Camb)_56_2925Evidence for enzyme catalysed intramolecular [4+2] Diels-Alder cyclization during the biosynthesis of pyrichalasin H
Hanumanthappa_2020_Comb.Chem.High.Throughput.Screen__In silico and in vivo evaluation of oxidative stress inhibitors against Parkinson's disease using the C. elegans model
Haq_2020_Plant.Physiol.Biochem_152_72Tobacco SABP2-interacting protein SIP428 is a SIR2 type deacetylase
Haque_2020_Mar.Pollut.Bull_156_111276Exposure to sublethal concentrations of zinc pyrithione inhibits growth and survival of marine polychaete through induction of oxidative stress and DNA damage
Hardos_2020_Aerosp.Med.Hum.Perform_91_710Cholinesterase Inhibition and Exposure to Organophosphate Esters in Aircraft Maintenance Workers
Harrison_2020_Bioorg.Med.Chem.Lett__127560Discovery of a Series of Ester-substituted NLRP3 Inflammasome Inhibitors
Hashemzaei_2020_Phytother.Res__A review on pain-relieving activity of berberine
Hashmi_2020_Bioorg.Chem_107_104554Probing 4-(diethylamino)-salicylaldehyde-based thiosemicarbazones as multi-target directed ligands against cholinesterases, carbonic anhydrases and alpha-glycosidase enzymes
Hassan_2020_J.Toxicol_2020_8815313Biochemical Constituent of Ginkgo biloba (Seed) 80% Methanol Extract Inhibits Cholinesterase Enzymes in Javanese Medaka (Oryzias javanicus) Model
Hassani_2020_Mol.Autism_11_85Targeting of delta-catenin to postsynaptic sites through interaction with the Shank3 N-terminus
Hayashi_2020_J.Biomed.Sci_27_29Effects of neural stem cell transplantation in Alzheimer's disease models
Hayes_2020_Ann.N.Y.Acad.Sci__Positron emission tomography evaluation of oxime countermeasures in live rats using the tracer O-(2-[(18) F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate [(18) F]-VXS
Hazard_2020_BMC.Fam.Pract_21_161A top 5 list for French general practice
He_2020_Ann.Palliat.Med_9_3436Acupuncture of the Beishu acupoint participates in regulatory effects of ginsenoside Rg1 on T cell subsets of rats with chronic fatigue syndrome
He_2020_Food.Sci.Nutr_8_2234Separation of saturated fatty acids from docosahexaenoic acid-rich algal oil by enzymatic ethanolysis in tandem with molecular distillation
He_2020_Insects_11_Low Mismatch Rate between Double-Stranded RNA and Target mRNA Does Not Affect RNA Interference Efficiency in Colorado Potato Beetle
He_2020_Int.J.Biol.Macromol__Natural soluble epoxide hydrolase inhibitors from Inula helenium and their interactions with soluble epoxide hydrolase
He_2020_Mol.Ther.Oncolytics_17_83miR-140-3p Inhibits Cutaneous Melanoma Progression by Disrupting AKT/p70S6K and JNK Pathways through ABHD2
He_2020_Pestic.Biochem.Physiol_163_227Molecular characterization and functional analysis of a novel candidate of cuticle carboxylesterase in Spodoptera exigua degradating sex pheromones and plant volatile esters
Heard_2020_J.Antibiot.(Tokyo)_73_803Discovery and characterization of a cytochalasan biosynthetic cluster from the marine-derived fungus Aspergillus flavipes CNL-338
Heater_2020_J.Am.Chem.Soc__In Vivo Enzyme Entrapment in a Protein Crystal
Hedges_2020_Xenobiotica__1Metabolism of bifenthrin, beta-cyfluthrin, -cyhalothrin, cyphenothrin and esfenvalerate by rat and human cytochrome P450 and carboxylesterase enzymes
Hefke_2020_ACS.Med.Chem.Lett_11_1244Computer-Aided Fragment Growing Strategies to Design Dual Inhibitors of Soluble Epoxide Hydrolase and LTA4 Hydrolase
Heikkinen_2020_Anat.Rec.(Hoboken)_303_1653Collagen XIII and Other ECM Components in the Assembly and Disease of the Neuromuscular Junction
Hemmerich_2020_Microb.Biotechnol_13_2020Screening of a genome-reduced Corynebacterium glutamicum strain library for improved heterologous cutinase secretion
Henao_2020_Toxins.(Basel)_12_Polymethoxy-1-Alkenes Screening of Chlorella and Spirulina Food Supplements Coupled with In Vivo Toxicity Studies
Heo_2020_Proteins_88_637High-accuracy protein structures by combining machine-learning with physics-based refinement
Heo_2020_Sci.Rep_10_21695Acetylcholinesterase and butyrylcholinesterase inhibitory activities of khellactone coumarin derivatives isolated from Peucedanum japonicum Thurnberg
Her_2020_Drug.Metab.Dispos_48_230Carboxylesterase 1 and Precision Pharmacotherapy: Pharmacogenetics and Nongenetic Regulators
Herbert_2020_Chemosphere__129107Acute neurotoxicity evaluation of two anticholinesterasic insecticides, independently and in mixtures, and a neonicotinoid on a freshwater gastropod
Hernandez-Toledano_2020_Mutat.Res_856-857_503233Genotoxicity of the organophosphate pesticide malathion and its metabolite dimethylthiophosphate in human cells in vitro
Heshmati_2020_J.Neurosci_40_6228Depression and Social Defeat Stress Are Associated with Inhibitory Synaptic Changes in the Nucleus Accumbens
Heysieattalab_2020_Neurochem.Res__Effects of Delphinidin on Pathophysiological Signs of Nucleus Basalis of Meynert Lesioned Rats as Animal Model of Alzheimer Disease
Hicks_2020_Int.J.Environ.Res.Public.Health_17_Census Demographics and Chlorpyrifos Use in California's Central Valley, 2011-15: A Distributional Environmental Justice Analysis
Hiesinger_2020_ACS.Med.Chem.Lett_11_298Design of Dual Inhibitors of Soluble Epoxide Hydrolase and LTA4 Hydrolase
Hiesinger_2020_J.Med.Chem_63_11498Design, Synthesis, and Structure-Activity Relationship Studies of Dual Inhibitors of Soluble Epoxide Hydrolase and 5-Lipoxygenase
Hildreth_2020_J.Nutr.Biochem__108484Cytochrome P450-derived linoleic acid metabolites EpOMEs and DiHOMEs: A review of recent studies
Hindmarsh_2020_J.Palliat.Med__Glycopyrrolate and the Management of Death Rattle in Patients with Myasthenia Gravis
Hines_2020_mSphere_5_Lipidomic and Ultrastructural Characterization of the Cell Envelope of Staphylococcus aureus Grown in the Presence of Human Serum
Hinojosa_2020_Ecotoxicol.Environ.Saf_191_110222In vitro assessment of the combination of cylindrospermopsin and the organophosphate chlorpyrifos on the human neuroblastoma SH-SY5Y cell line
Hiraiwa_2020_J.Cardiol__Usefulness of the plasma branched-chain amino acid/aromatic amino acid ratio for predicting future cardiac events in patients with heart failure
Hirata_2020_Nat.Commun_11_3820Associations of cardiovascular biomarkers and plasma albumin with exceptional survival to the highest ages
Hirayama_2020_Mol.Pharm__Identification of the uptake transporter responsible for distribution of acotiamide into stomach tissue
Hirokawa_2020_Ann.Surg.Oncol_27_4143Is Postoperative Adjuvant Transcatheter Arterial Infusion Therapy Effective for Patients with Hepatocellular Carcinoma who Underwent Hepatectomy? A Prospective Randomized Controlled Trial
Hoang_2020_Pharm.Biol_58_1098Effects of Hippeastrum reticulatum on memory, spatial learning and object recognition in a scopolamine-induced animal model of Alzheimer's disease
Hoch_2020_Cell.Chem.Biol_27_586Combined Omics Approach Identifies Gambogic Acid and Related Xanthones as Covalent Inhibitors of the Serine Palmitoyltransferase Complex
Hoffmann_2020_ISME.J__Diversity and metabolism of Woeseiales bacteria, global members of marine sediment communities
Hofmann_2020_Chemistry_26_7299Sterubin: Enantioresolution and Configurational Stability, Enantiomeric Purity in Nature, and Neuroprotective Activity in Vitro and in Vivo
Hogan_2020_Cureus_12_e9760Acute Myasthenia Crisis: A Critical Emergency Department Differential
Hollingsworth_2020_Biorxiv__DPP9 directly sequesters the NLRP1 C-terminus to repress inflammasome activation
Homayoonzadeh_2020_J.Econ.Entomol_113_2864Micronutrient Fertilization of Greenhouse Cucumbers Mitigates Pirimicarb Resistance in Aphis gossypii (Hemiptera: Aphididae)
Hon_2020_Nucleic.Acids.Res__EnzymeMiner: automated mining of soluble enzymes with diverse structures, catalytic properties and stabilities
Hong_2020_Environ.Toxicol__DNA damage, immunotoxicity, and neurotoxicity induced by deltamethrin on the freshwater crayfish, Procambarus clarkii
Hong_2020_J.Neurosci__Structural remodeling of active zones is associated with synaptic homeostasis
Hoover_2020_Int.Immunopharmacol_81_106359Cholinergic leukocytes in sepsis and at the neuroimmune junction in the spleen
Horio_2020_J.Vet.Med.Sci__Immunohistochemical analysis for acetylcholinesterase and choline acetyltransferase in mouse cerebral cortex after traumatic brain injury
Horkowitz_2020_Immunotargets.Ther_9_333Acetylcholine Regulates Pulmonary Pathology During Viral Infection and Recovery
Horvath_2020_J.Alzheimers.Dis__Patients with Alzheimer's Disease Have Increased Levels of Insulin-like Growth Factor-I in Serum but not in Cerebrospinal Fluid
Hou_2020_Biomed.Res.Int_2020_5370759Dipeptidyl Peptidase-4 Is a Target Protein of Epigallocatechin-3-Gallate
Hou_2020_Fitoterapia__104628Tunicyclin L, a cyclic peptide from Psammosilene tunicoides: Isolation, characterization, conformational studies and biological activity
Hour_2020_J.Control.Release__Magnetic targeted delivery of the SPIONs-labeled mesenchymal stem cells derived from human Wharton's jelly in Alzheimer's rat models
Hrvat_2020_Arh.Hig.Rada.Toksikol_71_266Counteracting poisoning with chemical warfare nerve agents
Hu_2020_Chem.Commun.(Camb)__Manipulating regioselectivity of an epoxide hydrolase for single enzymatic synthesis of (R)-1,2-diols from racemic epoxides
Hu_2020_Ecotoxicol.Environ.Saf_205_111141A novel esterase LanE from Edaphocola flava HME-24 and the enantioselective degradation mechanism of herbicide lactofen
Hu_2020_Front.Genet_11_524258Multiple Rare Risk Coding Variants in Postsynaptic Density-Related Genes Associated With Schizophrenia Susceptibility
Hu_2020_Front.Pharmacol_11_1045Shexiang Baoxin Pill, a Traditional Chinese Herbal Formula, Rescues the Cognitive Impairments in APP/PS1 Transgenic Mice
Hu_2020_Int.J.Biol.Macromol_147_1213Near-perfect kinetic resolution of racemic p-chlorostyrene oxide by SlEH1, a novel epoxide hydrolase from Solanum lycopersicum with extremely high enantioselectivity
Hu_2020_J.Environ.Sci.Health.B__1Development of enzymatic electrochemical biosensors for organophosphorus pesticide detection
Hu_2020_J.Neuroimmune.Pharmacol_15_538HIV-1 Tat-Induced Astrocytic Extracellular Vesicle miR-7 Impairs Synaptic Architecture
Hu_2020_Plant.Sci_290_110314Subcellular localization of chlorophyllase2 reveals it is not involved in chlorophyll degradation during senescence in Arabidopsis thaliana
Huang_2020_Angew.Chem.Int.Ed.Engl_59_4349Collaborative Biosynthesis of a Class of Bioactive Azaphilones by Two Separate Gene Clusters Containing Four PKS/NRPSs with Transcriptional Crosstalk in Fungi
Huang_2020_Ann.Transl.Med_8_746Pharmacological treatment of neuropsychiatric symptoms of dementia: a network meta-analysis protocol
Huang_2020_Bioengineered_11_375Improved production of recombinant Rhizomucor miehei lipase by coexpressing protein folding chaperones in Pichia pastoris, which triggered ER stress
Huang_2020_Food.Chem_326_126785Antioxidant and pancreatic lipase inhibitory effects of flavonoids from different citrus peel extracts: An in vitro study
Huang_2020_Food.Chem__128407Rhizomucor miehei lipase-catalysed synthesis of cocoa butter equivalent from palm mid-fraction and stearic acid: Characteristics and feasibility as cocoa butter alternative
Huang_2020_Food.Funct_11_5607Pediococcus pentosaceus B49 from human colostrum ameliorates constipation in mice
Huang_2020_Front.Mol.Neurosci_13_154Gene Expression Profile at the Motor Endplate of the Neuromuscular Junction of Fast-Twitch Muscle
Huang_2020_Int.J.Biol.Macromol_164_1927Inhibitory mechanisms and interaction of tangeretin, 5-demethyltangeretin, nobiletin, and 5-demethylnobiletin from citrus peels on pancreatic lipase: Kinetics, spectroscopies, and molecular dynamics simulation
Huang_2020_Int.J.Pharm__120182Nose-to-brain delivery of drug nanocrystals by using Ca(2+) responsive deacetylated gellan gum based in situ-nanogel
Huang_2020_J.Biomed.Sci_27_18Clinical trials of new drugs for Alzheimer disease
Huang_2020_J.Biosci.Bioeng_129_588Characterization of a novel carboxylesterase from Bacillus velezensis SYBC H47 and its application in degradation of phthalate esters
Huang_2020_J.Med.Chem_63_7052Identification of Highly Selective Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitors by a Covalent Fragment-Based Approach
Huang_2020_J.Sci.Food.Agric_100_4565Lipase catalysis of alpha-linolenic acid-rich medium- and long-chain triacylglycerols from perilla oil and medium-chain triacylglycerols with reduced by-products
Huang_2020_Med.Res.Rev_40_79Lipoprotein-associated phospholipase A2: The story continues
Huang_2020_Pediatrics__Early Use of Blood Purification in Severe Epstein-Barr Virus-Associated Hemophagocytic Syndrome
Huang_2020_Pest.Manag.Sci_76_534Chemical composition and larvicidal activity against Aedes mosquitoes of essential oils from Arisaema fargesii
Huang_2020_Pharmacol.Res.Perspect_8_e00622Comparative risk of cardiac arrhythmias associated with acetylcholinesterase inhibitors used in treatment of dementias - A narrative review
Huang_2020_Phytochemistry_178_112459Diterpenoid alkaloids from Aconitum anthoroideum that offer protection against MPP(+)-Induced apoptosis of SH-SY5Y cells and acetylcholinesterase inhibitory activity
Huang_2020_Phytochemistry_182_112597(+/-)-Dievodialetins A-G: Seven pairs of enantiomeric coumarin dimers with anti-acetylcholinesterase activity from the roots of Evodia lepta Merr
Hudcova_2020_Molecules_25_Arylaminopropanone Derivatives as Potential Cholinesterase Inhibitors: Synthesis, Docking Study and Biological Evaluation
Hufnagel_2020_Nat.Commun_11_492High-quality genome sequence of white lupin provides insight into soil exploration and seed quality
Hunt_2020_Ann.Pharmacother__1060028020929061Effects on Postoperative Gastrointestinal Motility After Neuromuscular Blockade Reversal With Sugammadex Versus Neostigmine/Glycopyrrolate in Colorectal Surgery Patients
Hunt_2020_Cancers.(Basel)_12_Interrupting Neuron-Tumor Interactions to Overcome Treatment Resistance
Huo_2020_Bioorg.Med.Chem__115853Design, synthesis and biological evaluation of novel chalcone-like compounds as potent and reversible pancreatic lipase inhibitors
Huo_2020_Eur.J.Med.Chem_209_112856Design, synthesis and biological evaluation of indanone-chalcone hybrids as potent and selective hCES2A inhibitors
Huo_2020_Plant.Physiol_184_1438IRREGULAR POLLEN EXINE2 Encodes a GDSL Lipase Essential for Male Fertility in Maize
Huseynova_2020_J.Biomol.Struct.Dyn__1Design, synthesis, characterization, biological evaluation, and molecular docking studies of novel 1,2-aminopropanthiols substituted derivatives as selective carbonic anhydrase, acetylcholinesterase and alpha-glycosidase enzymes inhibitors
Hussain_2020_Biomolecules_10_4-Benzyloxylonchocarpin and Muracatanes A-C from Ranunculus muricatus L. and Their Biological Effects
Hussein_2020_Heliyon_6_e05678Neuroprotective activity of Ulmus pumila L. in Alzheimer's disease in rats; role of neurotrophic factors
Huyer_2020_CMAJ_192_E422Five-year risk of admission to long-term care home and death for older adults given a new diagnosis of dementia: a population-based retrospective cohort study
Hv_2020_SAGE.Open.Med_8_2050312120973499Kinetics and computational analysis of cholinesterase inhibition by REVERC3, a bisdemethoxycurcumin-rich Curcuma longa extract: Relevance to the treatment of Alzheimer's disease
Hwang_2020_Food.Sci.Biotechnol_29_987Enzymatic hydrolysis of perilla seed meal yields water-soluble dietary fiber as a potential functional carbohydrate source
Hwang_2020_Foods_9_Assessment of Physicochemical Quality, Antioxidant Content and Activity, and Inhibition of Cholinesterase between Unripe and Ripe Blueberry Fruit
Hwang_2020_Nutrients_12_Biological and Computational Studies for Dual Cholinesterases Inhibitory Effect of Zerumbone
Ibi_2020_Circ.Genom.Precis.Med_13_e002693Genome-Wide Association Study of the Postprandial Triglyceride Response Yields Common Genetic Variation in LIPC (Hepatic Lipase)
Ibrahim_2020_Int.J.Biol.Macromol__The dipeptidyl peptidase IV inhibitory activity and multifunctional antidiabetic properties of SQSPA: Structure - Activity analysis evaluated with alanine scanning
Ibrahim_2020_Invert.Neurosci_20_16Glial cells in the posterior sub-esophageal mass of the brain in Sepia officinalis (Linnaeus, 1758) (decapodiformes-sepiida): ultrastructure and cytochemical studies
Ibrahim_2020_Neurotox.Res__Quercetin Attenuates the Oxidative Injury-Mediated Upregulation of Apoptotic Gene Expression and Catecholaminergic Neurotransmitters of the Fetal Rats' Brain Following Prenatal Exposure to Fenitrothion Insecticide
Ichikawa_2020_Appl.Biochem.Biotechnol_192_910Biochemical Characterization of a Lipolytic Enzyme From Aspergillus oryzae That Hydrolyzes Triacylglycerol and Sterol Esters
Ichu_2020_Biochemistry__ABHD12 and LPCAT3 Interplay Regulates a Lyso-phosphatidylserine-C20:4 Phosphatidylserine Lipid Network Implicated in Neurological Disease
Igartua_2020_AAPS.PharmSciTech_21_110Combined Therapy for Alzheimer's Disease: Tacrine and PAMAM Dendrimers Co-Administration Reduces the Side Effects of the Drug without Modifying its Activity
Iheanacho_2020_Biomarkers__1Biomarkers of neurotoxicity, oxidative stress, hepatotoxicity and lipid peroxidation in Clarias gariepinus exposed to melamine and polyvinyl chloride
Iheanacho_2020_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__108741Neurotoxicity, oxidative stress biomarkers and haematological responses in African catfish (Clarias gariepinus) exposed to polyvinyl chloride microparticles
Iijima_2020_Sci.Rep_10_15256Esterified carotenoids are synthesized in petals of carnation (Dianthus caryophyllus) and accumulate in differentiated chromoplasts
Ijomone_2020_Hum.Exp.Toxicol__960327120946477Neurotoxicity in pre-eclampsia involves oxidative injury, exacerbated cholinergic activity and impaired proteolytic and purinergic activities in cortex and cerebellum
Ikeda_2020_J.Biochem_168_643Involvement of PP2A methylation in the adipogenic differentiation of bone marrow-derived mesenchymal stem cell
Ikram_2020_Antioxidants.(Basel)_9_Antioxidant and Neuroprotective Effects of Caffeine against Alzheimer's and Parkinson's Disease: Insight into the Role of Nrf-2 and A2AR Signaling
Imai_2020_J.Pharm.Sci_109_1417Effect of Calcium on the Hydrolysis Activity of Human Butyrylcholinesterase
Imig_2020_Front.Pharmacol_11_598858Editorial: Clinical Paths for Soluble Epoxide Hydrolase Inhibitors
Imig_2020_Hypertension__HYPERTENSIONAHA12013898Epoxy Fatty Acids: From Salt Regulation to Kidney and Cardiovascular Therapeutics: 2019 Lewis K. Dahl Memorial Lecture
Imran_2020_Front.Nutr_7_587367Grewia asiatica Berry Juice Diminishes Anxiety, Depression, and Scopolamine-Induced Learning and Memory Impairment in Behavioral Experimental Animal Models
Inayat_2020_Sleep_43_Low acetylcholine during early sleep is important for motor memory consolidation
Indapurkar_2020_J.Anal.Toxicol__A Method for Diagnosing Organophosphate Pesticide Exposure in Humans using Liquid Chromatography Coupled Tandem Mass Spectrometry
Iqbal_2020_Pak.J.Pharm.Sci_33_149BSA Binding, molecular docking and in vitro biological screening of some new 1, 2, 4-triazole heterocycles bearing azinane nucleus
Iraji_2020_Bioorg.Chem_97_103649Novel small molecule therapeutic agents for Alzheimer disease: Focusing on BACE1 and multi-target directed ligands
Irungbam_2020_Lab.Invest_100_454Cannabinoid receptor 1 knockout alleviates hepatic steatosis by downregulating perilipin 2
Isenberg_2020_J.Appl.Lab.Med_5_273The Effects of Gamma Irradiation on Chemical Biomarker Recovery from Mixed Chemical/Biological Threat Exposure Specimens
Ishak_2020_Molecules_25_3430Ion-Pair Interaction and Hydrogen Bonds as Main Features of Protein Thermostability in Mutated T1 Recombinant Lipase Originating from Geobacillus zalihae
Ishaq_2020_Bioorg.Chem_100_103924Synthesis, bioactivity and binding energy calculations of novel 3-ethoxysalicylaldehyde based thiosemicarbazone derivatives
Ishimota_2020_J.Environ.Sci.Health.B__1Rapid adaptation of Chironomus yoshimatsui to acetylcholinesterase inhibitors (pyraclofos and pirimicarb) in a multi-generation study
Ishola_2020_Drug.Metab.Pers.Ther__Rutin ameliorates scopolamine-induced learning and memory impairments through enhancement of antioxidant defense system and cholinergic signaling
Ishola_2020_Fundam.Clin.Pharmacol__Novel potential of metformin on valproic acid-induced autism spectrum disorder in rats: involvement of antioxidant defense system
Ishola_2020_Neurotox.Res_37_58Diastereomeric Mixture of Calophyllic and Isocalophyllic Acid Ameliorates Scopolamine-Induced Memory Impairment in Mice: Involvement of Antioxidant Defense and Cholinergic Systems
Isik_2020_Alzheimer.Dis.Assoc.Disord_34_339Cardiac and Blood Pressure Safety of Transdermal Rivastigmine in Elderly Patients With Dementia With Lewy Bodies
Isik_2020_Arch.Pharm.(Weinheim)__e2000102Synthesis, characterization, biological evaluation, and in silico studies of novel 1,3-diaryltriazene-substituted sulfathiazole derivatives
Isik_2020_J.Biomol.Struct.Dyn__1The impact of some phenolic compounds on serum acetylcholinesterase: kinetic analysis of an enzyme/inhibitor interaction and molecular docking study
Ismail_2020_J.Med.Entomol_57_204The Effect of Entomopathogenic Fungi on Enzymatic Activity in Chlorpyrifos-Resistant Mosquitoes, Culex quinquefasciatus (Diptera: Culicidae)
Ismail_2020_Molecules_25_Therapeutic Uses of Red Macroalgae
Istrefi_2020_Arch.Pharm.(Weinheim)__e1900383Sulfonamides incorporating ketene N,S-acetal bioisosteres as potent carbonic anhydrase and acetylcholinesterase inhibitors
Iturbe-Requena_2020_Chemosphere_242_125293Acute oral and contact toxicity of new ethyl-carbamates on the mortality and acetylcholinesterase activity of honey bee (Apis mellifera)
Ivy_2020_Neuropsychopharmacology__Cannabinoid CB2 receptors mediate the anxiolytic-like effects of monoacylglycerol lipase inhibition in a rat model of predator-induced fear
Jabir_2020_J.Biomol.Struct.Dyn__1In silico screening of glycogen synthase kinase-3beta targeted ligands against acetylcholinesterase and its probable relevance to Alzheimer's disease
Jabloune_2020_Microbes.Environ_35_Enzymatic Degradation of p-Nitrophenyl Esters, Polyethylene Terephthalate, Cutin, and Suberin by Sub1, a Suberinase Encoded by the Plant Pathogen Streptomyces scabies
Jabri_2020_Nutr.Neurosci__1Chamomile decoction mitigates high fat diet-induced anxiety-like behavior, neuroinflammation and cerebral ROS overload
Jacobs_2020_Neurologist_25_1Myasthenia Gravis Crisis and Atrial Fibrillation
Jager_2020_Eur.Neuropsychopharmacol_30_5Cortical control of aggression: GABA signalling in the anterior cingulate cortex
Jahangirian_2020_Int.J.Nanomedicine_15_2935Enzymatic Synthesis of Ricinoleyl Hydroxamic Acid Based on Commercial Castor Oil, Cytotoxicity Properties and Application as a New Anticancer Agent
Jain_2020_Bioorg.Chem_103_104151Design, synthesis and biological evaluation of triazole-oxadiazole conjugates for the management of cognitive dysfunction
Jain_2020_J.Exp.Biol__Sex-specific molecular specialization and activity rhythm dependent gene expression in honey bee antennae
Jaiswal_2020_J.Biochem.Mol.Toxicol__e22575Effect of hesperidin on fluoride-induced neurobehavioral and biochemical changes in rats
Jaiswal_2020_J.Cancer.Res.Ther_16_S39Butyrylcholinesterase: An economical marker of disease activity in oral squamous cell carcinoma before and after therapy
Jamal_2020_Curr.Pharm.Des__A computational study of natural compounds from Bacopa monnieri in the treatment of Alzheimer's disease
James_2020_Soc.Psychiatry.Psychiatr.Epidemiol__Treatment pathway analysis of newly diagnosed dementia patients in four electronic health record databases in Europe
Jamieson_2020_Front.Physiol_11_48Age and Sex Differences in Hearts of Soluble Epoxide Hydrolase Null Mice
Jamil_2020_Front.Plant.Sci_11_434A New Series of Carlactonoic Acid Based Strigolactone Analogs for Fundamental and Applied Research
Jamir_2020_Int.J.Biol.Macromol_163_2429ZCPG, a cysteine protease from Zingiber montanum rhizome exhibits enhanced anti-inflammatory and acetylcholinesterase inhibition potential
Jan_2020_Acta.Clin.Belg__1The management of dementia by flemish GPs: it remains a difficult job
Janatunaim_2020_Recent.Pat.Biotechnol_14_229Construction and cloning of Plastic-Degrading Recombinant Enzymes (MHETase)
Jang_2020_World.J.Clin.Cases_8_5341Donepezil-related inadequate neuromuscular blockade during laparoscopic surgery: A case report
Jangra_2020_Neurochem.Res__Amelioration of Repeated Restraint Stress-Induced Behavioral Deficits and Hippocampal Anomalies with Taurine Treatment in Mice
Janicki_2020_Bioorg.Chem_94_103377The first enzyme-promoted addition of nitromethane to imines (aza-Henry reaction)
Janowska_2020_Toxicol.In.Vitro__104794Mitochondrial respiratory chain complex I dysfunction induced by N-methyl carbamate ex vivo can be alleviated with a cell-permeable succinate prodrug Carbamate toxicity and treatment
Jara-Palacios_2020_Antioxidants.(Basel)_9_Extraction of Antioxidants from Winemaking Byproducts: Effect of the Solvent on Phenolic Composition, Antioxidant and Anti-Cholinesterase Activities, and Electrochemical Behaviour
Jee_2020_Int.J.Mol.Sci_21_Neuroprotective Effect of Cudrania tricuspidata Fruit Extracts on Scopolamine-Induced Learning and Memory Impairment
Jee_2020_Proc.Natl.Acad.Sci.U.S.A_117_29435Master curve of boosted diffusion for 10 catalytic enzymes
Jeong_2020_Chem.Pharm.Bull.(Tokyo)_68_1155Novel Hybrid Molecules Based on (-)-Epigallocatechin Gallate as Potent Anti-adipogenic Agents
Jeong_2020_ChemMedChem_15_2257Selected 1,3-Benzodioxine-Containing Chalcones as Multipotent Oxidase and Acetylcholinesterase Inhibitors
Jeong_2020_J.Microbiol.Biotechnol__Phenolic Profiles of Hardy Kiwifruits and Their Neuroprotective Effects on PC-12 and SH-SY5Y Cells against Oxidative Stress
Jeong_2020_Molecules_25_Inhibition of Butyrylcholinesterase and Human Monoamine Oxidase-B by the Coumarin Glycyrol and Liquiritigenin Isolated from Glycyrrhiza uralensis
Jett_2020_Crit.Rev.Toxicol__1A national toxicology program systematic review of the evidence for long-term effects after acute exposure to sarin nerve agent
Jett_2020_Neurobiol.Dis_133_104335Translational research on chemical nerve agents
Jha_2020_Molecules_26_Discovery of Monoacylglycerol Lipase (MAGL) Inhibitors Based on a Pharmacophore-Guided Virtual Screening Study
Ji_2020_Environ.Pollut_264_114747Tricresyl phosphate isomers exert estrogenic effects via G protein-coupled estrogen receptor-mediated pathways
Ji_2020_Int.J.Biol.Macromol__Protective effects of chondroitin sulphate nano-selenium on a mouse model of Alzheimer's disease
Jia_2020_Environ.Toxicol__Single and combined effects of carbamazepine and copper on nervous and antioxidant systems of zebrafish (Danio rerio)
Jian_2020_Adv.Industrial.Eng.Polym.Res_3_19An overview on synthesis, properties and applications of poly(butylene-adipate-co-terephthalate)-PBAT
Jiang_2020_Bioorg.Med.Chem_30_115940Discovery of potent glycogen synthase kinase 3/cholinesterase inhibitors with neuroprotection as potential therapeutic agent for Alzheimer's disease
Jiang_2020_Cell.Death.Dis_11_385Inhibition of soluble epoxide hydrolase attenuates renal tubular mitochondrial dysfunction and ER stress by restoring autophagic flux in diabetic nephropathy
Jiang_2020_Eur.J.Med.Chem_207_112751Rational design and biological evaluation of a new class of thiazolopyridyl tetrahydroacridines as cholinesterase and GSK-3 dual inhibitors for Alzheimer's disease
Jiang_2020_Eur.J.Pharmacol_868_172874Inhibition of soluble epoxide hydrolase attenuates airway remodeling in a chronic asthma model
Jiang_2020_Fitoterapia__104477Fifteen new diterpenoid alkaloids from the roots of Aconitum kirinense Nakai
Jiang_2020_Int.J.Toxicol__1091581819898396Toxicity Assessment of 4 Azo Dyes in Zebrafish Embryos
Jiang_2020_PLoS.One_15_e0232747Toxicological and biochemical analyses demonstrate no toxic effect of Bt maize on the Folsomia candida
Jiao_2020_Environ.Pollut_257_113517Monobutyl phthalate (MBP) can dysregulate the antioxidant system and induce apoptosis of zebrafish liver
Jiaojiao_2020_Bioprocess.Biosyst.Eng_43_293Acetylcholinesterase biosensors based on ionic liquid functionalized carbon nanotubes and horseradish peroxidase for monocrotophos determination
Jin_2020_Anal.Chim.Acta_1100_215A facile microfluidic paper-based analytical device for acetylcholinesterase inhibition assay utilizing organic solvent extraction in rapid detection of pesticide residues in food
Jin_2020_J.Biomol.Struct.Dyn__1Synthesis, Biological Activity, Molecular Docking Studies of a Novel Series of 3-Aryl-7H-thiazolo[3,2-b]-1,2,4-triazin-7-one Derivatives as the Acetylcholinesterase Inhibitors
Jin_2020_Oncol.Lett_19_1593Inhibition of acetylcholinesterase activity and beta-amyloid oligomer formation by 6-bromotryptamine A, a multi-target anti-Alzheimer's molecule
Jin_2020_Pest.Manag.Sci_76_227Detoxification enzymes associated with butene-fipronil resistance in Epacromius coerulipes
Jing_2020_Nat.Methods_17_1139An optimized acetylcholine sensor for monitoring in vivo cholinergic activity
Jithavech_2020_Front.Pharmacol_11_577998In Vitro Hepatic Metabolism of Curcumin Diethyl Disuccinate by Liver S9 from Different Animal Species
Johnson_2020_Cell.Death.Dis_11_628DPP8/9 inhibitors activate the CARD8 inflammasome in resting lymphocytes
Johnson_2020_Rejuvenation.Res_23_107Lipid Hydrolase Enzymes: Pragmatic Prolongevity Targets for Improved Human Healthspan?
Jokura_2020_J.Exp.Biol__An alpha7-related nicotinic acetylcholine receptor mediates the ciliary arrest response in pharyngeal gill slits of Ciona
Jonczyk_2020_Molecules_25_Dual Action of Dipyridothiazine and Quinobenzothiazine Derivatives-Anticancer and Cholinesterase-Inhibiting Activity
Jones_2020_PLoS.One_15_e0235341Larger active site in an ancestral hydroxynitrile lyase increases catalytically promiscuous esterase activity
Jonker_2020_J.Cell.Sci_133_Accurate measurement of fast endocytic recycling kinetics in real time
Jonnalagadda_2020_J.Phys.Chem.B_124_487Amyloid Peptide Scaffolds Coordinate with Alzheimer's Disease Drugs
Joshi_2020_Neuropharmacol__108118Opportunities for multiscale computational modelling of serotonergic drug effects in Alzheimer's disease
Josse_2020_Exp.Dermatol_29_168High bacterial colonization and lipase activity in microcomedones
Joubert_2020_Bioorg.Med.Chem.Lett__127075Discovery of 9-phenylacridinediones as highly selective butyrylcholinesterase inhibitors through structure-based virtual screening
Jouni_2020_Chemosphere_262_127724Elucidating pesticide sensitivity of two endogeic earthworm species through the interplay between esterases and glutathione S-transferases
Ju_2020_ACS.Chem.Neurosci_11_3346An Isoquinolinium Dual Inhibitor of Cholinesterases and Amyloid beta Aggregation Mitigates Neuropathological Changes in a Triple-Transgenic Mouse Model of Alzheimer's Disease
Juarez-Gomez_2020_Food.Chem_332_127409Novel electrochemical method to evaluate the antioxidant capacity of infusions and beverages, based on in situ formation of free superoxide radicals
Jun_2020_Anticancer.Res_40_2601ABHD12 Knockdown Suppresses Breast Cancer Cell Proliferation, Migration and Invasion
Jurischka_2020_Microb.Cell.Fact_19_11A secretion biosensor for monitoring Sec-dependent protein export in Corynebacterium glutamicum
Jusril_2020_Molecules_25_Combining In Silico and In Vitro Studies to Evaluate the Acetylcholinesterase Inhibitory Profile of Different Accessions and the Biomarker Triterpenes of Centella asiatica
Ka_2020_Molecules_25_Biosynthesis and Biological Activities of Newly Discovered Amaryllidaceae Alkaloids
Ka_2020_Phytochemistry_175_112390Gigantelline, gigantellinine and gigancrinine, cherylline- and crinine-type alkaloids isolated from Crinum jagus with anti-acetylcholinesterase activity
Kabeiseman_2020_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_243-244_110433Characterization of a monoacylglycerol lipase in the medicinal leech, Hirudo verbana
Kaewmaroeng_2020_Pak.J.Biol.Sci_23_904Simple Colorimetric Method for Cholinesterase-inhibitor Screening in Gastric Content by Using Phytoesterase Enzyme from Kidney Bean
Kakinuma_2020_eNeurologicalSci_19_100241Logopenic aphasia due to Lewy body disease dramatically improved with donepezil
Kalasz_2020_Molecules_25_Pharmacokinetics of Two Chlorine-Substituted Bis-Pyridinium Mono-Aldoximes with Regenerating Effect on Butyrylcholinesterase
Kalayci_2020_Arch.Pharm.(Weinheim)__e2000282Novel benzoic acid derivatives: Synthesis and biological evaluation as multitarget acetylcholinesterase and carbonic anhydrase inhibitors
Kalin_2020_Drug.Dev.Res_81_232Synthesis, molecular modeling studies, ADME prediction of arachidonic acid carbamate derivatives, and evaluation of their acetylcholinesterase activity
Kalji_2020_J.Colloid.Interface.Sci_567_285Colloidal graphene oxide enhances the activity of a lipase and protects it from oxidative damage: Insights from physicochemical and molecular dynamics investigations
Kandeil_2020_Environ.Sci.Pollut.Res.Int_27_19169Moringa seed extract alleviates titanium oxide nanoparticles (TiO2-NPs)-induced cerebral oxidative damage, and increases cerebral mitochondrial viability
Kanhed_2020_J.Biomol.Struct.Dyn__1Indoloquinoxaline derivatives as promising multi-functional anti-Alzheimer agents
Kapron_2020_J.Enzyme.Inhib.Med.Chem_35_9931,2,4-Triazole-based anticonvulsant agents with additional ROS scavenging activity are effective in a model of pharmacoresistant epilepsy
Karaduman_2020_Neurobiol.Aging_98_21The optomotor response of aging zebrafish reveals a complex relationship between visual motion characteristics and cholinergic system
Karakaya_2020_Nat.Prod.Res__1Evaluation of anticholinesterase effect of some Epilobium species and quantification of hyperoside by HPLC
Karakaya_2020_Saudi.Pharm.J_28_1Identification of non-alkaloid natural compounds of Angelica purpurascens (Ave-Lall.) Gilli. (Apiaceae) with cholinesterase and carbonic anhydrase inhibition potential
Karasova_2020_Iran.J.Pharm.Res_19_95Donepezil and Rivastigmine: Pharmacokinetic Profile and Brain-targeting After Intramuscular Administration in Rats
Karczewska-Kupczewska_2020_Endocr.Connect_9_90Changes in adipose tissue lipolysis gene expression and insulin sensitivity after weight loss
Kareti_2020_Curr.Ther.Res.Clin.Exp_93_100615In Silico Molecular Docking Analysis of Potential Anti-Alzheimer's Compounds Present in Chloroform Extract of Carissa carandas Leaf Using Gas Chromatography MS/MS
Karim_2020_Med.Chem_16_1007An Increasing Role of Polyphenols as Novel Therapeutics for Alzheimer's: A Review
Karimi_2020_BMC.Chem_14_64Design and synthesis of multi-target directed 1,2,3-triazole-dimethylaminoacryloyl-chromenone derivatives with potential use in Alzheimer's disease
Kariyanna_2020_Front.Physiol_11_594845Genome Mining and Expression Analysis of Carboxylesterase and Glutathione S-Transferase Genes Involved in Insecticide Resistance in Eggplant Shoot and Fruit Borer, Leucinodes orbonalis (Lepidoptera: Crambidae)
Karmouch_2020_Front.Mol.Neurosci_13_568171AChR beta-Subunit mRNAs Are Stabilized by HuR in a Mouse Model of Congenital Myasthenic Syndrome With Acetylcholinesterase Deficiency
Karthi_2020_Environ.Sci.Pollut.Res.Int__Biological effects of Avicennia marina (Forssk.) vierh. extracts on physiological, biochemical, and antimicrobial activities against three challenging mosquito vectors and microbial pathogens
Karthi_2020_J.Fungi.(Basel)_6_Target Activity of Isaria tenuipes (Hypocreales: Clavicipitaceae) Fungal Strains against Dengue Vector Aedes aegypti (Linn.) and Its Non-Target Activity Against Aquatic Predators
Kashyap_2020_Am.J.Clin.Exp.Urol_8_163Constitutively active HCN channels constrain detrusor excitability and modulate evoked contractions of human bladder
Kashyap_2020_Molecules_25_Ajmalicine and Reserpine: Indole Alkaloids as Multi-Target Directed Ligands Towards Factors Implicated in Alzheimer's Disease
Kashyap_2020_Neurosci.Insights_15_2633105520937693Scopoletin: Antiamyloidogenic, Anticholinesterase, and Neuroprotective Potential of a Natural Compound Present in Argyreia speciosa Roots by In Vitro and In Silico Study
Kasper_2020_World.J.Biol.Psychiatry__1Management of mild cognitive impairment (MCI): The need for national and international guidelines
Kasteel_2020_Arch.Toxicol_94_4055Acetylcholinesterase inhibition in electric eel and human donor blood: an in vitro approach to investigate interspecies differences and human variability in toxicodynamics
Kathman_2020_ACS.Chem.Biol_15_871Blockade of the Lysophosphatidylserine Lipase ABHD12 Potentiates Ferroptosis in Cancer Cells
Katic_2020_Chem.Biol.Interact__109287Effects of low-level imidacloprid oral exposure on cholinesterase activity, oxidative stress responses, and primary DNA damage in the blood and brain of male Wistar rats
Kato_2020_Biosci.Biotechnol.Biochem_84_1303Biosynthetic gene cluster identification and biological activity of lucilactaene from Fusarium sp. RK97-94
Katrucha_2020_Nat.Prod.Res__1Phenolic profile by HPLC-ESI-MS/MS and enzymatic inhibitory effect of Bryophyllum delagoense
Katz_2020_Neuropharmacol__108303The history of acetylcholinesterase inhibitors in the treatment of myasthenia gravis
Kaur_2020_Front.Microbiol_11_1568Salmonella Strain Specificity Determines Post-typhoid Central Nervous System Complications: Intervention by Lactiplantibacillus plantarum at Gut-Brain Axis
Kaur_2020_Int.J.Biol.Macromol__Structural and functional insights about unique extremophilic bacterial lipolytic enzyme from metagenome source
Kaur_2020_J.Basic.Clin.Physiol.Pharmacol__Allium cepa fraction attenuates STZ-induced dementia via cholinesterase inhibition and amelioration of oxidative stress in mice
Kaur_2020_Phys.Chem.Chem.Phys_22_15105Enzyme-based optical biosensors for organophosphate class of pesticide detection
Kaushal_2020_Ecotoxicol.Environ.Saf_207_111483A treatise on Organophosphate pesticide pollution: Current strategies and advancements in their environmental degradation and elimination
Kazakova_2020_Bioorg.Chem_101_104001Synthesis and cholinesterase inhibiting potential of A-ring azepano- and 3-amino-3,4-seco-triterpenoids
Ke_2020_Cancers.(Basel)_12_Genetic Analysis Reveals a Significant Contribution of CES1 to Prostate Cancer Progression in Taiwanese Men
Ke_2020_Evid.Based.Complement.Alternat.Med_2020_9818349Orlistat-Induced Gut Microbiota Modification in Obese Mice
Keita_2020_Parasit.Vectors_13_283Acetylcholinesterase (ace-1(R)) target site mutation G119S and resistance to carbamates in Anopheles gambiae (sensu lato) populations from Mali
Keller_2020_ACS.Infect.Dis_6_930Characterization of Serine Hydrolases Across Clinical Isolates of Commensal Skin Bacteria Staphylococcus epidermidis Using Activity-Based Protein Profiling
Keller_2020_Curr.Opin.Chem.Biol_54_45Activity-based protein profiling in bacteria: Applications for identification of therapeutic targets and characterization of microbial communities
Kellis_2020_Neurobiol.Stress_13_100279Cholinergic neurotransmission in the basolateral amygdala during cued fear extinction
Kent_2020_Neurotoxicol__Magnitude of Behavioral Deficits Varies with Job-Related Chlorpyrifos Exposure Levels among Egyptian Pesticide Workers
Kentrop_2020_Regul.Toxicol.Pharmacol_119_104823Pharmacokinetics and efficacy of atropine sulfate/obidoxime chloride co-formulation against VX in a guinea pig model
Keska_2020_Chem.Biol.Drug.Des_95_291Structure-activity relationships study on biological activity of peptides as dipeptidyl peptidase IV inhibitors by chemometric modeling
Khalaf_2020_Curr.Comput.Aided.Drug.Des_16_295DPP-IV Inhibitory Phenanthridines: Ligand, Structure-Based Design and Synthesis
Khalaf_2020_Curr.Comput.Aided.Drug.Des__Phenanthridine Sulfonamide Derivatives as Potential DPP-IV Inhibitors: Design, Synthesis and Biological Evaluation
Khalaf_2020_Pharmacol.Biochem.Behav__172956Clopidogrel combats neuroinflammation and enhances learning behavior and memory in a rat model of Alzheimer's disease
Khalifa_2020_Neurotox.Res_37_275Telmisartan Protects Against Aluminum-Induced Alzheimer-like Pathological Changes in Rats
Khan_2020_Am.J.Crit.Care_29_e39Effect of Delirium on Physical Function in Noncardiac Thoracic Surgery Patients
Khan_2020_Ecotoxicol.Environ.Saf_206_111335Enzymes mediating resistance to chlorpyriphos in Aphis fabae (Homoptera: Aphididae)
Khan_2020_J.Inflamm.Res_13_1125Structural Modeling of Wild and Mutant Forms of Human Plasma Platelet Activating Factor-Acetyl Hydrolase Enzyme
Khan_2020_Molecules_25_Green Tea Seed Isolated Theasaponin E1 Ameliorates AD Promoting Neurotoxic Pathogenesis by Attenuating Abeta Peptide Levels in SweAPP N2a Cells
Khan_2020_Sci.Rep_10_13220Resistance to deltamethrin and fenitrothion in dubas bug, Ommatissus lybicus de Bergevin (Homoptera: Tropiduchidae) and possible biochemical mechanisms
Khare_2020_J.Biomol.Struct.Dyn__1Screening and identification of secondary metabolites in the bark of Bauhinia variegata to treat Alzheimer's disease by using molecular docking and molecular dynamics simulations
Kharel_2020_Cureus_12_e7174The Efficacy of Pralidoxime in the Treatment of Organophosphate Poisoning in Humans: A Systematic Review and Meta-analysis of Randomized Trials
Khatami_2020_Planta.Med_86_1118Isolation and Characterization of Acetylcholinesterase Inhibitors from Piper longum and Binding Mode Predictions
Khaw_2020_Arch.Pharm.(Weinheim)__e2000156Probing simple structural modification of alpha-mangostin on its cholinesterase inhibition and cytotoxicity
Khaw_2020_J.Enzyme.Inhib.Med.Chem_35_1433LC-QTOF-MS analysis of xanthone content in different parts of Garcinia mangostana and its influence on cholinesterase inhibition
Khelifi_2020_Biotechnol.Appl.Biochem_67_983The antioxidant 2,3-dichloro,5,8-dihydroxy,1,4-naphthoquinone inhibits acetyl-cholinesterase activity and amyloid beta(42) aggregation: A dual target therapeutic candidate compound for the treatment of Alzheimer's disease
Khelifi_2020_Cell.Mol.Biol.(Noisy-le-grand)_66_9Evaluation of in vitro biological activities: antioxidant; anti-inflammatory; anti-cholinesterase; anti- xanthine oxidase, anti-superoxyde dismutase, anti-alpha-glucosidase and cytotoxic of 19 bioflavonoids
Kho_2020_Clin.Toxicol.(Phila)__1Long term use of donepezil and QTc prolongation
Khoma_2020_Bull.Environ.Contam.Toxicol__Biochemical Responses of the Bivalve Mollusk Unio tumidus Inhabiting a Small Power Plant Reservoir on the Dniester River Basin, Ukraine
Khosla_2020_Plant.Cell_32_2639Structure-Function Analysis of SMAX1 Reveals Domains That Mediate Its Karrikin-Induced Proteolysis and Interaction with the Receptor KAI2
Kielczewska_2020_J.Steroid.Biochem.Mol.Biol__105776The synthesis and cholinesterase inhibitory activities of solasodine analogues with seven-membered F ring
Kilianova_2020_Can.J.Physiol.Pharmacol__Expression of cholinesterases and their anchoring proteins in rat heart
Kim_2020_Antioxidants.(Basel)_9_Anti-Amnesic Effect of Walnut via the Regulation of BBB Function and Neuro-Inflammation in Abeta(1-42)-Induced Mice
Kim_2020_Biomolecules_10_Structural and Biophysical Analyses of Human N-Myc Downstream-Regulated Gene 3 (NDRG3) Protein
Kim_2020_Biomolecules_10_E180Inhibitory Activity of Flavonoids, Chrysoeriol and Luteolin-7-O-Glucopyranoside, on Soluble Epoxide Hydrolase from Capsicum chinense
Kim_2020_Fish.Shellfish.Immunol_97_194Effects on hematological parameters, antioxidant and immune responses, AChE, and stress indicators of olive flounders, Paralichthys olivaceus, raised in bio-floc and seawater challenged by Edwardsiella tarda
Kim_2020_Fish.Shellfish.Immunol_97_581Toxic effects of waterborne nitrite exposure on antioxidant responses, acetylcholinesterase inhibition, and immune responses in olive flounders, Paralichthys olivaceus, reared in bio-floc and seawater
Kim_2020_Food.Sci.Biotechnol_29_1295Antibacterial and in vitro antidementia effects of aronia (Aronia melanocarpa) leaf extracts
Kim_2020_J.Am.Med.Dir.Assoc_21_707Authors' Response to Association between Acetylcholinesterase Inhibitors and Osteoporotic Fractures in Older Persons With Alzheimer's Disease
Kim_2020_J.Clin.Med_9_Comparison of the Effects of Sugammadex, Neostigmine, and Pyridostigmine on Postoperative Nausea and Vomiting: A Propensity Matched Study of Five Hospitals
Kim_2020_J.Ethnopharmacol__112843Casticin ameliorates scopolamine-induced cognitive dysfunction in mice
Kim_2020_J.Food.Biochem__e13162Memory-enhancing effects of Ishige foliacea extract: In vitro and in vivo study
Kim_2020_J.Lipid.Res__The grease trap: Uncovering the mechanism of the hydrophobic lid in Cutibacterium acnes lipase
Kim_2020_J.Microbiol.Biotechnol_30_427Middle East Respiratory Syndrome-Coronavirus Infection into Established hDPP4-Transgenic Mice Accelerates Lung Damage Via Activation of the Pro-Inflammatory Response and Pulmonary Fibrosis
Kim_2020_Microb.Cell.Fact_19_97Functional expression of polyethylene terephthalate-degrading enzyme (PETase) in green microalgae
Kim_2020_Nutrients_12_Anti-Obesity Effect of DKB-117 through the Inhibition of Pancreatic Lipase and alpha-Amylase Activity
Kim_2020_PLoS.One_15_e0227820Effect of acetylcholinesterase inhibitors on post-stroke cognitive impairment and vascular dementia: A meta-analysis
Kimmel_2020_J.Am.Chem.Soc__Solid-Phase Synthesis of Megamolecules
Kioukis_2020_BMC.Genomics_21_48Intraspecific diversification of the crop wild relative Brassica cretica Lam. using demographic model selection
Kisa_2020_Bioorg.Chem_101_104066Bioactivity and molecular docking studies of some nickel complexes: New analogues for the treatment of Alzheimer, glaucoma and epileptic diseases
Kishimoto_2020_Sci.Rep_10_1299Heterologous expression of xanthophyll esterase genes affects carotenoid accumulation in petunia corollas
Kitadokoro_2020_Sci.Rep_10_5469Crystal structure of pathogenic Staphylococcus aureus lipase complex with the anti-obesity drug orlistat
Kladar_2020_Plant.Foods.Hum.Nutr__St. John's Wort Herbal Teas - Biological Potential and Chemometric Approach to Quality Control
Kladnik_2020_Int.J.Mol.Sci_21_Structural Isomerism and Enhanced Lipophilicity of Pyrithione Ligands of Organoruthenium(II) Complexes Increase Inhibition on AChE and BuChE
Klein-Junior_2020_J.Nat.Prod__Bioactive Azepine-Indole Alkaloids from Psychotria nemorosa
Kleine-Weber_2020_Emerg.Microbes.Infect_9_155Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus
Klincic_2020_Mar.Pollut.Bull_158_111413Persistent organic pollutants in tissues of farmed tuna from the Adriatic Sea
Klinge_2020_Neurogastroenterol.Motil__e13948Colonic motility in patients with type 1 diabetes and gastrointestinal symptoms
Klocker_2020_Cancers.(Basel)_12_Decreased Activity of Circulating Butyrylcholinesterase in Blood Is an Independent Prognostic Marker in Pancreatic Cancer Patients
Kmezik_2020_Biotechnol.Biofuels_13_60Multimodular fused acetyl-feruloyl esterases from soil and gut Bacteroidetes improve xylanase depolymerization of recalcitrant biomass
Knakker_2020_Behav.Brain.Res__112897Delay-dependent cholinergic modulation of visual short-term memory in rhesus macaques
Knatko_2020_iScience_23_101638Downregulation of Keap1 Confers Features of a Fasted Metabolic State
Knezevic_2020_Org.Biomol.Chem_18_9675Structural isomers of saligenin-based beta2-agonists: synthesis and insight into the reaction mechanism
Knorr_2020_Apoptosis_25_730Acetylcholinesterase promotes apoptosis in insect neurons
Knott_2020_Proc.Natl.Acad.Sci.U.S.A_117_25476Characterization and engineering of a two-enzyme system for plastics depolymerization
Kobrlova_2020_Toxicology__152541Effect of P-glycoprotein on the availability of oxime reactivators in the brain
Kobus-Cisowska_2020_J.Food.Sci_85_3003Chocolate desserts with ricotta hydrolysates: In vitro study of inhibitory activity against angiotensin-converting enzyme and cholinesterase
Kocakaya_2020_Iran.J.Pharm.Res_19_187Selective in-vitro Enzymes' Inhibitory Activities of Fingerprints Compounds of Salvia Species and Molecular Docking Simulations
Kocaturk_2020_Res.Vet.Sci_134_147Changes in choline and cholinesterase in saliva of dogs with parvovirus infection
Koch_2020_Angew.Chem.Int.Ed.Engl_59_13575Probing Selectivity and Creating Structural Diversity Through Hybrid Polyketide Synthases
Kocyigit_2020_Arch.Pharm.(Weinheim)__e2000202Synthesis, characterization, and biological studies of chalcone derivatives containing Schiff bases: Synthetic derivatives for the treatment of epilepsy and Alzheimer's disease
Kocyigit_2020_J.Biomol.Struct.Dyn__11,2,3-Triazole substituted phthalocyanine metal complexes as potential inhibitors for anticholinesterase and antidiabetic enzymes with molecular docking studies
Koenig_2020_Toxics_8_Development of a Larval Zebrafish Model for Acute Organophosphorus Nerve Agent and Pesticide Exposure and Therapeutic Evaluation
Kofman_2020_PLoS.One_15_e0239738Developmental and social deficits and enhanced sensitivity to prenatal chlorpyrifos in PON1-/- mouse pups and adults
Koh_2020_Mol.Genet.Genomic.Med_8_e1108VPS13D-related disorders presenting as a pure and complicated form of hereditary spastic paraplegia
Kohelova_2020_Bioorg.Chem_107_104567Alkaloids of Zephyranthes citrina (Amaryllidaceae) and their implication to Alzheimer's disease: Isolation, structural elucidation and biological activity
Kok_2020_Nat.Chem.Biol_16_997Discovery of small-molecule enzyme activators by activity-based protein profiling
Kokkonen_2020_Comput.Struct.Biotechnol.J_18_805The impact of tunnel mutations on enzymatic catalysis depends on the tunnel-substrate complementarity and the rate-limiting step
Kolanko_2020_J.Neurol_267_3268Using amyloid PET imaging to diagnose Alzheimer's disease in patients with multiple sclerosis
Konecny_2020_Biomolecules_11_Pursuing the Complexity of Alzheimer's Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N-Methyl-d-Aspartate Receptor Antagonists
Kong_2020_Molecules_25_The Cholinesterase Inhibitory Properties of Stephaniae Tetrandrae Radix
Koola_2020_Psychiatry.Res_291_113285Meta-analysis of randomized controlled trials of galantamine in schizophrenia: significant cognitive enhancement
Koola_2020_Psychiatry.Res_293_113409Galantamine-Memantine combination in the treatment of Alzheimer's disease and beyond
Kopjar_2020_Clin.Drug.Investig_40_775High Doses of Delta(9)-Tetrahydrocannabinol Might Impair Irinotecan Chemotherapy: A Review of Potentially Harmful Interactions
Kopke_2020_eNeuro_7_Carrier of Wingless (Cow) Regulation of Drosophila Neuromuscular Junction Development
Kopp_2020_Am.J.Med.Genet.A__e62025Pathogenic paternally inherited NLGN4X deletion in a female with autism spectrum disorder: Clinical, cytogenetic, and molecular characterization
Kori_2020_J.Biochem.Mol.Toxicol__e22477Identification of markers of depression and neurotoxicity in pesticide exposed agriculture workers
Korkmaz_2020_Turk.J.Chem_44_1110New sandwich-type polymeric potassium-dicyanoargentate(I) complex: synthesis, characterization and enzymatic activity
Kosak_2020_Eur.J.Med.Chem_197_112282N-alkylpiperidine carbamates as potential anti-Alzheimer's agents
Kosanic_2020_EXCLI.J_19_442Hygrophorus eburneus, edible mushroom, a promising natural bioactive agent
Kosanic_2020_Int.J.Med.Mushrooms_22_347The Health Promoting Effects of the Fruiting Bodies Extract of the Peppery Milk Cap Mushroom Lactarius piperatus (Agaricomycetes) from Serbia
Koseler_2020_In.Vivo_34_361Genome-wide DNA Methylation Profiling of Blood from Monozygotic Twins Discordant for Myocardial Infarction
Kosowska_2020_Int.J.Mol.Sci_21_Sitagliptin Modulates the Response of Ovarian Cancer Cells to Chemotherapeutic Agents
Kosters_2020_J.Chromatogr.A_1624_461258Fast sample preparation for organo(fluoro)phosphate quantification approaches in lithium ion battery electrolytes by means of gas chromatographic techniques
Koutova_2020_Molecules_25_Chemical and Biological Aspects of Montanine-Type Alkaloids Isolated from Plants of the Amaryllidaceae Family
Kouzu_2020_Gastric.Cancer_23_356Risk factors for nonalcoholic fatty liver disease after gastrectomy for gastric cancer
Kovarik_2020_Neuropharmacol__108111Efficient detoxification of nerve agents by oxime-assisted reactivation of acetylcholinesterase mutants
Kovida_2020_Analyst__Rapid on-site and naked-eye detection of common nitro pesticides with ionic liquids
Kowalczyk_2020_Front.Neurosci_14_730Bergapten Improves Scopolamine-Induced Memory Impairment in Mice via Cholinergic and Antioxidative Mechanisms
Kranawetvogl_2020_Drug.Test.Anal__A novel HPLC-DAD method for the simultaneous quantification of the enzyme-reactivating oximes obidoxime, pralidoxime and HI-6 in human plasma
Kratky_2020_Curr.Top.Med.Chem_20_2094N-[3,5-Bis(trifluoromethyl)phenyl]-5-bromo-2-hydroxybenzamide Analogues: Novel Acetyl- and Butyrylcholinesterase Inhibitors
Kratky_2020_Curr.Top.Med.Chem_20_2106Novel Iodinated Hydrazide-hydrazones and their Analogues as Acetyl- and Butyrylcholinesterase Inhibitors
Kratky_2020_Molecules_25_N-Alkyl-2-[4-(trifluoromethyl)benzoyl]hydrazine-1-carboxamides and Their Analogues: Synthesis and Multitarget Biological Activity
Krishnaswamy_2020_Life.Sci__118545Effect of short-term oral supplementation of crocin on age-related oxidative stress, cholinergic, and mitochondrial dysfunction in rat cerebral cortex
Kristensen_2020_J.Lipid.Res__ANGPTL4 inactivates lipoprotein lipase by catalyzing the irreversible unfolding of LPL's hydrolase domain
Kristensen_2020_Proc.Natl.Acad.Sci.U.S.A__Unfolding of monomeric lipoprotein lipase by ANGPTL4: Insight into the regulation of plasma triglyceride metabolism
Krizkovska_2020_Pharmaceuticals.(Basel)_14_Comparison of Chemical Composition and Biological Activities of Eight Selaginella Species
Krska_2020_Biotechnol.Biofuels_13_68Investigation of a thermostable multi-domain xylanase-glucuronoyl esterase enzyme from Caldicellulosiruptor kristjanssonii incorporating multiple carbohydrate-binding modules
Kryukova_2020_Biochemistry.(Mosc)_85_709Effect of Cysteine Residue Substitution in the GCSAG Motif of the PMGL2 Esterase Active Site on the Enzyme Properties
Krzyzowski_2020_Insects_11_The Effect of Rosmarinus officinalis Essential Oil Fumigation on Biochemical, Behavioral, and Physiological Parameters of Callosobruchus maculatus
Kuang_2020_J.Agric.Food.Chem_68_8362Preparation of Lipase-Electrospun SiO(2) Nanofiber Membrane Bioreactors and Their Targeted Catalytic Ability at the Macroscopic Oil-Water Interface
Kubo_2020_BMC.Nephrol_21_402Protective effects of DPP-4 inhibitor on podocyte injury in glomerular diseases
Kucinski_2020_Psychopharmacology.(Berl)_237_137Rescuing the attentional performance of rats with cholinergic losses by the M1 positive allosteric modulator TAK-071
Kucukdogru_2020_Metab.Brain.Dis__Neuroprotective effects of boron nitride nanoparticles in the experimental Parkinson's disease model against MPP+ induced apoptosis
Kudavidanage_2020_Biology.(Basel)_9_Commercial Formulation of Chlorpyrifos Alters Neurological Behaviors and Fertility
Kulminskaya_2020_Biochimie_169_62Protein-protein interactions regulate the activity of Adipose Triglyceride Lipase in intracellular lipolysis
Kumar_2020_3.Biotech_10_509Synthesis of novel 4-methylthiocoumarin and comparison with conventional coumarin derivative as a multi-target-directed ligand in Alzheimer's disease
Kumar_2020_Chirality_32_1377Candida antarctica lipase-B-catalyzed kinetic resolution of 1,3-dialkyl-3-hydroxymethyl oxindoles
Kumar_2020_Comput.Biol.Chem_88_107355In silico modeling for dual inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) enzymes in Alzheimer's disease
Kumar_2020_Curr.Comput.Aided.Drug.Des__Molecular dynamics assisted mechanistic insight of Val430-Ala mutation of Rv1592c protein in isoniazid resistant Mycobacterium tuberculosis
Kumar_2020_Curr.Top.Med.Chem_20_1601A Multi-layered Variable Selection Strategy for QSAR Modeling of Butyrylcholinesterase Inhibitors
Kumar_2020_Front.Bioeng.Biotechnol_8_642A Broad Temperature Active Lipase Purified From a Psychrotrophic Bacterium of Sikkim Himalaya With Potential Application in Detergent Formulation
Kumar_2020_Int.J.Microbiol_2020_8894215Aspergillus nidulans: A Potential Resource of the Production of the Native and Heterologous Enzymes for Industrial Applications
Kumar_2020_J.Biochem.Mol.Toxicol__e22677Occupational exposure to pesticides in female tea garden workers and adverse birth outcomes
Kumar_2020_J.Biomol.Struct.Dyn__1Drug repurposing for Alzheimer's disease: in silico and in vitro investigation of FDA-approved drugs as acetylcholinesterase inhibitors
Kumar_2020_Neurotoxicol__Memory improvement by modafinil at cost of metabolic hazards? A study to decipher the benefits and risks of modafinil in rats
Kumari_2020_Brain.Res.Bull__Tacrine accelerates spatial long-term memory via improving impaired neural oscillations and modulating GAD isomers including neuro-receptors in the hippocampus of APP/PS1 AD mice
Kundrick_2020_Ann.N.Y.Acad.Sci__Delayed midazolam dose effects against soman in male and female plasma carboxylesterase knockout mice
Kundu_2020_J.Biomol.Struct.Dyn__1Interaction of selected biomolecules and metabolites with amyloidogenic proteins
Kurahashi_2020_Enzyme.Microb.Technol_140_109626Highly active enzymes produced by directed evolution with stability-based selection
Kurnutala_2020_Cureus_12_e10721Pseudocholinesterase Deficiency - Is Succinylcholine Still Needed to Facilitate Endotracheal Intubation?
Kuthiroly_2020_Indian.J.Pediatr__Lipoprotein Lipase Deficiency
Kwon_2020_Acta.Pharm.Sin.B_10_42Cytochrome P450 endoplasmic reticulum-associated degradation (ERAD): therapeutic and pathophysiological implications
Kyle_2020_Parkinsonism.Relat.Disord_75_55Treatment of psychosis in Parkinson's disease and dementia with Lewy Bodies: A review
Labanca_2020_Antioxidants.(Basel)_9_New Insights into the Exploitation of Vitis vinifera L. cv. Aglianico Leaf Extracts for Nutraceutical Purposes
Lachowicz_2020_Antioxidants.(Basel)_9_Improvement of Health-Promoting Functionality of Rye Bread by Fortification with Free and Microencapsulated Powders from Amelanchier alnifolia Nutt
Lackie_2020_J.Neurochem_153_727Modulation of hippocampal neuronal resilience during aging by the Hsp70/Hsp90 co-chaperone STI1
Laetz_2020_Aquat.Toxicol_221_105424Sublethal neurotoxicity of organophosphate insecticides to juvenile coho salmon
Laforgia_2020_Genes.(Basel)_11_The First Case of Congenital Myasthenic Syndrome Caused by a Large Homozygous Deletion in the C-Terminal Region of COLQ (Collagen Like Tail Subunit of Asymmetric Acetylcholinesterase) Protein
Lagardere_2020_Sci.Rep_10_19954FluoSim: simulator of single molecule dynamics for fluorescence live-cell and super-resolution imaging of membrane proteins
Lai_2020_Front.Aging.Neurosci_12_121The Comparative Efficacy of Multiple Interventions for Mild Cognitive Impairment in Alzheimer's Disease: A Bayesian Network Meta-Analysis
Laino_2020_Pestic.Biochem.Physiol_165_104559Study of the effect of cypermethrin on the spider Polybetes phytagoricus in different energy states
Laizure_2020_Xenobiotica_50_245Inhibition of Carboxylesterase-1 Alters Clopidogrel Metabolism and Disposition
Laizure_2020_Xenobiotica_50_92Is Genetic Variability in Carboxylesterase-1 and Carboxylesterase-2 Drug Metabolism an Important Component of Personalized Medicine?
Laliberte_2020_Front.Neural.Circuits_14_38Mesoscopic Mapping of Stimulus-Selective Response Plasticity in the Visual Pathways Modulated by the Cholinergic System
Lalut_2020_Sci.Rep_10_3014Rational design of novel benzisoxazole derivatives with acetylcholinesterase inhibitory and serotoninergic 5-HT4 receptors activities for the treatment of Alzheimer's disease
Lam_2020_Biomed.Pharmacother_130_110624Melaleuca alternifolia (tea tree) oil and its monoterpene constituents in treating protozoan and helminthic infections
Lam_2020_Curr.Anesthesiol.Rep__1The Multiple Casualty Scenario: Role of the Anesthesiologist
Lammari_2020_Int.J.Pharm__120138Nanocapsules Containing Saussurea lappa Essential Oil: Formulation, Characterization, Antidiabetic, Anti-Cholinesterase and Anti-Inflammatory Potentials
Lampela_2020_J.Alzheimers.Dis__Asthma and Chronic Obstructive Pulmonary Disease as a Comorbidity and Association with the Choice of Antidementia Medication Among Persons with Alzheimer's Disease
Landis_2020_Integr.Environ.Assess.Manag_16_28Integration of Chlorpyrifos Acetylcholinesterase Inhibition, Water Temperature, and Dissolved Oxygen Concentration into a Regional Scale Multiple Stressor Risk Assessment Estimating Risk to Chinook Salmon
Landry_2020_Sci.Total.Environ_726_138515Biological markers to establish a relationship between the health status of the St. Lawrence River yellow perch (Perca flavescens) with a gradient of anthropogenic disturbances
Lane_2020_J.Pharmacol.Exp.Ther_375_115Oral Pretreatment with Galantamine Effectively Mitigates the Acute Toxicity of a Supralethal Dose of Soman in Cynomolgus Monkeys Posttreated with Conventional Antidotes
Lange_2020_Protein.Sci_29_330Facilities that make the PDB data collection more powerful
Lapin_2020_Annu.Rev.Phytopathol__Origins and Immunity Networking Functions of EDS1 Family Proteins
Larrazabal-Fuentes_2020_Front.Pharmacol_11_594174Chemical Profiling, Antioxidant, Anticholinesterase, and Antiprotozoal Potentials of Artemisia copa Phil. (Asteraceae)
Larrimore_2020_Prog.Neuropsychopharmacol.Biol.Psychiatry__109961A plant-derived cocaine hydrolase prevents cocaine overdose lethality and attenuates cocaine-induced drug seeking behavior
Laszlo_2020_Nat.Commun_11_4363ABHD4-dependent developmental anoikis safeguards the embryonic brain
Lauria_2020_Nat.Cell.Biol_22_1239SMN-primed ribosomes modulate the translation of transcripts related to spinal muscular atrophy
Lazewska_2020_Eur.J.Med.Chem_207_112743Rational design of new multitarget histamine H(3) receptor ligands as potential candidates for treatment of Alzheimer's disease
Le-Nhat-Thuy_2020_Bioorg.Med.Chem.Lett_30_127404Synthesis and biological evaluation of novel quinazoline-triazole hybrid compounds with potential use in Alzheimer's disease
Le_2020_Biotechnol.Lett__A novel huperzine A-producing endophytic fungus Fusarium sp. Rsp5.2 isolated from Huperzia serrate
Le_2020_Elife_9_Modular metabolite assembly in C. elegans depends on carboxylesterases and formation of lysosome-related organelles
Leal_2020_Toxins.(Basel)_12_The Insecticidal Activity of Rhinella schneideri (Werner, 1894) Paratoid Secretion in Nauphoeta cinerea Cocroaches
Ledesma_2020_Addict.Biol__e12883Adolescent binge-ethanol accelerates cognitive impairment and beta-amyloid production and dysregulates endocannabinoid signaling in the hippocampus of APP/PSE mice
Lee_2020_Anal.Chem_92_16051Selective Butyrate Esterase Probe for the Rapid Colorimetric and Fluorogenic Identification of Moraxella catarrhalis
Lee_2020_Angew.Chem.Int.Ed.Engl_59_2349Flexible Total Synthesis of 11-Deoxylandomycins and Their Non-Natural Analogues by Way of Asymmetric Metal Catalysis
Lee_2020_Bioorg.Med.Chem_28_115735Preparation and evaluation of soluble epoxide hydrolase inhibitors with improved physical properties and potencies for treating diabetic neuropathic pain
Lee_2020_Chem.Sci_12_1090Lipase mimetic cyclodextrins
Lee_2020_Front.Cell.Neurosci_14_281Synaptic Organizers in Alzheimer's Disease: A Classification Based on Amyloid-beta Sensitivity
Lee_2020_J.Am.Geriatr.Soc_68_129Summative Effects of Vascular Risk Factors on the Progression of Alzheimer Disease
Lee_2020_J.Biol.Chem_295_4181Flexibility of the petunia strigolactone receptor DAD2 promotes its interaction with signaling partners
Lee_2020_Molecules_25_1938Simultaneous Analysis of Fenthion and Its Five Metabolites in Produce Using Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry
Lee_2020_Molecules_25_4945Phytochemical Composition, Antioxidant Capacity, and Enzyme Inhibitory Activity in Callus, Somaclonal Variant, and Normal Green Shoot Tissues of Catharanthus roseus (L) G. Don
Lee_2020_Pestic.Biochem.Physiol_164_33Regional and seasonal detection of resistance mutation frequencies in field populations of Anopheles Hyrcanus Group and Culex pipiens complex in Korea
Leembruggen_2020_Autism.Res_13_691Colonic dilation and altered ex vivo gastrointestinal motility in the neuroligin-3 knockout mouse
Lefevre_2020_Neurotrauma.Rep_1_125Enteric Nervous System Remodeling in a Rat Model of Spinal Cord Injury: A Pilot Study
Lei_2020_Front.Bioeng.Biotechnol_8_950Pickering Emulsion-Based Microreactors for Size-Selective Interfacial Enzymatic Catalysis
Leite_2020_Eur.Biophys.J_49_435Low-resolution molecular shape, biochemical characterization and emulsification properties of a halotolerant esterase from Bacillus licheniformis
Lekvongphiboon_2020_Environ.Geochem.Health__Combined toxicity of imidacloprid and cadmium on histopathology and acetylcholinesterase activity in aquatic oligochaetes (Tubifex tubifex Muller, 1774)
Lenina_2020_Sci.Rep_10_16611Slow-binding reversible inhibitor of acetylcholinesterase with long-lasting action for prophylaxis of organophosphate poisoning
Leon-Salas_2020_Arch.Gerontol.Geriatr_90_104171Pharmacologic interventions for prevention of delirium in hospitalized older people: A meta-analysis
Leonard_2020_Food.Chem_346_128606Extrusion improves the phenolic profile and biological activities of hempseed (Cannabis sativa L.) hull
Leonel_2020_Environ.Res__110210Analysis of PON1 gene polymorphisms (rs662 and rs854560) and inflammatory markers in organophosphate pesticides exposed cohorts from two distinct populations
Leonel_2020_Front.Public.Health_8_534902Mixture of Organophosphates Chronic Exposure and Pancreatic Dysregulations in Two Different Population Samples
Leporini_2020_Plants.(Basel)_9_The Essential Oil of Salvia rosmarinus Spenn. from Italy as a Source of Health-Promoting Compounds: Chemical Profile and Antioxidant and Cholinesterase Inhibitory Activity
Letellier_2020_Elife_9_Optogenetic control of excitatory post-synaptic differentiation through neuroligin-1 tyrosine phosphorylation
Lew_2020_Mini.Rev.Med.Chem__Discovering the Potentials of Medicinal Mushrooms in Combating Depression - A Review
Li_2020_ACS.Appl.Mater.Interfaces_12_2581Promoting Active Sites in MOF-Derived Homobimetallic Hollow Nanocages as a High-Performance Multifunctional Nanozyme Catalyst for Biosensing and Organic Pollutant Degradation
Li_2020_ACS.Chem.Biol_15_226Genomics-Driven Discovery of Phytotoxic Cytochalasans Involved in the Virulence of the Wheat Pathogen Parastagonospora nodorum
Li_2020_AMB.Express_10_33A safety type of genetically engineered bacterium that degrades chemical pesticides
Li_2020_Acta.Pharm.Sin.B_10_646Discovery of nitazoxanide-based derivatives as autophagy activators for the treatment of Alzheimer's disease
Li_2020_Aging.Clin.Exp.Res__Admission serum cholinesterase concentration for prediction of in-hospital mortality in very elderly patients with acute ischemic stroke: a retrospective study
Li_2020_Anal.Bioanal.Chem_412_5583A dual-mode nanoprobe for the determination of parathion methyl based on graphene quantum dots modified silver nanoparticles
Li_2020_Anal.Chem_92_11654Development of a Highly Sensitive Enzyme-Linked Immunosorbent Assay for Mouse Soluble Epoxide Hydrolase Detection by Combining a Polyclonal Capture Antibody with a Nanobody Tracer
Li_2020_Anal.Chem_92_3198Design of Red Emissive Carbon Dots: Robust Performance for Analytical Applications in Pesticide Monitoring
Li_2020_Anal.Chem_92_3361Colorimetric Differentiation of Flavonoids Based on Effective Reactivation of Acetylcholinesterase Induced by Different Affnities between Flavonoids and Metal Ions
Li_2020_Anal.Chem_92_7334Development of Improved Double Nanobody Sandwich ELISAs for Human Soluble Epoxide Hydrolase Detection in PBMCs of Diabetic and Pre-frontal Cortex of Multiple Sclerosis Patients
Li_2020_Analyst_145_5206Ultrasensitive detection of butyrylcholinesterase activity based on the inner filter effect of MnO(2) nanosheets on sulfur nanodots
Li_2020_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids__158873Isolated Plin5-deficient cardiomyocytes store less lipid droplets than normal, but without increased sensitivity to hypoxia
Li_2020_Bioorg.Chem_107_104583Efficient synthesis of cyano-containing multi-substituted indoles catalyzed by lipase
Li_2020_Biosens.Bioelectron_169_112605MnO(2) switch-bridged DNA walker for ultrasensitive sensing of cholinesterase activity and organophosphorus pesticides
Li_2020_Cell.Mol.Life.Sci_77_2461Astrocyte-specific NDRG2 gene: functions in the brain and neurological diseases
Li_2020_Colloids.Surf.B.Biointerfaces_188_110812Immobilized lipase in bio-based metal-organic frameworks constructed by biomimetic mineralization: A sustainable biocatalyst for biodiesel synthesis
Li_2020_Curr.Opin.Insect.Sci_41_106Fates of dietary sterols in the insect alimentary canal
Li_2020_Cytotech__Silencing of soluble epoxide hydrolase 2 gene reduces H2O2-induced oxidative damage in rat intestinal epithelial IEC-6 cells via activating PI3K/Akt/GSK3beta signaling pathway
Li_2020_Ecotoxicol.Environ.Saf_196_110548Positive correlation between human exposure to organophosphate esters and gastrointestinal cancer in patients from Wuhan, China
Li_2020_Ecotoxicol.Environ.Saf_199_110751Antioxidative enzyme activities in the Rhodeinae sinensis Gunther and Macrobrachium nipponense and multi-endpoint assessment under tonalide exposure
Li_2020_Environ.Sci.Pollut.Res.Int__Evaluation of toxicological responses and promising biomarkers of topmouth gudgeon (Pseudorasbora parva) exposed to fipronil at environmentally relevant levels
Li_2020_Environ.Sci.Technol_54_12130Organophosphate Diesters (Di-OPEs) Play a Critical Role in Understanding Global Organophosphate Esters (OPEs) in Fishmeal
Li_2020_Eur.J.Med.Chem_185_111862Reasonably activating Nrf2: A long-term, effective and controllable strategy for neurodegenerative diseases
Li_2020_Exp.Eye.Res__108003Inhibition of acetylcholinesterase attenuated retinal inflammation via suppressing NF-kappaB activation
Li_2020_Fitoterapia__104557New sesquiterpenoids bearing 11-methyl ester group of agarwood
Li_2020_Food.Chem_333_127452Characterization and crystal structure of prolyl endopeptidase from abalone (Haliotis discus hannai)
Li_2020_Food.Chem__128653Investigation of the transformation and toxicity of trichlorfon at the molecular level during enzymic hydrolysis of apple juice
Li_2020_Front.Bioeng.Biotechnol_8_694Functional Validation of Two Fungal Subfamilies in Carbohydrate Esterase Family 1 by Biochemical Characterization of Esterases From Uncharacterized Branches
Li_2020_Front.Endocrinol.(Lausanne)_11_567545Electrical Neurostimulation Promotes Brown Adipose Tissue Thermogenesis
Li_2020_Front.Microbiol_11_9Study on a Novel Cold-Active and Halotolerant Monoacylglycerol Lipase Widespread in Marine Bacteria Reveals a New Group of Bacterial Monoacylglycerol Lipases Containing Unusual C(A/S)HSMG Catalytic Motifs
Li_2020_Front.Neurol_11_939Myasthenia Gravis Coexisting With Primary Sjogren's Syndrome: Report of Three Cases and Literature Review
Li_2020_Int.J.Biol.Macromol_156_225Greatly enhancing the enantioselectivity of PvEH2, a Phaseolus vulgaris epoxide hydrolase, towards racemic 1,2-epoxyhexane via replacing its partial cap-loop
Li_2020_Iran.J.Basic.Med.Sci_23_600Nos2 deficiency enhances carbon tetrachloride-induced liver injury in aged mice
Li_2020_J.Agric.Food.Chem_68_3390Functional Characterization of two Carboxylesterase Genes Involved in Pyrethroid Detoxification in Helicoverpa armigera
Li_2020_J.Agric.Food.Chem_68_7609Chiral organophosphorous pesticides fosthiazate: absolute configuration, stereoselective bioactivity, toxicity, and degradation in vegetables
Li_2020_J.Agric.Food.Chem_68_7955New Flavoalkaloids with Potent alpha-Glucosidase and Acetylcholinesterase Inhibitory Activities from Yunnan Black Tea 'Jin-Ya'
Li_2020_J.Chem.Inf.Model_60_5255Protein Surface Printer for Exploring Protein Domains
Li_2020_J.Environ.Sci.Health.B__1miR-96-5p attenuates malathion-induced apoptosis of human kidney cells by targeting the ER stress marker DDIT3
Li_2020_J.Ethnopharmacol__113721Comparison of the Chemical Constituents of Raw Fructus Aurantii and Fructus Aurantii Stir-baked with Bran, and the Biological Effects of Auraptene
Li_2020_J.Hazard.Mater_407_124612Identification of key residues of carboxylesterase PxEst-6 involved in pyrethroid metabolism in Plutella xylostella (L.)
Li_2020_J.Med.Food_23_920Curcumin Alleviates the Side Effects of Cisplatin on Gastric Emptying of Mice by Inhibiting the Signal Changes of Acetylcholine and Interstitial Cells of Cajal
Li_2020_J.Med.chem_63_10030Discovery and Biological Evaluation of a Novel Highly Potent Selective Butyrylcholinsterase Inhibitor
Li_2020_J.Physiol.Sci_70_11Intracerebroventricular infusion of donepezil prevents cardiac remodeling and improves the prognosis of chronic heart failure rats
Li_2020_J.Sep.Sci_43_3793Application of accelerated solvent extraction coupled with online two-dimensional countercurrent chromatography for continuous extraction and separation of bioactive compounds from Citrus limon peel
Li_2020_J.Toxicol.Environ.Health.A__1Neurotoxicity and physiological stress in brain of zebrafish chronically exposed to tributyltin
Li_2020_Lipids.Health.Dis_19_63Identification of a novel LPL nonsense variant and further insights into the complex etiology and expression of hypertriglyceridemia-induced acute pancreatitis
Li_2020_Macromol.Rapid.Commun_41_e2000417Lipase-Catalyzed Reactive Extrusion: Copolymerization of sigma-Caprolactone and -Pentadecalactone
Li_2020_Mar.Environ.Res_157_104866Inhibition to crucial enzymes in the lethal effects of the dinoflagellate Karenia mikimotoi on the rotifer Brachionus plicatilis
Li_2020_Methods.Enzymol_643_225Focused rational iterative site-specific mutagenesis (FRISM)
Li_2020_Methods.Mol.Biol_2099_161Development of a Mouse-Adapted MERS Coronavirus
Li_2020_Molecules_25_3967Coumarin and Moracin Derivatives from Mulberry Leaves (Morus alba L.) with Soluble Epoxide Hydrolase Inhibitory Activity
Li_2020_Molecules_25_4658A De Novo Designed Esterase with p-Nitrophenyl Acetate Hydrolysis Activity
Li_2020_Org.Lett__A Dual-Protein Cascade Reaction for the Regioselective Synthesis of Quinoxalines
Li_2020_PLoS.One_15_e0239497Comprehensive profiling of phytochemical compounds, antioxidant activities, anti-HepG2 cell proliferation, and cholinesterase inhibitory potential of Elaeagnus mollis leaf extracts
Li_2020_PLoS.One_15_e0239632An efficient LSPR method to quantitatively detect dimethoate: Development, characterization and evaluation
Li_2020_Pest.Manag.Sci_77_1936Reduced insecticide sensitivity of the wheat aphid Sitobion miscanthi after infection by the secondary bacterial symbiont Hamiltonella defensa
Li_2020_Pest.Manag.Sci_77_1945Widespread Multiple Insecticide Resistance in the Major Dengue Vector Aedes albopictus in Hainan Province, China
Li_2020_Pest.Manag.Sci_77_2097Functional analysis of a carboxylesterase gene involved in beta-cypermethrin and phoxim resistance in Plutella xylostella (L.)
Li_2020_Pestic.Biochem.Physiol_170_104701Inhibitory activities of flavonoids from Eupatorium adenophorum against acetylcholinesterase
Li_2020_Phytochemistry_183_112593Eupholides A-H, abietane diterpenoids from the roots of Euphorbia fischeriana, and their bioactivities
Li_2020_Protein.Expr.Purif__105804Efficient Improvement of Surface Displayed Lipase from Rhizomucor miehei in PichiaPink(TM) Protease-deficient System
Li_2020_Sci.Rep_10_16168GALNT2 regulates ANGPTL3 cleavage in cells and in vivo of mice
Li_2020_Sci.Total.Environ_720_137616Rapid biodegradation of polyphenylene sulfide plastic beads by Pseudomonas sp
Li_2020_iScience__101160The MERS-CoV receptor DPP4 as a candidate binding target of the SARS-CoV-2 spike
Liang_2020_Aquat.Toxicol__105621Effects of ammonia exposure on antioxidant function, immune response and NF-kappaB pathway in Chinese Strip-necked Turtle (Mauremys sinensis)
Liang_2020_Int.J.Biol.Macromol_161_525A novel feruloyl esterase with high rosmarinic acid hydrolysis activity from Bacillus pumilus W3
Liang_2020_J.Biol.Chem_295_1047Structural insights into the catalytic mechanism of lovastatin hydrolase
Liang_2020_J.Chromatogr.A__461003Immobilized angiotensin II type I receptor: A powerful method of high throughput screening for antihypertensive compound identification through binding interaction analysis
Liang_2020_J.Exp.Clin.Cancer.Res_39_176Cancer-derived exosomal TRIM59 regulates macrophage NLRP3 inflammasome activation to promote lung cancer progression
Liao_2020_Bioorg.Chem_99_103844Design, synthesis and biological evaluation of novel carboline-cinnamic acid hybrids as multifunctional agents for treatment of Alzheimer's disease
Liao_2020_Br.J.Pharmacol_177_4275Heterologous expression of concatenated nicotinic ACh receptors: Pros and cons of subunit concatenation and recommendations for construct designs
Liao_2020_J.Org.Chem_85_1298Increasing Structural Diversity of Natural Products by Michael Addition with ortho-Quinone Methide as the Acceptor
Liao_2020_Molecules_25_Walnut Oil Prevents Scopolamine-Induced Memory Dysfunction in a Mouse Model
Lillich_2020_Front.Pharmacol_11_554961Multi-Target Approaches in Metabolic Syndrome
Lim_2020_Int.J.Mol.Sci_21_8983Application of the RBBP9 Serine Hydrolase Inhibitor, ML114, Decouples Human Pluripotent Stem Cell Proliferation and Differentiation
Lim_2020_J.Chem.Theory.Comput_16_2778Fragment Pose Prediction Using Non-equilibrium Candidate Monte Carlo and Molecular Dynamics Simulations
Lim_2020_Vet.Clin.Pathol_49_607The 1,2-o-dilauryl-rac-glycero-3-glutaric acid-(6'-methylresorufin) ester (DGGR) lipase assay in cats and dogs is not specific for pancreatic lipase
Lima_2020_Bioorg.Chem_104_104215Geissoschizoline, a promising alkaloid for Alzheimer's disease: Inhibition of human cholinesterases, anti-inflammatory effects and molecular docking
Lima_2020_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1164_122493LC-HRMS and acetylcholinesterase affinity assay as a workflow for profiling alkaloids in Annona salzmannii extract
Lima_2020_Rev.Bras.Parasitol.Vet_29_e019819Anti-tick effect and cholinesterase inhibition caused by Prosopis juliflora alkaloids: in vitro and in silico studies
Lin_2020_Acta.Neuropathol.Commun_8_197A novel structure associated with aging is augmented in the DPP6-KO mouse brain
Lin_2020_BMC.Anesthesiol_20_246Cerebrospinal fluid cholinergic biomarkers are associated with postoperative delirium in elderly patients undergoing Total hip/knee replacement: a prospective cohort study
Lin_2020_Chem.Res.Toxicol_33_414Structure Dependent Determination of Organophosphate Targets in Mammalian Tissues Using Activity-Based Protein Profiling
Lin_2020_Food.Chem_345_128809Double-enzymes-mediated fluorescent assay for sensitive determination of organophosphorus pesticides based on the quenching of upconversion nanoparticles by Fe(3)
Lin_2020_Front.Microbiol_11_2045Degradation of Acephate and Its Intermediate Methamidophos: Mechanisms and Biochemical Pathways
Lin_2020_Front.Microbiol_11_573907Diverse Enzymes With Industrial Applications in Four Thraustochytrid Genera
Lin_2020_Front.Pharmacol_11_764Pharmacological Activity, Pharmacokinetics, and Toxicity of Timosaponin AIII, a Natural Product Isolated From Anemarrhena asphodeloides Bunge: A Review
Lin_2020_Neurotherapeutics_17_676Galantamine Inhibits Abeta(1-42)-Induced Neurotoxicity by Enhancing alpha7nAChR Expression as a Cargo Carrier for LC3 Binding and Abeta(1-42) Engulfment During Autophagic Degradation
Lin_2020_Theranostics_10_7857Protective effect of Soluble Epoxide Hydrolase Inhibition in Retinal Vasculopathy associated with Polycystic Kidney Disease
Linder_2020_EMBO.J__e105071CARD8 inflammasome activation triggers pyroptosis in human T cells
Ling_2020_Environ.Sci.Pollut.Res.Int__Effects of botanical pesticide itol A against the tobacco cutworm, Spodoptera litura (Fab.)
Linke_2020_Nat.Metab_2_1149A large-scale genome-lipid association map guides lipid identification
Lipinski_2020_Mol.Genet.Metab.Rep_23_100594Progressive macrophage accumulation in lysosomal acid lipase deficiency
Lipp_2020_Pharm.Res_37_34In Vitro and in Vivo Optimization of Phase Sensitive Smart Polymer for Controlled Delivery of Rivastigmine for Treatment of Alzheimer's Disease
Little_2020_ACS.Sustain.Chem.Eng_8_14471Effects of Methyl Branching on the Properties and Performance of Furandioate-Adipate Copolyesters of Bio-Based Secondary Diols
Littlejohn_2020_Elife_9_A feedback loop governs the relationship between lipid metabolism and longevity
Litvinenko_2020_Zh.Nevrol.Psikhiatr.Im.S.S.Korsakova_120_31[Cholinergic profile as a target of rational therapy of central nervous system diseases and injuries]
Liu_2020_Acta.Pharm.Sin.B_10_1926Interacting with alpha 7 nAChR is a new mechanism for AChE to enhance the inflammatory response in macrophages
Liu_2020_Aging.(Albany.NY)_12_Lemon essential oil ameliorates age-associated cognitive dysfunction via modulating hippocampal synaptic density and inhibiting acetylcholinesterase
Liu_2020_Anal.Chem_92_9205An Activity-Based Fluorogenic Probe Enables Cellular and in Vivo Profiling of Carboxylesterase Isozymes
Liu_2020_Analyst__Acetylcholinesterase-catalyzed silver deposition for ultrasensitive electrochemical biosensing of organophosphorus pesticides
Liu_2020_Ann.Hematol_99_2343LPL deletion is associated with poorer response to ibrutinib-based treatments and overall survival in TP53-deleted chronic lymphocytic leukemia
Liu_2020_Appl.Environ.Microbiol_87_Transcription Factor CfSte12 of Colletotrichum fructicola Is a Key Regulator of Early Apple Glomerella Leaf Spot Pathogenesis
Liu_2020_Biomed.Pharmacother_128_110314Lipase Inhibitors for Obesity: A Review
Liu_2020_Bioorg.Chem_103_104127Acylphloroglucinols with acetylcholinesterase inhibitory effects from the fruits of Eucalyptus robusta
Liu_2020_Bioorg.Chem_108_104579Corrigendum to Acylphloroglucinols with acetylcholinesterase inhibitory effects from the fruits of Eucalyptus robusta. [Bioorg. Chem. 103 (2020) 104127]
Liu_2020_Brain.Behav__e01602GAPT regulates cholinergic dysfunction and oxidative stress in the brains of learning and memory impairment mice induced by scopolamine
Liu_2020_Cell.Death.Differ__Monoglyceride lipase mediates tumor-suppressive effects by promoting degradation of X-linked inhibitor of apoptosis protein
Liu_2020_Chem.Biodivers__Polymethylated phloroglucinol meroterpenoids from Rhodomyrtus tomentosa and their antibacterial and acetylcholinesterase inhibitory effects
Liu_2020_Chem.Pharm.Bull.(Tokyo)_68_161Discovery and Biological Evaluation of New Selective Acetylcholinesterase Inhibitors with Anti-Abeta Aggregation Activity through Molecular Docking-Based Virtual Screening
Liu_2020_Chemosphere_240_124917Multilevel ecotoxicity assessment of environmentally relevant bisphenol F concentrations in Daphnia magna
Liu_2020_Chemosphere_252_126470Triphenyl phosphate permeates the blood brain barrier and induces neurotoxicity in mouse brain
Liu_2020_Chin.J.Integr.Med_26_577Efficacy and Safety of Guilingji Capsules () for Treating Mild-to-Moderate Cognitive Impairment: Study Protocol for A Randomized, Double-Blind, Positive-Controlled, Multicenter and Noninferiority Trial
Liu_2020_Colloids.Surf.B.Biointerfaces_197_111450Immobilization of thermophilic lipase in inorganic hybrid nanoflower through biomimetic mineralization
Liu_2020_Curr.Pharm.Des__Ajmalicine and its Analogues against AChE and BuChE for the Management of Alzheimer's Disease: An In-silico study
Liu_2020_Environ.Pollut_263_114463Per- and polyfluoroalkyl substances exert strong inhibition towards human carboxylesterases
Liu_2020_Environ.Pollut_265_114832Dietary administration of probiotic Lactobacillus rhamnosus modulates the neurological toxicities of perfluorobutanesulfonate in zebrafish
Liu_2020_Eur.J.Med.Chem__112997ROS-responsive and multifunctional anti-Alzheimer prodrugs: Tacrine-ibuprofen hybrids via a phenyl boronate linker
Liu_2020_Evid.Based.Complement.Alternat.Med_2020_5602597Neuroprotective Effects of D-(-)-Quinic Acid on Aluminum Chloride-Induced Dementia in Rats
Liu_2020_Food.Chem_324_126889Ultra-highly sensitive organophosphorus biosensor based on chitosan/tin disulfide and British housefly acetylcholinesterase
Liu_2020_Food.Funct_11_2328Acetylcholinesterase inhibitory activity and neuroprotection in vitro, molecular docking, and improved learning and memory functions of demethylcurcumin in scopolamine-induced amnesia ICR mice
Liu_2020_Front.Cell.Dev.Biol_8_570ABHD11 Is Critical for Embryonic Stem Cell Expansion, Differentiation and Lipid Metabolic Homeostasis
Liu_2020_Front.Chem_8_643Preparation of a Sensor Based on Biomass Porous Carbon/Covalent-Organic Frame Composites for Pesticide Residues Detection
Liu_2020_Front.Genet_11_741Analysis of a Chinese Pedigree With Familial Chylomicronemia Syndrome Reveals Two Novel LPL Mutations by Whole-Exome Sequencing
Liu_2020_Front.Immunol_11_619574Relief of Cadmium-Induced Intestinal Motility Disorder in Mice by Lactobacillus plantarum CCFM8610
Liu_2020_Front.Pharmacol_11_591854Predicting the Effects of CYP2C19 and Carboxylesterases on Vicagrel, a Novel P2Y12 Antagonist, by Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling Approach
Liu_2020_Front.Physiol_11_535722Post-exercise Effects and Long-Term Training Adaptations of Hormone Sensitive Lipase Lipolysis Induced by High-Intensity Interval Training in Adipose Tissue of Mice
Liu_2020_Gene__145027Identification of Oliver-McFarlane syndrome caused by novel compound heterozygous variants of PNPLA6
Liu_2020_Infect.Genet.Evol_85_104438Gene signatures of SARS-CoV/SARS-CoV-2-infected ferret lungs in short- and long-term models
Liu_2020_Insects_11_Enzymology, Histological and Ultrastructural Effects of Ar-Turmerone on Culex pipiens pallens Larvae
Liu_2020_Int.J.Biol.Macromol_163_1719Inhibitory kinetics and bioactivities of Nuciferine and Methyl Ganoderate on Mucor miehei lipase and 3T3-L1 preadipocytes
Liu_2020_Int.J.Ophthalmol_13_1361Acetylcholinesterase inhibition ameliorates retinal neovascularization and glial activation in oxygen-induced retinopathy
Liu_2020_J.Anal.Methods.Chem_2020_2971841Bioguided Isolation and Structure Identification of Acetylcholinesterase Enzyme Inhibitors from Drynariae Rhizome
Liu_2020_J.Ethnopharmacol__112983Resveratrol oligomers from Paeonia suffruticosa protect mice against cognitive dysfunction by regulating cholinergic, antioxidant and anti-inflammatory pathways
Liu_2020_J.Ginseng.Res_44_544Amino acid, fatty acid, and carbohydrate metabolomic profiles with ginsenoside-induced insecticidal efficacy against Ostrinia furnacalis (Guenee)
Liu_2020_J.Ind.Microbiol.Biotechnol_47_275Genomics-driven discovery of the biosynthetic gene cluster of maduramicin and its overproduction in Actinomadura sp. J1-007
Liu_2020_J.Mater.Chem.B_8_11001Ratiometric sensors with selective fluorescence enhancement effects based on photonic crystals for the determination of acetylcholinesterase and its inhibitor
Liu_2020_J.Sep.Sci__Extraction and Isolation of Acetylcholinesterase Inhibitors from Citrus limon Peel Using an in vitro Method
Liu_2020_Mikrochim.Acta_187_313Near-infrared emission tracks inter-individual variability of carboxylesterase-2 via a novel molecular substrate
Liu_2020_Mol.Plant_13_336The Chromosome-Based Rubber Tree Genome Provides New Insights into Spurge Genome Evolution and Rubber Biosynthesis
Liu_2020_Neurochem.Int__104931Supplementation with gamma-glutamylcysteine (gamma-GC) lessens oxidative stress, brain inflammation and amyloid pathology and improves spatial memory in a murine model of AD
Liu_2020_Oxid.Med.Cell.Longev_2020_1720961Neuregulin-1beta Protects the Rat Diaphragm during Sepsis against Oxidative Stress and Inflammation by Activating the PI3K/Akt Pathway
Liu_2020_PLoS.One_15_e0230335Three-dimensional brain-on-chip model using human iPSC-derived GABAergic neurons and astrocytes: Butyrylcholinesterase post-treatment for acute malathion exposure
Liu_2020_Sci.Total.Environ_713_136488Induced fluorescent enhancement of protein-directed synthesized gold nanoclusters for selective and sensitive detection of flame retardants
Liu_2020_Sci.Total.Environ_731_139136Differential responses of larval zebrafish to the fungicide propamocarb: Endpoints at development, locomotor behavior and oxidative stress
Liu_2020_Sci.Total.Environ__142630Enantioselective toxicity and oxidative stress effects of acetochlor on earthworms (Eisenia fetida) by mediating the signaling pathway
Liu_2020_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_247_119146A sensitive fluorescent assay for the determination of parathion-methyl using AHNSA probe with MnO(2) nanosheets
Liu_2020_Zhongguo.Zhong.Yao.Za.Zhi_45_2431[Virtual screen of effective AChE inhibitory constituents from Glycyrrhizae Radix et Rhizoma based on pharmacophore and molecular docking]
Liu_2020_Zhonghua.Lao.Dong.Wei.Sheng.Zhi.Ye.Bing.Za.Zhi_38_241[Predictive value of early detection of hs-cTnI and sST2 for secondary cardiac damage in severe acute organophosphorus pesticide poisoning]
Liwinski_2020_Am.J.Transplant_20_1482Harnessing the microbiota for therapeutic purposes
Lizarme-Salas_2020_Beilstein.J.Org.Chem_16_2663Vicinal difluorination as a C=C surrogate: an analog of piperine with enhanced solubility, photostability, and acetylcholinesterase inhibitory activity
Lo_2020_Sci.Rep_10_8911Inhibition of LIPG phospholipase activity suppresses tumor formation of human basal-like triple-negative breast cancer
Lock_2020_Toxicol.Res.(Camb)_9_591Inhibition of rat brain and human red cell acetylcholinesterase by thiocarbamate herbicides
Loften_2020_Addict.Biol__e12959An acetylcholine-dopamine interaction in the nucleus accumbens and its involvement in ethanol's dopamine-releasing effect
Loi_2020_Molecules_25_Intracellular Hydrolysis of Small-Molecule O-Linked N-Acetylglucosamine Transferase Inhibitors Differs among Cells and Is Not Required for Its Inhibition
Lolak_2020_Bioorg.Chem_100_103897Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, alpha-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs
Lolak_2020_J.Enzyme.Inhib.Med.Chem_35_424Sulphonamides incorporating 1,3,5-triazine structural motifs show antioxidant, acetylcholinesterase, butyrylcholinesterase, and tyrosinase inhibitory profile
Loncaric_2020_Chemosphere_247_125885Is nano ZnO/chlorpyrifos mixture more harmful to earthworms than bulk ZnO? A multigeneration approach
Long_2020_J.Cell.Physiol_235_3013LINC00205 modulates the expression of EPHX1 through the inhibition of miR-184 in hepatocellular carcinoma as a ceRNA
Longaretti_2020_J.Neurochem__e15000Termination of acute stress response by the endocannabinoid system is regulated through LSD1-mediated transcriptional repression of 2-AG hydrolases ABHD6 and MAGL
Lopes_2020_Bull.Environ.Contam.Toxicol__Correct Fish Muscle AChE Extraction for Use in Environmental Risk Assessment and Ecotoxicological Studies Has Been Neglected
Lopez-Arjona_2020_Res.Vet.Sci_133_26Changes in oxytocin concentrations in saliva of pigs after a transport and during lairage at slaughterhouse
Lopez_2020_Pharmaceuticals.(Basel)_13_Phytochemicals and Enzyme Inhibitory Capacities of the Methanolic Extracts from the Italian Apple Cultivar Mela Rosa dei Monti Sibillini
Lorke_2020_Molecules_25_Combined Pre- and Posttreatment of Paraoxon Exposure
Lotfi_2020_Bioorg.Chem_105_104457Design, synthesis and biological assessment of acridine derivatives containing 1,3,4-thiadiazole moiety as novel selective acetylcholinesterase inhibitors
Lou_2020_Fitoterapia__104550Polycyclic polyprenylated acylphloroglucinols with acetylcholinesterase inhibitory activities from Hypericum perforatum
Lu_2020_ACS.Omega_5_9806Global and Kinetic Profiles of Substrate Diffusion in Candida antarctica Lipase B: Molecular Dynamics with the Markov-State Model
Lu_2020_Circulation_142_1503Imaging Sarcoplasmic Reticulum Ca(2+) Signaling in Intact Cardiac Myocytes
Lu_2020_Drug.Dev.Res__Nitrogen-containing flavonoid and their analogs with diverse B-ring in acetylcholinesterase and butyrylcholinesterase inhibition
Lu_2020_Ecotoxicol.Environ.Saf_195_110517Degradation of dibutyl phthalate (DBP) by a bacterial consortium and characterization of two novel esterases capable of hydrolyzing PAEs sequentially
Lu_2020_Front.Immunol_11_1388A Novel alpha/beta Hydrolase Domain Protein Derived From Haemonchus contortus Acts at the Parasite-Host Interface
Lu_2020_J.Exp.Bot__MS1, a direct target of MS188, regulates the expression of key sporophytic pollen coat protein genes in Arabidopsis
Lu_2020_Nanoscale__Enhancing hydrogel-based long-lasting chemiluminescence by a platinum-metal organic framework and its application in array detection of pesticides and d-amino acids
Lu_2020_Neuromuscul.Disord__AChR myasthenia gravis switching to MuSK or double antibody positive myasthenia gravis in two children and literature review
Lucas_2020_J.Am.Mosq.Control.Assoc_36_22Oxidase, Esterase, and KDR-Associated Pyrethroid Resistance in Culex quinquefasciatus Field Collections of Collier County, Florida
Luchese_2020_Metab.Brain.Dis__Amnesia-ameliorative effect of a quinoline derivative through regulation of oxidative/cholinergic systems and Na(+)/K(+)-ATPase activity in mice
Ludtke_2020_Scand.J.Med.Sci.Sports__High-intensity swimming exercise reduces inflammatory pain in mice by activation of the endocannabinoid system
Lumley_2020_Neuropharmacol__108444Treatment of acetylcholinesterase inhibitor-induced seizures with polytherapy targeting GABA and glutamate receptors
Lumsden_2020_Neurotoxicol.Teratol__106914Learning and memory retention deficits in prepubertal guinea pigs prenatally exposed to low levels of the organophosphorus insecticide malathion
Lunic_2020_Molecules_25_Extracts Characterization and In Vitro Evaluation of Potential Immunomodulatory Activities of the Moss Hypnum cupressiforme Hedw
Luo_2020_BMC.Biol_18_118A molecular insight into the dissociable regulation of associative learning and motivation by the synaptic protein neuroligin-1
Luo_2020_Bioorg.Med.Chem__115400Design, synthesis and evaluation of phthalide alkyl tertiary amine derivatives as promising acetylcholinesterase inhibitors with high potency and selectivity against Alzheimer's disease
Lushchekina_2020_Biomolecules_10_Impact of Sucrose as Osmolyte on Molecular Dynamics of Mouse Acetylcholinesterase
Lushchekina_2020_Neuropharmacol__108236Slow-binding inhibitors of acetylcholinesterase of medical interest
Luz_2020_J.Lipid.Res_61_1347The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase
Lv_2020_Environ.Pollut_268_115847Cadmium exposure alters expression of protective enzymes and protein processing genes in venom glands of the wolf spider Pardosa pseudoannulata
Lv_2020_J.Dermatol_47_1445Novel small-insertion mutation in the LIPH gene in a patient with autosomal recessive woolly hair/hypotrichosis
Lyons_2020_Mol.Cell.Neurosci__103566Cannabinoid receptor subtype influence on neuritogenesis in human SH-SY5Y cells
Ma_2020_ACS.Appl.Mater.Interfaces_12_42119Stimulus Response of GQD-Sensitized Tb/GMP ICP Nanoparticles with Dual-Responsive Ratiometric Fluorescence: Toward Point-of-Use Analysis of Acetylcholinesterase and Organophosphorus Pesticide Poisoning with Acetylcholinesterase as a Biomarker
Ma_2020_ACS.Sens_5_83Near-Infrared Fluorescence Probe for Evaluating Acetylcholinesterase Activity in PC12 Cells and In Situ Tracing AChE Distribution in Zebrafish
Ma_2020_ACS.Sens__Correction to Near-Infrared Fluorescence Probe for Evaluating Acetylcholinesterase Activity in PC12 Cells and In Situ Tracing AChE Distribution in Zebrafish
Ma_2020_Anal.Chem_92_13405Observation of the elevation of cholinesterases activity in brain glioma by a near-infrared emission chemsensor
Ma_2020_Carbohydr.Res_491_107977Design, synthesis and biological evaluation of acridone glycosides as selective BChE inhibitors
Ma_2020_Drug.Discov.Today_25_1682Recent advances in multitarget-directed ligands targeting G-protein-coupled receptors
Ma_2020_J.Bone.Miner.Res__Brain-derived acetylcholine maintains peak bone mass in adult female mice
Ma_2020_J.Environ.Sci.Health.B__1Chronic trichlorfon stress induces differential transcriptome expression and interferes with multifunctional pathways in the brain of Rana chensinensis
Ma_2020_Med.Mycol_58_690Deletion of bem46 retards spore germination and may be related to the polar growth of Aspergillus fumigatus
Ma_2020_Mediators.Inflamm_2020_8829072Alterations in the Blood Parameters and Fecal Microbiota and Metabolites during Pregnant and Lactating Stages in Bama Mini Pigs as a Model
Ma_2020_Neuroreport_31_819Huperzine A inhibits heroin-seeking behaviors induced by cue or heroin priming in rats
Ma_2020_Pest.Manag.Sci_76_4000Evaluation of physiological and biochemical effects of two Sophora alopecuroides alkaloids on pea aphids Acyrthosiphon pisum
Ma_2020_Talanta_219_121278Rational design of a near-infrared fluorescence probe for highly selective sensing butyrylcholinesterase (BChE) and its bioimaging applications in living cell
Macha_2020_Comb.Chem.High.Throughput.Screen__Design, Synthesis and Biological Evaluation of New Cycloalkyl Fused Quinolines Tethered to Isatin Schiff Bases as Cholinesterase Inhibitors
Machado_2020_PLoS.One_15_e0232745The response of Synechococcus sp. PCC 7002 to micro-/nano polyethylene particles - Investigation of a key anthropogenic stressor
Machamer_2020_Arch.Toxicol_94_3877Functional basis for dose-dependent antagonism of rat and rabbit neuromuscular transmission by the bis-pyridinium oxime MMB4
Machani_2020_Sci.Rep_10_19063Phenotypic, genotypic and biochemical changes during pyrethroid resistance selection in Anopheles gambiae mosquitoes
Macharoen_2020_Int.J.Mol.Sci_21_Effects of Kifunensine on Production and N-Glycosylation Modification of Butyrylcholinesterase in a Transgenic Rice Cell Culture Bioreactor
Macht_2020_Neurobiol.Stress_12_100210Interactions between pyridostigmine bromide and stress on glutamatergic neurochemistry: Insights from a rat model of Gulf War Illness
Macklin_2020_Bioorg.Med.Chem.Lett__127213Synthesis, biochemical evaluation, and molecular modeling of organophosphate-coumarin hybrids as potent and selective butyrylcholinesterase inhibitors
Madi_2020_J.Ethnopharmacol__UPLC-Orbitrap HRMS metabolic profiling of Cymbopogon citratus cultivated in Egypt; neuroprotective effect against AlCl3-induced neurotoxicity in rats
Madi_2020_Nat.Prod.Res__1Essential oil of Cymbopogon citratus cultivated in Egypt: seasonal variation in chemical composition and anticholinesterase activity
Magdziarz_2020_Bioinformatics_36_2599AQUA-DUCT 1.0: structural and functional analysis of macromolecules from an intramolecular voids perspective
Magierski_2020_Front.Pharmacol_11_1168Pharmacotherapy of Behavioral and Psychological Symptoms of Dementia: State of the Art and Future Progress
Mahaboob Basha_2020_Toxicol.Rep_7_480Gestational and lactational exposition to di-n-butyl phthalate increases neurobehavioral perturbations in rats: A three generational comparative study
Mahajan_2020_Mol.Divers_24_1185Synthesis and biological evaluation of 1,2,4-triazolidine-3-thiones as potent acetylcholinesterase inhibitors: in vitro and in silico analysis through kinetics, chemoinformatics and computational approaches
Maher_2020_Life.Sci_247_117427Exogenous melatonin restrains neuroinflammation in high fat diet induced diabetic rats through attenuating indoleamine 2,3-dioxygenase 1 expression
Mahlooji_2020_Arch.Pharm.(Weinheim)__e2000052Discovery of phthalimide derivatives as novel inhibitors of a soluble epoxide hydrolase
Mahmoudi_2020_Neuropsychobiology__1Diosgenin Attenuates Cognitive Impairment in Streptozotocin-Induced Diabetic Rats: Underlying Mechanisms
Mahmud_2020_J.Basic.Clin.Physiol.Pharmacol__Ameliorative effect of methanol stem extract of Parquetina nigrescens (Afzel) bullock on scopolamine-induced sub-chronic cognitive deficit in mice
Mahomoodally_2020_Antioxidants.(Basel)_9_Bridelia speciosa Mull.Arg. Stem bark Extracts as a Potential Biomedicine: From Tropical Western Africa to the Pharmacy Shelf
Mahomoodally_2020_Curr.Pharm.Des__In silico exploration of bioactive phytochemicals against neurodegenerative diseases via inhibition of cholinesterases
Mahomoodally_2020_J.Pharm.Biomed.Anal_189_113477Phenolic compounds analysis of three Euphorbia species by LC-DAD-MS(n) and their biological properties
Mahomoodally_2020_Mar.Drugs_18_In Vitro Enzyme Inhibitory Properties, Secondary Metabolite Profiles and Multivariate Analysis of Five Seaweeds
Mahy_2020_J.Med.Chem_63_129425-Phenyl-1,3,4-oxadiazol-2(3H)-ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit
Mahy_2020_J.Med.Chem_63_9464Screening of a Custom-Designed Acid Fragment Library Identifies 1-Phenylpyrroles and 1-Phenylpyrrolidines as Inhibitors of Notum Carboxylesterase Activity
Maia_2020_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids__158807Impact of tetrahydrocannabinol on the endocannabinoid 2-arachidonoylglycerol metabolism: ABHD6 and ABHD12 as novel players in human placenta
Major_2020_Evol.Appl_13_620The G119S ace-1 mutation confers adaptive organophosphate resistance in a nontarget amphipod
Makhaeva_2020_Molecules_25_3915New Hybrids of 4-Amino-2,3-polymethylene-quinoline and p-Tolylsulfonamide as Dual Inhibitors of Acetyl- and Butyrylcholinesterase and Potential Multifunctional Agents for Alzheimer's Disease Treatment
Makhaeva_2020_Molecules_25_5891New Multifunctional Agents Based on Conjugates of 4-Amino-2,3-polymethylenequinoline and Butylated Hydroxytoluene for Alzheimer's Disease Treatment
Malamas_2020_Bioorg.Med.Chem_28_115195Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors
Malanotte_2020_J.Lasers.Med.Sci_11_56Low-Level Laser Effect on Peripheral Sciatic Regeneration Under the Systemic Inflammatory Condition of Periodontal Disease
Malekshahi_2020_Biotechnol.Appl.Biochem__Usage of peptidases by SARS-CoV-2 and several human coronaviruses as receptors: A mysterious story
Malinak_2020_J.Enzyme.Inhib.Med.Chem_35_478Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators
Malki_2020_Genet.Med__Loss-of-function variants in C3ORF52 result in localized autosomal recessive hypotrichosis
Mallick_2020_Toxicol.Sci_173_86Development and Application of a Life-Stage Physiologically Based Pharmacokinetic (PBPK) Model to the Assessment of Internal Dose of Pyrethroids in Humans
Malone_2020_Ther.Adv.Drug.Saf_11_2042098620942416QT interval prolongation and Torsades de Pointes with donepezil, rivastigmine and galantamine
Mamache_2020_J.Food.Biochem__e13472In vitro antioxidant, anticholinesterases, anti-alpha-amylase, and anti-alpha-glucosidase effects of Algerian Salvia aegyptiaca and Salvia verbenaca
Mamiya_2020_Biochem.Pharmacol__114139Galantamine improves enhanced impulsivity, impairments of attention and long-term potentiation induced by prenatal nicotine exposure to mice
Mamiya_2020_Enzyme.Microb.Technol_138_109546Significance of a family-6 carbohydrate-binding module in a modular feruloyl esterase for removing ferulic acid from insoluble wheat arabinoxylan
Man_2020_Brain.Res_1736_146782Donepezil promotes neurogenesis via Src signaling pathway in a rat model of chronic cerebral hypoperfusion
Manakhov_2020_Anim.Genet__The curly coat phenotype of the Ural Rex feline breed is associated with a mutation in the lipase H gene
Manasian_2020_Front.Microbiol_11_1534First Evidence of Acyl-Hydrolase/Lipase Activity From Human Probiotic Bacteria: Lactobacillus rhamnosus GG and Bifidobacterium longum NCC 2705
Mancheno_2020_Microb.Biotechnol__A structurally unique Fusobacterium nucleatum tannase provides detoxicant activity against gallotannins and pathogen resistance
Mangiagalli_2020_Int.J.Biol.Macromol_150_930Diverse effects of aqueous polar co-solvents on Candida antarctica lipase B
Mani_2020_Environ.Sci.Pollut.Res.Int_27_27358Chronic exposure to copper oxide nanoparticles causes muscle toxicity in adult zebrafish
Mansour_2020_Arch.Environ.Contam.Toxicol__Oxidative Stress and Damage Biomarkers in Clam Ruditapes decussatus Exposed to a Polluted Site: The Reliable Biomonitoring Tools in Hot and Cold Seasons
Manza_2020_Mol.Psychiatry_25_3256Brain structural changes in cannabis dependence: association with MAGL
Mao_2020_Insect.Sci__Carboxylesterase genes in nitenpyram-resistant brown planthoppers, Nilaparvata lugens
Mao_2020_Sci.Total.Environ_729_139031Embryonic development and oxidative stress effects in the larvae and adult fish livers of zebrafish (Danio rerio) exposed to the strobilurin fungicides, kresoxim-methyl and pyraclostrobin
Marakovic_2020_Biochem.J_477_2771Enantioseparation, in vitro testing, and structural characterization of triple-binding reactivators of organophosphate-inhibited cholinesterases
Maramai_2020_Biomed.Res.Int_2020_5120230Multitarget Therapeutic Strategies for Alzheimer's Disease: Review on Emerging Target Combinations
Marasco_2020_Am.J.Manag.Care_26_S167Current and evolving treatment strategies for the Alzheimer disease continuum
Marchi_2020_ACS.Omega_5_3504Synthesis, Characterization, and Low-Toxicity Study of a Magnesium(II) Complex Containing an Isovanillate Group
Marek_2020_Comput.Struct.Biotechnol.J_18_1352Structural and catalytic effects of surface loop-helix transplantation within haloalkane dehalogenase family
Margaritopoulos_2020_Bull.Entomol.Res__1Long-term studies on the evolution of resistance of Myzus persicae (Hemiptera: Aphididae) to insecticides in Greece
Margulis_2020_Life.(Basel)_10_Over Expression of the Cyanobacterial Pgr5-Homologue Leads to Pseudoreversion in a Gene Coding for a Putative Esterase in Synechocystis 6803
Marikova_2020_J.Nat.Prod__Aromatic Esters of the Crinane Amaryllidaceae Alkaloid Ambelline as Selective Inhibitors of Butyrylcholinesterase
Markova_2020_Chem.Sci_11_11162Decoding the intricate network of molecular interactions of a hyperstable engineered biocatalyst
Markovic_2020_Int.J.Mol.Sci_21_Computational Simulations to Guide Enzyme-Mediated Prodrug Activation
Marotta_2020_Molecules_25_Memantine Derivatives as Multitarget Agents in Alzheimer's Disease
Marques_2020_Bioorg.Chem_98_103753N-1,2,3-triazole-isatin derivatives for cholinesterase and beta-amyloid aggregation inhibition: A comprehensive bioassay study
Marrero-Rosado_2020_Epilepsy.Behav_111_107229Ketamine as adjunct to midazolam treatment following soman-induced status epilepticus reduces seizure severity, epileptogenesis, and brain pathology in plasma carboxylesterase knockout mice
Marsavelski_2020_Int.J.Biol.Macromol_158_222The substrate selectivity of the two homologous SGNH hydrolases from Streptomyces bacteria: Molecular dynamics and experimental study
Marsillach_2020_Antioxidants.(Basel)_9_HDL Proteome and Alzheimer's Disease: Evidence of a Link
Martinez-Morcillo_2020_Int.J.Hyg.Environ.Health_223_10Presence of pharmaceutical compounds, levels of biochemical biomarkers in seafood tissues and risk assessment for human health: Results from a case study in North-Western Spain
Martinez-Perez_2020_Folia.Microbiol.(Praha)__Exoenzyme-producing halophilic bacteria from the former Lake Texcoco: identification and production of n-butyl oleate and bioactive peptides
Martinez_2020_Int.J.Mol.Sci_21_Deletion and Randomization of Structurally Variable Regions in B. subtilis Lipase A (BSLA) Alter Its Stability and Hydrolytic Performance Against Long Chain Fatty Acid Esters
Martinuzzi_2020_Bull.Environ.Contam.Toxicol_104_35Comparative Toxicity of Two Different Dimethoate Formulations in the Common Toad (Rhinella arenarum) Tadpoles
Mascarenhas_2020_J.Biomol.Struct.Dyn__1Pharmacophore-based virtual screening and molecular docking to identify promising dual inhibitors of human acetylcholinesterase and butyrylcholinesterase
Maspero_2020_Bioorg.Chem_96_103633Tacrine-xanomeline and tacrine-iperoxo hybrid ligands: Synthesis and biological evaluation at acetylcholinesterase and M1 muscarinic acetylcholine receptors
Mathew_2020_Comb.Chem.High.Throughput.Screen_23_834Inhibitors of Monoamine Oxidase and Acetylcholinesterase as a Front Runner in CNS Drug Discovery
Mathew_2020_Comb.Chem.High.Throughput.Screen__Privileged Pharmacophore of FDA Approved Drugs in Combination with Chalcone Framework: A New Hope for Alzheimer's Treatment
Mathew_2020_J.Biomol.Struct.Dyn__1Development of methylthiosemicarbazones as new reversible monoamine oxidase-B inhibitors for the treatment of Parkinson's disease
Matin_2020_Microcirculation__e12653Soluble Epoxide Hydrolase Inhibition Improves Cognitive Function and Parenchymal Artery Dilation in a Hypertensive Model of Chronic Cerebral Hypoperfusion
Matos_2020_Hum.Gene.Ther__Development of an antisense oligonucleotide-mediated exon skipping therapeutic strategy for Mucolipidosis II: validation at RNA level
Matosevic_2020_Arh.Hig.Rada.Toksikol_71_285Carbamate group as structural motif in drugs: a review of carbamate derivatives used as therapeutic agents
Matsuda_2020_Anal.Bioanal.Chem__Imaging mass spectrometry to visualise increased acetylcholine in lungs of asthma model mice
Matsumoto_2020_Cancer.Chemother.Pharmacol__Variants of carboxylesterase 1 have no impact on capecitabine pharmacokinetics and toxicity in capecitabine plus oxaliplatin treated-colorectal cancer patients
Matsushita_2020_Chemosphere_261_127743Effect of chlorination on anti-acetylcholinesterase activity of organophosphorus insecticide solutions and contributions of the parent insecticides and their oxons to the activity
Matta_2020_Sci.Rep_10_14492An altered glial phenotype in the NL3(R451C) mouse model of autism
Maurya_2020_Biochimie_179_113MetA (Rv3341) from Mycobacterium tuberculosis H37Rv strain exhibits substrate dependent dual role of transferase and hydrolase activity
Maurya_2020_Front.Bioeng.Biotechnol_8_602325Enzymatic Remediation of Polyethylene Terephthalate (PET)-Based Polymers for Effective Management of Plastic Wastes: An Overview
Maxeiner_2020_Mol.Biol.Evol__Evolution of the Autism-Associated Neuroligin-4 Gene Reveals Broad Erosion of Pseudoautosomal Regions in Rodents
Mayasankaravalli_2020_Saudi.J.Biol.Sci_27_3228Profiling the phyto-constituents of Punica granatum fruits peel extract and accessing its in-vitro antioxidant, anti-diabetic, anti-obesity, and angiotensin-converting enzyme inhibitory properties
Mayer_2020_Bioorg.Med.Chem_28_115610Structure-activity relationship studies for the development of inhibitors of murine adipose triglyceride lipase (ATGL)
Mazaheri_2020_Int.J.Reprod.Biomed_18_785Effects of phosalone plant pesticide on sperm parameters and sexual hormone levels in Wistar rats: An experimental study
Mazumder_2020_Med.Hypotheses_137_109544Inhibitory potential of plant secondary metabolites on anti-Parkinsonian drug targets: Relevance to pathophysiology, and motor and non-motor behavioural abnormalities
Mbah Ntepe_2020_Int.J.Mol.Sci_21_Oxidative Stress and Analysis of Selected SNPs of ACHE (rs 2571598), BCHE (rs 3495), CAT (rs 7943316), SIRT1 (rs 10823108), GSTP1 (rs 1695), and Gene GSTM1, GSTT1 in Chronic Organophosphates Exposed Groups from Cameroon and Pakistan
Mbelu_2020_Pan.Afr.Med.J_37_314[Frequency of hyperlipasemia in patients with bone fractures on follow up at the Military General Hospital in camp Kokolo]
McClafferty_2020_J.Biol.Chem_295_16487Site specific deacylation by ABHD17a controls BK channel splice variant activity
McComic_2020_Pestic.Biochem.Physiol_169_104652Reduced neuronal sensitivity and susceptibility of the fall armyworm, Spodoptera frugiperda, to pyrethroids in the absence of known knockdown mutations
McDiarmid_2020_Proc.Natl.Acad.Sci.U.S.A_117_656Systematic phenomics analysis of autism-associated genes reveals parallel networks underlying reversible impairments in habituation
McGarry_2020_Toxicol.Sci_174_124Characterization of Cholinesterases from Multiple Large Animal Species for Medical Countermeasure Development against Chemical Warfare Nerve Agents
McGarry_2020_Toxicol.Sci_174_133A Novel, Modified Human Butyrylcholinesterase Catalytically Degrades the Chemical Warfare Nerve Agent, Sarin
McNabb-Baltar_2020_Am.J.Gastroenterol__Lipase Elevation in Patients With COVID-19
McPherson_2020_Curr.Enzym.Inhib_16_The Crystal Structures of Thermomyces (Humicola) Lanuginosa Lipase in Complex with Enzymatic Reactants
McReynolds_2020_Adv.Exp.Med.Biol_1274_71Epoxy Fatty Acids Are Promising Targets for Treatment of Pain, Cardiovascular Disease and Other Indications Characterized by Mitochondrial Dysfunction, Endoplasmic Stress and Inflammation
Mckernan_2020_bioRxiv__Sequence and annotation of 42 cannabis genomes reveals extensive copy number variation in cannabinoid synthesis and pathogen resistance genes
Mechri_2020_Environ.Sci.Pollut.Res.Int__A biological clean processing approach for the valorization of speckled shrimp Metapenaeus monoceros by-product as a source of bioactive compounds
Medeiros_2020_Int.J.Dev.Neurosci_80_636Single exercise stress reduces central neurotrophins levels and adenosine A(1) and A(2) receptors expression, but does not revert opioid-induced hyperalgesia in rats
Meden_2020_Eur.J.Med.Chem_208_112766Structure-activity relationship study of tryptophan-based butyrylcholinesterase inhibitors
Medina-Vera_2020_Biology.(Basel)_9_Imbalance of Endocannabinoid/Lysophosphatidylinositol Receptors Marks the Severity of Alzheimer's Disease in a Preclinical Model: A Therapeutic Opportunity
Medithi_2020_Arch.Environ.Occup.Health__1Organophosphate pesticide exposure among farm women and children: Status of micronutrients, acetylcholinesterase activity, and oxidative stress
Mehla_2020_Brain.Sci_10_Indian Medicinal Herbs and Formulations for Alzheimer's Disease, from Traditional Knowledge to Scientific Assessment
Mehrazar_2020_Mol.Divers_24_997Design and synthesis of benzodiazepine-1,2,3-triazole hybrid derivatives as selective butyrylcholinesterase inhibitors
Meier_2020_Angew.Chem.Int.Ed.Engl__Prodrugs of gamma-Alkyl-modified Nucleoside Triphosphates - improved Inhibition of HIV Reverse Transcriptase
Mejri_2020_Food.Chem_333_127506Phytochemical analysis and in vitro and in vivo evaluation of biological activities of artichoke (Cynara scolymus L.) floral stems: Towards the valorization of food by-products
Menden_2020_Biomed.Pharmacother_130_110579Candida rugosa lipase alters the gastrointestinal environment in wild-type mice
Meng_2020_Environ.Pollut_265_114824Mosquito larvae that survive a heat spike are less sensitive to subsequent exposure to the pesticide chlorpyrifos
Meng_2020_Environ.Sci.Technol_54_11476The Exposure Order Strongly Modifies How a Heat Spike Increases Pesticide Toxicity
Meng_2020_J.Hazard.Mater_410_124811Two birds with one stone: The detection of nerve agents and AChE activity with an ICT-ESIPT-based fluorescence sensor
Mettupalayam_2020_BMC.Complement.Med.Ther_20_129In vitro enzyme inhibitory and cytotoxic studies with Evolvulus alsinoides (Linn.) Linn. Leaf extract: a plant from Ayurveda recognized as Dasapushpam for the management of Alzheimer's disease and diabetes mellitus
Meyburg_2020_Pediatr.Crit.Care.Med_21_535Cholinesterases and Anticholinergic Medications in Postoperative Pediatric Delirium
Meyer-Cifuentes_2020_Nat.Commun_11_5790Synergistic biodegradation of aromatic-aliphatic copolyester plastic by a marine microbial consortium
Mezeiova_2020_Bioorg.Chem_103_104179From orexin receptor agonist YNT-185 to novel antagonists with drug-like properties for the treatment of insomnia
Mhadhbi_2020_Drug.Chem.Toxicol__1Azithromycin effects on the European sea bass (Dicentrarchus labrax) early life stages following acute and chronic exposure: Laboratory bioassays
Miao_2020_BMC.Complement.Med.Ther_20_256The toxicity assessment of extract of Peganum harmala L. seeds in Caenorhabditis elegans
Miao_2020_Insect.Biochem.Mol.Biol__103457Digestion-related proteins in the tobacco hornworm, Manduca sexta
Michalea_2020_J.Ethnopharmacol_257_111547Efficient identification of Acetylcholinesterase and Hyaluronidase inhibitors from Paeonia parnassica extracts through a HeteroCovariance Approach
Michalovicz_2020_Neuropharmacol__108073Acetylcholinesterase inhibitor exposures as an initiating factor in the development of Gulf War Illness, a chronic neuroimmune disorder in deployed veterans
Michalska_2020_Antioxidants.(Basel)_9_Antioxidant, Anti-inflammatory and Neuroprotective Profiles of Novel 1,4-Dihydropyridine Derivatives for the Treatment of Alzheimer's Disease
Miguel_2020_Commun.Biol_3_746Author Correction: A GDSL lipase-like from Ipomoea batatas catalyzes efficient production of 3,5-diCQA when expressed in Pichia pastoris
Mihajilov-Krstev_2020_Plants.(Basel)_9_Phytochemistry, Toxicology and Therapeutic Value of Petasites hybridus Subsp. Ochroleucus (Common Butterbur) from the Balkans
Miladinovic_2020_Chem.Biol.Interact__109312Recovery of brain cholinesterases and effect on parameters of oxidative stres and apoptosis in quails (Coturnix japonica) after chlorpyrifos and vitamin B1 administration
Miles_2020_Bioorg.Med.Chem.Lett__127609Rapid discovery of a selective butyrylcholinesterase inhibitor using structure-based virtual screening
Millan_2020_Neuropharmacol__108099Dual-acting agents for improving cognition and real-world function in Alzheimer's disease: Focus on 5-HT6 and D3 receptors as hubs
Miller_2020_Exp.Eye.Res__108266Endocannabinoid metabolism and transport as targets to regulate intraocular pressure
Milone_2020_Ecotoxicol.Environ.Saf_206_111213Differences in larval pesticide tolerance and esterase activity across honey bee (Apis mellifera) stocks
Milosevic_2020_Bioorg.Chem_102_104073Synthesis, characterization and SAR studies of bis(imino)pyridines as antioxidants, acetylcholinesterase inhibitors and antimicrobial agents
Mimura_2020_BMC.Neurol_20_183Pisa syndrome induced by switching of a choline-esterase inhibitor treatment from donepezil to galantamine: a case report
Minamizuka_2020_Clin.Chim.Acta_510_216Detailed analysis of lipolytic enzymes in a Japanese woman of familial lipoprotein lipase deficiency - Effects of pemafibrate treatment
Mine_2020_Anal.Methods_12_5846Kinetic analysis of an enzymatic hydrolysis of p-nitrophenyl acetate with carboxylesterase by pressure-assisted capillary electrophoresis/dynamic frontal analysis
Miranda_2020_Parasitol.Res_119_333Renin angiotensin system molecules and nitric oxide local interactions in the adrenal gland of Trypanosoma cruzi infected rats
Mironova_2020_Eur.Rev.Med.Pharmacol.Sci_24_8585Prospects for the use of regulators of oxidative stress in the comprehensive treatment of the novel Coronavirus Disease 2019 (COVID-19) and its complications
Mirzaie_2020_Drug.Des.Devel.Ther_14_3589Enhancing the Butyrylcholinesterase Activity in HEK-293 Cell Line by Dual-Promoter Vector Decorated on Lipofectamine
Mishra_2020_Chemosphere_259_127419Carbofuran toxicity and its microbial degradation in contaminated environments
Mishra_2020_Drug.Chem.Toxicol__1Acute toxic effects of chlorpyrifos on pseudobranchial neurosecretory system, brain regions and locomotory behavior of an air-breathing catfish, Heteropneustes fossilis (Bloch 1794)
Missawi_2020_Environ.Pollut_263_114634Abundance and distribution of small microplastics (> 3 microm) in sediments and seaworms from the Southern Mediterranean coasts and characterisation of their potential harmful effects
Mitsuboshi_2020_Biol.Pharm.Bull_43_1275Effect of Patient Age, Dose, and Chronic Kidney Disease on the Risk of Adverse Reactions to Distigmine
Mitusiska_2020_Int.J.Mol.Sci_21_Simple Selection Procedure to Distinguish between Static and Flexible Loops
Miyashita_2020_J.Lipid.Res_61_1365Chylomicronemia from GPIHBP1 autoantibodies
Miyauchi_2020_Yonago.Acta.Med_63_335Comparisons of Postoperative Complications and Nutritional Status After Proximal Laparoscopic Gastrectomy with Esophagogastrostomy and Double-Tract Reconstruction
Miyoshi_2020_Nutrition_79-80_110957Urinary titin N-terminal fragment concentration is an indicator of preoperative sarcopenia and nutritional status in patients with gastrointestinal tract and hepatobiliary pancreatic malignancies
Mizrak_2020_Cell.Rep_31_107805Single-Cell Profiling and SCOPE-Seq Reveal Lineage Dynamics of Adult Ventricular-Subventricular Zone Neurogenesis and NOTUM as a Key Regulator
Mizuno_2020_Biorxiv__Major components in the KARRIKIN INSENSITIVE2-ligand signaling pathway are conserved in the liverwort, Marchantia polymorpha
Mkhinini_2020_Ecotoxicology_29_1003Earthworm Eisenia andrei modulates oxidative stress in bean plants Vicia faba irrigated with treated wastewater
Mo_2020_J.Enzyme.Inhib.Med.Chem_35_330Design, synthesis, in vitro and in vivo evaluation of benzylpiperidine-linked 1,3-dimethylbenzimidazolinones as cholinesterase inhibitors against Alzheimer's disease
Modahl_2020_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_232_108743Interspecific and intraspecific venom enzymatic variation among cobras (Naja sp. and Ophiophagus hannah)
Mogami_2020_Evid.Based.Complement.Alternat.Med_2020_3797219Usefulness of a Kampo Medicine on Stress-Induced Delayed Gastric Emptying in Mice
Mogodiniyai_2020_Microbiolopen_9_e971Does glucose affect the de-esterification of methyl ferulate by Lactobacillus buchneri?
Mohamed_2020_Int.J.Biol.Macromol_147_1029Purification and characterization of acetylcholinesterase in Rhynchophorus ferrugineus (Olivier) (Coleoptera: Curculionidae)
Mohamed_2020_J.Ethnopharmacol__113468Sesame oil mitigates memory impairment, oxidative stress, and neurodegeneration in a rat model of Alzheimer's disease. A pivotal role of NF-kappaB/p38MAPK/BDNF/PPAR-gamma pathways
Mohamed_2020_J.Med.Food__Maillard Reaction Products and Phenolic Compounds from Roasted Peanut Flour Extracts Prevent Scopolamine-Induced Amnesia Via Cholinergic Modulation and Antioxidative Effects in Mice
Mohamed_2020_Prog.Lipid.Res__101067The multi-faces of Angptl8 in health and disease: Novel functions beyond lipoprotein lipase modulation
Mohammed_2020_Biochim.Biophys.Acta.Mol.Basis.Dis__165665Protective effect of curcumin nanoparticles against cardiotoxicity induced by doxorubicin in rat
Mohammed_2020_Biol.Trace.Elem.Res_196_579Grape Seed Proanthocyanidin Extract Mitigates Titanium Dioxide Nanoparticle (TiO(2)-NPs)-Induced Hepatotoxicity Through TLR-4/NF-B Signaling Pathway
Mohammed_2020_Curr.Pharm.Biotechnol__Oral Supplements of Ginkgo biloba Extract Alleviate Neuroinflammation, Oxidative Impairments and Neurotoxicity in Rotenone-Induced Parkinsonian Rats
Mohan_2020_Toxicol.Lett_335_91Danio rerio as an alternative vertebrate model for jellyfish venom study: The toxinological aspects of Nemopilema nomurai venom
Mohanan_2020_Front.Microbiol_11_580709Microbial and Enzymatic Degradation of Synthetic Plastics
Moharana_2020_PLoS.One_15_e0231177Substrate structure and computation guided engineering of a lipase for omega-3 fatty acid selectivity
Mohd_2020_Arch.Pharm.(Weinheim)__e2000161In silico studies, nitric oxide, and cholinesterases inhibition activities of pyrazole and pyrazoline analogs of diarylpentanoids
Mokrushina_2020_Proc.Natl.Acad.Sci.U.S.A_117_22841Multiscale computation delivers organophosphorus reactivity and stereoselectivity to immunoglobulin scavengers
Molina-Pintor_2020_Environ.Sci.Pollut.Res.Int__Relationship between butyrylcholinesterase activity and lipid parameters in workers occupationally exposed to pesticides
Molitor_2020_Microb.Biotechnol_13_274Agar plate-based screening methods for the identification of polyester hydrolysis by Pseudomonas species
Mondal_2020_ACS.Catal_10_6002Combinatorial Approach for Exploring Conformational Space and Activation Barriers in Computer-Aided Enzyme Design
Monsalve_2020_PLoS.ONE_15_E0225672Purification and molecular characterization of phospholipase, antigen 5 and hyaluronidases from the venom of the Asian hornet (Vespa velutina)
Montali_2020_Biosens.Bioelectron_162_112232Multienzyme chemiluminescent foldable biosensor for on-site detection of acetylcholinesterase inhibitors
Montalvao_2020_Sci.Total.Environ_756_143991Carbon nanofibers are bioaccumulated in Aphylla williamsoni (Odonata) larvae and cause REDOX imbalance and changes of acetylcholinesterase activity
Monteiro_2020_J.Econ.Entomol__Evaluation of Resistance Management for the Oriental Fruit Moth (Lepidoptera: Tortricidae) to Insecticides in Brazilian Apple Orchards
Moon_2020_EJNMMI.Radiopharm.Chem_5_19Targeting fibroblast activation protein (FAP): next generation PET radiotracers using squaramide coupled bifunctional DOTA and DATA(5m) chelators
Morandi_2020_J.Am.Med.Dir.Assoc_21_486Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia
Morato_2020_Angew.Chem.Int.Ed.Engl_59_20459High-Throughput Label-Free Enzymatic Assays Using Desorption Electrospray-Ionization Mass Spectrometry
Moreira_2020_Chemosphere_263_127972Fipronil and 2,4-D effects on tropical fish: Could avoidance response be explained by changes in swimming behavior and neurotransmission impairments?
Moreira_2020_Ecotoxicology__Effects of abamectin-based and difenoconazole-based formulations and their mixtures in Daphnia magna: a multiple endpoint approach
Moreira_2020_Heliyon_6_e04030Biomarkers responses of the clam Anomalocardia flexuosa in sediment toxicity bioassays using dredged materials from a semi-arid coastal system
Moreira_2020_J.Alzheimers.Dis_78_353Novel Hybrid Acetylcholinesterase Inhibitors Induce Differentiation and Neuritogenesis in Neuronal Cells in vitro Through Activation of the AKT Pathway
Moren_2020_Adipocyte_9_636Surface-associated lipid droplets: an intermediate site for lipid transport in human adipocytes?
Moreno-Cordova_2020_Biophys.Chem_264_106409Gallotannins are uncompetitive inhibitors of pancreatic lipase activity
Moreno_2020_Molecules_25_Chemical Profiling and Cholinesterase Inhibitory Activity of Five Phaedranassa Herb. (Amaryllidaceae) Species from Ecuador
Morfin_2020_Biology.(Basel)_9_The Combined Effects of Varroa destructor Parasitism and Exposure to Neonicotinoids Affects Honey Bee (Apis mellifera L.) Memory and Gene Expression
Mori_2020_Phytochemistry_174_112349Chemical identification of 18-hydroxycarlactonoic acid as an LjMAX1 product and in planta conversion of its methyl ester to canonical and non-canonical strigolactones in Lotus japonicus
Mori_2020_Planta_251_40Identification of two oxygenase genes involved in the respective biosynthetic pathways of canonical and non-canonical strigolactones in Lotus japonicus
Morozova_2020_J.Evol.Biochem.Physiol_56_531Effect of Prenatal Hypoxia on Activity of the Soluble Forms of Cholinesterases in Rat Brain Structures during Early Postnatal Ontogenesis
Moshitzky_2020_Biomolecules_10_Cholinergic Stress Signals Accompany MicroRNA-Associated Stereotypic Behavior and Glutamatergic Neuromodulation in the Prefrontal Cortex
Moss_2020_Int.J.Mol.Sci_21_Improving Anti-Neurodegenerative Benefits of Acetylcholinesterase Inhibitors in Alzheimer's Disease: Are Irreversible Inhibitors the Future?
Mota_2020_Bioresour.Technol_307_123223Production of low-calorie structured lipids from spent coffee grounds or olive pomace crude oils catalyzed by immobilized lipase in magnetic nanoparticles
Motavalli_2020_Mult.Scler.Relat.Disord_46_102478Pharmacotherapy in multiple sclerosis-induced cognitive impairment: A systematic review and meta-analysis
Motawi_2020_ACS.Chem.Neurosci_11_3386Ameliorative Effect of Necrosulfonamide in a Rat Model of Alzheimer's Disease: Targeting Mixed Lineage Kinase Domain-like Protein-Mediated Necroptosis
Motawi_2020_Mol.Cell.Biochem_465_89Potential therapeutic effects of antagonizing adenosine A2A receptor, curcumin and niacin in rotenone-induced Parkinson's disease mice model
Moussa_2020_Heliyon_6_e05019Preparation and biological assessment of some aromatic hydrazones derived from hydrazides of phenolic acids and aromatic aldehydes
Mozaffarnia_2020_Eur.J.Med.Chem_191_112140Design, synthesis and biological evaluation of 2,3-dihydro-5,6-dimethoxy-1H-inden-1-one and piperazinium salt hybrid derivatives as hAChE and hBuChE enzyme inhibitors
Mroczek_2020_Metabolites_10_The Bioassay-Guided Fractionation and Identification of Potent Acetylcholinesterase Inhibitors from Narcissus c.v. 'Hawera' Using Optimized Vacuum Liquid Chromatography, High Resolution Mass Spectrometry and Bioautography
Mroueh_2020_Bioorg.Chem_100_103895Synthesis, biological evaluation and modeling of hybrids from tetrahydro-1H-pyrazolo[3,4-b]quinolines as dual cholinestrase and COX-2 inhibitors
Muanda_2020_Clin.J.Am.Soc.Nephrol_15_1728Higher-Dose Sitagliptin and the Risk of Congestive Heart Failure in Older Adults with CKD
Mughal_2020_J.Biomol.Struct.Dyn__1Exploring 3-Benzyloxyflavones as new lead cholinesterase inhibitors: synthesis, structure-activity relationship and molecular modelling simulations
Mukaida_2020_Gen.Thorac.Cardiovasc.Surg_68_585Free triiodothyronine (fT3) and B-type natriuretic peptide (BNP) predict in-hospital mortality after valve surgery
Mukherjee_2020_J.Toxicol_2020_3007984Organophosphorus Nerve Agents: Types, Toxicity, and Treatments
Muldoon_2020_Neuropharmacol__108170Inhibition of monoacylglycerol lipase reduces nicotine reward in the conditioned place preference test in male mice
Mulinari_2020_Biotechnol.Adv__107581Lipase immobilization on ceramic supports: An overview on techniques and materials
Muller_2020_Angew.Chem.Int.Ed.Engl_59_11607Sequence-Based Prediction of Promiscuous Acyltransferase Activity in Hydrolases
Muller_2020_Chem.Biol.Interact__108959Contribution of cholinergic system and Nrf2/HO-1 signaling to the anti-amnesic action of 7-fluoro-1,3-diphenylisoquinoline-1-amine in mice
Munawar_2020_Pak.J.Pharm.Sci_33_659Molecular docking, synthesis and biological evaluation of phenacyl derivatives of 9-aminoacridine as anti-Alzheimer's agent
Munford_2020_J.Biol.Chem__Biochemical Transformation of Bacterial Lipopolysaccharide by acyloxyacyl hydrolase reduces host injury and promotes recovery
Munoz-Penuela_2020_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__108910Diclofenac and caffeine inhibit hepatic antioxidant enzymes in the freshwater fish Astyanax altiparanae (Teleostei: Characiformes)
Mus_2020_Biochem.J_477_2027Insights into the unique carboxylation reactions in the metabolism of propylene and acetone
Musachio_2020_Food.Chem.Toxicol_137_111128Bisphenol A exposure is involved in the development of Parkinson like disease in Drosophila melanogaster
Musarurwa_2020_Chemosphere_266_129222Extraction and electrochemical sensing of pesticides in food and environmental samples by use of polydopamine-based materials
Musayeib_2020_Molecules_25_Plectrabarbene, a New Abietane Diterpene from Plectranthus barbatus Aerial Parts
Muszalska-Kolos_2020_Molecules_25_Tricyclic Derivative of Acyclovir and Its Esters in Relation to the Esters of Acyclovir Enzymatic Stability: Enzymatic Stability Study
Myrtollari_2020_Bioorg.Chem_104_104214Activity and specificity studies of the new thermostable esterase EstDZ2
Na_2020_J.Proteome.Res_19_4867Potential Regulatory Role of Human-Carboxylesterase-1 Glycosylation in Liver Cancer Cell Growth
Nachon_2020_Molecules_25_1198A Second Look at the Crystal Structures of Drosophila melanogaster Acetylcholinesterase in Complex with Tacrine Derivatives Provides Insights Concerning Catalytic Intermediates and the Design of Specific Insecticides
Nagaroor_2020_J.Ind.Microbiol.Biotechnol_47_169Biochemical characterization of an esterase from Clostridium acetobutylicum with novel GYSMG pentapeptide motif at the catalytic domain
Naharci_2020_J.Am.Med.Dir.Assoc_21_706Comment on Association Between Acetylcholinesterase Inhibitors and Osteoporotic Fractures in Alzheimer's Patients
Naik_2020_Chem.Biol.Interact__109225Monoclonal antibodies to fetal bovine serum acetylcholinesterase distinguish between acetylcholinesterases from ruminant and non-ruminant species
Naime_2020_Neurotox.Res_38_603Glutathione in Chlorpyrifos-and Chlorpyrifos-Oxon-Induced Toxicity: a Comparative Study Focused on Non-cholinergic Toxicity in HT22 Cells
Naito_2020_J.Am.Soc.Mass.Spectrom_31_2154Feasibility of Acetylcholinesterase Reaction Assay Monitoring in DIUTHAME-MS
Nakajima_2020_Transl.Psychiatry_10_407Ntrk1 mutation co-segregating with bipolar disorder and inherited kidney disease in a multiplex family causes defects in neuronal growth and depression-like behavior in mice
Nakamura_2020_Molecules_25_Trimethyl-Substituted Carbamate as a Versatile Self-Immolative Linker for Fluorescence Detection of Enzyme Reactions
Nakatsu_2020_Metabolism__154459Prolyl isomerase Pin1 interacts with adipose triglyceride lipase and negatively controls both its expression and lipolysis
Nam_2020_Chem.Sci_11_10243Multiple reactivities of flavonoids towards pathological elements in Alzheimer's disease: structure-activity relationship
Namountougou_2020_Trop.Med.Infect.Dis_5_Monitoring Insecticide Susceptibility in Aedes Aegypti Populations from the Two Biggest Cities, Ouagadougou and Bobo-Dioulasso, in Burkina Faso: Implication of Metabolic Resistance
Naparlo_2020_Molecules_25_Interaction of Catechins with Human Erythrocytes
Napiorkowska_2020_Small__e2005523High-Throughput Optimization of Recombinant Protein Production in Microfluidic Gel Beads
Nartop_2020_J.Environ.Sci.Health.B__1Qualitative enzymatic detection of organophosphate and carbamate insecticides
Nasr_2020_Polymers.(Basel)_12_Enzymatic Polycondensation of 1,6-Hexanediol and Diethyl Adipate: A Statistical Approach Predicting the Key-Parameters in Solution and in Bulk
Nasreen_2020_Exp.Appl.Acarol_82_281The potential of Allium sativum and Cannabis sativa extracts for anti-tick activities against Rhipicephalus (Boophilus) microplus
Naughton_2020_Toxicology__152379Multifunctional compounds Lithium Chloride and Methylene Blue attenuate the negative effects of diisopropylfluorophosphate on axonal transport in rat cortical neurons
Naujock_2020_Stem.Cells.Dev_29_1577Neuronal Differentiation of Induced Pluripotent Stem Cells from Schizophrenia Patients in Two-Dimensional and in Three-Dimensional Cultures Reveals Increased Expression of the Kv4.2 Subunit DPP6 That Contributes to Decreased Neuronal Activity
Nayak_2020_3.Biotech_10_476Anti-snake venom and methanolic extract of Andrographis paniculata: a multipronged strategy to neutralize Naja naja venom acetylcholinesterase and hyaluronidase
Nayak_2020_Cell.Rep_30_672Adaptive Thermogenesis in Mice Is Enhanced by Opsin 3-Dependent Adipocyte Light Sensing
Nazeeh_2020_Data.Brief_31_105980Summary data of home proximity to the nearest greenhouse (floricultural) crops and areas of greenhouse crops around various distances from homes in agricultural settings in Ecuador
Nazir_2020_BMC.Complement.Med.Ther_20_143Evaluation of neuroprotective and anti-amnesic effects of Elaeagnus umbellata Thunb. On scopolamine-induced memory impairment in mice
Nepovimova_2020_Bioorg.Chem_107_104596Tacrine - Benzothiazoles: Novel class of potential multitarget anti-Alzheimes drugs dealing with cholinergic, amyloid and mitochondrial systems
Neto_2020_J.Toxicol.Environ.Health.A__1Glyphosate-based herbicide impairs energy metabolism and increases autophagy in C6 astroglioma cell line
Ng_2020_Nat.Prod.Res__1Immuno-modulatory effects of macluraxanthone on macrophage phenotype and function
Ngoupaye_2020_Biomed.Pharmacother_130_110603Antidepressant and anti-amnesic effects of the aqueous lyophilisate of the leaves of Leptadenia arborea on an animal model of cognitive deficit associated depression
Nguyen_2020_Cell.Rep_33_108316Lysosomal Acid Lipase Is Required for Donor T Cells to Induce Graft-versus-Host Disease
Nguyen_2020_Food.Chem_318_126482Interactions between trans-resveratrol and CpLIP2 lipase/acyltransferase: Evidenced by fluorescence and in silico
Nguyen_2020_Front.Synaptic.Neurosci_12_33Neuroligins and Neurodevelopmental Disorders: X-Linked Genetics
Nguyen_2020_Molecules_25_Exploring Aurone Derivatives as Potential Human Pancreatic Lipase Inhibitors through Molecular Docking and Molecular Dynamics Simulations
Nguyen_2020_Neuron_106_759A Cluster of Autism-Associated Variants on X-Linked NLGN4X Functionally Resemble NLGN4Y
Nguyen_2020_Polymers.(Basel)_12_Microbial Reclamation of Chitin and Protein-Containing Marine By-Products for the Production of Prodigiosin and the Evaluation of Its Bioactivities
Nho_2020_J.Microbiol.Biotechnol_30_359Neuroprotective Effects of Phlorotannin-Rich Extract from Brown Seaweed Ecklonia cava on Neuronal PC-12 and SH-SY5Y Cells with Oxidative Stress
Niazi_2020_Cureus_12_e9849Rare Case of Iatrogenic Myocardial Infarction Induced by Use of Pyridostigmine
Nicolai_2020_Pharmaceuticals.(Basel)_13_Assessment of the Potential Skin Application of Plectranthus ecklonii Benth
Niendorf_2020_Acta.Physiol.(Oxf)_228_e13392Google maps for tissues: Multiscale imaging of biological systems and disease
Nifli_2020_Front.Pharmacol_11_618344Editorial: Cognitive Impairment: Therapy Momentum in the Continuum of Life
Nikbin_2020_Environ.Toxicol__Aerobic exercise and eugenol supplementation ameliorated liver injury induced by chlorpyrifos via modulation acetylcholinesterase activation and antioxidant defense
Niu_2020_Medicine.(Baltimore)_99_e19527Prophylactic cognitive enhancers for improvement of cognitive function in patients undergoing electroconvulsive therapy: A systematic review and meta-analysis
Nizam_2020_Clin.Case.Rep_8_905Lipase hypersecretion syndrome: A rare cutaneous manifestation of advanced pancreatic acinar cell carcinoma
Nizami_2020_J.Family.Med.Prim.Care_9_2521Intramuscular pyrethroid with organophosphorus (cypermethrine 3% + quinolphos 20%) mixed poisoning, its clinical presentation and management
Niznik_2020_Alzheimers.Dement__Impact of deprescribing AChEIs on aggressive behaviors and antipsychotic prescribing
Niznik_2020_J.Am.Geriatr.Soc_68_2412Reply to: Acetylcholinesterase Inhibitors and Dementia: Over Both Sides of the Atlantic Ocean
Niznik_2020_J.Am.Geriatr.Soc_68_699Risk for Health Events After Deprescribing Acetylcholinesterase Inhibitors in Nursing Home Residents With Severe Dementia
Njan_2020_Heliyon_6_e03514Subchronic exposure to Kafura; its neurotoxic potentials in young adult female Wistar rats
Njan_2020_Heliyon_6_e04011Neuroprotective and memory-enhancing effects of methanolic leaf extract of Peristrophe bicalyculata in rat model of type 2 diabetes mellitus
Nkoom_2020_Ecotoxicol.Environ.Saf_205_111106Biological uptake, depuration and biochemical effects of diclofenac and carbamazepine in Carassius carassius
Nkpaa_2020_J.Biochem.Mol.Toxicol__e22681Ethanol exacerbates manganese-induced oxidative/nitrosative stress, pro-inflammatory cytokines, nuclear factor-kappaB activation, and apoptosis induction in rat cerebellar cortex
Noby_2020_Anal.Biochem_591_113554Recombinant cold -adapted halotolerant, organic solvent-stable esterase (estHIJ) from Bacillus halodurans
Noda-Garcia_2020_Curr.Opin.Chem.Biol_59_147Enzyme evolution in natural products biosynthesis: target- or diversity-oriented?
Noda_2020_J.Stroke.Cerebrovasc.Dis__104882Mesial Frontal Lobe Infarction Presenting as Pisa Syndrome
Nogueira_2020_Environ.Toxicol.Pharmacol__103505Effects of low levels of the antibiotic ciprofloxacin on the polychaete Hediste diversicolor: biochemical and behavioural effects
Nomura_2020_Sci.Rep_10_15834Mechanism of central hypopnoea induced by organic phosphorus poisoning
Noriega_2020_Front.Physiol_11_588450Transcriptome Analysis and Knockdown of the Juvenile Hormone Esterase Gene Reveal Abnormal Feeding Behavior in the Sugarcane Giant Borer
Noronha-Matos_2020_J.Neurochem__e14975Nicotinic alpha7 receptor-induced adenosine release from perisynaptic Schwann cells controls acetylcholine spillover from motor endplates
Noschang_2020_Int.J.Dev.Neurosci_80_547Early-life stress affects behavioral and neurochemical parameters differently in male and female juvenile Wistar rats
Noshadi_2020_Chem.Biodivers_17_e2000197Synthesis, Characterization, Molecular Docking, and Biological Activities of Some Natural and Synthetic Urolithin Analogs
Noshita_2020_Bioorg.Med.Chem.Lett__127674Synthesis and biological activity of (+/-)-7,3',4'-trihydroxyhomoisoflavan and its analogs
Nowakowski_2020_Phytother.Res__The two faces of Coprinus comatus-Functional properties and potential hazards
Nunes_2020_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__108722Toxic effects of environmentally realistic concentrations of diclofenac in organisms from two distinct trophic levels, Hediste diversicolor and Solea senegalensis
Nunes_2020_Neuropharmacol__108089Examining the role of muscarinic M5 receptors in VTA cholinergic modulation of depressive-like and anxiety-related behaviors in rats
Nunez-Borque_2020_Mol.Neurobiol__Targeting Cannabinoid Receptor Activation and BACE-1 Activity Counteracts TgAPP Mice Memory Impairment and Alzheimer's Disease Lymphoblast Alterations
Nunez-Montero_2020_Biomolecules_10_673Genomic and Metabolomic Analysis of Antarctic Bacteria Revealed Culture and Elicitation Conditions for the Production of Antimicrobial Compounds
Nurfazilah_2020_Steroids__108735Medroxyprogesterone derivatives from microbial transformation as anti-proliferative agents and acetylcholineterase inhibitors (combined in vitro and in silico approaches)
Nuthakki_2020_Bioorg.Chem_107_104568Identification of aplysinopsin as a blood-brain barrier permeable scaffold for anti-cholinesterase and anti-BACE-1 activity
Nuylert_2020_Chembiochem_21_181Stabilization of Hydroxynitrile Lyases from Two Variants of Passion Fruit, Passiflora edulis Sims and Passiflora edulis Forma flavicarpa, by C-Terminal Truncation
Nuzzi_2020_Am.J.Alzheimers.Dis.Other.Demen_35_1533317520951693The Pupil Diameter as a Possible Indicator of Neurodegenerative Diseases and Response to Acetylcholinesterase Inhibitors Therapy: In-Depth Measurements Following Topical Administration of Tropicamide and Pilocarpine
Nwanna_2020_J.Food.Biochem__e13427Editan (Lasianthera africana) leaf-inclusive diets modulate some neuronal enzyme activities and antioxidant status of cyclophosphamide-treated Wistar rats
O'Brien_2020_BMC.Neurosci_21_43Neurologic effects of short-term treatment with a soluble epoxide hydrolase inhibitor after cardiac arrest in pediatric swine
O'Donovan_2020_Sci.Total.Environ_733_139102Effects of the UV filter, oxybenzone, adsorbed to microplastics in the clam Scrobicularia plana
Obafemi_2020_J.Diabetes.Metab.Disord_19_499Metformin/Donepezil combination modulates brain antioxidant status and hippocampal endoplasmic reticulum stress in type 2 diabetic rats
Oberleitner_2020_Chemosphere_261_127706Seasonal performance assessment of four riverbank filtration sites by combined non-target and effect-directed analysis
Oboh_2020_Neurotoxicol_77_12Rutin restores neurobehavioral deficits via alterations in cadmium bioavailability in the brain of rats exposed to cadmium
Oddsson_2020_Molecules_25_Structure-Based Discovery of Dual-Target Hits for Acetylcholinesterase and the alpha7 Nicotinic Acetylcholine Receptors: In Silico Studies and In Vitro Confirmation
Ogasawara_2020_J.Oleo.Sci_69_825Enzymatic Preparation and Oxidative Stability of Human Milk Fat Substitute Containing Polyunsaturated Fatty Acid Located at sn-2 Position
Ogata_2020_Chem.Pharm.Bull.(Tokyo)_68_1193Inhibition of Acetylcholinesterase by Wood Creosote and Simple Phenolic Compounds
Ogungbemi_2020_Neurotoxicol.Teratol__106918Optimization of the spontaneous tail coiling test for fast assessment of neurotoxic effects in the zebrafish embryo using an automated workflow in KNIME
Ogunsuyi_2020_J.Basic.Clin.Physiol.Pharmacol__Solanum leaves extracts exhibit antioxidant properties and inhibit monoamine oxidase and acetylcholinesterase activities (in vitro) in Drosophila melanogaster
Ogunsuyi_2020_J.Food.Biochem__e13150Solanum vegetable-based diets improve impairments in memory, redox imbalance, and altered critical enzyme activities in Drosophila melanogaster model of neurodegeneration
Ogunwale_2020_J.Bone.Miner.Res_35_440Acetylcholinesterase Inhibitors Are Associated with Reduced Fracture Risk among Older Veterans with Dementia
Oguz_2020_J.Enzyme.Inhib.Med.Chem_35_1215Synthesis of calix[4]azacrown substituted sulphonamides with antioxidant, acetylcholinesterase, butyrylcholinesterase, tyrosinase and carbonic anhydrase inhibitory action
Oh_2020_Am.J.Chin.Med__1Vaccinium bracteatum Improves Spatial Learning and Memory by Regulating N-methyl-D-aspartate Receptors and Tau Phosphorylation in Chronic Restraint Stress-Induced Memory Impaired Mice
Oh_2020_Antioxidants.(Basel)_10_Memory-Enhancing Effects of Mangosteen Pericarp Water Extract through Antioxidative Neuroprotection and Anti-Apoptotic Action
Oh_2020_Molecules_25_Novel Class of Chalcone Oxime Ethers as Potent Monoamine Oxidase-B and Acetylcholinesterase Inhibitors
Ohara_2020_J.Clin.Med_9_Shear Wave Dispersion Predicts Liver Fibrosis and Adverse Outcomes in Patients with Heart Failure
Ohura_2020_Drug.Metab.Dispos_48_146Identification and Characterization of a New Carboxylesterase 2 Isozyme, mfCES2C, in the Small Intestine of Cynomolgus Monkeys
Ohura_2020_Yakugaku.Zasshi_140_369[Evaluation of the Oral Absorption of Ester-type Prodrugs]
Ojo_2020_J.Sci.Food.Agric__Gongronema latifolium Benth. leaf extract attenuates diabetes induced neuropathy via inhibition of cognitive, oxidative stress and inflammatory response
Okello_2020_Nutrients_12_Comparative Kinetics of Acetyl- and Butyryl-Cholinesterase Inhibition by Green Tea Catechins|Relevance to the Symptomatic Treatment of Alzheimer's Disease
Okesola_2020_J.Int.Med.Res_48_300060520922649Effect of Solanum macrocarpon Linn leaf aqueous extract on the brain of an alloxan-induced rat model of diabetes
Okoh_2020_Mol.Biol.Rep_47_7709D-Ribose-L-cysteine exhibits adaptogenic-like activity through inhibition of oxido-inflammatory responses and increased neuronal caspase-3 activity in mice exposed to unpredictable chronic mild stress
Okten_2020_Arch.Pharm.(Weinheim)__e2000086Quinoline-based promising anticancer and antibacterial agents, and some metabolic enzyme inhibitors
Oku_2020_Elife_9_Alternative splicing at neuroligin site A regulates glycan interaction and synaptogenic activity
Okubo Eneni_2020_Drug.Metab.Pers.Ther__Diosmin attenuates schizophrenia-like behavior, oxidative stress, and acetylcholinesterase activity in mice
Oladele_2020_Toxicol.Rep_7_1223Neuroprotective mechanism of Vernonia amygdalina in a rat model of neurodegenerative diseases
Olah_2020_Eur.J.Neurosci_52_3776Dissociating cholinergic influence on alertness and temporal attention in primates in a simple reaction time paradigm
Olajuyigbe_2020_Environ.Sci.Pollut.Res.Int__Bioremediation treatment improves water quality for Nile tilapia (Oreochromis niloticus) under crude oil pollution
Olasehinde_2020_BMC.Complement.Med.Ther_20_251Sulfated polysaccharides of some seaweeds exhibit neuroprotection via mitigation of oxidative stress, cholinergic dysfunction and inhibition of Zn - induced neuronal damage in HT-22 cells
Olasehinde_2020_J.Food.Biochem__e13395Cholinesterase inhibitory activity, antioxidant properties, and phytochemical composition of Chlorococcum sp. extracts
Olasehinde_2020_Nutr.Neurosci__1Beetroot supplemented diet exhibit anti-amnesic effect via modulation of cholinesterases, purinergic enzymes, monoamine oxidase and attenuation of redox imbalance in the brain of scopolamine treated male rats
Olisah_2020_Environ.Geochem.Health__Systematic mapping of organophosphate contaminant (OPC) research trends between 1990 and 2018
Olivares-Rubio_2020_Chemosphere_264_128401Acetylcholinesterase activity in fish species exposed to crude oil hydrocarbons: A review and new perspectives
Oliveira_2020_Arch.Physiol.Biochem__1Brazilian native fruit extracts act as preventive agents modulating the purinergic and cholinergic signalling in blood cells and serum in a rat model of metabolic syndrome
Oliveira_2020_Plant.Physiol.Biochem_156_49Feruloyl esterase activity and its role in regulating the feruloylation of maize cell walls
Oliveira_2020_Toxins.(Basel)_12_Chemical and Pharmacological Screening of Rhinella icterica (Spix 1824) Toad Parotoid Secretion in Avian Preparations
Ollerhead_2020_Environ.Pollut_260_114044Polyvinylpyrolidone-functionalized silver nanoparticles do not affect aerobic performance or fractional rates of protein synthesis in rainbow trout (Oncorhynchus mykiss)
Omidpanah_2020_Nat.Prod.Res__1Phytochemical investigation and anticholinesterase activity of ethyl acetate fraction of Myristica fragrans Houtt. seeds
Omoarelojie_2020_Plant.Physiol.Biochem_155_965Synthetic strigolactone (rac-GR24) alleviates the adverse effects of heat stress on seed germination and photosystem II function in lupine seedlings
Onaolapo_2020_Curr.Pharm.Biotechnol_21_158High Dietary Fat Modulates Neurobehavioural Effect of Lopinavir/ Ritonavir in Mice
Onaolapo_2020_Pharmacol.Rep_72_55Dietary zinc supplement militates against ketamine-induced behaviours by age-dependent modulation of oxidative stress and acetylcholinesterase activity in mice
Onder_2020_Arch.Biochem.Biophys__108728Inhibition of cholinesterases by safranin O: Integration of inhibition kinetics with molecular docking simulations
Ongnok_2020_Biochim.Biophys.Acta.Mol.Basis.Dis__165975Donepezil provides neuroprotective effects against brain injury and Alzheimer's pathology under conditions of cardiac ischemia/reperfusion injury
Oresanya_2020_J.Food.Biochem__e13137Isolation of flavonoids from Musa acuminata Colla (Simili radjah, ABB) and the in vitro inhibitory effects of its leaf and fruit fractions on free radicals, acetylcholinesterase, 15-lipoxygenase, and carbohydrate hydrolyzing enzymes
Orlovic_2020_Acta.Clin.Croat_59_771THE ENIGMA OF LEWY BODY DEMENTIA: A CASE REPORT
Ortner_2020_Drug.Des.Devel.Ther_14_3251Therapeutic Drug Monitoring of Rivastigmine and Donepezil Under Consideration of CYP2D6 Genotype-Dependent Metabolism of Donepezil
Ortner_2020_Front.Pharmacol_11_691Serum Concentrations of Cholinesterase Inhibitors in Patients With Alzheimer's Dementia Are Frequently Below the Recommended Levels
Oset-Gasque_2020_Curr.Med.Chem_27_4392Tacrine-Natural-Product Hybrids for Alzheimer's Disease Therapy
Osler_2020_Am.J.Psychiatry__appiajp201919030315Associations of Benzodiazepines, Z-Drugs, and Other Anxiolytics With Subsequent Dementia in Patients With Affective Disorders: A Nationwide Cohort and Nested Case-Control Study
Ostrowska_2020_Saudi.Pharm.J_28_220Coumarin-piperazine derivatives as biologically active compounds
Oszmianski_2020_Plants.(Basel)_9_Roots and Leaf Extracts of Dipsacus fullonum L. and Their Biological Activities
Otreba_2020_Eur.J.Pharmacol_887_173553Antiviral activity of chlorpromazine, fluphenazine, perphenazine, prochlorperazine, and thioridazine towards RNA-viruses. A review
Otreba_2020_Molecules_25_Cardioprotective Activity of Selected Polyphenols Based on Epithelial and Aortic Cell Lines. A Review
Ou_2020_Analyst__Novel turn on-off paper sensor based on nonionic conjugated polythiophene-coated CdTe QDs for efficient visual detection of cholinesterase activity
Oumbouke_2020_Sci.Rep_10_15066Fine scale spatial investigation of multiple insecticide resistance and underlying target-site and metabolic mechanisms in Anopheles gambiae in central Cte d'Ivoire
Ouyang_2020_BMC.Infect.Dis_20_952Temporal changes in laboratory markers of survivors and non-survivors of adult inpatients with COVID-19
Over_2020_Arh.Hig.Rada.Toksikol_71_211Oxidative and apoptotic effects of fluoxetine and its metabolite norfluoxetine in Daphnia magna
Overby_2020_Int.J.Mol.Sci_21_Soluble Epoxide Hydrolase Inhibition by t-TUCB Promotes Brown Adipogenesis and Reduces Serum Triglycerides in Diet-Induced Obesity
Oyagbemi_2020_Environ.Toxicol_35_242Clofibrate, a PPAR-alpha agonist, abrogates sodium fluoride-induced neuroinflammation, oxidative stress, and motor incoordination via modulation of GFAP/Iba-1/anti-calbindin signaling pathways
Oyedeji_2020_Pestic.Biochem.Physiol_168_104643Insecticidal and biochemical activity of essential oil from Citrus sinensis peel and constituents on Callosobrunchus maculatus and Sitophilus zeamais
Oyeleye_2020_J.Food.Biochem__e13323Moringa oleifera leaf and seed inclusive diets influenced the restoration of biochemicals associated with erectile dysfunction in the penile tissue of STZ-induced diabetic male rats treated with/without Acarbose drug
Oyeleye_2020_J.Food.Biochem__e13558Citrus spp. essential oils improve behavioral pattern, repressed cholinesterases and monoamine oxidase activities, and production of reactive species in fruit fly (Drosophila melanogaster) model of Alzheimer's Disease
Oyeniran_2020_J.Basic.Clin.Physiol.Pharmacol_32_987Phenolic constituents and inhibitory effects of the leaf of Rauvolfia vomitoria Afzel on free radicals, cholinergic and monoaminergic enzymes in rat's brain in vitro
Oyeniran_2020_J.Food.Biochem__e13401Comparative study of the phenolic profile, antioxidant properties, and inhibitory effects of Moringa (Moringa oleifera Lam.) and Almond (Terminalia catappa Linn.) leaves on acetylcholinesterase and monoamine oxidase activities in the head region of Fruitfly (Drosophila melanogaster Meigen) in vitro
Ozcan_2020_Saudi.Pharm.J_28_95Antibacterial, antioxidant and enzyme inhibition activity capacities of Doronicum macrolepis (FREYN&SINT): An endemic plant from Turkey
Ozenil_2020_Eur.J.Med.Chem_204_112623Enhanced arecoline derivatives as muscarinic acetylcholine receptor M1 ligands for potential application as PET radiotracers
Ozer_2020_Appl.Biochem.Biotechnol_190_721Use of Feruloyl Esterase as Laccase-Mediator System in Paper Bleaching
Ozgen_2020_Turk.J.Pharm.Sci_17_528Cholinesterase and Tyrosinase Inhibitory Potential and Antioxidant Capacity of Lysimachia verticillaris L. and Isolation of the Major Compounds
Oztug_2020_OMICS_24_756Thermal Proteome Profiling and Meltome Analysis of a Thermophilic Bacterial Strain, Geobacillus thermoleovorans ARTRW1: Toward Industrial Applications
Ozyilmaz_2020_Bioprocess.Biosyst.Eng_43_2085Effect of cyclic and acyclic surfactants on the activity of Candida rugosa lipase
Pachon_2020_Int.J.Mol.Sci_21_Synthesis of Hantzsch Adducts as Cholinesterases and Calcium Flux inhibitors, Antioxidants and Neuroprotectives
Padhi_2020_Biochem.Biophys.Res.Commun_532_528Characterization of the rat Acetylcholinesterase readthrough (AChE-R) splice variant: Implications for toxicological studies
Padrtova_2020_Curr.Org.Synth_17_576Indol-2-Carboxylic Acid Esters Containing N-Phenylpiperazine Moiety - Preparation and Cholinesterase-inhibiting Activity
Paez-Perez_2020_ACS.Omega_5_25841Bioinformatic Analysis and Biophysical Characterization Reveal Structural Disorder in G0S2 Protein
Paganotto_2020_Environ.Pollut_268_115783Behavioral changes occur earlier than redox alterations in developing zebrafish exposed to Mancozeb
Paine_2020_Drug.Metab.Dispos_48_956Natural Products: Experimental Approaches to Elucidate Disposition Mechanisms and Predict Pharmacokinetic Drug Interactions
Pajk_2020_J.Enzyme.Inhib.Med.Chem_35_498Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probes
Palakkathondi_2020_ACS.Comb.Sci_22_592(Hetero-)(arylidene)arylhydrazides as Multitarget-Directed Monoamine Oxidase Inhibitors
Palevich_2020_Genome.Biol.Evol_12_1566Complete Genome Sequence of the Polysaccharide-Degrading Rumen Bacterium Pseudobutyrivibrio xylanivorans MA3014 Reveals an Incomplete Glycolytic Pathway
Pallares_2020_Conserv.Physiol_8_coaa067Beyond survival experiments: using biomarkers of oxidative stress and neurotoxicity to assess vulnerability of subterranean fauna to climate change
Pallas_2020_Biomolecules_10_Soluble Epoxide Hydrolase Inhibition to Face Neuroinflammation in Parkinson's Disease: A New Therapeutic Strategy
Palomaki_2020_Genet.Med_22_462Laboratory screening and diagnosis of open neural tube defects, 2019 revision: a technical standard of the American College of Medical Genetics and Genomics (ACMG)
Pamio_2020_Psychogeriatrics__Are cytochrome P4502D6 and apolipoprotein E genotypes associated with long-term cognitive and functional changes in patients treated with donepezil?
Panda_2020_Curr.Med.Chem_27_5887Natural Products as Potential Anti-Alzheimer Agents
Panda_2020_J.Cell.Physiol_235_2776Deacetylation of LAMP1 drives lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer
Pandey_2020_BMC.Complement.Med.Ther_20_198Bergenia pacumbis from Nepal, an astonishing enzymes inhibitor
Pandey_2020_Curr.Comput.Aided.Drug.Des_16_54De-novo Drug Design, Molecular Docking and In-Silico Molecular Prediction of AChEI Analogues through CADD Approaches as Anti-Alzheimer's Agents
Pandey_2020_Exp.Gerontol__111010Swertiamarin, a secoiridoid glycoside modulates nAChR and AChE activity
Pandey_2020_Psychopharmacology.(Berl)__7,8-Dihydroxyflavone alleviated the high-fat diet and alcohol-induced memory impairment: behavioral, biochemical and molecular evidence
Pang_2020_Bioorg.Chem_107_104600Structurally various sorbicillinoids from the deep-sea sediment derived fungus Penicillium sp. SCSIO06871
Pang_2020_Surg.Laparosc.Endosc.Percutan.Tech__Surgical Choice for Different Types of Gallbladder Adenomyomatosis: An Initial Experience of 20 Years Laparoscopic Cholecystectomy
Panghal_2020_Heliyon_6_e03431Gallic acid and MiADMSA reversed arsenic induced oxidative/nitrosative damage in rat red blood cells
Panigrahy_2020_Cancer.Metastasis.Rev__Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19?
Pankin_2020_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_246_118979Laser-induced twisting of phosphorus functionalized thiazolotriazole as a way of cholinesterase activity change
Pantaleao_2020_Curr.Top.Med.Chem_20_209Integrated Protocol to Design Potential Inhibitors of Dipeptidyl Peptidase- 4 (DPP-4)
Pantoja-Pulido_2020_Insects_11_Insecticidal and Cholinesterase Activity of Dichloromethane Extracts of Tithonia diversifolia on Atta cephalotes Worker Ants (Formicidae: Myrmicinae)
Pape_2020_Cancers.(Basel)_12_Efficacy and Safety of CAP7.1 as Second-Line Treatment for Advanced Biliary Tract Cancers: Data from a Randomised Phase II Study
Papke_2020_Curr.Top.Behav.Neurosci_45_123Cholinergic Receptors and Addiction
Paradhipta_2020_Microorganisms_8_Dual-Purpose Inoculants and Their Effects on Corn Silage
Paraiso-Luna_2020_Development_147_Endocannabinoid signalling in stem cells and cerebral organoids drives differentiation to deep layer projection neurons via CB(1) receptors
Parelho_2020_Chemosphere__128601Bioaccumulation and potential ecotoxicological effects of trace metals along a management intensity gradient in volcanic pasturelands
Park_2020_Ann.Dermatol_32_473pH-Dependent Expression, Stability, and Activity of Malassezia restricta MrLip5 Lipase
Park_2020_Ecotoxicol.Environ.Saf_208_111452Biomonitoring the effects of urban-stream waters on the health status of pale chub (Zacco platypus): A comparative analysis of biological indexes and biomarker levels
Park_2020_Int.J.Biol.Macromol_164_4650Characterization of a novel carboxylesterase belonging to family VIII hydrolyzing beta-lactam antibiotics from a compost metagenomic library
Park_2020_Int.J.Mol.Sci_21_Human Neural Stem Cells Encoding ChAT Gene Restore Cognitive Function via Acetylcholine Synthesis, Abeta Elimination, and Neuroregeneration in APPswe/PS1dE9 Mice
Park_2020_Molecules_25_Bioassay-Guided Isolation of Anti-Alzheimer Active Components from the Aerial Parts of Hedyotis diffusa and Simultaneous Analysis for Marker Compounds
Parmeggiani_2020_Res.Vet.Sci_132_54Initial ontogeny of digestive enzymes in the early life stages of captive-bred European eels during fasting: A partial characterization
Pasangulapati_2020_Adv.Exp.Med.Biol_1195_213Ocimum Sanctum Linn: A Potential Adjunct Therapy for Hyperhomocysteinemia-Induced Vascular Dementia
Pascual_2020_Curr.Opin.Chem.Biol_61_9Carbohydrate de-N-acetylases acting on structural polysaccharides and glycoconjugates
Patel_2020_ACS.Chem.Neurosci_11_3557Further Studies on Triazinoindoles as Potential Novel Multitarget-Directed Anti-Alzheimer's Agents
Patel_2020_Bioorg.Chem_101_103977Novel carbazole-stilbene hybrids as multifunctional anti-Alzheimer agents
Pathirage_2020_Parasit.Vectors_13_246Insecticide susceptibility of the sand fly leishmaniasis vector Phlebotomus argentipes in Sri Lanka
Patil_2020_J.Am.Coll.Nutr__1Multidimensional Studies of Pancratium parvum Dalzell Against Acetylcholinesterase: A Potential Enzyme for Alzheimer's Management
Patinios_2020_Front.Microbiol_11_579844Eat1-Like Alcohol Acyl Transferases From Yeasts Have High Alcoholysis and Thiolysis Activity
Patwa_2020_Metallomics_12_1428Monoisoamyl DMSA reduced copper-induced neurotoxicity by lowering 8-OHdG level, amyloid beta and Tau protein expressions in Sprague-Dawley rats
Paudel_2020_Drug.Discov.Ther__A systematic review on anti-Alzheimer's disease activity of prescription Kangen-karyu
Paul_2020_Environ.Pollut_260_114001A multi-biomarker approach using integrated biomarker response to assess the effect of pH on triclosan toxicity in Pangasianodon hypophthalmus (Sauvage, 1878)
Paventi_2020_Biomolecules_10_Biological Activity of Humulus Lupulus (L.) Essential Oil and Its Main Components Against Sitophilus granarius (L.)
Pavlic_2020_Food.Chem_338_127724Antioxidant and enzyme-inhibitory activity of peppermint extracts and essential oils obtained by conventional and emerging extraction techniques
Pavlov_2020_Int.J.Pharm__119640Biomedical potentialities of cationic geminis as modulating agents of liposome in drug delivery across biological barriers and cellular uptake
Payrits_2020_Mech.Ageing.Dev__111268Genetic deletion of trpa1 receptor attenuates amyloid beta- 1-42 (abeta1-42)-induced neurotoxicity in the mouse basal forebrain in vivo
Pearson-Smith_2020_Neurobiol.Dis_133_104457Antioxidant drug therapy as a neuroprotective countermeasure of nerve agent toxicity
Pedroso_2020_Mar.Environ.Res__105221A toxicological comparison between two uranium compounds in Artemia salina: Artificial seawater containing CaCO(3)
Pei_2020_Mol.Cell.Biochem_475_107LncRNA KCNQ1OT1 ameliorates the liver injury induced by acetaminophen through the regulation of miR-122-5p/CES2 axis
Peixoto_2020_Nat.Prod.Res__1Kopsanone and N-oxide isolated from Aspidosperma macrocarpon Mart. (Apocynaceae) leaves and their MAO-A inhibitory activity
Peng_2020_Food.Chem_313_126130Trace water activity could improve the formation of 1,3-oleic-2-medium chain-rich triacylglycerols by promoting acyl migration in the lipase RM IM catalyzed interesterification
Peng_2020_Reprod.Sci_27_233Downregulated ABHD5 Aggravates Insulin Resistance of Trophoblast Cells During Gestational Diabetes Mellitus
Pengsook_2020_Nat.Prod.Res__1Insecticidal activity of isolated phenylpropanoids from Alpinia galanga rhizomes against Spodoptera litura
Peretti_2020_Acta.Histochem_122_151598Short-term effects of whole-body vibration on the soleus of ooforectomized rats: Histomorphometric analysis and oxidative stress in an animal model
Perez-Areales_2020_J.Med.Chem_63_9360Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6
Perez-Calabuig_2020_Chem.Commun.(Camb)__An enzyme-controlled Janus nanomachine for on-command dual and sequential release
Perez-Fernandez_2020_Exp.Neurol__113356Postnatal exposure to low doses of Chlorpyrifos induces long-term effects on 5C-SRTT learning and performance, cholinergic and GABAergic systems and BDNF expression
Perez-Iglesias_2020_Environ.Sci.Pollut.Res.Int_27_2131An imazethapyr-based herbicide formulation induces genotoxic, biochemical, and individual organizational effects in Leptodactylus latinasus tadpoles (Anura: Leptodactylidae)
Perin_2020_Arch.Insect.Biochem.Physiol__e21731Jaburetox, a urease-derived peptide: Effects on enzymatic pathways of the cockroach Nauphoeta cinerea
Perinova_2020_Bioorg.Chem_100_103928Functionalized aromatic esters of the Amaryllidaceae alkaloid haemanthamine and their in vitro and in silico biological activity connected to Alzheimer's disease
Peris-Sampedro_2020_Behav.Brain.Res_384_112552Improvement of APOE4-dependent non-cognitive behavioural traits by postnatal cholinergic stimulation in female mice
Pervaiz_2020_Chem.Biodivers__Organocatalyzed solvent free and efficient synthesis of 2,4,5-trisubstituted imidazoles as potential acetylcholinesterase inhibitors for Alzheimer's disease
Pervaiz_2020_Food.Res.Int_137_109606Multidirectional insights into the phytochemical, biological, and multivariate analysis of the famine food plant (Calligonum polygonoides L).: A novel source of bioactive phytocompounds
Petan_2020_Rev.Physiol.Biochem.Pharmacol__Lipid Droplets in Cancer
Petrazzuoli_2020_Scand.J.Prim.Health.Care__1Unburdening dementia a basic social process grounded theory - based on a primary care physician survey from 25 countries
Petrenko_2020_Crystallogr.Rep_65_264Screening of Conditions that Facilitate Crystallization of Oligopeptidase B from Serratia Proteamaculans by Differential Scanning Fluorimetry
Petrenko_2020_Crystallogr.Rep_65_909Crystallographic Study of Mutants and Complexes of Oligopeptidase B from Serratia proteamaculans
Petrenko_2020_J.Biomol.Struct.Dyn_38_4868Molecular dynamics complemented by site-directed mutagenesis reveals significant difference between the interdomain salt bridge networks stabilizing oligopeptidases B from bacteria and protozoa in their active conformations
Petreski_2020_Arh.Hig.Rada.Toksikol_71_163Cholinergic syndrome: a case report of acute organophosphate and carbamate poisoning
Petry_2020_Food.Res.Int_137_109691Addition of either gastric lipase or cholesterol esterase to improve both beta-cryptoxanthin ester hydrolysis and micellarization during in vitro digestion of fruit pulps
Pfitzinger_2020_J.Exp.Clin.Cancer.Res_39_289Indirect cholinergic activation slows down pancreatic cancer growth and tumor-associated inflammation
Pham_2020_J.Biol.Chem__Structural insights into the putative bacterial acetylcholinesterase ChoE and its substrate inhibition mechanism
Phua_2020_BMJ.Neurol.Open_2_e000028Myasthenia gravis and concurrent myositis following PD-L1 checkpoint inhibitor for non-small cell lung cancer
Phyu_2020_Med.Hypotheses_144_110186A potential therapeutic combination for treatment of COVID-19: Synergistic effect of DPP4 and RAAS suppression
Piamonte_2020_J.Alzheimers.Dis_76_725Effects of Citicoline as an Adjunct Treatment for Alzheimer's Disease: A Systematic Review
Piccoli_2020_Environ.Sci.Pollut.Res.Int_27_4799High level of methylmercury exposure causes persisted toxicity in Nauphoeta cinerea
Piemontese_2020_Molecules_25_Deep Eutectic Solvents as Effective Reaction Media for the Synthesis of 2-Hydroxyphenylbenzimidazole-based Scaffolds en Route to Donepezil-Like Compounds
Pinteus_2020_Sci.Total.Environ_750_141372The marine invasive seaweeds Asparagopsis armata and Sargassum muticum as targets for greener antifouling solutions
Piras_2020_Nat.Prod.Res__1Supercritical extraction of volatile and fixed oils from Petroselinum crispum L. seeds: chemical composition and biological activity
Pires_2020_Pestic.Biochem.Physiol_163_14Differential effects of azinphos-methyl and chlorpyrifos on polyamine oxidative metabolism during the embryonic development of Rhinella arenarum and its relation to oxidative stress
Pirone_2020_J.Chem.Neuroanat__101843Immunolocalization of cannabinoid receptor 1 (CB1), monoglyceride lipase (MGL) and fatty-acid amide hydrolase 1 (FAAH) in the pig claustrum
Pitchai_2020_Heliyon_6_e04930Molecular interaction of human acetylcholinesterase with trans-tephrostachin and derivatives for Alzheimer's disease
Pizent_2020_Biomolecules_10_Cigarette Smoking during Pregnancy: Effects on Antioxidant Enzymes, Metallothionein and Trace Elements in Mother-Newborn Pairs
Placines_2020_Plants.(Basel)_9_Phenolic Profile, Toxicity, Enzyme Inhibition, In Silico Studies, and Antioxidant Properties of Cakile maritima Scop. (Brassicaceae) from Southern Portugal
Plaks_2020_Biochemistry_59_3993Rosetta-Enabled Structural Prediction of Permissive Loop Insertion Sites in Proteins
Platsaki_2020_J.Biol.Chem_295_16267The Ig-like domain of Punctin/MADD-4 is the primary determinant for interaction with the ectodomain of neuroligin NLG-1
Plomp_2020_Environ.Toxicol.Chem_39_1988The Single and Combined Effects of Wildfire Runoff and Sediment-Bound Copper on the Freshwater Amphipod Hyalella azteca
Poeschl_2020_ACS.Omega_5_2378Synthetic Approaches for Piperidone-Based Templates as Scaffolds to Access Chirally Enriched Donepezil Analogues
Pohanka_2020_Curr.Med.Chem_27_2994Diagnoses of Pathological States Based on Acetylcholinesterase and Butyrylcholinesterase
Pohanka_2020_Mini.Rev.Med.Chem_20_1532Inhibitors of Cholinesterases in Pharmacology: the Current Trends
Poirier_2020_Sci.Rep_10_3843Enzymatic decontamination of paraoxon-ethyl limits long-term effects in planarians
Polli_2020_Nat.Prod.Res__1Secondary metabolites of Curvularia sp. G6-32, an endophyte of Sapindus saponaria, with antioxidant and anticholinesterasic properties
Ponne_2020_Metab.Brain.Dis_35_503Verapamil attenuates scopolamine induced cognitive deficits by averting oxidative stress and mitochondrial injury - A potential therapeutic agent for Alzheimer's Disease
Poopal_2020_Chemosphere_252_126498Biochemical and behavior effects induced by diheptyl phthalate (DHpP) and Diisodecyl phthalate (DIDP) exposed to zebrafish
Potasiewicz_2020_Behav.Brain.Res__112547Positive allosteric modulators of alpha 7 nicotinic acetylcholine receptors enhance procognitive effects of conventional anti-Alzheimer drugs in scopolamine-treated rats
Potshangbam_2020_J.Biomol.Struct.Dyn__1An in silico approach to identify potential medicinal plants for treating Alzheimer disease: a case study with acetylcholinesterase
Poursharifi_2020_JCI.Insight_5_Adipose ABHD6 regulates tolerance to cold and thermogenic programs
Powell_2020_Expert.Rev.Neurother__1Treating hallucinations in Parkinson's disease
Prabhakar_2020_Ann.Indian.Acad.Neurol_23_767Efficacy of Bacopa Monnieri (Brahmi) and Donepezil in Alzheimer's Disease and Mild Cognitive Impairment: A Randomized Double-Blind Parallel Phase 2b Study
Prasannaraja_2020_Prep.Biochem.Biotechnol__1A dipyrrole derivative from Aloe vera inhibits an anti-diabetic drug target Dipeptidyl Peptidase (DPP)-IV in vitro
Prattipati_2020_Enzyme.Microb.Technol_140_109633Pichia pastoris Protein Disulfide Isomerase (PDI1) promoter for heterologous protein production and its sequence characterization
Pravisani_2020_Hepatobiliary.Surg.Nutr_9_183Is there any correlation between liver graft regeneration and recipient's pretransplant skeletal muscle mass?-a study in extended left lobe graft living-donor liver transplantation
Prendecki_2020_Curr.Alzheimer.Res__Genetic Editing and Pharmacogenetics in Current And Future Therapy Of Neurocognitive Disorders
Price_2020_Biochemistry__Humanin blocks aggregation of amyloid beta induced by acetylcholinesterase, an effect abolished in the presence of IGFBP-3
Price_2020_Sci.Rep_10_5083IGFBP-3 Blocks Hyaluronan-CD44 Signaling, Leading to Increased Acetylcholinesterase Levels in A549 Cell Media and Apoptosis in a p53-Dependent Manner
Price_2020_Xenobiotica__1Kinetics of metabolism of deltamethrin and cis- and trans-permethrin in vitro. Studies using rat and human liver microsomes, isolated rat hepatocytes and rat liver cytosol
Prummer_2020_J.Vet.Intern.Med_34_2319Hyperlipasemia in critically ill dogs with and without acute pancreatitis: Prevalence, underlying diseases, predictors, and outcome
Prust_2020_Part.Fibre.Toxicol_17_24The plastic brain: neurotoxicity of micro- and nanoplastics
Pruszynska-Oszmalek_2020_Gen.Comp.Endocrinol__113615Short-term administration of spexin in rats reduces obesity by affecting lipolysis and lipogenesis: An in vivo and in vitro study
Przybylowska_2020_Med.Chem_16_947Synthesis and Cholinesterase Inhibitory Activity of N-Phosphorylated/ N-Tiophosphorylated Tacrine
Pu_2020_Proc.Natl.Acad.Sci.U.S.A__Maternal glyphosate exposure causes autism-like behaviors in offspring through increased expression of soluble epoxide hydrolase
Puchl'ova_2020_Molecules_25_Scalable Green Approach Toward Fragrant Acetates
Pulido_2020_Int.J.Mol.Sci_21_Functional Heterologous Expression of Mature Lipase LipA from Pseudomonas aeruginosa PSA01 in Escherichia coli SHuffle and BL21 (DE3): Effect of the Expression Host on Thermal Stability and Solvent Tolerance of the Enzyme Produced
Pullaguri_2020_Chemosphere__128930Triclosan affects motor function in zebrafish larva by inhibiting ache and syn2a genes
Purgatorio_2020_ChemMedChem_15_1947Scouting around 1,2,3,4-Tetrahydrochromeno[3,2-c]pyridin-10-ones for Single- and Multi-target Ligands Directed towards Relevant Alzheimer's Targets
Putra_2020_Ann.N.Y.Acad.Sci__Diapocynin, an NADPH oxidase inhibitor, counteracts diisopropylfluorophosphate-induced long-term neurotoxicity in the rat model
Pwint_2020_J.ASEAN.Fed.Endocr.Soc_35_85Correlation Study Between Erythrocyte Acetylcholinesterase Activity, Serum Malondialdehyde and Insulin Sensitivity in Agricultural Workers and Non-agricultural Workers in Nat-Kan Village, Magway Township
Qi_2020_Food.Chem_320_126683Detection of organophosphorus pesticides with liquid crystals supported on the surface deposited with polyoxometalate-based acetylcholinesterase-responsive supramolecular spheres
Qian_2020_Drug.Metab.Dispos_48_993Natural Products as Modulators of CES1 Activity
Qiao_2020_Sci.Total.Environ__143769Crosstalk of cholinergic pathway on thyroid disrupting effects of the insecticide chlorpyrifos in zebrafish (Danio rerio)
Qin_2020_Anal.Chim.Acta_1130_100Dissociable photoelectrode materials boost ultrasensitive photoelectrochemical detection of organophosphorus pesticides
Qin_2020_Bioorg.Chem__104519Polymethylated acylphloroglucinols from Rhodomyrtus tomentosa exert acetylcholinesterase inhibitory effects
Qing_2020_Mikrochim.Acta_187_497Thiol-suppressed I(2)-etching of AuNRs: acetylcholinesterase-mediated colorimetric detection of organophosphorus pesticides
Qiu_2020_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids__158663Carboxyl ester lipase is highly conserved in utilizing maternal supplied lipids during early development of zebrafish and human
Qiu_2020_Biotechnol.Adv__107607Microbial enzymes catalyzing keratin degradation: Classification, structure, function
Qiu_2020_Ecotoxicol.Environ.Saf_190_110148Identification and characterization of a novel phthalate-degrading hydrolase from a soil metagenomic library
Qiu_2020_Int.J.Biol.Macromol_164_1510Characterization of XtjR8: A novel esterase with phthalate-hydrolyzing activity from a metagenomic library of lotus pond sludge
Qiu_2020_Int.J.Endocrinol_2020_8874272DPP4 Activities Are Associated with Osteopenia/Osteoporosis and Fracture Risk in Newly Diagnosed Type 2 Diabetes
Qiu_2020_J.Basic.Microbiol_60_699Biodegradation of bis(2-hydroxyethyl) terephthalate by a newly isolated Enterobacter sp. HY1 and characterization of its esterase properties
Quan_2020_Am.J.Cancer.Res_10_1608MLL5alpha activates AR/NDRG1 signaling to suppress prostate cancer progression
Quitterer_2020_Pharmacol.Res_154_104230Improvements of symptoms of Alzheimer`s disease by inhibition of the angiotensin system
Rade_2020_Front.Bioeng.Biotechnol_8_304A Novel Fungal Lipase With Methanol Tolerance and Preference for Macaw Palm Oil
Radulovic_2020_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1865_158612Endothelial lipase increases eNOS activating capacity of high-density lipoprotein
Rahim_2020_J.Diet.Suppl__1Virgin Coconut Oil-Induced Neuroprotection in Lipopolysaccharide-Challenged Rats is Mediated, in Part, Through Cholinergic, Anti-Oxidative and Anti-Inflammatory Pathways
Rahimi_2020_Drug.Chem.Toxicol__1Adverse effects of textile dyes on antioxidant enzymes and cholinesterase activities in Drosophila melanogaster (Oregon R(+))
Rahimi_2020_Plant.Cell.Tissue.Organ.Cult__1Effect of photoperiod and plant growth regulators on in vitro mass bulblet proliferation of Narcissus tazzeta L. (Amaryllidaceae), a potential source of galantamine
Rahman_2020_Comput.Biol.Chem__107326Structure-based virtual screening of dipeptidyl peptidase 4 inhibitors and their in vitro analysis
Rahman_2020_Neuron_106_952Structure of the Native Muscle-type Nicotinic Receptor and Inhibition by Snake Venom Toxins
Rahman_2020_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_244_118803Spectroscopic and molecular modelling study of binding mechanism of bovine serum albumin with phosmet
Rajamohan_2020_J.Lipid.Res__Crystal Structure of human Lysosomal Acid Lipase and its Implications in Cholesteryl Ester Storage Disease (CESD)
Rajan_2020_Pharmacol.Res__104681Targeting Obesity with plant-derived pancreatic lipase inhibitors: A comprehensive review
Rajendran_2020_Biochemistry_59_183Functional Annotation of ABHD14B, an Orphan Serine Hydrolase Enzyme
Rajkumar_2020_Pestic.Biochem.Physiol_170_104679Development of encapsulated peppermint essential oil in chitosan nanoparticles: characterization and biological efficacy against stored-grain pest control
Ramesh_2020_Neurotoxicol.Teratol__106919Organophosphorus flame retardant induced hepatotoxicity and brain AChE inhibition on zebrafish (Danio rerio)
Ramires_2020_Environ.Pollut_260_113928Enzyme assays and toxicity of pig abattoir waste in Eisenia andrei
Ramirez-Santana_2020_Environ.Res_186_109539Association between cholinesterase's inhibition and cognitive impairment: A basis for prevention policies of environmental pollution by organophosphate and carbamate pesticides in Chile
Ramos_2020_Biomarkers__1Hypolipidemic and anti-inflammatory properties of phenolic rich Butia odorata fruit extract: potential involvement of paraoxonase activity
Rao_2020_Phytother.Res__A comprehensive review on ethnomedicine, phytochemistry, pharmacology, and toxicity of Tephrosia purpurea (L.) Pers
Rashedinia_2020_Biomed.Res.Int_2020_8297984Neuroprotective Effect of Syringic Acid by Modulation of Oxidative Stress and Mitochondrial Mass in Diabetic Rats
Rashid_2020_Cureus_12_e7425Review Analysis on Thymectomy vs Conservative Medical Management in Myasthenia Gravis
Rashu_2020_World.J.Clin.Cases_8_1642Cholesteryl ester storage disease of clinical and genetic characterisation: A case report and review of literature
Ratanachina_2020_Occup.Med.(Lond)_70_14Pesticide exposure and lung function: a systematic review and meta-analysis
Ravi_2020_J.Pharm.Pharmacol__Cassia tora extract alleviates Abeta1-42 aggregation processes in vitro and protects against aluminium-induced neurodegeneration in rats
Ray_2020_Transl.Psychiatry_10_47Rivastigmine modifies the alpha-secretase pathway and potentially early Alzheimer's disease
Rayamajhi_2020_Biotechnol.Bioprocess.Eng_25_414Functional Characterization of NgnL, an Alpha/beta-hydrolase Enzyme Involved in Biosynthesis of Acetylated Nodusmicin
Rea_2020_Int.J.Food.Sci.Nutr__1Hydroxycinnamic acid derivatives isolated from hempseed and their effects on central nervous system enzymes
Reale_2020_Int.J.Mol.Sci_21_Cholinergic Markers and Cytokines in OSA Patients
Recazens_2020_Prog.Lipid.Res__101084Hormone-sensitive lipase: sixty years later
Reddy_2020_Microorganisms_8_Polyphenols in Alzheimer's Disease and in the Gut-Brain Axis
Reddy_2020_Toxicol.Res_36_257Factors associated with outcomes in organophosphate and carbamate poisoning: a retrospective study
Reichert_2020_Sci.Rep_10_1658Common variation in FAM155A is associated with diverticulitis but not diverticulosis
Reichova_2020_Mol.Cell.Endocrinol__110924Abnormal neuronal morphology and altered synaptic proteins are restored by oxytocin in autism-related SHANK3 deficient model
Reis_2020_Braz.J.Otorhinolaryngol__Effects of subchronic inhalation exposure to an organophosphorus insecticide compound containing dichlorvos on wistar rats' otoacoustic emissions
Reis_2020_Mol.Neurobiol_57_5219Advances in the Understanding of Oxaliplatin-Induced Peripheral Neuropathy in Mice: 7-Chloro-4-(Phenylselanyl) Quinoline as a Promising Therapeutic Agent
Reis_2020_Nat.Prod.Res__1Acetylcholinesterase inhibitory activity of Ocotea pomaderroides extracts: HPLC-MS/MS characterization and molecular modeling studies
Ren_2020_Biomater.Sci_8_6533Increased cross-linking micelle retention in the brain of Alzheimer's disease mice by elevated asparagine endopeptidase protease responsive aggregation
Ren_2020_Bioorg.Chem_107_104599Discovery of Thai mangrove tetranortriterpenoids as agonists of human pregnane-X-receptor and inhibitors against human carboxylesterase 2
Ren_2020_Front.Pharmacol_11_571535A Review of the Pharmacological Properties of Psoralen
Ren_2020_Mol.Med.Rep_22_2063Expression levels of the alpha7 nicotinic acetylcholine receptor in the brains of patients with Alzheimer's disease and their effect on synaptic proteins in SH-SY5Y cells
Reyes-Chaparro_2020_Chem.Res.Toxicol_33_2765Human Biotransformation Pathway of Temephos Using an In Silico Approach
Reynolds_2020_Neurology__Association of out-of-pocket costs on adherence to common neurologic medications
Rial_2020_J.Chem.Ecol_46_871Phytochemical Study of Safflower Roots (Carthamus tinctorius) on the Induction of Parasitic Plant Germination and Weed Control
Riazi_2020_Br.J.Anaesth_125_859Perioperative genetic screening: entering a new era
Ribaudo_2020_ACS.Chem.Neurosci__Therapeutic Potential of Phosphodiesterase (PDE) Inhibitors Against Neurodegeneration: the Perspective of the Medicinal Chemist
Ribeiro-Carvalho_2020_PLoS.One_15_e0239017Mood-related behavioral and neurochemical alterations in mice exposed to low chlorpyrifos levels during the brain growth spurt
Ribeiro_2020_J.Biol.Chem_295_314A global analysis of function and conservation of catalytic residues in enzymes
Rice_2020_Ann.N.Y.Acad.Sci_1480_136Organoleptic assessment and median lethal dose determination of oral aldicarb in rats
Richardson_2020_Adv.Neurotoxicol_4_1Neuropathy target esterase (NTE/PNPLA6) and organophosphorus compound-induced delayed neurotoxicity (OPIDN)
Rico-Sanchez_2020_Environ.Sci.Pollut.Res.Int__Assessment of seasonal and spatial variations of biochemical markers in Corydalus sp. (Megaloptera: Corydalidae), a non-conventional biomonitor, in a mountain cloud forest in Mexico
Riedel_2020_Curr.Alzheimer.Res__Mechanisms of Anticholinesterase Interference with Tau Aggregation Inhibitor Activity in a Tau-Transgenic Mouse Model
Rima_2020_Sci.Rep_10_15338Dynamic regulation of the cholinergic system in the spinal central nervous system
Rios_2020_J.Nat.Prod__Furofuranone Lignans from Leucophyllum ambiguum
Riquelme_2020_J.Neuroendocrinol__e12914Huperzine-A administration recovers rat ovary function after sympathetic stress
Rishitha_2020_Front.Biosci.(Elite.Ed)_12_79Preventative effects of alpha-naphtho flavone in vascular dementia
Risticevic_2020_Sci.Rep_10_6724Application of in vivo solid phase microextraction (SPME) in capturing metabolome of apple (Malus xdomestica Borkh.) fruit
Rivera_2020_Br.J.Pharmacol__Differential hepatoprotective role of the cannabinoid CB1 and CB2 receptors in acetaminophen-induced liver injury
Rjeibi_2020_Inflammopharmacology_28_563Brachychiton populneus as a novel source of bioactive ingredients with therapeutic effects: antioxidant, enzyme inhibitory, anti-inflammatory properties and LC-ESI-MS profile
Rjeibi_2020_Oxid.Med.Cell.Longev_2020_1903056Characterization of Polysaccharides Extracted from Pulps and Seeds of Crataegus azarolus L. var. aronia: Preliminary Structure, Antioxidant, Antibacterial, alpha-Amylase, and Acetylcholinesterase Inhibition Properties
Roberts_2020_mSphere_5_Environmental Consortium Containing Pseudomonas and Bacillus Species Synergistically Degrades Polyethylene Terephthalate Plastic
Robertson_2020_Genes.(Basel)_11_Immunoreactive Proteins in the Esophageal Gland Cells of Anisakis Simplex Sensu Stricto Detected by MALDI-TOF/TOF Analysis
Rocchetti_2020_Food.Res.Int_127_108712Phenolic profiling and in vitro bioactivity of Moringa oleifera leaves as affected by different extraction solvents
Rocchetti_2020_J.Sci.Food.Agric_100_1998Untargeted metabolomic profiling of three Crataegus species (hawthorn) and their in vitro biological activities
Rocha_2020_Enzyme.Microb.Technol_142_109664Lipases of Endophytic Fungi Stemphylium lycopersici and Sordaria sp.: Application in the synthesis of solketal derived Monoacylglycerols
Rocha_2020_Food.Chem_329_127168Adding value to polyvinylpolypyrrolidone winery residue: A resource of polyphenols with neuroprotective effects and ability to modulate type 2 diabetes-relevant enzymes
Rochais_2020_Br.J.Pharmacol_177_1988Donecopride, a Swiss army knife with potential against Alzheimer's disease
Roda_2020_Comp.Biochem.Physiol.A.Mol.Integr.Physiol__110659Microplastics and copper effects on the neotropical teleost Prochilodus lineatus: Is there any interaction?
Rodolico_2020_Front.Neurol_11_660MuSK-Associated Myasthenia Gravis: Clinical Features and Management
Rodrigues_2020_Environ.Pollut_262_114277Novel understanding of toxicity in a life cycle perspective - The mechanisms that lead to population effect - The case of Ag (nano)materials
Rodrigues_2020_Eur.J.Neurosci__An optimized spectrophotometric assay reveals increased activity of enzymes involved in 2-arachidonoyl glycerol turnover in the cerebral cortex of a rat model of Alzheimer's disease
Rodrigues_2020_Neurotoxicol.Teratol__106929A single dose of the organophosphate triazophos induces fear extinction deficits accompanied by hippocampal acetylcholinesterase inhibition
Rodriguez-Lavado_2020_Eur.J.Med.Chem_198_112368Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer's disease
Rodriguez-Mortera_2020_Clin.Chim.Acta_508_61Higher ANGPTL3, apoC-III, and apoB48 dyslipidemia, and lower lipoprotein lipase concentrations are associated with dysfunctional visceral fat in adolescents with obesity
Rodriguez-Pires_2020_Front.Plant.Sci_11_1286Proteomic Studies to Understand the Mechanisms of Peach Tissue Degradation by Monilinia laxa
Rodriguez-Seijo_2020_Chemosphere_251_126421Chemical availability versus bioavailability of potentially toxic elements in mining and quarry soils
Rojas_2020_Eur.J.Med.Chem_208_112792Combined MD/QTAIM techniques to evaluate ligand-receptor interactions. Scope and limitations
Rojas_2020_Neurobiol.Dis__104863Urethane attenuates early neuropathology of diisopropylfluorophosphate-induced status epilepticus in rats
Romani_2020_Antioxidants.(Basel)_9_Arylesterase Activity of Paraoxonase-1 in Serum and Cerebrospinal Fluid of Patients with Alzheimer's Disease and Vascular Dementia
Romero_2020_Neural.Regen.Res_15_30Highlights of ASS234: a novel and promising therapeutic agent for Alzheimer's disease therapy
Rosales_2020_Fitoterapia_143_104558Indole alkaloids: 2012 until now, highlighting the new chemical structures and biological activities
Rosenberg_2020_Neuropharmacol__108150Acetylcholinesterase inhibition resulting from exposure to inhaled OP can be prevented by pretreatment with BChE in both macaques and minipigs
Rosenberry_2020_Molecules_25_Solvent Deuterium Oxide Isotope Effects on the Reactions of Organophosphorylated Acetylcholinesterase
Rossi_2020_Front.Physiol_11_573492Efficient Cocaine Degradation by Cocaine Esterase-Loaded Red Blood Cells
Rossino_2020_Int.J.Mol.Sci_21_Setup and Validation of a Reliable Docking Protocol for the Development of Neuroprotective Agents by Targeting the Sigma-1 Receptor (S1R)
Rosta_2020_Antioxidants.(Basel)_9_Sex Difference Impacts on the Relationship between Paraoxonase-1 (PON1) and Type 2 Diabetes
Rottke_2020_Chem.Commun.(Camb)__Switching enzyme activity by a temperature responsive inhibitor modified polymer
Rotundo_2020_Neurosci.Lett__135157Acetylcholinesterase at the Neuromuscular Junction
Roy_2020_J.Neuroimmunol_348_577390Probiotics protect against gut dysbiosis associated decline in learning and memory
Royall_2020_Int.J.Geriatr.Psychiatry_35_1341scores predict multiple neuropsychiatric symptoms
Ru_2020_Front.Microbiol_11_442Microbial Degradation and Valorization of Plastic Wastes
Rubin_2020_BMJ.Open_10_e036071Public responses to the Salisbury Novichok incident: a cross-sectional survey of anxiety, anger, uncertainty, perceived risk and avoidance behaviour in the local community
Ruppert_2020_Mol.Metab__101033Fasting induces ANGPTL4 and reduces LPL activity in human adipose tissue
Russell_2020_Pharm.Dev.Technol__1Profiling gene expression dynamics underpinning conventional testing approaches to better inform pre-clinical evaluation of an age appropriate spironolactone formulation
Rusu_2020_Antioxidants.(Basel)_9_Antioxidant Effects of Walnut (Juglans regia L.) Kernel and Walnut Septum Extract in a D-Galactose-Induced Aging Model and in Naturally Aged Rats
Rusu_2020_Molecules_25_Walnut (Juglans regia L.) Septum: Assessment of Bioactive Molecules and In Vitro Biological Effects
Rutkoski_2020_Chemosphere_250_126162Morphological and biochemical traits and mortality in Physalaemus gracilis (Anura: Leptodactylidae) tadpoles exposed to the insecticide chlorpyrifos
Rutul_2020_Phytochemistry_182_112594Study of dynamics of genes involved in biosynthesis and accumulation of scopoletin at different growth stages of Convolvulus prostratus Forssk
Ruuskanen_2020_Environ.Pollut_266_115108Glyphosate-based herbicides influence antioxidants, reproductive hormones and gut microbiome but not reproduction: A long-term experiment in an avian model
Ryu_2020_J.Microbiol.Biotechnol__Identification of a Second Type of AHL-lactonase from Rhodococcus sp. BH4, belonging to the alpha/beta Hydrolase Superfamily
Saad_2020_Inflammopharmacology_28_939Nicotine-induced oxidative stress, testis injury, AChE inhibition and brain damage alleviated by Mentha spicata
Saat_2020_Biotechnol.Appl.Biochem_67_354One-pot lipase-catalyzed esterification of sigma-caprolactone with methyl-d-glucopyranoside and its elongation with free 6-hydroxyhexanoate monomer units
Sabbagh_2020_Alzheimers.Dement_16_641Effects of a combined transcranial magnetic stimulation (TMS) and cognitive training intervention in patients with Alzheimer's disease
Saberi_2020_Drug.Chem.Toxicol__1The pro-convulsant effects of diazinon low dose in male rats under amygdala kindling
Sadeghi_2020_Acta.Neurobiol.Exp.(Wars)_80_108The inhibitory effects of bile acids on catalytic and noncatalytic functions of acetylcholinesterase as a therapeutic target in Alzheimer's disease
Saeedi_2020_Arch.Pharm.(Weinheim)__e2000101Thieno[2,3-b]pyridine amines: Synthesis and evaluation of tacrine analogs against biological activities related to Alzheimer's disease
Saeedi_2020_Arch.Pharm.(Weinheim)__e2000258Novel N-benzylpiperidine derivatives of 5-arylisoxazole-3-carboxamides as anti-Alzheimer's agents
Saeedi_2020_Biomed.Pharmacother_133_110995Association between chronic stress and Alzheimer's disease: Therapeutic effects of Saffron
Saeedi_2020_Chem.Biodivers__Design and synthesis of novel arylisoxazole-chromenone carboxamides: Investigation of biological activities associated with Alzheimer's disease
Saenkham_2020_Fitoterapia__104637Highly potent cholinesterase inhibition of geranylated xanthones from Garcinia fusca and molecular docking studies
Saglik_2020_Molecules_25_Design, Synthesis, and Structure-Activity Relationships of Thiazole Analogs as Anticholinesterase Agents for Alzheimer's Disease
Sagong_2020_ACS.Catal_10_4805Decomposition of the PET Film by MHETase Using Exo-PETase Function
Sagud_2020_J.Enzyme.Inhib.Med.Chem_35_460Design, synthesis and cholinesterase inhibitory properties of new oxazole benzylamine derivatives
SahIn_2020_Turk.J.Chem_44_574Combined ligand and structure-based virtual screening approaches for identification of novel AChE inhibitors
Sahaka_2020_Food.Funct_11_6710The digestion of galactolipids and its ubiquitous function in Nature for the uptake of the essential alpha-linolenic acid
Saidi_2020_Bioorg.Chem_102_104093Anti-tyrosinase, anti-cholinesterase and cytotoxic activities of extracts and phytochemicals from the Tunisian Citharexylum spinosum L.: Molecular docking and SAR analysis
Saikia_2020_ACS.Comb.Sci_22_630Diversity-Oriented Synthesis of Thiazolidine-2-imines via Microwave-Assisted One-Pot, Telescopic Approach and Its Interaction with Biomacromolecules
Sakai_2020_Cancer.Chemother.Pharmacol__Assessment of pharmacokinetic variations of capecitabine after multiple administration in rats: a physiologically based pharmacokinetic model
Sakata_2020_Bioorg.Chem_103_104201Synthesis and biological evaluation of 2'-Aminochalcone: A multi-target approach to find drug candidates to treat Alzheimer's disease
Sakurada_2020_Leg.Med.(Tokyo)_47_101761No promising antidote 25 years after the Tokyo subway sarin attack: A review
Salau_2020_Arch.Physiol.Biochem__1Kolaviron modulates dysregulated metabolism in oxidative pancreatic injury and inhibits intestinal glucose absorption with concomitant stimulation of muscle glucose uptake
Salau_2020_Biol.Trace.Elem.Res_196_517Ferric-Induced Pancreatic Injury Involves Exacerbation of Cholinergic and Proteolytic Activities, and Dysregulation of Metabolic Pathways: Protective Effect of Caffeic Acid
Salau_2020_J.Biochem.Mol.Toxicol__e22610Caffeic acid improves glucose utilization and maintains tissue ultrastructural morphology while modulating metabolic activities implicated in neurodegenerative disorders in isolated rat brains
Salau_2020_J.Food.Biochem__e13597Modulatory effect of ursolic acid on neurodegenerative activities in oxidative brain injury: An ex vivo study
Salau_2020_J.Pharm.Pharmacol_72_1787Catechol protects against iron-mediated oxidative brain injury by restoring antioxidative metabolic pathways; and modulation of purinergic and cholinergic enzymes activities
Salau_2020_Metab.Brain.Dis__Vanillin and vanillic acid modulate antioxidant defense system via amelioration of metabolic complications linked to Fe(2+)-induced brain tissues damage
Salau_2020_Neurotox.Res_37_944Ferulic Acid Modulates Dysfunctional Metabolic Pathways and Purinergic Activities, While Stalling Redox Imbalance and Cholinergic Activities in Oxidative Brain Injury
Salazar-Tortosa_2020_Pediatr.Diabetes__Association between LPL gene polymorphisms and cardiovascular disease risk factors in European adolescents: The HELENA study
Saldivar-Gonzalez_2020_J.Cheminform_12_64Chemoinformatics-based enumeration of chemical libraries: a tutorial
Saleem_2020_ACS.Omega_5_25216Anti-Parkinson's Activity of Tribulus terrestris via Modulation of AChE, alpha-Synuclein, TNF-alpha, and IL-1beta
Saleem_2020_Drug.Dev.Ind.Pharm__1UHPLC-MS Phytochemical profiling, biological propensities and in-silico studies of Alhagi maurorum roots: A medicinal herb with multifunctional properties
Saleem_2020_Food.Res.Int_137_109651Therapeutic propensities, phytochemical composition, and toxicological evaluation of Anagallis arvensis (L.): A wild edible medicinal food plant
Saleem_2020_Nat.Prod.Res_34_2602Phytochemical profiling, antioxidant, enzyme inhibition and cytotoxic potential of Bougainvillea glabra flowers
Saleh_2020_J.Chem.Neuroanat__101878Dual Prophylactic/Therapeutic Potential of Date Seed, and Nigella and Olive Oils-based Nutraceutical Formulation in Rats with Experimentally-Induced Alzheimer's Disease: A Mechanistic Insight
Salem Al-Howiti_2020_Mar.Pollut.Bull_150_110766Use of Tridacna maxima, a bivalve in the biomonitoring of the Saudi Arabian Red Sea coast
Salem_2020_Int.Immunopharmacol_84_106514Effect of low dose metronomic therapy on MCF-7 tumor cells growth and angiogenesis. Role of muscarinic acetylcholine receptors
Salem_2020_Toxicol.Ind.Health__748233720940538Altered tumor suppressor genes expression in Egyptian pesticide applicators exposed to organophosphate insecticides
Salgado_2020_Food.Chem_337_127954Identification and characterization of a polyurethanase with lipase activity from Serratia liquefaciens isolated from cold raw cow's milk
Salhi_2020_Biochimie_169_106Characterization of all the lipolytic activities in pancreatin and comparison with porcine and human pancreatic juices
Saliu_2020_J.Ethnopharmacol__113284Abatement of neurobehavioral and neurochemical dysfunctions in cerebral ischemia/reperfusion injury by Tetrapleura tetraptera fruit extract
Sallam_2020_Nat.Prod.Res__1New prenylated flavonoid and neuroprotective compounds from Tephrosia purpurea subsp. dunensis
Salleh_2020_Microorganisms_8_1738A Host-Vector System for the Expression of a Thermostable Bacterial Lipase in a Locally Isolated Meyerozyma guilliermondii SMB
Salleh_2020_Z.Naturforsch.C.J.Biosci__Chemical composition and anticholinesterase inhibitory activity of Pavetta graciliflora Wall. ex Ridl. essential oil
Salvi_2020_ACS.Omega_5_22940Chemoenzymatic Epoxidation of Limonene Using a Novel Surface-Functionalized Silica Catalyst Derived from Agricultural Waste
Samad_2020_Medicina.(Kaunas)_56_Behavioral and Biochemical Effects of Mukia madrespatana Following Single Immobilization Stress on Rats
Samad_2020_Pak.J.Pharm.Sci_33_2293Diet supplements of banana fruit pulp mitigates repeated noise stress induced behavioral deficits and oxidative stress
Samak_2020_Environ.Int_145_106144Recent advances in biocatalysts engineering for polyethylene terephthalate plastic waste green recycling
Samare_2020_Chemosphere_240_124887A survey of the secondary exposure to organophosphate and organochlorine pesticides and the impact of preventive factors in female villagers
Sanahuja_2020_Aquat.Toxicol_228_105617Multi-organ characterisation of B-esterases in the European sea bass (Dicentrarchus labrax): Effects of the insecticide fipronil at two temperatures
Sanchez-Castellano_2020_J.Cachexia.Sarcopenia.Muscle__Biomarkers of sarcopenia in very old patients with hip fracture
Sanchez-Hernandez_2020_J.Hazard.Mater__124405Earthworms increase the potential for enzymatic bio-activation of biochars made from co-pyrolyzing animal manures and plastic wastes
Sanchez-Marin_2020_Aquat.Toxicol_230_105688Proteomic analysis and biochemical alterations in marine mussel gills after exposure to the organophosphate flame retardant TDCPP
Sanchis_2020_Amino.Acids__Acetylcholinesterase inhibitory activity of a naturally occurring peptide isolated from Boana pulchella (Anura: Hylidae) and its analogs
Sandeu_2020_PLoS.One_15_e0240743A differential expression of pyrethroid resistance genes in the malaria vector Anopheles funestus across Uganda is associated with patterns of gene flow
Sang_2020_Crit.Rev.Microbiol__1Research on endophytic fungi for producing huperzine A on a large-scale
Sang_2020_Eur.J.Med.Chem_194_112265Design, synthesis and biological evaluation of novel O-carbamoyl ferulamide derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease
Sani_2020_J.Biomol.Struct.Dyn__1Floral extracts-mediated green synthesis of NiO nanoparticles and their diverse pharmacological evaluations
Sankar_2020_Int.J.Biol.Macromol_164_3546Less explored plant lipases: Modeling and molecular dynamics simulations of plant lipases in different solvents and temperatures to understand structure-function relationship
Santana_2020_Sci.Total.Environ__143829Pesticide effects on fish cholinesterase variability and mean activity: A meta-analytic review
Santi_2020_Eur.J.Med.Chem_206_112718Neuroprotective effects of prenylated flavanones isolated from Dalea species, in vitro and in silico studies
Santoro_2020_Syst.Biol.Reprod.Med__1Sperm performance in oligoasthenoteratozoospermic patients is induced by a nutraceuticals mix, containing mainly myo-inositol
Santos_2020_Biomolecules_10_Prolyl Endopeptidase-Like Facilitates the alpha-Synuclein Aggregation Seeding, and This Effect Is Reverted by Serine Peptidase Inhibitor PMSF
Santos_2020_Bioorg.Med.Chem__115470Acylhydrazones as isoniazid derivatives with multi-target profiles for the treatment of Alzheimer's disease: Radical scavenging, myeloperoxidase/acetylcholinesterase inhibition and biometal chelation
Santoso_2020_Curr.Cardiol.Rev_16_3Phospholipase A2 is an Inflammatory Predictor in Cardiovascular Diseases: Is there any Spacious Room to Prove the Causation?
Saraon_2020_J.Am.Geriatr.Soc_68_216Screening for Adverse Drug Reactions in Dementia Patients on Cholinesterase Inhibitor Therapy
Sarfaraz_2020_Pak.J.Pharm.Sci_33_2831Anxiolytic and memory enhancing potential of aloe vera and flax seed oil in rats: A comparative study with valproic acid
Sarikurkcu_2020_Molecules_25_Enzyme and Biological Activities of the Water Extracts from the Plants Aesculus hippocastanum, Olea europaea and Hypericum perforatum That Are Used as Folk Remedies in Turkey
Sarkar_2020_Microb.Cell.Fact_19_77Characterization of a novel family VIII esterase EstM2 from soil metagenome capable of hydrolyzing estrogenic phthalates
Sarmadi_2020_Adv.Biomed.Res_9_25Molecular Genetic Study in a Cohort of Iranian Families Suspected to Maturity-Onset Diabetes of the Young, Reveals a Recurrent Mutation and a High-Risk Variant in the CEL Gene
Sarter_2020_J.Neurosci_40_712Forebrain Cholinergic Signaling: Wired and Phasic, Not Tonic, and Causing Behavior
Saso_2020_Ann.Surg.Oncol_27_4337Dipeptidyl Peptidase 9 Increases Chemoresistance and is an Indicator of Poor Prognosis in Colorectal Cancer
Sathya_2020_Colloids.Surf.B.Biointerfaces_190_110948Deciphering the anti-apoptotic potential of alpha-bisabolol loaded solid lipid nanoparticles against Abeta induced neurotoxicity in Neuro-2a cells
Sathya_2020_Nutr.Neurosci__1Phytol loaded PLGA nanoparticles ameliorate scopolamine-induced cognitive dysfunction by attenuating cholinesterase activity, oxidative stress and apoptosis in Wistar rat
Savall_2020_Basic.Clin.Pharmacol.Toxicol_126_399Pre-clinical evidence of safety and protective effect of isatin and oxime derivatives against malathion-induced toxicity
Savall_2020_Life.Sci__117892Antidepressant-like effect of (3Z)-5-Chloro-3-(hydroxyimino)indolin-2-one in rats exposed to malathion: Involvement of BDNF-Trkbeta pathway and AChE
Scalisi_2020_Toxicol.Res.(Camb)_9_537Evaluation of dimethoate toxicity on fertilization and on embryonic development of Paracentrotus lividus (Lamarck, 1816)
Schafer_2020_J.Biol.Chem_295_18604Neuroligin-2 dependent conformational activation of collybistin reconstituted in supported hybrid membranes
Scheaffer_2020_ACS.Omega_5_29177Inactivation of CES1 Blocks Prostaglandin D(2) Glyceryl Ester Catabolism in Monocytes/Macrophages and Enhances Its Anti-inflammatory Effects, Whereas the Pro-inflammatory Effects of Prostaglandin E(2) Glyceryl Ester Are Attenuated
Scheide_2020_Org.Biomol.Chem__Electrochemical synthesis of selenyl-dihydrofurans via anodic selenofunctionalization of allyl-naphthol/phenol derivatives and their anti-Alzheimer activity
Schenkmayerova_2020_ChemRxiv__Engineering Protein Dynamics of Ancestral Luciferase
Schimidt_2020_Exp.Gerontol_143_111186Strength training or green tea prevent memory deficits in a beta-amyloid peptide-mediated Alzheimer's disease model
Schintu_2020_Front.Pharmacol_11_304Non-dopaminergic Alterations in Depression-Like FSL Rats in Experimental Parkinsonism and L-DOPA Responses
Schittmayer_2020_Mol.Cell.Proteomics_19_2104Spatially resolved activity-based proteomic profiles of the murine small intestinal lipases
Schmitt_2020_Toxicol.Appl.Pharmacol_408_115275Transgenerational effects of developmental exposure to chlorpyrifos-oxon in zebrafish (DANIO RERIO)
Scholz_2020_Eur.J.Med.Chem_185_111766Soluble epoxide hydrolase inhibitors with carboranes as non-natural 3-D pharmacophores
Schopfer_2020_Molecules_25_Signature Ions in MS/MS Spectra for Dansyl-Aminohexyl-QQIV Adducts on Lysine
Schrenk_2020_EFSA.J_18_e06222Risk assessment of glycoalkaloids in feed and food, in particular in potatoes and potato-derived products
Schulz_2020_Sci.Rep_10_16539The crystal structure of mycobacterial epoxide hydrolase A
Scicutella_2020_Expert.Opin.Pharmacother__1The pharmacotherapeutic management of postoperative delirium: an expert update
Scuteri_2020_Eur.J.Clin.Pharmacol__Pattern of treatment of behavioural and psychological symptoms of dementia and pain: evidence on pharmacoutilization from a large real-world sample and from a centre for cognitive disturbances and dementia
Secnik_2020_BMJ.Open.Diabetes.Res.Care_8_Cholinesterase inhibitors in patients with diabetes mellitus and dementia: an open-cohort study of ~23 000 patients from the Swedish Dementia Registry
Sedogawa_2020_JA.Clin.Rep_6_17Opposite changes in blood pressure and pulse rate in two patients with distigmine and rivastigmine intoxication
Sejvar_2020_Neurol.Clin_38_881Neurochemical and Neurobiological Weapons
Seki_2020_J.Agric.Food.Chem__Dipeptidyl peptidase-IV inhibitory activity of Katsuobushi-derived peptides in Caco-2 cell assay and oral glucose tolerance test in ICR mice
Sekido_2020_Low.Urin.Tract.Symptoms__EP2 and EP3 receptors as therapeutic targets for underactive bladder/detrusor underactivity due to diabetic cystopathy in a type 1 diabetic rat model
Semenov_2020_Molecules_25_Novel Acetylcholinesterase Inhibitors Based on Uracil Moiety for Possible Treatment of Alzheimer Disease
Sen_2020_J.Neurol_267_2749Bi-allelic variants in PNPLA6 possibly associated with Parkinsonian features in addition to spastic paraplegia phenotype
Senbua_2020_Biotechnol.Rep.(Amst)_27_e00495Easy-to-use and reliable absorbance-based MPH-GST biosensor for the detection of methyl parathion pesticide
Senior_2020_Nature_577_706Improved protein structure prediction using potentials from deep learning
Senizza_2020_Foods_9_The Strength of the Nutrient Solution Modulates the Functional Profile of Hydroponically Grown Lettuce in a Genotype-Dependent Manner
Seo_2020_J.Am.Heart.Assoc_9_e014100Prognostic Significance of Serum Cholinesterase Level in Patients With Acute Decompensated Heart Failure With Preserved Ejection Fraction: Insights From the PURSUIT-HFpEF Registry
Sepehri_2020_Arch.Pharm.(Weinheim)__e2000109Synthesis, characterization, molecular docking, and biological activities of coumarin-1,2,3-triazole-acetamide hybrid derivatives
Sepehri_2020_J.Biomol.Struct.Dyn__1Novel quinazolin-sulfonamid derivatives: synthesis, characterization, biological evaluation, and molecular docking studies
Serrano-Arnaldos_2020_Bioprocess.Biosyst.Eng_43_495Development and economic evaluation of an eco-friendly biocatalytic synthesis of emollient esters
Serseg_2020_Curr.Comput.Aided.Drug.Des__Lepidine B from Lepidium Sativum Seeds as Multi-Functional Anti-Alzheimer's Disease Agent: In Vitro and In Silico Studies
Sever_2020_Int.J.Biol.Macromol_163_1970Thiazolyl-pyrazoline derivatives: In vitro and in silico evaluation as potential acetylcholinesterase and carbonic anhydrase inhibitors
Sevim_2020_Turk.J.Pharm.Sci_17_506In Vitro Investigation of the Effects of Imidacloprid on AChE, LDH, and GSH Levels in the L-929 Fibroblast Cell Line
Sezigen_2020_Toxicol.Lett__In vitro evaluation of two different type of obidoxime-loaded nanoparticles for cytotoxicity and blood-brain barrier transport
Sha_2020_Sci.Total.Environ_752_141784Gestational and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice: Neurobehavioral effects on female offspring
Shahbazi_2020_iScience_23_101301Cannabinoids and Cannabinoid Receptors: The Story so Far
Shahmohammadi_2020_Molecules_25_Efficient Synthesis of New Fluorinated beta-Amino Acid Enantiomers through Lipase-Catalyzed Hydrolysis
Shahwan_2020_J.Biomol.Struct.Dyn__1Understanding binding between donepezil and human ferritin: molecular docking and molecular dynamics simulation approach
Shaikh_2020_Bioorg.Chem_96_103589Design, synthesis and evaluation of pyrazole bearing alpha-aminophosphonate derivatives as potential acetylcholinesterase inhibitors against Alzheimer's disease
Shaikh_2020_J.Biomol.Struct.Dyn__1Synthesis of carbazole based alpha-aminophosphonate derivatives: design, molecular docking and in vitro cholinesterase activity
Shaikh_2020_Mol.Divers__Design, synthesis and evaluation of new chromone-derived aminophosphonates as potential acetylcholinesterase inhibitor
Shakhanova_2020_Biomed.Rep_13_35Association of polymorphism genes LPL , ADRB2 , AGT and AGTR1 with risk of hyperinsulinism and insulin resistance in the Kazakh population
Shakil_2020_J.Biomol.Struct.Dyn__1Molecular interaction of anti-cancer ligands with human brain acetylcholinesterase
Shaku_2020_Front.Cell.Infect.Microbiol_10_603382Cell Surface Biosynthesis and Remodeling Pathways in Mycobacteria Reveal New Drug Targets
Shamsi_2020_Biomolecules_10_MARK4 Inhibited by AChE Inhibitors, Donepezil and Rivastigmine Tartrate: Insights into Alzheimer's Disease Therapy
Shan_2020_Int.J.Mol.Sci_21_Association of alpha/beta-Hydrolase D16B with Bovine Conception Rate and Sperm Plasma Membrane Lipid Composition
Shanbhag_2020_J.Membr.Biol_253_381The Lysophosphatidylserines-An Emerging Class of Signalling Lysophospholipids
Shao_2020_Int.J.Mol.Sci_21_Identification and Functional Study of Chitin Metabolism and Detoxification-Related Genes in Glyphodes pyloalis Walker (Lepidoptera: Pyralidae) Based on Transcriptome Analysis
Shao_2020_Mediators.Inflamm_2020_4694090Serum Cholinesterases, a Novel Marker of Clinical Activity in Inflammatory Bowel Disease: A Retrospective Case-Control Study
Sharan Shrestha_2020_Molecules_25_Himalayan Nettle Girardinia diversifolia as a Candidate Ingredient for Pharmaceutical and Nutraceutical Applications-Phytochemical Analysis and In Vitro Bioassays
Sharifi-Rad_2020_J.Clin.Med_9_Impact of Natural Compounds on Neurodegenerative Disorders: From Preclinical to Pharmacotherapeutics
Sharifkhodaei_2020_Genome__1Overexpressed Gliotactin activates BMP signaling through interfering with the Tkv-Dad association
Sharma_2020_ACS.Omega_5_19654Metal-Free Fluorescent Supramolecular Assemblies for Distinct Detection of Organophosphate/Organochlorine Pesticides
Sharma_2020_Brain.Res__147116Possible involvement of D2/D3 receptor activation in ischemic preconditioning mediated protection of the brain
Sharma_2020_Clin.Nucl.Med_Publish Ahead of Print_Fibroblast Activation Protein Inhibitor PET/CT: A Promising Molecular Imaging Tool
Sharma_2020_Environ.Toxicol.Pharmacol__103454Glycosylated-Imidazole Aldoximes as Reactivators of Pesticides Inhibited AChE: Synthesis and In-vitro Reactivation Study
Sharma_2020_Exp.Brain.Res_238_2293Intracerebroventricular streptozotocin administration impairs mitochondrial calcium homeostasis and bioenergetics in memory-sensitive rat brain regions
Sharma_2020_J.Biomol.Struct.Dyn_38_1822Interaction of Synthesized Nitrogen enriched Graphene Quantum Dots with Novel Anti-Alzheimer's Drugs: Spectroscopic Insights
Sharma_2020_J.Biomol.Struct.Dyn_38_5349Mining of potential dipeptidyl peptidase-IV inhibitors as anti-diabetic agents using integrated in silico approaches
Sharma_2020_J.Biomol.Struct.Dyn__1In silico strategies for probing novel DPP-IV inhibitors as anti-diabetic agents
Sharma_2020_J.Chem.Neuroanat__101784Effect of electromagnetic radiation on redox status, acetylcholine esterase activity and cellular damage contributing to the diminution of the brain working memory in rats
Sharma_2020_Methods.Mol.Biol_2089_257Cholinesterase as a Target for Drug Development in Alzheimer's Disease
Sharna_2020_Front.Cell.Neurosci_14_85Altered Caecal Neuroimmune Interactions in the Neuroligin-3(R451C) Mouse Model of Autism
Shaydenfish_2020_Neuropharmacol__108134The effects of acetylcholinesterase inhibitors on morbidity after general anesthesia and surgery
Shehata_2020_J.Mol.Model_26_122Understanding thermal and organic solvent stability of thermoalkalophilic lipases: insights from computational predictions and experiments
Shehata_2020_J.Phys.Chem.B_124_8801Lipase and Water in a Deep Eutectic Solvent: Molecular Dynamics and Experimental Studies of the Effects of Water-In-Deep Eutectic Solvents on Lipase Stability
Sheikh_2020_Pak.J.Pharm.Sci_33_2239Derivatives of diisopropyl phenoxyphosphate with controlled reactivity for enhancement of Acetylcholine (ACh) neurotransmitter
Shen_2020_Eur.J.Med.Chem_208_112850Structural optimization of pyrazolo[1,5-a]pyrimidine derivatives as potent and highly selective DPP-4 inhibitors
Shen_2020_Fitoterapia__104737Limonoids with diverse structures of rings-A,B from the Thai mangrove, Xylocarpus moluccensis
Shen_2020_Front.Pharmacol_11_595254Network Pharmacology-Based Analysis of Xiao-Xu-Ming Decoction on the Treatment of Alzheimer's Disease
Shen_2020_Insects_11_Biochemical Mechanisms, Cross-resistance and Stability of Resistance to Metaflumizone in Plutella xylostella
Shen_2020_J.Hazard.Mater__124342Lysosome targeting metal-organic framework probe LysFP@ZIF-8 for highly sensitive quantification of carboxylesterase 1 and organophosphates in living cells
Shen_2020_Sci.Total.Environ_732_139333The influence mechanism of temperature on solid phase denitrification based on denitrification performance, carbon balance, and microbial analysis
Shenhar-Tsarfaty_2020_Atherosclerosis_313_144Blood acetylcholinesterase activity is associated with increased 10 year all-cause mortality following coronary angiography
Shenoy_2020_Mol.Pharm_17_1706Chemoproteomic Identification of Serine Hydrolase RBBP9 as a Valacyclovir-Activating Enzyme
Shentema_2020_Int.J.Environ.Res.Public.Health_17_Pesticide Use and Serum Acetylcholinesterase Levels among Flower Farm Workers in Ethiopia-A Cross-Sectional Study
Sheynin_2020_J.Neurosci__Cholinergic modulation of binocular vision
Shi_2020_BMB.Rep_53_658Hypermethylation-mediated silencing of NDRG4 promotes pancreatic ductal adenocarcinoma by regulating mitochondrial function
Shi_2020_Environ.Pollut_266_115345Exposure to acetamiprid influences the development and survival ability of worker bees (Apis mellifera L.) from larvae to adults
Shi_2020_J.Hazard.Mater_409_124999In vitro biolayer interferometry analysis of acetylcholinesterase as a potential target of aryl-organophosphorus flame-retardants
Shi_2020_J.Insect.Sci_20_Effects of Quercetin on the Growth and Expression of Immune-Pathway-Related Genes in Silkworm (Lepidoptera: Bombycidae)
Shi_2020_Mol.Genet.Genomic.Med__e1048Identification and functional characterization of a novel heterozygous missense variant in the LPL associated with recurrent hypertriglyceridemia-induced acute pancreatitis in pregnancy
Shi_2020_Proteomics__e2000175FRACPRED-2D-PRM: A fraction prediction algorithm-assisted two-dimensional liquid chromatography-based parallel reaction monitoring-mass spectrometry approach for measuring low-abundance proteins in human plasma
Shi_2020_Sci.Rep_10_7031Preparation of porous materials by selective enzymatic degradation: effect of in vitro degradation and in vivo compatibility
Shihadih_2020_Front.Vet.Sci_7_580Selection of Potent Inhibitors of Soluble Epoxide Hydrolase for Usage in Veterinary Medicine
Shimada_2020_J.Surg.Oncol__Long-term prognostic factors of patients with hepatocellular carcinoma who survive over 10 years after hepatectomy
Shin_2020_Free.Radic.Res__1An adenoviral vector encoded with the GPx-1 gene attenuates memory impairments induced by beta-amyloid (1-42) in GPx-1 KO mice via activation of M1 mAChR-mediated signaling
Shin_2020_Pharmazie_75_656Pharmacological evaluation and safety of a donepezil patch
Shin_2020_Sci.Rep_10_83Aberrant expression of S-SCAM causes the loss of GABAergic synapses in hippocampal neurons
Shiry_2020_Vet.Res.Forum_11_325A bioassay on tissue cholinesterase activity of Rutilus kutum (Kamensky, 1901) exposed to some common pesticides in Iran
Shono_2020_Surg.Case.Rep_6_4Congenital hyperinsulinism associated with Hirschsprung's disease-a report of an extremely rare case
Siafaka_2020_CNS.Neurol.Disord.Drug.Targets_19_360Transdermal Drug Delivery Systems and their Potential in Alzheimer's Disease Management
Sibanyoni_2020_Fitoterapia__104650Isolation, in vitro evaluation and molecular docking of acetylcholinesterase inhibitors from South African Amaryllidaceae
Sibomana_2020_J.Toxicol.Environ.Health.A__121-Day dermal exposure to aircraft engine oils: effects on esterase activities in brain and liver tissues, blood, plasma, and clinical chemistry parameters for Sprague Dawley rats
Sikandar_2020_Nat.Chem.Biol_16_1013The bottromycin epimerase BotH defines a group of atypical alpha/beta-hydrolase-fold enzymes
Sikora_2020_J.Enzyme.Inhib.Med.Chem_35_1743Quetiapine and novel PDE10A inhibitors potentiate the anti-BuChE activity of donepezil
Silva-Garcia_2020_Biorxiv__Dipeptidyl peptidase 9 triggers BRCA2 degradation by the N-degron pathway to promote DNA-damage repair
Silva_2020_Acta.Trop_214_105789Effects of a solid formulation containing lectin-rich fraction of Moringa oleifera seeds on egg hatching and development of Aedes aegypti larvae
Silva_2020_Birth.Defects.Res__Effects of low-dose chlorpyrifos on neurobehavior and potential mechanisms: A review of studies in rodents, zebrafish, and Caenorhabditis elegans
Silva_2020_Ecotoxicol.Environ.Saf_205_111340Severe damages caused by Malathion exposure in Colossoma macropomum
Silva_2020_Ecotoxicol.Environ.Saf_207_111375Lumbriculus variegatus (oligochaeta) exposed to polyethylene microplastics: biochemical, physiological and reproductive responses
Silva_2020_Int.J.Mol.Sci_22_Model Amphipathic Peptide Coupled with Tacrine to Improve Its Antiproliferative Activity
Silva_2020_J.Chem.Inf.Model__Donepezil Inhibits Acetylcholinesterase via Multiple Binding Modes at Room Temperature
Silvestrini_2020_Int.J.Biol.Macromol__Principles of lipid-enzyme interactions in the limbus region of the catalytic site of Candida antarctica Lipase B
Simma_2020_Exp.Appl.Acarol_82_475Acaricide resistance status and identification of resistance mutations in populations of the two-spotted spider mite Tetranychus urticae from Ethiopia
Simonsen_2020_Chem.Biol.Interact__109247Benoxacor is enantioselectively metabolized by rat liver subcellular fractions
Sims_2020_J.Anaesthesiol.Clin.Pharmacol_36_465Decrease in heart rate following the administration of sugammadex in adults
Sinan_2020_Antioxidants.(Basel)_9_Biopotential of Bersama abyssinica Fresen Stem Bark Extracts: UHPLC Profiles, Antioxidant, Enzyme Inhibitory, and Antiproliferative Propensities
Sinan_2020_Biomolecules_10_Evaluation of Pharmacological and Phytochemical Profiles Piptadeniastrum africanum (Hook.f.) Brenan Stem Bark Extracts
Sinan_2020_J.Food.Biochem__e13169Novel insights into the fruit and seed extracts of Morinda morindoides (Baker) Milne-Redh: HPLC-ESI-Q-TOF-MS profiling, antioxidant, and enzyme inhibitory propensities
Sinan_2020_J.Pharm.Biomed.Anal_192_113678HPLC-FRAP methodology and biological activities of different stem bark extracts of Cajanus cajan (L.) Millsp
Sinan_2020_Molecules_25_Qualitative Phytochemical Fingerprint and Network Pharmacology Investigation of Achyranthes aspera Linn. Extracts
Singh_2020_Biochemistry__Mapping the neuroanatomy of ABHD16A-ABHD12 & lysophosphatidylserines provides new insights into the pathophysiology of the human neurological disorder PHARC
Singh_2020_Bioorg.Med.Chem.Lett_30_127477New coumarin-benzotriazole based hybrid molecules as inhibitors of acetylcholinesterase and amyloid aggregation
Singh_2020_Biotechnol.Prog_36_e2936Understanding the mechanism of copurification of difficult to remove host cell proteins in rituximab biosimilar products
Singh_2020_Can.J.Physiol.Pharmacol__Meclizine ameliorates memory deficits in streptozotocin-induced experimental dementia in mice: Role of nuclear pregnane x receptors
Singh_2020_Curr.Neurovasc.Res_17_686Agonism of Histaminergic-H(1) Receptors in Ischemic Postconditioning During Cerebral Ischemia-Reperfusion Injury is Protective
Singh_2020_Curr.Neurovasc.Res__Agonism of histaminergic-H1 receptors in ischemic postconditioning during cerebral ischemia-reperfusion injury is protective
Singh_2020_Diabetes.Metab.Syndr_15_159Non-insulin anti-diabetic agents in patients with type 2 diabetes and COVID-19: A Critical Appraisal of Literature
Singh_2020_Dig.Dis.Sci_65_141Acetylcholinesterase Inhibitor Pyridostigmine Bromide Attenuates Gut Pathology and Bacterial Dysbiosis in a Murine Model of Ulcerative Colitis
Singh_2020_Environ.Sci.Pollut.Res.Int__Maximum contaminant level of arsenic in drinking water potentiates quinalphos-induced renal damage on co-administration of both arsenic and quinalphos in Wistar rats
Singh_2020_Eur.J.Med.Chem_198_112257Design, synthesis and biological evaluation of novel naturally-inspired multifunctional molecules for the management of Alzheimer's disease
Singh_2020_Int.J.Biol.Macromol_164_3943Nano-interface driven electrochemical sensor for pesticides detection based on the acetylcholinesterase enzyme inhibition
Singh_2020_J.Basic.Clin.Physiol.Pharmacol__Kinetic characterization of rat brain acetylcholinesterase modulated by lead and cartap: the ameliorative effect of Citrus limon fruit juice
Singh_2020_J.Biomol.Struct.Dyn__1Molecular dynamics simulation and free energy calculation studies of Coagulin L as dipeptidyl peptidase-4 inhibitor
Singh_2020_J.Nat.Prod_83_3689N-Benzyl-linoleamide, a Constituent of Lepidium meyenii (Maca), Is an Orally Bioavailable Soluble Epoxide Hydrolase Inhibitor That Alleviates Inflammatory Pain
Singh_2020_J.Nat.Prod__N-Benzyl-linoleamide, a Constituent of Lepidium meyenii (Maca), Is an Orally Bioavailable Soluble Epoxide Hydrolase Inhibitor That Alleviates Inflammatory Pain
Sinha_2020_Chemosphere__129488Toxicokinetic analysis of commonly used pesticides using data on acute poisoning cases from Hyderabad, South India
Siqueira_2020_Appl.Biochem.Biotechnol_190_1242Bovine Endometritis and the Inflammatory Peripheral Cholinergic System
Sirajuddin_2020_Int.J.Biol.Macromol_145_445A comparative study on degradation of complex malathion organophosphate using of Escherichia coli IES-02 and a novel carboxylesterase
Sirish_2020_Stem.Cells.Transl.Med_9_1570Suppression of inflammation and fibrosis using soluble epoxide hydrolase inhibitors enhances cardiac stem cell-based therapy
Sirish_2020_Stem.Cells.Transl.Med__Suppression of inflammation and fibrosis using soluble epoxide hydrolase inhibitors enhances cardiac stem cell-based therapy
Sisila_2020_Appl.Biochem.Biotechnol__Esterification of Polymeric Carbohydrate Through Congener Cutinase-Like Biocatalyst
Skoczinski_2020_ACS.Omega_5_1488Lipase-Catalyzed Transamidation of Urethane-Bond-Containing Ester
Skoczinski_2020_Colloid.Polym.Sci__Enzymatic transesterification of urethane-bond containing ester
Sledziowska_2020_Neurosci_445_31Evidence for a Contribution of the Nlgn3/Cyfip1/Fmr1 Pathway in the Pathophysiology of Autism Spectrum Disorders
Slusarczyk_2020_Int.J.Mol.Sci_21_Norditerpenoids with Selective Anti-Cholinesterase Activity from the Roots of Perovskia atriplicifolia Benth
Smach_2020_Curr.Pharm.Biotechnol_21_480Arthrophytum scoparium Extract Improves Memory Impairment and Affects Acetylcholinesterase Activity In Mice Brain
Smeriglio_2020_Phytother.Res__Promising in vitro antioxidant, anti-acetylcholinesterase and neuroactive effects of essential oil from two non-psychotropic Cannabis sativa L. biotypes
Smith_2020_Alzheimers.Dement.(N.Y)_6_e12056Canadian Consensus Conference on Diagnosis and Treatment of Dementia (CCCDTD)5: Guidelines for management of vascular cognitive impairment
Soares_2020_Amino.Acids__Hypermethioninemia induces memory deficits and morphological changes in hippocampus of young rats: implications on pathogenesis
Soares_2020_J.Agric.Food.Chem__QSAR modeling and docking of monoterpenes with insecticidal activity against Reticulitermes chinensis Snyder and Drosophila melanogaster
Soares_2020_Neurotoxicol_77_60Methionine and methionine sulfoxide induces neurochemical and morphological changes in cultured astrocytes: Involvement of Na(+), K(+)-ATPase activity, oxidative status, and cholinergic and purinergic signaling
Sobala_2020_ACS.Cent.Sci_6_760An Epoxide Intermediate in Glycosidase Catalysis
Sobolova_2020_Eur.J.Med.Chem_203_112593Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile
Sobstyl_2020_J.Chromatogr.A__460942Effect directed analysis and TLC screening of Schisandra chinensis fruits
Sole_2020_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_242_108940Biochemical aspects of susceptibility to stressors in two small cyprinids Squalius laietanus and Barbus meridionalis from the NW Mediterranean
Sole_2020_Environ.Sci.Pollut.Res.Int_27_31854Biomarker considerations in monitoring petrogenic pollution using the mussel Mytilus galloprovincialis
Sole_2020_Environ.Sci.Pollut.Res.Int__Biomarker considerations in monitoring petrogenic pollution using the mussel Mytilus galloprovincialis
Sole_2020_Environ.Toxicol.Pharmacol__103561The use of an in vitro approach to assess marine invertebrate carboxylesterase responses to chemicals of environmental concern
Solerte_2020_Acta.Diabetol_57_779Dipeptidyl peptidase-4 (DPP4) inhibition in COVID-19
Solerte_2020_Acta.Diabetol__Dipeptidyl peptidase-4 (DPP4) inhibition in COVID-19
Sollier_2020_Ann.Endocrinol.(Paris)_81_51Lipodystrophic syndromes: From diagnosis to treatment
Son_2020_Enzyme.Microb.Technol_141_109656Structural bioinformatics-based protein engineering of thermo-stable PETase from Ideonella sakaiensis
Sonei_2020_Prev.Nutr.Food.Sci_25_65Protective Effects of Berberis vulgaris on Diazinon-Induced Brain Damage in Young Male Mice
Song_2020_Acta.Radiol__284185120940264Possible neuroprotective effects of rasagiline in Alzheimer's disease: a SPECT study
Song_2020_Adv.Sci.(Weinh)_7_2001546Fluoride-Free 2D Niobium Carbide MXenes as Stable and Biocompatible Nanoplatforms for Electrochemical Biosensors with Ultrahigh Sensitivity
Song_2020_Evid.Based.Complement.Alternat.Med_2020_2804849In Vitro and In Vivo Anti-AChE and Antioxidative Effects of Schisandra chinensis Extract: A Potential Candidate for Alzheimer's Disease
Song_2020_Food.Funct__Discovery of hCES2A inhibitors from Glycyrrhiza inflata via combination of docking-based virtual screening and fluorescence-based inhibition assays
Song_2020_Nat.Prod.Res__1Diketopiperazine and enterotoxin analogues from the mangrove derived-soil Streptomyces sp. SCSIO 41400 and their biological evaluation
Song_2020_Plants.(Basel)_9_Screening of Bioactive Metabolites and Biological Activities of Calli, Shoots, and Seedlings of Mertensia maritima (L.) Gray
Soraya_2020_Arch.Med.Res__Metformin Increases Exosome Biogenesis and Secretion in U87 MG Human Glioblastoma Cells: A Possible Mechanism of Therapeutic Resistance
Soto-Mercado_2020_PLoS.One_15_e0221669Cholinergic-like neurons carrying PSEN1 E280A mutation from familial Alzheimer's disease reveal intraneuronal sAPPbeta fragments accumulation, hyperphosphorylation of TAU, oxidative stress, apoptosis and Ca2+ dysregulation: Therapeutic implications
Soufari_2020_Proc.Natl.Acad.Sci.U.S.A_117_29851Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis
Soulis_2020_Molecules_25_Facile and Low-Cost SPE Modification Towards Ultra-Sensitive Organophosphorus and Carbamate Pesticide Detection in Olive Oil
Soumya_2020_Curr.Microbiol_77_3024Pineapple Peel Extract as an Effective Substrate for Esterase Production from Bacillus subtilis E9
Soumya_2020_Curr.Microbiol__Pineapple Peel Extract as an Effective Substrate for Esterase Production from Bacillus subtilis E9
Souza_2020_ACS.Omega_5_4490Molecular Modeling Study of Uncharged Oximes Compared to HI-6 and 2-PAM Inside Human AChE Sarin and VX Conjugates
Souza_2020_Toxicology__152504Evaluation of Mn exposure in the male reproductive system and its relationship with reproductive dysfunction in mice
Spampanato_2020_J.Pharmacol.Exp.Ther_375_59Delayed Adjunctive Treatment of Organophosphate-Induced Status Epilepticus in Rats with Phenobarbital, Memantine, or Dexmedetomidine
Specht_2020_Neuropharmacol_169_107493Fractional occupancy of synaptic binding sites and the molecular plasticity of inhibitory synapses
Spieker_2020_Int.Immunopharmacol_83_106405Cholinergic control of bone development and beyond
Spieler_2020_J.Psychiatr.Res_124_29Donepezil, a cholinesterase inhibitor used in Alzheimer's disease therapy, is actively exported out of the brain by abcb1ab p-glycoproteins in mice
Sridhar_2020_Arch.Pharm.(Weinheim)__e2000048Design, synthesis, evaluation, and molecular modeling studies of indolyl oxoacetamides as potential pancreatic lipase inhibitors
Sritalahareuthai_2020_Foods_9_Phenolic Profiles, Antioxidant, and Inhibitory Activities of Kadsura heteroclita (Roxb.) Craib and Kadsura coccinea (Lem.) A.C. Sm
Srivastava_2020_Bioessays__e1900208Ric-8A, a GEF, and a Chaperone for G Protein alpha-Subunits: Evidence for the Two-Faced Interface
Srivastava_2020_Genes.(Basel)_11_Haplotype-Based Genome-Wide Association Study and Identification of Candidate Genes Associated with Carcass Traits in Hanwoo Cattle
Staer_2020_Parkinsonism.Relat.Disord_81_89Cortical cholinergic dysfunction correlates with microglial activation in the substantia innominata in REM sleep behavior disorder
Stasilowicz_2020_J.Enzyme.Inhib.Med.Chem_35_1811Hydroxypropyl-beta-cyclodextrin as an effective carrier of curcumin - piperine nutraceutical system with improved enzyme inhibition properties
Stavniichuk_2020_Prostaglandins.Other.Lipid.Mediat__106472Dual Soluble Epoxide Hydrolase Inhibitor/PPAR-gamma Agonist Attenuates Renal Fibrosis
Stavrakov_2020_Molecules_25_Galantamine-Curcumin Hybrids as Dual-Site Binding Acetylcholinesterase Inhibitors
Stefanovski_2020_Prostaglandins.Other.Lipid.Mediat__106410Assessment of Soluble Epoxide Hydrolase Activity In Vivo: A Metabolomic Approach
Stefanucci_2020_J.Food.Biochem__e13377Viscum album L. homogenizer-assisted and ultrasound-assisted extracts as potential sources of bioactive compounds
Stephanie_2020_Nat.Prod.Res__1Dewerin and gilbertionol two new secondary metabolites from the stem bark of Gilbertiodendron dewevrei (De Wild) J. Leonard
Stepnik_2020_Int.J.Mol.Sci_21_In Silico Studies on Triterpenoid Saponins Permeation through the Blood-Brain Barrier Combined with Postmortem Research on the Brain Tissues of Mice Affected by Astragaloside IV Administration
Stojanovski_2020_Enzyme.Microb.Technol_139_109592Identification and catalytic properties of new epoxide hydrolases from the genomic data of soil bacteria
Strom_2020_Proteins_88_440Lysosomal acid lipase does not have a propeptide and should not be considered being a proprotein
Struk_2020_Mol.Cell.Proteomics__Unraveling the MAX2 Protein Network in Arabidopsis thaliana: Identification of the Protein Phosphatase PAPP5 as a Novel MAX2 Interactor
Stutz_2020_J.Chromatogr.A_1624_461239Identification of acetylcholinesterase inhibitors in water by combining two-dimensional thin-layer chromatography and high-resolution mass spectrometry
Su_2020_Enzyme.Microb.Technol_133_109467Cutinases as stereoselective catalysts: Specific activity and enantioselectivity of cutinases and lipases for menthol and its analogs
Su_2020_Front.Plant.Sci_11_726Genome-Wide Identification, Evolution, and Expression of GDSL-Type Esterase/Lipase Gene Family in Soybean
Su_2020_Int.J.Biol.Macromol_162_1752Enhanced activity towards polyacrylates and poly(vinyl acetate) by site-directed mutagenesis of Humicola insolens cutinase
Su_2020_Neurochem.Int__104794Inhibitory Potency of 4- Substituted Sampangine Derivatives toward Cu(2+) mediated aggregation of amyloid beta-peptide, Oxidative Stress, and Inflammation in Alzheimer's Disease
Suarez-Lopez_2020_Environ.Res_188_109728Residential proximity to greenhouse crops and pesticide exposure (via acetylcholinesterase activity) assessed from childhood through adolescence
Sueyoshi_2020_Pediatr.Surg.Int_36_49DPP4 inhibitor reinforces cell junction proteins in mouse model of short bowel syndrome
Sultana_2020_Mol.Ther.Methods.Clin.Dev_17_622Optimization of 5' Untranslated Region of Modified mRNA for Use in Cardiac or Hepatic Ischemic Injury
Suman_2020_Biomarkers__1Toxicity and biomarkers of micro-plastic in aquatic environment: A review
Sun_2020_Anal.Bioanal.Chem_412_6939Ultrasensitive split-type electrochemical sensing platform for sensitive determination of organophosphorus pesticides based on MnO(2) nanoflower-electron mediator as a signal transduction system
Sun_2020_Biochem.Biophys.Res.Commun__PTUPB ameliorates high-fat diet-induced non-alcoholic fatty liver disease via inhibiting NLRP3 inflammasome activation in mice
Sun_2020_Bioorg.Chem_96_103637Protostane-type triterpenoids as natural soluble epoxide hydrolase inhibitors: Inhibition potentials and molecular dynamics
Sun_2020_Bioorg.Chem_97_103680A novel 15-spiro diterpenoid dimer from Andrographis paniculata with inhibitory potential against human carboxylesterase 2
Sun_2020_ChemSusChem_13_6523Tailoring Particle-Enzyme Nanoconjugates for Biocatalysis at the Organic-Organic Interface
Sun_2020_Front.Microbiol_11_1866Whole-Genome Sequencing and Bioinformatics Analysis of Apiotrichum mycotoxinivorans: Predicting Putative Zearalenone-Degradation Enzymes
Sun_2020_Gene_723_143986MicroRNA-544 attenuates diabetic renal injury via suppressing glomerulosclerosis and inflammation by targeting FASN
Sun_2020_J.Appl.Microbiol__Biology and applications of Clonostachys rosea
Sun_2020_J.Clin.Endocrinol.Metab_105_e4831Sexually Dimorphic Crosstalk at the Maternal-Fetal Interface
Sun_2020_J.Int.Med.Res_48_300060520936177Dl-3-n-butylphthalide regulates cholinergic dysfunction in chronic cerebral hypoperfusion rats
Sun_2020_Mar.Pollut.Bull_160_111556Biomonitoring of polycyclic aromatic hydrocarbons (PAHs) from Manila clam Ruditapes philippinarum in Laizhou, Rushan and Jiaozhou, bays of China, and investigation of its relationship with human carcinogenic risk
Sun_2020_Mini.Rev.Med.Chem_20_1709The Research Progress of DPP-4 Inhibitors
Sun_2020_Molecules_25_A Pharmacokinetic and Pharmacodynamic Evaluation of the Anti-Hepatocellular Carcinoma Compound 4-N-Carbobenzoxy-gemcitabine (Cbz-dFdC)
Sun_2020_Nat.Commun_11_1264Divergent receptor proteins confer responses to different karrikins in two ephemeral weeds
Sun_2020_Proteomics.Clin.Appl_14_e1900080Proteomic Analysis Reveals that EPHX1 Contributes to 5-Fluorouracil Resistance in a Human Hepatocellular Carcinoma Cell Line
Sun_2020_Sci.Total.Environ_711_134810Adipogenic activity of 2-ethylhexyl diphenyl phosphate via peroxisome proliferator-activated receptor gamma pathway
Sun_2020_Sci.Total.Environ_745_141140Hydroxylated polychlorinated biphenyls (OH-PCBs) exert strong inhibitory effects towards human carboxylesterases (CESs)
Sun_2020_Toxicol.Appl.Pharmacol__115032Irinotecan-mediated diarrhea is mainly correlated with intestinal exposure to SN-38: Critical role of gut Ugt
Supasai_2020_Eur.J.Pharmacol__173538Acute administration of diazepam or midazolam minimally alters long-term neuropathological effects in the rat brain following acute intoxication with diisopropylfluorophosphate
Suski_2020_Mol.Immunol_127_193Decrease of the pro-inflammatory M1-like response by inhibition of dipeptidyl peptidases 8/9 in THP-1 macrophages - quantitative proteomics of the proteome and secretome
Sussman_2020_Neuropharmacol__108265Computational studies on cholinesterases: Strengthening our understanding of the integration of structure, dynamics and function
Sut_2020_Food.Res.Int_129_108877Ricinodendronheudelotii(Baill.) Heckelstem barks and seed extracts, a native food plant from Africa: Characterization by NMR and HPLC-DAD-ESI-MS(n)
Sut_2020_Molecules_25_Hairy Garlic (Allium subhirsutum) from Sicily (Italy): LC-DAD-MS(n) Analysis of Secondary Metabolites and In Vitro Biological Properties
Suttisansanee_2020_Molecules_25_Mulberry Fruit Cultivar 'Chiang Mai' Prevents Beta-Amyloid Toxicity in PC12 Neuronal Cells and in a Drosophila Model of Alzheimer's Disease
Suzuki_2020_J.Anesth_34_723History of the development of antagonists for neuromuscular blocking agents
Swarbrick_2020_Prog.Lipid.Res_79_101036Structure, function, and regulation of thioesterases
Swissa_2020_Neurotoxicol__Midazolam and isoflurane combination reduces late brain damage in the paraoxon-induced status epilepticus rat model
Syal_2020_Theranostics_10_6337Dysregulated expression of monoacylglycerol lipase is a marker for anti-diabetic drug metformin-targeted therapy to correct impaired neurogenesis and spatial memory in Alzheimer's disease
Sychev_2020_Drug.Metab.Pers.Ther_35_Effect of CES1 and ABCB1 genotypes on the pharmacokinetics and clinical outcomes of dabigatran etexilate in patients with atrial fibrillation and chronic kidney disease
Sylvetsky_2020_Sci.Rep_10_9218Toward Simple, Predictive Understanding of Protein-Ligand Interactions: Electronic Structure Calculations on Torpedo Californica Acetylcholinesterase Join Forces with the Chemist's Intuition
Szalaj_2020_J.Enzyme.Inhib.Med.Chem_35_1944Multidirectional in vitro and in cellulo studies as a tool for identification of multi-target-directed ligands aiming at symptoms and causes of Alzheimer's disease
Szaloki_2020_Molecules_25_[1,5]-Hydride Shift-Cyclization versus C(sp(2))-H Functionalization in the Knoevenagel-Cyclization Domino Reactions of 1,4- and 1,5-Benzoxazepines
Taabazuing_2020_Immunol.Rev_297_13The NLRP1 and CARD8 inflammasomes
Tabassum_2020_Environ.Sci.Pollut.Res.Int_27_35837Potential attenuation of biochemical parameters and enzymatic functions in Cyprinus carpio fingerlings by Phenthoate 50 EC insecticide exposure
Tacin_2020_Prep.Biochem.Biotechnol__1Microbial lipase: a new approach for a heterogeneous biocatalyst
Tahmasebi_2020_Bioorg.Chem_105_104351Design, synthesis and biological evaluation of anticholinesterase peptides: Fragment-based vs. template-based peptide design
Tak_2020_ACS.Chem.Neurosci_11_3741Clitoria ternatea Mediated Synthesis of Graphene Quantum Dots for the Treatment of Alzheimer's Disease
Takahashi_2020_Chirality_32_73Investigation of the chiral recognition ability of human carboxylesterase 1 using indomethacin esters
Takahashi_2020_Eur.J.Pharm.Sci__105455Design, synthesis and biological evaluation of water-soluble phenytoin prodrugs considering the substrate recognition ability of human carboxylesterase 1
Takahashi_2020_Surg.Case.Rep_6_74Gastric volvulus with perforation 1 year after total pancreatectomy: a case report
Takaki_2020_Mol.Clin.Oncol_12_60High cholinesterase predicts tolerance to sorafenib treatment and improved prognosis in patients with transarterial chemoembolization refractory intermediate stage hepatocellular carcinoma
Takeo_2020_Anal.Chem_92_12379Mass Spectrometric Enzyme Histochemistry Method Developed for Visualizing In Situ Cholinesterase Activity in Mus musculus and Drosophila melanogaster
Takomthong_2020_Biomedicines_8_Structure-Activity Analysis and Molecular Docking Studies of Coumarins from Toddalia asiatica as Multifunctional Agents for Alzheimer's Disease
Talbott_2020_Sci.Rep_10_11287Formation and characterization of lipid droplets of the bovine corpus luteum
Talebreza_2020_Med.Clin.North.Am_104_405Recognizing and Managing Polypharmacy in Advanced Illness
Taler-Vercic_2020_Molecules_25_The Structure and Function of Paraoxonase-1 and Its Comparison to Paraoxonase-2 and -3
Tallat_2020_J.Genet.Eng.Biotechnol_18_10Caspases as prognostic markers and mortality predictors in acute organophosphorus poisoning
Talley_2020_Chem.Res.Toxicol_33_2455Inhibition of Acetylcholinesterases by Stereoisomeric Organophosphorus Compounds Containing Both Thioester and p-Nitrophenyl Leaving Groups
Talwar_2020_Sci.Rep_10_1151Defining the Environmental Adaptations of Genus Devosia: Insights into its Expansive Short Peptide Transport System and Positively Selected Genes
Tam_2020_Chem.Biol.Drug.Des_95_205Efficacy of chalcone and xanthine derivatives on lipase inhibition: A systematic review
Tamfu_2020_Foods_9_Antibiofilm and Enzyme Inhibitory Potentials of Two Annonaceous Food Spices, African Pepper (Xylopia aethiopica) and African Nutmeg (Monodora myristica)
Tampio_2020_Mol.Neurobiol_57_4563Targeting of Perforin Inhibitor into the Brain Parenchyma Via a Prodrug Approach Can Decrease Oxidative Stress and Neuroinflammation and Improve Cell Survival
Tan_2020_Am.J.Geriatr.Psychiatry_28_108Do Acetylcholinesterase Inhibitors Prevent or Delay Psychotropic Prescribing in People With Dementia? Analyses of the Swedish Dementia Registry
Tandonnet_2020_Parasit.Vectors_13_562Molecular basis of resistance to organophosphate insecticides in the New World screw-worm fly
Tang_2020_Anal.Chim.Acta_1136_72Multicolor nitrogen dots for rapid detection of thiram and chlorpyrifos in fruit and vegetable samples
Tang_2020_EBioMedicine_53_102696Enhanced monoacylglycerol lipolysis by ABHD6 promotes NSCLC pathogenesis
Tang_2020_Insect.Mol.Biol_29_511Adipokinetic hormone enhances CarE-mediated chlorpyrifos resistance in the brown planthopper, Nilaparvata lugens
Tang_2020_J.Agric.Food.Chem__Functional Characterization of an alpha-Esterase Gene Associated with Malathion Detoxification in Bradysia odoriphaga
Tang_2020_J.Nat.Prod_83_2287Pancreatic Lipase Inhibitory Cyclohexapeptides from the Marine Sponge-Derived Fungus Aspergillus sp. 151304
Tang_2020_J.Nat.Prod_83_473Discovery and Characterization of a PKS-NRPS Hybrid in Aspergillus terreus by Genome Mining
Tang_2020_Mikrochim.Acta_187_450Rolling circle amplification promoted magneto-controlled photoelectrochemical biosensor for organophosphorus pesticides based on dissolution of core-shell MnO(2) nanoflower@CdS mediated by butyrylcholinesterase
Tang_2020_New.Phytol_228_1880GDSL lipase occluded stomatal pore 1 is required for wax biosynthesis and stomatal cuticular ledge formation
Tanzi_2020_Molecules_25_Developing a Library of Mannose-Based Mono- and Disaccharides: A General Chemoenzymatic Approach to Monohydroxylated Building Blocks
Tao_2020_J.Int.Med.Res_48_300060520977392Clinical characteristics and treatment of mixed-pesticide poisoning in a patient: reflections on a particular case
Tao_2020_Reprod.Fertil.Dev_32_967Characteristics of lipid droplets and the expression of proteins involved in lipolysis in the murine cervix during mid-pregnancy
Taslimi_2020_Arch.Pharm.(Weinheim)__e2000210In vitro inhibitory effects of some acetophenone derivatives on some metabolic enzymes and molecular docking
Taslimi_2020_Bioorg.Chem_97_103647Cholinesterases, alpha-glycosidase, and carbonic anhydrase inhibition properties of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives: Synthetic analogues for the treatment of Alzheimer's disease and diabetes mellitus
Taslimi_2020_J.Biomol.Struct.Dyn__1Benzenesulfonamide derivatives as potent acetylcholinesterase, alpha-glycosidase, and glutathione S-transferase inhibitors: biological evaluation and molecular docking studies
Taslimi_2020_J.Biomol.Struct.Dyn__2Biological effects and molecular docking studies of Catechin 5-O-gallate: antioxidant, anticholinergics, antiepileptic and antidiabetic potentials
Taslimi_2020_J.Biomol.Struct.Dyn__3Metal contained Phthalocyanines with 3,4-Dimethoxyphenethoxy substituents: their anticancer, antibacterial activities and their inhibitory effects on some metabolic enzymes with molecular docking studies
Tavares_2020_Medicines.(Basel)_7_Uncharted Source of Medicinal Products: The Case of the Hedychium Genus
Taviano_2020_Biology.(Basel)_9_Cytotoxic, Antioxidant, and Enzyme Inhibitory Properties of the Traditional Medicinal Plant Matthiola incana (L.) R. Br
Tay_2020_J.Clin.Neurosci_72_468Congenital myasthenic syndrome with novel pathogenic variants in the COLQ gene associated with the presence of antibodies to acetylcholine receptors
Taylor_2020_Biol.Psychiatry__The Role of Synaptic Cell Adhesion Molecules and Associated Scaffolding Proteins in Social Affiliative Behaviors
Teajaroen_2020_Toxins.(Basel)_12_A Role of Newly Found Auxiliary Site in Phospholipase A(1) from Thai Banded Tiger Wasp (Vespa affinis) in Its Enzymatic Enhancement: In Silico Homology Modeling and Molecular Dynamics Insights
Tedla_2020_Vaccines.(Basel)_8_Vaccination with Schistosoma mansoni Cholinesterases Reduces the Parasite Burden and Egg Viability in a Mouse Model of Schistosomiasis
Teixeira_2020_Psychopharmacology.(Berl)_237_811Inosine protects against impairment of memory induced by experimental model of Alzheimer disease: a nucleoside with multitarget brain actions
Tel-Cayan_2020_Int.J.Biol.Macromol_165_2395Isolation, structural characterization, and biological activities of galactomannans from Rhizopogon luteolus and Ganoderma adspersum mushrooms
Tellez-Arreola_2020_Mol.Cell.Neurosci__103528MCTP-1 modulates neurotransmitter release in C. elegans
Temeyer_2020_J.Med.Entomol__Association of Salivary Cholinesterase With Arthropod Vectors of Disease
Temitayo_2020_Anat.Cell.Biol_53_342Inhibitory potentials of Cymbopogon citratus oil against aluminium-induced behavioral deficits and neuropathology in rats
Temme_2020_Environ.Sci.Process.Impacts__Diverse dechlorinators and dechlorination genes enriched through amendment of chlorinated natural organic matter fractions
Temviriyanukul_2020_Molecules_25_2600Comparison of Phytochemicals, Antioxidant, and In Vitro Anti-Alzheimer Properties of Twenty-Seven Morus spp. Cultivated in Thailand
Temviriyanukul_2020_Molecules_25_3713The Effect of Sacred Lotus (Nelumbo nucifera) and Its Mixtures on Phenolic Profiles, Antioxidant Activities, and Inhibitions of the Key Enzymes Relevant to Alzheimer's Disease
Tesei_2020_Sci.Rep_10_9770Shotgun proteomics reveals putative polyesterases in the secretome of the rock-inhabiting fungus Knufia chersonesos
Thanomsit_2020_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__108837Acetylcholinesterase (AChE) polyclonal antibody from hybrid catfish (C. macrocephalus x C. gariepinus): Specification, sensitivity and cross reactivity
Thanomsit_2020_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__108956Acetylcholinesterase (AChE) monoclonal antibody generation and validation for use as a biomarker of glyphosate-based herbicide exposure in commercial freshwater fish
Thapak_2020_Curr.Neurovasc.Res__Pharmacological inhibition of Transient Receptor Potential Melastatin 2 (TRPM2) Channels Attenuates Diabetes-induced Cognitive Deficits in Rats: A Mechanistic Study
Thapak_2020_Neurochem.Int__104783Amelioration of diabetes-induced cognitive impairment by Transient Receptor Potential Vanilloid 2 (TRPV2) channel inhibitor: Behavioral and mechanistic study
Tharamak_2020_Pest.Manag.Sci_76_928Synthesis of thymyl esters and their insecticidal activity against Spodoptera litura (Lepidoptera: Noctuidae)
Thawai_2020_Sci.Rep_10_11058A novel diterpene agent isolated from Microbispora hainanensis strain CSR-4 and its in vitro and in silico inhibition effects on acetylcholine esterase enzyme
Thayumanavan_2020_Int.J.Biol.Macromol__Inhibition of glutathione and s-allyl glutathione on pancreatic lipase: Analysis through in vitro kinetics, fluorescence spectroscopy and in silico docking
Therkorn_2020_Mil.Med__Review of Biomarkers and Analytical Methods for Organophosphate Pesticides and Applicability to Nerve Agents
Thielman_2020_J.Org.Chem_85_3812Stereoselective Synthesis of Baulamycin A
Thimm_2020_J.Peripher.Nerv.Syst__Genotype-phenotype correlation in a novel ABHD12 mutation underlying PHARC syndrome
Thomas_2020_Antibiotics.(Basel)_9_307Influence of Single Nucleotide Polymorphisms on Rifampin Pharmacokinetics in Tuberculosis Patients
Thomas_2020_Biomed.Pharmacother_129_110456Peripheral deficiency and antiallodynic effects of 2-arachidonoyl glycerol in a mouse model of paclitaxel-induced neuropathic pain
Thomas_2020_JMIR.Res.Protoc_9_e17603An Ecologically Valid, Longitudinal, and Unbiased Assessment of Treatment Efficacy in Alzheimer Disease (the EVALUATE-AD Trial): Proof-of-Concept Study
Thompson_2020_J.Pharmacol.Exp.Ther_373_230The Endocannabinoid System Alleviates Pain in a Murine Model of Cancer-Induced Bone Pain
Thompson_2020_Neurobiol.Dis_133_104455Positron emission tomography studies of organophosphate chemical threats and oxime countermeasures
Thorn_2020_J.Control.Release_319_168Bacterial lipase triggers the release of antibiotics from digestible liquid crystal nanoparticles
Thukham-Mee_2020_Oxid.Med.Cell.Longev_2020_6123759Effect of Single Administration of Mulberry Milk on the Cognitive Function of 6-12-Year-Old Children: Results from a Randomized, Placebo-Controlled, Crossover Study
Tian_2020_Front.Pharmacol_11_572659Phytochemical Analysis, Antioxidant, Antibacterial, Cytotoxic, and Enzyme Inhibitory Activities of Hedychium flavum Rhizome
Tobias_2020_J.Pediatr.Intensive.Care_9_162Sugammadex: Applications in Pediatric Critical Care
Todd_2020_Neuropharmacol__108271Gestational exposures to organophosphorus insecticides: From acute poisoning to developmental neurotoxicity
Togioka_2020_Br.J.Anaesth__Randomised controlled trial of sugammadex or neostigmine for reversal of neuromuscular block on the incidence of pulmonary complications in older adults undergoing prolonged surgery
Toker_2020_Chem.Biol.Interact__109007Polyproline-rich peptides associated with Torpedo californica acetylcholinesterase tetramers
Toledo_2021_Biorxiv__MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior
Tomassini_2020_Nat.Prod.Res__1Phytochemical analysis of Viburnum davidii Franch. and cholinesterase inhibitory activity of its dihydrochalcones
Tomke_2020_Bioprocess.Biosyst.Eng__Lipase-catalyzed synthesis of propyl-phenyl acetate: a kinetic and thermodynamic study
Tong_2020_Front.Pharmacol_11_580069Neuroprotective Studies on Polygonum hydropiper L. Essential Oils Using Transgenic Animal Models
Topcu_2020_Curr.Alzheimer.Res__Anticholinesterase and Antioxidant Activities of Natural Abietane Diterpenoids with Molecular Docking Studies
Tormet-Gonzalez_2020_Acta.Crystallogr.D.Struct.Biol_76_868An epoxide hydrolase from endophytic Streptomyces shows unique structural features and wide biocatalytic activity
Torner_2020_Vet.Sci_7_Clinical and Pathological Data of 17 Non-Epithelial Pancreatic Tumors in Cats
Torok_2020_J.Histochem.Cytochem__22155420942213Post-diaminobenzidine Treatments for Double Stainings: Extension of Sulfide-Silver-Gold Intensification for Light and Fluorescent Microscopy
Toschi_2020_BMC.Vet.Res_16_289Thymol modulates the endocannabinoid system and gut chemosensing of weaning pigs
Toublet_2020_Eur.J.Med.Chem_210_113059Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT(6) receptor antagonist with therapeutic interest in Alzheimer's disease
Tournier_2020_Nature_580_216An engineered PET depolymerase to break down and recycle plastic bottles
Traini_2020_J.Alzheimers.Dis_76_317Volume Analysis of Brain Cognitive Areas in Alzheimer's Disease: Interim 3-Year Results from the ASCOMALVA Trial
Tran_2020_Molecules_25_3644Design of Curcumin and Flavonoid Derivatives with Acetylcholinesterase and Beta-Secretase Inhibitory Activities Using in Silico Approaches
Tran_2020_Molecules_25_3916Synthesis, In Silico and In Vitro Evaluation for Acetylcholinesterase and BACE-1 Inhibitory Activity of Some N-Substituted-4-Phenothiazine-Chalcones
Tran_2020_Molecules_25_4064Synthesis, In Silico and In Vitro Evaluation of Some Flavone Derivatives for Acetylcholinesterase and BACE-1 Inhibitory Activity
Trendafilova_2020_Chem.Biodivers__Caffeoylquinic Acids, Cytotoxic, Antioxidant, Acetylcholinesterase and Tyrosinase Enzyme Inhibitory Activities of Six Inula Species from Bulgaria
Trestrail_2020_Sci.Total.Environ_705_135826Foaming at the mouth: Ingestion of floral foam microplastics by aquatic animals
Triantafyllou_2020_Acta.Histochem__151540Organic secretion in ductal cells of the sublingual salivary gland of ferret: Histochemical observations
Trigueiro-Louro_2020_Comput.Struct.Biotechnol.J_18_2117Unlocking COVID therapeutic targets: A structure-based rationale against SARS-CoV-2, SARS-CoV and MERS-CoV Spike
Trindade-da-Silva_2020_FASEB.J__Soluble epoxide hydrolase inhibitor, TPPU, increases regulatory T cells pathway in an arthritis model
Tripathi_2020_Arch.Pharm.(Weinheim)__e2000036Exploration of dual fatty acid amide hydrolase and cholinesterase inhibitory potential of some 3-hydroxy-3-phenacyloxindole analogs
Tripathi_2020_J.Comput.Aided.Mol.Des__Computational exploration and experimental validation to identify a dual inhibitor of cholinesterase and amyloid-beta for the treatment of Alzheimer's disease
Trobec_2020_Biomed.Pharmacother_127_110161Structural and functional characterization of an organometallic ruthenium complex as a potential myorelaxant drug
Trobiani_2020_Neurosci.Biobehav.Rev_119_37The neuroligins and the synaptic pathway in Autism Spectrum Disorder
Troselj_2020_Microbiology__Conditional requirement of SglT for type IV pili function and S-motility in Myxococcus xanthus
Trujillo-Chacon_2020_Phytochem.Anal_31_46In vitro micropropagation and alkaloids analysis by GC-MS of Chilean Amaryllidaceae plants: Rhodophiala pratensis
Tsai_2020_J.Vet.Intern.Med_34_258Congenital myasthenic syndrome in Golden Retrievers is associated with a novel COLQ mutation
Tsarpali_2020_Sci.Total.Environ_711_135101Assessing the seasonal and intrinsic variability of neurotoxic and cyto-genotoxic biomarkers in blood of free-living Eleonoras' falcons
Tseng_2020_Polymers.(Basel)_12_Synthesis, Physical Properties and Enzymatic Degradation of Biodegradable Nanocomposites Fabricated Using Poly(Butylene Carbonate-Co-Terephthalate) and Organically Modified Layered Zinc Phenylphosphonate
Tsugama_2020_Biochem.Biophys.Res.Commun__A GDSL-type esterase/lipase gene, GELP77, is necessary for pollen dissociation and fertility in Arabidopsis
Tsugoshi_2020_Chem.Biol.Interact__109148Inhibitory effects of organophosphate esters on carboxylesterase activity of rat liver microsomes
Tsukimi_2020_Neurogastroenterol.Motil__e13866Effects and sites of action of a M1 receptor positive allosteric modulator on colonic motility in rats and dogs compared with 5-HT4 agonism and cholinesterase inhibition
TuGrak_2020_Turk.J.Chem_44_1601Synthesis and pharmacological effects of novel benzenesulfonamides carrying benzamide moiety as carbonic anhydrase and acetylcholinesterase inhibitors
Tu_2020_Nat.Commun_11_971Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis
Tuan_2020_J.Phys.Chem.B__Unraveling the Structural Dynamics of an Enzyme Encapsulated within a Metal-Organic Framework
Tugrak_2020_Arch.Pharm.(Weinheim)__e2000375Synthesis and in vitro carbonic anhydrases and acetylcholinesterase inhibitory activities of novel imidazolinone-based benzenesulfonamides
Tunali_2020_J.Food.Biochem__e13382The effects of chard on brain damage in valproic acid-induced toxicity
Tundis_2020_Molecules_25_Salvia officinalis L. from Italy: A Comparative Chemical and Biological Study of Its Essential Oil in the Mediterranean Context
Turhan_2020_Arch.Pharm.(Weinheim)__e2000030Novel benzo[b]xanthene derivatives: Bismuth(III) triflate-catalyzed one-pot synthesis, characterization, and acetylcholinesterase, glutathione S-transferase, and butyrylcholinesterase inhibitory properties
Turja_2020_Environ.Sci.Pollut.Res.Int__Biomarker responses and accumulation of polycyclic aromatic hydrocarbons in Mytilus trossulus and Gammarus oceanicus during exposure to crude oil
Turkez_2020_Biomolecules_10_Histidyl-Proline Diketopiperazine Isomers as Multipotent Anti-Alzheimer Drug Candidates
Turkiewicz_2020_Antioxidants.(Basel)_9_ABTS On-Line Antioxidant, alpha-Amylase, alpha-Glucosidase, Pancreatic Lipase, Acetyl- and Butyrylcholinesterase Inhibition Activity of Chaenomeles Fruits Determined by Polyphenols and other Chemical Compounds
Turkiewicz_2020_Food.Chem_323_126830The influence of different carrier agents and drying techniques on physical and chemical characterization of Japanese quince (Chaenomeles japonica) microencapsulation powder
Tvina_2020_Eur.J.Med.Genet__103881Prenatal and postnatal phenotype of a pathologic variant in the ATP6AP1 gene
Tyukhtenko_2020_Sci.Rep_10_18531Conformational gating, dynamics and allostery in human monoacylglycerol lipase
Ubaid_2020_Sci.Total.Environ_755_142649A comprehensive review on chlorpyrifos toxicity with special reference to endocrine disruption: Evidence of mechanisms, exposures and mitigation strategies
Uchida_2020_Micromachines.(Basel)_11_Thread- and Capillary Tube-Based Electrodes for the Detection of Glucose and Acetylthiocholine
Uchigashima_2020_Elife_9_Specific Neuroligin3-alphaNeurexin1 signaling regulates GABAergic synaptic function in mouse hippocampus
Uchigashima_2020_J.Biol.Chem__Neuroligin3 splice isoforms shape inhibitory synaptic function in the mouse hippocampus
Uckun_2020_Drug.Chem.Toxicol__1Evaluation of the acute toxic effect of azoxystrobin on non-target crayfish (Astacus leptodactylus Eschscholtz, 1823) by using oxidative stress enzymes, ATPases and cholinesterase as biomarkers
Uddin_2020_Curr.Pharm.Des__Exploring the Multifunctional Neuroprotective Promise of Rasagiline Derivatives for Multi-Dysfunctional Alzheimer's Disease
Uddin_2020_J.Pharm.Pharmacol__TV 3326 for Alzheimer's dementia: a novel multimodal ChE and MAO inhibitors to mitigate Alzheimer's-like neuropathology
Uddin_2020_Molecules_25_1267Molecular Insight into the Therapeutic Promise of Flavonoids against Alzheimer's Disease
Uddin_2020_Molecules_25_5011Evaluation of Cholinesterase Inhibitory Potential of Different Genotypes of Ziziphus nummularia, Their HPLC-UV, and Molecular Docking Analysis
Ueta_2020_iScience_23_101385DOK7 Gene Therapy Enhances Neuromuscular Junction Innervation and Motor Function in Aged Mice
Ullah_2020_Pharmaceuticals.(Basel)_13_Attenuation of Spatial Memory in 5xFAD Mice by Halting Cholinesterases, Oxidative Stress and Neuroinflammation Using a Cyclopentanone Derivative
Umezawa_2020_PLoS.One_15_e0243984Transcriptome analysis of the brown rot fungus Gloeophyllum trabeum during lignocellulose degradation
Umukoro_2020_Drug.Metab.Pers.Ther_35_Protective effect of Cyperus esculentus (tiger nut) extract against scopolamine-induced memory loss and oxidative stress in mouse brain
Underlin_2020_Front.Bioeng.Biotechnol_8_332Feruloyl Esterases for Biorefineries: Subfamily Classified Specificity for Natural Substrates
Unugul_2020_J.Air.Waste.Manag.Assoc_70_1198Environmentally friendly processes from coffee wastes to trimethylolpropane esters to be considered biolubricants
Upadhyay_2020_Metab.Brain.Dis__Neuroprotective effect of Reinwardtia indica against scopolamine induced memory-impairment in rat by attenuating oxidative stress
Urabe_2020_Eur.J.Med.Chem_203_112521Discovery of MGS0274, an ester prodrug of a metabotropic glutamate receptor 2/3 agonist with improved oral bioavailability
Urata_2020_Life.(Basel)_10_Fatty Liver, and Not Visceral Fat, Is More Associated with Liver Fibrosis and Diabetes in Non-Obese Japanese Individuals: A Cross-Sectional Study
Urban-Malinga_2020_Chemosphere__128685Do the graphene nanoflakes pose a potential threat to the polychaete Hediste diversicolor?
Urban_2020_J.Pediatr.Urol_16_20Mucosectomy disrupting the enteric nervous system causes contraction and shrinkage of gastrointestinal flaps: potential implications for augmentation cystoplasty
Urbanek_2020_Biochim.Biophys.Acta.Proteins.Proteom_1868_140315Biochemical properties and biotechnological applications of microbial enzymes involved in the degradation of polyester-type plastics
Vaci_2020_Br.J.Psychiatry__1Real-world effectiveness, its predictors and onset of action of cholinesterase inhibitors and memantine in dementia: retrospective health record study
Vahedi-Mazdabadi_2020_Iran.J.Pharm.Res_19_216Anti-cholinesterase and Neuroprotective Activities of Sweet and Bitter Apricot Kernels (Prunus armeniaca L.)
Vahidi_2020_J.Food.Sci.Technol__1An organic solvent-tolerant lipase of Streptomyces pratensis MV1 with the potential application for enzymatic improvement of n6/n3 ratio in polyunsaturated fatty acids from fenugreek seed oil
Vairinhos_2020_Z.Naturforsch.C.J.Biosci__Essential oils of spontaneous species of the genus Lavandula from Portugal: a brief review
Vaknine_2020_Neuropharmacol_168_108020Central and peripheral anti-inflammatory effects of acetylcholinesterase inhibitors
Van Overloop_2020_Geriatr.Psychol.Neuropsychiatr.Vieil_18_283[Psychotropic drugs use in cognitive behavioral specialized care unit]
Van den Berg_2020_Sci.Total.Environ_731_139150Potential impact of chemical stress on freshwater invertebrates: A sensitivity assessment on continental and national scale based on distribution patterns, biological traits, and relatedness
Vancampfort_2020_J.Am.Med.Dir.Assoc__The Impact of Pharmacologic and Nonpharmacologic Interventions to Improve Physical Health Outcomes in People With Dementia: A Meta-Review of Meta-Analyses of Randomized Controlled Trials
Vanhoutte_2020_J.Med.Chem_63_11845Rapid Solid-Phase Construction of Serine Hydrolase Probes Results in Selective Activity-Based Probes for Acyl Protein Thioesterases-1/2
Vankadari_2020_Emerg.Microbes.Infect_9_601Emerging WuHan (COVID-19) coronavirus: glycan shield and structure prediction of spike glycoprotein and its interaction with human CD26
Varennes_2020_Int.J.Mol.Sci_21_The Metabolism of Epoxyeicosatrienoic Acids by Soluble Epoxide Hydrolase Is Protective against the Development of Vascular Calcification
Varfolomeev_2020_Dokl.Biochem.Biophys_491_85Kinetics of Chemical Processes in the Human Brain. Proton Blockade of Acetylcholinesterase and pH-Impulse in the Mechanism of Functioning of the Cholinergic Synapse
Varfolomeev_2020_Dokl.Biochem.Biophys_492_147Kinetics of Chemical Processes in the Human Brain. The Cholinergic Synapse-Mechanisms of Functioning and Control Methods
Vasina_2020_Methods.Enzymol_643_51Exploration of enzyme diversity: High-throughput techniques for protein production and microscale biochemical characterization
Vasquez_2020_J.Chem.Inf.Model_60_995Rational Design and In Vitro Evaluation of Novel Peptides Binding to Neuroligin-1 for Synaptic Targeting
Veena_2020_Int.J.Med.Mushrooms_22_593Caterpillar Medicinal Mushroom, Cordyceps militaris (Ascomycetes), Mycelia Attenuates Doxorubicin-Induced Oxidative Stress and Upregulates Krebs Cycle Dehydrogenases Activity and ATP Level in Rat Brain
Venkatesan_2020_Curr.Top.Behav.Neurosci_45_47Endogenous Acetylcholine and Its Modulation of Cortical Microcircuits to Enhance Cognition
Venugopala_2020_Molecules_25_Larvicidal Activities of 2-Aryl-2,3-Dihydroquinazolin -4-ones against Malaria Vector Anopheles arabiensis, In Silico ADMET Prediction and Molecular Target Investigation
Verma_2020_Appl.Biochem.Biotechnol__Cloning, Characterization, and Structural Modeling of an Extremophilic Bacterial Lipase Isolated from Saline Habitats of the Thar Desert
Verma_2020_Chronobiol.Int__1Age-dependent altered redox homeostasis in the chronodisrupted rat model and moderation by melatonin administration
Verma_2020_J.Comput.Chem_41_500The Membrane-Integrated Steric Chaperone Lif Facilitates Active Site Opening of Pseudomonas aeruginosa Lipase A
Viana_2020_Environ.Pollut_267_115458How safe are the new green energy resources for marine wildlife? The case of lithium
Viayna_2020_J.Phys.Chem.B_124_28Interplay between Ionization and Tautomerism in Bioactive beta-Enamino Ester-Containing Cyclic Compounds: Study of Annulated 1,2,3,6-Tetrahydroazocine Derivatives
Vickram_2020_Int.J.Biol.Macromol_146_946Human prostasomes an extracellular vesicle - Biomarkers for male infertility and prostrate cancer: The journey from identification to current knowledge
Vidal_2020_Front.Neurosci_14_835Pharmaco-fUS for Characterizing Drugs for Alzheimer's Disease - The Case of THN201, a Drug Combination of Donepezil Plus Mefloquine
Viegas_2020_Sci.Rep_10_3578Structural and dynamic insights revealing how lipase binding domain MD1 of Pseudomonas aeruginosa foldase affects lipase activation
Vieira_2020_Environ.Sci.Pollut.Res.Int__Toxic effects of a mancozeb-containing commercial formulation at environmental relevant concentrations on zebrafish embryonic development
Vieyres_2020_PLoS.Pathog_16_e1008554The ATGL lipase cooperates with ABHD5 to mobilize lipids for hepatitis C virus assembly
Villafana_2020_Ecol.Evol_10_1425Diversity, structure, and synteny of the cutinase gene of Colletotrichum species
Villeda-Gonzalez_2020_Life.Sci__117585Nicotinamide reduces inflammation and oxidative stress via the cholinergic system in fructose-induced metabolic syndrome in rats
Villo_2020_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1865_158553Calorimetric approach for comparison of Angiopoietin-like protein 4 with other pancreatic lipase inhibitors
Virdi_2020_Int.J.Neurosci__1Investigation on Beneficial Role of L-Carnosine in Neuroprotective Mechanism of Ischemic Postconditioning in Mice: Possible role of Histidine Histamine Pathway
Vitorovic-Todorovic_2020_J.Biomol.Struct.Dyn__1Molecular recognition of acetylcholinesterase and its subnanomolar reversible inhibitor: a molecular simulations study
Volkenborn_2020_Microb.Cell.Fact_19_154The length of ribosomal binding site spacer sequence controls the production yield for intracellular and secreted proteins by Bacillus subtilis
Vollmer_2020_Angew.Chem.Int.Ed.Engl_59_15402Beyond Mechanical Recycling: Giving New Life to Plastic Waste
Vouri_2020_J.Am.Geriatr.Soc_68_440Evaluation of the Potential Acetylcholinesterase Inhibitor-Induced Rhinorrhea Prescribing Cascade
Vu_2020_Pestic.Biochem.Physiol_167_104603Voltage-gated chloride channel blocker DIDS as an acaricide for Varroa mites
Vujotic_2020_Arch.Med.Sci_16_811Association between oxidative stress biomarkers and concentrations of some metal ions in the blood of patients with brain tumors and hydrocephalus
Wack_2020_Neurosci.Lett_721_134798Redox regulation of soluble epoxide hydrolase does not affect pain behavior in mice
Wagmann_2020_Front.Chem_8_539How to Study the Metabolism of New Psychoactive Substances for the Purpose of Toxicological Screenings-A Follow-Up Study Comparing Pooled Human Liver S9, HepaRG Cells, and Zebrafish Larvae
Wagner_2020_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1865_158730Lysosomal acid lipase is the major acid retinyl ester hydrolase in cultured human hepatic stellate cells but not essential for retinyl ester degradation
Wagner_2020_Brain.Res_1728_146573Soluble epoxide hydrolase inhibitor mediated analgesia lacks tolerance in rat models
Wagner_2020_Neurotherapeutics_17_900Soluble Epoxide Hydrolase Regulation of Lipid Mediators Limits Pain
Wahid_2020_Phytother.Res__Pharmacological exploration of traditional plants for the treatment of neurodegenerative disorders
Wakabayashi_2020_Planta_251_97CYP722C from Gossypium arboreum catalyzes the conversion of carlactonoic acid to 5-deoxystrigol
Walker_2020_Cancer.Res_80_2045A Protease-Activated Fluorescent Probe Allows Rapid Visualization of Keratinocyte Carcinoma during Excision
Walker_2020_Cells_9_E297Regulation of Synaptic Development by Astrocyte Signaling Factors and Their Emerging Roles in Substance Abuse
Wallace_2020_Environ.Microbiol.Rep_12_578The highly crystalline PET found in plastic water bottles does not support the growth of the PETase-producing bacterium Ideonella sakaiensis
Walther_2020_Small__e2004280Nanozymes and Glucuronides: Glucuronidase, Esterase, and/or Transferase Activity
Wan_2020_Front.Aging.Neurosci_12_532386Association Between Peripheral Adiponectin and Lipids Levels and the Therapeutic Response to Donepezil Treatment in Han Chinese Patients With Alzheimer's Disease
Wan_2020_J.Virol_94_Molecular Mechanism for Antibody-Dependent Enhancement of Coronavirus Entry
Wan_2020_Neuropsychopharmacol.Rep_40_412Lack of rewarding effects of a soluble epoxide hydrolase inhibitor TPPU in mice: Comparison with morphine
Wang_2020_3.Biotech_10_430Characterization of a novel halotolerant esterase from Chromohalobacter canadensis isolated from salt well mine
Wang_2020_ACS.Omega_5_24708Kinetics and Mechanism of Solvent Influence on the Lipase-Catalyzed 1,3-Diolein Synthesis
Wang_2020_ACS.Sens_5_1987Bioluminescent Sensor Reveals that Carboxylesterase 1A is a Novel Endoplasmic Reticulum-Derived Serologic Indicator for Hepatocyte Injury
Wang_2020_Acta.Pharmacol.Sin_41_145Huperzine A ameliorates obesity-related cognitive performance impairments involving neuronal insulin signaling pathway in mice
Wang_2020_Anal.Chem_92_15275A Bioluminescent Probe for Simultaneously Imaging Esterase and Histone Deacetylase Activity in a Tumor
Wang_2020_Biomacromolecules_21_1078Synthesis, Molecular Docking Simulation, and Enzymatic Degradation of AB-Type Indole-Based Polyesters with Improved Thermal Properties
Wang_2020_Biomed.Rep_13_37Neuroprotective effects of the aerial parts of Polygala tenuifolia Willd extract on scopolamine-induced learning and memory impairments in mice
Wang_2020_Biosci.Rep_40_miR-4454 up-regulated by HPV16 E6/E7 promotes invasion and migration by targeting ABHD2/NUDT21 in cervical cancer
Wang_2020_Cell.Res_30_269Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro
Wang_2020_Chem.Commun.(Camb)__Visualization of carboxylesterase 2 with a near-infrared two-photon fluorescent probe and potential evaluation of its anticancer drug effects in an orthotopic colon carcinoma mice model
Wang_2020_Clin.Exp.Pharmacol.Physiol__Donepezil down-regulates propionylation, 2-hydroxyisobutyrylation, butyrylation, succinylation, and crotonylation in the brain of bilateral common carotid artery occlusion-induced vascular dementia rats
Wang_2020_Curr.Med.Res.Opin_36_1107Efficacy and safety of DBPR108 monotherapy in patients with type 2 diabetes: a 12-week, randomized, double-blind, placebo-controlled, phase II clinical trial
Wang_2020_Curr.Vasc.Pharmacol_18_358Rhizoma Coptidis for Alzheimer's Disease and Vascular Dementia: A Literature Review
Wang_2020_Ecol.Evol_10_4816Silicon-mediated multiple interactions: Simultaneous induction of rice defense and inhibition of larval performance and insecticide tolerance of Chilo suppressalis by sodium silicate
Wang_2020_Ecotoxicol.Environ.Saf_203_111046Evaluation of modes of action of pesticides to Daphnia magna based on QSAR, excess toxicity and critical body residues
Wang_2020_Environ.Pollut_267_115397Short-term exposure to norfloxacin induces oxidative stress, neurotoxicity and microbiota alteration in juvenile large yellow croaker Pseudosciaena crocea
Wang_2020_Eur.J.Med.Chem__112915Small molecule therapeutics for tauopathy in Alzheimer's disease: Walking on the path of most resistance
Wang_2020_Food.Funct_11_8680Pentacyclic triterpenoid acids in Styrax as potent and highly specific inhibitors against human carboxylesterase 1A
Wang_2020_Front.Plant.Sci_11_380Hybrid Aspen Expressing a Carbohydrate Esterase Family 5 Acetyl Xylan Esterase Under Control of a Wood-Specific Promoter Shows Improved Saccharification
Wang_2020_Insects_11_Insight into the Functional Diversification of Lipases in the Endoparasitoid Pteromalus puparum (Hymenoptera: Pteromalidae) by Genome-scale Annotation and Expression Analysis
Wang_2020_Int.J.Biol.Macromol_163_1487Identification of genes involved in sex pheromone biosynthesis and metabolic pathway in the Chinese oak silkworm, Antheraea pernyi
Wang_2020_Int.J.Biol.Macromol_60_1189Enhancing the thermostability of Rhizopus chinensis lipase by rational design and MD simulations
Wang_2020_J.Agric.Food.Chem_68_12358Effect of Solvent on Acyl Migration of 2-Monoacylglycerols in Enzymatic Ethanolysis
Wang_2020_J.Am.Chem.Soc_142_8464Molecular Basis for the Biosynthesis of an Unusual Chain-Fused Polyketide Gregatin A
Wang_2020_J.Econ.Entomol_113_911Bemisia tabaci (Hemiptera: Aleyrodidae) Insecticide Resistance in Shandong Province, China
Wang_2020_J.Food.Biochem__e13530The influence of in vitro gastrointestinal digestion on the Perilla frutescens leaf extract: Changes in the active compounds and bioactivities
Wang_2020_J.Ind.Microbiol.Biotechnol_47_1019Engineering of a thermo-alkali-stable lipase from Rhizopus chinensis by rational design of a buried disulfide bond and combinatorial mutagenesis
Wang_2020_J.Insect.Sci_20_Growth Performance and Enzymatic Response of the Grasshopper, Calliptamus abbreviatus (Orthoptera: Acrididae), to Six Plant-Derived Compounds
Wang_2020_J.Nat.Prod__Yanhusanines A-F, Isoquinoline-Derived Alkaloid Enantiomers from Corydalis yanhusuo and Their Biological Activity
Wang_2020_Lett.Appl.Microbiol__Enhancing secretion of polyethylene terephthalate hydrolase PETase in Bacillus subtilis WB600 mediated by the SP(amy) signal peptide
Wang_2020_Medrxiv__An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility
Wang_2020_Mol.Neurobiol__Prolonged Soluble Epoxide Hydrolase Reactivity in Brain Endothelial Cells Is Associated with Long Cognitive Deficits in Sepsis
Wang_2020_Molecules_25_Protective Evaluation of Compounds Extracted from Root of Rhodiola rosea L. against Methylglyoxal-Induced Toxicity in a Neuronal Cell Line
Wang_2020_Nat.Prod.Res__1Secondary metabolites of Galactomyces geotrichum from Laminaria japonica ameliorate cognitive deficits and brain oxidative stress in D-galactose induced Alzheimer's disease mouse model
Wang_2020_Nat.Prod.Res__2A new steroidal alkaloid from Fritillaria michailovskyi Fomin
Wang_2020_Nat.Prod.Res__3A novel streptonigrin type alkaloid from the Streptomyces flocculus CGMCC 4.1223 mutant stnA/Q2
Wang_2020_Nucl.Med.Commun__Effects of nucleo(s)tide analogs therapy on chronic hepatitis B as evaluated by hepatosplenic radionuclide angiography
Wang_2020_Org.Lett_22_8240Scocycamides, a Pair of Macrocyclic Dicaffeoylspermidines with Butyrylcholinesterase Inhibition and Antioxidation Activity from the Roots of Scopolia tangutica
Wang_2020_PLoS.One_15_e0231981Acetylcholinesterase electrochemical biosensors with graphene-transition metal carbides nanocomposites modified for detection of organophosphate pesticides
Wang_2020_Pestic.Biochem.Physiol_163_117Monitoring insecticide resistance and diagnostics of resistance mechanisms in Bemisia tabaci Mediterranean (Q biotype) in China
Wang_2020_Pestic.Biochem.Physiol_170_104704Characterization of a novel hyper-thermostable and chlorpyrifos-hydrolyzing carboxylesterase EstC: A representative of the new esterase family XIX
Wang_2020_Proc.Natl.Acad.Sci.U.S.A_117_8431Soluble epoxide hydrolase is an endogenous regulator of obesity-induced intestinal barrier dysfunction and bacterial translocation
Wang_2020_Prostaglandins.Other.Lipid.Mediat__106449A novel interaction between soluble epoxide hydrolase and the AT1 receptor in retinal microvascular damage
Wang_2020_RSC.Med.Chem_11_225Chromone and donepezil hybrids as new multipotent cholinesterase and monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease
Wang_2020_Support.Care.Cancer_28_581Cancer-related fatigue and biochemical parameters among cancer patients with different stages of sarcopenia
Wang_2020_Toxicon_173_62A case report of acute renal failure caused by Amanita neoovoidea poisoning in Anhui Province, eastern China
Wang_2020_Toxics_8_Mechanisms of Increased Indoxacarb Toxicity in Methoxyfenozide-Resistant Cotton Bollworm Helicoverpa armigera (Lepidoptera: Noctuidae)
Wang_2020_iScience_23_101252OSBPL2 Is Required for the Binding of COPB1 to ATGL and the Regulation of Lipid Droplet Lipolysis
Wang_2021_DNA.Cell.Biol_40_219Transcription Factors ZEB1 and CREB Promote the Transcription of Bovine ABHD5 Gene
Wani_2020_J.Plant.Growth.Regul__Mechanistic Insights into Strigolactone Biosynthesis, Signaling, and Regulation During Plant Growth and Development
Warad_2020_Molecules_25_Synthesis and Spectral Identification of Three Schiff Bases with a 2-(Piperazin-1-yl)-N-(thiophen-2-yl methylene)ethanamine Moiety Acting as Novel Pancreatic Lipase Inhibitors: Thermal, DFT, Antioxidant, Antibacterial, and Molecular Docking Investigations
Warner_2020_Biology.(Basel)_9_Soluble Epoxide Hydrolase Inhibition in Liver Diseases: A Review of Current Research and Knowledge Gaps
Watanabe_2020_Antonie.Van.Leeuwenhoek_113_349Labilibaculum antarcticum sp. nov., a novel facultative anaerobic, psychrotorelant bacterium isolated from marine sediment of Antarctica
Watanabe_2020_Br.J.Clin.Pharmacol_86_2286Safety and pharmacokinetic profiles of MGS0274 besylate (TS-134), a novel metabotropic glutamate 2/3 receptor agonist prodrug, in healthy subjects
Watanabe_2020_Front.Neurol_11_49Primary Progressive Aphasia as a Prodromal State of Dementia With Lewy Bodies: A Case Report
Watt_2020_J.Am.Geriatr.Soc_68_2516Fall-Related Hospitalizations in Nursing Home Residents Co-Prescribed a Cholinesterase Inhibitor and Beta-Blocker
Wattanathorn_2020_Oxid.Med.Cell.Longev_2020_3096826Memory-Enhancing Effect of a Phytosome Containing the Combined Extract of Mulberry Fruit and Ginger in an Animal Model of Ischemic Stroke with Metabolic Syndrome
Wattmo_2020_BMC.Neurol_20_10Cerebro-spinal fluid biomarker levels: phosphorylated tau (T) and total tau (N) as markers for rate of progression in Alzheimer's disease
Wei_2020_Circ.Res_127_249Endothelial Palmitoylation Cycling Coordinates Vessel Remodeling in Peripheral Artery Disease
Wei_2020_Food.Sci.Nutr_8_1162The cross-sectional study of hepatic lipase SNPs and plasma lipid levels
Wei_2020_Front.Microbiol_11_562063Discovery of Pyranoviolin A and Its Biosynthetic Gene Cluster in Aspergillus violaceofuscus
Wei_2020_J.Am.Chem.Soc__Sanger's Reagent Sensitized Photocleavage of Amide Bond for Constructing Photocages and Regulation of Biological Functions
Wei_2020_Pest.Manag.Sci_76_1142Overexpression of an alternative allele of carboxyl/choline esterase 4 (CCE04) of Tetranychus urticae is associated with high levels of resistance to the keto-enol acaricide spirodiclofen
Weihs_2020_Anal.Chim.Acta.X_6_100059Experimental determination of the bioluminescence resonance energy transfer (BRET) Frster distances of NanoBRET and red-shifted BRET pairs
Weinberger_2020_Front.Microbiol_11_554High Throughput Screening for New Fungal Polyester Hydrolyzing Enzymes
Weinstein_2020_Bioinformatics_37_123PROSS 2: a new server for the design of stable and highly expressed protein variants
Weir_2020_BMJ.Mil.Health_166_42Nerve agents: emergency preparedness
Wejnerowski_2020_Toxins.(Basel)_12_In Vitro Toxicological Screening of Stable and Senescing Cultures of Aphanizomenon, Planktothrix, and Raphidiopsis
Wen-Xia_2020_Appl.Microbiol.Biotechnol_104_9159Five novel and highly efficient endophytic fungi isolated from Huperzia serrata expressing huperzine A for the treatment of Alzheimer's disease
Wen_2020_J.Bone.Miner.Res_35_2252Runx2 Regulates Mouse Tooth Root Development Via Activation of WNT Inhibitor NOTUM
Wen_2020_Lett.Appl.Microbiol_70_181Enantioconvergent hydrolysis of m-nitrostyrene oxide at an elevated concentration by Phaseolus vulgaris epoxide hydrolase in the organic/aqueous two-phase system
Weng_2020_Medicine.(Baltimore)_99_e23679Therapeutic efficacy and immunoregulatory effect of Qiangji Jianli Capsule for patients with myasthenia gravis: Study protocol for a series of randomized, controlled N-of-1 trials
Werhahn_2020_Reprod.Domest.Anim_55_283Rhodesian Ridgebacks have an increased risk to develop benign prostatic hyperplasia
Whitmore_2020_Toxicol.Lett_321_21Assessment of false transmitters as treatments for nerve agent poisoning
Wicinski_2020_Pharmaceuticals.(Basel)_13_Perspective of SGLT2 Inhibition in Treatment of Conditions Connected to Neuronal Loss: Focus on Alzheimer's Disease and Ischemia-Related Brain Injury
Wierda_2020_Sci.Rep_10_18041The soluble neurexin-1beta ectodomain causes calcium influx and augments dendritic outgrowth and synaptic transmission
Wilhelm_2020_Can.J.Physiol.Pharmacol_98_304Therapeutic potential of selanyl amide derivatives in the in vitro anticholinesterase activity and in in vivo antiamnesic action
Wilkinson_2020_J.Struct.Biol__107496Extracellular alpha/beta-hydrolase from Paenibacillus species shares structural and functional homology to Tobacco Salicylic Acid Binding Protein 2
Wille_2020_BMJ.Mil.Health__Early diagnosis of nerve agent exposure with a mobile test kit and implications for medical countermeasures: a trigger to react
Wilt_2020_Bioorg.Chem_103_104165Development of multitarget inhibitors for the treatment of pain: Design, synthesis, biological evaluation and molecular modeling studies
Winek_2020_Proc.Natl.Acad.Sci.U.S.A_117_32606Transfer RNA fragments replace microRNA regulators of the cholinergic poststroke immune blockade
Wittek_2020_Curr.Biol_30_4254The Transmembrane Proteins M6 and Anakonda Cooperate to Initiate Tricellular Junction Assembly in Epithelia of Drosophila
Woida_2020_Sci.Signal_13_The Vibrio cholerae MARTX toxin silences the inflammatory response to cytoskeletal damage before inducing actin cytoskeleton collapse
Wojdylo_2020_Molecules_25_Sprouts vs. Microgreens as Novel Functional Foods: Variation of Nutritional and Phytochemical Profiles and Their In Vitro Bioactive Properties
Wolff_2020_Fungal.Genet.Biol_139_103378Acurin A, a novel hybrid compound, biosynthesized by individually translated PKS- and NRPS-encoding genes in Aspergillus aculeatus
Wolmarans_2020_Rev.Environ.Contam.Toxicol_252_131Current Status and Future Prognosis of Malaria Vector Control Pesticide Ecotoxicology and Xenopus sp
Won_2020_J.Am.Med.Dir.Assoc__Association Between Acetylcholinesterase Inhibitors and Osteoporotic Fractures in Older Persons With Alzheimer's Disease
Wong_2020_ACS.Appl.Mater.Interfaces_12_33500Shielded alpha-Nucleophile Nanoreactor for Topical Decontamination of Reactive Organophosphate
Wong_2020_Microorganisms_8_Potential Effects of Indole-3-Lactic Acid, a Metabolite of Human Bifidobacteria, on NGF-induced Neurite Outgrowth in PC12 Cells
Woo_2020_Arch.Pharm.Res__Chemical constituents from the roots of Kadsura coccinea with their protein tyrosine phosphatase 1B and acetylcholinesterase inhibitory activities
Worek_2020_Arch.Toxicol_94_2275Organophosphorus compounds and oximes: a critical review
Worek_2020_Molecules_25_In Vitro Interaction of Organophosphono- and Organophosphorothioates with Human Acetylcholinesterase
Wright_2020_Mol.Cell.Proteomics_20_100008Thyroglobulin Interactome Profiling Defines Altered Proteostasis Topology Associated With Thyroid Dyshormonogenesis
Wu_2020_Anal.Chem__Cascade Reaction System Integrating Single-Atom Nanozymes with Abundant Cu Sites for Enhanced Biosensing
Wu_2020_Arch.Toxicol_94_3645An update on T-2 toxin and its modified forms: metabolism, immunotoxicity mechanism, and human exposure assessment
Wu_2020_Biochem.Biophys.Res.Commun__Soluble epoxide hydrolase inhibitor protects against blood-brain barrier dysfunction in a mouse model of type 2 diabetes via the AMPK/HO-1 pathway
Wu_2020_Bioorg.Med.Chem__115324Design, synthesis and biological evaluation of novel carbamates as potential inhibitors of acetylcholinesterase and butyrylcholinesterase
Wu_2020_Biosci.Rep_40_Significant association between the endothelial lipase gene 584C/T polymorphism and coronary artery disease risk
Wu_2020_Chem.Biol.Interact_334_109350Biological evaluation of 7-O-amide hesperetin derivatives as multitarget-directed ligands for the treatment of Alzheimer's disease
Wu_2020_Chem.Sci_11_11285A molecular approach to rationally constructing specific fluorogenic substrates for the detection of acetylcholinesterase activity in live cells, mice brains and tissues
Wu_2020_Circ.Res_127_1112LDL-Cholesterol Reduction by ANGPTL3 Inhibition in Mice Is Dependent on Endothelial Lipase
Wu_2020_Evid.Based.Complement.Alternat.Med_2020_8617143Effects of Malania oleifera Chun Oil on the Improvement of Learning and Memory Function in Mice
Wu_2020_FASEB.J_34_1983Algorithm-based coevolution network identification reveals key functional residues of the alpha/beta hydrolase subfamilies
Wu_2020_FASEB.J_34_8941Solar light induces the release of acetylcholine from skin keratinocytes affecting melanogenesis
Wu_2020_Fish.Shellfish.Immunol_97_204Anti-foodborne enteritis effect of galantamine potentially via acetylcholine anti-inflammatory pathway in fish
Wu_2020_Food.Chem__128661Patatin primary structural properties and effects on lipid metabolism
Wu_2020_Food.Funct_11_10925AGLPM and QMDDQ peptides exert a synergistic action on memory improvement against scopolamine-induced amnesiac mice
Wu_2020_Front.Bioeng.Biotechnol_8_844Effect of a Novel Alpha/Beta Hydrolase Domain Protein on Tolerance of K. marxianus to Lignocellulosic Biomass Derived Inhibitors
Wu_2020_Front.Physiol_11_584405Biological Impact and Enzyme Activities of Spodoptera litura (Lepidoptera: Noctuidae) in Response to Synergistic Action of Matrine and Beauveria brongniartii
Wu_2020_Int.J.Mol.Sci_21_A Network-Based Approach to Explore the Mechanisms of Uncaria Alkaloids in Treating Hypertension and Alleviating Alzheimer's Disease
Wu_2020_J.Agric.Food.Chem__Neuroprotective function of a novel hexapeptide QMDDQ from shrimp via activation of PKA/CREB/BNDF signaling pathway and its structure-activity relationship
Wu_2020_J.Hazard.Mater_403_123619Double-enzymes-mediated Fe(2+)/Fe(3+) conversion as magnetic relaxation switch for pesticide residues sensing
Wu_2020_Medicine.(Baltimore)_99_e22084Left atrial appendage thrombus formation in a patient with atrial fibrillation on dabigatran therapy associated with CES1 and ABCB1 genetic polymorphisms: A case report
Wu_2020_Molecules_25_Novozym 435-Catalyzed Synthesis of Well-Defined Hyperbranched Aliphatic Poly(beta-thioether ester)
Wu_2020_Neurochem.Int_141_104861Solar light induces expression of acetylcholinesterase in skin keratinocytes: Signalling mediated by activator protein 1 transcription factor
Wu_2020_Onco.Targets.Ther_13_2599Fibroblast Activation Protein (FAP) Overexpression Induces Epithelial-Mesenchymal Transition (EMT) in Oral Squamous Cell Carcinoma by Down-Regulating Dipeptidyl Peptidase 9 (DPP9)
Wu_2020_Org.Biomol.Chem__A new fluorescent probe for sensing of biothiols and screening of acetylcholinesterase inhibitors
Wu_2020_Pest.Manag.Sci__Transcriptome analysis of putative detoxification genes in the Asian citrus psyllid, Diaphorina citri
Wu_2020_Pestic.Biochem.Physiol_166_104551Insecticidal activity of triterpenoids and volatile oil from the stems of Tetraena mongolica
Wullich_2020_Appl.Environ.Microbiol__Definition of an alpha/beta-hydrolase fold subfamily comprising Pseudomonas quinolone signal cleaving dioxygenases
Wurm_2020_Alzheimers.Dement.(N.Y)_6_e12014Prescription patterns of antidementives in a high income country: A pharmacoepidemiologic study
Wysocka_2020_Curr.Alzheimer.Res__Dangerous Liaisons: Tau Interaction with Muscarinic Receptors
Xi_2020_Molecules_25_A Novel Purification Procedure for Active Recombinant Human DPP4 and the Inability of DPP4 to Bind SARS-CoV-2
Xia_2020_AMB.Express_10_138Improving the production of AHL lactonase AiiO-AIO6 from Ochrobactrum sp. M231 in intracellular protease-deficient Bacillus subtilis
Xia_2020_DNA.Cell.Biol__miR-2382-5p Regulates Lipid Metabolism by Targeting NDRG2 in Mammary Epithelial Cells of Dairy Cattle
Xiang_2020_J.Asian.Nat.Prod.Res__1Two new 2-phenylethylchromones from artificial agarwood by holing method
Xiang_2020_Nat.Prod.Res__1Three new dimeric 2-(2-phenylethyl)chromones from artificial agarwood of Aquilaria sinensis
Xiao_2020_Front.Bioeng.Biotechnol_8_889Synergistic Degradation of Pyrethroids by the Quorum Sensing-Regulated Carboxylesterase of Bacillus subtilis BSF01
Xiao_2020_Front.Plant.Sci_11_473Cell Wall Polysaccharide-Mediated Cadmium Tolerance Between Two Arabidopsis thaliana Ecotypes
Xiao_2020_Neural.Regen.Res_15_2270Enzyme-digested Colla Corii Asini (E'jiao) prevents hydrogen peroxide-induced cell death and accelerates amyloid beta clearance in neuronal-like PC12 cells
Xie_2020_Curr.Top.Med.Chem_20_4Progress in Target Drug Molecules for Alzheimer's Disease
Xie_2020_Food.Funct_11_8527Discovery of anthocyanins from cranberry extract as pancreatic lipase inhibitors using a combined approach of ultrafiltration, molecular simulation and spectroscopy
Xin_2020_J.Biochem_168_465Long non-coding RNA ABHD11-AS1 boosts gastric cancer development by regulating miR-361-3p/PDPK1 signalling
Xing_2020_Aquat.Toxicol_231_105736Identification, characterization and expression analyses of cholinesterases genes in Yesso scallop (Patinopecten yessoensis) reveal molecular function allocation in responses to ocean acidification
Xing_2020_J.Food.Sci.Technol_57_2669Gene cloning, expression, purification and characterization of a sn-1,3 extracellular lipase from Aspergillus niger GZUF36
Xiong_2020_Arch.Environ.Contam.Toxicol_79_246In Situ Assessment of Donghu Lake China Using Rare Minnow (Gobiocypris rarus)
Xu_2020_Am.J.Physiol.Gastrointest.Liver.Physiol__Hepatocyte-specific Expression of Human Carboxylesterase 2 Attenuates Non-alcoholic Steatohepatitis in Mice
Xu_2020_Appl.Environ.Microbiol__Structure and Catalytic Mechanism of a Pyrethroid Carboxylesterase PytH from Sphingobium faniae JZ-2
Xu_2020_Appl.Microbiol.Biotechnol__Near-perfect kinetic resolution of o-methylphenyl glycidyl ether by RpEH, a novel epoxide hydrolase from Rhodotorula paludigena JNU001 with high stereoselectivity
Xu_2020_Bioorg.Chem_104_104252Cadinane- and drimane-type sesquiterpenoids produced by Paecilomyces sp. TE-540, an endophyte from Nicotiana tabacum L., are acetylcholinesterase inhibitors
Xu_2020_Bioorg.Chem_98_103721Tacrine-hydroxamate derivatives as multitarget-directed ligands for the treatment of Alzheimer's disease: Design, synthesis, and biological evaluation
Xu_2020_Bioorg.Med.Chem.Lett_30_126985Design, synthesis and evaluation of new 4-arylthiazole-2-amine derivatives as acetylcholinesterase inhibitors
Xu_2020_Bioresour.Technol_310_123476Evaluation of the effect of feruloyl esterase-producing Lactobacillus plantarum and cellulase pretreatments on lignocellulosic degradation and cellulose conversion of co-ensiled corn stalk and potato pulp
Xu_2020_Chem.Biodivers_17_e1900600Four New Diterpenoid Alkaloids from The Roots of Aconitum coreanum
Xu_2020_Endocr.Relat.Cancer_27_657FAM172A promotes follicular thyroid carcinogenesis and may be a marker of FTC
Xu_2020_Environ.Pollut_263_114506Biodegradation of phthalate esters by Paracoccus kondratievae BJQ0001 isolated from Jiuqu (Baijiu fermentation starter) and identification of the ester bond hydrolysis enzyme
Xu_2020_Food.Chem_338_128025Discovery and development of a novel short-chain fatty acid ester synthetic biocatalyst under aqueous phase from Monascus purpureus isolated from Baijiu
Xu_2020_Front.Microbiol_11_568716Comparison of Enzyme Secretion and Ferulic Acid Production by Escherichia coli Expressing Different Lactobacillus Feruloyl Esterases
Xu_2020_Front.Pharmacol_11_593982Physiologically-Based Pharmacokinetic-Pharmacodynamics Model Characterizing CYP2C19 Polymorphisms to Predict Clopidogrel Pharmacokinetics and Its Anti-Platelet Aggregation Effect Following Oral Administration to Coronary Artery Disease Patients With or Without Diabetes
Xu_2020_Hepatol.Commun_4_527Hepatocyte-Specific Expression of Human Carboxylesterase 1 Attenuates Diet-Induced Steatohepatitis and Hyperlipidemia in Mice
Xu_2020_Hum.Exp.Toxicol__960327120984220JZL184 protects hippocampal neurons from oxygen-glucose deprivation-induced injury via activating Nrf2/ARE signaling pathway
Xu_2020_Int.J.Biol.Macromol_150_1184Development of a multivalent acetylcholinesterase inhibitor via dynamic combinatorial chemistry
Xu_2020_Int.J.Mol.Sci_21_Pharmacological Mechanisms Underlying the Neuroprotective Effects of Alpinia oxyphylla Miq. on Alzheimer's Disease
Xu_2020_Mar.Drugs_18_Acylated Aminooligosaccharides from the Yellow Sea Streptomyces sp. HO1518 as Both alpha-Glucosidase and Lipase Inhibitors
Xu_2020_Nanomicro.Lett_12_184Tuning Atomically Dispersed Fe Sites in Metal-Organic Frameworks Boosts Peroxidase-Like Activity for Sensitive Biosensing
Xu_2020_Nat.Commun_11_1069The genome evolution and low-phosphorus adaptation in white lupin
Xu_2020_Pestic.Biochem.Physiol_169_104649Transcriptome analysis of Spodoptera litura reveals the molecular mechanism to pyrethroids resistance
Xu_2020_Zhonghua.Gan.Zang.Bing.Za.Zhi_28_573[Correlational study on portal vein thrombosis of liver cirrhosis]
Xuan Duy_2020_Nat.Prod.Res__1Soluble epoxide hydrolase inhibitors from Docynia indica (Wall.) Decne
Xue_2020_Anal.Bioanal.Chem__Construction and application of a high-content analysis for identifying human carboxylesterase 2 inhibitors in living cell system
Xue_2020_Appl.Microbiol.Biotechnol_104_2067Significant improvement of the enantioselectivity of a halohydrin dehalogenase for asymmetric epoxide ring opening reactions by protein engineering
Xue_2020_Enzyme.Microb.Technol_140_109649Computational design of new enzymes for hydrolysis and synthesis of third-generation cephalosporin antibiotics
Yadang_2020_Int.J.Alzheimers.Dis_2020_6372059Scopolamine-Induced Memory Impairment in Mice: Neuroprotective Effects of Carissa edulis (Forssk.) Valh (Apocynaceae) Aqueous Extract
Yamaguchi_2020_Molecules_25_Patterned Superhydrophobic SERS Substrates for Sample Pre-Concentration and Demonstration of Its Utility through Monitoring of Inhibitory Effects of Paraoxon and Carbaryl on AChE
Yamali_2020_Bioorg.Chem_96_103627Synthesis, structure elucidation, and in vitro pharmacological evaluation of novel polyfluoro substituted pyrazoline type sulfonamides as multi-target agents for inhibition of acetylcholinesterase and carbonic anhydrase I and II enzymes
Yamali_2020_Turk.J.Chem_44_1058Synthesis and bioactivities of 1-(4-hydroxyphenyl)-2-((heteroaryl)thio)ethanones as carbonic anhydrase I, II and acetylcholinesterase inhibitors
Yamamoto_2020_Ann.Med.Surg.(Lond)_55_88Hemorrhoidectomy for elderly patients aged 75 years or more, before and after studies
Yamamoto_2020_Biosci.Biotechnol.Biochem_84_1113Concise synthesis of heliolactone, a non-canonical strigolactone isolated from sunflower
Yamamoto_2020_J.Biochem_168_499Molecular characterization of a prolyl endopeptidase from a feather-degrading thermophile Meiothermus ruber H328
Yan_2020_J.Atheroscler.Thromb__Endothelial Lipase Exerts its Anti-Atherogenic Effect through Increased Catabolism of beta-VLDLs
Yan_2020_J.Hazard.Mater_388_122034Perinatal exposure to 2-Ethylhexyl Diphenyl Phosphate (EHDPHP) affected the metabolic homeostasis of male mouse offspring: Unexpected findings help to explain dose- and diet- specific phenomena
Yan_2020_J.Pak.Med.Assoc_70 [Special Issue]_125Effects and mechanisms of scalp acupuncture on learning and memory in mice with lead poisoning
Yan_2020_Microb.Biotechnol__Thermophilic whole-cell degradation of polyethylene terephthalate using engineered Clostridium thermocellum
Yan_2020_Ying.Yong.Sheng.Tai.Xue.Bao_31_3282[Cross-resistance and the underlying mechanisms of clothianidin resistant population of Frankliniella occidentalis to insecticides]
Yang_2020_Adv.Sci.(Weinh)_7_1902906A Novel Targeted and High-Efficiency Nanosystem for Combinational Therapy for Alzheimer's Disease
Yang_2020_Analyst__An enzyme inhibition-based lab-in-a-syringe device for point-of-need determination of pesticides
Yang_2020_Biochem.J_477_985Adipocyte lipolysis: from molecular mechanisms of regulation to disease and therapeutics
Yang_2020_Biosci.Biotechnol.Biochem__1An anti-inflammatory isoflavone from soybean inoculated with a marine fungus Aspergillus terreus C23-3
Yang_2020_Chem.Biodivers_17_e2000055Chemical Composition and Anti-Alzheimer's Disease-related Activities of a Functional Oil from the Edible Seaweed Hizikia fusiforme
Yang_2020_Chem.Biodivers_17_e2000442Design, synthesis and biological evaluation of xanthone derivatives for possible treatment of Alzheimer's disease based on multi-target strategy
Yang_2020_Dose.Response_18_1559325820972205Neuroprotective Effects of Higenamine Against the Alzheimer's Disease Via Amelioration of Cognitive Impairment, Abeta Burden, Apoptosis and Regulation of Akt/GSK3beta Signaling Pathway
Yang_2020_Eur.J.Med.Chem_187_111913Design, synthesis and evaluation of diosgenin carbamate derivatives as multitarget anti-Alzheimer's disease agents
Yang_2020_Front.Bioeng.Biotechnol_8_544058Cell Surface Display of Thermomyces lanuginosus Lipase in Pichia pastoris
Yang_2020_Front.Genet_11_595166Sequencing of Transcriptome and Small RNA Revealed the Xenobiotic Metabolism-Related Genes and Potential Regulatory miRNA in Asian Tramp Snail
Yang_2020_Int.J.Immunopathol.Pharmacol_34_2058738420954941Activation of cholinergic anti-inflammatory pathway involved in therapeutic actions of alpha-mangostin on lipopolysaccharide-induced acute lung injury in rats
Yang_2020_J.Cell.Biochem_121_135RETRACTED Upregulation of acetylcholinesterase caused by downregulation of microRNA-132 is responsible for the development of dementia after ischemic stroke
Yang_2020_J.Enzyme.Inhib.Med.Chem_35_805Synthesis and biological evaluation of 3-arylbenzofuranone derivatives as potential anti-Alzheimer's disease agents
Yang_2020_J.Ethnopharmacol__113323Traditional uses, phytochemistry, pharmacology and toxicological aspects of the genus Hosta (Liliaceae): A comprehensive review
Yang_2020_J.Hazard.Mater_388_122058Toxicity comparison of nano-sized and micron-sized microplastics to Goldfish Carassius auratus Larvae
Yang_2020_J.Med.Entomol__Insecticide Resistance Status of Aedes aegypti (Diptera: Culicidae) in California by Biochemical Assays
Yang_2020_Mol.Med.Rep__Combining antioxidant astaxantin and cholinesterase inhibitor huperzine A boosts neuroprotection
Yang_2020_Molecules_25_Napthrene Compounds from Mycelial Fermentation Products of Marasmius berteroi
Yang_2020_Nanoscale__Simulated revelation of the adsorption behaviours of acetylcholinesterase on charged self-assembled monolayers
Yang_2020_Nat.Commun_11_3812Targeting QKI-7 in vivo restores endothelial cell function in diabetes
Yang_2020_PLoS.One_15_e0235384AOAH remodels arachidonic acid-containing phospholipid pools in a model of interstitial cystitis pain: A MAPP Network study
Yang_2020_Sci.Rep_10_4701Western diet induces severe nonalcoholic steatohepatitis, ductular reaction, and hepatic fibrosis in liver CGI-58 knockout mice
Yang_2020_Spine.(Phila.Pa.1976)_45_E608Extradural Contralateral C7 Nerve Root Transfer in a Cervical Posterior Approach for Treating Spastic Limb Paralysis: A Cadaver Feasibility Study
Yang_2020_Theranostics_10_4749A COX-2/sEH dual inhibitor PTUPB alleviates lipopolysaccharide-induced acute lung injury in mice by inhibiting NLRP3 inflammasome activation
Yao_2020_Biochem.Pharmacol__114142Type 2 diabetes mellitus decreases systemic exposure of clopidogrel active metabolite through upregulation of P-glycoprotein in rats
Yao_2020_J.Exp.Bot_71_1774Perception of karrikins by plants: a continuing enigma
Yao_2020_J.Oleo.Sci_69_43Hydrophilic Glyceryl Ferulates Preparation Catalyzed by Free Lipase B from Candida antartica
Yao_2020_Phytochemistry_180_112514Seladelicatulasine A-G, C(27) steroidal glycosides with cholinesterase inhibitory activities from Selaginella delicatula
Yared_2020_Malar.J_19_180Insecticide resistance in Anopheles stephensi in Somali Region, eastern Ethiopia
Yasuda_2020_Biol.Pharm.Bull_43_616Reduced Serum Cholesterol and Triglyceride Levels in a Choline-Deficient L-Amino Acid-Defined High-Fat Diet (CDAHFD)-Induced Mouse Model of Non-alcoholic Steatohepatitis (NASH)
Yasuda_2020_Biotechnol.Rep.(Amst)_27_e00505Highly efficient preparation of 1-lysophosphatidylcholine via high proportion of Novozym 435 (lipase B from Candida antarctica)-catalyzed ethanolysis
Yaw_2020_J.Wildl.Dis__Postmortem Evaluation of Reintroduced Migratory Whooping Cranes (Grus americana) in Eastern North America
Ye_2020_Int.J.Mol.Sci_21_Neuroprotective Effect of Bean Phosphatidylserine on TMT-Induced Memory Deficits in a Rat Model
Ye_2020_Mikrochim.Acta_187_511A ratiometric fluorescence probe based on graphene quantum dots and o-phenylenediamine for highly sensitive detection of acetylcholinesterase activity
Ye_2020_Trials_21_520Safety and efficacy assessment of allogeneic human dental pulp stem cells to treat patients with severe COVID-19: structured summary of a study protocol for a randomized controlled trial (Phase I / II)
Yekta_2020_Int.J.Biol.Macromol__The inefficacy of donepezil on glycated-AChE inhibition: Binding affinity, complex stability and mechanism
Yener_2020_Food.Chem_327_127045Selective in vitro and in silico enzymes inhibitory activities of phenolic acids and flavonoids of food plants: Relations with oxidative stress
Yeong_2020_Curr.Med.Chem__Repurposing Antihypertensive Drugs for the Management of Alzheimer's Disease
Yerri_2020_Chemistry_26_15035Chemoselective Hydrogenation of 6-Alkynyl-3-fluoro-2-pyridinaldoximes: Access to First-in-Class 6-Alkyl-3-Fluoro-2-pyridinaldoxime Scaffolds as New Reactivators of Sarin-Inhibited Human Acetylcholinesterase with Increased Blood-Brain Barrier Permeability
Yi_2020_Brain.Commun_2_fcaa058M1 muscarinic acetylcholine receptor dysfunction in moderate Alzheimer's disease pathology
Yi_2020_Front.Microbiol_11_522164Symbiotic Fungus Affected the Asian Citrus Psyllid (ACP) Resistance to Imidacloprid and Thiamethoxam
Yiannopoulou_2020_J.Cent.Nerv.Syst.Dis_12_1179573520907397Current and Future Treatments in Alzheimer Disease: An Update
Yin_2020_Appl.Biochem.Biotechnol_191_1670Refolding with Simultaneous Purification of Recombinant Serratia marcescens Lipase by One-Step Ultrasonication Process
Yin_2020_Drug.Des.Devel.Ther_14_1983Activation of Cholinergic Anti-Inflammatory Pathway in Peripheral Immune Cells Involved in Therapeutic Actions of alpha-Mangostin on Collagen-Induced Arthritis in Rats
Yin_2020_Nat.Commun_11_2978ARS2/MAGL signaling in glioblastoma stem cells promotes self-renewal and M2-like polarization of tumor-associated macrophages
Yin_2020_Neural.Plast_2020_8815195Neuroprotective Effects of the Sonic Hedgehog Signaling Pathway in Ischemic Injury through Promotion of Synaptic and Neuronal Health
Yogarajalakshmi_2020_Aquat.Toxicol_222_105474Toxicological screening of marine red algae Champia parvula (C. Agardh) against the dengue mosquito vector Aedes aegypti (Linn.) and its non-toxicity against three beneficial aquatic predators
Yoneyama_2020_Plant.Direct_4_e00219Hydroxyl carlactone derivatives are predominant strigolactones in Arabidopsis
Yoo_2020_Cell.Chem.Biol_27_143The Antimalarial Natural Product Salinipostin A Identifies Essential alpha/beta Serine Hydrolases Involved in Lipid Metabolism in P. falciparum Parasites
Yoo_2020_Int.J.Biol.Macromol_165_1139Identification, characterization, and immobilization of a novel YbfF esterase from Halomonas elongata
Yoon_2020_Anal.Biochem__113952Optimization and Validation of a Fluorogenic Dipeptidyl Peptidase 4 enzymatic assay in Human Plasma
Yoshimura_2020_Carbohydr.Res_492_108023A new strategy for the chemoenzymatic synthesis of glycopeptides by De-O-acetylation with an esterase and glycosylations with glycosyltransferases
Yost_2020_Int.J.Mol.Sci_21_Abnormal Social Interactions in a Drosophila Mutant of an Autism Candidate Gene: Neuroligin 3
You_2020_Nutrients_12_Mori Cortex Radicis Attenuates High Fat Diet-Induced Cognitive Impairment via an IRS/Akt Signaling Pathway
You_2020_Sci.Rep_10_8400Propoxur resistance associated with insensitivity of acetylcholinesterase (AChE) in the housefly, Musca domestica (Diptera: Muscidae)
Youssef_2020_Toxicol.Appl.Pharmacol__114954Aliskiren and captopril improve cognitive deficits in poorly controlled STZ-induced diabetic rats via amelioration of the hippocampal P-ERK, GSK3beta, P-GSK3beta pathway
Yu_2020_Adv.Exp.Med.Biol_1276_197CGI-58: Versatile Regulator of Intracellular Lipid Droplet Homeostasis
Yu_2020_Bull.Entomol.Res__1Genetic analysis and screening of detoxification-related genes in an amitraz-resistant strain of Panonychus citri
Yu_2020_Ecotoxicol.Environ.Saf_194_110378Complete metabolic study by dibutyl phthalate degrading Pseudomonas sp. DNB-S1
Yu_2020_Enzyme.Microb.Technol_142_109695Rationally design and chemical modification: Getting a new and efficient biocatalyst for Henry reaction
Yu_2020_Food.Funct_11_6643Identification and molecular docking study of fish roe-derived peptides as potent BACE 1, AChE, and BChE inhibitors
Yu_2020_J.Agric.Food.Chem_68_2570Biochemical Characterization and Mutational Analysis of a Lactone Hydrolase from Phialophora americana
Yu_2020_J.Asian.Nat.Prod.Res__1Design and synthesis of 7-diethylaminocoumarin-based 1,3,4-oxadiazole derivatives with anti-acetylcholinesterase activities
Yu_2020_J.Neurol.Neurosurg.Psychiatry_91_1201Evidence-based prevention of Alzheimer's disease: systematic review and meta-analysis of 243 observational prospective studies and 153 randomised controlled trials
Yu_2020_J.Sci.Food.Agric__Identification of ovalbumin-derived peptides as multi-target inhibitors of AChE, BChE and BACE1
Yu_2020_PLoS.One_15_e0238887The DROOPING LEAF (DR) gene encoding GDSL esterase is involved in silica deposition in rice (Oryza sativa L.)
Yu_2020_Toxicol.Appl.Pharmacol__115388Diosgenin alleviates hypercholesterolemia via SRB1/CES-1/CYP7A1/FXR pathway in high-fat diet-fed rats
Yu_2020_World.J.Emerg.Med_11_37Role of penehyclidine in acute organophosphorus pesticide poisoning
Yu_2020_Zhejiang.Da.Xue.Xue.Bao.Yi.Xue.Ban_49_514[Proteolytic cleavage of neuroligins and functions of their cleavage products]
Yu_2020_iScience_23_100866Post-treatment with Posiphen Reduces Endoplasmic Reticulum Stress and Neurodegeneration in Stroke Brain
Yuan_2020_Int.J.Nanomedicine_15_6339Selenium Nanoparticles Pre-Treatment Reverse Behavioral, Oxidative Damage, Neuronal Loss and Neurochemical Alterations in Pentylenetetrazole-Induced Epileptic Seizures in Mice
Yuan_2020_J.Insect.Sci_20_Effect of Tannic Acid on Nutrition and Activities of Detoxification Enzymes and Acetylcholinesterase of the Fall Webworm (Lepidoptera: Arctiidae)
Yuan_2020_J.Virol_94_e01387Molecular Basis of Binding between Middle East Respiratory Syndrome Coronavirus and CD26 from Seven Bat Species
Yuki_2020_Transl.Perioper.Pain.Med_7_185Should we Routinely Reverse Neuromuscular Blockade with Sugammadex in Patients with a History of Heart Transplantation?
Yumoto_2020_Mol.Autism_11_68Autism-associated variants of neuroligin 4X impair synaptogenic activity by various molecular mechanisms
Zacarias-Garcia_2020_Food.Chem__128322Characterization of the Pale Yellow Petal/Xanthophyll Esterase gene family in citrus as candidates for carotenoid esterification in fruits
Zadjelovic_2020_Environ.Microbiol__Beyond oil degradation: Enzymatic potential of Alcanivorax to degrade natural and synthetic polyesters
Zafar_2020_J.Biomol.Struct.Dyn__1Zinc metal carboxylates as Potential anti-Alzheimer's candidate: In-vitro anticholinesterase, antioxidant and molecular docking studies
Zagorska_2020_Molecules_25_Perspectives for New and More Efficient Multifunctional Ligands for Alzheimer's Disease Therapy
Zahoor_2020_J.Basic.Clin.Physiol.Pharmacol__Toxicological, anticholinesterase, antilipidemic, antidiabetic and antioxidant potentials of Grewia optiva Drummond ex Burret extracts
Zaidi_2020_Ann.Pharmacother__1060028020949125Outcomes of Medication Misadventure Among People With Cognitive Impairment or Dementia: A Systematic Review and Meta-analysis
Zaki_2020_Appl.Microbiol.Biotechnol__Microbial acetylcholinesterase inhibitors for Alzheimer's therapy: recent trends on extraction, detection, irradiation-assisted production improvement and nano-structured drug delivery
Zaki_2020_Histochem.Cell.Biol__Nano-curcumin versus curcumin in amelioration of deltamethrin-induced hippocampal damage
Zamanian_2020_Curr.Neuropharmacol__The Protective Roles and Molecular Mechanisms of Troxerutin (vitamin P4) for Treatment of Chronic Diseases: A Mechanistic Review
Zambetti_2020_Blood_135_1772Genetic disruption of N-RasG12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice
Zambrano_2020_Chem.Biol.Interact__109019An in vitro study on the interaction of the anti-Alzheimer drug rivastigmine with human erythrocytes
Zameer_2020_Brain.Res.Bull__Neuroprotective role of alendronate against APP processing and neuroinflammation in mice fed a high fat diet
Zan_2020_Exp.Physiol_105_108Downregulation of microRNA-124 prevents the development of acute liver failure through the upregulation of PIM-3
Zandona_2020_Arch.Toxicol_94_3157Targeting organophosphorus compounds poisoning by novel quinuclidine-3 oximes: development of butyrylcholinesterase-based bioscavengers
Zandona_2020_Int.J.Mol.Sci_21_Vitamin B3-Based Biologically Active Compounds as Inhibitors of Human Cholinesterases
Zanon_2020_J.Biomol.Struct.Dyn__1Design, synthesis, molecular modeling and neuroprotective effects of a new framework of cholinesterase inhibitors for Alzheimer's disease
Zaoui_2020_Chemosphere__129078Effects of ferroelectric oxides of barium strontium titanate (Ba(0.85)Sr(0.15)TiO(3)) nanoparticles on Ruditapes decussatus assessed through chemical, physiological, and biochemical methods
Zdarova_2020_Int.J.Mol.Sci_21_Interaction of Cucurbit[7]uril with Oxime K027, Atropine, and Paraoxon: Risky or Advantageous Delivery System?
Zdarova_2020_Toxicol.Lett_320_64Encapsulation of oxime K027 into cucurbit[7]uril: In vivo evaluation of safety, absorption, brain distribution and reactivation effectiveness
Zeman_2020_Ceska.Slov.Farm_69_24Double-coated pellets with semipermeable ethylcellulose coating for detection of cholinesterase inhibitors
Zeman_2020_J.Pharm.Biomed.Anal_179_113004Unique coated neusilin pellets with a more distinct and fast visual detection of nerve agents and other cholinesterase inhibitors
Zengin_2020_Food.Res.Int_133_109129Chemical characterization, antioxidant, enzyme inhibitory and cytotoxic properties of two geophytes: Crocus pallasii and Cyclamen cilicium
Zengin_2020_Foods_9_705Chemical Characterization and Bioactive Properties of Different Extracts from Fibigia clypeata, an Unexplored Plant Food
Zengin_2020_Foods_9_713Chemical Composition, Antioxidant and Enzyme Inhibitory Properties of Different Extracts Obtained from Spent Coffee Ground and Coffee Silverskin
Zengin_2020_J.Pharm.Biomed.Anal_191_113614Network analysis, chemical characterization, antioxidant and enzyme inhibitory effects of foxglove (Digitalis cariensis Boiss. ex Jaub. & Spach): A novel raw material for pharmaceutical applications
Zeumer_2020_Sci.Total.Environ_723_137974Chronic effects of wastewater-borne silver and titanium dioxide nanoparticles on the rainbow trout (Oncorhynchus mykiss)
Zhai_2020_J.Sci.Food.Agric__Development of a novel nano-based detection card by electrospinning for rapid and sensitive analysis of pesticide residues
Zhan_2020_Bioorg.Chem_102_104136Monoterpene indole alkaloids with acetylcholinesterase inhibitory activity from the leaves of Rauvolfia vomitoria
Zhan_2020_Environ.Res_182_109138New insights into the microbial degradation and catalytic mechanism of synthetic pyrethroids
Zhan_2020_Fitoterapia__104704Peraksine derivatives with potential anti-inflammatory activities from the stems of Rauvolfia vomitoria
Zhan_2020_Phytochemistry_177_112450Monoterpene indole alkaloids with diverse skeletons from the stems of Rauvolfia vomitoria and their acetylcholinesterase inhibitory activities
Zhang_2020_3.Biotech_10_523High-efficiency expression of the thermophilic lipase from Geobacillus thermocatenulatus in Escherichia coli and its application in the enzymatic hydrolysis of rapeseed oil
Zhang_2020_Adv.Sci.(Weinh)_7_1901904Tuning Butyrylcholinesterase Inactivation and Reactivation by Polymer-Based Protein Engineering
Zhang_2020_Arch.Pharm.Res_43_1259Pharmacological effects of harmine and its derivatives: a review
Zhang_2020_BMC.Cardiovasc.Disord_20_295The relationship of lipoprotein-associated phospholipase A2 activity with the seriousness of coronary artery disease
Zhang_2020_Biochem.Biophys.Res.Commun_523_1040Crystal structure and biochemical characterization of Striga hermonthica HYPO-SENSITIVE TO LIGHT 8 (ShHTL8) in strigolactone signaling pathway
Zhang_2020_Biomacromolecules_21_3867Catalytic Detoxification of Organophosphorus Nerve Agents by Butyrylcholinesterase-Polymer-Oxime Bioscavengers
Zhang_2020_Biomed.Pharmacother_126_109907A COX-2/sEH dual inhibitor PTUPB ameliorates cecal ligation and puncture-induced sepsis in mice via anti-inflammation and anti-oxidative stress
Zhang_2020_Biomed.Rep_13_8Total flavonoids of Selaginella pulvinata alleviates cognitive impairment in mice
Zhang_2020_Bioorg.Chem_100_103903Twenty-five limonoids from the Hainan mangrove, Xylocarpus granatum
Zhang_2020_Bioorg.Chem_101_104043N-methoxy-beta-carboline alkaloids with inhibitory activities against Abeta42 aggregation and acetylcholinesterase from the stems of Picrasma quassioides
Zhang_2020_Bioprocess.Biosyst.Eng_43_2131Directed evolution of Aspergillus oryzae lipase for the efficient resolution of (R,S)-ethyl-2-(4-hydroxyphenoxy) propanoate
Zhang_2020_Biotechnol.Prog_36_e2901Optimization of chemoenzymatic Baeyer-Villiger oxidation of cyclohexanone to sigma-caprolactone using response surface methodology
Zhang_2020_Dalton.Trans_49_10261Structures and esterolytic reactivity of novel binuclear copper(ii) complexes with reduced l-serine Schiff bases as mimic carboxylesterases
Zhang_2020_Data.Brief_29_105110Antioxidant property and characterization data of 1-o-galloylglycerol synthesized via enzymatic glycerolysis
Zhang_2020_Ecotoxicology_29_35Esterase-mediated spinosad resistance in house flies Musca domestica (Diptera: Muscidae)
Zhang_2020_Environ.Pollut_263_114471Neurotoxicity of perfluorooctanoic acid and post-exposure recovery due to blueberry anthocyanins in the planarians Dugesia japonica
Zhang_2020_Enzyme.Microb.Technol_132_109408Self-assembly of lipase hybrid nanoflowers with bifunctional Ca(2+) for improved activity and stability
Zhang_2020_Eur.J.Med.Chem_201_112273The structure-based optimization of delta-sultone-fused pyrazoles as selective BuChE inhibitors
Zhang_2020_Evid.Based.Complement.Alternat.Med_2020_5129562Acupotomy Alleviates Energy Crisis at Rat Myofascial Trigger Points
Zhang_2020_Evid.Based.Complement.Alternat.Med_2020_7643528Effect of Massa Medicata Fermentata on the Gut Microbiota of Dyspepsia Mice Based on 16S rRNA Technique
Zhang_2020_Exp.Cell.Res__111856Overexpressed CES2 has prognostic value in CRC and knockdown CES2 reverses L-OHP-resistance in CRC cells by inhibition of the PI3K signaling pathway
Zhang_2020_FEBS.J_287_1666COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence
Zhang_2020_Fish.Physiol.Biochem_46_111Inhibition of intestinal lipases alleviates the adverse effects caused by high-fat diet in Nile tilapia
Zhang_2020_Food.Chem_305_125479Enzymatic synthesis of 1-o-galloylglycerol: Characterization and determination of its antioxidant properties
Zhang_2020_Food.Chem_318_126518Characterization of enzymatically interesterified palm oil-based fats and its potential application as cocoa butter substitute
Zhang_2020_Food.Chem__128604Solvent-free enzymatic synthesis of 1,2-dipalmitoylgalloylglycerol: Characterization and optimization of reaction condition
Zhang_2020_Food.Res.Int_137_109363Ethanol extracts from Cinnamomum camphora seed kernel: Potential bioactivities as affected by alkaline hydrolysis and simulated gastrointestinal digestion
Zhang_2020_Front.Aging.Neurosci_12_132Exploration of the Molecular Mechanism for Lipoprotein Lipase Expression Variations in SH-SY5Y Cells Exposed to Different Doses of Amyloid-Beta Protein
Zhang_2020_Front.Chem_8_730Molecular Dynamics Revealing a Detour-Forward Release Mechanism of Tacrine: Implication for the Specific Binding Characteristics in Butyrylcholinesterase
Zhang_2020_Front.Oncol_10_559568Monoacylglycerol Lipase Knockdown Inhibits Cell Proliferation and Metastasis in Lung Adenocarcinoma
Zhang_2020_Front.Pharmacol_11_760Circumdatin D Exerts Neuroprotective Effects by Attenuating LPS-Induced Pro-Inflammatory Responses and Downregulating Acetylcholinesterase Activity In Vitro and In Vivo
Zhang_2020_Genes.Genomics_42_1227Identifying genes for resistant starch, slowly digestible starch, and rapidly digestible starch in rice using genome-wide association studies
Zhang_2020_Heart.Surg.Forum_23_E579A Soluble Epoxide Hydrolase Inhibitor Upregulated KCNJ12 and KCNIP2 by Downregulating MicroRNA-29 in a Mouse Model of Myocardial Infarction
Zhang_2020_Int.Immunopharmacol_86_106729DL0410 attenuates oxidative stress and neuroinflammation via BDNF/TrkB/ERK/CREB and Nrf2/HO-1 activation
Zhang_2020_Int.J.Biol.Macromol_146_725The degraded polysaccharide from Pyropia haitanensis represses amyloid beta peptide-induced neurotoxicity and memory in vivo
Zhang_2020_Int.J.Biol.Macromol_164_2795Highly regio- and enantio-selective hydrolysis of two racemic epoxides by GmEH3, a novel epoxide hydrolase from Glycine max
Zhang_2020_Int.J.Mol.Sci_21_Genomic Characterization and Expression of Juvenile Hormone Esterase-Like Carboxylesterase Genes in Pacific White Shrimp, Litopenaeus vannamei
Zhang_2020_J.Affect.Disord_270_131Increased expression of soluble epoxide hydrolase in the brain and liver from patients with major psychiatric disorders: A role of brain - liver axis
Zhang_2020_J.Asian.Nat.Prod.Res_22_217Cytotoxic lycodine alkaloids from the aerial parts of Lycopodiastrum casuarinoides
Zhang_2020_J.Biol.Chem_295_16987Mutation of an atypical oxirane oxyanion hole improves regioselectivity of the alpha/beta-fold epoxide hydrolase Alp1U
Zhang_2020_J.Econ.Entomol__Cross-resistance and Fitness Cost Analysis of Resistance to Thiamethoxam in Melon and Cotton Aphid (Hemiptera: Aphididae)
Zhang_2020_J.Integr.Plant.Biol__GDSL esterase/lipases OsGELP34 and OsGELP110/OsGELP115 are essential for rice pollen development
Zhang_2020_J.Mater.Chem.B_8_6459A tunable bifunctional hollow Co(3)O(4)/MO(3) (M = Mo, W) mixed-metal oxide nanozyme for sensing H(2)O(2) and screening acetylcholinesterase activity and its inhibitor
Zhang_2020_J.Microbiol.Biotechnol_30_561Antifungal Effect of Triglycerol Monolaurate Synthesized by Lipozyme 435-Mediated Esterification
Zhang_2020_J.Nanosci.Nanotechnol_20_6168A Comparison of the Resolution of Selective (+/-)-Glycidyl Butyrate by Using Free and Nano-SiO(2) Immobilized Porcine Pancreatic Lipase
Zhang_2020_J.Nat.Prod_83_2940Bioactivity-Guided Discovery of Human Carboxylesterase Inhibitors from the Roots of Paeonia lactiflora
Zhang_2020_J.Pharm.Anal_10_253Rapid bioluminescence assay for monitoring rat CES1 activity and its alteration by traditional Chinese medicines
Zhang_2020_J.Pharm.Sci_109_3300Rapid Polysorbate 80 Degradation by Liver Carboxylesterase in a Monoclonal Antibody Formulated Drug Substance at Early Stage Development
Zhang_2020_J.Phys.Chem.B_124_9812Interaction Mechanism of the Germination Stimulants Karrikins and Their Receptor ShKAI2iB
Zhang_2020_Langmuir__Constructing Cross-linked Nanofibrous Scaffold via Dual-Enzyme-Instructed Hierarchical Assembly
Zhang_2020_Nat.Commun_11_3719Genome assembly of wild tea tree DASZ reveals pedigree and selection history of tea varieties
Zhang_2020_Nat.Prod.Res_34_2802Two new compounds, Talaromycin A and B, isolated from an endophytic fungus, Talaromyces aurantiacus
Zhang_2020_Nat.Prod.Res_34_3531Chemical composition, antioxidant, antibacterial and cholinesterase inhibitory activities of three Juniperus species
Zhang_2020_Neuropeptides__102020Cognitive-enhancing effects of fibrauretine on Abeta1-42-induced Alzheimer's disease by compatibilization with ginsenosides
Zhang_2020_Neurotherapeutics_17_1495Approach to Cognitive Impairment in Parkinson's Disease
Zhang_2020_PLoS.One_15_e0232770Colonization of Beauveria bassiana 08F04 in root-zone soil and its biocontrol of cereal cyst nematode (Heterodera filipjevi)
Zhang_2020_Pestic.Biochem.Physiol_167_104620Molluscicidal activity of fatty acids in the kernel of Chimonanthus praecox cv. Luteus against the golden apple snail Pomacea canaliculata
Zhang_2020_Prostaglandins.Leukot.Essent.Fatty.Acids_162_102180Soluble epoxide hydrolase as a therapeutic target for obesity-induced disorders: roles of gut barrier function involved
Zhang_2020_Protein.Expr.Purif__105721Co-expression of Pseudomonas alcaligenes Lipase and Its Specific Foldase in Pichia pastoris by a Dual Expression Cassette Strategy
Zhang_2020_Sci.Rep_10_1680Significant improvement in catalytic activity and enantioselectivity of a Phaseolus vulgaris epoxide hydrolase, PvEH3, towards ortho-cresyl glycidyl ether based on the semi-rational design
Zhang_2020_Se.Pu_38_1102[Determination of gastrodin activity inhibition on acetylcholinesterase by capillary electrophoresis]
Zhang_2020_Soft.Matter_16_2266Microchamber arrays made of biodegradable polymers for enzymatic release of small hydrophilic cargos
Zhang_2020_Talanta_208_120406Copper(II) complex as a turn on fluorescent sensing platform for acetylcholinesterase activity with high sensitivity
Zhao_2020_Anal.Chim.Acta_1140_228Aptamer-functionalized magnetic nanoparticles conjugated organic framework for immobilization of acetylcholinesterase and its application in inhibitors screening
Zhao_2020_Biomed.Environ.Sci_33_614Coronavirus Disease 2019 versus Influenza A in Children: An Observational Control Study in China
Zhao_2020_Bioorg.Chem_102_104065Inula japonica ameliorated bleomycin-induced pulmonary fibrosis via inhibiting soluble epoxide hydrolase
Zhao_2020_Bioorg.Chem_105_104367Discovery of natural alkaloids as potent and selective inhibitors against human carboxylesterase 2
Zhao_2020_Biosci.Rep__Gene polymorphism associated with Angiotensinogen(M235T), Endothelial lipase (584C/T) and susceptibility to coronary artery disease: A meta-analysis
Zhao_2020_Commun.Biol_3_555Caffeine inhibits Notum activity by binding at the catalytic pocket
Zhao_2020_Comp.Biochem.Physiol.B.Biochem.Mol.Biol__110431Identification and characterization of detoxification genes in two cerambycid beetles, Rhaphuma horsfieldi and Xylotrechus quadripes (Coleoptera: Cerambycidae: Clytini)
Zhao_2020_Environ.Pollut_265_114767Time-dependent stress evidence in dynamic allocation of physiological metabolism of Nilaparvata lugens in response to elevated CO2
Zhao_2020_Food.Chem_327_127061Effect of salt promote the muscle triglyceride hydrolysis during dry-salting by inducing the phosphorylation of adipose tissue triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) and lipid droplets splitting
Zhao_2020_J.Ethnopharmacol__113711Enhanced anti-amnestic effect of donepezil by Ginkgo biloba extract (EGb 761) via further improvement in pro-cholinergic and antioxidative activities
Zhao_2020_J.Pharm.Biomed.Anal_190_113547Screening acetylcholinesterase inhibitors from traditional Chinese medicines by paper-immobilized enzyme combined with capillary electrophoresis analysis
Zhao_2020_Molecules_26_Chemical Composition, Antibacterial, Anti-Inflammatory, and Enzyme Inhibitory Activities of Essential Oil from Rhynchanthus beesianus Rhizome
Zhao_2020_Pestic.Biochem.Physiol_168_104623Susceptibility of fall armyworm, Spodoptera frugiperda (J.E.Smmith), to eight insecticides in China, with special reference to lambda-cyhalothrin
Zhao_2020_Phytochemistry_181_112566Voacafrines A-N, aspidosperma-type monoterpenoid indole alkaloids from Voacanga africana with AChE inhibitory activity
Zhao_2020_Plant.Physiol__RMS2 encoding a GDSL lipase mediates lipid homeostasis in anthers to determine rice male fertility
Zhao_2020_Sci.Total.Environ__143054Environmentally relevant concentration of cypermethrin or/and sulfamethoxazole induce neurotoxicity of grass carp: Involvement of blood-brain barrier, oxidative stress and apoptosis
Zhao_2020_Zhonghua.Wei.Zhong.Bing.Ji.Jiu.Yi.Xue_32_44[Value of serum cholinesterase in the prognosis of septic shock]
Zheleva-Dimitrova_2020_J.Pharm.Biomed.Anal_190_113537Identification of bioactive compounds from Rhaponticoides iconiensis extracts and their bioactivities: An endemic plant to Turkey flora
Zheng_2020_3.Biotech_10_51Immobilization of Lipozyme TL 100L for methyl esterification of soybean oil deodorizer distillate
Zheng_2020_ACS.Appl.Mater.Interfaces_12_35676Electrostatic Effect of Functional Surfaces on the Activity of Adsorbed Enzymes: Simulations and Experiments
Zheng_2020_Food.Funct_11_8472Metabolism and pharmacological activities of the natural health-benefiting compound diosmin
Zheng_2020_J.Biol.Inorg.Chem_25_1009Selenoprotein F knockout leads to glucose and lipid metabolism disorders in mice
Zheng_2020_Org.Biomol.Chem__Catalytic activities of cocaine hydrolases against the most toxic cocaine metabolite norcocaethylene
Zhi_2020_J.Med.Chem__Discovery of Aryl Formyl Piperidine Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase Inhibitors
Zhong_2020_Protein.Expr.Purif_179_105798Characterization of an acidic pectin methylesterase from Paenibacillus xylanexedens and its application in fruit processing
Zhou_2020_Biochem.Biophys.Res.Commun_522_986The Trp183 is essential in lactonohydrolase ZHD detoxifying zearalenone and zearalenols
Zhou_2020_Biochem.Biophys.Res.Commun__Structure of a gut microbial diltiazem-metabolizing enzyme suggests possible substrate binding mode
Zhou_2020_Bioorg.Med.Chem.Lett__127756Novel BuChE-IDO1 inhibitors from sertaconazole: Virtual screening, chemical optimization and molecular modeling studies
Zhou_2020_Cancer.Biother.Radiopharm__Circular RNA cMras Suppresses the Progression of Lung Adenocarcinoma Through ABHD5/ATGL Axis Using NF-B Signaling Pathway
Zhou_2020_Cell.Oncol.(Dordr)_43_461Dp44mT, an iron chelator, suppresses growth and induces apoptosis via RORA-mediated NDRG2-IL6/JAK2/STAT3 signaling in glioma
Zhou_2020_Chem.Res.Toxicol__Donepezil prevents ox-LDL-induced attachment of THP-1 monocytes to human aortic endothelial cells (HAECs)
Zhou_2020_Dose.Response_18_1559325820938526Discovery of a Selective 6-Hydroxy-1, 4-Diazepan-2-one Containing Butyrylcholinesterase Inhibitor by Virtual Screening and MM-GBSA Rescoring
Zhou_2020_Environ.Toxicol.Pharmacol__103499Study on the Regulation of Earthworm Physiological Function under Cadmium Stress Based on a Compound Mathematical Model
Zhou_2020_Eur.J.Med.Chem_200_112415Simple analogues of natural product chelerythrine: Discovery of a novel anticholinesterase 2-phenylisoquinolin-2-ium scaffold with excellent potency against acetylcholinesterase
Zhou_2020_Genome.Biol.Evol__The first draft genome of the plasterer bee Colletes gigas (Hymenoptera: Colletidae: Colletes)
Zhou_2020_J.Integr.Neurosci_19_89Herbal complex 'Buyang Huanwu Tang' improves motor endplate function of denervated-dependent skeletal muscle atrophy in rat
Zhou_2020_J.Neuroimmunol_339_577114Anti-dipeptidyl-peptidase-like protein 6 encephalitis, a rare cause of reversible rapid progressive dementia and insomnia
Zhou_2020_Metab.Brain.Dis__Edaravone at high concentrations attenuates cognitive dysfunctions induced by abdominal surgery under general anesthesia in aged mice
Zhou_2020_Nat.Commun_11_2674The netrin receptor UNC-40/DCC assembles a postsynaptic scaffold and sets the synaptic content of GABAA receptors
Zhou_2020_Neurology_94_e376Apathy rating scores and beta-amyloidopathy in patients with Parkinson disease at risk for cognitive decline
Zhou_2020_Sci.Total.Environ_709_135897Degradation mechanism for Zearalenone ring-cleavage by Zearalenone hydrolase RmZHD: A QM/MM study
Zhou_2020_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_247_119155An OliGreen-responsive fluorescence sensor for sensitive detection of organophosphorus pesticide based on its specific selectivity towards T-Hg(2+)-T DNA structure
Zhou_2020_World.J.Clin.Cases_8_5576No significant association between dipeptidyl peptidase-4 inhibitors and adverse outcomes of COVID-19
Zhu_2020_Biol.Trace.Elem.Res__Liver Function of Male Rats Exposed to Manganese at Different Time Points
Zhu_2020_Bioorg.Med.Chem.Lett_30_127198The discovery of diazetidinyl diamides as potent and reversible inhibitors of monoacylglycerol lipase (MAGL)
Zhu_2020_Bioorg.Med.Chem.Lett_30_127243The discovery of azetidine-piperazine di-amides as potent, selective and reversible monoacylglycerol lipase (MAGL) inhibitors
Zhu_2020_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__108844Effect of age on insecticide susceptibility and enzymatic activities of three detoxification enzymes and one invertase in honey bee workers (Apis mellifera)
Zhu_2020_Genomics_112_379Genome-wide association study of the level of blood components in Pekin ducks
Zhu_2020_J.Microbiol.Biotechnol_30_196Improved Homologous Expression of the Acidic Lipase from Aspergillus niger
Zhu_2020_J.Nat.Prod_83_2831Lycosquarrines A-R, Lycopodium Alkaloids from Phlegmariurus squarrosus
Zhu_2020_Pharmgenomics.Pers.Med_13_405Genetic Testing for BCHE Variants Identifies Patients at Risk of Prolonged Neuromuscular Blockade in Response to Succinylcholine
Zhu_2020_Sci.Total.Environ_715_137037Metagenomic analysis exploring microbial assemblages and functional genes potentially involved in di (2-ethylhexyl) phthalate degradation in soil
Zhu_2020_Zhonghua.Wei.Zhong.Bing.Ji.Jiu.Yi.Xue_32_1491[Effects of Moringa flavone on cognitive function and neuropathological indexes in diabetic encephalopathy rats]
Zhuikov_2020_Polymers.(Basel)_12_Comparative Structure-Property Characterization of Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate)s Films under Hydrolytic and Enzymatic Degradation: Finding a Transition Point in 3-Hydroxyvalerate Content
Zhuo_2020_Sci.Rep_10_17232Active site competition is the mechanism for the inhibition of lipoprotein-associated phospholipase A(2) by detergent micelles or lipoproteins and for the efficacy reduction of darapladib
Zienkiewicz_2020_Front.Plant.Sci_11_579019Degradation of Lipid Droplets in Plants and Algae-Right Time, Many Paths, One Goal
Zondagh_2020_J.Enzyme.Inhib.Med.Chem_35_1596Design, synthesis and biological evaluation of edaravone derivatives bearing the N-benzyl pyridinium moiety as multifunctional anti-Alzheimer's agents
Zorbaz_2020_ACS.Chem.Neurosci__Pharmacokinetic evaluation of brain penetrating morpholine-3-hydroxy-2-pyridine oxime as an antidote for nerve agent poisoning
Zorrilla_2020_J.Agric.Food.Chem_68_9636Synthesis of Active Strigolactone Analogues Based on Eudesmane- and Guaiane-Type Sesquiterpene Lactones
Zou_2020_Appl.Biochem.Biotechnol_191_1294Preparation of DHA-Rich Medium- and Long-Chain Triacylglycerols by Lipase-Catalyzed Acidolysis of Microbial Oil from Schizochytrium sp.with Medium-Chain Fatty Acids
Zou_2020_Appl.Biochem.Biotechnol__Metal-Organic Frameworks Conjugated Lipase with Enhanced Bio-catalytic Activity and Stability
Zou_2020_BMC.Complement.Med.Ther_20_236The botanical origin and antioxidant, anti-BACE1 and antiproliferative properties of bee pollen from different regions of South Korea
Zou_2020_Colloids.Surf.B.Biointerfaces_195_111275Enhancing bio-catalytic activity and stability of lipase nanogel by functional ionic liquids modification
Zou_2020_Drug.Des.Devel.Ther_14_5623Paeoniflorin Alleviates Abnormalities in Rats with Functional Dyspepsia by Stimulating the Release of Acetylcholine
Zou_2020_Int.J.Environ.Health.Res__1The association between polymorphisms in miRNA and the cholinesterase activity of workers in an omethoate-exposed environment
Zribi_2020_Molecules_25_Triazolopyridopyrimidine: A New Scaffold for Dual-Target Small Molecules for Alzheimer's Disease Therapy
Zueva_2020_Biomolecules_10_16081-(3-Tert-Butylphenyl)-2,2,2-Trifluoroethanone as a Potent Transition-State Analogue Slow-Binding Inhibitor of Human Acetylcholinesterase: Kinetic, MD and QM/MM Studies
Zueva_2020_Molecules_25_Steady-State Kinetics of Enzyme-Catalyzed Hydrolysis of Echothiophate, a P-S Bonded Organophosphorus as Monitored by Spectrofluorimetry
Zujalovic_2020_BMC.Anesthesiol_20_287AChE-activity in critically ill patients with suspected septic encephalopathy: a prospective, single-centre study
Zuo_2020_Insect.Sci_27_1224Genetic analysis and molecular detection of resistance to chlorpyrifos mediated by the A216S substitution in acetylcholinesterase-1 in the plant bug Apolygus lucorum
da Silva Correa_2020_Appl.Biochem.Biotechnol_190_574Lipase-Catalyzed Esterification of Geraniol and Citronellol for the Synthesis of Terpenic Esters
da Silva Mesquita_2020_PLoS.One_15_e0239364Alkaloids of Abuta panurensis Eichler: In silico and in vitro study of acetylcholinesterase inhibition, cytotoxic and immunomodulatory activities
da Silva_2020_Biomolecules_10_Reactivation of VX-Inhibited Human Acetylcholinesterase by Deprotonated Pralidoxime. A Complementary Quantum Mechanical Study
da Silva_2020_Nat.Prod.Res__1Chemical constituents and acetylcholinesterase inhibitory activity from the stems of Bauhinia pentandra
da Silva_2020_Neurochem.Res_45_241In Vitro Effects of 2-{4-[Methylthio(methylsulfonyl)]phenyl}-3-substitutedthiazolidin-4-ones on the Acetylcholinesterase Activity in Rat Brain and Lymphocytes: Isoform Selectivity, Kinetic Analysis, and Molecular Docking
da Silva_2020_Neurotox.Res_37_893Synthesis of Quercetin-Metal Complexes, In Vitro and In Silico Anticholinesterase and Antioxidant Evaluation, and In Vivo Toxicological and Anxiolitic Activities
da Silva_2020_Ticks.Tick.Borne.Dis_12_101643In vitro and in silico studies of the larvicidal and anticholinesterase activities of berberine and piperine alkaloids on Rhipicephalus microplus
das Neves_2020_J.Enzyme.Inhib.Med.Chem_35_31Synthesis of thiazolidin-4-ones and thiazinan-4-ones from 1-(2-aminoethyl)pyrrolidine as acetylcholinesterase inhibitors
de Almeida_2020_Nat.Prod.Res__1Isoquinoline alkaloids reduce beta-amyloid peptide toxicity in Caenorhabditis elegans
de Assis_2020_Life.Sci_249_117538In silico, in vitro and in vivo studies indicate resveratrol analogue as a potential alternative for neuroinflammatory disorders
de Bruin-Hoegee_2020_Toxicol.Lett_319_237Contact transfer risk from fentanyl-contaminated RSDL Kit
de Castro_2020_Biomolecules_10_Trends in the Recent Patent Literature on Cholinesterase Reactivators (2016-2019)
de Castro_2020_Int.J.Mol.Sci_21_Understanding the Interaction Modes and Reactivity of Trimedoxime toward MmAChE Inhibited by Nerve Agents: Theoretical and Experimental Aspects
de Freitas Silva_2020_Molecules_25_Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer's Disease
de Gois Morais_2020_J.Comp.Neurol_528_1307Cytoarchitecture and myeloarchitecture of the entorhinal cortex of the common marmoset monkey (Callithrix jacchus)
de Koning_2020_Chem.Biol.Interact__109139Synthesis and in vitro evaluation of novel non-oximes for the reactivation of nerve agent inhibited human acetylcholinesterase
de Lange_2020_PLoS.Negl.Trop.Dis_14_e0008966Taenia larvae possess distinct acetylcholinesterase profiles with implications for host cholinergic signalling
de Lima_2020_Anal.Methods_12_4116Micro- and nano-sized amine-terminated magnetic beads in a ligand fishing assay
de Lima_2020_Carcinogenesis_41_769NDRG1 deficiency is associated with regional metastasis in oral cancer by inducing epithelial-mesenchymal transition
de Matos_2020_J.Med.Chem_63_11663Glucosylpolyphenols as Inhibitors of Abeta-Induced Fyn Kinase Activation and Tau Phosphorylation: Synthesis, Membrane Permeability, and Exploratory Target Assessment within the Scope of Type 2 Diabetes and Alzheimer's Disease
de Menezes_2020_Environ.Sci.Pollut.Res.Int_27_5030Biocontrol potential of methyl chavicol for managing Spodoptera frugiperda (Lepidoptera: Noctuidae), an important corn pest
de O Buanafina_2020_PLoS.One_15_e0240369Probing the role of cell wall feruloylation during maize development by differential expression of an apoplast targeted fungal ferulic acid esterase
de Oliveira_2020_Clin.Neurol.Neurosurg_194_105832Neuropsychiatric feature profiles of patients with Lewy body dementia
de Oliveira_2020_J.Hazard.Mater_404_124152Behavioral and biochemical consequences of Danio rerio larvae exposure to polylactic acid bioplastic
de Oliveira_2020__Appl.Microbiol.Biotechnol_104_8131Harnessing the sponge microbiome for industrial biocatalysts
de Saint Germain_2020_Biorxiv__A Phelipanche ramosa KAI2 Protein Perceives enzymatically Strigolactones and Isothiocyanates
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