Benzylpiperidin-oxoindolin-acetamide-Cpd23
AChE IC50 0.01 microM
General
Type : Derivative of Donepezil,Piperidine,Indole
Chemical_Nomenclature : N-(1-benzylpiperidin-4-yl)-2-(2-oxoindolin-3-yl)acetamide
Canonical SMILES : N1(CCC(CC1)NC(=O)CC2C(NC3=CC=CC=C23)=O)CC4=CC=CC=C4
InChI : InChI=1S\/C22H25N3O2\/c26-21(14-19-18-8-4-5-9-20(18)24-22(19)27)23-17-10-12-25(13-11-17)15-16-6-2-1-3-7-16\/h1-9,17,19H,10-15H2,(H,23,26)(H,24,27)
InChIKey : GODUPZXISYOOQH-UHFFFAOYSA-N
Other name(s) : compound 23
MW : 363.45
Formula : C22H25N3O2
CAS_number :
PubChem :
UniChem : GODUPZXISYOOQH-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families :
Stucture :
Protein :
References (1)
| Title : Investigation, scaffold hopping of novel donepezil-based compounds as anti-Alzhiemer's agents: synthesis, in-silico and pharmacological evaluations - Gupta_2024_Sci.Rep_14_1687 |
| Author(s) : Gupta M , Pant S , Rana P , Kumar A , Prasun C , Nair MS , Paliwal S , Nain S |
| Ref : Sci Rep , 14 :1687 , 2024 |
| Abstract : Gupta_2024_Sci.Rep_14_1687 |
| ESTHER : Gupta_2024_Sci.Rep_14_1687 |
| PubMedSearch : Gupta_2024_Sci.Rep_14_1687 |
| PubMedID: 38242995 |