ESTHER Database

The web site for the the 15th conference on cholinesterases and the 9th on paraoxonases is now open chepon2024 The Organizing Committee is pleased to offer bursaries that will partially cover the registration fee, travel, and accommodation expenses for PhD students or young scientists born in or after 1989. Please submit your application along with your CV to info@chepon2024.com. Deadline: July 31, 2024. Structural insights into rice KAI2 receptor provide functional implications for perception and signal transduction are published by Guercio et al. and sructures of Rice and Arabidopsis thaliana KAI2 receptor will be available soon (8VCZ, 8VD1, 8VD2) Structures of FphE and FphH, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E and H, boronic acid-based compound N34 bound are available (8TFW, 8TAV) and will be published soon by Fellner et al. How does organophosphorus chemical warfare agent exposure affect respiratory physiology in mice? as published by Trancart et al. Design and Synthesis of sEH/HDAC6 Dual-Targeting Inhibitors for the Treatment of Inflammatory Pain are published by Xu et al.. PDB files of sEH28g complex and sEHGL-B437 complex are available from publisher site and will be available soon from RCSB-PDB. Crystal structure of lipase from Pseudomonas aeruginosa reveals an unusual catalytic triad conformation as published by Xu et al. and structure is available (8YZN) Efficient biodegradation of multiple aryloxyphenoxypropionate herbicides by Corynebacterium sp. Z-1 and the proposed degradation mechanism is published by Gao et al. Microplastics biofragmentation and degradation kinetics in the plastivore insect Tenebrio molitor are published by Peng et al.

Molecular insights into the catalytic mechanism of a phthalate ester hydrolase is published by Wang et al. and structures will be soon available (8YQJ, 8YQP)

An important review on macromolecular interactions of lipoprotein lipase (LPL) is published by Anna Wheless et al. Lowering pH optimum of activity of SshEstI, a slightly alkaliphilic archaeal esterase of the hormone-sensitive lipase family is published by Ohara et al. and structures are available (8YFY, 8YFZ) The potential protective role of hCES1 against Homocysteine thiolactone (HTL)-associated toxicity is published by Hou et al.

The global distribution of the macrolide esterase EstX from the alpha/beta hydrolase superfamily is published by Lin et al. (ecoli-estX, Aclacinomycin-methylesterase_RdmC)

Lowering pH optimum of activity of SshEstI, a slightly alkaliphilic archaeal esterase of the hormone-sensitive lipase family is published by Wang et al. and structures will be available soon (8YFY, 8YFZ) Late stage melanoma is hallmarked by low NLGN4X expression leading to HIF1A accumulation as published by Schorghofer et al. MDGAs (partner of neuroligins) perform activity-dependent synapse type-specific suppression via distinct extracellular mechanisms as published by Kim et al.