| Title : The alpha\/beta hydrolase fold family of proteins database and the cholinesterase gene server ESTHER - Cousin_1997_Nucleic.Acids.Res_25_143 |
| Author(s) : Cousin X , Hotelier T , Giles K , Lievin P , Toutant JP , Chatonnet A |
| Ref : Nucleic Acids Research , 25 :143 , 1997 |
| Abstract : ESTHER (for esterases, alpha/betahydrolase enzyme and relatives) is a database of sequences phylogenetically related to cholinesterases. These sequences define a homogeneous group of enzymes (carboxylesterases, lipases and hormone-sensitive lipases) sharing a similar structure of a central beta-sheet surrounded by alpha-helices. Among these proteins a wide range of functions can be found (hydrolases, adhesion molecules, hormone precursors). The purpose of ESTHER is to help comparison of structures and functions of members of the family. Since the last release, new features have been added to the server. A BLAST comparison tool allows sequence homology searches within the database sequences. New sections are available: kinetics and inhibitors of cholinesterases, fasciculin-acetylcholinesterase interaction and a gene structure review. The mutation analysis compilation has been improved with three-dimensional images. A mailing list has been created. |
| ESTHER : Cousin_1997_Nucleic.Acids.Res_25_143 |
| PubMedSearch : Cousin_1997_Nucleic.Acids.Res_25_143 |
| PubMedID: 9016525 |
Cousin X, Hotelier T, Giles K, Lievin P, Toutant JP, Chatonnet A (1997)
The alpha\/beta hydrolase fold family of proteins database and the cholinesterase gene server ESTHER
Nucleic Acids Research
25 :143
Cousin X, Hotelier T, Giles K, Lievin P, Toutant JP, Chatonnet A (1997)
Nucleic Acids Research
25 :143