Family_XVII

ESTHER family : Fungal-Bact_LIP

Comment :
Secretory lipases. Fungal-Bact_LIP is a new family as described by Neugnot et al. and Hube et al. These lipases are expressed and secreted during the infection cycle of these pathogens. In particular, C. albicans has a large number of different lipases, possibly reflecting broad lipolytic activity, which may contribute to the persistence and virulence of C. albicans in human tissue. Bassegoda et al. defined the bacterial members of this family as Family X.2 of of updated Bacterial lipases classification (Family 10.2). Castilla et al. Defined a new lipase family (Family XVII) (Family 17) with a novel thermophilic and halophilic esterase from Janibacter sp. R02 as the first member of this subfamily