D64EfsX56_human-cb069

General

Gene Locus : human-cb069, human-cb069, human-cb069

Mode of mutation : Natural mutant

Disease : Combined oxidative phosphorylation deficiency-53 (COXPD53)

Summary :

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification :

Torpedo_number : No torpedo number

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
Werren et al. (2023) identified a frameshift variant c.187_191dupGCCGA, p.D64Efs*56 in an individual with clinical presentation of COXPD53 with developmental regression and autistic features

References (3)

Title : A novel biallelic frameshift variant in C2orf69 causing developmental regression, seizures, microcephaly, autistic features, and hypertonia - Werren_2023_Am.J.Med.Genet.A_191_2446
Author(s) : Werren EA , Srinivasan VM , Gowda VK , Pandey A , Vaish S , Kabbur AR , Nandeesh BN , Srivastava A
Ref : American Journal of Medicine Genet A , 191 :2446 , 2023
Abstract :
PubMedSearch : Werren_2023_Am.J.Med.Genet.A_191_2446
PubMedID: 37337918
Gene_locus related to this paper: human-cb069

Title : A novel biallelic frameshift variant in C2orf69 causing developmental regression, seizures, microcephaly, autistic features, and hypertonia - Werren_2023_Am.J.Med.Genet.A_191_2446
Author(s) : Werren EA , Srinivasan VM , Gowda VK , Pandey A , Vaish S , Kabbur AR , Nandeesh BN , Srivastava A
Ref : American Journal of Medicine Genet A , 191 :2446 , 2023
Abstract :
PubMedSearch : Werren_2023_Am.J.Med.Genet.A_191_2446
PubMedID: 37337918
Gene_locus related to this paper: human-cb069

Title : A novel biallelic frameshift variant in C2orf69 causing developmental regression, seizures, microcephaly, autistic features, and hypertonia - Werren_2023_Am.J.Med.Genet.A_191_2446
Author(s) : Werren EA , Srinivasan VM , Gowda VK , Pandey A , Vaish S , Kabbur AR , Nandeesh BN , Srivastava A
Ref : American Journal of Medicine Genet A , 191 :2446 , 2023
Abstract :
PubMedSearch : Werren_2023_Am.J.Med.Genet.A_191_2446
PubMedID: 37337918
Gene_locus related to this paper: human-cb069