D72G_torca-ACHE

General

Gene Locus : torca-ACHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Substrate inhibition steric blockade Mallender_2000_Biochemistry_39_7753

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Substrate inhibition

Torpedo_number : 72

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
p.D72G Asp72Gly

References (1)

Title : Acetylthiocholine binds to asp74 at the peripheral site of human acetylcholinesterase as the first step in the catalytic pathway - Mallender_2000_Biochemistry_39_7753
Author(s) : Mallender WD , Szegletes T , Rosenberry TL
Ref : Biochemistry , 39 :7753 , 2000
Abstract :
PubMedSearch : Mallender_2000_Biochemistry_39_7753
PubMedID: 10869180