I214V_bacdo-ACHE

General

Gene Locus : bacdo-ACHE

Mode of mutation : Natural mutant

Disease :

Summary : OP-resistance OP-resistance (Fenitrothion) Hsu_2006_Insect.Biochem.Mol.Biol_36_396

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : OP-resistance

Torpedo_number : 129

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
In the resistant strain analysed I214V G488S Q643R are associated and homozygous. The position 643 in B. dorsalis is not homologous to Torpedo AChE || p.Ile124Val

References (1)

Title : Mutations in the acetylcholinesterase gene of Bactrocera dorsalis associated with resistance to organophosphorus insecticides - Hsu_2006_Insect.Biochem.Mol.Biol_36_396
Author(s) : Hsu JC , Haymer DS , Wu WJ , Feng HT
Ref : Insect Biochemistry & Molecular Biology , 36 :396 , 2006
Abstract :
PubMedSearch : Hsu_2006_Insect.Biochem.Mol.Biol_36_396
PubMedID: 16651186
Gene_locus related to this paper: bacdo-ACHE