Gene Locus : bemta-ACHE1
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Insecticide sensitivity Insecticide sensitivity Kim_2022_Pestic.Biochem.Physiol_182_105039
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Insecticide sensitivity
Torpedo_number : 329
Kinetic Parameter : No kinetic parameter
News : No news
Comment :
p.Asn390Tyr N329Y with Torpedo numbering. The artificial substitution of N390 (wild form) to Y (putative ancient form) led to reduced catalytic efficiency and increased inhibition by glycoalkaloids, suggesting that the Y390N substitution in BtAChE1 may have been required for Solanaceae host adaptation
| Title : Molecular and kinetic characterization of two acetylcholinesterases with particular focus on the roles of two amino acid substitutions (Y390N and F392W) in Bemisia tabaci - Kim_2022_Pestic.Biochem.Physiol_182_105039 |
| Author(s) : Kim S , Yoon KA , Cho S , Lee SH |
| Ref : Pestic Biochem Physiol , 182 :105039 , 2022 |
| Abstract : |
| PubMedSearch : Kim_2022_Pestic.Biochem.Physiol_182_105039 |
| PubMedID: 35249657 |
| Gene_locus related to this paper: bemta-ACHE1 , bemta-ACHE2 |