Gene Locus : lepde-ACHE
Mode of mutation : Natural mutant
Disease :
Summary : OP-resistance Natural mutation Resistance to azinphosmethyl Zhu_1996_Pestic.Biochem.Physiol_55_100
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : OP-resistance
Torpedo_number : 238
Kinetic Parameter : No kinetic parameter
News : JULY-05-2006
Comment :
The genbank entry correspond to the mutated enzyme (S291G) the azinphosmethyl resistant strain AZ-R. The BERTS strain of colorado potato beetle is highly resistant to N-methyl carbofuran but relatively susceptible to azinphosmethyl || p.Ser291Gly
| Title : Sequence variation and regulatory variation in acetylcholinesterase genes contribute to insecticide resistance in different populations of Leptinotarsa decemlineata - Margus_2021_Ecol.Evol_11_15995 |
| Author(s) : Margus A , Piiroinen S , Lehmann P , Grapputo A , Gilbert L , Chen YH , Lindstrom L |
| Ref : Ecol Evol , 11 :15995 , 2021 |
| Abstract : |
| PubMedSearch : Margus_2021_Ecol.Evol_11_15995 |
| PubMedID: 34824806 |
| Gene_locus related to this paper: lepde-ACHE |
| Title : Pre-invasion history and demography shape the genetic variation in the insecticide resistance-related acetylcholinesterase 2 gene in the invasive Colorado potato beetle - Piiroinen_2013_BMC.Evol.Biol_13_13 |
| Author(s) : Piiroinen S , Lindstrom L , Lyytinen A , Mappes J , Chen YH , Izzo V , Grapputo A |
| Ref : BMC Evol Biol , 13 :13 , 2013 |
| Abstract : |
| PubMedSearch : Piiroinen_2013_BMC.Evol.Biol_13_13 |
| PubMedID: 23331855 |
| Gene_locus related to this paper: lepde-ACHE |
| Title : Molecular diagnostic for detecting the acetylcholinesterase mutations in insecticide-resistant populations of Colorado potato beetle, Leptinotarsa decemlineata (Say) - Malek mohammadi_2012_Pestic.Biochem.Physiol_104_150 |
| Author(s) : Malek mohammadi M , Hejazi MJ , Mossadegh MS , Galehdari H , Khanjani M , Goodarzi MT |
| Ref : , 104 :150 , 2012 |
| Abstract : |
| PubMedSearch : Malek mohammadi_2012_Pestic.Biochem.Physiol_104_150 |
| PubMedID: |
| Gene_locus related to this paper: lepde-ACHE |
| Title : Target site insensitivity mutations in the AChE and LdVssc1 confer resistance to pyrethroids and carbamates in Leptinotarsa decemlineata in northern Xinjiang Uygur autonomous region - Jiang_2011_Pestic.Biochem.Physiol_100_74 |
| Author(s) : Jiang W-H , Guo W-C , Lu W-P , Shi X-Q , Xiong M-H , Wang Z-T , Li G-Q |
| Ref : Pesticide Biochemistry and Physiology , 100 :74 , 2011 |
| Abstract : |
| PubMedSearch : Jiang_2011_Pestic.Biochem.Physiol_100_74 |
| PubMedID: |
| Gene_locus related to this paper: lepde-ACHE |
| Title : Detection of organophosphate and pyrethroid resistance alleles in Czech Leptinotarsa decemlineata (Coleoptera: Chrysomelidae) populations by molecular methods - Zichova_2010_Pest.Manag.Sci_66_853 |
| Author(s) : Zichova T , Kocourek F , Salava J , Nad'ova K , Stara J |
| Ref : Pest Manag Sci , 66 :853 , 2010 |
| Abstract : |
| PubMedSearch : Zichova_2010_Pest.Manag.Sci_66_853 |
| PubMedID: 20603875 |
| Gene_locus related to this paper: lepde-ACHE |
| Title : Functional analysis of mutations in expressed acetylcholinesterasenext term that result in azinphosmethyl and carbofuran resistance in Colorado potato beetle - Kim_2007_Pestic.Biochem.Physiol_88_181 |
| Author(s) : Kim HJ , Yoon KS , Clark JM |
| Ref : Pesticide Biochemistry and Physiology , 88 :181 , 2007 |
| Abstract : |
| PubMedSearch : Kim_2007_Pestic.Biochem.Physiol_88_181 |
| PubMedID: |
| Gene_locus related to this paper: lepde-ACHE |
| Title : Target site insensitivity and mutational analysis of acetylcholinesterase from a carbofuran-resistant population of Colorado potato beetle, Leptinotarsa decemlineata (Say) - Kim_2006_Pestic.Biochem.Physiol_84_165 |
| Author(s) : Kim HJ , Dunnb JB , Yoon KS , Clark JM |
| Ref : Pesticide Biochemistry and Physiology , 84 :165 , 2006 |
| Abstract : |
| PubMedSearch : Kim_2006_Pestic.Biochem.Physiol_84_165 |
| PubMedID: |
| Gene_locus related to this paper: lepde-ACHE |
| Title : DNA-based genotyping techniques for the detection of point mutations associated with insecticide resistance in Colorado potato beetle Leptinotarsa decemlineata - Clark_2001_Pest.Manag.Sci_57_968 |
| Author(s) : Clark JM , Lee SH , Kim HJ , Yoon KS , Zhang A |
| Ref : Pest Manag Sci , 57 :968 , 2001 |
| Abstract : |
| PubMedSearch : Clark_2001_Pest.Manag.Sci_57_968 |
| PubMedID: 11695191 |
| Gene_locus related to this paper: lepde-ACHE |
| Title : An Efficient Strategy for Validation of a Point Mutation Associated with Acetylcholinesterase Sensitivity to Azinphosmethyl in Colorado Potato Beetle - Zhang_1999_Pestic.Biochem.Physiol_65_25 |
| Author(s) : Zhang A , Dunn JB , Clark JM |
| Ref : Pesticide Biochemistry and Physiology , 65 :25 , 1999 |
| Abstract : |
| PubMedSearch : Zhang_1999_Pestic.Biochem.Physiol_65_25 |
| PubMedID: |
| Gene_locus related to this paper: lepde-ACHE |
| Title : Validation of a Point Mutation of Acetylcholinesterase in Colorado Potato Beetle by Polymerase Chain Reaction Coupled to Enzyme Inhibition Assay - Zhu_1997_Pestic.Biochem.Physiol_57_28 |
| Author(s) : Zhu KY , Clark JM |
| Ref : Pesticide Biochemistry and Physiology , 57 :28 , 1997 |
| Abstract : |
| PubMedSearch : Zhu_1997_Pestic.Biochem.Physiol_57_28 |
| PubMedID: |
| Gene_locus related to this paper: lepde-ACHE |
| Title : A Point Mutation of Acetylcholinesterase Associated with Azinphosmethyl Resistance and Reduced Fitness in Colorado Potato Beetle - Zhu_1996_Pestic.Biochem.Physiol_55_100 |
| Author(s) : Zhu KY , Lee SH , Clark JM |
| Ref : Pestic Biochem Physiol , 55 :100 , 1996 |
| Abstract : |
| PubMedSearch : Zhu_1996_Pestic.Biochem.Physiol_55_100 |
| PubMedID: 8980034 |
| Gene_locus related to this paper: lepde-ACHE |