W417C_human-LPL

General

Gene Locus : human-LPL

Mode of mutation : Natural mutant

Disease : Hyperlipoproteinemia TypeI

Summary :

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification :

Torpedo_number : No torpedo number

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
p.W417C Trp417Cys c.1251G>C in patients with severe hypertriglyceridemia (HTG)

References (1)

Title : Reduced activity of two LPL C-terminal variants, p.Glu396Val and novel p.Trp417Cys: a clinical, biochemical and structural study - Tang_2026_Front.Physiol_17_1820368
Author(s) : Tang J , Huang Q , Xie Y , Qiu X , Wang H , Xue M , Dai Z
Ref : Front Physiol , 17 :1820368 , 2026
Abstract :
PubMedSearch : Tang_2026_Front.Physiol_17_1820368
PubMedID: 42359252
Gene_locus related to this paper: human-LPL