Cl-HIN

General

Type : Oxime

Chemical_Nomenclature : 5-chloro-3-nitroso-1H-indol-2-ol

Canonical SMILES : C1=CC2=C(C=C1Cl)C(=C(N2)O)N=O

InChI : InChI=1S\/C8H5ClN2O2\/c9-4-1-2-6-5(3-4)7(11-13)8(12)10-6\/h1-3,10,12H

InChIKey : YEMCVLHZEIKIKZ-UHFFFAOYSA-N

Other name(s) : 5-Chloro-1H-indole-2,3-dione 3-oxime  ||  (3Z)-5-chloro-1H-indole-2,3-dione 3-oxime  ||  1H-Indole-2,3-dione, 5-chloro-, 3-oxime  ||  5-Chlorisatin-3-oxim  ||  CHEMBL1380627


MW : 196.59

Formula : C8H5ClN2O2

CAS_number : 85124-16-9

PubChem : 198612

UniChem : YEMCVLHZEIKIKZ-UHFFFAOYSA-N

Target

Structure : No structure

Families : No family

References (4)

Title : Potential role of a newly AChE reactivator in the depressive-like behavior induced by malathion - Savall_2021_Neurosci.Lett__135697
Author(s) : Savall ASP , Fidelis EM , Quines CB , Bresolin L , Gervini V , Pinton S
Ref : Neuroscience Letters , :135697 , 2021
Abstract :
PubMedSearch : Savall_2021_Neurosci.Lett__135697
PubMedID: 33540058

Title : Pre-clinical evidence of safety and protective effect of isatin and oxime derivatives against malathion-induced toxicity - Savall_2020_Basic.Clin.Pharmacol.Toxicol_126_399
Author(s) : Savall ASP , Fidelis EM , Gutierrez MEZ , Martins BB , Gervini VC , Puntel RL , Roos DH , Avila DS , Pinton S
Ref : Basic Clin Pharmacol Toxicol , 126 :399 , 2020
Abstract :
PubMedSearch : Savall_2020_Basic.Clin.Pharmacol.Toxicol_126_399
PubMedID: 31694074

Title : Antidepressant-like effect of (3Z)-5-Chloro-3-(hydroxyimino)indolin-2-one in rats exposed to malathion: Involvement of BDNF-Trkbeta pathway and AChE - Savall_2020_Life.Sci__117892
Author(s) : Savall ASP , Fidelis EM , Angonesi V , Bresolin L , Gervini VC , Quines C , Puntel RL , Roos DH , de Avila DS , Pinton S
Ref : Life Sciences , :117892 , 2020
Abstract :
PubMedSearch : Savall_2020_Life.Sci__117892
PubMedID: 32502538

Title : (3Z)-5-Chloro-3-(Hydroxyimino)indolin-2-one attenuates hyperglycemia, increased hepatic glycogen content and hepatic damage induced by malathion acute exposure in rats - da Luz Abreu_2019_Nutr.Metab.(Lond)_16_61
Author(s) : da Luz Abreu E , Savall ASP , Boneberg AA , Martins BB , Gervini VC , Sampaio TB , Fajardo AR , Paroul N , Roos DH , Pinton S
Ref : Nutr Metab (Lond) , 16 :61 , 2019
Abstract :
PubMedSearch : da Luz Abreu_2019_Nutr.Metab.(Lond)_16_61
PubMedID: 31516541