Alanylphosphatidylglycerol
Specific aminoacylation of the phospholipid phosphatidylglycerol (PG) with alanine (or with lysine) was shown to render various bacteria less susceptible to antimicrobial agents and environmental stresses
General
Type : Phosphatidylglycerol, Laurate, Dodecanoate
Chemical_Nomenclature : [(2R)-3-[[(2R)-3-[(2S)-2-aminopropanoyl]oxy-2-hydroxypropoxy]-hydroxyphosphoryl]oxy-2-dodecanoyloxypropyl] dodecanoate
Canonical SMILES : CCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCC(COC(=O)C(C)N)O)OC(=O)CCCCCCCCCCC
InChI : InChI=1S\/C33H64NO11P\/c1-4-6-8-10-12-14-16-18-20-22-31(36)41-26-30(45-32(37)23-21-19-17-15-13-11-9-7-5-2)27-44-46(39,40)43-25-29(35)24-42-33(38)28(3)34\/h28-30,35H,4-27,34H2,1-3H3,(H,39,40)\/t28-,29+,30+\/m0\/s1
InChIKey : ZXAVHCQVHRXXOF-FRXPANAUSA-N
Other name(s) : A-PG || (R)-3-(((S)-((R)-3-((L-alanyl)oxy)-2-hydroxypropoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl didodecanoate || Ala-phosphatidylglycerol || DTXSID80984334
MW : 681.8
Formula : C33H64NO11P
CAS_number : 65848-04-6
PubChem : 191782
UniChem : ZXAVHCQVHRXXOF-FRXPANAUSA-N
Target
Structures : No structure
Families : VirJ
References (1)
| Title : Identification and characterization of a periplasmic aminoacyl-phosphatidylglycerol hydrolase responsible for Pseudomonas aeruginosa lipid homeostasis - Arendt_2013_J.Biol.Chem_288_24717 |
| Author(s) : Arendt W , Groenewold MK , Hebecker S , Dickschat JS , Moser J |
| Ref : Journal of Biological Chemistry , 288 :24717 , 2013 |
| Abstract : |
| PubMedSearch : Arendt_2013_J.Biol.Chem_288_24717 |
| PubMedID: 23792962 |
| Gene_locus related to this paper: pseae-q9i538 |