DTNB

General

Type : Chemiluminescent Probe

Chemical_Nomenclature : 5-[(3-carboxy-4-nitrophenyl)disulfanyl]-2-nitrobenzoic acid

Canonical SMILES : C1=CC(=C(C=C1SSC2=CC(=C(C=C2)[N+](=O)[O-])C(=O)O)C(=O)O)[N+](=O)[O-]

InChI : InChI=1S\/C14H8N2O8S2\/c17-13(18)9-5-7(1-3-11(9)15(21)22)25-26-8-2-4-12(16(23)24)10(6-8)14(19)20\/h1-6H,(H,17,18)(H,19,20)

InChIKey : KIUMMUBSPKGMOY-UHFFFAOYSA-N

Other name(s) : 5,5'-Dithiobis(2-nitrobenzoic acid)  ||  Ellman's Reagent  ||  3-Carboxy-4-nitrophenyl disulfide  ||  CHEMBL395814  ||  CHEBI:86228  ||  SCHEMBL26775  ||  ZINC2041301


MW : 396.4

Formula : C14H8N2O8S2

CAS_number : 69-78-3

PubChem : 6254

UniChem : KIUMMUBSPKGMOY-UHFFFAOYSA-N

Target

Families : No family

References (5)

Title : Does chlorpromazine interfere with the Porter-Silber reaction? -
Author(s) : Ellman GL
Ref : Clinica Chimica Acta , 35 :79 , 1971
PubMedID: 5127009

Title : Sulfhydryl groups in Nissl bodies -
Author(s) : Ellman GL , Gan GL
Ref : Experimental Brain Research , 9 :261 , 1969
PubMedID: 5371953

Title : Disulfide and sulfhydryl compounds in TCA extracts of human blood and plasma -
Author(s) : Ellman GL , Lysko H
Ref : Journal of Laboratory & Clinical Medicine , 70 :518 , 1967
PubMedID: 6038554

Title : Sulfhydryl reactivity in the central nervous system: effects of electro-shock -
Author(s) : Ellman GL , Sullivan CV
Ref : Experimental Neurology , 13 :191 , 1965
PubMedID: 5838162

Title : A new and rapid colorimetric determination of acetylcholinesterase activity -
Author(s) : Ellman GL , Courtney KD , Andres V , Featherstone RM , Andres V, Jr.
Ref : Biochemical Pharmacology , 7 :88 , 1961
PubMedID: 13726518