Lyso-ornithine-lipid

OlsI, a member of the alpha/beta fold hydrolase family, is an O-acyltransferase that completes the OlsHI pathway, a third pathway for ornithine lipid biosynthesis, found in planctomycetes

General

Type : Alkyl ester

Chemical_Nomenclature : (2S)-5-amino-2-(3-hydroxyhexadecanoylamino)pentanoic acid

Canonical SMILES : CCCCCCCCCCCCCC(CC(=O)N[C@@H](CCCN)C(=O)O)O

InChI : InChI=1S\/C21H42N2O4\/c1-2-3-4-5-6-7-8-9-10-11-12-14-18(24)17-20(25)23-19(21(26)27)15-13-16-22\/h18-19,24H,2-17,22H2,1H3,(H,23,25)(H,26,27)\/t18?,19-\/m0\/s1

InChIKey : UUMBWNXCQGDFKZ-GGYWPGCISA-N

Other name(s) : lyso-ornithine lipid  ||  LOL  ||  NAOrn 16:0\;O  ||  SCHEMBL3211955  ||  LMFA08020242  ||  alpha-N-(3-hydroxyhexadecanoyl) L-ornithine


MW : 386.6

Formula : C21H42N2O4

CAS_number :

PubChem : 54372927

UniChem : UUMBWNXCQGDFKZ-GGYWPGCISA-N

Target

Structures : No structure

Families : OlsI-acyltransferase

References (1)

Title : A biosynthetic pathway for ornithine lipid formation dependent on a GH3 (Gretchen Hagen 3)-like enzyme in planctomycetes - Rivera-Najera_2025_J.Biol.Chem_301_110634
Author(s) : Rivera-Najera LY , Cruz-Aguilar EM , Vences-Guzman M , Rivas-Marin E , Valdez IRV , Escobedo-Hinojosa W , Guan Z , Farias-Rico JA , Devos DP , Sohlenkamp C
Ref : Journal of Biological Chemistry , 301 :110634 , 2025
Abstract :
PubMedSearch : Rivera-Najera_2025_J.Biol.Chem_301_110634
PubMedID: 40882916
Gene_locus related to this paper: sinad-l0dav0