Tempo-2-C12
Amphiphilic, nitroxide stable containing ester, combined with T80 (Tween 80) forms radical containing micellar probe hydrolysed by esterases, thus yielding narrow electron paramagnetic resonance (EPR) signals whose intensities correlate directly with specific enzymatic activity
General
Chemical_Nomenclature : (2,2,6,6-tetramethyl-4-piperidyl-1-oxyl)decanoate
Canonical SMILES : C(CCCCCCCCCCC)(=O)OC1CC(N(C(C1)(C)C)[O-])(C)C
InChI : InChI=1S\/C21H40NO3\/c1-6-7-8-9-10-11-12-13-14-15-19(23)25-18-16-20(2,3)22(24)21(4,5)17-18\/h18H,6-17H2,1-5H3\/q-1
InChIKey : KQMQYEWHPYTIOR-UHFFFAOYSA-N
Other name(s) : 4-decanoyloxy-2,2,6,6-tetramethylpiperadinyl-1-oxy || T2C12 || (2,2,6,6-tetramethyl-4-piperidyl-1-oxyl)caproate
Target
Structures : No structure
Families : No family
References (2)
| Title : A radical containing micellar probe for assessing esterase enzymatic activity with ultra-low field Overhauser-enhanced magnetic resonance imaging - Elkhanoufi_2024_J.Mater.Chem.B__ |
| Author(s) : Elkhanoufi S , Rakhshan S , Nespeca MJ , Alberti D , Boudries D , Pokong-Touyam J , Stefania R , Parzy E , Massot P , Mellet P , Franconi JM , Thiaudiere E , Geninatti Crich S |
| Ref : J Mater Chem B , : , 2024 |
| Abstract : |
| PubMedSearch : Elkhanoufi_2024_J.Mater.Chem.B__ |
| PubMedID: 39331028 |
| Title : Highly sensitive off\/on EPR probes to monitor enzymatic activity - Elkhanoufi_2022_Chemistry__ |
| Author(s) : Elkhanoufi S , Stefania R , Alberti D , Baroni S , Aime S , Geninatti Crich S |
| Ref : Chemistry , : , 2022 |
| Abstract : |
| PubMedSearch : Elkhanoufi_2022_Chemistry__ |
| PubMedID: 35175676 |