amyme-RIFR

Amycolatopsis mediterranei (Nocardia mediterranei) rifr Thioesterase domain

Comment

Relationship

Family : Thioesterase

Block : X

Position in NCBI Life Tree : Amycolatopsis mediterranei

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Actinobacteria [phylum] N E > Actinobacteria [class] N E > Pseudonocardiales N E > Pseudonocardiaceae N E > Amycolatopsis N E > Amycolatopsis mediterranei N E

Molecular evidence

Database

Sequence

Peptide

MHRPEAEKWL RRFERAPDAR ARLVCLPHAG GSASFFFPLA KALAPAVEVL AVQYPGRQDR RHEPPVDSIG GLTNRLLEVL RPFGDRPLAL FGHSMGAIIG YELALRMPEA GLPAPVHLFA SGRRAPSRYR DDDVRGASDE RLVAELRKLG GSDAAMLADP ELLAMVLPAI RSDYRAVETY RHEPGRRVDC PVTVFTGDHD PRVSVGEARA WEEHTTGPAD LRVLPGGHFF LVDQAAPMIA TMTEKLAGPA LTGSTGGNS

References (4)

Title : Structure and functional analysis of RifR, the type II thioesterase from the rifamycin biosynthetic pathway - Claxton_2009_J.Biol.Chem_284_5021
Author(s) : Claxton HB , Akey DL , Silver MK , Admiraal SJ , Smith JL
Ref : Journal of Biological Chemistry , 284 :5021 , 2009
PubMedID: 19103602
Gene_locus related to this paper: amyme-RIFR

Title : Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699 - Yu_2001_J.Biol.Chem_276_12546
Author(s) : Yu T-W , Mueller R , Mueller M , Zhang X , Draeger G , Kim C-G , Leistner E , Floss HG , Yu TW , Muller R , Muller M , Kim CG
Ref : Journal of Biological Chemistry , 276 :12546 , 2001
PubMedID: 11278540
Gene_locus related to this paper: amyme-ester , amyme-RIFR

Title : Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699 - August_1998_Chem.Biol_5_69
Author(s) : August PR , Tang L , Yoon YJ , Ning S , Muller R , Yu TW , Taylor M , Hoffmann D , Kim CG , Zhang X , Hutchinson CR , Floss HG
Ref : Chemical Biology , 5 :69 , 1998
PubMedID: 9512878
Gene_locus related to this paper: amyme-ester , amyme-RIFR

Title : 3-Amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics - Kim_1998_J.Biol.Chem_273_6030
Author(s) : Kim CG , Yu TW , Fryhle CB , Handa S , Floss HG
Ref : Journal of Biological Chemistry , 273 :6030 , 1998
PubMedID: 9497318
Gene_locus related to this paper: amyme-ester , amyme-RIFR