Benzofuran-carbonyl-benzyloxy-piperidine-Cpd8
Compound 8 Highly selective for T.urticae AChE IC50 1.508 mM over human AChE
General
Type : Benzofuran,Piperidine,Acaricide
Chemical_Nomenclature : 1-benzofuran-5-yl-(4-phenylmethoxypiperidin-1-yl)methanone
Canonical SMILES : C1CN(CCC1OCC2=CC=CC=C2)C(=O)C3=CC4=C(C=C3)OC=C4
InChI : InChI=1S\/C21H21NO3\/c23-21(18-6-7-20-17(14-18)10-13-24-20)22-11-8-19(9-12-22)25-15-16-4-2-1-3-5-16\/h1-7,10,13-14,19H,8-9,11-12,15H2
InChIKey : PHKLTQWFSRBAPO-UHFFFAOYSA-N
Other name(s) : 1-(1-benzofuran-5-ylcarbonyl)-4-(benzyloxy) piperidine
MW : 335.4
Formula : C21H21NO3
CAS_number :
PubChem : 70776292
UniChem : PHKLTQWFSRBAPO-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : Benzofuran-carbonyl-benzyloxy-piperidine-Cpd8 ligand of proteins in family: ACHE
Stucture :
Protein : 9acar-m9t420
References (1)
| Title : Discovery selective acetylcholinesterase inhibitors to control Tetranychus urticae (Acari: Tetranychidae) - Wang_2023_J.Insect.Sci_23_19 |
| Author(s) : Wang J , Cao Y , Lai B , Liu Y , Li C , Bu C |
| Ref : J Insect Sci , 23 :19 , 2023 |
| Abstract : Wang_2023_J.Insect.Sci_23_19 |
| ESTHER : Wang_2023_J.Insect.Sci_23_19 |
| PubMedSearch : Wang_2023_J.Insect.Sci_23_19 |
| PubMedID: 37578847 |
| Gene_locus related to this paper: 9acar-m9t420 |