HEPES

Component of many buffers and also found in many protein structures as a result of purification protocol

General

Type : Buffer Component,Piperazine,Sulfur Compound

Chemical_Nomenclature : 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid

Canonical SMILES : C1CN(CCN1CCO)CCS(=O)(=O)O

InChI : InChI=1S\/C8H18N2O4S\/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14\/h11H,1-8H2,(H,12,13,14)

InChIKey : JKMHFZQWWAIEOD-UHFFFAOYSA-N

Other name(s) : 2-(4-(2-Hydroxyethyl)piperazin-1-yl)ethanesulfonic acid,4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid,1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-,2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid


MW : 238.30

Formula : C8H18N2O4S

CAS_number : 7365-45-9

PubChem : 23831

UniChem : JKMHFZQWWAIEOD-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

Target

Families : HEPES ligand of proteins in family: Hormone-sensitive_lipase_like

Stucture :

Protein : aliac-est2 || lacpl-LP.2923

References (1)

Title : A snapshot of a transition state analogue of a novel thermophilic esterase belonging to the subfamily of mammalian hormone-sensitive lipase - De Simone_2000_J.Mol.Biol_303_761
Author(s) : De Simone G , Galdiero S , Manco G , Lang D , Rossi M , Pedone C
Ref : Journal of Molecular Biology , 303 :761 , 2000
Abstract : De Simone_2000_J.Mol.Biol_303_761
ESTHER : De Simone_2000_J.Mol.Biol_303_761
PubMedSearch : De Simone_2000_J.Mol.Biol_303_761
PubMedID: 11061974
Gene_locus related to this paper: aliac-est2