Hormone-sensitive_lipase_like

Relationship

Family: Hormone-sensitive_lipase_like

Block: H

Parent Family: No family

Comment

Sequence similarities between hormone-sensitive lipase and prokaryotic enzymes was dicovered by Langin and Holm and Hemila et al.. The family Corresponds to the Pfam entry Abhydrolase_3. For bacterial enzymes this family correspond to family IV of the classification of Arpigny et al 1999

Database

Interpro : IPR013094 Alpha\/beta hydrolase fold-3 , IPR002168 Lipolytic enzyme , IPR033140 Lipase_GDXG_put_SER_AS , IPR002168 Lipase_GDXG_HIS_AS

PIRSF : No PIRSF

Pdoc : PDOC00903

Pfam : PF07859 Abhydrolase_3

Prints : No Print

EC Number : No EC Number

Sequences

Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour
Alignment with MAFFT No colour
Dendrogram The dnd file

Structures (118)

Genes Proteins in Hormone-sensitive_lipase_like family (1632)

Fragments of genes in Hormone-sensitive_lipase_like family (67)

Structures in Hormone-sensitive_lipase_like family (118)

Substrates in Hormone-sensitive_lipase_like family (70)

Inhibitors in Hormone-sensitive_lipase_like family (41)

References (9)

Title : An overview of mammalian and microbial hormone-sensitive lipases (lipolytic family IV): biochemical properties and industrial applications - Nagaroor_2022_Biotechnol.Genet.Eng.Rev__1
Author(s) : Nagaroor V , Gummadi SN
Ref : Biotechnol Genet Eng Rev , :1 , 2022
PubMedID: 36154870

Title : Hormone-sensitive lipase: sixty years later - Recazens_2020_Prog.Lipid.Res__101084
Author(s) : Recazens E , Mouisel E , Langin D
Ref : Prog Lipid Res , :101084 , 2020
PubMedID: 33387571
Gene_locus related to this paper: human-LIPE

Title : Adipose Tissue Deficiency of Hormone-Sensitive Lipase Causes Fatty Liver in Mice - Xia_2017_PLoS.Genet_13_e1007110
Author(s) : Xia B , Cai GH , Yang H , Wang SP , Mitchell GA , Wu JW
Ref : PLoS Genet , 13 :e1007110 , 2017
PubMedID: 29232702
Gene_locus related to this paper: mouse-hslip

Title : Bacterial Hormone-Sensitive Lipases (bHSLs): Emerging Enzymes for Biotechnological Applications - Kim_2017_J.Microbiol.Biotechnol_27_1907
Author(s) : Kim TD
Ref : J Microbiol Biotechnol , 27 :1907 , 2017
PubMedID: 29032653

Title : Molecular cloning and characterization of a thermostable carboxylesterase from an archaeon, Sulfolobus shibatae DSM5389: non-linear kinetic behavior of a hormone-sensitive lipase family enzyme - Ejima_2004_J.Biosci.Bioeng_98_445
Author(s) : Ejima K , Liu J , Oshima Y , Hirooka K , Shimanuki S , Yokota Y , Hemmi H , Nakayama T , Nishino T
Ref : J Biosci Bioeng , 98 :445 , 2004
PubMedID: 16233734
Gene_locus related to this paper: sulsh-q5nu42

Title : Structure-function relationships of hormone-sensitive lipase - Osterlund_2001_Eur.J.Biochem_268_1899
Author(s) : Osterlund T
Ref : European Journal of Biochemistry , 268 :1899 , 2001
PubMedID: 11277912

Title : Molecular mechanisms regulating hormone-sensitive lipase and lipolysis - Holm_2000_Annu.Rev.Nutr_20_365
Author(s) : Holm C , Osterlund T , Laurell H , Contreras JA
Ref : Annu Rev Nutr , 20 :365 , 2000
PubMedID: 10940339

Title : Hormone-sensitive lipase is closely related to several bacterial proteins, and distantly related to acetylcholinesterase and lipoprotein lipase: identification of a superfamily of esterases and lipases - Hemila_1994_Biochim.Biophys.Acta_1210_249
Author(s) : Hemila H , Koivula TT , Palva I
Ref : Biochimica & Biophysica Acta , 1210 :249 , 1994
PubMedID: 8280778

Title : Sequence similarities between hormone-sensitive lipase and five prokaryotic enzymes -
Author(s) : Langin D , Holm C
Ref : Trends in Biochemical Sciences , 18 :466 , 1993
PubMedID: 8108858