DEFINITIONS biblio

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PaperTitleYear
Sanchez-Arroyo_2024_Appl.Microbiol.Biotechnol_108_230A new and promiscuous alpha/beta hydrolase from Acinetobacter tandoii DSM 14970( T) inactivates the mycotoxin ochratoxin A2024
Melville_2023_Curr.Biol__Perception of butenolides by Bacillus subtilis via the alpha/beta hydrolase RsbQ2023
Price_2023_PLoS.Genet_19_e1010713Lipidomic QTL in Diversity Outbred mice identifies a novel function for alpha/beta hydrolase domain 2 (Abhd2) as an enzyme that metabolizes phosphatidylcholine and cardiolipin2023
Price_2023_bioRxiv__Lipidomic QTL in Diversity Outbred mice identifies a novel function for alpha/beta hydrolase domain 2 (Abhd2) as an enzyme that metabolizes phosphatidylcholine and cardiolipin2023
Qiu_2023_Catalysts_13_288Recent Progress in the Mechanism and Engineering of alpha/beta Hydrolases for Chiral Chemical Production2023
Chatonnet_2023_Chem.Biol.Interact_14ChEPon_110671The ESTHER database on alpha/beta hydrolase fold proteins - An overview of recent developments2023
Kawai_2022_Chembiochem__The alpha/beta hydrolase AzpM catalyzes dipeptide synthesis in alazopeptin biosynthesis using two molecules of carrier protein-tethered amino acid2022
Schnettler-Fernandez_2022_Biorxiv__Ultrahigh-throughput directed evolution of a metal-free alpha/beta-hydrolase with a Cys-His-Asp triad into an efficient phosphotriesterase2022
Schnettler_2022_J.Am.Chem.Soc__Ultrahigh-Throughput Directed Evolution of a Metal-Free alpha/beta-Hydrolase with a Cys-His-Asp Triad into an Efficient Phosphotriesterase2022
Shan_2022_Int.J.Mol.Sci_23_alpha/beta-Hydrolase D16B Truncation Results in Premature Sperm Capacitation in Cattle2022
Pusch_2022_Metabolites_12_761alpha/beta-Hydrolase Domain-Containing 6 (ABHD6)- A Multifunctional Lipid Hydrolase2022
Shankar_2022_Int.J.Biol.Macromol_229_803Biochemical characterization, substrate and stereoselectivity of an outer surface putative alpha/beta hydrolase from the pathogenic Leptospira2022
Zong_2022_Nat.Commun_13_1449Mechanism and biomass association of glucuronoyl esterase: an alpha/beta hydrolase with potential in biomass conversion2022
Xiang_2022_Mol.Plant__An alpha/beta hydrolase family member negatively regulates salt tolerance but promotes flowering through three distinct functions in rice2022
Mardon_2022_J.Med.Chem__Utilizing PET and MALDI Imaging for Discovery of a Targeted Probe for Brain Endocannabinoid alpha/beta-Hydrolase Domain 6 (ABHD6)2022
Toyama_2022_Pharmaceutics_14_Gallic Acid as a Non-Selective Inhibitor of alpha/beta-Hydrolase Fold Enzymes Involved in the Inflammatory Process: The Two Sides of the Same Coin2022
Bzowka_2022_PLoS.Comput.Biol_18_e1010119Evolution of tunnels in alpha/beta-hydrolase fold proteins-What can we learn from studying epoxide hydrolases?2022
Ohta_2021_Environ.Microbiol__Degradation of ester linkages in rice straw components by Sphingobium species recovered from the sea bottom using a non-secretory tannase-family alpha/beta hydrolase2021
Gawarecka_2021_Plant.Cell.Environ__cis-Prenyltransferase 3 and alpha/beta-hydrolase are new determinants of dolichol accumulation in Arabidopsis2021
Bjorkgren_2021_Front.Cell.Dev.Biol_9_710864Alpha/Beta Hydrolase Domain-Containing Protein 2 regulates the rhythm of follicular maturation and estrous stages of the female reproductive cycle2021
Bononi_2021_J.Med.Chem_64_9759alpha/beta-Hydrolase Domain (ABHD) Inhibitors as New Potential Therapeutic Options against Lipid-Related Diseases2021
Zhang_2021_Front.Pharmacol_12_784202Alpha/Beta-Hydrolase Domain-Containing 6: Signaling and Function in the Central Nervous System2021
Noguchi_2021_Cannabis.Cannabinoid.Res__Phenotypic Characterization of the Endocannabinoid-Degrading Enzyme Alpha/Beta-Hydrolase Domain 6 Knockout Rat2021
Lagerman_2021_Chem.Eng.J_426_131816Kinetic model development for alpha-amino ester hydrolase (AEH)-catalyzed synthesis of beta-lactam antibiotics2021
Lu_2020_Front.Immunol_11_1388A Novel alpha/beta Hydrolase Domain Protein Derived From Haemonchus contortus Acts at the Parasite-Host Interface2020
Rayamajhi_2020_Biotechnol.Bioprocess.Eng_25_414Functional Characterization of NgnL, an Alpha/beta-hydrolase Enzyme Involved in Biosynthesis of Acetylated Nodusmicin2020
Sikandar_2020_Nat.Chem.Biol_16_1013The bottromycin epimerase BotH defines a group of atypical alpha/beta-hydrolase-fold enzymes2020
Wilkinson_2020_J.Struct.Biol__107496Extracellular alpha/beta-hydrolase from Paenibacillus species shares structural and functional homology to Tobacco Salicylic Acid Binding Protein 22020
Yoo_2020_Cell.Chem.Biol_27_143The Antimalarial Natural Product Salinipostin A Identifies Essential alpha/beta Serine Hydrolases Involved in Lipid Metabolism in P. falciparum Parasites2020
Shan_2020_Int.J.Mol.Sci_21_Association of alpha/beta-Hydrolase D16B with Bovine Conception Rate and Sperm Plasma Membrane Lipid Composition2020
Deng_2020_Eur.J.Med.Chem_198_112353Therapeutic potential of targeting alpha/beta-Hydrolase domain-containing 6 (ABHD6)2020
Zhang_2020_J.Biol.Chem_295_16987Mutation of an atypical oxirane oxyanion hole improves regioselectivity of the alpha/beta-fold epoxide hydrolase Alp1U2020
Wu_2020_Front.Bioeng.Biotechnol_8_844Effect of a Novel Alpha/Beta Hydrolase Domain Protein on Tolerance of K. marxianus to Lignocellulosic Biomass Derived Inhibitors2020
Wullich_2020_Appl.Environ.Microbiol__Definition of an alpha/beta-hydrolase fold subfamily comprising Pseudomonas quinolone signal cleaving dioxygenases2020
Ryu_2020_J.Microbiol.Biotechnol__Identification of a Second Type of AHL-lactonase from Rhodococcus sp. BH4, belonging to the alpha/beta Hydrolase Superfamily2020
Bauer_2020_FEBS.J_287_1035The modular structure of alpha/beta-hydrolases2020
Wu_2020_FASEB.J_34_1983Algorithm-based coevolution network identification reveals key functional residues of the alpha/beta hydrolase subfamilies2020
Garcia-Orozco_2019_Biomolecules_9_Biochemical Characterization of a Novel alpha/beta-Hydrolase/FSH from the White Shrimp Litopenaeus vannamei2019
Tian_2019_Toxins.(Basel)_11_CesH Represses Cereulide Synthesis as an Alpha/Beta Fold Hydrolase in Bacillus cereus2019
Hehlert_2019_J.Lipid.Res_60_1365The alpha/beta-hydrolase domain-containing 4- and 5-related phospholipase Pummelig controls energy storage in Drosophila2019
Bottemanne_2019_FASEB.J__fj201802259RThe alpha/beta-hydrolase domain 6 inhibitor WWL70 decreases endotoxin-induced lung inflammation in mice, potential contribution of 2-arachidonoylglycerol, and lysoglycerophospholipids2019
van Esbroeck_2019_Front.Mol.Neurosci_12_286Identification of alpha,beta-Hydrolase Domain Containing Protein 6 as a Diacylglycerol Lipase in Neuro-2a Cells2019
Shields_2019_Sci.Rep_9_890Biochemical and Proteomic Characterization of Recombinant Human alpha/beta Hydrolase Domain 62019
Ogasawara_2019_J.Med.Chem_62_1643Discovery and Optimization of Selective and in Vivo Active Inhibitors of the Lysophosphatidylserine Lipase alpha/beta-Hydrolase Domain-Containing 12 (ABHD12)2019
Wullich_2019_J.Struct.Biol_207_287Structural basis for recognition and ring-cleavage of the Pseudomonas quinolone signal (PQS) by AqdC, a mycobacterial dioxygenase of the alpha/beta-hydrolase fold family2019
Dimitriou_2019_Protein.Sci_28_344Distinctive structural motifs co-ordinate the catalytic nucleophile and the residues of the oxyanion hole in the alpha/beta-hydrolase fold enzymes2019
Ferrandi_2018_Front.Bioeng.Biotechnol_6_144New Thermophilic alpha/beta Class Epoxide Hydrolases Found in Metagenomes From Hot Environments2018
Rangasamy_2018_Biomed.Res.Int_2018_1535209Cloning and Expression of the Organophosphate Pesticide-Degrading alpha-beta Hydrolase Gene in Plasmid pMK-07 to Confer Cross-Resistance to Antibiotics2018
Divya_2018_Prog.Biophys.Mol.Biol_140_90Mycobacterium tuberculosis PE1 and PE2 proteins carrying conserved alpha/beta-serine hydrolase domain are esterases hydrolyzing short to medium chain p-nitrophenyl esters2018
Paye_2018_Anal.Biochem_549_80A high-throughput pH-based colorimetric assay: application focus on alpha/beta hydrolases2018
van Rooden_2018_Chem.Asian.J_13_3491Design and Synthesis of Quenched Activity-based Probes for Diacylglycerol Lipase and alpha,beta-Hydrolase Domain Containing Protein 62018
Zheng_2018_FASEB.J_32_527The JAVA Based Computational Tool for Pairwise Comparison of Protein Backbone Folds in Liganded and Apo 3D Structures of the alpha/beta Hydrolase Fold Proteins2018
Brown_2017_Biochim.Biophys.Acta_1862_1233Critical roles for alpha/beta hydrolase domain 5 (ABHD5)/comparative gene identification-58 (CGI-58) at the lipid droplet interface and beyond2017
Arya_2017_Biochem.Biophys.Res.Commun_487_875Human alpha beta hydrolase domain containing protein 11 and its yeast homolog are lipid hydrolases2017
Jones_2017_Biochemistry_56_6521Comparison of Five Protein Engineering Strategies for Stabilizing an alpha/beta-Hydrolase2017
Singh_2017_Protein.Eng.Des.Sel_30_559Role of an N-terminal extension in stability and catalytic activity of a hyperthermostable alpha/beta hydrolase fold esterase2017
Wei_2017_Front.Mol.Neurosci_10_55The Inhibitory Effect of alpha/beta-Hydrolase Domain-Containing 6 (ABHD6) on the Surface Targeting of GluA2- and GluA3-Containing AMPA Receptors2017
Dimitriou_2017_Proteins_85_1845Alpha/beta-hydrolases: A unique structural motif coordinates catalytic acid residue in 40 protein fold families2017
Kuatsjah_2017_J.Biol.Chem_292_18290The bacterial meta-cleavage hydrolase LigY belongs to the amidohydrolase superfamily, not to the alpha/beta-hydrolase superfamily2017
Bourne_2017_Molecules_22_Hot Spots for Protein Partnerships at the Surface of Cholinesterases and Related alpha/beta Hydrolase Fold Proteins or Domains-A Structural Perspective2017
Tolzer_2016_FEBS.Lett_590_174A novel esterase subfamily with alpha/beta-hydrolase fold suggested by structures of two bacterial enzymes homologous to l-homoserine O-acetyl transferases2016
Li_2016_J.Mol.Catal.B.Enzym_125_75Rational selection of circular permutation sites in characteristic regions of the alpha/beta-hydrolase fold enzyme RhEst12016
Shi_2016_Biochemistry_55_6705An Atypical alpha/beta-Hydrolase Fold Revealed in the Crystal Structure of Pimeloyl-Acyl Carrier Protein Methyl Esterase BioG from Haemophilus influenzae2016
Zhao_2016_Cell.Rep_14_2872alpha/beta-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes2016
Wei_2016_Proc.Natl.Acad.Sci.U.S.A_113_E2695alpha/beta-Hydrolase domain-containing 6 (ABHD6) negatively regulates the surface delivery and synaptic function of AMPA receptors2016
Fisette_2016_Cell.Rep_17_1217alpha/beta-Hydrolase Domain 6 in the Ventromedial Hypothalamus Controls Energy Metabolism Flexibility2016
Navia-Paldanius_2016_Eur.J.Pharm.Sci_93_253Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human alpha/beta-hydrolase domain containing 11 (ABHD11)2016
Johnson_2017_Curr.Protein.Pept.Sci_18_190The alpha/beta Hydrolase Fold Proteins of Mycobacterium tuberculosis, With Reference to their Contribution to Virulence2016
Zheng_2016_Proc.Natl.Acad.Sci.U.S.A_113_14318An alpha/beta-hydrolase fold protein in the biosynthesis of thiostrepton exhibits a dual activity for endopeptidyl hydrolysis and epoxide ring opening/macrocyclization2016
Mindrebo_2016_Curr.Opin.Struct.Biol_41_233Unveiling the functional diversity of the alpha/beta hydrolase superfamily in the plant kingdom2016
Lenfant_2016_Chem.Biol.Interact_259_343Relationships of human alpha/beta hydrolase fold proteins and other organophosphate-interacting proteins2016
Groat-Carmona_2015_Cell.Microbiol_17_1848A Plasmodium alpha/beta-hydrolase modulates the development of invasive stages2015
Waters_2015_Mol.Plant_8_814Substrate-Induced Degradation of the alpha/beta-Fold Hydrolase KARRIKIN INSENSITIVE2 Requires a Functional Catalytic Triad but Is Independent of MAX22015
Pribasnig_2015_J.Biol.Chem_290_29869alpha/beta Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate2015
Zhao_2015_Mol.Metab_4_940alpha/beta-Hydrolase domain-6 and saturated long chain monoacylglycerol regulate insulin secretion promoted by both fuel and non-fuel stimuli2015
Huang_2015_Biochemistry_54_4330Stabilization of an alpha/beta-Hydrolase by Introducing Proline Residues: Salicylic Acid Binding Protein 2 from Tobacco2015
Kaczor_2015_J.Mol.Model_21_2789Comparative molecular field analysis and molecular dynamics studies of alpha/beta hydrolase domain containing 6 (ABHD6) inhibitors2015
Jimenez_2015_Microb.Biotechnol_8_604Compositional profile of alpha / beta-hydrolase fold proteins in mangrove soil metagenomes: prevalence of epoxide hydrolases and haloalkane dehalogenases in oil-contaminated sites2015
Rauwerdink_2015_ACS.Catal_5_6153How the Same Core Catalytic Machinery Catalyzes 17 Different Reactions: the Serine-Histidine-Aspartate Catalytic Triad of alpha/beta-Hydrolase Fold Enzymes2015
Liu_2014_PLoS.One_9_e115128A Novel alpha/beta-Hydrolase Gene IbMas Enhances Salt Tolerance in Transgenic Sweetpotato2014
Chevalier_2014_Plant.Cell_26_1134Strigolactone promotes degradation of DWARF14, an alpha/beta hydrolase essential for strigolactone signaling in Arabidopsis2014
Sun_2014_J.Biol.Chem_289_15867Molecular Basis of the General Base Catalysis of an alpha/beta-Hydrolase Catalytic Triad2014
Nedrud_2014_Chem.Sci_5_4265Uncovering divergent evolution of alpha/beta-hydrolases: a surprising residue substitution needed to convert hydroxynitrile lyase into an esterase2014
Thomas_2014_Biochim.Biophys.Acta_1841_1097In vivo metabolite profiling as a means to identify uncharacterized lipase function: Recent success stories within the alpha beta hydrolase domain (ABHD) enzyme family2014
McMahon_2014_J.Lipid.Res_55_1750Comparative gene identification 58/alpha/beta hydrolase domain 5 lacks lysophosphatidic acid acyltransferase activity2014
Parkkari_2014_PLoS.One_9_e98286Discovery of Triterpenoids as Reversible Inhibitors of alpha/beta-hydrolase Domain Containing 12 (ABHD12)2014
Alvarez_2014_PLoS.One_9_e92257Esterase LpEst1 from Lactobacillus plantarum: A Novel and Atypical Member of the alphabeta Hydrolase Superfamily of Enzymes2014
Wang_2014_Proteins_82_695Structural and functional characterization of a novel alpha/beta hydrolase from cariogenic pathogen Streptococcus mutans2014
Kaljunen_2014_Acta.Crystallogr.F.Struct.Biol.Commun_70_1394Cloning, expression, purification and preliminary X-ray analysis of EstN2, a novel archaeal alpha/beta-hydrolase from Candidatus Nitrososphaera gargensis2014
Janssen_2014_J.Med.Chem_57_6610Discovery of Glycine Sulfonamides as Dual Inhibitors of sn-1-Diacylglycerol Lipase alpha and alpha/beta-Hydrolase Domain 62014
Zierler_2014_Curr.Opin.Lipidol_25_102Comparative gene identification-58/alpha/beta hydrolase domain 5: more than just an adipose triglyceride lipase activator?2014
Zhao_2014_Cell.Metab_19_993alpha/beta-Hydrolase domain-6-accessible monoacylglycerol controls glucose-stimulated insulin secretion2014
Alcaide_2013_Biochem.J_454_157Single residues dictate the co-evolution of dual esterases: MCP hydrolases from the alpha/beta hydrolase family2013
Park_2013_Plant.Cell_25_1726The alpha/beta hydrolase CGI-58 and peroxisomal transport protein PXA1 Coregulate lipid homeostasis and signaling in Arabidopsis2013
Walenta_2013_PLoS.One_8_e79134alpha/beta-Hydrolase Domain Containing Protein 15 (ABHD15) - an Adipogenic Protein Protecting from Apoptosis2013
Zhao_2013_Cell.Res_23_436Crystal structures of two phytohormone signal-transducing alpha/beta hydrolases: karrikin-signaling KAI2 and strigolactonesignaling DWARF142013
Hsu_2013_J.Med.Chem_56_8270Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of alpha/beta-hydrolase domain containing 6 (ABHD6)2013
Guo_2013_Proc.Natl.Acad.Sci.U.S.A_110_8284Smoke-derived karrikin perception by the alpha/beta-hydrolase KAI2 from Arabidopsis2013
Tchantchou_2013_J.Neurotrauma_30_565Selective inhibition of alpha/beta-hydrolase domain 6 attenuates neurodegeneration, alleviates blood brain barrier breakdown, and improves functional recovery in a mouse model of traumatic brain injury2013
Lenfant_2013_Nucleic.Acids.Res_41_D423ESTHER, the database of the alpha/beta-hydrolase fold superfamily of proteins: tools to explore diversity of functions2013
Procopio_2013_Antonie.Van.Leeuwenhoek_103_635The putative alpha/beta-hydrolases of Dietzia cinnamea P4 strain as potential enzymes for biocatalytic applications2013
Lenfant_2013_Chem.Biol.Interact_203_266Proteins with an alpha/beta hydrolase fold: Relationships between subfamilies in an ever-growing superfamily2013
Lord_2013_Biochim.Biophys.Acta_1831_792Mammalian alpha beta hydrolase domain (ABHD) proteins: Lipid metabolizing enzymes at the interface of cell signaling and energy metabolism2013
Andexer_2012_Chembiochem_13_1932Hydroxynitrile lyases with alpha/beta-hydrolase fold: two enzymes with almost identical 3D structures but opposite enantioselectivities and different reaction mechanisms2012
Suplatov_2012_Protein.Eng.Des.Sel_25_689Bioinformatic analysis of alpha/beta-hydrolase fold enzymes reveals subfamily-specific positions responsible for discrimination of amidase and lipase activities2012
Simpson_2012_Apoptosis_17_666A genome wide shRNA screen identifies alpha/beta hydrolase domain containing 4 (ABHD4) as a novel regulator of anoikis resistance2012
Lord_2012_Adipocyte_1_123Distinct roles for alpha-beta hydrolase domain 5 (ABHD5/CGI-58) and adipose triglyceride lipase (ATGL/PNPLA2) in lipid metabolism and signaling2012
Navia-Paldanius_2012_J.Lipid.Res_53_2413Biochemical and pharmacological characterization of human alpha/beta-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12)2012
Iwamura_2012_J.Biol.Chem_287_9240Human alpha/beta hydrolase domain containing 10 (ABHD10) is responsible enzyme for deglucuronidation of mycophenolic acid acyl-glucuronide in liver2012
Hamiaux_2012_Curr.Biol_22_2032DAD2 Is an alpha/beta Hydrolase Likely to Be Involved in the Perception of the Plant Branching Hormone, Strigolactone2012
Bahl_2012_Protein.Pept.Lett_19_186Pseudomonas aeruginosa Cif defines a distinct class of alpha/beta epoxide hydrolases utilizing a His/Tyr ring-opening pair2012
Auldridge_2012_Plant.Cell_24_1596Emergent decarboxylase activity and attenuation of alpha/beta-hydrolase activity during the evolution of methylketone biosynthesis in tomato2012
De Jaco_2012_Febs.J_279_4293Congenital hypothyroidism mutations affect common folding and trafficking in the alpha/beta-hydrolase fold proteins2012
Knapik_2012_Proteins_80_2359A multi-faceted analysis of RutD reveals a novel family of alpha/beta hydrolases2012
Zhou_2012_Acta.Biochim.Biophys.Sin.(Shanghai)_44_965Alteration of substrate specificities of thermophilic alpha/beta hydrolases through domain swapping and domain interface optimization2012
De Jaco_2012_Protein.Pept.Lett_19_173Processing of cholinesterase-like alpha/beta-hydrolase fold proteins: alterations associated with congenital disorders2012
Marchot_2012_Protein.Pept.Lett_19_132Enzymatic activity and protein interactions in alpha/beta hydrolase fold proteins: moonlighting versus promiscuity2012
Marchot_2012_Protein.Pept.Lett_19_130Hydrolase versus other functions of members of the alpha/beta-hydrolase fold superfamily of proteins2012
Nadezhdin_2011_PLoS.One_6_e25418An alpha/beta hydrolase and associated Per-ARNT-Sim domain comprise a bipartite sensing module coupled with diverse output domains2011
Jochens_2011_Chembiochem_12_1508Protein engineering of alpha/beta-hydrolase fold enzymes2011
Marrs_2011_J.Biol.Chem_286_28723Dual inhibition of alpha/beta-hydrolase domain 6 and fatty acid amide hydrolase increases endocannabinoid levels in neurons2011
Martinez_2011_FEMS.Microbiol.Lett_314_57Regulation and structure of YahD, a copper-inducible alpha/beta serine hydrolase of Lactococcus lactis IL14032011
Sultana_2011_PLoS.ONE_6_e16745The PE-PPE domain in mycobacterium reveals a serine alpha/beta hydrolase fold and function: an in-silico analysis2011
Thoms_2011_J.Struct.Biol_175_362The unusual extended C-terminal helix of the peroxisomal alpha/beta-hydrolase Lpx1 is involved in dimer contacts but dispensable for dimerization2011
Adibekian_2011_Probe.Report__1Optimization and characterization of a triazole urea inhibitor for alpha/beta hydrolase domain-containing protein 11 (ABHD11): anti-probe for LYPLA1/LYPLA2 dual inhibitor ML2112011
Lazniewski_2011_FEBS.Lett_585_870Novel transmembrane lipases of alpha/beta hydrolase fold2011
Mei_2010_Appl.Environ.Microbiol_76_4933AidH, an alpha/beta-hydrolase fold family member from an Ochrobactrum sp. strain, is a novel N-acylhomoserine lactonase2010
Steiner_2010_Proc.Natl.Acad.Sci.U.S.A_107_657Structural basis for cofactor-independent dioxygenation of N-heteroaromatic compounds at the alpha/beta-hydrolase fold2010
Rid_2010_Mol.Immunol_47_1366Isolation and immunological characterization of a novel Cladosporium herbarum allergen structurally homologous to the alpha/beta hydrolase fold superfamily2010
De Jaco_2010_Chem.Biol.Interact_187_56Folding anomalies of neuroligin3 caused by a mutation in the alpha/beta-hydrolase fold domain2010
Leone_2010_Chem.Biol.Interact_187_49Structure-function relationships of the alpha/beta-hydrolase fold domain of neuroligin: a comparison with acetylcholinesterase2010
Yamaguchi_2010_Biol.Pharm.Bull_33_342Crucial role of CGI-58/alpha/beta hydrolase domain-containing protein 5 in lipid metabolism2010
De Jaco_2010_J.Biol.Chem_285_28674Neuroligin trafficking deficiencies arising from mutations in the alpha/beta-hydrolase fold protein family2010
Kourist_2010_Chembiochem_11_1635The alpha/beta-hydrolase fold 3DM database (ABHDB) as a tool for protein engineering2010
Guterl_2009_J.Biotechnol_141_166Uneven twins: comparison of two enantiocomplementary hydroxynitrile lyases with alpha/beta-hydrolase fold2009
Skjot_2009_Chembiochem_10_520Understanding the plasticity of the alpha/beta hydrolase fold: lid swapping on the Candida antarctica lipase B results in chimeras with interesting biocatalytic properties2009
Stoelting_2009_Biochem.Biophys.Res.Commun_379_81Alpha/beta hydrolase 1 is upregulated in D5 dopamine receptor knockout mice and reduces O2- production of NADPH oxidase2009
Jin_2009_Biochem.Biophys.Res.Commun_380_419Age-related pulmonary emphysema in mice lacking alpha/beta hydrolase domain containing 2 gene2009
Max_2009_Cancer.Sci_100_2383High expression of the evolutionarily conserved alpha/beta hydrolase domain containing 6 (ABHD6) in Ewing tumors2009
Li_2009_Mol.Biol.Rep_36_691An unannotated alpha/beta hydrolase superfamily member, ABHD6 differentially expressed among cancer cell lines2009
Morita_2009_Plant.J_59_940Defect in non-yellow coloring 3, an alpha/beta hydrolase-fold family protein, causes a stay-green phenotype during leaf senescence in rice2009
Carr_2009_Protein.Pept.Lett_16_1137Alpha/beta hydrolase fold: an update2009
Li_2008_Chembiochem_9_71Catalytic promiscuity in the alpha/beta-hydrolase superfamily: hydroxamic acid formation, C--C bond formation, ester and thioester hydrolysis in the C--C hydrolase family2008
Merritt_2008_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_64_474Structure of a Trypanosoma brucei alpha/beta-hydrolase fold protein with unknown function2008
Qin_2008_Invest.Ophthalmol.Vis.Sci_49_1274Implication of S-adenosylhomocysteine hydrolase in inhibition of TNF-alpha- and IL-1beta-induced expression of inflammatory mediators by AICAR in RPE cells2008
Akiyama_2008_Am.J.Pathol_173_1349CGI-58 is an alpha/beta-hydrolase within lipid transporting lamellar granules of differentiated keratinocytes2008
Andexer_2007_Angew.Chem.Int.Ed.Engl_46_8679An R-selective hydroxynitrile lyase from Arabidopsis thaliana with an alpha/beta-hydrolase fold2007
Schleberger_2007_J.Mol.Biol_367_409Structure and action of a C-C bond cleaving alpha/beta-hydrolase involved in nicotine degradation2007
Steiner_2007_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_63_382Crystallization and preliminary X-ray analysis of 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase from Arthrobacter nitroguajacolicus Ru61a: a cofactor-devoid dioxygenase of the alpha/beta-hydrolase-fold superfamily2007
Hikage_2007_Mol.Genet.Genomics_278_95Structure and allele-specific expression variation of novel alpha/beta hydrolase fold proteins in gentian plants2007
Xie_2007_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_63_993Structure of the minimized alpha/beta-hydrolase fold protein from Thermus thermophilus HB82007
Qi_2007_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_63_378Crystallization and diffraction data of 1H-3-hydroxy-4-oxoquinoline 2,4-dioxygenase: a cofactor-free oxygenase of the alpha/beta-hydrolase family2007
Qian_2007_Biotechnol.J_2_192Recent progress in engineering alpha/beta hydrolase-fold family members2007
Fischer_2007_Med.Sci.(Paris)_23_575[Neutral lipid storage diseases and ATGL (adipose triglyceride lipase) and CGI-58/ABHD5 (alpha-beta hydrolase domain-containing 5) deficiency: myopathy, ichthyosis, but no obesity]2007
Li_2007_Org.Biomol.Chem_5_507Investigation of a general base mechanism for ester hydrolysis in C-C hydrolase enzymes of the alpha/beta-hydrolase superfamily: a novel mechanism for the serine catalytic triad2007
Kolkenbrock_2006_J.Bacteriol_188_8430N-acetylanthranilate amidase from Arthrobacter nitroguajacolicus Ru61a, an alpha/beta-hydrolase-fold protein active towards aryl-acylamides and -esters, and properties of its cysteine-deficient variant2006
Yau_2006_FEBS.Lett_580_1465J1 acylase, a glutaryl-7-aminocephalosporanic acid acylase from Bacillus laterosporus J1, is a member of the alpha/beta-hydrolase fold superfamily2006
Simon_2006_J.Biol.Chem_281_26465Endocannabinoid biosynthesis proceeding through glycerophospho-N-acyl ethanolamine and a role for alpha/beta-hydrolase 4 in this pathway2006
Yang_2006_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_62_498Structure of XC6422 from Xanthomonas campestris at 1.6 A resolution: a small serine alpha/beta-hydrolase2006
De Jaco_2006_J.Biol.Chem_281_9667A mutation linked with autism reveals a common mechanism of endoplasmic reticulum retention for the alpha,beta-hydrolase fold protein family2006
Sachelaru_2005_J.Bacteriol_187_8516An alpha/beta-fold C--C bond hydrolase is involved in a central step of nicotine catabolism by Arthrobacter nicotinovorans2005
Bourne_2005_Chem.Biol.Interact_157-158_395A. niger protein EstA, perhaps a new electrotactin, defines a new class of fungal esterases within the alpha/beta hydrolase fold superfamily2005
Mirza_2005_Biochemistry_44_15768Crystal structure of homoserine transacetylase from Haemophilus influenzae reveals a new family of alpha/beta-hydrolases2005
Miyata_2005_Biochem.Biophys.Res.Commun_329_296Increase of smooth muscle cell migration and of intimal hyperplasia in mice lacking the alpha/beta hydrolase domain containing 2 gene2005
Elmi_2005_J.Bacteriol_187_8470Stereoselective esterase from Pseudomonas putida IFO12996 reveals alpha/beta hydrolase folds for D-beta-acetylthioisobutyric acid synthesis2005
Murayama_2005_Proteins_58_982Crystal structure of TT1662 from Thermus thermophilus HB8: a member of the alpha/beta hydrolase fold enzymes2005
Arndt_2005_Proteins_58_755Crystal structure of an alpha/beta serine hydrolase (YDR428C) from Saccharomyces cerevisiae at 1.85 A resolution2005
De Jaco_2005_Chem.Biol.Interact_157-158_371A single mutation near the C-terminus in alpha/beta hydrolase fold protein family causes a defect in protein processing2005
Zheng_2005_Proteins_59_1Protein domain of unknown function DUF1023 is an alpha/beta hydrolase2005
Siew_2005_FEBS.Lett_579_3175A putative novel alpha/beta hydrolase ORFan family in Bacillus2005
Renault_2005_Chem.Biol.Interact_157-158_339New friendly tools for users of ESTHER, the database of the alpha/beta-hydrolase fold superfamily of proteins2005
Koschorreck_2005_BMC.Genomics_6_49How to find soluble proteins: a comprehensive analysis of alpha/beta hydrolases for recombinant expression in E. coli2005
Bourne_2004_Structure_12_677Aspergillus niger protein EstA defines a new class of fungal esterases within the alpha/beta hydrolase fold superfamily of proteins2004
Gruber_2004_J.Biol.Chem_279_20501Reaction mechanism of hydroxynitrile lyases of the alpha/beta-hydrolase superfamily: the three-dimensional structure of the transient enzyme-substrate complex certifies the crucial role of LYS2362004
Wilson_2004_J.Mol.Biol_335_519The structure of Mycobacterium tuberculosis MPT51 (FbpC1) defines a new family of non-catalytic alpha/beta hydrolases2004
Hotelier_2004_Nucleic.Acids.Res_32_D145ESTHER, the database of the alpha/beta-hydrolase fold superfamily of proteins2004
Chatonnet_2004_7th.ChE.Meeting.Pucon__75Evolution of the Carboxylcsterase_b (CO esterase) family: The closest relatives of choIinesterases among alpha/beta hydrolase fold family. hypothesis of horizontal transfer from eucaryotes to bacteria2004
Wisotzkey_2003_J.Mol.Evol_56_351Alpha/beta hydrolase2, a predicated gene adjacent to mad in Drosophila melanogaster, belongs to a new global multigene family and is associated with obesity2003
Bhaduri_2003_J.Mol.Model_9_3Fold prediction and comparative modeling of Bdm1: a probable alpha/beta hydrolase associated with hot water epilepsy2003
De Mot_2003_FEMS.Microbiol.Lett_224_197The thiocarbamate-inducible Rhodococcus enzyme ThcF as a member of the family of alpha/beta hydrolases with haloperoxidative side activity2003
Nagy_2003_J.Bacteriol_185_496Characterization of a novel intracellular endopeptidase of the alpha/beta hydrolase family from Streptomyces coelicolor A3(2)2003
Barends_2003_J.Biol.Chem_278_23076The sequence and crystal structure of the alpha -amino acid ester hydrolase from Xanthomonas citri define a new family of beta -lactam antibiotic acylases2003
Edgar_2002_Biochem.Biophys.Res.Commun_292_617Cloning and tissue distribution of three murine alpha/beta hydrolase fold protein cDNAs2002
Shaw_2002_Proteins_47_163Identification of a novel class in the alpha/beta hydrolase fold superfamily: the N-myc differentiation-related proteins2002
van Pouderoyen_2001_J.Mol.Biol_309_215The crystal structure of Bacillus subtilis lipase: a minimal alpha/beta hydrolase fold enzyme2001
Brody_2001_J.Bacteriol_183_6422Catalytic function of an alpha/beta hydrolase is required for energy stress activation of the sigma(B) transcription factor in Bacillus subtilis2001
Huhtinen_2001_J.Biol.Chem_277_3424The peroxisome proliferator-induced cytosolic type I acyl-CoA thioesterase (CTE-I) is a serine-histidine-aspartic acid alpha/beta hydrolase2001
Chatonnet_2001_Brief.Bioinform_2_30Links between kinetic data and sequences in the alpha/beta-hydrolases fold database2001
Edgar_2000_J.Anat_197_320LABH-1: cloning of a novel alpha/beta hydrolase fold protein from mouse lung in Proceedings of the Anatomical Society of Great Britain and Ireland2000
Dogru_2000_Eur.J.Biochem_267_1397The gene encoding polyneuridine aldehyde esterase of monoterpenoid indole alkaloid biosynthesis in plants is an ortholog of the alpha/betahydrolase super family2000
Holmquist_2000_Curr.Protein.Pept.Sci_1_209Alpha/Beta-hydrolase fold enzymes: structures, functions and mechanisms2000
Fischer_1999_J.Bacteriol_181_5725Bacterial 2,4-dioxygenases: new members of the alpha/beta hydrolase-fold superfamily of enzymes functionally related to serine hydrolases1999
Morel_1999_Biochim.Biophys.Acta_1429_501The prolyl aminopeptidase from Lactobacillus delbrueckii subsp. bulgaricus belongs to the alpha/beta hydrolase fold family1999
Heikinheimo_1999_Structure.Fold.Des_7_R141Of barn owls and bankers: a lush variety of alpha/beta hydrolases1999
Nardini_1999_Curr.Opin.Struct.Biol_9_732Alpha/beta hydrolase fold enzymes: the family keeps growing1999
Chatonnet_1999_Chem.Biol.Interact_119-120_567Kinetic parameters of cholinesterase interactions with organophosphates: retrieval and comparison tools available through ESTHER database: ESTerases, alpha/beta Hydrolase Enzymes and Relatives1999
Waspi_1998_Eur.J.Biochem_254_32The defense-related rice gene Pir7b encodes an alpha/beta hydrolase fold protein exhibiting esterase activity towards naphthol AS-esters1998
Zhang_1998_Fold.Des_3_535Functional analysis of the Escherichia coli genome for members of the alpha/beta hydrolase family1998
Derewenda_1998_6th.ChE.Meeting.San.Diego__309Structure-Function Relationships in High Molecular Weight PAF-Acetylhydrolases from the Studies of a Microbial alpha/beta Hydrolase1998
Watanabe_1998_Biochim.Biophys.Acta_1401_73Molecular cloning of cDNAs encoding alpha1, alpha2, and beta subunits of rat brain platelet-activating factor acetylhydrolase1998
Kim_1997_Structure_5_1571Crystal structure of carboxylesterase from Pseudomonas fluorescens, an alpha/beta hydrolase with broad substrate specificity1997
Schrag_1997_Methods.Enzymol_284_85Lipases and alpha/beta hydrolase fold1997
Cousin_1997_Nucleic.Acids.Res_25_143The alpha/beta hydrolase fold family of proteins database and the cholinesterase gene server ESTHER1997
Hisano_1996_J.Biol.Chem_271_20322Crystal structure of L-2-haloacid dehalogenase from Pseudomonas sp. YL. An alpha/beta hydrolase structure that is different from the alpha/beta hydrolase fold1996
Goossens_1995_Eur.J.Biochem_233_432The purification, characterization and analysis of primary and secondary-structure of prolyl oligopeptidase from human lymphocytes. Evidence that the enzyme belongs to the alpha/beta hydrolase fold family1995
Diaz_1995_J.Biol.Chem_270_6403Identification of functional residues in a 2-hydroxymuconic semialdehyde hydrolase. A new member of the alpha/beta hydrolase-fold family of enzymes which cleaves carbon-carbon bonds1995
Cousin_1995_5th.ChE.Meeting.Madras__489A Database of Sequences Related to AcetylcholinesteraselLipase/alpha:beta Hydrolase Superfamily with Public Access on Internet1995
Hecht_1994_Nat.Struct.Biol_1_532The metal-ion-free oxidoreductase from Streptomyces aureofaciens has an alpha/beta hydrolase fold1994
Mortensen_1994_Protein.Sci_3_838A conserved glutamic acid bridge in serine carboxypeptidases, belonging to the alpha/beta hydrolase fold, acts as a pH-dependent protein-stabilizing element1994
Ollis_1992_Prot.Engin_5_197The alpha/beta hydrolase fold1992