Family_I.8

General

ESTHER family : Bacterial_lip_FamI.8

Comment :
This family corresponds to family I.6 of the classification of Arpigny and Jaeger (1999). These lipases differ from other bacterial lipases but groups putative psychrophilic esterases/lipases. The closest family is CarbLipBact_2. Features of the new family include: a conserved new active-site pentapeptide motif (LGG(F/L/Y)STG); the likely extra-cytoplasmic localization; the absence of a typical calcium-binding pocket; and the absence of a canonical lid.

References (1)

Title : The cold-active Lip1 lipase from the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125 is a member of a new bacterial lipolytic enzyme family - de Pascale_2008_Extremophiles_12_311
Author(s) : de Pascale D , Cusano AM , Autore F , Parrilli E , di Prisco G , Marino G , Tutino ML
Ref : Extremophiles , 12 :311 , 2008
Abstract : de Pascale_2008_Extremophiles_12_311
ESTHER : de Pascale_2008_Extremophiles_12_311
PubMedSearch : de Pascale_2008_Extremophiles_12_311
PubMedID: 18437283
Gene_locus related to this paper: pseht-q3if07