Bugg TD

References (15)

Title : Merging Plastics, Microbes, and Enzymes: Highlights from an International Workshop - Jimenez_2022_Appl.Environ.Microbiol_88_e0072122
Author(s) : Jimenez DJ , Ozturk B , Wei R , Bugg TD , Amaya Gomez CV , Salcedo Galan F , Castro-Mayorga JL , Saldarriaga JF , Tarazona NA
Ref : Applied Environmental Microbiology , 88 :e0072122 , 2022
Abstract :
PubMedSearch : Jimenez_2022_Appl.Environ.Microbiol_88_e0072122
PubMedID: 35762791

Title : Catalytic promiscuity in the alpha\/beta-hydrolase superfamily: hydroxamic acid formation, C--C bond formation, ester and thioester hydrolysis in the C--C hydrolase family - Li_2008_Chembiochem_9_71
Author(s) : Li C , Hassler M , Bugg TD
Ref : Chembiochem , 9 :71 , 2008
Abstract :
PubMedSearch : Li_2008_Chembiochem_9_71
PubMedID: 18058773
Gene_locus related to this paper: ecoli-mhpc

Title : Investigation of a general base mechanism for ester hydrolysis in C-C hydrolase enzymes of the alpha\/beta-hydrolase superfamily: a novel mechanism for the serine catalytic triad - Li_2007_Org.Biomol.Chem_5_507
Author(s) : Li JJ , Bugg TD
Ref : Org Biomol Chem , 5 :507 , 2007
Abstract :
PubMedSearch : Li_2007_Org.Biomol.Chem_5_507
PubMedID: 17252134

Title : Catalytic role for arginine 188 in the C-C hydrolase catalytic mechanism for Escherichia coli MhpC and Burkholderia xenovorans LB400 BphD - Li_2006_Biochemistry_45_12470
Author(s) : Li C , Li JJ , Montgomery MG , Wood SP , Bugg TD
Ref : Biochemistry , 45 :12470 , 2006
Abstract :
PubMedSearch : Li_2006_Biochemistry_45_12470
PubMedID: 17029402

Title : Evidence for a gem-diol reaction intermediate in bacterial C-C hydrolase enzymes BphD and MhpC from 13C NMR spectroscopy - Li_2006_Biochemistry_45_12461
Author(s) : Li JJ , Li C , Blindauer CA , Bugg TD
Ref : Biochemistry , 45 :12461 , 2006
Abstract :
PubMedSearch : Li_2006_Biochemistry_45_12461
PubMedID: 17029401

Title : Stereochemistry of the reaction catalysed by 2-hydroxy-6-keto-6-phenyl-hexa-2,4-dienoic acid 5,6-hydrolase (BphD) - Li_2005_Chem.Commun.(Camb)__130
Author(s) : Li JJ , Bugg TD
Ref : Chem Commun (Camb) , :130 , 2005
Abstract :
PubMedSearch : Li_2005_Chem.Commun.(Camb)__130
PubMedID: 15614396

Title : Catalytic mechanism of C-C hydrolase MhpC from Escherichia coli: kinetic analysis of His263 and Ser110 site-directed mutants - Li_2005_J.Mol.Biol_346_241
Author(s) : Li C , Montgomery MG , Mohammed F , Li JJ , Wood SP , Bugg TD
Ref : Journal of Molecular Biology , 346 :241 , 2005
Abstract :
PubMedSearch : Li_2005_J.Mol.Biol_346_241
PubMedID: 15663941
Gene_locus related to this paper: ecoli-mhpc

Title : The structure of the C-C bond hydrolase MhpC provides insights into its catalytic mechanism - Dunn_2005_J.Mol.Biol_346_253
Author(s) : Dunn G , Montgomery MG , Mohammed F , Coker A , Cooper JB , Robertson T , Garcia JL , Bugg TD , Wood SP
Ref : Journal of Molecular Biology , 346 :253 , 2005
Abstract :
PubMedSearch : Dunn_2005_J.Mol.Biol_346_253
PubMedID: 15663942
Gene_locus related to this paper: ecoli-mhpc

Title : Synthetic 6-aryl-2-hydroxy-6-ketohexa-2,4-dienoic acid substrates for C-C hydrolase BphD: investigation of a general base catalytic mechanism - Speare_2004_Org.Biomol.Chem_2_2942
Author(s) : Speare DM , Fleming SM , Beckett MN , Li JJ , Bugg TD
Ref : Org Biomol Chem , 2 :2942 , 2004
Abstract :
PubMedSearch : Speare_2004_Org.Biomol.Chem_2_2942
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Title : 2-hydroxy-6-keto-nona-2,4-diene 1,9-dioic acid 5,6-hydrolase: evidence from 18O isotope exchange for gem-diol intermediate -
Author(s) : Bugg TD , Fleming SM , Robertson TA , Langley GJ
Ref : Methods Enzymol , 354 :106 , 2002
PubMedID: 12418219

Title : Hammett analysis of a C-C hydrolase-catalysed reaction using synthetic 6-aryl-2-hydroxy-6-ketohexa-2,4-dienoic acid substrates - Speare_2002_Chem.Commun.(Camb)__2304
Author(s) : Speare DM , Olf P , Bugg TD
Ref : Chem Commun (Camb) , :2304 , 2002
Abstract :
PubMedSearch : Speare_2002_Chem.Commun.(Camb)__2304
PubMedID: 12430413

Title : Oxygenases: mechanisms and structural motifs for O(2) activation - Bugg_2001_Curr.Opin.Chem.Biol_5_550
Author(s) : Bugg TD
Ref : Curr Opin Chemical Biology , 5 :550 , 2001
Abstract :
PubMedSearch : Bugg_2001_Curr.Opin.Chem.Biol_5_550
PubMedID: 11578928

Title : Catalytic mechanism of a C-C hydrolase enzyme: evidence for a gem-diol intermediate, not an acyl enzyme - Fleming_2000_Biochemistry_39_1522
Author(s) : Fleming SM , Robertson TA , Langley GJ , Bugg TD
Ref : Biochemistry , 39 :1522 , 2000
Abstract :
PubMedSearch : Fleming_2000_Biochemistry_39_1522
PubMedID: 10684634
Gene_locus related to this paper: ecoli-mhpc

Title : Pre-steady-state kinetic analysis of 2-hydroxy-6-keto-nona-2,4-diene-1,9-dioic acid 5,6-hydrolase: kinetic evidence for enol\/keto tautomerization - Henderson_1997_Biochemistry_36_12252
Author(s) : Henderson IM , Bugg TD
Ref : Biochemistry , 36 :12252 , 1997
Abstract :
PubMedSearch : Henderson_1997_Biochemistry_36_12252
PubMedID: 9315863
Gene_locus related to this paper: ecoli-mhpc

Title : Purification, characterization, and stereochemical analysis of a C-C hydrolase: 2-hydroxy-6-keto-nona-2,4-diene-1,9-dioic acid 5,6-hydrolase - Lam_1997_Biochemistry_36_12242
Author(s) : Lam WW , Bugg TD
Ref : Biochemistry , 36 :12242 , 1997
Abstract :
PubMedSearch : Lam_1997_Biochemistry_36_12242
PubMedID: 9315862
Gene_locus related to this paper: ecoli-mhpc