| Title : Multi-target Triazole-Benzopyrone hybrids modulating cholinergic dysfunction, oxidative stress, and neuroinflammation through GFAP\/NF-B\/APOE\/NLRP3 axis in Alzheimer's disease - El-Mokaddem_2026_Eur.J.Med.Chem_315_118949 |
| Author(s) : El-Mokaddem OK , Elmasry GF , Salama A , Mansour HM , Mahmoud WR , Ghany L |
| Ref : Eur Journal of Medicinal Chemistry , 315 :118949 , 2026 |
| Abstract : |
| PubMedSearch : El-Mokaddem_2026_Eur.J.Med.Chem_315_118949 |
| PubMedID: 42150247 |
| Title : Bridging the gap in Alzheimer's therapy: strategic design and SAR evolution of coumarin-based hybrids as potent MTDLs - El-Mokaddem_2026_RSC.Adv_16_29631 |
| Author(s) : El-Mokaddem OK , Elmasry GF , Mahmoud WR , Abdel Ghany LMA |
| Ref : RSC Adv , 16 :29631 , 2026 |
| Abstract : |
| PubMedSearch : El-Mokaddem_2026_RSC.Adv_16_29631 |
| PubMedID: 42239568 |
| Title : Rational design, synthesis and computational studies of multi-targeted anti-Alzheimer's agents integrating coumarin scaffold - Abd El-Mageed_2024_Bioorg.Chem_154_108024 |
| Author(s) : Abd El-Mageed MMA , Fattah Ezzat MA , Moussa SA , Abdel-Aziz HA , Elmasry GF |
| Ref : Bioorg Chem , 154 :108024 , 2024 |
| Abstract : |
| PubMedSearch : Abd El-Mageed_2024_Bioorg.Chem_154_108024 |
| PubMedID: 39642754 |
| Title : Combinative effects of akarkara root-derived metabolites on anti-inflammatory and anti-alzheimer key enzymes: integrating bioassay-guided fractionation, GC-MS analysis, and in silico studies - Ibrahim_2023_BMC.Complement.Med.Ther_23_413 |
| Author(s) : Ibrahim RM , Abdel-Baki PM , Elmasry GF , El-Rashedy AA , Mahdy NE |
| Ref : BMC Complement Med Ther , 23 :413 , 2023 |
| Abstract : |
| PubMedSearch : Ibrahim_2023_BMC.Complement.Med.Ther_23_413 |
| PubMedID: 37978514 |