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Grosman C

General

Full name : Grosman Claudio

First name : Claudio

Mail : Department of Molecular and Integrative Physiology, Center for Biophysics and Computational Biology, and Neuroscience Program, University of Illinois at Urbana-Champaign, Urbana, IL 61801

Zip Code :

City :

Country : USA

Email : grosman@illinois.edu

Phone : 1-217-244-1736

Fax : 1-217-333-1133

Website :

Directory :

Comment

References (22)

Title : Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals - Gonzalez-Gutierrez_2012_Proc.Natl.Acad.Sci.U.S.A_109_6331
Author(s) : Gonzalez-Gutierrez G , Lukk T , Agarwal V , Papke D , Nair SK , Grosman C
Ref : Proc Natl Acad Sci U S A , 109 :6331 , 2012
Abstract :
PubMedSearch : Gonzalez-Gutierrez_2012_Proc.Natl.Acad.Sci.U.S.A_109_6331
PubMedID: 22474383

Title : The unanticipated complexity of the selectivity-filter glutamates of nicotinic receptors - Cymes_2012_Nat.Chem.Biol_8_975
Author(s) : Cymes GD , Grosman C
Ref : Nat Chemical Biology , 8 :975 , 2012
Abstract :
PubMedSearch : Cymes_2012_Nat.Chem.Biol_8_975
PubMedID: 23064317

Title : Desensitization of neurotransmitter-gated ion channels during high-frequency stimulation: a comparative study of Cys-loop, AMPA and purinergic receptors - Papke_2011_J.Physiol_589_1571
Author(s) : Papke D , Gonzalez-Gutierrez G , Grosman C
Ref : The Journal of Physiology , 589 :1571 , 2011
Abstract :
PubMedSearch : Papke_2011_J.Physiol_589_1571
PubMedID: 21300749

Title : Estimating the pKa values of basic and acidic side chains in ion channels using electrophysiological recordings: a robust approach to an elusive problem - Cymes_2011_Proteins_79_3485
Author(s) : Cymes GD , Grosman C
Ref : Proteins , 79 :3485 , 2011
Abstract :
PubMedSearch : Cymes_2011_Proteins_79_3485
PubMedID: 21744391

Title : Tunable pKa values and the basis of opposite charge selectivities in nicotinic-type receptors - Cymes_2011_Nature_474_526
Author(s) : Cymes GD , Grosman C
Ref : Nature , 474 :526 , 2011
Abstract :
PubMedSearch : Cymes_2011_Nature_474_526
PubMedID: 21602825

Title : Bridging the gap between structural models of nicotinic receptor superfamily ion channels and their corresponding functional states - Gonzalez-Gutierrez_2010_J.Mol.Biol_403_693
Author(s) : Gonzalez-Gutierrez G , Grosman C
Ref : Journal of Molecular Biology , 403 :693 , 2010
Abstract :
PubMedSearch : Gonzalez-Gutierrez_2010_J.Mol.Biol_403_693
PubMedID: 20863833

Title : Decremental response to high-frequency trains of acetylcholine pulses but unaltered fractional Ca2+ currents in a panel of slow-channel syndrome nicotinic receptor mutants - Elenes_2009_J.Gen.Physiol_133_151
Author(s) : Elenes S , Decker M , Cymes GD , Grosman C
Ref : Journal of General Physiology , 133 :151 , 2009
Abstract :
PubMedSearch : Elenes_2009_J.Gen.Physiol_133_151
PubMedID: 19171769

Title : Pore-opening mechanism of the nicotinic acetylcholine receptor evinced by proton transfer - Cymes_2008_Nat.Struct.Mol.Biol_15_389
Author(s) : Cymes GD , Grosman C
Ref : Nat Struct Mol Biol , 15 :389 , 2008
Abstract :
PubMedSearch : Cymes_2008_Nat.Struct.Mol.Biol_15_389
PubMedID: 18376414

Title : Block of muscle nicotinic receptors by choline suggests that the activation and desensitization gates act as distinct molecular entities - Purohit_2006_J.Gen.Physiol_127_703
Author(s) : Purohit Y , Grosman C
Ref : Journal of General Physiology , 127 :703 , 2006
Abstract :
PubMedSearch : Purohit_2006_J.Gen.Physiol_127_703
PubMedID: 16735755

Title : Estimating binding affinities of the nicotinic receptor for low-efficacy ligands using mixtures of agonists and two-dimensional concentration-response relationships - Purohit_2006_J.Gen.Physiol_127_719
Author(s) : Purohit Y , Grosman C
Ref : Journal of General Physiology , 127 :719 , 2006
Abstract :
PubMedSearch : Purohit_2006_J.Gen.Physiol_127_719
PubMedID: 16735756

Title : Desensitization contributes to the synaptic response of gain-of-function mutants of the muscle nicotinic receptor - Elenes_2006_J.Gen.Physiol_128_615
Author(s) : Elenes S , Ni Y , Cymes GD , Grosman C
Ref : Journal of General Physiology , 128 :615 , 2006
Abstract :
PubMedSearch : Elenes_2006_J.Gen.Physiol_128_615
PubMedID: 17074980

Title : Probing ion-channel pores one proton at a time - Cymes_2005_Nature_438_975
Author(s) : Cymes GD , Ni Y , Grosman C
Ref : Nature , 438 :975 , 2005
Abstract :
PubMedSearch : Cymes_2005_Nature_438_975
PubMedID: 16355215

Title : Free-energy landscapes of ion-channel gating are malleable: changes in the number of bound ligands are accompanied by changes in the location of the transition state in acetylcholine-receptor channels - Grosman_2003_Biochemistry_42_14977
Author(s) : Grosman C
Ref : Biochemistry , 42 :14977 , 2003
Abstract :
PubMedSearch : Grosman_2003_Biochemistry_42_14977
PubMedID: 14674774

Title : Linear free-energy relationships and the dynamics of gating in the acetylcholine receptor channel - Grosman_2002_J.Biol.Phys_28_267
Author(s) : Grosman C
Ref : J Biol Phys , 28 :267 , 2002
Abstract :
PubMedSearch : Grosman_2002_J.Biol.Phys_28_267
PubMedID: 23345774

Title : Structure of the transition state of gating in the acetylcholine receptor channel pore: a phi-value analysis - Cymes_2002_Biochemistry_41_5548
Author(s) : Cymes GD , Grosman C , Auerbach A
Ref : Biochemistry , 41 :5548 , 2002
Abstract :
PubMedSearch : Cymes_2002_Biochemistry_41_5548
PubMedID: 11969415

Title : The dissociation of acetylcholine from open nicotinic receptor channels - Grosman_2001_Proc.Natl.Acad.Sci.U.S.A_98_14102
Author(s) : Grosman C , Auerbach A
Ref : Proc Natl Acad Sci U S A , 98 :14102 , 2001
Abstract :
PubMedSearch : Grosman_2001_Proc.Natl.Acad.Sci.U.S.A_98_14102
PubMedID: 11717464

Title : Depolarization of the tegument precedes morphological alterations in Echinococcus granulosus protoscoleces incubated with ivermectin - Perez-Serrano_2001_Parasitol.Res_87_804
Author(s) : Perez-Serrano J , Grosman C , Urrea-Paris MA , Denegri G , Casado N , Rodriguez-Caabeiro F
Ref : Parasitol Res , 87 :804 , 2001
Abstract :
PubMedSearch : Perez-Serrano_2001_Parasitol.Res_87_804
PubMedID: 11688885

Title : Asymmetric and independent contribution of the second transmembrane segment 12' residues to diliganded gating of acetylcholine receptor channels: a single-channel study with choline as the agonist - Grosman_2000_J.Gen.Physiol_115_637
Author(s) : Grosman C , Auerbach A
Ref : Journal of General Physiology , 115 :637 , 2000
Abstract :
PubMedSearch : Grosman_2000_J.Gen.Physiol_115_637
PubMedID: 10779320

Title : Kinetic, mechanistic, and structural aspects of unliganded gating of acetylcholine receptor channels: a single-channel study of second transmembrane segment 12' mutants - Grosman_2000_J.Gen.Physiol_115_621
Author(s) : Grosman C , Auerbach A
Ref : Journal of General Physiology , 115 :621 , 2000
Abstract :
PubMedSearch : Grosman_2000_J.Gen.Physiol_115_621
PubMedID: 10779319

Title : Single-channel characterization of a nonselective cation channel from human placental microvillus membranes. Large conductance, multiplicity of conductance states, and inhibition by lanthanides - Grosman_2000_J.Membr.Biol_174_59
Author(s) : Grosman C , Reisin IL
Ref : J Membr Biol , 174 :59 , 2000
Abstract :
PubMedSearch : Grosman_2000_J.Membr.Biol_174_59
PubMedID: 10741433

Title : Mapping the conformational wave of acetylcholine receptor channel gating - Grosman_2000_Nature_403_773
Author(s) : Grosman C , Zhou M , Auerbach A
Ref : Nature , 403 :773 , 2000
Abstract :
PubMedSearch : Grosman_2000_Nature_403_773
PubMedID: 10693806

Title : The extracellular linker of muscle acetylcholine receptor channels is a gating control element - Grosman_2000_J.Gen.Physiol_116_327
Author(s) : Grosman C , Salamone FN , Sine SM , Auerbach A
Ref : Journal of General Physiology , 116 :327 , 2000
Abstract :
PubMedSearch : Grosman_2000_J.Gen.Physiol_116_327
PubMedID: 10962011