| Title : Effects of steric hindrance and electron density of ester prodrugs on controlling the metabolic activation by human carboxylesterase - Takahashi_2021_Drug.Metab.Pharmacokinet_38_100391 |
| Author(s) : Takahashi M , Hirota I , Nakano T , Kotani T , Takani D , Shiratori K , Choi Y , Haba M , Hosokawa M |
| Ref : Drug Metab Pharmacokinet , 38 :100391 , 2021 |
| Abstract : |
| PubMedSearch : Takahashi_2021_Drug.Metab.Pharmacokinet_38_100391 |
| PubMedID: 33872946 |
| Title : Design, synthesis and biological evaluation of water-soluble phenytoin prodrugs considering the substrate recognition ability of human carboxylesterase 1 - Takahashi_2020_Eur.J.Pharm.Sci__105455 |
| Author(s) : Takahashi M , Lee YJ , Kanayama T , Kondo Y , Nishio K , Mukai K , Haba M , Hosokawa M |
| Ref : Eur J Pharm Sci , :105455 , 2020 |
| Abstract : |
| PubMedSearch : Takahashi_2020_Eur.J.Pharm.Sci__105455 |
| PubMedID: 32629019 |
| Title : Investigation of the chiral recognition ability of human carboxylesterase 1 using indomethacin esters - Takahashi_2020_Chirality_32_73 |
| Author(s) : Takahashi M , Takani D , Haba M , Hosokawa M |
| Ref : Chirality , 32 :73 , 2020 |
| Abstract : |
| PubMedSearch : Takahashi_2020_Chirality_32_73 |
| PubMedID: 31693270 |
| Title : Synthesis and evaluation of haloperidol ester prodrugs metabolically activated by human carboxylesterase - Takahashi_2019_Eur.J.Pharm.Sci_132_125 |
| Author(s) : Takahashi M , Uehara T , Nonaka M , Minagawa Y , Yamazaki R , Haba M , Hosokawa M |
| Ref : Eur J Pharm Sci , 132 :125 , 2019 |
| Abstract : |
| PubMedSearch : Takahashi_2019_Eur.J.Pharm.Sci_132_125 |
| PubMedID: 30878380 |
| Title : Structure-activity relationship of atorvastatin derivatives for metabolic activation by hydrolases - Mizoi_2019_Xenobiotica__1 |
| Author(s) : Mizoi K , Takahashi M , Sakai S , Ogihara T , Haba M , Hosokawa M |
| Ref : Xenobiotica , :1 , 2019 |
| Abstract : |
| PubMedSearch : Mizoi_2019_Xenobiotica__1 |
| PubMedID: 31173561 |
| Title : Chemical synthesis of an indomethacin ester prodrug and its metabolic activation by human carboxylesterase 1 - Takahashi_2018_Bioorg.Med.Chem.Lett_28_997 |
| Author(s) : Takahashi M , Ogawa T , Kashiwagi H , Fukushima F , Yoshitsugu M , Haba M , Hosokawa M |
| Ref : Bioorganic & Medicinal Chemistry Lett , 28 :997 , 2018 |
| Abstract : |
| PubMedSearch : Takahashi_2018_Bioorg.Med.Chem.Lett_28_997 |
| PubMedID: 29503023 |
| Title : Synthesis and evaluation of atorvastatin esters as prodrugs metabolically activated by human carboxylesterases - Mizoi_2016_Bioorg.Med.Chem.Lett_26_921 |
| Author(s) : Mizoi K , Takahashi M , Haba M , Hosokawa M |
| Ref : Bioorganic & Medicinal Chemistry Lett , 26 :921 , 2016 |
| Abstract : |
| PubMedSearch : Mizoi_2016_Bioorg.Med.Chem.Lett_26_921 |
| PubMedID: 26750256 |
| Title : Cholinesterase inhibitor donepezil dilates cerebral parenchymal arterioles via the activation of neuronal nitric oxide synthase - Nakahata_2008_Anesthesiology_109_124 |
| Author(s) : Nakahata K , Kinoshita H , Hama-Tomioka K , Ishida Y , Matsuda N , Hatakeyama N , Haba M , Kondo T , Hatano Y |
| Ref : Anesthesiology , 109 :124 , 2008 |
| Abstract : |
| PubMedSearch : Nakahata_2008_Anesthesiology_109_124 |
| PubMedID: 18580182 |