Hilvert D

Title : Computational design of catalytic dyads and oxyanion holes for ester hydrolysis - Richter_2012_J.Am.Chem.Soc_134_16197

Author(s) : Richter F , Blomberg R , Khare SD , Kiss G , Kuzin AP , Smith AJ , Gallaher J , Pianowski Z , Helgeson RC , Grjasnow A , Xiao R , Seetharaman J , Su M , Vorobiev S , Lew S , Forouhar F , Kornhaber GJ , Hunt JF , Montelione GT , Tong L , Houk KN , Hilvert D , Baker D

Ref : Journal of the American Chemical Society , 134 :16197 , 2012

Abstract :

PubMedSearch : Richter_2012_J.Am.Chem.Soc_134_16197

PubMedID: 22871159

Title : Structural reorganization and preorganization in enzyme active sites: comparisons of experimental and theoretically ideal active site geometries in the multistep serine esterase reaction cycle - Smith_2008_J.Am.Chem.Soc_130_15361

Author(s) : Smith AJ , Muller R , Toscano MD , Kast P , Hellinga HW , Hilvert D , Houk KN

Ref : Journal of the American Chemical Society , 130 :15361 , 2008

Abstract :

PubMedSearch : Smith_2008_J.Am.Chem.Soc_130_15361

PubMedID: 18939839

Hilvert D

References (2)

1. Computational design of catalytic dyads and oxyanion holes for ester hydrolysis - Richter_2012_J.Am.Chem.Soc_134_16197

2. Structural reorganization and preorganization in enzyme active sites: comparisons of experimental and theoretically ideal active site geometries in the multistep serine esterase reaction cycle - Smith_2008_J.Am.Chem.Soc_130_15361