Karnovsky MJ

General

Full name : Karnovsky Morris J

First name : Morris J

Mail : Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue Goldenson Building, Room 420 Boston, MA 02115

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Country : USA

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Website : \/\/neuro.med.harvard.edu\/people\/faculty\/morris-karnovsky

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Comment
Karnovsky was born in Johannesburg, South Africa in 1926 and departed January 2018 at the age of 91. Graduating in 1950 with an M.B.B.Ch., he continued his clinical work in the township as he simultaneously advanced science at an incredible pace receiving his D.Sc. - working closely with classmate 2002 Nobel laureate Sydney Brenner. Of note they both interned in the Department of Anatomy at Witwatersrand directed by Raymond A. Dart, discoverer of Australopithecus africanus (the Taung Child). Later he sought further training in London at the Hammersmith and the Royal Cancer Hospitals. In 1955, he made his way to Harvard Medical School. For histochemists, one of his most widely appreciated contributions was the extension of the horseradish peroxidase (HRP) tracer method to both the light and electron microscopic level, by introducing diaminobenzidine (DAB) as an electron donor. For cholinergikers he is the inventor of the Karnovsky staining of cholinesterase activity Morris J Karnovsky

References (3)

Title : Clusters of intramembranous particles on cultured myotubes at sites that are highly sensitive to acetylcholine - Yee_1978_Proc.Natl.Acad.Sci.U.S.A_75_3004
Author(s) : Yee AG , Fischbach GD , Karnovsky MJ
Ref : Proc Natl Acad Sci U S A , 75 :3004 , 1978
Abstract :
PubMedSearch : Yee_1978_Proc.Natl.Acad.Sci.U.S.A_75_3004
PubMedID: 96446

Title : The localization of cholinesterase activity in rat cardiac muscle by electron microscopy -
Author(s) : Karnovsky MJ
Ref : Journal of Cell Biology , 23 :217 , 1964
PubMedID:

Title : A direct-coloring thiocholine method for cholinesterases -
Author(s) : Karnovsky MJ , Roots L
Ref : Journal of Histochemistry & Cytochemistry , 12 :219 , 1964
PubMedID: 14187330