Lapchak PA

General

Full name : Lapchak Paul A

First name : Paul A

Mail : Department of Neurology and Neurosurgery, Cedars-Sinai Medical Center, Advanced Health Sciences Pavilion, Rm 8305, 127 S. San Vicente Blvd, Los Angeles, CA, 90048

Zip Code :

City :

Country : USA

Email : paul.lapchak@cshs.org

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References (38)

Title : Therapeutic potentials for glial cell line-derived neurotrophic factor (GDNF) based upon pharmacological activities in the CNS - Lapchak_1996_Rev.Neurosci_7_165
Author(s) : Lapchak PA
Ref : Rev Neurosci , 7 :165 , 1996
Abstract :
PubMedSearch : Lapchak_1996_Rev.Neurosci_7_165
PubMedID: 8916290

Title : Effects of chronic nerve growth factor treatment on hippocampal [3H]cytisine\/nicotinic binding sites and presynaptic nicotinic receptor function following fimbrial transections - Lapchak_1994_Neurosci_60_293
Author(s) : Lapchak PA , Araujo DM , Hefti F
Ref : Neuroscience , 60 :293 , 1994
Abstract :
PubMedSearch : Lapchak_1994_Neurosci_60_293
PubMedID: 8072684

Title : Poster: Chronic NGF treatment alters hippocampal muscarinic receptor function in rats with fimbrial transections -
Author(s) : Araujo DM , Lapchak PA , Hefti F
Ref : Life Sciences , 52(5-6) :588 , 1993
PubMedID:

Title : Nerve growth factor pharmacology: application to the treatment of cholinergic neurodegeneration in Alzheimer's disease - Lapchak_1993_Exp.Neurol_124_16
Author(s) : Lapchak PA
Ref : Experimental Neurology , 124 :16 , 1993
Abstract :
PubMedSearch : Lapchak_1993_Exp.Neurol_124_16
PubMedID: 8282073

Title : Cholinergic regulation of hippocampal brain-derived neurotrophic factor mRNA expression: evidence from lesion and chronic cholinergic drug treatment studies - Lapchak_1993_Neurosci_52_575
Author(s) : Lapchak PA , Araujo DM , Hefti F
Ref : Neuroscience , 52 :575 , 1993
Abstract :
PubMedSearch : Lapchak_1993_Neurosci_52_575
PubMedID: 8450959

Title : Regulation of hippocampal muscarinic receptor function by chronic nerve growth factor treatment in adult rats with fimbrial transections - Lapchak_1993_Neurosci_53_379
Author(s) : Lapchak PA , Araujo DM , Hefti F
Ref : Neuroscience , 53 :379 , 1993
Abstract :
PubMedSearch : Lapchak_1993_Neurosci_53_379
PubMedID: 8388084

Title : Poster: Muscarinic receptor-mediated control of hippocampal brain-derived neurotrophic factor (BDNF) mRNA expression -
Author(s) : Lapchak PA , Araujo DM , Hefti F
Ref : Life Sciences , 52(5-6) :585 , 1993
PubMedID:

Title : Effects of chronic basic fibroblast growth factor administration to rats with partial fimbrial transections on presynaptic cholinergic parameters and muscarinic receptors in the hippocampus: comparison with nerve growth factor - Araujo_1993_J.Neurochem_61_899
Author(s) : Araujo DM , Lapchak PA , Hefti F
Ref : Journal of Neurochemistry , 61 :899 , 1993
Abstract :
PubMedSearch : Araujo_1993_J.Neurochem_61_899
PubMedID: 8360689

Title : Protective effects of nerve growth factor and brain-derived neurotrophic factor on basal forebrain cholinergic neurons in adult rats with partial fimbrial transections -
Author(s) : Hefti F , Knusel B , Lapchak PA
Ref : Prog Brain Res , 98 :257 , 1993
PubMedID: 8248515

Title : BDNF and NGF treatment in lesioned rats: effects on cholinergic function and weight gain - Lapchak_1992_Neuroreport_3_405
Author(s) : Lapchak PA , Hefti F
Ref : Neuroreport , 3 :405 , 1992
Abstract :
PubMedSearch : Lapchak_1992_Neuroreport_3_405
PubMedID: 1633277

Title : Pharmacological stimulation reveals recombinant human nerve growth factor-induced increases of in vivo hippocampal cholinergic function measured in rats with partial fimbrial transections - Lapchak_1992_Neurosci_50_847
Author(s) : Lapchak PA , Jenden DJ , Hefti F
Ref : Neuroscience , 50 :847 , 1992
Abstract :
PubMedSearch : Lapchak_1992_Neurosci_50_847
PubMedID: 1448201

Title : Distribution of neurotensin receptors in mammalian brain. What it is telling us about its interactions with other neurotransmitter systems -
Author(s) : Quirion R , Rowe WB , Lapchak PA , Araujo DM , Beaudet A
Ref : Annals of the New York Academy of Sciences , 668 :109 , 1992
PubMedID: 1361109

Title : Neurotensin regulation of endogenous acetylcholine release from rat striatal slices is independent of dopaminergic tone - Lapchak_1991_J.Neurochem_56_651
Author(s) : Lapchak PA , Araujo DM , Quirion R , Beaudet A
Ref : Journal of Neurochemistry , 56 :651 , 1991
Abstract :
PubMedSearch : Lapchak_1991_J.Neurochem_56_651
PubMedID: 1899109

Title : Effect of recombinant human nerve growth factor on presynaptic cholinergic function in rat hippocampal slices following partial septohippocampal lesions: measures of [3H]acetylcholine synthesis, [3H]acetylcholine release and choline acetyltransferase activity - Lapchak_1991_Neurosci_42_639
Author(s) : Lapchak PA , Hefti F
Ref : Neuroscience , 42 :639 , 1991
Abstract :
PubMedSearch : Lapchak_1991_Neurosci_42_639
PubMedID: 1956513

Title : Emerging pharmacology of nerve growth factor - Lapchak_1991_Prog.Neuropsychopharmacol.Biol.Psychiatry_15_851
Author(s) : Lapchak PA , Hefti F
Ref : Prog Neuropsychopharmacol Biological Psychiatry , 15 :851 , 1991
Abstract :
PubMedSearch : Lapchak_1991_Prog.Neuropsychopharmacol.Biol.Psychiatry_15_851
PubMedID: 1763196

Title : Compensatory elevation of acetylcholine synthesis in vivo by cholinergic neurons surviving partial lesions of the septohippocampal pathway - Lapchak_1991_J.Neurosci_11_2821
Author(s) : Lapchak PA , Jenden DJ , Hefti F
Ref : Journal of Neuroscience , 11 :2821 , 1991
Abstract :
PubMedSearch : Lapchak_1991_J.Neurosci_11_2821
PubMedID: 1880551

Title : Growth factors and lymphokines: modulators of cholinergic neuronal activity - Quirion_1991_Can.J.Neurol.Sci_18_390
Author(s) : Quirion R , Araujo DM , Lapchak PA , Seto D , Chabot JG
Ref : Can Journal of Neurology Sci , 18 :390 , 1991
Abstract :
PubMedSearch : Quirion_1991_Can.J.Neurol.Sci_18_390
PubMedID: 1933687

Title : Heterogeneous binding of [3H]4-DAMP to muscarinic cholinergic sites in the rat brain: evidence from membrane binding and autoradiographic studies - Araujo_1991_Synapse_9_165
Author(s) : Araujo DM , Lapchak PA , Quirion R
Ref : Synapse , 9 :165 , 1991
Abstract :
PubMedSearch : Araujo_1991_Synapse_9_165
PubMedID: 1776129

Title : Opiate receptor-mediated inhibition of acetylcholine release from mammalian brain: tissue- and species-dependence -
Author(s) : Lapchak PA , Araujo DM , Collier B
Ref : Prog Clin Biol Res , 328 :347 , 1990
PubMedID: 2154791

Title : Chronic estradiol treatment alters central cholinergic function in the female rat: effect on choline acetyltransferase activity, acetylcholine content, and nicotinic autoreceptor function - Lapchak_1990_Brain.Res_525_249
Author(s) : Lapchak PA , Araujo DM , Quirion R , Beaudet A
Ref : Brain Research , 525 :249 , 1990
Abstract :
PubMedSearch : Lapchak_1990_Brain.Res_525_249
PubMedID: 2253030

Title : Neurotensin regulation of endogenous acetylcholine release from rat cerebral cortex: effect of quinolinic acid lesions of the basal forebrain - Lapchak_1990_J.Neurochem_55_1397
Author(s) : Lapchak PA , Araujo DM , Quirion R , Beaudet A
Ref : Journal of Neurochemistry , 55 :1397 , 1990
Abstract :
PubMedSearch : Lapchak_1990_J.Neurochem_55_1397
PubMedID: 2144584

Title : Cholinergic regulation of vasoactive intestinal peptide content and release in rat frontal cortex and hippocampus - Lapchak_1990_J.Neurochem_55_1340
Author(s) : Lapchak PA , Beaudet A
Ref : Journal of Neurochemistry , 55 :1340 , 1990
Abstract :
PubMedSearch : Lapchak_1990_J.Neurochem_55_1340
PubMedID: 2398362

Title : Evidence that somatostatin enhances endogenous acetylcholine release in the rat hippocampus - Araujo_1990_J.Neurochem_55_1546
Author(s) : Araujo DM , Lapchak PA , Collier B , Quirion R
Ref : Journal of Neurochemistry , 55 :1546 , 1990
Abstract :
PubMedSearch : Araujo_1990_J.Neurochem_55_1546
PubMedID: 1976754

Title : Interleukin-2 interacts with opioid neuroregulatory systems in the rat hippocampus -
Author(s) : Araujo DM , Lapchak PA , Collier B , Quirion R
Ref : Prog Clin Biol Res , 328 :355 , 1990
PubMedID: 2154793

Title : Effects of aging on nicotinic and muscarinic autoreceptor function in the rat brain: relationship to presynaptic cholinergic markers and binding sites - Araujo_1990_J.Neurosci_10_3069
Author(s) : Araujo DM , Lapchak PA , Meaney MJ , Collier B , Quirion R
Ref : Journal of Neuroscience , 10 :3069 , 1990
Abstract :
PubMedSearch : Araujo_1990_J.Neurosci_10_3069
PubMedID: 2398371

Title : Regulation of endogenous acetylcholine release from mammalian brain slices by opiate receptors: hippocampus, striatum and cerebral cortex of guinea-pig and rat - Lapchak_1989_Neurosci_31_313
Author(s) : Lapchak PA , Araujo DM , Collier B
Ref : Neuroscience , 31 :313 , 1989
Abstract :
PubMedSearch : Lapchak_1989_Neurosci_31_313
PubMedID: 2552347

Title : Binding sites for [3H]AF-DX 116 and effect of AF-DX 116 on endogenous acetylcholine release from rat brain slices - Lapchak_1989_Brain.Res_496_285
Author(s) : Lapchak PA , Araujo DM , Quirion R , Collier B
Ref : Brain Research , 496 :285 , 1989
Abstract :
PubMedSearch : Lapchak_1989_Brain.Res_496_285
PubMedID: 2804636

Title : Effect of chronic nicotine treatment on nicotinic autoreceptor function and N-[3H]methylcarbamylcholine binding sites in the rat brain - Lapchak_1989_J.Neurochem_52_483
Author(s) : Lapchak PA , Araujo DM , Quirion R , Collier B
Ref : Journal of Neurochemistry , 52 :483 , 1989
Abstract :
PubMedSearch : Lapchak_1989_J.Neurochem_52_483
PubMedID: 2911027

Title : Presynaptic cholinergic mechanisms in the rat cerebellum: evidence for nicotinic, but not muscarinic autoreceptors - Lapchak_1989_J.Neurochem_53_1843
Author(s) : Lapchak PA , Araujo DM , Quirion R , Collier B
Ref : Journal of Neurochemistry , 53 :1843 , 1989
Abstract :
PubMedSearch : Lapchak_1989_J.Neurochem_53_1843
PubMedID: 2809595

Title : Poster: Age-related changes in the muscarinic receplor autoregulation of acetylcholine release from rat brain -
Author(s) : Araujo DM , Lapchak PA , Collier B , Quirion R
Ref : Trends in Pharmacological Sciences , Suppl :104 , 1989
PubMedID:

Title : Insulin-like growth factor-1 (somatomedin-C) receptors in the rat brain: distribution and interaction with the hippocampal cholinergic system - Araujo_1989_Brain.Res_484_130
Author(s) : Araujo DM , Lapchak PA , Collier B , Chabot JG , Quirion R
Ref : Brain Research , 484 :130 , 1989
Abstract :
PubMedSearch : Araujo_1989_Brain.Res_484_130
PubMedID: 2540883

Title : Localization of interleukin-2 immunoreactivity and interleukin-2 receptors in the rat brain: interaction with the cholinergic system - Araujo_1989_Brain.Res_498_257
Author(s) : Araujo DM , Lapchak PA , Collier B , Quirion R
Ref : Brain Research , 498 :257 , 1989
Abstract :
PubMedSearch : Araujo_1989_Brain.Res_498_257
PubMedID: 2790482

Title : N-[3H]methylcarbamylcholine binding sites in the rat and human brain: relationship to functional nicotinic autoreceptors and alterations in Alzheimer's disease -
Author(s) : Araujo DM , Lapchak PA , Collier B , Quirion R
Ref : Prog Brain Res , 79 :345 , 1989
PubMedID: 2685905

Title : Muscarinic receptor subtypes in human neurodegenerative disorders: focus on Alzheimer's disease - Quirion_1989_Trends.Pharmacol.Sci_Suppl_80
Author(s) : Quirion R , Aubert I , Lapchak PA , Schaum RP , Teolis S , Gauthier S , Araujo DM
Ref : Trends in Pharmacological Sciences , Suppl :80 , 1989
Abstract :
PubMedSearch : Quirion_1989_Trends.Pharmacol.Sci_Suppl_80
PubMedID: 2694529

Title : Characterization of [3H]AF-DX 116 binding sites in the rat brain: evidence for heterogeneity of muscarinic-M2 receptor sites - Araujo_1989_Synapse_4_106
Author(s) : Araujo DM , Lapchak PA , Regenold W , Quirion R
Ref : Synapse , 4 :106 , 1989
Abstract :
PubMedSearch : Araujo_1989_Synapse_4_106
PubMedID: 2781463

Title : Vasoactive intestinal peptide increases acetylcholine synthesis by rat hippocampal slices - Lapchak_1988_J.Neurochem_50_58
Author(s) : Lapchak PA , Collier B
Ref : Journal of Neurochemistry , 50 :58 , 1988
Abstract :
PubMedSearch : Lapchak_1988_J.Neurochem_50_58
PubMedID: 2826690

Title : Characterization of N-[3H]methylcarbamylcholine binding sites and effect of N-methylcarbamylcholine on acetylcholine release in rat brain - Araujo_1988_J.Neurochem_51_292
Author(s) : Araujo DM , Lapchak PA , Collier B , Quirion R
Ref : Journal of Neurochemistry , 51 :292 , 1988
Abstract :
PubMedSearch : Araujo_1988_J.Neurochem_51_292
PubMedID: 3379410

Title : Differential alteration of various cholinergic markers in cortical and subcortical regions of human brain in Alzheimer's disease - Araujo_1988_J.Neurochem_50_1914
Author(s) : Araujo DM , Lapchak PA , Robitaille Y , Gauthier S , Quirion R
Ref : Journal of Neurochemistry , 50 :1914 , 1988
Abstract :
PubMedSearch : Araujo_1988_J.Neurochem_50_1914
PubMedID: 3373218