Full name : Raushel Frank M
First name : Frank M
Mail : Department of Chemistry, Texas AM University, College Station, TX 77843-3255
Zip Code :
City :
Country : USA
Email : raushel@tamu.edu
Phone : (1-409) 8453373
Fax : (1-409) 8459452
Website :
Directory :
Comment
Title : Substrate Analogues for the Enzyme-Catalyzed Detoxification of the Organophosphate Nerve Agents-Sarin, Soman, and Cyclosarin - Bigley_2021_Biochemistry__ |
Author(s) : Bigley AN , Harvey SP , Narindoshvili T , Raushel FM |
Ref : Biochemistry , : , 2021 |
Abstract : |
PubMedSearch : Bigley_2021_Biochemistry__ |
PubMedID: 34494832 |
Title : The evolution of phosphotriesterase for decontamination and detoxification of organophosphorus chemical warfare agents - Bigley_2019_Chem.Biol.Interact_13ChEPon_308_80 |
Author(s) : Bigley AN , Raushel FM |
Ref : Chemico-Biological Interactions , 308 :80 , 2019 |
Abstract : |
PubMedSearch : Bigley_2019_Chem.Biol.Interact_13ChEPon_308_80 |
PubMedID: 31100274 |
Title : Multiple Reaction Products from the Hydrolysis of Chiral and Prochiral Organophosphate Substrates by the Phosphotriesterase from Sphingobium sp. TCM1 - Bigley_2018_Biochemistry_57_1842 |
Author(s) : Bigley AN , Narindoshvili T , Xiang DF , Raushel FM |
Ref : Biochemistry , 57 :1842 , 2018 |
Abstract : |
PubMedSearch : Bigley_2018_Biochemistry_57_1842 |
PubMedID: 29513982 |
Title : An OPAA enzyme mutant with increased catalytic efficiency on the nerve agents sarin, soman, and GP - Bae_2018_Enzyme.Microb.Technol_112_65 |
Author(s) : Bae SY , Myslinski JM , McMahon LR , Height JJ , Bigley AN , Raushel FM , Harvey SP |
Ref : Enzyme Microb Technol , 112 :65 , 2018 |
Abstract : |
PubMedSearch : Bae_2018_Enzyme.Microb.Technol_112_65 |
PubMedID: 29499783 |
Title : Interrogation of the Substrate Profile and Catalytic Properties of the Phosphotriesterase from Sphingobium sp. Strain TCM1: An Enzyme Capable of Hydrolyzing Organophosphate Flame Retardants and Plasticizers - Xiang_2015_Biochemistry_54_7539 |
Author(s) : Xiang DF , Bigley AN , Ren Z , Xue H , Hull KG , Romo D , Raushel FM |
Ref : Biochemistry , 54 :7539 , 2015 |
Abstract : |
PubMedSearch : Xiang_2015_Biochemistry_54_7539 |
PubMedID: 26629649 |
Title : Catalytic mechanisms for phosphotriesterases - Bigley_2013_Biochim.Biophys.Acta_1834_443 |
Author(s) : Bigley AN , Raushel FM |
Ref : Biochimica & Biophysica Acta , 1834 :443 , 2013 |
Abstract : |
PubMedSearch : Bigley_2013_Biochim.Biophys.Acta_1834_443 |
PubMedID: 22561533 |
Title : Molecular engineering of organophosphate hydrolysis activity from a weak promiscuous lactonase template - Meier_2013_J.Am.Chem.Soc_135_11670 |
Author(s) : Meier MM , Rajendran C , Malisi C , Fox NG , Xu C , Schlee S , Barondeau DP , Hocker B , Sterner R , Raushel FM |
Ref : Journal of the American Chemical Society , 135 :11670 , 2013 |
Abstract : |
PubMedSearch : Meier_2013_J.Am.Chem.Soc_135_11670 |
PubMedID: 23837603 |
Title : Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents - Tsai_2012_Biochemistry_51_6463 |
Author(s) : Tsai PC , Fox N , Bigley AN , Harvey SP , Barondeau DP , Raushel FM |
Ref : Biochemistry , 51 :6463 , 2012 |
Abstract : |
PubMedSearch : Tsai_2012_Biochemistry_51_6463 |
PubMedID: 22809162 |
Title : Stereoselective hydrolysis of organophosphate nerve agents by the bacterial phosphotriesterase - Tsai_2010_Biochemistry_49_7978 |
Author(s) : Tsai PC , Bigley A , Li Y , Ghanem E , Cadieux CL , Kasten SA , Reeves TE , Cerasoli DM , Raushel FM |
Ref : Biochemistry , 49 :7978 , 2010 |
Abstract : |
PubMedSearch : Tsai_2010_Biochemistry_49_7978 |
PubMedID: 20701311 |
Title : Structure of diethyl phosphate bound to the binuclear metal center of phosphotriesterase - Kim_2008_Biochemistry_47_9497 |
Author(s) : Kim J , Tsai PC , Chen SL , Himo F , Almo SC , Raushel FM |
Ref : Biochemistry , 47 :9497 , 2008 |
Abstract : |
PubMedSearch : Kim_2008_Biochemistry_47_9497 |
PubMedID: 18702530 |
Title : Activation of the binuclear metal center through formation of phosphotriesterase-inhibitor complexes - Samples_2007_Biochemistry_46_3435 |
Author(s) : Samples CR , Raushel FM , DeRose VJ |
Ref : Biochemistry , 46 :3435 , 2007 |
Abstract : |
PubMedSearch : Samples_2007_Biochemistry_46_3435 |
PubMedID: 17315951 |
Title : Characterization of a phosphodiesterase capable of hydrolyzing EA 2192, the most toxic degradation product of the nerve agent VX - Ghanem_2007_Biochemistry_46_9032 |
Author(s) : Ghanem E , Li Y , Xu C , Raushel FM |
Ref : Biochemistry , 46 :9032 , 2007 |
Abstract : |
PubMedSearch : Ghanem_2007_Biochemistry_46_9032 |
PubMedID: 17630782 |
Title : Sensitivity and specificity improvement of an ion sensitive field effect transistors-based biosensor for potato glycoalkaloids detection - Korpan_2006_J.Agric.Food.Chem_54_707 |
Author(s) : Korpan YI , Raushel FM , Nazarenko EA , Soldatkin AP , Jaffrezic-Renault N , Martelet C |
Ref : Journal of Agricultural and Food Chemistry , 54 :707 , 2006 |
Abstract : |
PubMedSearch : Korpan_2006_J.Agric.Food.Chem_54_707 |
PubMedID: 16448172 |
Title : Detoxification of organophosphate nerve agents by bacterial phosphotriesterase - Ghanem_2005_Toxicol.Appl.Pharmacol_207_459 |
Author(s) : Ghanem E , Raushel FM |
Ref : Toxicol Appl Pharmacol , 207 :459 , 2005 |
Abstract : |
PubMedSearch : Ghanem_2005_Toxicol.Appl.Pharmacol_207_459 |
PubMedID: 15982683 |
Title : Access to the carbamate tunnel of carbamoyl phosphate synthetase - Kim_2004_Arch.Biochem.Biophys_425_33 |
Author(s) : Kim J , Raushel FM |
Ref : Archives of Biochemistry & Biophysics , 425 :33 , 2004 |
Abstract : |
PubMedSearch : Kim_2004_Arch.Biochem.Biophys_425_33 |
PubMedID: 15081891 |
Title : Enhanced degradation of chemical warfare agents through molecular engineering of the phosphotriesterase active site - Hill_2003_J.Am.Chem.Soc_125_8990 |
Author(s) : Hill CM , Li WS , Thoden JB , Holden HM , Raushel FM |
Ref : Journal of the American Chemical Society , 125 :8990 , 2003 |
Abstract : |
PubMedSearch : Hill_2003_J.Am.Chem.Soc_125_8990 |
PubMedID: 15369336 |
Title : High resolution X-ray structures of different metal-substituted forms of phosphotriesterase from Pseudomonas diminuta - Benning_2001_Biochemistry_40_2712 |
Author(s) : Benning MM , Shim H , Raushel FM , Holden HM |
Ref : Biochemistry , 40 :2712 , 2001 |
Abstract : |
PubMedSearch : Benning_2001_Biochemistry_40_2712 |
PubMedID: 11258882 |
Title : Stereochemical constraints on the substrate specificity of phosphotriesterase - Hong_1999_Biochemistry_38_1159 |
Author(s) : Hong SB , Raushel FM |
Ref : Biochemistry , 38 :1159 , 1999 |
Abstract : |
PubMedSearch : Hong_1999_Biochemistry_38_1159 |
PubMedID: 9930975 |
Title : Success of pyridostigmine, physostigmine, eptastigmine and phosphotriesterase treatments in acute sarin intoxication - Tuovinen_1999_Toxicology_134_169 |
Author(s) : Tuovinen K , Kaliste-Korhonen E , Raushel FM , Hanninen O |
Ref : Toxicology , 134 :169 , 1999 |
Abstract : |
PubMedSearch : Tuovinen_1999_Toxicology_134_169 |
PubMedID: 10403635 |
Title : Stereochemical preferences for chiral substrates by the bacterial phosphotriesterase - Hong_1999_Chem.Biol.Interact_119-120_225 |
Author(s) : Hong SB , Raushel FM |
Ref : Chemico-Biological Interactions , 119-120 :225 , 1999 |
Abstract : |
PubMedSearch : Hong_1999_Chem.Biol.Interact_119-120_225 |
PubMedID: 10421456 |
Title : Augmented hydrolysis of diisopropyl fluorophosphate in engineered mutants of phosphotriesterase - Watkins_1997_J.Biol.Chem_272_25596 |
Author(s) : Watkins LM , Mahoney HJ , McCulloch JK , Raushel FM |
Ref : Journal of Biological Chemistry , 272 :25596 , 1997 |
Abstract : |
PubMedSearch : Watkins_1997_J.Biol.Chem_272_25596 |
PubMedID: 9325279 |
Title : A combinatorial library for the binuclear metal center of bacterial phosphotriesterase - Watkins_1997_Proteins_29_553 |
Author(s) : Watkins LM , Kuo JM , Chen-Goodspeed M , Raushel FM |
Ref : Proteins , 29 :553 , 1997 |
Abstract : |
PubMedSearch : Watkins_1997_Proteins_29_553 |
PubMedID: 9408951 |
Title : Inhibitors directed towards the binuclear metal center of phosphotriesterase - Hong_1997_J.Enzyme.Inhib_12_191 |
Author(s) : Hong SB , Raushel FM |
Ref : J Enzyme Inhib , 12 :191 , 1997 |
Abstract : |
PubMedSearch : Hong_1997_J.Enzyme.Inhib_12_191 |
PubMedID: 9314115 |
Title : Three-dimensional structure of the zinc-containing phosphotriesterase with the bound substrate analog diethyl 4-methylbenzylphosphonate - Vanhooke_1996_Biochemistry_35_6020 |
Author(s) : Vanhooke JL , Benning MM , Raushel FM , Holden HM |
Ref : Biochemistry , 35 :6020 , 1996 |
Abstract : |
PubMedSearch : Vanhooke_1996_Biochemistry_35_6020 |
PubMedID: 8634243 |
Title : Eptastigmine-phosphotriesterase combination in DFP intoxication - Tuovinen_1996_Toxicol.Appl.Pharmacol_140_364 |
Author(s) : Tuovinen K , Kaliste-Korhonen E , Raushel FM , Hanninen O |
Ref : Toxicology & Applied Pharmacology , 140 :364 , 1996 |
Abstract : |
PubMedSearch : Tuovinen_1996_Toxicol.Appl.Pharmacol_140_364 |
PubMedID: 8887453 |
Title : Phosphotriesterase, pralidoxime-2-chloride (2-PAM) and eptastigmine treatments and their combinations in DFP intoxication - Tuovinen_1996_Toxicol.Appl.Pharmacol_141_555 |
Author(s) : Tuovinen K , Kaliste-Korhonen E , Raushel FM , Hanninen O |
Ref : Toxicology & Applied Pharmacology , 141 :555 , 1996 |
Abstract : |
PubMedSearch : Tuovinen_1996_Toxicol.Appl.Pharmacol_141_555 |
PubMedID: 8975781 |
Title : Three-dimensional structure of the binuclear metal center of phosphotriesterase - Benning_1995_Biochemistry_34_7973 |
Author(s) : Benning MM , Kuo JM , Raushel FM , Holden HM |
Ref : Biochemistry , 34 :7973 , 1995 |
Abstract : |
PubMedSearch : Benning_1995_Biochemistry_34_7973 |
PubMedID: 7794910 |
Title : Phosphotriesterase--a promising candidate for use in detoxification of organophosphates - Tuovinen_1994_Fundam.Appl.Toxicol_23_578 |
Author(s) : Tuovinen K , Kaliste-Korhonen E , Raushel FM , Hanninen O |
Ref : Fundamental & Applied Toxicology , 23 :578 , 1994 |
Abstract : |
PubMedSearch : Tuovinen_1994_Fundam.Appl.Toxicol_23_578 |
PubMedID: 7867909 |
Title : Phosphotriesterase decreases paraoxon toxicity in mice - Kaliste-Korhonen_1993_Toxicol.Appl.Pharmacol_121_275 |
Author(s) : Kaliste-Korhonen E , Ylitalo P , Hanninen O , Raushel FM |
Ref : Toxicol Appl Pharmacol , 121 :275 , 1993 |
Abstract : |
PubMedSearch : Kaliste-Korhonen_1993_Toxicol.Appl.Pharmacol_121_275 |
PubMedID: 8394035 |
Title : Limits of diffusion in the hydrolysis of substrates by the phosphotriesterase from Pseudomonas diminuta - Caldwell_1991_Biochemistry_30_7438 |
Author(s) : Caldwell SR , Newcomb JR , Schlecht KA , Raushel FM |
Ref : Biochemistry , 30 :7438 , 1991 |
Abstract : |
PubMedSearch : Caldwell_1991_Biochemistry_30_7438 |
PubMedID: 1649628 |
Title : Transition-state structures for enzymatic and alkaline phosphotriester hydrolysis - Caldwell_1991_Biochemistry_30_7444 |
Author(s) : Caldwell SR , Raushel FM , Weiss PM , Cleland WW |
Ref : Biochemistry , 30 :7444 , 1991 |
Abstract : |
PubMedSearch : Caldwell_1991_Biochemistry_30_7444 |
PubMedID: 1649629 |
Title : Purification and properties of the phosphotriesterase from Pseudomonas diminuta - Dumas_1989_J.Biol.Chem_264_19659 |
Author(s) : Dumas DP , Caldwell SR , Wild JR , Raushel FM |
Ref : Journal of Biological Chemistry , 264 :19659 , 1989 |
Abstract : |
PubMedSearch : Dumas_1989_J.Biol.Chem_264_19659 |
PubMedID: 2555328 |