Stedman E

General

Full name : Edgar Stedman

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Mail : Department of Medical Chemistry University of Edinburgh

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Country : United Kingdom

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Comment
Edgar Stedman was born in 1890 in Surrey and died on May 8,1975 in Virginia USA. At the university of Edinburgh, in 1922 he determined the structure of eseroline and physostigmine.and worked on the synthesis of Neostigmine-Prostigmine for treatment of glaucoma. Based on substrate specificity he recognized two types of cholinesterases in horse organs. With Leslie Easson he studied the inhibition by Miotine. Stedman studied the stereo-selectivity of the optical isomers of epinephrin and related molecules.

References (10)

Title : Central action of anticholinesterases -
Author(s) : Schweitzer A , Stedman E , Wright S
Ref : Journal of Physiology London , 96 :302 , 1939
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Title : Proc. Roy. Soc. 12IB: 142-164 -
Author(s) : Easson LR , Stedman E
Ref : Proc Roy Soc , 12IB :142 , 1936
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Title : The relative cholinesterase activities of serum and corpuscles from the blood of certain species -
Author(s) : Stedman E
Ref : Biochemical Journal , 29 :2107 , 1935
PubMedID: 16745885

Title : Studies on the relationship between chemical constitution and physiological action: Molecular dissymmetry and physiological activity. -
Author(s) : Easson LH , Stedman E
Ref : Biochemical Journal , 27 :1257 , 1933
PubMedID: 16745220

Title : Choline-esterase. An enzyme present in the blood-serum of the horse -
Author(s) : Stedman E , Easson LH
Ref : Biochemical Journal , 26 :2056 , 1932
PubMedID: 16745037

Title : Studies on the relationship between chemical constitution and physiological action: The inhibitory action of certain synthetic urethanes on the activity of liver esterase. -
Author(s) : Stedman E
Ref : Biochemical Journal , 25 :1147 , 1931
PubMedID: 16744678

Title : Chemical constitution and miotic action -
Author(s) : Stedman E
Ref : American Journal of Physiology , 90 :528 , 1929
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Title : Studies on the relationship between chemical constitution and physiological action: Part II. The miotic activity of urethanes derived from the isomeric hydroxybenzyldimethylamines. -
Author(s) : Stedman E
Ref : Biochemical Journal , 23 :17 , 1929
PubMedID: 16744184

Title : Studies on the relationship between chemical constitution and physiological action. 1. Position isomerism in relation to miotic activity of synthetic urethanes -
Author(s) : Stedman E
Ref : Biochemical Journal , 20 :719 , 1926
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Title : Physostigmine (eserine). Part III -
Author(s) : Stedman E , Banger G
Ref : J Chem Soc , 127 :247 , 1925
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