Tunek A

General

Full name : Tunek Anders

First name : Anders

Mail : Lead Generation DMPK & Physical Chemistry, Lead Generation Computational Chemistry, Discovery DMPK and Bioanalytical Chemistry, AstraZeneca R&D, Molndal, SE-431 88

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Country : Sweden

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References (12)

Title : Reversible fatty acid conjugation of budesonide. Novel mechanism for prolonged retention of topically applied steroid in airway tissue - Miller-Larsson_1998_Drug.Metab.Dispos_26_623
Author(s) : Miller-Larsson A , Mattsson H , Hjertberg E , Dahlback M , Tunek A , Brattsand R
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 26 :623 , 1998
Abstract :
PubMedSearch : Miller-Larsson_1998_Drug.Metab.Dispos_26_623
PubMedID: 9660844

Title : Synthesis and enzymatic hydrolysis of esters, constituting simple models of soft drugs - Graffner-Nordberg_1998_Chem.Pharm.Bull.(Tokyo)_46_591
Author(s) : Graffner-Nordberg M , Sjodin K , Tunek A , Hallberg A
Ref : Chem Pharm Bull (Tokyo) , 46 :591 , 1998
Abstract :
PubMedSearch : Graffner-Nordberg_1998_Chem.Pharm.Bull.(Tokyo)_46_591
PubMedID: 9579034

Title : Pharmacologic importance of the reversible fatty acid conjugation of budesonide studied in a rat cell line In vitro - Wieslander_1998_Am.J.Respir.Cell.Mol.Biol_19_477
Author(s) : Wieslander E , Delander EL , Jarkelid L , Hjertberg E , Tunek A , Brattsand R
Ref : American Journal of Respiratory Cellular & Molecular Biology , 19 :477 , 1998
Abstract :
PubMedSearch : Wieslander_1998_Am.J.Respir.Cell.Mol.Biol_19_477
PubMedID: 9730876

Title : Reversible formation of fatty acid esters of budesonide, an antiasthma glucocorticoid, in human lung and liver microsomes - Tunek_1997_Drug.Metab.Dispos_25_1311
Author(s) : Tunek A , Sjodin K , Hallstrom G
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 25 :1311 , 1997
Abstract :
PubMedSearch : Tunek_1997_Drug.Metab.Dispos_25_1311
PubMedID: 9351909

Title : Interactions of bambuterol with human serum cholinesterase of the genotypes EuEu (normal), EaEa (atypical) and EuEa - Tunek_1991_Biochem.Pharmacol_41_345
Author(s) : Tunek A , Hjertberg E , Mogensen JV
Ref : Biochemical Pharmacology , 41 :345 , 1991
Abstract :
PubMedSearch : Tunek_1991_Biochem.Pharmacol_41_345
PubMedID: 1994894

Title : Determination of bambuterol, a prodrug of terbutaline, in plasma and urine by gas chromatography\/mass spectrometry - Lindberg_1990_Biomed.Environ.Mass.Spectrom_19_218
Author(s) : Lindberg C , Jonsson S , Paulson J , Tunek A
Ref : Biomed Environ Mass Spectrom , 19 :218 , 1990
Abstract :
PubMedSearch : Lindberg_1990_Biomed.Environ.Mass.Spectrom_19_218
PubMedID: 2340359

Title : Metabolism of bambuterol in rat liver microsomes: identification of hydroxylated and demethylated products by liquid chromatography mass spectrometry - Lindberg_1989_Drug.Metab.Dispos_17_311
Author(s) : Lindberg C , Roos C , Tunek A , Svensson LA
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 17 :311 , 1989
Abstract :
PubMedSearch : Lindberg_1989_Drug.Metab.Dispos_17_311
PubMedID: 2568914

Title : Hydrolysis of 3H-bambuterol, a carbamate prodrug of terbutaline, in blood from humans and laboratory animals in vitro - Tunek_1988_Biochem.Pharmacol_37_3867
Author(s) : Tunek A , Levin E , Svensson LA
Ref : Biochemical Pharmacology , 37 :3867 , 1988
Abstract :
PubMedSearch : Tunek_1988_Biochem.Pharmacol_37_3867
PubMedID: 3190733

Title : Bambuterol, a carbamate ester prodrug of terbutaline, as inhibitor of cholinesterases in human blood - Tunek_1988_Drug.Metab.Dispos_16_759
Author(s) : Tunek A , Svensson LA
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 16 :759 , 1988
Abstract :
PubMedSearch : Tunek_1988_Drug.Metab.Dispos_16_759
PubMedID: 2906603

Title : Bambuterol: uptake and metabolism in guinea pig isolated lungs - Ryrfeldt_1988_Pharm.Res_5_151
Author(s) : Ryrfeldt A , Nilsson E , Tunek A , Svensson LA
Ref : Pharm Res , 5 :151 , 1988
Abstract :
PubMedSearch : Ryrfeldt_1988_Pharm.Res_5_151
PubMedID: 3244626

Title : The design and bioactivation of presystemically stable prodrugs -
Author(s) : Svensson LA , Tunek A
Ref : Drug Metabolism Reviews , 19 :165 , 1988
PubMedID: 3069421

Title : Poster 65. Bambuterol, a terbulaline carbamate prodrug, as substrate and inhibitor for cholinesterase in human blood -
Author(s) : Tunek A
Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter , 1984
PubMedID: