Title : A parallel-group, multicenter randomized, double-blinded, placebo-controlled, phase 2\/3, clinical trial to test the efficacy of pyridostigmine bromide at low doses to reduce mortality or invasive mechanical ventilation in adults with severe SARS-CoV-2 infection: the Pyridostigmine In Severe COvid-19 (PISCO) trial protocol - Fragoso-Saavedra_2020_BMC.Infect.Dis_20_765 |
Author(s) : Fragoso-Saavedra S , Iruegas-Nunez DA , Quintero-Villegas A , Garcia-Gonzalez HB , Nunez I , Carbajal-Morelos SL , Audelo-Cruz BM , Arias-Martinez S , Caro-Vega Y , Calva JJ , Luqueno-Martinez V , Gonzalez-Duarte A , Crabtree-Ramirez B , Crispin JC , Sierra-Madero J , Belaunzaran-Zamudio PF , Valdes-Ferrer SI |
Ref : BMC Infect Dis , 20 :765 , 2020 |
Abstract : |
PubMedSearch : Fragoso-Saavedra_2020_BMC.Infect.Dis_20_765 |
PubMedID: 33066761 |
Title : Forebrain Cholinergic Dysfunction and Systemic and Brain Inflammation in Murine Sepsis Survivors - Zaghloul_2017_Front.Immunol_8_1673 |
Author(s) : Zaghloul N , Addorisio ME , Silverman HA , Patel HL , Valdes-Ferrer SI , Ayasolla KR , Lehner KR , Olofsson PS , Nasim M , Metz CN , Wang P , Ahmed M , Chavan SS , Diamond B , Tracey KJ , Pavlov VA |
Ref : Front Immunol , 8 :1673 , 2017 |
Abstract : |
PubMedSearch : Zaghloul_2017_Front.Immunol_8_1673 |
PubMedID: 29326685 |
Title : alpha7 nicotinic acetylcholine receptor (alpha7nAChR) expression in bone marrow-derived non-T cells is required for the inflammatory reflex - Olofsson_2012_Mol.Med_18_539 |
Author(s) : Olofsson PS , Katz DA , Rosas-Ballina M , Levine YA , Ochani M , Valdes-Ferrer SI , Pavlov VA , Tracey KJ , Chavan SS |
Ref : Mol Med , 18 :539 , 2012 |
Abstract : |
PubMedSearch : Olofsson_2012_Mol.Med_18_539 |
PubMedID: 22183893 |
Title : Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit - Rosas-Ballina_2011_Science_334_98 |
Author(s) : Rosas-Ballina M , Olofsson PS , Ochani M , Valdes-Ferrer SI , Levine YA , Reardon C , Tusche MW , Pavlov VA , Andersson U , Chavan S , Mak TW , Tracey KJ |
Ref : Science , 334 :98 , 2011 |
Abstract : |
PubMedSearch : Rosas-Ballina_2011_Science_334_98 |
PubMedID: 21921156 |
Title : The selective alpha7 agonist GTS-21 attenuates cytokine production in human whole blood and human monocytes activated by ligands for TLR2, TLR3, TLR4, TLR9, and RAGE - Rosas-Ballina_2009_Mol.Med_15_195 |
Author(s) : Rosas-Ballina M , Goldstein RS , Gallowitsch-Puerta M , Yang L , Valdes-Ferrer SI , Patel NB , Chavan S , Al-Abed Y , Yang H , Tracey KJ |
Ref : Mol Med , 15 :195 , 2009 |
Abstract : |
PubMedSearch : Rosas-Ballina_2009_Mol.Med_15_195 |
PubMedID: 19593403 |
Title : Acetylcholine-esterase inhibitor pyridostigmine decreases T cell overactivation in patients infected by HIV - Valdes-Ferrer_2009_AIDS.Res.Hum.Retroviruses_25_749 |
Author(s) : Valdes-Ferrer SI , Crispin JC , Belaunzaran PF , Cantu-Brito CG , Sierra-Madero J , Alcocer-Varela J |
Ref : AIDS Res Hum Retroviruses , 25 :749 , 2009 |
Abstract : |
PubMedSearch : Valdes-Ferrer_2009_AIDS.Res.Hum.Retroviruses_25_749 |
PubMedID: 19645607 |