Title : Pharmacological activity and safety profile of P10358, a novel, orally active acetylcholinesterase inhibitor for Alzheimer's disease - Smith_1997_J.Pharmacol.Exp.Ther_280_710 |
Author(s) : Smith CP , Bores GM , Petko W , Li M , Selk DE , Rush DK , Camacho F , Winslow JT , Fishkin R , Cunningham DM , Brooks KM , Roehr J , Hartman HB , Davis L , Vargas HM |
Ref : Journal of Pharmacology & Experimental Therapeutics , 280 :710 , 1997 |
Abstract : |
PubMedSearch : Smith_1997_J.Pharmacol.Exp.Ther_280_710 |
PubMedID: 9023283 |
Title : Elevation of cerebrospinal fluid choline levels by nicotinamide involves the enzymatic formation of N1-methylnicotinamide in brain tissue - Vargas_1996_Life.Sci_58(22)_1995 |
Author(s) : Vargas HM , Jenden DJ |
Ref : Life Sciences , 58 :1995 , 1996 |
Abstract : |
PubMedSearch : Vargas_1996_Life.Sci_58(22)_1995 |
PubMedID: 8637429 |
Title : Pharmacological evaluation of novel Alzheimer's disease therapeutics: acetylcholinesterase inhibitors related to galanthamine - Bores_1996_J.Pharmacol.Exp.Ther_277_728 |
Author(s) : Bores GM , Huger FP , Petko W , Mutlib AE , Camacho F , Rush DK , Selk DE , Wolf V , Kosley RW, Jr. , Davis L , Vargas HM |
Ref : Journal of Pharmacology & Experimental Therapeutics , 277 :728 , 1996 |
Abstract : |
PubMedSearch : Bores_1996_J.Pharmacol.Exp.Ther_277_728 |
PubMedID: 8627552 |
Title : Alpha 2-adrenoceptor antagonists potentiate acetylcholinesterase inhibitor effects on passive avoidance learning in the rat - Camacho_1996_Psychopharmacology_124_347 |
Author(s) : Camacho F , Smith CP , Vargas HM , Winslow JT |
Ref : Psychopharmacology , 124 :347 , 1996 |
Abstract : |
PubMedSearch : Camacho_1996_Psychopharmacology_124_347 |
PubMedID: 8739550 |
Title : Effect of hemicholinium-3 on the hypothalamic concentration of a cytochemically detectable glucose-6-phosphate dehydrogenase-stimulating substance - Vargas_1994_J.Cardiovasc.Pharmacol_24_773 |
Author(s) : Vargas HM , Brezenoff HE , Morris HR , Panico M , Etienne A , Challand GS , Holland SM , Alaghband Zadeh J , de Wardener HE |
Ref : J Cardiovasc Pharmacol , 24 :773 , 1994 |
Abstract : |
PubMedSearch : Vargas_1994_J.Cardiovasc.Pharmacol_24_773 |
PubMedID: 7532755 |
Title : Phenyl-substituted analogues of oxotremorine as muscarinic antagonists - Nilsson_1992_J.Med.Chem_35_285 |
Author(s) : Nilsson BM , Vargas HM , Ringdahl B , Hacksell U |
Ref : Journal of Medicinal Chemistry , 35 :285 , 1992 |
Abstract : |
PubMedSearch : Nilsson_1992_J.Med.Chem_35_285 |
PubMedID: 1732545 |
Title : Resolved pyrrolidine, piperidine, and perhydroazepine analogues of the muscarinic agent N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide - Lundkvist_1990_J.Med.Chem_33_3182 |
Author(s) : Lundkvist JR , Vargas HM , Caldirola P , Ringdahl B , Hacksell U |
Ref : Journal of Medicinal Chemistry , 33 :3182 , 1990 |
Abstract : |
PubMedSearch : Lundkvist_1990_J.Med.Chem_33_3182 |
PubMedID: 2258904 |
Title : Centrally active antimuscarinic analogs of oxotremorine selectively block physostigmine-induced hypertension, but not peripheral muscarinic vasodepression - Vargas_1990_J.Pharmacol.Exp.Ther_253_165 |
Author(s) : Vargas HM , Ringdahl B |
Ref : Journal of Pharmacology & Experimental Therapeutics , 253 :165 , 1990 |
Abstract : |
PubMedSearch : Vargas_1990_J.Pharmacol.Exp.Ther_253_165 |
PubMedID: 2329503 |
Title : Antimuscarinic potency and functional selectivity of oxotremorine analogs at muscarinic receptor subtypes in the rat - Vargas_1990_Life.Sci_47_2065 |
Author(s) : Vargas HM , Ringdahl B |
Ref : Life Sciences , 47 :2065 , 1990 |
Abstract : |
PubMedSearch : Vargas_1990_Life.Sci_47_2065 |
PubMedID: 1703260 |
Title : Dimethylsulfonium analogues of the muscarinic agent McN-A-343: [4-[[N-(3- or 4-halophenyl)carbamoyl]oxy]-2-butynyl] dimethylsulfonium perchlorates - Mellin_1989_J.Med.Chem_32_1590 |
Author(s) : Mellin C , Vargas HM , Ringdahl B |
Ref : Journal of Medicinal Chemistry , 32 :1590 , 1989 |
Abstract : |
PubMedSearch : Mellin_1989_J.Med.Chem_32_1590 |
PubMedID: 2472484 |
Title : Suppression of hypertension during chronic reduction of brain acetylcholine in spontaneously hypertensive rats - Vargas_1988_J.Hypertens_6_739 |
Author(s) : Vargas HM , Brezenoff HE |
Ref : J Hypertens , 6 :739 , 1988 |
Abstract : |
PubMedSearch : Vargas_1988_J.Hypertens_6_739 |
PubMedID: 3183376 |