Hyperalphalipoproteinemia

Alternative name(s) : HALP

Gene_locus : 1

Mutation : 4

OMIM : No OMIM

Comment
extremely high HDL-cholesterol states of hyperalphalipoproteinemia (HALP). HALP1 is due tomutation in the cholesteryl ester transfer protein gene (CETP; 118470). But HALP may result from mutations in endothelial lipase (EL), a hydrolytic enzyme present in the circulation LIPG

References (2)

Title : Lipidome of high-density lipoprotein is strongly perturbed in hyperalphalipoproteinemia resulting from a rare mutation in endothelial lipase - Pisciotta_2025_Atheroscler.Plus_61_35
Author(s) : Pisciotta L , Lhomme M , Pavanello C , Ponnaiah M , Strazzella A , Ossoli A , Le Goff W , Calabresi L , Kontush A
Ref : Atheroscler Plus , 61 :35 , 2025
Abstract :
PubMedSearch : Pisciotta_2025_Atheroscler.Plus_61_35
PubMedID: 40703622
Gene_locus related to this paper: human-LIPG

Title : Plasma HDL pattern, cholesterol efflux and cholesterol loading capacity of serum in carriers of a novel missense variant (Gly176Trp) of endothelial lipase - Pisciotta_2022_J.Clin.Lipidol_S1933-2874_00235
Author(s) : Pisciotta L , Ossoli A , Ronca A , Garuti A , Fresa R , Favari E , Calabresi L , Calandra S , Bertolini S
Ref : J Clin Lipidol , : , 2022
Abstract :
PubMedSearch : Pisciotta_2022_J.Clin.Lipidol_S1933-2874_00235
PubMedID: 36002365
Gene_locus related to this paper: human-LIPG