Avian-virus_vlip
Relationship
Comment
This family has been recognized as alpha/beta hydrolase by Kamil et al. Previously associated with Lipoprotein_lipase family but is also close to phospholipase. vLIP may not serve as a traditional lipase enzyme, but the serine nucleophile position is essential in vivo for the viral functions of vLIP. Could be example of repurposing alpha/beta hydrolase fold toward a nonenzymatic role, possibly in lipid bonding
Database
Interpro : IPR000734 Lipase
PIRSF : No PIRSF
Pdoc : No Pdoc
Pfam : PF00151 Lipase , IPR013818 Lipase
Prints : No Print
EC Number : No EC Number
Sequences
| Peptide in | Fasta |
| Nucleotide in | Fasta |
| Alignment with Multalin | Text only |
| Seed alignment with MAFFT | No colour / coloured with Mview |
| Alignment with MAFFT | No colour / coloured with Mview |
| Dendrogram | The dnd file |
| Gene_locus | Name | Species |
|---|---|---|
| aviad-O55278 | Avian adenovirus, orf2 | Fowl adenovirus 10 |
| aviad-Q64767 | Avian adenovirus gal1 (strain Phelps) (Fowl adenovirus 1) (CELO) orf19 | Avian adenovirus gal1 |
| aviad-Q64777 | Avian adenovirus gal1 (strain Phelps) (Fowl adenovirus 1) (CELO) orf5 protein (fragment) | Avian adenovirus gal1 |
| aviad-Q9Q9I2 | Avian adenovirus type 8 (strain ATCC A-2A) (Fowl adenovirus 8) triacylglycerol lipase homolog | Avian adenovirus type 8 |
| aviad-RTL6 | Avian adenovirus type 8 (strain ATCC A-2A) (Fowl adenovirus 8) hypothetical protein | Avian adenovirus type 8 |
| mardi-ORF1 | Marek disease virus type 1\; allid herpesvirus 2, orf-1 protein. Viral lipase homolog | Marek disease virus type 1 |
| melhe-LORF1 | Meleagrid herpesvirus 1 (herpesvirus of turkeys) phospholipase-like protein | Meleagrid herpesvirus 1 |
References (1)
| Title : vLIP, a viral lipase homologue, is a virulence factor of Marek's disease virus - Kamil_2005_J.Virol_79_6984 |
| Author(s) : Kamil JP , Tischer BK , Trapp S , Nair VK , Osterrieder N , Kung HJ |
| Ref : J Virol , 79 :6984 , 2005 |
| Abstract : |
| PubMedSearch : Kamil_2005_J.Virol_79_6984 |
| PubMedID: 15890938 |
| Gene_locus related to this paper: mardi-ORF1 |