Lipase_bact_N_lipase

Relationship

Family: Lipase_bact_N_lipase

Block: X

Parent Family: No family

Comment

This family has the N-terminal region of bacterial virulence factor lipase. The N-terminal region contains a potential signalling sequence. Most proteins with this N-terminal sequence have a typical alpha/beta hydrolase following in c-term. The N-terminal region is found also in proteins without lipase or alpha/beta hydrolases. The N-term domain is used to populate the family but is excluded here. Chuang et al. on aerhy-LIP found hydrolysis of p-nitrophenyl esters (optimum C10-C12) and triacylglycerols (optimum C8- C10)

Database

Sequences

Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour / coloured with Mview
Alignment with MAFFT No colour / coloured with Mview
Dendrogram The dnd file

Gene_locus Name Species
9zzzz-a0a0g3fe15 uncultured organism EH75 Uncharacterized protein uncultured organism
aerhy-LIP Aeromonas hydrophila extracellular lipase Aeromonas hydrophila
aerhy-lipe Aeromonas hydrophila extracellular lipase (lip) [H3 Genomic 2842 nt] Aeromonas hydrophila
aerhy-PLA Aeromonas hydrophila phospholipase a1 Aeromonas hydrophila
aerhy-Q44055 Aeromonas hydrophila phospholipase c Aeromonas hydrophila
sheon-SO2934 Shewanella oneidensis conserved hypothetical protein Shewanella oneidensis
vibch-VCA0863 Vibrio cholerae lipase, putative Vibrio cholerae
vibpa-VPA0859 Vibrio parahaemolyticus putative lipase Vibrio parahaemolyticus
vibvu-VV20248 Vibrio vulnificus hydrolases of the alpha\/beta superfamily Vibrio vulnificus
9bact-estC55.102 uncultured bacterium. Lipolytic protein estC55-102 uncultured bacterium

Substrate Chemical Nomenclature Proteins
Paranitrophenyl-decanoate (4-nitrophenyl) decanoate
Paranitrophenyl-laurate (4-nitrophenyl) dodecanoate copci-b9u443    thite-g2rae6    crysp-Q874E9    9gamm-urc15994
Tributyrin 2,3-di(butanoyloxy)propyl butanoate bovin-balip    rabit-1cxes    pseae-llipa    canar-LipB    human-PNLIPRP2    talth-f6lqk7    nech7-c7yuz1    cavpo-2plrp    human-CEL    human-PNLIP    canan-lipasA    rhimi-lipas    rhidl-lipas    psesp-Q9RBY1    staha-Q9RGZ6    9bact-6EB3

References (4)

Title : Cloning, sequencing, and role in virulence of two phospholipases (A1 and C) from mesophilic Aeromonas sp. serogroup O:34 - Merino_1999_Infect.Immun_67_4008
Author(s) : Merino S , Aguilar A , Nogueras MM , Regue M , Swift S , Tomas JM
Ref : Infect Immun , 67 :4008 , 1999
Abstract :
PubMedSearch : Merino_1999_Infect.Immun_67_4008
PubMedID: 10417167
Gene_locus related to this paper: aerhy-PLA

Title : Molecular analysis and expression of the extracellular lipase of Aeromonas hydrophila MCC-2 - Chuang_1997_Microbiology_143 ( Pt 3)_803
Author(s) : Chuang YC , Chiou SF , Su JH , Wu ML , Chang MC
Ref : Microbiology , 143 ( Pt 3) :803 , 1997
Abstract :
PubMedSearch : Chuang_1997_Microbiology_143 ( Pt 3)_803
PubMedID: 9084164
Gene_locus related to this paper: aerhy-LIP

Title : Purification and characterization of a Chinese hamster ovary cell elongation factor of Vibrio hollisae - Kothary_1995_Infect.Immun_63_2418
Author(s) : Kothary MH , Claverie EF , Miliotis MD , Madden JM , Richardson SH
Ref : Infect Immun , 63 :2418 , 1995
Abstract :
PubMedSearch : Kothary_1995_Infect.Immun_63_2418
PubMedID: 7790052

Title : Purification, gene cloning, amino acid sequence analysis, and expression of an extracellular lipase from an Aeromonas hydrophila human isolate - Anguita_1993_Appl.Environ.Microbiol_59_2411
Author(s) : Anguita J , Rodriguez Aparicio LB , Naharro G
Ref : Applied Environmental Microbiology , 59 :2411 , 1993
Abstract :
PubMedSearch : Anguita_1993_Appl.Environ.Microbiol_59_2411
PubMedID: 8368830
Gene_locus related to this paper: aerhy-lipe