1. Home
  2. Gene Locus
  3. 9hyph-v5re33

9hyph-v5re33

Rhizobium favelukesii RgcR alpha/beta hydrolase

Comment

RcgA (Rhizobial Conjugative Gene A), from a Rhizobium favelukesii plasmid, plays an essential role in a quorum-sensing-dependent conjugative transfer system. It is thought to be a transporter that allows uptake of a quorum-signalling lactone. Its partner protein, RgcR, with an \/ hydrolase domain, inhibits the transfer, probably by inactivating the signalling molecule. 9hyph-v5re33 is the type of this family (Putative catalytic triad S194, D279, H310). The nucleophile residue of the catalytic triad can be Ser or Cys.

Relationship

Family : RcgR-like

Block : X

Position in NCBI Life Tree : Rhizobium favelukesii

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Bacteria N E > Proteobacteria N E > Alphaproteobacteria N E > Rhizobiales N E > Rhizobiaceae N E > Rhizobium\/Agrobacterium group N E > Rhizobium N E > Rhizobium favelukesii N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MYLSWLDRWD EQRARLGEDG KETTSFILDA DRAFPGEEIG SIREFLARAD EASTDPTFFD EQNGGDQRFD VREHWVKFPS DNSTDVAENN IVWAKITKSG SLDKALVIFH HWNARARNAQ IAGFLSRRGI TVVEIAMPYH FERSRPGSLH ADYMLSANLG RTIQAVRQAV CDGRKLIRWL KSQGYREISV LGMSLGSWVA GLIAAHDPNV SKASLFLTGG SLADMVWTGR ATRSIRRSLE SEIELADLRR AWGPLNLENS AHRLARPDLD LQVVLAKRDT VVMPELSESL LRSLKIAGGQ PQILKLNCGH YSLGKLPYIL YAGLSLKRFL S

References (2)

Title : RcgA and RcgR, Two Novel Proteins Involved in the Conjugative Transfer of Rhizobial Plasmids - Castellani_2022_mBio_13_e0194922
Author(s) : Castellani LG , Luchetti A , Nilsson JF , Perez-Gimenez J , Struck B , Schluter A , Puhler A , Niehaus K , Romero D , Pistorio M , Torres Tejerizo G
Ref : MBio , 13 :e0194922 , 2022
Abstract :
PubMedSearch : Castellani_2022_mBio_13_e0194922
PubMedID: 36073816
Gene_locus related to this paper: 9hyph-v5re33

Title : Rhizobial plasmid pLPU83a is able to switch between different transfer machineries depending on its genomic background - Torres Tejerizo_2014_FEMS.Microbiol.Ecol_88_565
Author(s) : Torres Tejerizo G , Pistorio M , Althabegoiti MJ , Cervantes L , Wibberg D , Schluter A , Puhler A , Lagares A , Romero D , Brom S
Ref : FEMS Microbiol Ecol , 88 :565 , 2014
Abstract :
PubMedSearch : Torres Tejerizo_2014_FEMS.Microbiol.Ecol_88_565
PubMedID: 24646299
Gene_locus related to this paper: 9hyph-v5re33