fratt-q5ni32

Francisella tularensis (subsp. tularensis)(and subsp. holarctica (strain LVS)) carboxylesterase/phospholipase family protein (EC 3.1.1.-)

Comment

Relationship

Family : LYsophospholipase_carboxylesterase

Block : X

Position in NCBI Life Tree : Francisella tularensis

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Bacteria N E > Proteobacteria N E > Gammaproteobacteria N E > Thiotrichales N E > Francisellaceae N E > Francisella N E > Francisella tularensis N E

Molecular evidence

No mutation

No kinetic

No disease

No substrate

Database

Sequence

Peptide

MNYELMEPAK QARFCVIWLH GLGADGHDFV DIVNYFDVSL DEIRFIFPHA DIIPVTINMG MQMRAWYDIK SLDANSLNRV VDVEGINSSI AKVNKLIDSQ VNQGIASENI ILAGFSQGGI IATYTAITSQ RKLGGIMALS TYLPAWDNFK GKITSINKGL PILVCHGTDD QVLPEVLGHD LSDKLKVSGF ANEYKHYVGM QHSVCMEEIK DISNFIAKTF KI

References (3)

Title : A dynamic loop provides dual control over the catalytic and membrane binding activity of a bacterial serine hydrolase - Smith_2018_Biochim.Biophys.Acta_1866_925
Author(s) : Smith MA , Phillips WK , Rabin PL , Johnson RJ
Ref : Biochimica & Biophysica Acta , 1866 :925 , 2018
PubMedID: 29857162
Gene_locus related to this paper: fratt-q5ni32

Title : Large-scale structural rearrangement of a serine hydrolase from Francisella tularensis facilitates catalysis - Filippova_2013_J.Biol.Chem_288_10522
Author(s) : Filippova EV , Weston LA , Kuhn ML , Geissler B , Gehring AM , Armoush N , Adkins CT , Minasov G , Dubrovska I , Shuvalova L , Winsor JR , Lavis LD , Satchell KJ , Becker DP , Anderson WF , Johnson RJ
Ref : Journal of Biological Chemistry , 288 :10522 , 2013
PubMedID: 23430251
Gene_locus related to this paper: fratt-q5ni32

Title : The complete genome sequence of Francisella tularensis, the causative agent of tularemia - Larsson_2005_Nat.Genet_37_153
Author(s) : Larsson P , Oyston PC , Chain P , Chu MC , Duffield M , Fuxelius HH , Garcia E , Halltorp G , Johansson D , Isherwood KE , Karp PD , Larsson E , Liu Y , Michell S , Prior J , Prior R , Malfatti S , Sjostedt A , Svensson K , Thompson N , Vergez L , Wagg JK , Wren BW , Lindler LE , Andersson SG , Forsman M , Titball RW
Ref : Nat Genet , 37 :153 , 2005
PubMedID: 15640799
Gene_locus related to this paper: fratt-q5ng35 , fratt-q5nga8 , fratt-q5ngu5 , fratt-q5ni32 , fratu-q7wvf7