melaz-MaCXE

Melia azedarach carboxylesterase Alpha/beta hydrolase fold-3 domain-containing protein

Comment

carboxylesterase that selectively deprotects a late-stage intermediate in synthesis of furamoids, so triggering more efficient furan biosynthesis

Relationship

Family : Plant_carboxylesterase

Block : H

Position in NCBI Life Tree : Melia azedarach

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

No Interpro

No Pfam

No UniProt

No PIRSF

No SUPERFAM

Sequence

Peptide

MIDHHPQKAN MSNETALSLS NIDPYQYLQI IPNPDGTLTR DYSLFPSTAA TPDPVDDIEV LSKDVTINQS SNLWVRIFLP RFQALEDSNS SSKKLPLIVY FHGGGFILFS SATSMTHDFC SDMANEFPAV IVSVEYRLAP ENRLPAAYDD AMEALQWIKT TEEEWLTKNA DISSCFLMGS SAGGNIAYNA GLRAAADVDN LLPLKIRGLI LHSPFFSGAK RTESELRLEY NMYLPACVID LMWKLSLPIG ADRDHEYCNP TVGGGSKLLE QMQLLGWKVM VTGCEGDPLI DRETELAKIM KEKGLKVVSH FVEGGFHTVE VIDTSKTKPF VTVLKNFLLS STMAPCEE

References (1)

Title : Plants Utilize a Protection\/Deprotection Strategy in Limonoid Biosynthesis: A Missing Link Carboxylesterase Boosts Yields and Provides Insights into Furan Formation - Hodgson_2024_J.Am.Chem.Soc__
Author(s) : Hodgson H , Stephenson MJ , Kikuchi S , Martin LBB , Liu JCT , Casson R , Rejzek M , Sattely ES , Osbourn A
Ref : Journal of the American Chemical Society , : , 2024
Abstract :
PubMedSearch : Hodgson_2024_J.Am.Chem.Soc__
PubMedID: 39418479
Gene_locus related to this paper: melaz-MaCXE , citcl-v4u7o7