Pseudomonas species (strain 109) gene for lactonizing lipase
efficiently catalyzes intramolecular transesterification of omega-hydroxyesters to form macrocyclic lactones. The production of the enzymatically active LipL requires a specific molecular chaperon (LimL protein) together with a low-M(r) lipase-activation-factor (LAF) (reduced form of glutathione) for formation of intermolecular disulfide bound
Family : Bacterial_lip_FamI.1
Block : L
Position in NCBI Life Tree : Pseudomonas sp.
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Bacteria N E > Proteobacteria N E > Gammaproteobacteria N E > Pseudomonadales N E > Pseudomonadaceae N E > Pseudomonas N E > Pseudomonas sp. N EMKKKSLLPLG LAIGLASLAA SPLIQASTYT QTKYPIVLAH GMLGFDNILG VDYWFGIPSA LRRDGAQVYV TEVSQLDTSE VRGEQLLQQV EEIVALSGQP KVNLIGHSHG GPTIRYVAAV RPDLMPSATS VGAPHKGSDT ADFLRQIPPG SAGEAVLSGL VNSLGALISF LSSGSAGTQN SLGSLESLNS EGAARFNAKY PQGIPTSACG EGAYKVNGVS YYSWSGSSPL TNFLDPSDAF LGASSLTFKN GTANDGLVGT CSSHLGMVIR DNYRMNHLDE VNQVFGLTSL FETSPVSVYR QHANRLKNAS L
| Title : Glutathione as an essential factor for chaperon-mediated activation of lactonizing lipase (LipL) from Pseudomonas sp. 109 - Tanaka_2000_J.Biochem_127_597 |
| Author(s) : Tanaka J , Nihira T , Yamada Y |
| Ref : J Biochem , 127 :597 , 2000 |
| Abstract : |
| PubMedSearch : Tanaka_2000_J.Biochem_127_597 |
| PubMedID: 10739951 |
| Gene_locus related to this paper: psesp-llipa |
| Title : Purification, characterization, and molecular cloning of lactonizing lipase from Pseudomonas species - Ihara_1991_J.Biol.Chem_266_18135 |
| Author(s) : Ihara F , Kageyama Y , Hirata M , Nihira T , Yamada Y |
| Ref : Journal of Biological Chemistry , 266 :18135 , 1991 |
| Abstract : |
| PubMedSearch : Ihara_1991_J.Biol.Chem_266_18135 |
| PubMedID: 1917947 |
| Gene_locus related to this paper: psesp-llipa |