Tabernanthe iboga (Iboga) ()-voacangine esterase Esterase 3, polyneudridine aldehyde esterase-like 3 (TiPNAE3)
Incubation of T. iboga polyneudridine aldehyde esterase-like 2 (TiPNAE2) with ()-voacangine yields a product with a mass consistent with the de-esterified compound 15, which then slowly converted to ()-ibogaine
MATQNSSSCR HFVLVHGANH GAWCWYKLKT LLEEAGHKVT AVDLAASGQN LVPLNDLQTM DDYHKPLYSY MAALAAEDRV ILVGHSYGGL AVSSAMERFP SKIALAVFVT AGMVGPNFTA NELWEKMSSV EGPDFFEDSV TTVYPNENMD LEAGPEFLKH KLYNLSPLED YTLARLLTRA TRIFCDNKSI LDHLVSKERY GTVPRAYFIV TDDKATSEEI QRVMIEATPP NEIREIRGAD HFVMLSKPLE LCHNLLEVAM KYY
| Title : Biosynthesis of an Anti-Addiction Agent from the Iboga Plant - Farrow_2019_J.Am.Chem.Soc_141_12979 |
| Author(s) : Farrow SC , Kamileen MO , Caputi L , Bussey K , Mundy JEA , McAtee RC , Stephenson CRJ , O'Connor SE |
| Ref : Journal of the American Chemical Society , 141 :12979 , 2019 |
| Abstract : Farrow_2019_J.Am.Chem.Soc_141_12979 |
| ESTHER : Farrow_2019_J.Am.Chem.Soc_141_12979 |
| PubMedSearch : Farrow_2019_J.Am.Chem.Soc_141_12979 |
| PubMedID: 31364847 |
| Gene_locus related to this paper: tabib-TiPNAE1 , tabib-TiPNAE2 , tabib-TiPNAE3 , tabib-a0a5b8x6s2 , tabib-CorS |