Tabernanthe iboga (Iboga) ()-voacangine esterase Esterase 3, polyneudridine aldehyde esterase-like 3 (TiPNAE3)
Incubation of T. iboga polyneudridine aldehyde esterase-like 2 (TiPNAE2) with ()-voacangine yields a product with a mass consistent with the de-esterified compound 15, which then slowly converted to ()-ibogaine
Family : Hydroxynitrile_lyase
Block : X
Position in NCBI Life Tree : Tabernanthe iboga
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Eukaryota N E > Viridiplantae N E > Streptophyta N E > Streptophytina N E > Embryophyta N E > Tracheophyta N E > Euphyllophyta N E > Spermatophyta N E > Magnoliophyta N E > Mesangiospermae N E > eudicotyledons N E > Gunneridae N E > Pentapetalae N E > asterids N E > lamiids N E > Gentianales N E > Apocynaceae N E > Rauvolfioideae N E > Tabernaemontaneae N E > Tabernaemontaninae N E > Tabernanthe N E > Tabernanthe iboga N EMATQNSSSCR HFVLVHGANH GAWCWYKLKT LLEEAGHKVT AVDLAASGQN LVPLNDLQTM DDYHKPLYSY MAALAAEDRV ILVGHSYGGL AVSSAMERFP SKIALAVFVT AGMVGPNFTA NELWEKMSSV EGPDFFEDSV TTVYPNENMD LEAGPEFLKH KLYNLSPLED YTLARLLTRA TRIFCDNKSI LDHLVSKERY GTVPRAYFIV TDDKATSEEI QRVMIEATPP NEIREIRGAD HFVMLSKPLE LCHNLLEVAM KYY
Title : Biosynthesis of an Anti-Addiction Agent from the Iboga Plant - Farrow_2019_J.Am.Chem.Soc_141_12979 |
Author(s) : Farrow SC , Kamileen MO , Caputi L , Bussey K , Mundy JEA , McAtee RC , Stephenson CRJ , O'Connor SE |
Ref : Journal of the American Chemical Society , 141 :12979 , 2019 |
Abstract : |
PubMedSearch : Farrow_2019_J.Am.Chem.Soc_141_12979 |
PubMedID: 31364847 |
Gene_locus related to this paper: tabib-TiPNAE1 , tabib-TiPNAE2 , tabib-TiPNAE3 , tabib-a0a5b8x6s2 , tabib-CorS |