Alizarin
It has a role as a chromophore, a dye and a plant metabolite. It has been used throughout history as a red dye, principally for dyeing textile fabrics. Historically it was derived from the roots of plants of the madder genus.[3] In 1869, it became the first natural dye to be produced synthetically. Rubia tinctorum (garance des teinturiers), the rose madder or common madder or dyer's madder, is a herbaceous perennial plant species belonging to the bedstraw and coffee family Rubiaceae IC50 hPL 0.33 +/- 0.05 microM mixed inhibition
General
Chemical_Nomenclature : 1,2-dihydroxyanthracene-9,10-dione
Canonical SMILES : C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C(=C(C=C3)O)O
InChI : InChI=1S\/C14H8O4\/c15-10-6-5-9-11(14(10)18)13(17)8-4-2-1-3-7(8)12(9)16\/h1-6,15,18H
InChIKey : RGCKGOZRHPZPFP-UHFFFAOYSA-N
Other name(s) : Alizarine || Alizarin Red || Mordant Red 11 || CHEBI:16866 || SCHEMBL18614
MW : 240.21
Formula : C14H8O4
CAS_number : 72-48-0
PubChem : 6293
UniChem : RGCKGOZRHPZPFP-UHFFFAOYSA-N
Target
Families : Alizarin ligand of proteins in family
Pancreatic_lipase
Protein :
human-PNLIP
References (1)
| Title : Discovery of natural anthraquinones as potent inhibitors against pancreatic lipase: structure-activity relationships and inhibitory mechanism - Chen_2024_J.Enzyme.Inhib.Med.Chem_39_2398561 |
| Author(s) : Chen ZQ , He WY , Yang SY , Ma HH , Zhou J , Li H , Zhu YD , Qian XK , Zou LW |
| Ref : J Enzyme Inhib Med Chem , 39 :2398561 , 2024 |
| Abstract : |
| PubMedSearch : Chen_2024_J.Enzyme.Inhib.Med.Chem_39_2398561 |
| PubMedID: 39223707 |