CHEMBL4518438
AChE IC50 = 0.0465 microM BChE IC50 = 0.0702 microM
General
Type : Triazol
Chemical_Nomenclature : N-[(E)-benzylideneamino]-4-[1-[2-[(2E)-2-benzylidenehydrazinyl]-2-oxoethyl]-3-methyl-5-oxo-1,2,4-triazol-4-yl]benzamide
Canonical SMILES : CC1=NN(C(=O)N1C2=CC=C(C=C2)C(=O)N\/N=C\/C3=CC=CC=C3)CC(=O)N\/N=C\/C4=CC=CC=C4
InChI : InChI=1S\/C26H23N7O3\/c1-19-31-32(18-24(34)29-27-16-20-8-4-2-5-9-20)26(36)33(19)23-14-12-22(13-15-23)25(35)30-28-17-21-10-6-3-7-11-21\/h2-17H,18H2,1H3,(H,29,34)(H,30,35)\/b27-16+,28-17+
InChIKey : UUXGUHRRRWGLJM-ODBZBXGJSA-N
Other name(s) : Compound 6a || BDBM50516976
MW : 481.5
Formula : C26H23N7O3
CAS_number :
PubChem : 155541386
UniChem : UUXGUHRRRWGLJM-ODBZBXGJSA-N
Target
Families : CHEMBL4518438 ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Synthesis of 5-methyl-2,4-dihydro-3H-1,2,4-triazole-3-one's aryl Schiff base derivatives and investigation of carbonic anhydrase and cholinesterase (AChE, BuChE) inhibitory properties - Ozil_2019_Bioorg.Chem_86_705 |
| Author(s) : Ozil M , Balaydin HT , Senturk M |
| Ref : Bioorg Chem , 86 :705 , 2019 |
| Abstract : |
| PubMedSearch : Ozil_2019_Bioorg.Chem_86_705 |
| PubMedID: 30836234 |