Carvacrol-triazole-selanyl-butyl-Cpd18h
AChE IC50 93nM
General
Type : Carvacrol-Thymol, Organoselenium, Triazol
Chemical_Nomenclature : 1-((butylselanyl)methyl)-4-((5-isopropyl-2-methylphenoxy)methyl)-1H-1,2,3-triazole
Canonical SMILES : C1(=CC(=CC=C1C)C(C)C)OCC2=C[N](C[Se]CCCC)N=N2
InChI : InChI=1S\/C18H27N3OSe\/c1-5-6-9-23-13-21-11-17(19-20-21)12-22-18-10-16(14(2)3)8-7-15(18)4\/h7-8,10-11,14H,5-6,9,12-13H2,1-4H3
InChIKey : IJEXAPOSMVLXRZ-UHFFFAOYSA-N
Other name(s) : Compound 18h
Target
Families : Carvacrol-triazole-selanyl-butyl-Cpd18h ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Multifunctional Carvacrol-based Organoselenium hybrids as anticholinesterase and antioxidant candidates for Alzheimer's therapy - Gomes_2025_Bioorg.Med.Chem_132_118447 |
| Author(s) : Gomes LS , Schuler M , Giannini GB , Zapp E , de Oliveira AS , Nascimento V |
| Ref : Bioorganic & Medicinal Chemistry , 132 :118447 , 2025 |
| Abstract : |
| PubMedSearch : Gomes_2025_Bioorg.Med.Chem_132_118447 |
| PubMedID: 41166828 |