DIMP
Not inhibitor of Cholinesterases but surrogate of sarin for designing detectors of OP. Byproduct in the synthesis of Sarin
General
Type : Organophosphate, Surrogate OP
Chemical_Nomenclature : 2-[methyl(propan-2-yloxy)phosphoryl]oxypropane
Canonical SMILES : CC(C)OP(=O)(C)OC(C)C
InChI : InChI=1S\/C7H17O3P\/c1-6(2)9-11(5,8)10-7(3)4\/h6-7H,1-5H3
InChIKey : WOAFDHWYKSOANX-UHFFFAOYSA-N
Other name(s) : diisopropyl methylphosphonate || diisopropyl-methylphosphonate || diisopropylmethylphosphonate || Diisopropyl methanephosphonate || Bis(1-methylethyl) methylphosphonate || Methylphosphonic acid bis(1-methylethyl)ester || CHEBI:77325 || RefChem:587905 || SCHEMBL472052 || SCHEMBL2697259 || CHEMBL1232236
MW : 180.18
Formula : C7H17O3P
CAS_number : 1445-75-6
PubChem : 3073
UniChem : WOAFDHWYKSOANX-UHFFFAOYSA-N
Target
References (39)
| Title : Chemical forensic profiling of compounds related to the chemical weapons convention using 2D and 3D diffusion-ordered NMR spectroscopy - Green_2025_Forensic.Sci.Int_377_112641 |
| Author(s) : Green EL , Ovenden SPB , Mulder RJ , Cosgriff JE , Samuels J , McGill NW , Webster RL |
| Ref : Forensic Science International , 377 :112641 , 2025 |
| Abstract : |
| PubMedSearch : Green_2025_Forensic.Sci.Int_377_112641 |
| PubMedID: 40929903 |
| Title : Chemical forensic profiling of compounds related to the chemical weapons convention using 2D and 3D diffusion-ordered NMR spectroscopy - Green_2025_Forensic.Sci.Int_377_112641 |
| Author(s) : Green EL , Ovenden SPB , Mulder RJ , Cosgriff JE , Samuels J , McGill NW , Webster RL |
| Ref : Forensic Science International , 377 :112641 , 2025 |
| Abstract : |
| PubMedSearch : Green_2025_Forensic.Sci.Int_377_112641 |
| PubMedID: 40929903 |
| Title : Chemical forensic profiling of compounds related to the chemical weapons convention using 2D and 3D diffusion-ordered NMR spectroscopy - Green_2025_Forensic.Sci.Int_377_112641 |
| Author(s) : Green EL , Ovenden SPB , Mulder RJ , Cosgriff JE , Samuels J , McGill NW , Webster RL |
| Ref : Forensic Science International , 377 :112641 , 2025 |
| Abstract : |
| PubMedSearch : Green_2025_Forensic.Sci.Int_377_112641 |
| PubMedID: 40929903 |
| Title : Force Fields for Molecular Modeling of Sarin and its Simulants: DMMP and DIMP - Emelianova_2021_J.Phys.Chem.B_125_4086 |
| Author(s) : Emelianova A , Basharova EA , Kolesnikov AL , Arribas EV , Ivanova EV , Gor GY |
| Ref : J Phys Chem B , 125 :4086 , 2021 |
| Abstract : |
| PubMedSearch : Emelianova_2021_J.Phys.Chem.B_125_4086 |
| PubMedID: 33872511 |
| Title : Force Fields for Molecular Modeling of Sarin and its Simulants: DMMP and DIMP - Emelianova_2021_J.Phys.Chem.B_125_4086 |
| Author(s) : Emelianova A , Basharova EA , Kolesnikov AL , Arribas EV , Ivanova EV , Gor GY |
| Ref : J Phys Chem B , 125 :4086 , 2021 |
| Abstract : |
| PubMedSearch : Emelianova_2021_J.Phys.Chem.B_125_4086 |
| PubMedID: 33872511 |
| Title : Force Fields for Molecular Modeling of Sarin and its Simulants: DMMP and DIMP - Emelianova_2021_J.Phys.Chem.B_125_4086 |
| Author(s) : Emelianova A , Basharova EA , Kolesnikov AL , Arribas EV , Ivanova EV , Gor GY |
| Ref : J Phys Chem B , 125 :4086 , 2021 |
| Abstract : |
| PubMedSearch : Emelianova_2021_J.Phys.Chem.B_125_4086 |
| PubMedID: 33872511 |
| Title : Acetylcholinesterase-functionalized two-dimensional photonic crystal for the sensing of G-series nerve agents - Qi_2019_Anal.Bioanal.Chem_411_2577 |
| Author(s) : Qi F , Yan C , Meng Z , Li S , Xu J , Hu X , Xue M |
| Ref : Anal Bioanal Chem , 411 :2577 , 2019 |
| Abstract : |
| PubMedSearch : Qi_2019_Anal.Bioanal.Chem_411_2577 |
| PubMedID: 30847569 |
| Title : Thermodynamic Studies on a Hydrogen Bonded Acidic 3,5-Bis(trifluoromethyl)phenol-functionalized Polymer as a Gas Chromatography Stationary Phase for Selectively Speciating Chemical Warfare Agents - Read_2019_Anal.Sci_35_671 |
| Author(s) : Read DH , Achyuthan KE , Fix CS , Manginell RP , Moorman MW , Simonson RJ , Wheeler DR , Whiting JJ |
| Ref : Anal Sci , 35 :671 , 2019 |
| Abstract : |
| PubMedSearch : Read_2019_Anal.Sci_35_671 |
| PubMedID: 30773510 |
| Title : Acetylcholinesterase-functionalized two-dimensional photonic crystal for the sensing of G-series nerve agents - Qi_2019_Anal.Bioanal.Chem_411_2577 |
| Author(s) : Qi F , Yan C , Meng Z , Li S , Xu J , Hu X , Xue M |
| Ref : Anal Bioanal Chem , 411 :2577 , 2019 |
| Abstract : |
| PubMedSearch : Qi_2019_Anal.Bioanal.Chem_411_2577 |
| PubMedID: 30847569 |
| Title : Thermodynamic Studies on a Hydrogen Bonded Acidic 3,5-Bis(trifluoromethyl)phenol-functionalized Polymer as a Gas Chromatography Stationary Phase for Selectively Speciating Chemical Warfare Agents - Read_2019_Anal.Sci_35_671 |
| Author(s) : Read DH , Achyuthan KE , Fix CS , Manginell RP , Moorman MW , Simonson RJ , Wheeler DR , Whiting JJ |
| Ref : Anal Sci , 35 :671 , 2019 |
| Abstract : |
| PubMedSearch : Read_2019_Anal.Sci_35_671 |
| PubMedID: 30773510 |
| Title : Acetylcholinesterase-functionalized two-dimensional photonic crystal for the sensing of G-series nerve agents - Qi_2019_Anal.Bioanal.Chem_411_2577 |
| Author(s) : Qi F , Yan C , Meng Z , Li S , Xu J , Hu X , Xue M |
| Ref : Anal Bioanal Chem , 411 :2577 , 2019 |
| Abstract : |
| PubMedSearch : Qi_2019_Anal.Bioanal.Chem_411_2577 |
| PubMedID: 30847569 |
| Title : Thermodynamic Studies on a Hydrogen Bonded Acidic 3,5-Bis(trifluoromethyl)phenol-functionalized Polymer as a Gas Chromatography Stationary Phase for Selectively Speciating Chemical Warfare Agents - Read_2019_Anal.Sci_35_671 |
| Author(s) : Read DH , Achyuthan KE , Fix CS , Manginell RP , Moorman MW , Simonson RJ , Wheeler DR , Whiting JJ |
| Ref : Anal Sci , 35 :671 , 2019 |
| Abstract : |
| PubMedSearch : Read_2019_Anal.Sci_35_671 |
| PubMedID: 30773510 |
| Title : MAPLE Assembled Acetylcholinesterase(-)Polyethylenimine Hybrid and Multilayered Interfaces for Toxic Gases Detection - Dinca_2018_Sensors.(Basel)_18_ |
| Author(s) : Dinca V , Viespe C , Brajnicov S , Constantinoiu I , Moldovan A , Bonciu A , Toader CN , Ginghina RE , Grigoriu N , Dinescu M , Scarisoreanu ND |
| Ref : Sensors (Basel) , 18 : , 2018 |
| Abstract : |
| PubMedSearch : Dinca_2018_Sensors.(Basel)_18_ |
| PubMedID: 30518102 |
| Title : MAPLE Assembled Acetylcholinesterase(-)Polyethylenimine Hybrid and Multilayered Interfaces for Toxic Gases Detection - Dinca_2018_Sensors.(Basel)_18_ |
| Author(s) : Dinca V , Viespe C , Brajnicov S , Constantinoiu I , Moldovan A , Bonciu A , Toader CN , Ginghina RE , Grigoriu N , Dinescu M , Scarisoreanu ND |
| Ref : Sensors (Basel) , 18 : , 2018 |
| Abstract : |
| PubMedSearch : Dinca_2018_Sensors.(Basel)_18_ |
| PubMedID: 30518102 |
| Title : MAPLE Assembled Acetylcholinesterase(-)Polyethylenimine Hybrid and Multilayered Interfaces for Toxic Gases Detection - Dinca_2018_Sensors.(Basel)_18_ |
| Author(s) : Dinca V , Viespe C , Brajnicov S , Constantinoiu I , Moldovan A , Bonciu A , Toader CN , Ginghina RE , Grigoriu N , Dinescu M , Scarisoreanu ND |
| Ref : Sensors (Basel) , 18 : , 2018 |
| Abstract : |
| PubMedSearch : Dinca_2018_Sensors.(Basel)_18_ |
| PubMedID: 30518102 |
| Title : Detection of chemical warfare agent simulants and hydrolysis products in biological samples by paper spray mass spectrometry - McKenna_2017_Analyst_142_1442 |
| Author(s) : McKenna J , Dhummakupt ES , Connell T , Demond PS , Miller DB , Michael Nilles J , Manicke NE , Glaros T |
| Ref : Analyst , 142 :1442 , 2017 |
| Abstract : |
| PubMedSearch : McKenna_2017_Analyst_142_1442 |
| PubMedID: 28338135 |
| Title : Detection of chemical warfare agent simulants and hydrolysis products in biological samples by paper spray mass spectrometry - McKenna_2017_Analyst_142_1442 |
| Author(s) : McKenna J , Dhummakupt ES , Connell T , Demond PS , Miller DB , Michael Nilles J , Manicke NE , Glaros T |
| Ref : Analyst , 142 :1442 , 2017 |
| Abstract : |
| PubMedSearch : McKenna_2017_Analyst_142_1442 |
| PubMedID: 28338135 |
| Title : Detection of chemical warfare agent simulants and hydrolysis products in biological samples by paper spray mass spectrometry - McKenna_2017_Analyst_142_1442 |
| Author(s) : McKenna J , Dhummakupt ES , Connell T , Demond PS , Miller DB , Michael Nilles J , Manicke NE , Glaros T |
| Ref : Analyst , 142 :1442 , 2017 |
| Abstract : |
| PubMedSearch : McKenna_2017_Analyst_142_1442 |
| PubMedID: 28338135 |
| Title : Real-time trace detection and identification of chemical warfare agent simulants using recent advances in proton transfer reaction time-of-flight mass spectrometry - Petersson_2009_Rapid.Commun.Mass.Spectrom_23_3875 |
| Author(s) : Petersson F , Sulzer P , Mayhew CA , Watts P , Jordan A , Mark L , Mark TD |
| Ref : Rapid Commun Mass Spectrom , 23 :3875 , 2009 |
| Abstract : |
| PubMedSearch : Petersson_2009_Rapid.Commun.Mass.Spectrom_23_3875 |
| PubMedID: 19902419 |
| Title : Real-time trace detection and identification of chemical warfare agent simulants using recent advances in proton transfer reaction time-of-flight mass spectrometry - Petersson_2009_Rapid.Commun.Mass.Spectrom_23_3875 |
| Author(s) : Petersson F , Sulzer P , Mayhew CA , Watts P , Jordan A , Mark L , Mark TD |
| Ref : Rapid Commun Mass Spectrom , 23 :3875 , 2009 |
| Abstract : |
| PubMedSearch : Petersson_2009_Rapid.Commun.Mass.Spectrom_23_3875 |
| PubMedID: 19902419 |
| Title : Real-time trace detection and identification of chemical warfare agent simulants using recent advances in proton transfer reaction time-of-flight mass spectrometry - Petersson_2009_Rapid.Commun.Mass.Spectrom_23_3875 |
| Author(s) : Petersson F , Sulzer P , Mayhew CA , Watts P , Jordan A , Mark L , Mark TD |
| Ref : Rapid Commun Mass Spectrom , 23 :3875 , 2009 |
| Abstract : |
| PubMedSearch : Petersson_2009_Rapid.Commun.Mass.Spectrom_23_3875 |
| PubMedID: 19902419 |
| Title : Elevated frequency of sister chromatid exchanges of lymphocytes in sarin-exposed victims of the Tokyo sarin disaster 3 years after the event - Li_2004_Toxicology_201_209 |
| Author(s) : Li Q , Hirata Y , Kawada T , Minami M |
| Ref : Toxicology , 201 :209 , 2004 |
| Abstract : |
| PubMedSearch : Li_2004_Toxicology_201_209 |
| PubMedID: 15297034 |
| Title : Elevated frequency of sister chromatid exchanges of lymphocytes in sarin-exposed victims of the Tokyo sarin disaster 3 years after the event - Li_2004_Toxicology_201_209 |
| Author(s) : Li Q , Hirata Y , Kawada T , Minami M |
| Ref : Toxicology , 201 :209 , 2004 |
| Abstract : |
| PubMedSearch : Li_2004_Toxicology_201_209 |
| PubMedID: 15297034 |
| Title : Elevated frequency of sister chromatid exchanges of lymphocytes in sarin-exposed victims of the Tokyo sarin disaster 3 years after the event - Li_2004_Toxicology_201_209 |
| Author(s) : Li Q , Hirata Y , Kawada T , Minami M |
| Ref : Toxicology , 201 :209 , 2004 |
| Abstract : |
| PubMedSearch : Li_2004_Toxicology_201_209 |
| PubMedID: 15297034 |
| Title : Two-generation reproductive study in mink fed diisopropyl methylphosphonate (DIMP) - Bucci_2003_Reprod.Toxicol_17_327 |
| Author(s) : Bucci TJ , Kovatch RM , Mercieca MD , Perman V , Klingensmith JS |
| Ref : Reprod Toxicol , 17 :327 , 2003 |
| Abstract : |
| PubMedSearch : Bucci_2003_Reprod.Toxicol_17_327 |
| PubMedID: 12759102 |
| Title : Two-generation reproductive study in mink fed diisopropyl methylphosphonate (DIMP) - Bucci_2003_Reprod.Toxicol_17_327 |
| Author(s) : Bucci TJ , Kovatch RM , Mercieca MD , Perman V , Klingensmith JS |
| Ref : Reprod Toxicol , 17 :327 , 2003 |
| Abstract : |
| PubMedSearch : Bucci_2003_Reprod.Toxicol_17_327 |
| PubMedID: 12759102 |
| Title : Two-generation reproductive study in mink fed diisopropyl methylphosphonate (DIMP) - Bucci_2003_Reprod.Toxicol_17_327 |
| Author(s) : Bucci TJ , Kovatch RM , Mercieca MD , Perman V , Klingensmith JS |
| Ref : Reprod Toxicol , 17 :327 , 2003 |
| Abstract : |
| PubMedSearch : Bucci_2003_Reprod.Toxicol_17_327 |
| PubMedID: 12759102 |
| Title : The by-products generated during sarin synthesis in the Tokyo sarin disaster induced inhibition of natural killer and cytotoxic T lymphocyte activity - Li_2000_Toxicology_146_209 |
| Author(s) : Li Q , Hirata Y , Piao S , Minami M |
| Ref : Toxicology , 146 :209 , 2000 |
| Abstract : |
| PubMedSearch : Li_2000_Toxicology_146_209 |
| PubMedID: 10814853 |
| Title : The by-products generated during sarin synthesis in the Tokyo sarin disaster induced inhibition of natural killer and cytotoxic T lymphocyte activity - Li_2000_Toxicology_146_209 |
| Author(s) : Li Q , Hirata Y , Piao S , Minami M |
| Ref : Toxicology , 146 :209 , 2000 |
| Abstract : |
| PubMedSearch : Li_2000_Toxicology_146_209 |
| PubMedID: 10814853 |
| Title : The by-products generated during sarin synthesis in the Tokyo sarin disaster induced inhibition of natural killer and cytotoxic T lymphocyte activity - Li_2000_Toxicology_146_209 |
| Author(s) : Li Q , Hirata Y , Piao S , Minami M |
| Ref : Toxicology , 146 :209 , 2000 |
| Abstract : |
| PubMedSearch : Li_2000_Toxicology_146_209 |
| PubMedID: 10814853 |
| Title : The sources, fate, and toxicity of chemical warfare agent degradation products - Munro_1999_Environ.Health.Perspect_107_933 |
| Author(s) : Munro NB , Talmage SS , Griffin GD , Waters LC , Watson AP , King JF , Hauschild V |
| Ref : Environmental Health Perspectives , 107 :933 , 1999 |
| Abstract : |
| PubMedSearch : Munro_1999_Environ.Health.Perspect_107_933 |
| PubMedID: 10585900 |
| Title : The sources, fate, and toxicity of chemical warfare agent degradation products - Munro_1999_Environ.Health.Perspect_107_933 |
| Author(s) : Munro NB , Talmage SS , Griffin GD , Waters LC , Watson AP , King JF , Hauschild V |
| Ref : Environmental Health Perspectives , 107 :933 , 1999 |
| Abstract : |
| PubMedSearch : Munro_1999_Environ.Health.Perspect_107_933 |
| PubMedID: 10585900 |
| Title : The sources, fate, and toxicity of chemical warfare agent degradation products - Munro_1999_Environ.Health.Perspect_107_933 |
| Author(s) : Munro NB , Talmage SS , Griffin GD , Waters LC , Watson AP , King JF , Hauschild V |
| Ref : Environmental Health Perspectives , 107 :933 , 1999 |
| Abstract : |
| PubMedSearch : Munro_1999_Environ.Health.Perspect_107_933 |
| PubMedID: 10585900 |
| Title : Elevated frequency of sister chromatid exchanges in lymphocytes of victims of the Tokyo sarin disaster and in experiments exposing lymphocytes to by-products of sarin synthesis - Li_1998_Toxicol.Lett_98_95 |
| Author(s) : Li Q , Minami M , ClementJG , Boulet CA |
| Ref : Toxicol Lett , 98 :95 , 1998 |
| Abstract : |
| PubMedSearch : Li_1998_Toxicol.Lett_98_95 |
| PubMedID: 9776566 |
| Title : Biological monitoring of metabolites of sarin and its by-products in human urine samples - Minami_1998_J.Toxicol.Sci_23_250 |
| Author(s) : Minami M , Hui DM , Wang Z , Katsumata M , Inagaki H , Li Q , Inuzuka S , Mashiko K , Yamamoto Y , Ootsuka T , Boulet CA , Clement JG |
| Ref : Journal of Toxicological Sciences , 23 Suppl 2 :250 , 1998 |
| Abstract : |
| PubMedSearch : Minami_1998_J.Toxicol.Sci_23_250 |
| PubMedID: 9760476 |
| Title : Elevated frequency of sister chromatid exchanges in lymphocytes of victims of the Tokyo sarin disaster and in experiments exposing lymphocytes to by-products of sarin synthesis - Li_1998_Toxicol.Lett_98_95 |
| Author(s) : Li Q , Minami M , ClementJG , Boulet CA |
| Ref : Toxicol Lett , 98 :95 , 1998 |
| Abstract : |
| PubMedSearch : Li_1998_Toxicol.Lett_98_95 |
| PubMedID: 9776566 |
| Title : Elevated frequency of sister chromatid exchanges in lymphocytes of victims of the Tokyo sarin disaster and in experiments exposing lymphocytes to by-products of sarin synthesis - Li_1998_Toxicol.Lett_98_95 |
| Author(s) : Li Q , Minami M , ClementJG , Boulet CA |
| Ref : Toxicol Lett , 98 :95 , 1998 |
| Abstract : |
| PubMedSearch : Li_1998_Toxicol.Lett_98_95 |
| PubMedID: 9776566 |
| Title : Biological monitoring of metabolites of sarin and its by-products in human urine samples - Minami_1998_J.Toxicol.Sci_23_250 |
| Author(s) : Minami M , Hui DM , Wang Z , Katsumata M , Inagaki H , Li Q , Inuzuka S , Mashiko K , Yamamoto Y , Ootsuka T , Boulet CA , Clement JG |
| Ref : Journal of Toxicological Sciences , 23 Suppl 2 :250 , 1998 |
| Abstract : |
| PubMedSearch : Minami_1998_J.Toxicol.Sci_23_250 |
| PubMedID: 9760476 |
| Title : Biological monitoring of metabolites of sarin and its by-products in human urine samples - Minami_1998_J.Toxicol.Sci_23_250 |
| Author(s) : Minami M , Hui DM , Wang Z , Katsumata M , Inagaki H , Li Q , Inuzuka S , Mashiko K , Yamamoto Y , Ootsuka T , Boulet CA , Clement JG |
| Ref : Journal of Toxicological Sciences , 23 Suppl 2 :250 , 1998 |
| Abstract : |
| PubMedSearch : Minami_1998_J.Toxicol.Sci_23_250 |
| PubMedID: 9760476 |