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Surrogate OP

General

Derivatives of the organophosphate nerve agents designed as building blocks of less toxic compounds for biochemical studies, and for understanding toxicity or mechanism of reactivation of cholinesterases inhibited by OPs
Inhibitor Main targeted enzyme families Type Structure
ANMP ACHE Organophosphate Surrogate OP pNP Novichok
BPMP ACHE BCHE Organophosphate Surrogate OP Nerve Agent G-series Derivative of Soman
BIMP ACHE BCHE Derivative of Sarin Organophosphate Surrogate OP Nerve Agent G-series
EMP-MeCyC ACHE Cyanide Organophosphate Flu-OP Nerve Agent V-series Surrogate OP Coumarin
EMP-DDAO ACHE Organophosphate Flu-OP Nerve Agent V-series Surrogate OP Derivative of Tacrine
CMP-MeCyC ACHE Organophosphate Flu-OP Nerve Agent G-series Surrogate OP Coumarin Derivative of Sarin Chromen
CMP-DDAO ACHE Organophosphate Flu-OP Nerve Agent G-series Surrogate OP Derivative of Tacrine
PMP-MeCyC ACHE Organophosphate Flu-OP Nerve Agent G-series Surrogate OP Coumarin Derivative of Soman Chromen Cyanide
PMP-DDAO ACHE Organophosphate Flu-OP Nerve Agent G-series Surrogate OP Derivative of Soman Derivative of Tacrine
IMP-MeCyC ACHE Organophosphate Flu-OP Nerve Agent G-series Surrogate OP Derivative of Sarin Chromen Coumarin
IMP-DDAO ACHE Organophosphate Flu-OP Nerve Agent G-series Surrogate OP Derivative of Tacrine Derivative of Sarin
IMP-pNP ACHE Cholesterol_esterase Organophosphate Surrogate OP Nerve Agent G-series pNP Derivative of Sarin
IMP-pNP-F ACHE Organophosphate Surrogate OP Nerve Agent G-series pNP Derivative of Sarin
PIMP ACHE Organophosphate Surrogate OP Nerve Agent G-series Derivative of Sarin Phthalimido Isoindole
NEMP-F ACHE Organophosphate Surrogate OP Nerve Agent V-series Derivative of VX pNP
NEMP ACHE Cholesterol_esterase Organophosphate Surrogate OP Nerve Agent V-series Derivative of VX pNP
TEMP ACHE Organophosphate Surrogate OP Nerve Agent V-series Derivative of VX
NEDPA ACHE Cholesterol_esterase Organophosphate Surrogate OP Nerve Agent G-series pNP